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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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Smart API
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L1000
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
talastine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antihistaminics
3579
16188-61-7
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
talastine monohydrochloride
talastine hydrochloride
talastine HCl
ahanon
talastine
benzylphthalazone
Molecular weight: 307.40
Formula: C19H21N3O
CLOGP: 2.15
LIPINSKI: 0
HAC: 4
HDO: 0
TPSA: 35.91
ALOGS: -3.65
ROTB: 5
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
R06AB07
RESPIRATORY SYSTEM
ANTIHISTAMINES FOR SYSTEMIC USE
ANTIHISTAMINES FOR SYSTEMIC USE
Substituted alkylamines
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
7.76
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Histamine H1 receptor
GPCR
P35367
HRH1_HUMAN
ANTAGONIST
SCIENTIFIC LITERATURE
SCIENTIFIC LITERATURE
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External reference:
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ID
Source
16188-76-4
SECONDARY_CAS_RN
2402
INN_ID
49AB2PA48B
UNII
65624
PUBCHEM_CID
C0084711
UMLSCUI
C009376
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:135308
CHEBI
CHEMBL1742439
ChEMBL_ID
D07399
KEGG_DRUG
DB13349
DRUGBANK_ID
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Pharmaceutical products:
None
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talastine