methiodal 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
radiopharmaceuticals, iodine-contained 3346 143-47-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methiodal
  • iodomethanesulfonic acid
  • methiodal sodium
major descriptor (66-86); on-line search METHANESULFONATES (74-86), ALKYL SULFONATES (73), SULFONIC ACIDS (66-72); INDEX MEDICUS search METHIODAL (66-86)
  • Molecular weight: 222
  • Formula: CH3IO3S
  • CLOGP: -1.03
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 54.37
  • ALOGS: -1.37
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,CSF1R,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT1,FLT3,GRK2,GSK3B,IGF1R,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,KIT,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAPK1,MAPK10,MAPK12,MAPK7,MAPK8,MAPK9,MAPKAPK2,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM1,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70 70
kinase-selectivity-class AURKA,AXL,BRAF,CDK1,CDK4,CDK9,DYRK1B,EPHB4,GRK2,JAK2,MAP2K6,MAPK7,PIK3CG,PRKDC,STK33,SYK,TEK,ZAP70 18
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AA09 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, nephrotropic, high osmolar X-ray contrast media

Related Drugs by ATC class:

V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast media 9 drugs
acetrizoic aciddiatrizoatediodoneiocarmic acidiodamideioglicic acidiotalamic acidioxitalamic acidmetrizoic acid

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D09213 KEGG_DRUG
C0066116 UMLSCUI
CHEBI:134912 CHEBI
CHEMBL2110978 ChEMBL_ID
DB13321 DRUGBANK_ID
CHEMBL2106907 ChEMBL_ID
31346 PUBCHEM_CID
C100285 MESH_SUPPLEMENTAL_RECORD_UI
126-31-8 SECONDARY_CAS_RN
H20847G0I0 UNII
002348 NDDF
004887 NDDF
1881 INN_ID

Pharmaceutical products:

None