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iodamide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| iodine-containing contrast media | 1452 | 440-58-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An ionic monomeric contrast medium. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GRK3,GSK3B,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,KIT,MAP2K6,MAP3K14,MAP3K2,MAP3K21,MAP3K3,MAP3K7,MAP4K1,MAPK1,MAPK10,MAPK12,MAPK7,MAPK8,MAPK9,MAPKAPK2,MAPKAPK5,MARK4,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM1,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70 | 72 | |||
| kinase-selectivity-class | ACVR2A,ACVR2B,ALK,AURKA,AURKB,AURKC,AXL,BRAF,CAMK2B,CAMK2D,CDK16,CDK2,CDK3,CDK4,CDK7,CDK9,CLK2,CLK4,DDR1,DYRK1A,DYRK1B,DYRK3,EIF2AK3,EPHB4,ERBB2,FLT4,GRK2,GSK3A,GSK3B,HIPK2,JAK2,MAP2K3,MAP2K4,MAP2K6,MAP3K14,MAP3K2,MAP3K21,MAP3K7,MAP4K1,MAPK1,MAPK12,MAPK7,MARK4,PDK1,PDK4,PIK3CB,PIK3CD,PIK3CG,PIM3,PRKAA1,PRKCZ,PRKDC,SIK2,SIK3,STK10,STK33,SYK,TEK,TGFBR1,TTK,UHMK1,ULK1,ULK2 | 63 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| July 25, 1978 | FDA | BRACCO |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V08AA03 | VARIOUS CONTRAST MEDIA X-RAY CONTRAST MEDIA, IODINATED Watersoluble, nephrotropic, high osmolar X-ray contrast media |
| MeSH PA | D003287 | Contrast Media |
| MeSH PA | D064907 | Diagnostic Uses of Chemicals |
| CHEBI has role | CHEBI:37338 | radioopaque medium |
Related Drugs by ATC class:
V08AA Watersoluble, nephrotropic, high osmolar X-ray contrast media 9 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Arteriography of cerebral arteries | indication | 3258003 | |
| Splenoportogram by splenic arteriography | indication | 24715008 | |
| Cholangiogram | indication | 28367004 | |
| Aortography | indication | 54640009 | |
| Intraosseous venography | indication | 75233009 | |
| Renal arteriography | indication | 79516005 | |
| Hysterosalpingogram | indication | 168884001 | |
| Venography: peripheral | indication | 168981008 | |
| Radiographic imaging procedure | indication | 363680008 | |
| Retrograde pyelogram | indication | 405250000 | |
| Computed tomography of entire head | indication | 408754009 | |
| Peripheral Arteriography | indication | ||
| Digestive System Radiography | indication | ||
| Retrograde Cystourethrography | indication | ||
| Acute nephropathy | contraindication | 58574008 | |
| Hepatic failure | contraindication | 59927004 | |
| Pregnancy, function | contraindication | 289908002 | |
| Pheochromocytoma | contraindication | 302835009 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.56 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000007778 | NUI |
| D01376 | KEGG_DRUG |
| 4017761 | VANDF |
| C0021961 | UMLSCUI |
| CHEBI:31703 | CHEBI |
| CHEMBL1201239 | ChEMBL_ID |
| CHEMBL1201172 | ChEMBL_ID |
| D007451 | MESH_DESCRIPTOR_UI |
| DB08948 | DRUGBANK_ID |
| 1922 | INN_ID |
| 18656-21-8 | SECONDARY_CAS_RN |
| 4RII332O0R | UNII |
| 3723 | PUBCHEM_CID |
| 29455 | RXNORM |
| 4899 | MMSL |
| d01452 | MMSL |
| 002351 | NDDF |
| 002352 | NDDF |
| C006753 | MESH_SUPPLEMENTAL_RECORD_UI |
Pharmaceutical products:
None