Stem definition | Drug id | CAS RN |
---|---|---|
2803 | 99-66-1 |
Dose | Unit | Route |
---|---|---|
1.50 | g | O |
1.50 | g | P |
1.50 | g | R |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 1.30 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 1.80 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 289.15 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 99 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.14 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 0.16 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.08 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 12 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Feb. 28, 1978 | FDA | ABBVIE |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Seizure | 1934.76 | 10.41 | 1820 | 109330 | 127689 | 53110227 |
Epilepsy | 1130.04 | 10.41 | 691 | 110459 | 25076 | 53212840 |
Hyperammonaemic encephalopathy | 1100.48 | 10.41 | 328 | 110822 | 1723 | 53236193 |
Hyperammonaemia | 1087.92 | 10.41 | 408 | 110742 | 4741 | 53233175 |
Drug interaction | 950.09 | 10.41 | 1664 | 109486 | 217665 | 53020251 |
Status epilepticus | 932.20 | 10.41 | 507 | 110643 | 14677 | 53223239 |
Foetal anticonvulsant syndrome | 618.11 | 10.41 | 156 | 110994 | 372 | 53237544 |
Somnolence | 557.83 | 10.41 | 1138 | 110012 | 166596 | 53071320 |
Rheumatoid arthritis | 550.45 | 10.41 | 25 | 111125 | 314506 | 52923410 |
Toxicity to various agents | 510.98 | 10.41 | 1293 | 109857 | 218305 | 53019611 |
Aggression | 493.25 | 10.41 | 401 | 110749 | 23002 | 53214914 |
Generalised tonic-clonic seizure | 472.08 | 10.41 | 427 | 110723 | 28331 | 53209585 |
Sopor | 465.00 | 10.41 | 371 | 110779 | 20713 | 53217203 |
Intentional overdose | 454.07 | 10.41 | 627 | 110523 | 66578 | 53171338 |
Arthralgia | 426.58 | 10.41 | 192 | 110958 | 439591 | 52798325 |
Ammonia increased | 424.62 | 10.41 | 202 | 110948 | 4371 | 53233545 |
Dysmorphism | 423.81 | 10.41 | 164 | 110986 | 2086 | 53235830 |
Pain | 415.99 | 10.41 | 370 | 110780 | 588028 | 52649888 |
Psychotic disorder | 407.97 | 10.41 | 366 | 110784 | 24019 | 53213897 |
Mania | 401.25 | 10.41 | 270 | 110880 | 11559 | 53226357 |
Petit mal epilepsy | 383.12 | 10.41 | 174 | 110976 | 3374 | 53234542 |
Overdose | 368.44 | 10.41 | 740 | 110410 | 106996 | 53130920 |
Coma | 360.93 | 10.41 | 538 | 110612 | 61245 | 53176671 |
Extrapyramidal disorder | 354.87 | 10.41 | 255 | 110895 | 12147 | 53225769 |
Drug abuse | 353.69 | 10.41 | 550 | 110600 | 64976 | 53172940 |
Multiple-drug resistance | 353.59 | 10.41 | 160 | 110990 | 3075 | 53234841 |
Foetal exposure during pregnancy | 351.79 | 10.41 | 397 | 110753 | 34318 | 53203598 |
Granulocytopenia | 344.86 | 10.41 | 187 | 110963 | 5373 | 53232543 |
Intentional self-injury | 343.34 | 10.41 | 338 | 110812 | 24946 | 53212970 |
Tremor | 330.94 | 10.41 | 777 | 110373 | 124959 | 53112957 |
Suicide attempt | 327.62 | 10.41 | 498 | 110652 | 57670 | 53180246 |
Neuroleptic malignant syndrome | 327.43 | 10.41 | 240 | 110910 | 11793 | 53226123 |
Parkinsonism | 320.81 | 10.41 | 212 | 110938 | 8801 | 53229115 |
Drug level increased | 315.20 | 10.41 | 293 | 110857 | 20128 | 53217788 |
Sedation | 310.32 | 10.41 | 345 | 110805 | 29330 | 53208586 |
Speech disorder developmental | 299.07 | 10.41 | 89 | 111061 | 464 | 53237452 |
Joint swelling | 297.59 | 10.41 | 63 | 111087 | 234575 | 53003341 |
Fatigue | 286.89 | 10.41 | 693 | 110457 | 729813 | 52508103 |
Dyspnoea | 277.18 | 10.41 | 500 | 110650 | 585732 | 52652184 |
Abnormal behaviour | 274.24 | 10.41 | 280 | 110870 | 21586 | 53216330 |
Agitation | 266.01 | 10.41 | 455 | 110695 | 58171 | 53179745 |
Developmental delay | 252.05 | 10.41 | 97 | 111053 | 1214 | 53236702 |
Ataxia | 248.05 | 10.41 | 222 | 110928 | 14515 | 53223401 |
Antipsychotic drug level increased | 245.99 | 10.41 | 126 | 111024 | 3213 | 53234703 |
Drug reaction with eosinophilia and systemic symptoms | 244.21 | 10.41 | 321 | 110829 | 32479 | 53205437 |
Depressed level of consciousness | 242.44 | 10.41 | 419 | 110731 | 54009 | 53183907 |
Infusion related reaction | 236.22 | 10.41 | 25 | 111125 | 155932 | 53081984 |
Drug level decreased | 233.03 | 10.41 | 156 | 110994 | 6618 | 53231298 |
Cognitive disorder | 227.91 | 10.41 | 366 | 110784 | 44412 | 53193504 |
Diarrhoea | 227.05 | 10.41 | 617 | 110533 | 624929 | 52612987 |
Peripheral swelling | 224.11 | 10.41 | 75 | 111075 | 206033 | 53031883 |
Bipolar disorder | 222.09 | 10.41 | 159 | 110991 | 7527 | 53230389 |
Abdominal discomfort | 219.39 | 10.41 | 93 | 111057 | 220969 | 53016947 |
Autism spectrum disorder | 217.71 | 10.41 | 75 | 111075 | 667 | 53237249 |
Myoclonic epilepsy | 215.95 | 10.41 | 82 | 111068 | 987 | 53236929 |
Arthropathy | 205.91 | 10.41 | 26 | 111124 | 141427 | 53096489 |
Anticonvulsant drug level increased | 200.06 | 10.41 | 84 | 111066 | 1336 | 53236580 |
Salivary hypersecretion | 196.88 | 10.41 | 142 | 111008 | 6801 | 53231115 |
Learning disorder | 196.36 | 10.41 | 64 | 111086 | 471 | 53237445 |
Contraindicated product administered | 192.47 | 10.41 | 27 | 111123 | 135602 | 53102314 |
Intellectual disability | 192.25 | 10.41 | 69 | 111081 | 700 | 53237216 |
Swelling | 190.23 | 10.41 | 80 | 111070 | 191025 | 53046891 |
Schizoaffective disorder | 186.47 | 10.41 | 91 | 111059 | 2086 | 53235830 |
Hypernatraemia | 182.35 | 10.41 | 136 | 111014 | 6861 | 53231055 |
Sudden unexplained death in epilepsy | 177.35 | 10.41 | 52 | 111098 | 255 | 53237661 |
Anticonvulsant drug level decreased | 173.52 | 10.41 | 73 | 111077 | 1167 | 53236749 |
Nausea | 172.98 | 10.41 | 901 | 110249 | 755190 | 52482726 |
Electrocardiogram QT prolonged | 171.03 | 10.41 | 369 | 110781 | 56034 | 53181882 |
Abortion spontaneous | 170.90 | 10.41 | 330 | 110820 | 46305 | 53191611 |
Encephalopathy | 168.65 | 10.41 | 287 | 110863 | 36521 | 53201395 |
Irritability | 167.15 | 10.41 | 260 | 110890 | 30693 | 53207223 |
Sinusitis | 165.45 | 10.41 | 72 | 111078 | 168492 | 53069424 |
Nasopharyngitis | 163.65 | 10.41 | 99 | 111051 | 192196 | 53045720 |
Pain in extremity | 160.07 | 10.41 | 216 | 110934 | 284834 | 52953082 |
Anticonvulsant drug level above therapeutic | 159.52 | 10.41 | 54 | 111096 | 453 | 53237463 |
Partial seizures | 159.36 | 10.41 | 113 | 111037 | 5267 | 53232649 |
Hand deformity | 157.76 | 10.41 | 4 | 111146 | 84845 | 53153071 |
Hypothermia | 156.13 | 10.41 | 163 | 110987 | 12893 | 53225023 |
Schizophrenia | 155.73 | 10.41 | 146 | 111004 | 10133 | 53227783 |
Disturbance in attention | 152.15 | 10.41 | 264 | 110886 | 34119 | 53203797 |
Disorientation | 150.98 | 10.41 | 284 | 110866 | 39075 | 53198841 |
Altered state of consciousness | 150.28 | 10.41 | 220 | 110930 | 24616 | 53213300 |
Hallucination, auditory | 149.86 | 10.41 | 152 | 110998 | 11621 | 53226295 |
Electroencephalogram abnormal | 148.53 | 10.41 | 95 | 111055 | 3726 | 53234190 |
Systemic lupus erythematosus | 146.44 | 10.41 | 40 | 111110 | 125374 | 53112542 |
Glossodynia | 144.56 | 10.41 | 19 | 111131 | 100272 | 53137644 |
Treatment noncompliance | 144.03 | 10.41 | 252 | 110898 | 32783 | 53205133 |
Congenital nose malformation | 143.82 | 10.41 | 44 | 111106 | 256 | 53237660 |
Cough | 142.85 | 10.41 | 196 | 110954 | 256697 | 52981219 |
Psychomotor retardation | 140.30 | 10.41 | 90 | 111060 | 3548 | 53234368 |
Delusion | 140.16 | 10.41 | 148 | 111002 | 11861 | 53226055 |
Drug intolerance | 140.04 | 10.41 | 133 | 111017 | 205360 | 53032556 |
Hypotonia | 137.38 | 10.41 | 128 | 111022 | 8813 | 53229103 |
Stevens-Johnson syndrome | 136.24 | 10.41 | 209 | 110941 | 24373 | 53213543 |
Drug withdrawal convulsions | 134.72 | 10.41 | 63 | 111087 | 1309 | 53236607 |
Learning disability | 134.59 | 10.41 | 39 | 111111 | 182 | 53237734 |
Back pain | 130.94 | 10.41 | 178 | 110972 | 234069 | 53003847 |
Exposure during pregnancy | 129.91 | 10.41 | 560 | 110590 | 124300 | 53113616 |
Psychomotor skills impaired | 127.94 | 10.41 | 72 | 111078 | 2227 | 53235689 |
Catatonia | 126.99 | 10.41 | 88 | 111062 | 3952 | 53233964 |
Headache | 126.77 | 10.41 | 632 | 110518 | 536189 | 52701727 |
Hypersensitivity | 125.04 | 10.41 | 153 | 110997 | 210512 | 53027404 |
Suicidal ideation | 120.62 | 10.41 | 337 | 110813 | 60174 | 53177742 |
Discomfort | 120.14 | 10.41 | 26 | 111124 | 95446 | 53142470 |
Behaviour disorder | 119.71 | 10.41 | 71 | 111079 | 2429 | 53235487 |
Dysarthria | 117.94 | 10.41 | 261 | 110889 | 40307 | 53197609 |
Fanconi syndrome | 117.52 | 10.41 | 55 | 111095 | 1145 | 53236771 |
Pruritus | 116.82 | 10.41 | 276 | 110874 | 293556 | 52944360 |
Drug ineffective for unapproved indication | 114.59 | 10.41 | 176 | 110974 | 20544 | 53217372 |
Bradyphrenia | 114.20 | 10.41 | 102 | 111048 | 6648 | 53231268 |
Myoclonus | 112.26 | 10.41 | 151 | 110999 | 15613 | 53222303 |
Muscle rigidity | 111.50 | 10.41 | 125 | 111025 | 10716 | 53227200 |
Anticonvulsant drug level below therapeutic | 108.81 | 10.41 | 42 | 111108 | 530 | 53237386 |
Psychomotor hyperactivity | 108.30 | 10.41 | 119 | 111031 | 9977 | 53227939 |
Drug resistance | 106.81 | 10.41 | 167 | 110983 | 19795 | 53218121 |
Psychogenic seizure | 106.29 | 10.41 | 58 | 111092 | 1687 | 53236229 |
Paradoxical drug reaction | 105.86 | 10.41 | 73 | 111077 | 3252 | 53234664 |
Product substitution issue | 105.47 | 10.41 | 147 | 111003 | 15719 | 53222197 |
Completed suicide | 104.82 | 10.41 | 566 | 110584 | 137635 | 53100281 |
Hyperprolactinaemia | 103.71 | 10.41 | 72 | 111078 | 3243 | 53234673 |
Blood creatine phosphokinase increased | 103.60 | 10.41 | 203 | 110947 | 28782 | 53209134 |
Hypomania | 103.54 | 10.41 | 84 | 111066 | 4798 | 53233118 |
Injection site pain | 102.70 | 10.41 | 54 | 111096 | 113337 | 53124579 |
Focal dyscognitive seizures | 99.90 | 10.41 | 67 | 111083 | 2850 | 53235066 |
Febrile neutropenia | 99.51 | 10.41 | 47 | 111103 | 104889 | 53133027 |
Confusional state | 98.83 | 10.41 | 718 | 110432 | 193503 | 53044413 |
Tardive dyskinesia | 98.73 | 10.41 | 102 | 111048 | 7968 | 53229948 |
Language disorder | 98.69 | 10.41 | 57 | 111093 | 1854 | 53236062 |
Anaemia | 97.63 | 10.41 | 276 | 110874 | 276442 | 52961474 |
Congenital hand malformation | 96.23 | 10.41 | 33 | 111117 | 289 | 53237627 |
Educational problem | 95.97 | 10.41 | 34 | 111116 | 331 | 53237585 |
Carnitine deficiency | 95.72 | 10.41 | 28 | 111122 | 136 | 53237780 |
Pneumonia aspiration | 95.58 | 10.41 | 217 | 110933 | 34084 | 53203832 |
Akathisia | 95.38 | 10.41 | 103 | 111047 | 8468 | 53229448 |
Atonic seizures | 94.77 | 10.41 | 39 | 111111 | 588 | 53237328 |
Meningomyelocele | 94.63 | 10.41 | 38 | 111112 | 536 | 53237380 |
Stupor | 94.03 | 10.41 | 72 | 111078 | 3779 | 53234137 |
Product residue present | 93.44 | 10.41 | 74 | 111076 | 4082 | 53233834 |
Congenital foot malformation | 92.53 | 10.41 | 29 | 111121 | 185 | 53237731 |
Nystagmus | 91.94 | 10.41 | 86 | 111064 | 5950 | 53231966 |
Wound | 91.55 | 10.41 | 38 | 111112 | 91519 | 53146397 |
Mental disorder | 89.89 | 10.41 | 173 | 110977 | 24203 | 53213713 |
Skull malformation | 89.12 | 10.41 | 32 | 111118 | 325 | 53237591 |
Arthritis | 87.66 | 10.41 | 36 | 111114 | 87262 | 53150654 |
Cerebral atrophy | 87.41 | 10.41 | 77 | 111073 | 4927 | 53232989 |
Plasma cell myeloma | 86.27 | 10.41 | 3 | 111147 | 47871 | 53190045 |
Speech disorder | 83.84 | 10.41 | 224 | 110926 | 38957 | 53198959 |
Herpes zoster | 83.80 | 10.41 | 25 | 111125 | 73994 | 53163922 |
Delirium | 83.80 | 10.41 | 232 | 110918 | 41197 | 53196719 |
Thrombocytopenia | 82.49 | 10.41 | 533 | 110617 | 138194 | 53099722 |
Impaired healing | 81.76 | 10.41 | 17 | 111133 | 64188 | 53173728 |
Therapeutic product effect decreased | 81.32 | 10.41 | 85 | 111065 | 125570 | 53112346 |
Injection site erythema | 80.63 | 10.41 | 30 | 111120 | 77219 | 53160697 |
Rhabdomyolysis | 80.14 | 10.41 | 237 | 110913 | 43686 | 53194230 |
Cardiac failure congestive | 79.90 | 10.41 | 47 | 111103 | 92710 | 53145206 |
Low set ears | 78.28 | 10.41 | 28 | 111122 | 281 | 53237635 |
Death | 77.71 | 10.41 | 432 | 110718 | 356800 | 52881116 |
Neuropathy peripheral | 77.25 | 10.41 | 61 | 111089 | 103126 | 53134790 |
Rash | 77.03 | 10.41 | 579 | 110571 | 445612 | 52792304 |
Psychiatric symptom | 76.27 | 10.41 | 71 | 111079 | 4882 | 53233034 |
Limb malformation | 76.03 | 10.41 | 32 | 111118 | 512 | 53237404 |
Toxic epidermal necrolysis | 75.89 | 10.41 | 158 | 110992 | 23392 | 53214524 |
Talipes | 75.45 | 10.41 | 44 | 111106 | 1458 | 53236458 |
Respiratory depression | 75.38 | 10.41 | 112 | 111038 | 12694 | 53225222 |
Abdominal pain upper | 75.34 | 10.41 | 145 | 111005 | 166146 | 53071770 |
Impulsive behaviour | 74.85 | 10.41 | 44 | 111106 | 1480 | 53236436 |
Infection | 74.72 | 10.41 | 154 | 110996 | 172051 | 53065865 |
Dyskinesia | 73.23 | 10.41 | 187 | 110963 | 31646 | 53206270 |
Infantile spasms | 73.04 | 10.41 | 26 | 111124 | 257 | 53237659 |
Chest pain | 72.85 | 10.41 | 182 | 110968 | 190003 | 53047913 |
Propofol infusion syndrome | 72.73 | 10.41 | 35 | 111115 | 777 | 53237139 |
Differential white blood cell count abnormal | 72.72 | 10.41 | 34 | 111116 | 706 | 53237210 |
Persecutory delusion | 71.66 | 10.41 | 53 | 111097 | 2639 | 53235277 |
Hypertelorism | 71.17 | 10.41 | 28 | 111122 | 373 | 53237543 |
Psoriasis | 71.04 | 10.41 | 47 | 111103 | 87042 | 53150874 |
Osteoarthritis | 70.87 | 10.41 | 29 | 111121 | 70457 | 53167459 |
Motor developmental delay | 70.48 | 10.41 | 21 | 111129 | 110 | 53237806 |
Affect lability | 70.13 | 10.41 | 92 | 111058 | 9283 | 53228633 |
Stomatitis | 69.81 | 10.41 | 61 | 111089 | 98097 | 53139819 |
Bipolar I disorder | 69.54 | 10.41 | 44 | 111106 | 1693 | 53236223 |
Loss of consciousness | 68.60 | 10.41 | 440 | 110710 | 113772 | 53124144 |
Urticaria | 68.31 | 10.41 | 111 | 111039 | 135774 | 53102142 |
Pleurothotonus | 68.22 | 10.41 | 40 | 111110 | 1339 | 53236577 |
Myocarditis | 67.89 | 10.41 | 86 | 111064 | 8382 | 53229534 |
Arnold-Chiari malformation | 67.10 | 10.41 | 29 | 111121 | 497 | 53237419 |
Ear malformation | 67.01 | 10.41 | 23 | 111127 | 202 | 53237714 |
Tonic convulsion | 67.01 | 10.41 | 38 | 111112 | 1193 | 53236723 |
Mental impairment | 66.60 | 10.41 | 108 | 111042 | 13201 | 53224715 |
Weight increased | 66.54 | 10.41 | 685 | 110465 | 203882 | 53034034 |
Drug level below therapeutic | 66.32 | 10.41 | 58 | 111092 | 3675 | 53234241 |
Product dose omission issue | 65.41 | 10.41 | 194 | 110956 | 191426 | 53046490 |
Gingival hypertrophy | 64.84 | 10.41 | 40 | 111110 | 1471 | 53236445 |
Congenital eyelid malformation | 64.59 | 10.41 | 13 | 111137 | 3 | 53237913 |
Dystonia | 64.26 | 10.41 | 105 | 111045 | 12916 | 53225000 |
Acidosis hyperchloraemic | 63.96 | 10.41 | 25 | 111125 | 327 | 53237589 |
Oculogyric crisis | 62.86 | 10.41 | 39 | 111111 | 1449 | 53236467 |
Influenza | 62.29 | 10.41 | 64 | 111086 | 95315 | 53142601 |
Resting tremor | 62.07 | 10.41 | 31 | 111119 | 748 | 53237168 |
Intentional product use issue | 62.05 | 10.41 | 37 | 111113 | 72457 | 53165459 |
Lethargy | 62.02 | 10.41 | 249 | 110901 | 53511 | 53184405 |
Malignant neoplasm progression | 61.96 | 10.41 | 36 | 111114 | 71505 | 53166411 |
Atrial septal defect | 61.52 | 10.41 | 74 | 111076 | 6840 | 53231076 |
Ileus paralytic | 61.37 | 10.41 | 61 | 111089 | 4550 | 53233366 |
Metabolic encephalopathy | 60.99 | 10.41 | 68 | 111082 | 5793 | 53232123 |
Strabismus | 59.88 | 10.41 | 42 | 111108 | 1923 | 53235993 |
Brain oedema | 59.83 | 10.41 | 104 | 111046 | 13454 | 53224462 |
Gastrointestinal haemorrhage | 59.48 | 10.41 | 48 | 111102 | 80282 | 53157634 |
Blood prolactin increased | 58.91 | 10.41 | 51 | 111099 | 3188 | 53234728 |
Toxic encephalopathy | 58.67 | 10.41 | 67 | 111083 | 5860 | 53232056 |
Nasal congestion | 58.52 | 10.41 | 19 | 111131 | 53268 | 53184648 |
Suicidal behaviour | 58.49 | 10.41 | 46 | 111104 | 2512 | 53235404 |
Leukopenia | 58.46 | 10.41 | 305 | 110845 | 73158 | 53164758 |
Blood pressure increased | 58.12 | 10.41 | 129 | 111021 | 140350 | 53097566 |
Stillbirth | 57.64 | 10.41 | 71 | 111079 | 6726 | 53231190 |
Productive cough | 57.59 | 10.41 | 23 | 111127 | 56706 | 53181210 |
Mitochondrial DNA mutation | 57.07 | 10.41 | 21 | 111129 | 230 | 53237686 |
Dementia | 57.07 | 10.41 | 115 | 111035 | 16635 | 53221281 |
Seizure cluster | 56.61 | 10.41 | 20 | 111130 | 193 | 53237723 |
Dyspnoea exertional | 56.32 | 10.41 | 22 | 111128 | 54978 | 53182938 |
Hyperlactacidaemia | 55.92 | 10.41 | 46 | 111104 | 2679 | 53235237 |
Abdominal pain | 55.83 | 10.41 | 309 | 110841 | 255594 | 52982322 |
Neurodevelopmental disorder | 55.41 | 10.41 | 12 | 111138 | 9 | 53237907 |
Atrial fibrillation | 55.37 | 10.41 | 92 | 111058 | 111560 | 53126356 |
Flushing | 55.06 | 10.41 | 40 | 111110 | 70560 | 53167356 |
Paranoia | 54.86 | 10.41 | 91 | 111059 | 11333 | 53226583 |
White blood cell count increased | 54.79 | 10.41 | 216 | 110934 | 46029 | 53191887 |
Musculoskeletal stiffness | 54.62 | 10.41 | 109 | 111041 | 123259 | 53114657 |
Restlessness | 54.54 | 10.41 | 155 | 110995 | 27932 | 53209984 |
Microcephaly | 54.53 | 10.41 | 29 | 111121 | 800 | 53237116 |
Folliculitis | 53.81 | 10.41 | 3 | 111147 | 31706 | 53206210 |
Fluid retention | 53.70 | 10.41 | 23 | 111127 | 54378 | 53183538 |
Antipsychotic drug level decreased | 53.36 | 10.41 | 19 | 111131 | 188 | 53237728 |
Enuresis | 53.24 | 10.41 | 41 | 111109 | 2170 | 53235746 |
Psoriatic arthropathy | 53.24 | 10.41 | 17 | 111133 | 48173 | 53189743 |
Pericarditis | 52.20 | 10.41 | 35 | 111115 | 64371 | 53173545 |
Hypoaesthesia | 51.90 | 10.41 | 126 | 111024 | 132869 | 53105047 |
Alopecia | 51.86 | 10.41 | 282 | 110868 | 234301 | 53003615 |
Myalgia | 51.67 | 10.41 | 127 | 111023 | 133364 | 53104552 |
Attention deficit hyperactivity disorder | 51.62 | 10.41 | 43 | 111107 | 2549 | 53235367 |
Injection site reaction | 51.52 | 10.41 | 21 | 111129 | 51145 | 53186771 |
Communication disorder | 51.46 | 10.41 | 42 | 111108 | 2419 | 53235497 |
Cerebellar atrophy | 51.29 | 10.41 | 26 | 111124 | 648 | 53237268 |
Bronchitis | 51.16 | 10.41 | 97 | 111053 | 111802 | 53126114 |
Mental status changes | 51.13 | 10.41 | 190 | 110960 | 39381 | 53198535 |
Injection site pruritus | 50.95 | 10.41 | 12 | 111138 | 41577 | 53196339 |
Thrombosis | 50.68 | 10.41 | 32 | 111118 | 60761 | 53177155 |
Helicobacter infection | 50.45 | 10.41 | 10 | 111140 | 39059 | 53198857 |
Muscle injury | 49.95 | 10.41 | 3 | 111147 | 29763 | 53208153 |
Hypokinesia | 49.93 | 10.41 | 94 | 111056 | 12933 | 53224983 |
Drug hypersensitivity | 49.65 | 10.41 | 336 | 110814 | 264906 | 52973010 |
Rhinorrhoea | 49.25 | 10.41 | 25 | 111125 | 53553 | 53184363 |
Knee arthroplasty | 49.22 | 10.41 | 6 | 111144 | 33563 | 53204353 |
Bone pain | 49.18 | 10.41 | 22 | 111128 | 50700 | 53187216 |
Neutrophil count increased | 48.49 | 10.41 | 102 | 111048 | 15208 | 53222708 |
Poisoning | 48.27 | 10.41 | 96 | 111054 | 13754 | 53224162 |
Depressed mood | 48.19 | 10.41 | 178 | 110972 | 36786 | 53201130 |
Spina bifida | 47.71 | 10.41 | 26 | 111124 | 754 | 53237162 |
Grandiosity | 47.67 | 10.41 | 18 | 111132 | 213 | 53237703 |
Injection site swelling | 47.16 | 10.41 | 15 | 111135 | 42613 | 53195303 |
Wheezing | 47.09 | 10.41 | 40 | 111110 | 65235 | 53172681 |
Gastrointestinal disorder | 46.66 | 10.41 | 72 | 111078 | 89932 | 53147984 |
Angiofibroma | 46.54 | 10.41 | 15 | 111135 | 106 | 53237810 |
Selective eating disorder | 46.48 | 10.41 | 36 | 111114 | 1922 | 53235994 |
Congenital scoliosis | 46.47 | 10.41 | 10 | 111140 | 7 | 53237909 |
Musculoskeletal pain | 46.28 | 10.41 | 53 | 111097 | 75147 | 53162769 |
Asthenia | 45.88 | 10.41 | 476 | 110674 | 343114 | 52894802 |
Hepatic failure | 45.49 | 10.41 | 171 | 110979 | 35635 | 53202281 |
Blood pressure systolic increased | 45.43 | 10.41 | 9 | 111141 | 35168 | 53202748 |
Disease progression | 45.16 | 10.41 | 90 | 111060 | 101830 | 53136086 |
Abortion induced | 45.13 | 10.41 | 81 | 111069 | 10745 | 53227171 |
Intra-abdominal pressure increased | 44.74 | 10.41 | 17 | 111133 | 205 | 53237711 |
Bradykinesia | 44.43 | 10.41 | 50 | 111100 | 4303 | 53233613 |
Carnitine decreased | 44 | 10.41 | 9 | 111141 | 3 | 53237913 |
Chills | 43.58 | 10.41 | 96 | 111054 | 104752 | 53133164 |
Lip disorder | 43.57 | 10.41 | 29 | 111121 | 1218 | 53236698 |
Chest discomfort | 43.35 | 10.41 | 89 | 111061 | 99606 | 53138310 |
Pectus excavatum | 43.33 | 10.41 | 13 | 111137 | 70 | 53237846 |
Anger | 43.33 | 10.41 | 86 | 111064 | 12304 | 53225612 |
Coordination abnormal | 43.06 | 10.41 | 84 | 111066 | 11867 | 53226049 |
Hypertension | 42.96 | 10.41 | 284 | 110866 | 225147 | 53012769 |
Logorrhoea | 42.91 | 10.41 | 38 | 111112 | 2448 | 53235468 |
Craniosynostosis | 42.81 | 10.41 | 15 | 111135 | 141 | 53237775 |
Ventricular septal defect | 42.76 | 10.41 | 49 | 111101 | 4301 | 53233615 |
Myopia | 42.54 | 10.41 | 31 | 111119 | 1508 | 53236408 |
Affective disorder | 42.43 | 10.41 | 55 | 111095 | 5484 | 53232432 |
Refusal of treatment by patient | 42.42 | 10.41 | 55 | 111095 | 5485 | 53232431 |
Interstitial lung disease | 42.19 | 10.41 | 36 | 111114 | 58586 | 53179330 |
Tonic clonic movements | 42.03 | 10.41 | 29 | 111121 | 1293 | 53236623 |
Dyspraxia | 42.00 | 10.41 | 17 | 111133 | 245 | 53237671 |
Hot flush | 41.88 | 10.41 | 23 | 111127 | 47137 | 53190779 |
Hallucination | 41.78 | 10.41 | 222 | 110928 | 53616 | 53184300 |
Hallucinations, mixed | 40.77 | 10.41 | 48 | 111102 | 4338 | 53233578 |
Mood swings | 40.50 | 10.41 | 103 | 111047 | 17383 | 53220533 |
Pain in jaw | 40.45 | 10.41 | 17 | 111133 | 40652 | 53197264 |
Drop attacks | 40.39 | 10.41 | 23 | 111127 | 728 | 53237188 |
Eosinophilic pleural effusion | 40.36 | 10.41 | 11 | 111139 | 39 | 53237877 |
Amenorrhoea | 40.32 | 10.41 | 71 | 111079 | 9278 | 53228638 |
Reflexes abnormal | 40.25 | 10.41 | 22 | 111128 | 642 | 53237274 |
Inflammation | 40.02 | 10.41 | 36 | 111114 | 57100 | 53180816 |
Psychotic symptom | 39.81 | 10.41 | 26 | 111124 | 1057 | 53236859 |
Dry skin | 39.66 | 10.41 | 23 | 111127 | 45737 | 53192179 |
Asterixis | 39.65 | 10.41 | 28 | 111122 | 1296 | 53236620 |
Acute hepatic failure | 39.26 | 10.41 | 99 | 111051 | 16621 | 53221295 |
Oropharyngeal oedema | 39.20 | 10.41 | 16 | 111134 | 236 | 53237680 |
Injection site bruising | 38.64 | 10.41 | 15 | 111135 | 37631 | 53200285 |
Adjustment disorder with mixed anxiety and depressed mood | 38.63 | 10.41 | 12 | 111138 | 74 | 53237842 |
Epistaxis | 38.53 | 10.41 | 52 | 111098 | 68658 | 53169258 |
Astigmatism | 38.51 | 10.41 | 25 | 111125 | 1006 | 53236910 |
Oral mucosa erosion | 38.49 | 10.41 | 26 | 111124 | 1119 | 53236797 |
Limbic encephalitis | 38.42 | 10.41 | 16 | 111134 | 249 | 53237667 |
Antipsychotic drug level above therapeutic | 38.40 | 10.41 | 25 | 111125 | 1011 | 53236905 |
Tachycardia | 38.35 | 10.41 | 369 | 110781 | 107843 | 53130073 |
Malaise | 38.28 | 10.41 | 520 | 110630 | 357097 | 52880819 |
Gene mutation | 38.12 | 10.41 | 27 | 111123 | 1256 | 53236660 |
Muscle spasms | 38.11 | 10.41 | 148 | 111002 | 134647 | 53103269 |
Psychotic behaviour | 38.01 | 10.41 | 21 | 111129 | 626 | 53237290 |
Change in seizure presentation | 37.85 | 10.41 | 16 | 111134 | 259 | 53237657 |
Depressive symptom | 37.68 | 10.41 | 40 | 111110 | 3224 | 53234692 |
Asthma | 37.39 | 10.41 | 110 | 111040 | 108862 | 53129054 |
Dysmetria | 37.14 | 10.41 | 18 | 111132 | 406 | 53237510 |
Posture abnormal | 36.88 | 10.41 | 34 | 111116 | 2309 | 53235607 |
Hyperthermia | 36.86 | 10.41 | 65 | 111085 | 8504 | 53229412 |
Metabolic acidosis | 36.84 | 10.41 | 180 | 110970 | 42062 | 53195854 |
Congenital anomaly | 36.80 | 10.41 | 29 | 111121 | 1588 | 53236328 |
Personal relationship issue | 36.57 | 10.41 | 10 | 111140 | 36 | 53237880 |
Poor sucking reflex | 36.39 | 10.41 | 14 | 111136 | 175 | 53237741 |
Hypertonia | 36.23 | 10.41 | 47 | 111103 | 4690 | 53233226 |
Blood lactic acid increased | 36.22 | 10.41 | 53 | 111097 | 5925 | 53231991 |
Pneumatosis | 36.13 | 10.41 | 18 | 111132 | 432 | 53237484 |
Antipsychotic drug level below therapeutic | 36.05 | 10.41 | 16 | 111134 | 293 | 53237623 |
Dyslexia | 36.05 | 10.41 | 16 | 111134 | 293 | 53237623 |
Galactorrhoea | 35.94 | 10.41 | 43 | 111107 | 3952 | 53233964 |
Sinus rhythm | 35.87 | 10.41 | 21 | 111129 | 701 | 53237215 |
Aphasia | 35.84 | 10.41 | 143 | 111007 | 30635 | 53207281 |
Oropharyngeal pain | 35.79 | 10.41 | 72 | 111078 | 81196 | 53156720 |
Lordosis | 35.76 | 10.41 | 16 | 111134 | 299 | 53237617 |
Haematochezia | 35.71 | 10.41 | 22 | 111128 | 42336 | 53195580 |
Treatment failure | 35.65 | 10.41 | 142 | 111008 | 128261 | 53109655 |
Pneumonia | 35.44 | 10.41 | 616 | 110534 | 406553 | 52831363 |
Throat irritation | 35.31 | 10.41 | 11 | 111139 | 31670 | 53206246 |
Neovascularisation | 35.29 | 10.41 | 20 | 111130 | 627 | 53237289 |
Delusion of grandeur | 35.28 | 10.41 | 13 | 111137 | 143 | 53237773 |
Cogwheel rigidity | 35.18 | 10.41 | 29 | 111121 | 1694 | 53236222 |
Congenital hair disorder | 35.17 | 10.41 | 10 | 111140 | 43 | 53237873 |
Hyperchloraemia | 35.13 | 10.41 | 21 | 111129 | 729 | 53237187 |
Clinodactyly | 35.00 | 10.41 | 12 | 111138 | 105 | 53237811 |
Camptodactyly congenital | 34.94 | 10.41 | 8 | 111142 | 10 | 53237906 |
Anaphylactic reaction | 34.93 | 10.41 | 42 | 111108 | 58284 | 53179632 |
C-reactive protein abnormal | 34.74 | 10.41 | 6 | 111144 | 25864 | 53212052 |
Fungal infection | 34.53 | 10.41 | 12 | 111138 | 32234 | 53205682 |
Apathy | 34.40 | 10.41 | 62 | 111088 | 8250 | 53229666 |
Myocardial infarction | 34.30 | 10.41 | 100 | 111050 | 99254 | 53138662 |
Sluggishness | 34.26 | 10.41 | 46 | 111104 | 4746 | 53233170 |
Urinary incontinence | 34.14 | 10.41 | 141 | 111009 | 30680 | 53207236 |
Bradycardia neonatal | 33.96 | 10.41 | 22 | 111128 | 882 | 53237034 |
Cataract | 33.88 | 10.41 | 32 | 111118 | 49588 | 53188328 |
Partial seizures with secondary generalisation | 33.80 | 10.41 | 16 | 111134 | 342 | 53237574 |
Hyperglycinaemia | 33.74 | 10.41 | 7 | 111143 | 3 | 53237913 |
Speech sound disorder | 33.74 | 10.41 | 7 | 111143 | 3 | 53237913 |
Cardiac failure | 33.73 | 10.41 | 81 | 111069 | 85763 | 53152153 |
Contusion | 33.65 | 10.41 | 118 | 111032 | 110614 | 53127302 |
Neutropenia | 33.41 | 10.41 | 491 | 110659 | 158694 | 53079222 |
Obesity | 33.38 | 10.41 | 93 | 111057 | 16569 | 53221347 |
Encephalitis autoimmune | 33.34 | 10.41 | 25 | 111125 | 1271 | 53236645 |
Weight decreased | 33.19 | 10.41 | 321 | 110829 | 234627 | 53003289 |
Hypophosphataemic osteomalacia | 33.12 | 10.41 | 13 | 111137 | 172 | 53237744 |
Weight gain poor | 33.12 | 10.41 | 21 | 111129 | 811 | 53237105 |
Gaze palsy | 33.07 | 10.41 | 26 | 111124 | 1419 | 53236497 |
Multiple congenital abnormalities | 33.06 | 10.41 | 18 | 111132 | 521 | 53237395 |
Anticonvulsant drug level abnormal | 33.00 | 10.41 | 9 | 111141 | 32 | 53237884 |
Retinogram abnormal | 32.98 | 10.41 | 12 | 111138 | 127 | 53237789 |
Porphyria acute | 32.85 | 10.41 | 18 | 111132 | 528 | 53237388 |
Plagiocephaly | 32.71 | 10.41 | 10 | 111140 | 58 | 53237858 |
Polydipsia | 32.56 | 10.41 | 38 | 111112 | 3402 | 53234514 |
Necrosis ischaemic | 32.50 | 10.41 | 21 | 111129 | 838 | 53237078 |
Unresponsive to stimuli | 32.49 | 10.41 | 147 | 111003 | 33279 | 53204637 |
Diverticulitis | 32.47 | 10.41 | 17 | 111133 | 35784 | 53202132 |
Cystitis | 32.44 | 10.41 | 30 | 111120 | 46958 | 53190958 |
Arachnodactyly | 32.42 | 10.41 | 10 | 111140 | 60 | 53237856 |
Irritable bowel syndrome | 32.38 | 10.41 | 26 | 111124 | 43606 | 53194310 |
Neoplasm progression | 32.27 | 10.41 | 11 | 111139 | 29908 | 53208008 |
Psychiatric decompensation | 32.24 | 10.41 | 25 | 111125 | 1337 | 53236579 |
Localised infection | 32.15 | 10.41 | 8 | 111142 | 26708 | 53211208 |
Mydriasis | 31.93 | 10.41 | 72 | 111078 | 11254 | 53226662 |
Angiomyolipoma | 31.83 | 10.41 | 13 | 111137 | 192 | 53237724 |
Palpitations | 31.82 | 10.41 | 108 | 111042 | 102240 | 53135676 |
Rabbit syndrome | 31.76 | 10.41 | 15 | 111135 | 319 | 53237597 |
Nipple disorder | 31.62 | 10.41 | 11 | 111139 | 101 | 53237815 |
COVID-19 | 31.32 | 10.41 | 19 | 111131 | 36869 | 53201047 |
Drug level above therapeutic | 31.21 | 10.41 | 40 | 111110 | 3944 | 53233972 |
Dysgraphia | 31.20 | 10.41 | 34 | 111116 | 2823 | 53235093 |
Hypersexuality | 31.13 | 10.41 | 17 | 111133 | 495 | 53237421 |
Gait disturbance | 31.04 | 10.41 | 484 | 110666 | 158358 | 53079558 |
Breast hyperplasia | 31.03 | 10.41 | 14 | 111136 | 267 | 53237649 |
Pulmonary arterial hypertension | 30.98 | 10.41 | 9 | 111141 | 27113 | 53210803 |
Nephrogenic diabetes insipidus | 30.84 | 10.41 | 21 | 111129 | 916 | 53237000 |
Renal tubular acidosis | 30.69 | 10.41 | 27 | 111123 | 1724 | 53236192 |
Screaming | 30.68 | 10.41 | 36 | 111114 | 3241 | 53234675 |
Hepatic function abnormal | 30.59 | 10.41 | 155 | 110995 | 36744 | 53201172 |
Paraesthesia | 30.56 | 10.41 | 149 | 111001 | 127366 | 53110550 |
Hip arthroplasty | 30.47 | 10.41 | 10 | 111140 | 27852 | 53210064 |
Congenital joint malformation | 30.46 | 10.41 | 7 | 111143 | 9 | 53237907 |
Device expulsion | 30.40 | 10.41 | 12 | 111138 | 29801 | 53208115 |
Drooling | 30.32 | 10.41 | 37 | 111113 | 3471 | 53234445 |
Constipation | 30.21 | 10.41 | 266 | 110884 | 198146 | 53039770 |
Glycosuria | 30.04 | 10.41 | 23 | 111127 | 1207 | 53236709 |
Metabolic disorder | 29.86 | 10.41 | 46 | 111104 | 5381 | 53232535 |
Respiratory disorder neonatal | 29.82 | 10.41 | 21 | 111129 | 968 | 53236948 |
Night sweats | 29.67 | 10.41 | 18 | 111132 | 34929 | 53202987 |
Ovarian granulosa-theca cell tumour | 29.66 | 10.41 | 8 | 111142 | 27 | 53237889 |
Deafness congenital | 29.64 | 10.41 | 7 | 111143 | 11 | 53237905 |
Inappropriate antidiuretic hormone secretion | 29.51 | 10.41 | 83 | 111067 | 14868 | 53223048 |
Foetal death | 29.28 | 10.41 | 62 | 111088 | 9285 | 53228631 |
Hyponatraemia | 29.01 | 10.41 | 350 | 110800 | 108257 | 53129659 |
Cleft palate | 28.97 | 10.41 | 21 | 111129 | 1013 | 53236903 |
Osteonecrosis of jaw | 28.81 | 10.41 | 20 | 111130 | 36126 | 53201790 |
Congenital oral malformation | 28.80 | 10.41 | 12 | 111138 | 187 | 53237729 |
Strabismus congenital | 28.80 | 10.41 | 8 | 111142 | 31 | 53237885 |
Automatism | 28.77 | 10.41 | 9 | 111141 | 57 | 53237859 |
Skin ulcer | 28.76 | 10.41 | 20 | 111130 | 36099 | 53201817 |
Mucosal inflammation | 28.73 | 10.41 | 28 | 111122 | 42756 | 53195160 |
Conjunctival hyperaemia | 28.66 | 10.41 | 29 | 111121 | 2210 | 53235706 |
Tooth malformation | 28.63 | 10.41 | 6 | 111144 | 3 | 53237913 |
Balance disorder | 28.63 | 10.41 | 255 | 110895 | 72952 | 53164964 |
High arched palate | 28.38 | 10.41 | 9 | 111141 | 60 | 53237856 |
Lower respiratory tract infection | 28.28 | 10.41 | 96 | 111054 | 90885 | 53147031 |
Acute kidney injury | 28.28 | 10.41 | 366 | 110784 | 253502 | 52984414 |
Brief psychotic disorder, with postpartum onset | 28.21 | 10.41 | 8 | 111142 | 34 | 53237882 |
Motor dysfunction | 28.20 | 10.41 | 57 | 111093 | 8261 | 53229655 |
Verbal abuse | 27.81 | 10.41 | 10 | 111140 | 102 | 53237814 |
Tic | 27.67 | 10.41 | 23 | 111127 | 1359 | 53236557 |
Accidental overdose | 27.63 | 10.41 | 103 | 111047 | 21376 | 53216540 |
Neck pain | 27.44 | 10.41 | 52 | 111098 | 59964 | 53177952 |
Hallucination, visual | 27.38 | 10.41 | 94 | 111056 | 18738 | 53219178 |
Metastases to bone | 27.04 | 10.41 | 4 | 111146 | 19324 | 53218592 |
Congenital central nervous system anomaly | 26.97 | 10.41 | 14 | 111136 | 367 | 53237549 |
Respiratory acidosis | 26.89 | 10.41 | 48 | 111102 | 6340 | 53231576 |
Pulmonary hypertension | 26.68 | 10.41 | 23 | 111127 | 37247 | 53200669 |
Hepatic enzyme increased | 26.60 | 10.41 | 154 | 110996 | 126041 | 53111875 |
Cellulitis | 26.58 | 10.41 | 76 | 111074 | 75913 | 53162003 |
Blood gases abnormal | 26.57 | 10.41 | 17 | 111133 | 667 | 53237249 |
General physical health deterioration | 26.54 | 10.41 | 188 | 110962 | 146754 | 53091162 |
Gastrooesophageal reflux disease | 26.54 | 10.41 | 86 | 111064 | 82577 | 53155339 |
Polycystic ovaries | 26.47 | 10.41 | 28 | 111122 | 2248 | 53235668 |
Dacryostenosis congenital | 26.43 | 10.41 | 6 | 111144 | 7 | 53237909 |
Reading disorder | 26.36 | 10.41 | 18 | 111132 | 789 | 53237127 |
Subileus | 26.32 | 10.41 | 33 | 111117 | 3183 | 53234733 |
Polydactyly | 26.14 | 10.41 | 14 | 111136 | 392 | 53237524 |
Congenital flat feet | 25.88 | 10.41 | 5 | 111145 | 0 | 53237916 |
Leukocytosis | 25.72 | 10.41 | 111 | 111039 | 24623 | 53213293 |
Urinary tract infection | 25.57 | 10.41 | 349 | 110801 | 239554 | 52998362 |
Product use in unapproved indication | 25.41 | 10.41 | 351 | 110799 | 111938 | 53125978 |
Borderline personality disorder | 25.29 | 10.41 | 17 | 111133 | 726 | 53237190 |
Hypermobility syndrome | 25.18 | 10.41 | 17 | 111133 | 731 | 53237185 |
Hepatotoxicity | 25.17 | 10.41 | 120 | 111030 | 27760 | 53210156 |
Physical assault | 25.12 | 10.41 | 19 | 111131 | 979 | 53236937 |
Echolalia | 25.11 | 10.41 | 11 | 111139 | 195 | 53237721 |
Monocytosis | 25.04 | 10.41 | 13 | 111137 | 341 | 53237575 |
Palmar-plantar erythrodysaesthesia syndrome | 24.99 | 10.41 | 7 | 111143 | 21599 | 53216317 |
Obsessive-compulsive disorder | 24.82 | 10.41 | 34 | 111116 | 3576 | 53234340 |
Pancreatitis | 24.81 | 10.41 | 173 | 110977 | 45969 | 53191947 |
Rotavirus infection | 24.67 | 10.41 | 12 | 111138 | 273 | 53237643 |
Lennox-Gastaut syndrome | 24.63 | 10.41 | 12 | 111138 | 274 | 53237642 |
Depression | 24.59 | 10.41 | 526 | 110624 | 182526 | 53055390 |
Vestibular migraine | 24.56 | 10.41 | 11 | 111139 | 206 | 53237710 |
Mood altered | 24.39 | 10.41 | 74 | 111076 | 13827 | 53224089 |
Euphoric mood | 24.38 | 10.41 | 38 | 111112 | 4491 | 53233425 |
Hereditary ataxia | 24.27 | 10.41 | 7 | 111143 | 32 | 53237884 |
Akinesia | 24.27 | 10.41 | 25 | 111125 | 1946 | 53235970 |
Injection site rash | 24.22 | 10.41 | 3 | 111147 | 16576 | 53221340 |
Eye movement disorder | 24.21 | 10.41 | 40 | 111110 | 4965 | 53232951 |
Pulmonary fibrosis | 24.14 | 10.41 | 10 | 111140 | 24125 | 53213791 |
Precocious puberty | 24.13 | 10.41 | 11 | 111139 | 215 | 53237701 |
Erythema | 24.08 | 10.41 | 210 | 110940 | 156759 | 53081157 |
Cerebrovascular accident | 24.00 | 10.41 | 125 | 111025 | 105049 | 53132867 |
Rash maculo-papular | 23.99 | 10.41 | 124 | 111026 | 29625 | 53208291 |
Lactate pyruvate ratio increased | 23.95 | 10.41 | 9 | 111141 | 105 | 53237811 |
Illogical thinking | 23.85 | 10.41 | 8 | 111142 | 65 | 53237851 |
Prognathism | 23.85 | 10.41 | 8 | 111142 | 65 | 53237851 |
Joint stiffness | 23.81 | 10.41 | 17 | 111133 | 30266 | 53207650 |
Bipolar II disorder | 23.68 | 10.41 | 12 | 111138 | 299 | 53237617 |
Dysgeusia | 23.55 | 10.41 | 33 | 111117 | 42898 | 53195018 |
Staring | 23.43 | 10.41 | 22 | 111128 | 1529 | 53236387 |
Cerebellar syndrome | 23.35 | 10.41 | 33 | 111117 | 3574 | 53234342 |
Conductive deafness | 23.33 | 10.41 | 8 | 111142 | 70 | 53237846 |
Lymphangioleiomyomatosis | 23.32 | 10.41 | 10 | 111140 | 168 | 53237748 |
Social avoidant behaviour | 23.25 | 10.41 | 30 | 111120 | 2978 | 53234938 |
Breast cancer | 23.24 | 10.41 | 42 | 111108 | 49316 | 53188600 |
Fibromyalgia | 23.08 | 10.41 | 35 | 111115 | 44040 | 53193876 |
Metabolic syndrome | 22.94 | 10.41 | 21 | 111129 | 1413 | 53236503 |
Retinitis pigmentosa | 22.94 | 10.41 | 9 | 111141 | 119 | 53237797 |
Conversion disorder | 22.91 | 10.41 | 23 | 111127 | 1736 | 53236180 |
Growth retardation | 22.83 | 10.41 | 19 | 111131 | 1125 | 53236791 |
Fluid overload | 22.71 | 10.41 | 15 | 111135 | 27816 | 53210100 |
Apraxia | 22.70 | 10.41 | 23 | 111127 | 1755 | 53236161 |
Vomiting | 22.59 | 10.41 | 828 | 110322 | 496311 | 52741605 |
Surgery | 22.55 | 10.41 | 20 | 111130 | 31944 | 53205972 |
Right ventricular failure | 22.41 | 10.41 | 4 | 111146 | 16839 | 53221077 |
Full blood count decreased | 22.40 | 10.41 | 11 | 111139 | 24018 | 53213898 |
Stereotypy | 22.34 | 10.41 | 13 | 111137 | 429 | 53237487 |
Disinhibition | 22.34 | 10.41 | 17 | 111133 | 884 | 53237032 |
Diplopia | 22.22 | 10.41 | 94 | 111056 | 20671 | 53217245 |
Pneumonitis | 22.18 | 10.41 | 19 | 111131 | 30869 | 53207047 |
Loss of personal independence in daily activities | 22.15 | 10.41 | 73 | 111077 | 69742 | 53168174 |
Schizoaffective disorder bipolar type | 22.09 | 10.41 | 9 | 111141 | 132 | 53237784 |
Illiteracy | 22.07 | 10.41 | 6 | 111144 | 21 | 53237895 |
Agranulocytosis | 22.01 | 10.41 | 103 | 111047 | 23646 | 53214270 |
Hirsutism | 21.86 | 10.41 | 18 | 111132 | 1050 | 53236866 |
Hypotonia neonatal | 21.78 | 10.41 | 18 | 111132 | 1055 | 53236861 |
Pancreatitis necrotising | 21.61 | 10.41 | 21 | 111129 | 1524 | 53236392 |
Basal cell carcinoma | 21.49 | 10.41 | 11 | 111139 | 23458 | 53214458 |
Tachyphrenia | 21.41 | 10.41 | 20 | 111130 | 1381 | 53236535 |
Upper respiratory tract infection | 21.41 | 10.41 | 73 | 111077 | 69024 | 53168892 |
Mutism | 21.27 | 10.41 | 20 | 111130 | 1393 | 53236523 |
Developmental regression | 21.25 | 10.41 | 6 | 111144 | 25 | 53237891 |
Oral pain | 21.19 | 10.41 | 15 | 111135 | 26822 | 53211094 |
Epileptic encephalopathy | 21.14 | 10.41 | 11 | 111139 | 290 | 53237626 |
Right ventricular hypertrophy | 21.04 | 10.41 | 15 | 111135 | 705 | 53237211 |
Blood count abnormal | 21.00 | 10.41 | 8 | 111142 | 20307 | 53217609 |
Eosinophilia | 20.86 | 10.41 | 94 | 111056 | 21241 | 53216675 |
Intentional product misuse | 20.85 | 10.41 | 175 | 110975 | 49217 | 53188699 |
Feeling hot | 20.80 | 10.41 | 34 | 111116 | 41510 | 53196406 |
Intelligence test abnormal | 20.70 | 10.41 | 4 | 111146 | 0 | 53237916 |
Anomaly of orbit, congenital | 20.70 | 10.41 | 4 | 111146 | 0 | 53237916 |
Optic nerve hypoplasia | 20.70 | 10.41 | 4 | 111146 | 0 | 53237916 |
Injection site haemorrhage | 20.70 | 10.41 | 10 | 111140 | 22041 | 53215875 |
Renal failure | 20.68 | 10.41 | 153 | 110997 | 118299 | 53119617 |
Heart rate decreased | 20.67 | 10.41 | 28 | 111122 | 36919 | 53200997 |
Congenital cystic kidney disease | 20.59 | 10.41 | 12 | 111138 | 397 | 53237519 |
Dehydration | 20.55 | 10.41 | 238 | 110912 | 168172 | 53069744 |
Drug eruption | 20.51 | 10.41 | 105 | 111045 | 24989 | 53212927 |
Nephrocalcinosis | 20.49 | 10.41 | 17 | 111133 | 1002 | 53236914 |
Negativism | 20.40 | 10.41 | 12 | 111138 | 404 | 53237512 |
Mitochondrial enzyme deficiency | 20.37 | 10.41 | 6 | 111144 | 30 | 53237886 |
Clonus | 20.36 | 10.41 | 34 | 111116 | 4257 | 53233659 |
Sinus congestion | 20.36 | 10.41 | 3 | 111147 | 14535 | 53223381 |
Inappropriate affect | 20.35 | 10.41 | 16 | 111134 | 873 | 53237043 |
Miosis | 20.28 | 10.41 | 45 | 111105 | 6957 | 53230959 |
Brain death | 20.18 | 10.41 | 28 | 111122 | 2980 | 53234936 |
Medication overuse headache | 20.06 | 10.41 | 14 | 111136 | 636 | 53237280 |
Drug withdrawal syndrome | 20.02 | 10.41 | 113 | 111037 | 27909 | 53210007 |
Food interaction | 20.00 | 10.41 | 14 | 111136 | 639 | 53237277 |
Sputum discoloured | 19.98 | 10.41 | 3 | 111147 | 14336 | 53223580 |
Drug screen false positive | 19.98 | 10.41 | 16 | 111134 | 897 | 53237019 |
Bursitis | 19.93 | 10.41 | 11 | 111139 | 22481 | 53215435 |
Mitochondrial cytopathy | 19.85 | 10.41 | 11 | 111139 | 330 | 53237586 |
Acquired macroglossia | 19.84 | 10.41 | 9 | 111141 | 174 | 53237742 |
Hiatus hernia | 19.83 | 10.41 | 8 | 111142 | 19612 | 53218304 |
Spinal stenosis | 19.80 | 10.41 | 3 | 111147 | 14238 | 53223678 |
Metastases to liver | 19.80 | 10.41 | 10 | 111140 | 21486 | 53216430 |
Pancreatitis acute | 19.80 | 10.41 | 107 | 111043 | 26002 | 53211914 |
Sexually inappropriate behaviour | 19.78 | 10.41 | 8 | 111142 | 115 | 53237801 |
Cross sensitivity reaction | 19.66 | 10.41 | 23 | 111127 | 2064 | 53235852 |
Flatulence | 19.62 | 10.41 | 22 | 111128 | 31495 | 53206421 |
Withdrawal syndrome | 19.60 | 10.41 | 86 | 111064 | 19215 | 53218701 |
Pneumocystis jirovecii pneumonia | 19.52 | 10.41 | 5 | 111145 | 16373 | 53221543 |
Ascites | 19.45 | 10.41 | 33 | 111117 | 39702 | 53198214 |
Macroglossia | 19.41 | 10.41 | 14 | 111136 | 670 | 53237246 |
Reduced facial expression | 19.38 | 10.41 | 21 | 111129 | 1733 | 53236183 |
Neglect of personal appearance | 19.36 | 10.41 | 8 | 111142 | 122 | 53237794 |
Increased appetite | 19.35 | 10.41 | 52 | 111098 | 9070 | 53228846 |
Neoplasm malignant | 19.32 | 10.41 | 15 | 111135 | 25586 | 53212330 |
Perseveration | 19.24 | 10.41 | 10 | 111140 | 263 | 53237653 |
Haemoptysis | 19.24 | 10.41 | 18 | 111132 | 28021 | 53209895 |
Epileptic psychosis | 19.18 | 10.41 | 6 | 111144 | 38 | 53237878 |
Clostridium difficile infection | 19.02 | 10.41 | 18 | 111132 | 27875 | 53210041 |
Congenital hepatomegaly | 18.98 | 10.41 | 5 | 111145 | 15 | 53237901 |
Pulmonary mass | 18.89 | 10.41 | 9 | 111141 | 19995 | 53217921 |
Influenza B virus test positive | 18.79 | 10.41 | 11 | 111139 | 367 | 53237549 |
Ultrasound ovary abnormal | 18.76 | 10.41 | 7 | 111143 | 80 | 53237836 |
Lipids | 18.74 | 10.41 | 5 | 111145 | 16 | 53237900 |
Congenital hearing disorder | 18.74 | 10.41 | 5 | 111145 | 16 | 53237900 |
Blood pressure fluctuation | 18.74 | 10.41 | 28 | 111122 | 35442 | 53202474 |
Hypothyroidism | 18.61 | 10.41 | 134 | 111016 | 35973 | 53201943 |
Attention-seeking behaviour | 18.60 | 10.41 | 7 | 111143 | 82 | 53237834 |
Device issue | 18.60 | 10.41 | 11 | 111139 | 21647 | 53216269 |
Congenital musculoskeletal anomaly | 18.57 | 10.41 | 12 | 111138 | 479 | 53237437 |
Blood insulin increased | 18.57 | 10.41 | 8 | 111142 | 136 | 53237780 |
Ear disorder | 18.57 | 10.41 | 29 | 111121 | 3433 | 53234483 |
Microstomia | 18.47 | 10.41 | 4 | 111146 | 3 | 53237913 |
Hip fracture | 18.39 | 10.41 | 19 | 111131 | 28238 | 53209678 |
Ulcer | 18.39 | 10.41 | 10 | 111140 | 20609 | 53217307 |
Prominent epicanthal folds | 18.31 | 10.41 | 6 | 111144 | 45 | 53237871 |
Urine amphetamine positive | 18.31 | 10.41 | 6 | 111144 | 45 | 53237871 |
Hypersomnia | 18.25 | 10.41 | 75 | 111075 | 16280 | 53221636 |
Cerebral ventricle dilatation | 18.20 | 10.41 | 16 | 111134 | 1021 | 53236895 |
Hypermetropia | 18.20 | 10.41 | 12 | 111138 | 496 | 53237420 |
Red blood cell sedimentation rate increased | 18.11 | 10.41 | 19 | 111131 | 28038 | 53209878 |
Coronary artery disease | 18.05 | 10.41 | 26 | 111124 | 33411 | 53204505 |
Transient aphasia | 17.97 | 10.41 | 6 | 111144 | 48 | 53237868 |
Limb discomfort | 17.96 | 10.41 | 16 | 111134 | 25506 | 53212410 |
Lipid metabolism disorder | 17.76 | 10.41 | 6 | 111144 | 50 | 53237866 |
Drug level changed | 17.71 | 10.41 | 8 | 111142 | 153 | 53237763 |
VIth nerve paralysis | 17.70 | 10.41 | 14 | 111136 | 771 | 53237145 |
Osmolar gap increased | 17.68 | 10.41 | 5 | 111145 | 21 | 53237895 |
Aspiration | 17.58 | 10.41 | 54 | 111096 | 10156 | 53227760 |
Thinking abnormal | 17.56 | 10.41 | 55 | 111095 | 10453 | 53227463 |
Product use issue | 17.52 | 10.41 | 196 | 110954 | 139388 | 53098528 |
Urine sodium increased | 17.48 | 10.41 | 7 | 111143 | 98 | 53237818 |
Eye pain | 17.48 | 10.41 | 23 | 111127 | 30702 | 53207214 |
Laryngeal stenosis | 17.37 | 10.41 | 14 | 111136 | 792 | 53237124 |
Kidney infection | 17.37 | 10.41 | 9 | 111141 | 19058 | 53218858 |
Acute generalised exanthematous pustulosis | 17.36 | 10.41 | 54 | 111096 | 10227 | 53227689 |
Osteoporosis | 17.34 | 10.41 | 45 | 111105 | 46415 | 53191501 |
Monocyte count decreased | 17.25 | 10.41 | 21 | 111129 | 1965 | 53235951 |
Microphthalmos | 17.25 | 10.41 | 8 | 111142 | 163 | 53237753 |
Brachydactyly | 17.23 | 10.41 | 7 | 111143 | 102 | 53237814 |
Benign congenital hypotonia | 17.16 | 10.41 | 6 | 111144 | 56 | 53237860 |
Cardiac disorder | 17.14 | 10.41 | 46 | 111104 | 46920 | 53190996 |
School refusal | 17.05 | 10.41 | 4 | 111146 | 6 | 53237910 |
Spina bifida occulta | 17.05 | 10.41 | 4 | 111146 | 6 | 53237910 |
Hostility | 17.05 | 10.41 | 19 | 111131 | 1618 | 53236298 |
Hyperkalaemia | 17.03 | 10.41 | 57 | 111093 | 54199 | 53183717 |
Nasal disorder | 16.94 | 10.41 | 23 | 111127 | 2398 | 53235518 |
Bladder sphincter atony | 16.90 | 10.41 | 8 | 111142 | 171 | 53237745 |
Incontinence | 16.84 | 10.41 | 55 | 111095 | 10688 | 53227228 |
Acute myocardial infarction | 16.82 | 10.41 | 27 | 111123 | 33208 | 53204708 |
Micrognathia | 16.80 | 10.41 | 9 | 111141 | 252 | 53237664 |
Cardiac steatosis | 16.79 | 10.41 | 6 | 111144 | 60 | 53237856 |
Haemorrhoids | 16.78 | 10.41 | 11 | 111139 | 20478 | 53217438 |
Diabetes mellitus | 16.77 | 10.41 | 179 | 110971 | 53720 | 53184196 |
Injection site urticaria | 16.76 | 10.41 | 3 | 111147 | 12604 | 53225312 |
Transfusion | 16.66 | 10.41 | 4 | 111146 | 13683 | 53224233 |
Faeces discoloured | 16.63 | 10.41 | 8 | 111142 | 17678 | 53220238 |
Head titubation | 16.49 | 10.41 | 13 | 111137 | 712 | 53237204 |
Musculoskeletal discomfort | 16.47 | 10.41 | 6 | 111144 | 15654 | 53222262 |
Device related infection | 16.38 | 10.41 | 14 | 111136 | 22772 | 53215144 |
Ketosis-prone diabetes mellitus | 16.33 | 10.41 | 4 | 111146 | 8 | 53237908 |
Dyscalculia | 16.28 | 10.41 | 6 | 111144 | 66 | 53237850 |
Impaired reasoning | 16.20 | 10.41 | 6 | 111144 | 67 | 53237849 |
Executive dysfunction | 16.14 | 10.41 | 7 | 111143 | 121 | 53237795 |
Renal hypoplasia | 16.07 | 10.41 | 5 | 111145 | 31 | 53237885 |
Asphyxia | 16.06 | 10.41 | 37 | 111113 | 5864 | 53232052 |
Parkinsonian gait | 16.05 | 10.41 | 11 | 111139 | 485 | 53237431 |
Electrocardiogram J wave abnormal | 16.01 | 10.41 | 4 | 111146 | 9 | 53237907 |
Sciatica | 16.00 | 10.41 | 13 | 111137 | 21680 | 53216236 |
Serositis | 15.99 | 10.41 | 12 | 111138 | 611 | 53237305 |
Tooth infection | 15.98 | 10.41 | 5 | 111145 | 14358 | 53223558 |
Hypoplastic left heart syndrome | 15.91 | 10.41 | 8 | 111142 | 196 | 53237720 |
Poisoning deliberate | 15.87 | 10.41 | 47 | 111103 | 8666 | 53229250 |
Colitis | 15.70 | 10.41 | 40 | 111110 | 41512 | 53196404 |
Hepatic cirrhosis | 15.70 | 10.41 | 9 | 111141 | 18013 | 53219903 |
Self-injurious ideation | 15.62 | 10.41 | 22 | 111128 | 2374 | 53235542 |
Anaemia macrocytic | 15.61 | 10.41 | 24 | 111126 | 2802 | 53235114 |
Drug dependence | 15.61 | 10.41 | 87 | 111063 | 21385 | 53216531 |
Lipids abnormal | 15.60 | 10.41 | 9 | 111141 | 292 | 53237624 |
Blister | 15.59 | 10.41 | 98 | 111052 | 78655 | 53159261 |
Pancreatic injury | 15.56 | 10.41 | 5 | 111145 | 35 | 53237881 |
Drug monitoring procedure incorrectly performed | 15.54 | 10.41 | 7 | 111143 | 133 | 53237783 |
Lip erosion | 15.53 | 10.41 | 14 | 111136 | 923 | 53236993 |
Tendonitis | 15.53 | 10.41 | 8 | 111142 | 16998 | 53220918 |
Carnitine palmitoyltransferase deficiency | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Diabetic encephalopathy | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Congenital myopia | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Alpers disease | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Cryptorchism | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
3-hydroxyacetyl-coenzyme A dehydrogenase deficiency | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Blood 1,25-dihydroxycholecalciferol decreased | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Congenital cutis laxa | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Mixed deafness | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Social (pragmatic) communication disorder | 15.53 | 10.41 | 3 | 111147 | 0 | 53237916 |
Chorea | 15.42 | 10.41 | 17 | 111133 | 1430 | 53236486 |
Prothrombin time shortened | 15.38 | 10.41 | 19 | 111131 | 1805 | 53236111 |
Erythema multiforme | 15.34 | 10.41 | 52 | 111098 | 10297 | 53227619 |
Memory impairment | 15.32 | 10.41 | 255 | 110895 | 84502 | 53153414 |
Heart rate irregular | 15.31 | 10.41 | 12 | 111138 | 20372 | 53217544 |
Drug level fluctuating | 15.28 | 10.41 | 10 | 111140 | 408 | 53237508 |
Oral herpes | 15.24 | 10.41 | 13 | 111137 | 21166 | 53216750 |
Diverticulum | 15.24 | 10.41 | 3 | 111147 | 11776 | 53226140 |
Spine malformation | 15.14 | 10.41 | 9 | 111141 | 309 | 53237607 |
Dysphoria | 15.07 | 10.41 | 34 | 111116 | 5315 | 53232601 |
Prescribed overdose | 15.03 | 10.41 | 63 | 111087 | 13796 | 53224120 |
Dysphagia | 14.91 | 10.41 | 253 | 110897 | 84144 | 53153772 |
Electrocardiogram T wave inversion | 14.88 | 10.41 | 27 | 111123 | 3612 | 53234304 |
Rectal haemorrhage | 14.86 | 10.41 | 41 | 111109 | 41440 | 53196476 |
Therapeutic product effective for unapproved indication | 14.85 | 10.41 | 6 | 111144 | 86 | 53237830 |
Ill-defined disorder | 14.80 | 10.41 | 53 | 111097 | 49391 | 53188525 |
Sneezing | 14.80 | 10.41 | 6 | 111144 | 14666 | 53223250 |
Crying | 14.75 | 10.41 | 88 | 111062 | 22174 | 53215742 |
Emotional disorder | 14.74 | 10.41 | 60 | 111090 | 12970 | 53224946 |
Syndactyly | 14.71 | 10.41 | 9 | 111141 | 326 | 53237590 |
Bacteraemia | 14.67 | 10.41 | 7 | 111143 | 15542 | 53222374 |
Incoherent | 14.65 | 10.41 | 31 | 111119 | 4641 | 53233275 |
Decreased activity | 14.64 | 10.41 | 34 | 111116 | 5417 | 53232499 |
Clonic convulsion | 14.63 | 10.41 | 12 | 111138 | 696 | 53237220 |
Tubo-ovarian abscess | 14.61 | 10.41 | 9 | 111141 | 330 | 53237586 |
Hepatomegaly | 14.61 | 10.41 | 56 | 111094 | 11775 | 53226141 |
Poor personal hygiene | 14.59 | 10.41 | 9 | 111141 | 331 | 53237585 |
Vascular encephalopathy | 14.51 | 10.41 | 10 | 111140 | 445 | 53237471 |
Congenital nipple anomaly | 14.50 | 10.41 | 4 | 111146 | 15 | 53237901 |
Live birth | 14.46 | 10.41 | 66 | 111084 | 14993 | 53222923 |
Urine calcium/creatinine ratio increased | 14.40 | 10.41 | 7 | 111143 | 159 | 53237757 |
Pulmonary valve stenosis congenital | 14.36 | 10.41 | 7 | 111143 | 160 | 53237756 |
Breast cancer metastatic | 14.31 | 10.41 | 7 | 111143 | 15321 | 53222595 |
Macular degeneration | 14.31 | 10.41 | 4 | 111146 | 12357 | 53225559 |
Heterophoria | 14.30 | 10.41 | 4 | 111146 | 16 | 53237900 |
Candida infection | 14.29 | 10.41 | 19 | 111131 | 25254 | 53212662 |
Intestinal strangulation | 14.26 | 10.41 | 6 | 111144 | 96 | 53237820 |
Grunting | 14.26 | 10.41 | 8 | 111142 | 246 | 53237670 |
Hospitalisation | 14.25 | 10.41 | 88 | 111062 | 70924 | 53166992 |
Seasonal allergy | 14.24 | 10.41 | 7 | 111143 | 15278 | 53222638 |
Joint effusion | 14.24 | 10.41 | 5 | 111145 | 13347 | 53224569 |
Joint range of motion decreased | 14.22 | 10.41 | 10 | 111140 | 17946 | 53219970 |
Intervertebral disc degeneration | 14.18 | 10.41 | 6 | 111144 | 14292 | 53223624 |
Plasmodium falciparum infection | 14.18 | 10.41 | 5 | 111145 | 48 | 53237868 |
Oral candidiasis | 14.16 | 10.41 | 11 | 111139 | 18762 | 53219154 |
Dyspepsia | 14.14 | 10.41 | 99 | 111051 | 77501 | 53160415 |
Opisthotonus | 14.14 | 10.41 | 9 | 111141 | 350 | 53237566 |
Acidosis | 14.13 | 10.41 | 54 | 111096 | 11338 | 53226578 |
Electrocardiogram QRS complex shortened | 14.10 | 10.41 | 10 | 111140 | 466 | 53237450 |
Hypoproteinaemia | 14.10 | 10.41 | 19 | 111131 | 1967 | 53235949 |
Glaucoma | 14.10 | 10.41 | 9 | 111141 | 16994 | 53220922 |
Amniocentesis abnormal | 14.09 | 10.41 | 6 | 111144 | 99 | 53237817 |
Liver function test increased | 14.08 | 10.41 | 21 | 111129 | 26607 | 53211309 |
Autonomic nervous system imbalance | 14.04 | 10.41 | 22 | 111128 | 2612 | 53235304 |
Simple partial seizures | 14.03 | 10.41 | 11 | 111139 | 598 | 53237318 |
Sinus disorder | 13.98 | 10.41 | 11 | 111139 | 18643 | 53219273 |
Rib fracture | 13.93 | 10.41 | 13 | 111137 | 20265 | 53217651 |
Ebstein's anomaly | 13.92 | 10.41 | 4 | 111146 | 18 | 53237898 |
Colitis ulcerative | 13.89 | 10.41 | 14 | 111136 | 21047 | 53216869 |
Gliosis | 13.86 | 10.41 | 8 | 111142 | 260 | 53237656 |
Blood triglycerides increased | 13.84 | 10.41 | 57 | 111093 | 12384 | 53225532 |
False positive investigation result | 13.84 | 10.41 | 11 | 111139 | 610 | 53237306 |
Dry eye | 13.81 | 10.41 | 31 | 111119 | 33613 | 53204303 |
Mucosal erosion | 13.79 | 10.41 | 16 | 111134 | 1423 | 53236493 |
Shock | 13.78 | 10.41 | 89 | 111061 | 23050 | 53214866 |
Copper deficiency | 13.74 | 10.41 | 5 | 111145 | 53 | 53237863 |
Immunodeficiency | 13.73 | 10.41 | 7 | 111143 | 14960 | 53222956 |
Withdrawal catatonia | 13.65 | 10.41 | 5 | 111145 | 54 | 53237862 |
Congenital laryngeal stridor | 13.65 | 10.41 | 5 | 111145 | 54 | 53237862 |
Septic shock | 13.61 | 10.41 | 75 | 111075 | 62154 | 53175762 |
Gaucher's disease | 13.58 | 10.41 | 4 | 111146 | 20 | 53237896 |
Deja vu | 13.57 | 10.41 | 5 | 111145 | 55 | 53237861 |
Illness | 13.54 | 10.41 | 16 | 111134 | 22380 | 53215536 |
Extensor plantar response | 13.53 | 10.41 | 15 | 111135 | 1270 | 53236646 |
Suspected suicide attempt | 13.51 | 10.41 | 6 | 111144 | 110 | 53237806 |
Rasmussen encephalitis | 13.45 | 10.41 | 3 | 111147 | 3 | 53237913 |
Congenital inguinal hernia | 13.45 | 10.41 | 3 | 111147 | 3 | 53237913 |
Blood pyruvic acid increased | 13.45 | 10.41 | 3 | 111147 | 3 | 53237913 |
Asocial behaviour | 13.45 | 10.41 | 3 | 111147 | 3 | 53237913 |
Tachypnoea | 13.42 | 10.41 | 67 | 111083 | 15787 | 53222129 |
Infusion site pain | 13.38 | 10.41 | 4 | 111146 | 11829 | 53226087 |
Medication error | 13.36 | 10.41 | 125 | 111025 | 36240 | 53201676 |
Procedural pain | 13.33 | 10.41 | 7 | 111143 | 14710 | 53223206 |
Sinus bradycardia | 13.29 | 10.41 | 63 | 111087 | 14538 | 53223378 |
Coma hepatic | 13.26 | 10.41 | 11 | 111139 | 648 | 53237268 |
Gallbladder disorder | 13.26 | 10.41 | 11 | 111139 | 18154 | 53219762 |
Glassy eyes | 13.26 | 10.41 | 5 | 111145 | 59 | 53237857 |
Mental disability | 13.22 | 10.41 | 6 | 111144 | 116 | 53237800 |
Intestinal ischaemia | 13.22 | 10.41 | 40 | 111110 | 7462 | 53230454 |
Hyperphagia | 13.20 | 10.41 | 17 | 111133 | 1684 | 53236232 |
Skin discolouration | 13.20 | 10.41 | 34 | 111116 | 35158 | 53202758 |
Dysphonia | 13.20 | 10.41 | 44 | 111106 | 41894 | 53196022 |
Thought blocking | 13.18 | 10.41 | 6 | 111144 | 117 | 53237799 |
Activated partial thromboplastin time abnormal | 13.13 | 10.41 | 6 | 111144 | 118 | 53237798 |
Rash morbilliform | 13.07 | 10.41 | 24 | 111126 | 3239 | 53234677 |
Posturing | 13.07 | 10.41 | 10 | 111140 | 524 | 53237392 |
Sudden death | 13.06 | 10.41 | 49 | 111101 | 10199 | 53227717 |
Drug ineffective | 13.04 | 10.41 | 1916 | 109234 | 815329 | 52422587 |
Gastric disorder | 13.04 | 10.41 | 27 | 111123 | 30138 | 53207778 |
Saccadic eye movement | 13.03 | 10.41 | 5 | 111145 | 62 | 53237854 |
Childhood asthma | 13.03 | 10.41 | 5 | 111145 | 62 | 53237854 |
Accidental poisoning | 13.00 | 10.41 | 11 | 111139 | 666 | 53237250 |
Cortical visual impairment | 12.99 | 10.41 | 3 | 111147 | 4 | 53237912 |
Quadriparesis | 12.99 | 10.41 | 18 | 111132 | 1913 | 53236003 |
Amino acid level increased | 12.95 | 10.41 | 8 | 111142 | 295 | 53237621 |
Bradypnoea | 12.90 | 10.41 | 24 | 111126 | 3273 | 53234643 |
Blood urea decreased | 12.85 | 10.41 | 20 | 111130 | 2360 | 53235556 |
Therapeutic product ineffective for unapproved indication | 12.85 | 10.41 | 7 | 111143 | 203 | 53237713 |
Idiosyncratic drug reaction | 12.74 | 10.41 | 12 | 111138 | 837 | 53237079 |
Coma acidotic | 12.69 | 10.41 | 6 | 111144 | 128 | 53237788 |
Acute myeloid leukaemia | 12.67 | 10.41 | 10 | 111140 | 16922 | 53220994 |
Device difficult to use | 12.66 | 10.41 | 3 | 111147 | 10356 | 53227560 |
Hypoglycaemia neonatal | 12.66 | 10.41 | 13 | 111137 | 1008 | 53236908 |
Cerebral palsy | 12.64 | 10.41 | 6 | 111144 | 129 | 53237787 |
Lung disorder | 12.62 | 10.41 | 54 | 111096 | 47825 | 53190091 |
Epileptic aura | 12.55 | 10.41 | 5 | 111145 | 69 | 53237847 |
Generalised anxiety disorder | 12.51 | 10.41 | 18 | 111132 | 1982 | 53235934 |
Oedema peripheral | 12.47 | 10.41 | 266 | 110884 | 170521 | 53067395 |
High-pitched crying | 12.44 | 10.41 | 4 | 111146 | 28 | 53237888 |
Otitis media | 12.44 | 10.41 | 29 | 111121 | 4632 | 53233284 |
Tooth disorder | 12.40 | 10.41 | 21 | 111129 | 25291 | 53212625 |
Injection site warmth | 12.38 | 10.41 | 7 | 111143 | 14121 | 53223795 |
Homicidal ideation | 12.34 | 10.41 | 17 | 111133 | 1797 | 53236119 |
Postictal state | 12.29 | 10.41 | 13 | 111137 | 1043 | 53236873 |
Maternal exposure during breast feeding | 12.29 | 10.41 | 24 | 111126 | 3393 | 53234523 |
Disorganised speech | 12.28 | 10.41 | 13 | 111137 | 1044 | 53236872 |
Cell death | 12.27 | 10.41 | 20 | 111130 | 2455 | 53235461 |
Congenital neurological disorder | 12.24 | 10.41 | 3 | 111147 | 6 | 53237910 |
Regressive behaviour | 12.23 | 10.41 | 5 | 111145 | 74 | 53237842 |
Blood sodium increased | 12.22 | 10.41 | 21 | 111129 | 2691 | 53235225 |
Laboratory test abnormal | 12.19 | 10.41 | 20 | 111130 | 24389 | 53213527 |
Upper gastrointestinal haemorrhage | 12.18 | 10.41 | 11 | 111139 | 17419 | 53220497 |
Nodule | 12.18 | 10.41 | 11 | 111139 | 17418 | 53220498 |
Blood citric acid increased | 12.05 | 10.41 | 5 | 111145 | 77 | 53237839 |
Inhibitory drug interaction | 12.03 | 10.41 | 19 | 111131 | 2271 | 53235645 |
Hyporesponsive to stimuli | 12.01 | 10.41 | 13 | 111137 | 1071 | 53236845 |
Spinal fracture | 12.01 | 10.41 | 10 | 111140 | 16475 | 53221441 |
Ligament laxity | 12.00 | 10.41 | 6 | 111144 | 145 | 53237771 |
Malignant catatonia | 11.98 | 10.41 | 4 | 111146 | 32 | 53237884 |
Joint hyperextension | 11.97 | 10.41 | 7 | 111143 | 233 | 53237683 |
Anotia | 11.93 | 10.41 | 3 | 111147 | 7 | 53237909 |
Fine motor delay | 11.93 | 10.41 | 6 | 111144 | 147 | 53237769 |
Choreoathetosis | 11.93 | 10.41 | 9 | 111141 | 462 | 53237454 |
Intervertebral disc protrusion | 11.91 | 10.41 | 17 | 111133 | 21928 | 53215988 |
Pancreatitis haemorrhagic | 11.89 | 10.41 | 8 | 111142 | 342 | 53237574 |
Respiratory tract congestion | 11.89 | 10.41 | 8 | 111142 | 14691 | 53223225 |
Congenital eye disorder | 11.87 | 10.41 | 4 | 111146 | 33 | 53237883 |
Anaphylactic shock | 11.84 | 10.41 | 17 | 111133 | 21876 | 53216040 |
Myoglobinuria | 11.79 | 10.41 | 7 | 111143 | 240 | 53237676 |
Brain stem syndrome | 11.77 | 10.41 | 8 | 111142 | 348 | 53237568 |
Therapeutic response changed | 11.77 | 10.41 | 12 | 111138 | 923 | 53236993 |
Congenital hypothyroidism | 11.76 | 10.41 | 7 | 111143 | 241 | 53237675 |
Systemic inflammatory response syndrome | 11.74 | 10.41 | 32 | 111118 | 5628 | 53232288 |
Toothache | 11.71 | 10.41 | 12 | 111138 | 17902 | 53220014 |
Presyncope | 11.71 | 10.41 | 23 | 111127 | 26171 | 53211745 |
Premature baby | 11.69 | 10.41 | 76 | 111074 | 19725 | 53218191 |
Tooth development disorder | 11.67 | 10.41 | 4 | 111146 | 35 | 53237881 |
Rash pruritic | 11.65 | 10.41 | 59 | 111091 | 49951 | 53187965 |
Electrocardiogram J wave | 11.65 | 10.41 | 3 | 111147 | 8 | 53237908 |
Magnetic resonance imaging head abnormal | 11.61 | 10.41 | 17 | 111133 | 1901 | 53236015 |
Malignant melanoma | 11.60 | 10.41 | 4 | 111146 | 10798 | 53227118 |
Hepatic steatosis | 11.60 | 10.41 | 94 | 111056 | 26165 | 53211751 |
Eye swelling | 11.58 | 10.41 | 17 | 111133 | 21677 | 53216239 |
Haemorrhage | 11.56 | 10.41 | 72 | 111078 | 57915 | 53180001 |
Poverty of speech | 11.55 | 10.41 | 8 | 111142 | 359 | 53237557 |
Tympanic membrane disorder | 11.54 | 10.41 | 6 | 111144 | 158 | 53237758 |
Slow response to stimuli | 11.51 | 10.41 | 12 | 111138 | 947 | 53236969 |
Viral infection | 11.51 | 10.41 | 32 | 111118 | 32263 | 53205653 |
Congenital tracheomalacia | 11.47 | 10.41 | 4 | 111146 | 37 | 53237879 |
Developmental coordination disorder | 11.47 | 10.41 | 4 | 111146 | 37 | 53237879 |
Metastases to lung | 11.46 | 10.41 | 5 | 111145 | 11699 | 53226217 |
Acne | 11.44 | 10.41 | 17 | 111133 | 21569 | 53216347 |
Blood bicarbonate increased | 11.42 | 10.41 | 11 | 111139 | 789 | 53237127 |
Ageusia | 11.42 | 10.41 | 6 | 111144 | 12608 | 53225308 |
Alanine aminotransferase increased | 11.41 | 10.41 | 269 | 110881 | 94826 | 53143090 |
Congenital gastric anomaly | 11.39 | 10.41 | 3 | 111147 | 9 | 53237907 |
Congenital floppy infant | 11.39 | 10.41 | 3 | 111147 | 9 | 53237907 |
Head circumference abnormal | 11.39 | 10.41 | 3 | 111147 | 9 | 53237907 |
Post-anoxic myoclonus | 11.38 | 10.41 | 4 | 111146 | 38 | 53237878 |
Postictal paralysis | 11.34 | 10.41 | 5 | 111145 | 90 | 53237826 |
Creatinine renal clearance decreased | 11.34 | 10.41 | 4 | 111146 | 10647 | 53227269 |
Osteonecrosis | 11.31 | 10.41 | 24 | 111126 | 26551 | 53211365 |
Sinus tachycardia | 11.30 | 10.41 | 86 | 111064 | 23486 | 53214430 |
Thermal burn | 11.27 | 10.41 | 30 | 111120 | 5203 | 53232713 |
Mobility decreased | 11.26 | 10.41 | 103 | 111047 | 76168 | 53161748 |
Hydrocephalus | 11.26 | 10.41 | 30 | 111120 | 5206 | 53232710 |
Knee deformity | 11.26 | 10.41 | 12 | 111138 | 972 | 53236944 |
Blood osmolarity increased | 11.17 | 10.41 | 6 | 111144 | 169 | 53237747 |
Intention tremor | 11.17 | 10.41 | 8 | 111142 | 379 | 53237537 |
Neonatal disorder | 11.16 | 10.41 | 10 | 111140 | 654 | 53237262 |
Maternal drugs affecting foetus | 11.15 | 10.41 | 31 | 111119 | 5515 | 53232401 |
Faecal vomiting | 11.11 | 10.41 | 10 | 111140 | 658 | 53237258 |
Rotator cuff syndrome | 11.09 | 10.41 | 6 | 111144 | 12399 | 53225517 |
Skin disorder | 11.08 | 10.41 | 22 | 111128 | 24936 | 53212980 |
Gout | 11.08 | 10.41 | 6 | 111144 | 12393 | 53225523 |
Reproductive tract disorder | 11.07 | 10.41 | 6 | 111144 | 172 | 53237744 |
Oppositional defiant disorder | 11.02 | 10.41 | 4 | 111146 | 42 | 53237874 |
Aura | 11.01 | 10.41 | 12 | 111138 | 997 | 53236919 |
Exostosis | 11.00 | 10.41 | 5 | 111145 | 11419 | 53226497 |
Deep vein thrombosis | 10.97 | 10.41 | 115 | 111035 | 82798 | 53155118 |
Cleft uvula | 10.93 | 10.41 | 3 | 111147 | 11 | 53237905 |
Congenital oesophageal anomaly | 10.93 | 10.41 | 3 | 111147 | 11 | 53237905 |
Procalcitonin increased | 10.87 | 10.41 | 11 | 111139 | 838 | 53237078 |
Antidepressant drug level increased | 10.82 | 10.41 | 7 | 111143 | 280 | 53237636 |
Eosinophilic myocarditis | 10.79 | 10.41 | 8 | 111142 | 400 | 53237516 |
Encapsulating peritoneal sclerosis | 10.73 | 10.41 | 8 | 111142 | 403 | 53237513 |
Congenital nail disorder | 10.73 | 10.41 | 5 | 111145 | 103 | 53237813 |
Toe walking | 10.72 | 10.41 | 3 | 111147 | 12 | 53237904 |
Type 2 diabetes mellitus | 10.72 | 10.41 | 107 | 111043 | 31563 | 53206353 |
Persistent left superior vena cava | 10.70 | 10.41 | 4 | 111146 | 46 | 53237870 |
Hernia | 10.67 | 10.41 | 4 | 111146 | 10256 | 53227660 |
Hyperaldosteronism | 10.67 | 10.41 | 7 | 111143 | 287 | 53237629 |
Delusional disorder, unspecified type | 10.66 | 10.41 | 8 | 111142 | 407 | 53237509 |
Tongue biting | 10.62 | 10.41 | 14 | 111136 | 1419 | 53236497 |
Therapy interrupted | 10.60 | 10.41 | 15 | 111135 | 19421 | 53218495 |
Delusion of reference | 10.60 | 10.41 | 5 | 111145 | 106 | 53237810 |
Glioblastoma multiforme | 10.58 | 10.41 | 11 | 111139 | 865 | 53237051 |
Febrile convulsion | 10.56 | 10.41 | 8 | 111142 | 413 | 53237503 |
Scar excision | 10.54 | 10.41 | 4 | 111146 | 48 | 53237868 |
Neutrophilia | 10.51 | 10.41 | 23 | 111127 | 3522 | 53234394 |
Transplant rejection | 10.49 | 10.41 | 4 | 111146 | 10147 | 53227769 |
Histiocytic necrotising lymphadenitis | 10.47 | 10.41 | 4 | 111146 | 49 | 53237867 |
Thyroglobulin increased | 10.47 | 10.41 | 4 | 111146 | 49 | 53237867 |
Nikolsky's sign | 10.43 | 10.41 | 5 | 111145 | 110 | 53237806 |
Burning sensation | 10.43 | 10.41 | 58 | 111092 | 47955 | 53189961 |
Carpal tunnel syndrome | 10.42 | 10.41 | 13 | 111137 | 17754 | 53220162 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Seizure | 1855.60 | 11.48 | 2110 | 119911 | 101744 | 32289761 |
Hyperammonaemia | 1176.59 | 11.48 | 532 | 121489 | 5437 | 32386068 |
Foetal anticonvulsant syndrome | 913.50 | 11.48 | 279 | 121742 | 772 | 32390733 |
Epilepsy | 888.03 | 11.48 | 705 | 121316 | 21404 | 32370101 |
Drug interaction | 872.17 | 11.48 | 2270 | 119751 | 215915 | 32175590 |
Dysmorphism | 829.59 | 11.48 | 333 | 121688 | 2460 | 32389045 |
Aggression | 788.44 | 11.48 | 851 | 121170 | 38538 | 32352967 |
Hyperammonaemic encephalopathy | 742.43 | 11.48 | 283 | 121738 | 1788 | 32389717 |
Neuroleptic malignant syndrome | 726.41 | 11.48 | 569 | 121452 | 16926 | 32374579 |
Status epilepticus | 706.18 | 11.48 | 482 | 121539 | 11524 | 32379981 |
Foetal exposure during pregnancy | 563.81 | 11.48 | 734 | 121287 | 40567 | 32350938 |
Autism spectrum disorder | 536.90 | 11.48 | 218 | 121803 | 1664 | 32389841 |
Somnolence | 521.02 | 11.48 | 1181 | 120840 | 102616 | 32288889 |
Speech disorder developmental | 462.35 | 11.48 | 192 | 121829 | 1562 | 32389943 |
Generalised tonic-clonic seizure | 439.34 | 11.48 | 461 | 121560 | 20178 | 32371327 |
Dyspnoea | 421.58 | 11.48 | 444 | 121577 | 361601 | 32029904 |
Mania | 414.30 | 11.48 | 320 | 121701 | 9312 | 32382193 |
Ammonia increased | 392.05 | 11.48 | 231 | 121790 | 4233 | 32387272 |
Developmental delay | 390.97 | 11.48 | 193 | 121828 | 2435 | 32389070 |
Abnormal behaviour | 382.44 | 11.48 | 484 | 121537 | 25982 | 32365523 |
Diarrhoea | 367.54 | 11.48 | 501 | 121520 | 364301 | 32027204 |
Sopor | 362.63 | 11.48 | 322 | 121699 | 11427 | 32380078 |
Agitation | 359.46 | 11.48 | 714 | 121307 | 56522 | 32334983 |
Psychotic disorder | 353.43 | 11.48 | 434 | 121587 | 22586 | 32368919 |
Sedation | 331.94 | 11.48 | 378 | 121643 | 18148 | 32373357 |
Psychomotor retardation | 324.51 | 11.48 | 177 | 121844 | 2778 | 32388727 |
Granulocytopenia | 321.42 | 11.48 | 235 | 121786 | 6280 | 32385225 |
Extrapyramidal disorder | 320.27 | 11.48 | 302 | 121719 | 11593 | 32379912 |
Parkinsonism | 320.16 | 11.48 | 253 | 121768 | 7616 | 32383889 |
Learning disorder | 317.72 | 11.48 | 120 | 121901 | 736 | 32390769 |
Intellectual disability | 305.50 | 11.48 | 127 | 121894 | 1036 | 32390469 |
Cognitive disorder | 299.72 | 11.48 | 425 | 121596 | 25469 | 32366036 |
Death | 284.43 | 11.48 | 636 | 121385 | 381881 | 32009624 |
Febrile neutropenia | 272.68 | 11.48 | 58 | 121963 | 119508 | 32271997 |
Toxicity to various agents | 268.85 | 11.48 | 1349 | 120672 | 176692 | 32214813 |
Language disorder | 257.50 | 11.48 | 132 | 121889 | 1813 | 32389692 |
Arthralgia | 256.76 | 11.48 | 118 | 121903 | 148330 | 32243175 |
Coma | 254.80 | 11.48 | 521 | 121500 | 42091 | 32349414 |
Schizophrenia | 250.81 | 11.48 | 244 | 121777 | 9740 | 32381765 |
Acute kidney injury | 244.09 | 11.48 | 457 | 121564 | 293011 | 32098494 |
Petit mal epilepsy | 243.47 | 11.48 | 146 | 121875 | 2766 | 32388739 |
Congenital nose malformation | 235.71 | 11.48 | 67 | 121954 | 130 | 32391375 |
Depression | 235.50 | 11.48 | 850 | 121171 | 96210 | 32295295 |
Nausea | 227.29 | 11.48 | 547 | 121474 | 320302 | 32071203 |
Fatigue | 224.69 | 11.48 | 629 | 121392 | 350072 | 32041433 |
Hypospadias | 224.33 | 11.48 | 140 | 121881 | 2857 | 32388648 |
Antipsychotic drug level increased | 224.31 | 11.48 | 149 | 121872 | 3397 | 32388108 |
Salivary hypersecretion | 222.80 | 11.48 | 208 | 121813 | 7880 | 32383625 |
Intentional overdose | 221.31 | 11.48 | 485 | 121536 | 41116 | 32350389 |
Psychomotor skills impaired | 218.41 | 11.48 | 129 | 121892 | 2374 | 32389131 |
Irritability | 216.50 | 11.48 | 356 | 121665 | 24298 | 32367207 |
Intentional self-injury | 216.43 | 11.48 | 264 | 121757 | 13636 | 32377869 |
Attention deficit hyperactivity disorder | 214.24 | 11.48 | 122 | 121899 | 2090 | 32389415 |
Behaviour disorder | 214.20 | 11.48 | 146 | 121875 | 3478 | 32388027 |
Disturbance in attention | 214.02 | 11.48 | 347 | 121674 | 23406 | 32368099 |
Anaemia | 207.02 | 11.48 | 325 | 121696 | 223299 | 32168206 |
Myocardial infarction | 206.47 | 11.48 | 107 | 121914 | 125569 | 32265936 |
Drug level decreased | 205.54 | 11.48 | 180 | 121841 | 6266 | 32385239 |
Drug level increased | 199.79 | 11.48 | 307 | 121714 | 19773 | 32371732 |
Atrial fibrillation | 195.24 | 11.48 | 97 | 121924 | 116607 | 32274898 |
Psychomotor hyperactivity | 194.23 | 11.48 | 203 | 121818 | 8836 | 32382669 |
Mental impairment | 192.52 | 11.48 | 212 | 121809 | 9800 | 32381705 |
Ataxia | 190.33 | 11.48 | 237 | 121784 | 12504 | 32379001 |
Akathisia | 182.69 | 11.48 | 175 | 121846 | 6850 | 32384655 |
Pain | 181.79 | 11.48 | 264 | 121757 | 187292 | 32204213 |
Suicide attempt | 181.31 | 11.48 | 426 | 121595 | 37818 | 32353687 |
Overdose | 180.16 | 11.48 | 725 | 121296 | 86352 | 32305153 |
Cardiac failure congestive | 179.92 | 11.48 | 48 | 121973 | 84804 | 32306701 |
Dysgraphia | 179.23 | 11.48 | 104 | 121917 | 1849 | 32389656 |
Speech disorder | 178.66 | 11.48 | 339 | 121682 | 25914 | 32365591 |
Tremor | 178.06 | 11.48 | 689 | 121332 | 80588 | 32310917 |
Hypertelorism | 175.72 | 11.48 | 69 | 121952 | 477 | 32391028 |
Plasma cell myeloma | 175.66 | 11.48 | 10 | 122011 | 57604 | 32333901 |
Electroencephalogram abnormal | 167.20 | 11.48 | 110 | 121911 | 2466 | 32389039 |
Blood creatine phosphokinase increased | 167.10 | 11.48 | 460 | 121561 | 45016 | 32346489 |
Gastrointestinal haemorrhage | 163.10 | 11.48 | 61 | 121960 | 86821 | 32304684 |
Pneumonia | 162.03 | 11.48 | 735 | 121286 | 354517 | 32036988 |
Multiple-drug resistance | 161.39 | 11.48 | 125 | 121896 | 3650 | 32387855 |
Anticonvulsant drug level increased | 160.27 | 11.48 | 89 | 121932 | 1449 | 32390056 |
Depressed level of consciousness | 159.94 | 11.48 | 423 | 121598 | 40424 | 32351081 |
Neuropathy peripheral | 158.63 | 11.48 | 46 | 121975 | 76936 | 32314569 |
Hallucination, auditory | 158.57 | 11.48 | 195 | 121826 | 10155 | 32381350 |
Partial seizures | 157.24 | 11.48 | 128 | 121893 | 4022 | 32387483 |
Pain in extremity | 156.31 | 11.48 | 130 | 121891 | 118771 | 32272734 |
Dystonia | 152.93 | 11.48 | 194 | 121827 | 10429 | 32381076 |
Antipsychotic drug level below therapeutic | 152.48 | 11.48 | 94 | 121927 | 1875 | 32389630 |
Anticonvulsant drug level decreased | 147.29 | 11.48 | 73 | 121948 | 929 | 32390576 |
Catatonia | 147.17 | 11.48 | 130 | 121891 | 4578 | 32386927 |
Product residue present | 146.63 | 11.48 | 105 | 121916 | 2713 | 32388792 |
Delusion | 145.54 | 11.48 | 211 | 121810 | 12897 | 32378608 |
Astigmatism | 142.27 | 11.48 | 71 | 121950 | 918 | 32390587 |
Hypotonia | 141.31 | 11.48 | 159 | 121862 | 7528 | 32383977 |
Muscle rigidity | 138.94 | 11.48 | 190 | 121831 | 10996 | 32380509 |
Product substitution issue | 136.84 | 11.48 | 182 | 121839 | 10254 | 32381251 |
Interstitial lung disease | 135.46 | 11.48 | 38 | 121983 | 64963 | 32326542 |
Motor developmental delay | 135.23 | 11.48 | 57 | 121964 | 483 | 32391022 |
Malignant neoplasm progression | 131.58 | 11.48 | 65 | 121956 | 78431 | 32313074 |
Neurodevelopmental disorder | 131.23 | 11.48 | 42 | 121979 | 142 | 32391363 |
Tardive dyskinesia | 131.15 | 11.48 | 131 | 121890 | 5400 | 32386105 |
Enuresis | 129.68 | 11.48 | 87 | 121934 | 2017 | 32389488 |
Schizoaffective disorder | 128.99 | 11.48 | 73 | 121948 | 1235 | 32390270 |
Wrong patient received product | 128.71 | 11.48 | 92 | 121929 | 2370 | 32389135 |
Disease progression | 128.32 | 11.48 | 84 | 121937 | 86778 | 32304727 |
Lip disorder | 128.02 | 11.48 | 51 | 121970 | 368 | 32391137 |
Asthenia | 123.01 | 11.48 | 463 | 121558 | 235481 | 32156024 |
Euphoric mood | 122.47 | 11.48 | 123 | 121898 | 5104 | 32386401 |
Bipolar disorder | 122.38 | 11.48 | 108 | 121913 | 3798 | 32387707 |
Paranoia | 121.59 | 11.48 | 175 | 121846 | 10624 | 32380881 |
Renal failure | 120.88 | 11.48 | 199 | 121822 | 134279 | 32257226 |
Delirium | 120.78 | 11.48 | 402 | 121619 | 43644 | 32347861 |
Dyspraxia | 120.59 | 11.48 | 46 | 121975 | 291 | 32391214 |
Encephalopathy | 120.38 | 11.48 | 341 | 121680 | 33916 | 32357589 |
Dyskinesia | 118.52 | 11.48 | 269 | 121752 | 23334 | 32368171 |
Mental disorder | 118.27 | 11.48 | 203 | 121818 | 14345 | 32377160 |
Congenital oral malformation | 116.49 | 11.48 | 26 | 121995 | 3 | 32391502 |
Myopia | 116.40 | 11.48 | 60 | 121961 | 834 | 32390671 |
Dysarthria | 116.19 | 11.48 | 330 | 121691 | 32871 | 32358634 |
Joint swelling | 116.00 | 11.48 | 26 | 121995 | 51709 | 32339796 |
Chest pain | 115.04 | 11.48 | 180 | 121841 | 123957 | 32267548 |
Treatment noncompliance | 115.01 | 11.48 | 290 | 121731 | 26912 | 32364593 |
Foot deformity | 114.66 | 11.48 | 106 | 121915 | 3964 | 32387541 |
Cough | 114.30 | 11.48 | 217 | 121804 | 138600 | 32252905 |
Peripheral swelling | 113.93 | 11.48 | 57 | 121964 | 68288 | 32323217 |
Skull malformation | 112.88 | 11.48 | 47 | 121974 | 385 | 32391120 |
Priapism | 112.47 | 11.48 | 115 | 121906 | 4876 | 32386629 |
Talipes | 111.80 | 11.48 | 76 | 121945 | 1802 | 32389703 |
Cryptorchism | 109.77 | 11.48 | 76 | 121945 | 1858 | 32389647 |
Drug reaction with eosinophilia and systemic symptoms | 108.95 | 11.48 | 318 | 121703 | 32167 | 32359338 |
Sudden unexplained death in epilepsy | 108.86 | 11.48 | 47 | 121974 | 425 | 32391080 |
Myocarditis | 106.66 | 11.48 | 171 | 121850 | 11419 | 32380086 |
Focal dyscognitive seizures | 106.35 | 11.48 | 65 | 121956 | 1276 | 32390229 |
Myoclonic epilepsy | 105.77 | 11.48 | 58 | 121963 | 920 | 32390585 |
Hypotonia neonatal | 105.63 | 11.48 | 62 | 121959 | 1127 | 32390378 |
Strabismus | 105.30 | 11.48 | 66 | 121955 | 1357 | 32390148 |
Altered state of consciousness | 105.27 | 11.48 | 246 | 121775 | 21751 | 32369754 |
Pruritus | 105.24 | 11.48 | 202 | 121819 | 128500 | 32263005 |
Thrombosis | 104.60 | 11.48 | 22 | 121999 | 45732 | 32345773 |
Limb malformation | 104.15 | 11.48 | 47 | 121974 | 477 | 32391028 |
Infusion related reaction | 104.09 | 11.48 | 22 | 121999 | 45577 | 32345928 |
Restlessness | 102.84 | 11.48 | 263 | 121758 | 24618 | 32366887 |
Obsessive-compulsive disorder | 102.77 | 11.48 | 109 | 121912 | 4825 | 32386680 |
Learning disability | 102.73 | 11.48 | 39 | 121982 | 243 | 32391262 |
Bradyphrenia | 101.31 | 11.48 | 105 | 121916 | 4524 | 32386981 |
Back pain | 101.02 | 11.48 | 163 | 121858 | 110890 | 32280615 |
Drug level below therapeutic | 100.65 | 11.48 | 100 | 121921 | 4095 | 32387410 |
Anticonvulsant drug level below therapeutic | 100.45 | 11.48 | 49 | 121972 | 601 | 32390904 |
Cardiac failure | 99.98 | 11.48 | 118 | 121903 | 91555 | 32299950 |
Thinking abnormal | 99.24 | 11.48 | 114 | 121907 | 5521 | 32385984 |
Coronary artery disease | 98.23 | 11.48 | 32 | 121989 | 49674 | 32341831 |
Disinhibition | 97.00 | 11.48 | 81 | 121940 | 2639 | 32388866 |
Communication disorder | 96.43 | 11.48 | 79 | 121942 | 2505 | 32389000 |
Oedema peripheral | 95.96 | 11.48 | 176 | 121845 | 113915 | 32277590 |
Myalgia | 95.81 | 11.48 | 98 | 121923 | 81132 | 32310373 |
Joint laxity | 95.70 | 11.48 | 37 | 121984 | 244 | 32391261 |
Congenital foot malformation | 95.06 | 11.48 | 37 | 121984 | 249 | 32391256 |
Low set ears | 95.03 | 11.48 | 42 | 121979 | 404 | 32391101 |
Myoclonus | 94.71 | 11.48 | 185 | 121836 | 14444 | 32377061 |
Suicidal ideation | 94.29 | 11.48 | 336 | 121685 | 37747 | 32353758 |
Psoriasis | 94.18 | 11.48 | 28 | 121993 | 46095 | 32345410 |
Abdominal pain | 93.26 | 11.48 | 271 | 121750 | 149258 | 32242247 |
Coordination abnormal | 92.31 | 11.48 | 129 | 121892 | 7619 | 32383886 |
Acute myocardial infarction | 91.90 | 11.48 | 46 | 121975 | 55103 | 32336402 |
Disorientation | 90.67 | 11.48 | 304 | 121717 | 33121 | 32358384 |
Fanconi syndrome | 90.55 | 11.48 | 66 | 121955 | 1754 | 32389751 |
Sepsis | 90.47 | 11.48 | 300 | 121721 | 158534 | 32232971 |
Drooling | 89.28 | 11.48 | 84 | 121937 | 3213 | 32388292 |
Educational problem | 88.93 | 11.48 | 41 | 121980 | 439 | 32391066 |
Dizziness | 86.35 | 11.48 | 449 | 121572 | 209169 | 32182336 |
Anticonvulsant drug level above therapeutic | 86.33 | 11.48 | 41 | 121980 | 472 | 32391033 |
Psychogenic seizure | 86.24 | 11.48 | 37 | 121984 | 329 | 32391176 |
Antipsychotic drug level above therapeutic | 86.08 | 11.48 | 54 | 121967 | 1112 | 32390393 |
Pectus excavatum | 86.02 | 11.48 | 31 | 121990 | 163 | 32391342 |
Prominent epicanthal folds | 85.14 | 11.48 | 30 | 121991 | 146 | 32391359 |
Drug ineffective | 85.08 | 11.48 | 1958 | 120063 | 381519 | 32009986 |
Neutrophil count increased | 84.64 | 11.48 | 187 | 121834 | 15927 | 32375578 |
Hyperkalaemia | 83.56 | 11.48 | 83 | 121938 | 69667 | 32321838 |
Ear disorder | 83.40 | 11.48 | 54 | 121967 | 1177 | 32390328 |
Ligament laxity | 82.43 | 11.48 | 20 | 122001 | 12 | 32391493 |
Fine motor delay | 82.26 | 11.48 | 32 | 121989 | 215 | 32391290 |
Congenital hand malformation | 80.50 | 11.48 | 40 | 121981 | 512 | 32390993 |
Asterixis | 80.11 | 11.48 | 54 | 121967 | 1262 | 32390243 |
Hypermetropia | 79.63 | 11.48 | 36 | 121985 | 367 | 32391138 |
Hypothermia | 79.53 | 11.48 | 139 | 121882 | 9964 | 32381541 |
Hypertonia | 79.20 | 11.48 | 94 | 121927 | 4715 | 32386790 |
Chest discomfort | 79.13 | 11.48 | 45 | 121976 | 50185 | 32341320 |
Oppositional defiant disorder | 79.13 | 11.48 | 39 | 121982 | 490 | 32391015 |
Increased appetite | 78.91 | 11.48 | 109 | 121912 | 6367 | 32385138 |
Hypernatraemia | 77.86 | 11.48 | 123 | 121898 | 8110 | 32383395 |
Disturbance in social behaviour | 77.49 | 11.48 | 58 | 121963 | 1607 | 32389898 |
Chills | 77.38 | 11.48 | 108 | 121913 | 77976 | 32313529 |
Affect lability | 77.01 | 11.48 | 82 | 121939 | 3646 | 32387859 |
Clinodactyly | 76.96 | 11.48 | 31 | 121990 | 231 | 32391274 |
Completed suicide | 76.77 | 11.48 | 602 | 121419 | 91915 | 32299590 |
Pneumonia aspiration | 76.64 | 11.48 | 332 | 121689 | 40824 | 32350681 |
Mucosal inflammation | 76.57 | 11.48 | 16 | 122005 | 33418 | 32358087 |
Headache | 76.50 | 11.48 | 428 | 121593 | 195769 | 32195736 |
Antipsychotic drug level decreased | 76.21 | 11.48 | 46 | 121975 | 882 | 32390623 |
Drug withdrawal convulsions | 75.91 | 11.48 | 50 | 121971 | 1123 | 32390382 |
Scoliosis | 75.21 | 11.48 | 64 | 121957 | 2141 | 32389364 |
Echolalia | 75.12 | 11.48 | 30 | 121991 | 218 | 32391287 |
Anger | 73.99 | 11.48 | 148 | 121873 | 11756 | 32379749 |
Pulmonary embolism | 73.99 | 11.48 | 125 | 121896 | 83534 | 32307971 |
Dyspnoea exertional | 73.67 | 11.48 | 27 | 121994 | 38934 | 32352571 |
Developmental coordination disorder | 73.22 | 11.48 | 26 | 121995 | 130 | 32391375 |
Blood pressure increased | 72.57 | 11.48 | 116 | 121905 | 79238 | 32312267 |
Bipolar I disorder | 72.51 | 11.48 | 44 | 121977 | 852 | 32390653 |
Congenital anomaly | 72.13 | 11.48 | 52 | 121969 | 1358 | 32390147 |
Prostate cancer | 71.96 | 11.48 | 9 | 122012 | 27397 | 32364108 |
Renal impairment | 71.15 | 11.48 | 149 | 121872 | 91823 | 32299682 |
Persecutory delusion | 69.96 | 11.48 | 63 | 121958 | 2276 | 32389229 |
Impulsive behaviour | 69.53 | 11.48 | 61 | 121960 | 2128 | 32389377 |
Prescribed overdose | 68.58 | 11.48 | 126 | 121895 | 9393 | 32382112 |
Eosinophilia | 68.57 | 11.48 | 228 | 121793 | 24730 | 32366775 |
Hypomania | 68.36 | 11.48 | 63 | 121958 | 2346 | 32389159 |
Oculogyric crisis | 68.36 | 11.48 | 51 | 121970 | 1406 | 32390099 |
Dysphoria | 66.67 | 11.48 | 61 | 121960 | 2250 | 32389255 |
Stevens-Johnson syndrome | 66.45 | 11.48 | 187 | 121834 | 18522 | 32372983 |
Obesity | 66.19 | 11.48 | 129 | 121892 | 10053 | 32381452 |
White blood cell count increased | 65.95 | 11.48 | 319 | 121702 | 41083 | 32350422 |
Influenza | 65.90 | 11.48 | 46 | 121975 | 45968 | 32345537 |
Cerebrovascular accident | 65.80 | 11.48 | 141 | 121880 | 86179 | 32305326 |
Microcephaly | 65.67 | 11.48 | 39 | 121982 | 725 | 32390780 |
Nystagmus | 65.30 | 11.48 | 84 | 121937 | 4578 | 32386927 |
Infantile spasms | 65.16 | 11.48 | 29 | 121992 | 284 | 32391221 |
Musculoskeletal pain | 63.96 | 11.48 | 20 | 122001 | 31877 | 32359628 |
Therapeutic product effect variable | 63.76 | 11.48 | 57 | 121964 | 2039 | 32389466 |
Ascites | 63.31 | 11.48 | 36 | 121985 | 40155 | 32351350 |
Weight increased | 63.24 | 11.48 | 533 | 121488 | 83130 | 32308375 |
Urticaria | 62.58 | 11.48 | 79 | 121942 | 59535 | 32331970 |
Dehydration | 62.01 | 11.48 | 261 | 121760 | 128697 | 32262808 |
Epistaxis | 61.83 | 11.48 | 71 | 121950 | 55784 | 32335721 |
Muscle spasms | 61.54 | 11.48 | 106 | 121915 | 70312 | 32321193 |
Ear malformation | 60.88 | 11.48 | 28 | 121993 | 298 | 32391207 |
Decreased eye contact | 60.70 | 11.48 | 32 | 121989 | 467 | 32391038 |
Fluid retention | 60.20 | 11.48 | 13 | 122008 | 26537 | 32364968 |
Craniosynostosis | 60.15 | 11.48 | 28 | 121993 | 307 | 32391198 |
Nasal disorder | 59.12 | 11.48 | 48 | 121973 | 1502 | 32390003 |
Brain oedema | 58.82 | 11.48 | 142 | 121879 | 12818 | 32378687 |
Weight decreased | 58.67 | 11.48 | 370 | 121651 | 164448 | 32227057 |
Fine motor skill dysfunction | 58.35 | 11.48 | 49 | 121972 | 1609 | 32389896 |
Pressure of speech | 58.12 | 11.48 | 31 | 121990 | 464 | 32391041 |
Dyslexia | 57.93 | 11.48 | 27 | 121994 | 297 | 32391208 |
Stereotypy | 57.80 | 11.48 | 35 | 121986 | 675 | 32390830 |
Exposure during pregnancy | 57.67 | 11.48 | 115 | 121906 | 9114 | 32382391 |
Melaena | 57.61 | 11.48 | 29 | 121992 | 34636 | 32356869 |
Angina pectoris | 57.38 | 11.48 | 23 | 121998 | 31403 | 32360102 |
Serotonin syndrome | 57.36 | 11.48 | 180 | 121841 | 18937 | 32372568 |
Abdominal pain upper | 57.36 | 11.48 | 103 | 121918 | 67235 | 32324270 |
Atonic seizures | 57.26 | 11.48 | 23 | 121998 | 170 | 32391335 |
Hypersensitivity | 57.10 | 11.48 | 80 | 121941 | 57678 | 32333827 |
Sleep disorder | 57.03 | 11.48 | 225 | 121796 | 26527 | 32364978 |
Stupor | 56.60 | 11.48 | 63 | 121958 | 2946 | 32388559 |
Confusional state | 56.53 | 11.48 | 801 | 121220 | 142314 | 32249191 |
Blood creatinine increased | 56.46 | 11.48 | 179 | 121842 | 95953 | 32295552 |
Differential white blood cell count abnormal | 56.12 | 11.48 | 44 | 121977 | 1308 | 32390197 |
Drug abuse | 55.84 | 11.48 | 502 | 121519 | 79741 | 32311764 |
Asocial behaviour | 55.14 | 11.48 | 17 | 122004 | 49 | 32391456 |
Psychotic symptom | 55.00 | 11.48 | 45 | 121976 | 1424 | 32390081 |
Erythema | 54.42 | 11.48 | 147 | 121874 | 82958 | 32308547 |
Physical assault | 54.27 | 11.48 | 40 | 121981 | 1082 | 32390423 |
Pancytopenia | 54.20 | 11.48 | 169 | 121852 | 91066 | 32300439 |
Osteonecrosis of jaw | 53.62 | 11.48 | 5 | 122016 | 19161 | 32372344 |
Upper gastrointestinal haemorrhage | 53.42 | 11.48 | 12 | 122009 | 23837 | 32367668 |
Personality disorder | 53.32 | 11.48 | 41 | 121980 | 1184 | 32390321 |
Personal relationship issue | 53.14 | 11.48 | 24 | 121997 | 244 | 32391261 |
Hypoaesthesia | 52.68 | 11.48 | 86 | 121935 | 58267 | 32333238 |
Plagiocephaly | 52.46 | 11.48 | 27 | 121994 | 374 | 32391131 |
Herpes zoster | 52.34 | 11.48 | 28 | 121993 | 32313 | 32359192 |
Septic shock | 52.31 | 11.48 | 113 | 121908 | 68876 | 32322629 |
Psychiatric symptom | 52.30 | 11.48 | 66 | 121955 | 3528 | 32387977 |
Congenital eye disorder | 52.10 | 11.48 | 19 | 122002 | 104 | 32391401 |
Hypermobility syndrome | 52.04 | 11.48 | 26 | 121995 | 337 | 32391168 |
General physical health deterioration | 51.93 | 11.48 | 239 | 121782 | 115020 | 32276485 |
Congenital eyelid malformation | 51.42 | 11.48 | 16 | 122005 | 48 | 32391457 |
Chronic kidney disease | 50.88 | 11.48 | 45 | 121976 | 39930 | 32351575 |
Atrial septal defect | 50.62 | 11.48 | 93 | 121928 | 6932 | 32384573 |
Urinary incontinence | 50.61 | 11.48 | 167 | 121854 | 18040 | 32373465 |
Sinusitis | 50.46 | 11.48 | 38 | 121983 | 36522 | 32354983 |
Sedation complication | 50.22 | 11.48 | 39 | 121982 | 1143 | 32390362 |
Bruxism | 50.05 | 11.48 | 45 | 121976 | 1622 | 32389883 |
Syncope | 50.03 | 11.48 | 172 | 121849 | 89952 | 32301553 |
Mental status changes | 49.72 | 11.48 | 279 | 121742 | 38058 | 32353447 |
Arthritis | 49.61 | 11.48 | 19 | 122002 | 26673 | 32364832 |
Drug level changed | 49.57 | 11.48 | 25 | 121996 | 331 | 32391174 |
Bradykinesia | 49.04 | 11.48 | 70 | 121951 | 4216 | 32387289 |
Anaphylactic reaction | 49.01 | 11.48 | 26 | 121995 | 30146 | 32361359 |
Camptodactyly congenital | 48.97 | 11.48 | 15 | 122006 | 42 | 32391463 |
Gait disturbance | 48.96 | 11.48 | 489 | 121532 | 79919 | 32311586 |
Motor dysfunction | 48.08 | 11.48 | 87 | 121934 | 6409 | 32385096 |
Blood prolactin increased | 47.55 | 11.48 | 43 | 121978 | 1562 | 32389943 |
Leukopenia | 47.53 | 11.48 | 387 | 121634 | 59735 | 32331770 |
Eosinophilic pleural effusion | 47.44 | 11.48 | 22 | 121999 | 239 | 32391266 |
Normal pressure hydrocephalus | 47.24 | 11.48 | 19 | 122002 | 141 | 32391364 |
Homicidal ideation | 46.82 | 11.48 | 54 | 121967 | 2626 | 32388879 |
Toxic encephalopathy | 46.57 | 11.48 | 74 | 121947 | 4903 | 32386602 |
Nose deformity | 46.56 | 11.48 | 19 | 122002 | 147 | 32391358 |
Haematochezia | 46.55 | 11.48 | 47 | 121974 | 39161 | 32352344 |
Respiratory failure | 46.08 | 11.48 | 226 | 121795 | 106956 | 32284549 |
Haemoptysis | 46.07 | 11.48 | 35 | 121986 | 33490 | 32358015 |
Diabetes insipidus | 45.93 | 11.48 | 53 | 121968 | 2579 | 32388926 |
Congenital hair disorder | 45.89 | 11.48 | 10 | 122011 | 0 | 32391505 |
Gaze palsy | 45.42 | 11.48 | 39 | 121982 | 1321 | 32390184 |
Hyperacusis | 45.41 | 11.48 | 31 | 121990 | 740 | 32390765 |
Multiple congenital abnormalities | 45.13 | 11.48 | 27 | 121994 | 509 | 32390996 |
Lethargy | 45.11 | 11.48 | 287 | 121734 | 40941 | 32350564 |
Hyperosmolar state | 44.96 | 11.48 | 25 | 121996 | 408 | 32391097 |
Hyperprolactinaemia | 44.43 | 11.48 | 38 | 121983 | 1280 | 32390225 |
Cytomegalovirus infection | 44.31 | 11.48 | 20 | 122001 | 25444 | 32366061 |
Rectal haemorrhage | 44.27 | 11.48 | 45 | 121976 | 37378 | 32354127 |
Psoriatic arthropathy | 44.23 | 11.48 | 7 | 122014 | 17853 | 32373652 |
Arthropathy | 43.51 | 11.48 | 15 | 122006 | 22474 | 32369031 |
Pneumonitis | 43.31 | 11.48 | 30 | 121991 | 30104 | 32361401 |
Pneumocystis jirovecii pneumonia | 43.27 | 11.48 | 9 | 122012 | 18861 | 32372644 |
Basal cell carcinoma | 43.25 | 11.48 | 7 | 122014 | 17561 | 32373944 |
Swelling | 42.93 | 11.48 | 48 | 121973 | 38174 | 32353331 |
Spina bifida | 42.61 | 11.48 | 23 | 121998 | 353 | 32391152 |
Arnold-Chiari malformation | 42.48 | 11.48 | 22 | 121999 | 309 | 32391196 |
Cerebellar atrophy | 42.47 | 11.48 | 25 | 121996 | 457 | 32391048 |
Social avoidant behaviour | 42.25 | 11.48 | 56 | 121965 | 3143 | 32388362 |
Knee deformity | 42.15 | 11.48 | 26 | 121995 | 519 | 32390986 |
Paraesthesia | 41.88 | 11.48 | 100 | 121921 | 58844 | 32332661 |
Palmar-plantar erythrodysaesthesia syndrome | 41.77 | 11.48 | 5 | 122016 | 15744 | 32375761 |
Hyperkinesia | 41.59 | 11.48 | 47 | 121974 | 2235 | 32389270 |
High arched palate | 41.54 | 11.48 | 14 | 122007 | 58 | 32391447 |
Acidosis hyperchloraemic | 41.51 | 11.48 | 21 | 122000 | 280 | 32391225 |
Homicide | 41.11 | 11.48 | 32 | 121989 | 941 | 32390564 |
Choreoathetosis | 41.05 | 11.48 | 33 | 121988 | 1018 | 32390487 |
Malaise | 40.96 | 11.48 | 446 | 121575 | 176692 | 32214813 |
Rash | 40.83 | 11.48 | 547 | 121474 | 208786 | 32182719 |
Seizure cluster | 40.70 | 11.48 | 16 | 122005 | 111 | 32391394 |
Cerebral atrophy | 40.57 | 11.48 | 66 | 121955 | 4461 | 32387044 |
Monocyte count increased | 40.20 | 11.48 | 61 | 121960 | 3883 | 32387622 |
Abdominal discomfort | 40.05 | 11.48 | 86 | 121935 | 52538 | 32338967 |
Cerebral ventricle dilatation | 39.82 | 11.48 | 31 | 121990 | 912 | 32390593 |
Cogwheel rigidity | 39.66 | 11.48 | 36 | 121985 | 1314 | 32390191 |
Chorea | 39.60 | 11.48 | 33 | 121988 | 1072 | 32390433 |
Lung disorder | 39.46 | 11.48 | 41 | 121980 | 33713 | 32357792 |
Loss of personal independence in daily activities | 39.36 | 11.48 | 202 | 121819 | 26631 | 32364874 |
Reading disorder | 39.33 | 11.48 | 23 | 121998 | 415 | 32391090 |
Anisometropia | 39.33 | 11.48 | 13 | 122008 | 50 | 32391455 |
Cytokine release syndrome | 39.32 | 11.48 | 3 | 122018 | 13532 | 32377973 |
Full blood count decreased | 39.24 | 11.48 | 8 | 122013 | 17002 | 32374503 |
Encopresis | 38.41 | 11.48 | 15 | 122006 | 102 | 32391403 |
Pancreatitis | 38.35 | 11.48 | 260 | 121761 | 37891 | 32353614 |
Nipple disorder | 38.07 | 11.48 | 18 | 122003 | 205 | 32391300 |
Ear infection | 37.73 | 11.48 | 92 | 121929 | 8356 | 32383149 |
Delusional disorder, unspecified type | 37.56 | 11.48 | 28 | 121993 | 771 | 32390734 |
Dyscalculia | 37.53 | 11.48 | 11 | 122010 | 25 | 32391480 |
Stomatitis | 37.53 | 11.48 | 58 | 121963 | 40171 | 32351334 |
Haemorrhage | 37.47 | 11.48 | 81 | 121940 | 49367 | 32342138 |
Eosinophil count decreased | 37.28 | 11.48 | 34 | 121987 | 1249 | 32390256 |
Congenital musculoskeletal anomaly | 37.25 | 11.48 | 19 | 122002 | 258 | 32391247 |
Autonomic nervous system imbalance | 37.23 | 11.48 | 47 | 121974 | 2513 | 32388992 |
Postictal paralysis | 37.21 | 11.48 | 17 | 122004 | 178 | 32391327 |
Logorrhoea | 37.08 | 11.48 | 46 | 121975 | 2416 | 32389089 |
Faecaloma | 36.87 | 11.48 | 65 | 121956 | 4691 | 32386814 |
Necrosis ischaemic | 36.81 | 11.48 | 18 | 122003 | 222 | 32391283 |
Congenital myopia | 36.78 | 11.48 | 10 | 122011 | 15 | 32391490 |
Acute myeloid leukaemia | 36.73 | 11.48 | 13 | 122008 | 19161 | 32372344 |
Carnitine decreased | 36.71 | 11.48 | 8 | 122013 | 0 | 32391505 |
Affective disorder | 36.51 | 11.48 | 55 | 121966 | 3478 | 32388027 |
Excessive eye blinking | 36.48 | 11.48 | 22 | 121999 | 421 | 32391084 |
Apathy | 36.48 | 11.48 | 79 | 121942 | 6636 | 32384869 |
Dysmetria | 36.15 | 11.48 | 21 | 122000 | 374 | 32391131 |
Pleurothotonus | 36.10 | 11.48 | 31 | 121990 | 1050 | 32390455 |
Dysgeusia | 35.92 | 11.48 | 26 | 121995 | 25505 | 32366000 |
Hypotension | 35.79 | 11.48 | 583 | 121438 | 215527 | 32175978 |
Congenital nail disorder | 35.60 | 11.48 | 11 | 122010 | 32 | 32391473 |
Coma scale abnormal | 35.42 | 11.48 | 55 | 121966 | 3572 | 32387933 |
Brugada syndrome | 35.41 | 11.48 | 26 | 121995 | 699 | 32390806 |
Angioedema | 35.13 | 11.48 | 51 | 121970 | 36238 | 32355267 |
Tooth malformation | 35.10 | 11.48 | 15 | 122006 | 132 | 32391373 |
COVID-19 | 35.09 | 11.48 | 41 | 121980 | 31974 | 32359531 |
Renal disorder | 34.97 | 11.48 | 26 | 121995 | 25157 | 32366348 |
Neoplasm progression | 34.90 | 11.48 | 15 | 122006 | 19643 | 32371862 |
Flight of ideas | 34.64 | 11.48 | 20 | 122001 | 352 | 32391153 |
Haematuria | 34.39 | 11.48 | 82 | 121939 | 48279 | 32343226 |
Lymphocyte count increased | 34.27 | 11.48 | 47 | 121974 | 2726 | 32388779 |
International normalised ratio increased | 34.19 | 11.48 | 84 | 121937 | 48951 | 32342554 |
Pancreatitis acute | 34.17 | 11.48 | 197 | 121824 | 27138 | 32364367 |
Transient ischaemic attack | 34.09 | 11.48 | 28 | 121993 | 25766 | 32365739 |
Gastrointestinal malformation | 33.97 | 11.48 | 11 | 122010 | 39 | 32391466 |
Coloboma | 33.96 | 11.48 | 15 | 122006 | 144 | 32391361 |
Crying | 33.91 | 11.48 | 71 | 121950 | 5825 | 32385680 |
Bacteraemia | 33.70 | 11.48 | 12 | 122009 | 17621 | 32373884 |
Mood altered | 33.60 | 11.48 | 91 | 121930 | 8813 | 32382692 |
Colitis | 33.57 | 11.48 | 47 | 121974 | 33904 | 32357601 |
Delusion of grandeur | 33.54 | 11.48 | 21 | 122000 | 431 | 32391074 |
Osteoarthritis | 33.51 | 11.48 | 16 | 122005 | 19703 | 32371802 |
Oedema | 33.35 | 11.48 | 75 | 121946 | 45072 | 32346433 |
Distractibility | 33.28 | 11.48 | 19 | 122002 | 327 | 32391178 |
Tumour lysis syndrome | 33.23 | 11.48 | 7 | 122014 | 14540 | 32376965 |
Drop attacks | 33.05 | 11.48 | 23 | 121998 | 567 | 32390938 |
Emotional disorder | 33.04 | 11.48 | 67 | 121954 | 5374 | 32386131 |
Staphylococcal infection | 32.99 | 11.48 | 44 | 121977 | 32395 | 32359110 |
Anaphylactic shock | 32.80 | 11.48 | 8 | 122013 | 15026 | 32376479 |
Bronchopulmonary aspergillosis | 32.49 | 11.48 | 6 | 122015 | 13681 | 32377824 |
Soliloquy | 32.48 | 11.48 | 20 | 122001 | 398 | 32391107 |
Nasal septum disorder | 32.37 | 11.48 | 11 | 122010 | 47 | 32391458 |
Bone pain | 32.35 | 11.48 | 18 | 122003 | 20326 | 32371179 |
Arachnodactyly | 32.26 | 11.48 | 8 | 122013 | 6 | 32391499 |
Intelligence test abnormal | 32.17 | 11.48 | 9 | 122012 | 16 | 32391489 |
Confabulation | 32.10 | 11.48 | 14 | 122007 | 130 | 32391375 |
Postictal psychosis | 32.10 | 11.48 | 14 | 122007 | 130 | 32391375 |
Anion gap increased | 31.97 | 11.48 | 36 | 121985 | 1705 | 32389800 |
Pneumothorax | 31.84 | 11.48 | 13 | 122008 | 17557 | 32373948 |
Retinal coloboma | 31.82 | 11.48 | 9 | 122012 | 17 | 32391488 |
Deep vein thrombosis | 31.80 | 11.48 | 127 | 121894 | 63586 | 32327919 |
Injection site pain | 31.47 | 11.48 | 47 | 121974 | 33011 | 32358494 |
Atrial flutter | 31.38 | 11.48 | 9 | 122012 | 15174 | 32376331 |
Chronic obstructive pulmonary disease | 31.33 | 11.48 | 87 | 121934 | 48666 | 32342839 |
Congenital astigmatism | 31.16 | 11.48 | 9 | 122012 | 19 | 32391486 |
Haemoglobin decreased | 31.07 | 11.48 | 293 | 121728 | 119378 | 32272127 |
Inappropriate affect | 31.00 | 11.48 | 22 | 121999 | 560 | 32390945 |
Flushing | 30.87 | 11.48 | 43 | 121978 | 31084 | 32360421 |
Postictal state | 30.77 | 11.48 | 25 | 121996 | 783 | 32390722 |
Tonic convulsion | 30.74 | 11.48 | 27 | 121994 | 943 | 32390562 |
Product dose omission issue | 30.71 | 11.48 | 242 | 121779 | 102333 | 32289172 |
Decreased appetite | 30.68 | 11.48 | 422 | 121599 | 160391 | 32231114 |
Perseveration | 30.65 | 11.48 | 13 | 122008 | 112 | 32391393 |
Sexually inappropriate behaviour | 30.56 | 11.48 | 20 | 122001 | 444 | 32391061 |
Congenital knee deformity | 30.55 | 11.48 | 13 | 122008 | 113 | 32391392 |
Prognathism | 30.34 | 11.48 | 11 | 122010 | 59 | 32391446 |
Inappropriate antidiuretic hormone secretion | 30.32 | 11.48 | 107 | 121914 | 11956 | 32379549 |
Fluid overload | 30.29 | 11.48 | 18 | 122003 | 19603 | 32371902 |
Angina unstable | 30.24 | 11.48 | 5 | 122016 | 12350 | 32379155 |
Laboratory test abnormal | 30.19 | 11.48 | 17 | 122004 | 19070 | 32372435 |
Pharyngeal disorder | 30.14 | 11.48 | 22 | 121999 | 586 | 32390919 |
Convulsive threshold lowered | 30.13 | 11.48 | 21 | 122000 | 519 | 32390986 |
Synovitis | 30.00 | 11.48 | 3 | 122018 | 10875 | 32380630 |
Hypokalaemia | 29.98 | 11.48 | 106 | 121915 | 54988 | 32336517 |
Dacryostenosis congenital | 29.97 | 11.48 | 9 | 122012 | 23 | 32391482 |
Illiteracy | 29.83 | 11.48 | 8 | 122013 | 11 | 32391494 |
Heart disease congenital | 29.75 | 11.48 | 31 | 121990 | 1344 | 32390161 |
Apraxia | 29.74 | 11.48 | 30 | 121991 | 1251 | 32390254 |
Memory impairment | 29.56 | 11.48 | 256 | 121765 | 40223 | 32351282 |
Antisocial behaviour | 29.35 | 11.48 | 17 | 122004 | 301 | 32391204 |
Acute coronary syndrome | 29.30 | 11.48 | 8 | 122013 | 13933 | 32377572 |
Medication error | 29.21 | 11.48 | 164 | 121857 | 22371 | 32369134 |
Developmental hip dysplasia | 29.21 | 11.48 | 17 | 122004 | 304 | 32391201 |
Anxiety | 29.01 | 11.48 | 514 | 121507 | 95491 | 32296014 |
Hepatic adenoma | 29.01 | 11.48 | 10 | 122011 | 45 | 32391460 |
Night sweats | 29.00 | 11.48 | 12 | 122009 | 16076 | 32375429 |
Anticonvulsant drug level abnormal | 28.93 | 11.48 | 9 | 122012 | 27 | 32391478 |
Metabolic syndrome | 28.76 | 11.48 | 33 | 121988 | 1596 | 32389909 |
Myelodysplastic syndrome | 28.73 | 11.48 | 20 | 122001 | 20018 | 32371487 |
Torticollis | 28.45 | 11.48 | 28 | 121993 | 1133 | 32390372 |
Emotional disorder of childhood | 28.45 | 11.48 | 9 | 122012 | 29 | 32391476 |
Posture abnormal | 28.37 | 11.48 | 38 | 121983 | 2155 | 32389350 |
Pelvic deformity | 28.32 | 11.48 | 8 | 122013 | 15 | 32391490 |
Nasopharyngitis | 28.27 | 11.48 | 133 | 121888 | 63654 | 32327851 |
Bronchiolitis | 28.21 | 11.48 | 44 | 121977 | 2869 | 32388636 |
Eosinophil count increased | 28.20 | 11.48 | 82 | 121939 | 8273 | 32383232 |
Bladder cancer | 27.84 | 11.48 | 3 | 122018 | 10253 | 32381252 |
Hypotelorism of orbit | 27.75 | 11.48 | 12 | 122009 | 109 | 32391396 |
Dyslipidaemia | 27.65 | 11.48 | 72 | 121949 | 6811 | 32384694 |
Meningocele | 27.56 | 11.48 | 9 | 122012 | 33 | 32391472 |
Factor XIII deficiency | 27.53 | 11.48 | 6 | 122015 | 0 | 32391505 |
Toe walking | 27.53 | 11.48 | 6 | 122015 | 0 | 32391505 |
Mutism | 27.34 | 11.48 | 23 | 121998 | 757 | 32390748 |
Executive dysfunction | 27.20 | 11.48 | 14 | 122007 | 194 | 32391311 |
Muscle tone disorder | 27.20 | 11.48 | 13 | 122008 | 152 | 32391353 |
Intensive care unit acquired weakness | 27.19 | 11.48 | 25 | 121996 | 928 | 32390577 |
Renal injury | 27.13 | 11.48 | 6 | 122015 | 12049 | 32379456 |
Cellulitis | 27.09 | 11.48 | 97 | 121924 | 50133 | 32341372 |
Cleft palate | 27.08 | 11.48 | 21 | 122000 | 614 | 32390891 |
Selective eating disorder | 27.06 | 11.48 | 33 | 121988 | 1703 | 32389802 |
Scaphocephaly | 27.05 | 11.48 | 8 | 122013 | 19 | 32391486 |
Pulmonary fibrosis | 27.02 | 11.48 | 15 | 122006 | 16959 | 32374546 |
Drug level above therapeutic | 26.98 | 11.48 | 46 | 121975 | 3232 | 32388273 |
Device related infection | 26.92 | 11.48 | 17 | 122004 | 17916 | 32373589 |
Nephrolithiasis | 26.91 | 11.48 | 38 | 121983 | 27316 | 32364189 |
Rhinorrhoea | 26.77 | 11.48 | 28 | 121993 | 22958 | 32368547 |
Phobia | 26.75 | 11.48 | 13 | 122008 | 158 | 32391347 |
Blood potassium decreased | 26.63 | 11.48 | 16 | 122005 | 17322 | 32374183 |
Drug hypersensitivity | 26.47 | 11.48 | 164 | 121857 | 73236 | 32318269 |
Unresponsive to stimuli | 26.47 | 11.48 | 186 | 121835 | 27423 | 32364082 |
Abdominal distension | 26.40 | 11.48 | 101 | 121920 | 51194 | 32340311 |
Sluggishness | 26.32 | 11.48 | 46 | 121975 | 3297 | 32388208 |
Infection | 26.22 | 11.48 | 198 | 121823 | 84517 | 32306988 |
Gross motor delay | 26.18 | 11.48 | 15 | 122006 | 260 | 32391245 |
Duodenal ulcer | 26.11 | 11.48 | 4 | 122017 | 10451 | 32381054 |
Osteomyelitis | 26.09 | 11.48 | 13 | 122008 | 15620 | 32375885 |
Head titubation | 26.08 | 11.48 | 15 | 122006 | 262 | 32391243 |
Angular cheilitis | 26.05 | 11.48 | 13 | 122008 | 168 | 32391337 |
Bicuspid aortic valve | 26.04 | 11.48 | 14 | 122007 | 213 | 32391292 |
Heart rate decreased | 25.81 | 11.48 | 34 | 121987 | 25166 | 32366339 |
Circadian rhythm sleep disorder | 25.79 | 11.48 | 18 | 122003 | 446 | 32391059 |
Paradoxical drug reaction | 25.65 | 11.48 | 42 | 121979 | 2854 | 32388651 |
Food interaction | 25.57 | 11.48 | 24 | 121997 | 915 | 32390590 |
Cerebral palsy | 25.43 | 11.48 | 11 | 122010 | 100 | 32391405 |
Diabetic hyperosmolar coma | 25.42 | 11.48 | 17 | 122004 | 392 | 32391113 |
Staring | 25.41 | 11.48 | 30 | 121991 | 1496 | 32390009 |
Condition aggravated | 25.34 | 11.48 | 764 | 121257 | 154897 | 32236608 |
Pyrexia | 25.29 | 11.48 | 964 | 121057 | 319004 | 32072501 |
Blood pressure fluctuation | 25.22 | 11.48 | 23 | 121998 | 20112 | 32371393 |
Choroidal coloboma | 25.11 | 11.48 | 6 | 122015 | 3 | 32391502 |
Retrognathia | 25.10 | 11.48 | 14 | 122007 | 230 | 32391275 |
Blood bilirubin increased | 25.07 | 11.48 | 69 | 121952 | 38715 | 32352790 |
Urinary tract infection | 24.85 | 11.48 | 187 | 121834 | 79884 | 32311621 |
Peritonitis bacterial | 24.76 | 11.48 | 8 | 122013 | 12488 | 32379017 |
Hypertension | 24.66 | 11.48 | 347 | 121674 | 131403 | 32260102 |
Balance disorder | 24.49 | 11.48 | 241 | 121780 | 39218 | 32352287 |
Microstomia | 24.48 | 11.48 | 6 | 122015 | 4 | 32391501 |
Water intoxication | 24.48 | 11.48 | 18 | 122003 | 485 | 32391020 |
Intentional product use issue | 24.48 | 11.48 | 79 | 121942 | 42132 | 32349373 |
Acute hepatic failure | 24.42 | 11.48 | 105 | 121916 | 12864 | 32378641 |
Metastases to liver | 24.37 | 11.48 | 9 | 122012 | 12923 | 32378582 |
Aptyalism | 24.34 | 11.48 | 15 | 122006 | 299 | 32391206 |
Renal tubular necrosis | 24.19 | 11.48 | 15 | 122006 | 15963 | 32375542 |
Basilar artery occlusion | 24.11 | 11.48 | 10 | 122011 | 81 | 32391424 |
Psychiatric decompensation | 24.08 | 11.48 | 29 | 121992 | 1477 | 32390028 |
Peritonitis | 24.04 | 11.48 | 29 | 121992 | 22301 | 32369204 |
Post-injection delirium sedation syndrome | 24.01 | 11.48 | 17 | 122004 | 431 | 32391074 |
Neural tube defect | 23.99 | 11.48 | 9 | 122012 | 54 | 32391451 |
Judgement impaired | 23.99 | 11.48 | 20 | 122001 | 650 | 32390855 |
Gout | 23.93 | 11.48 | 21 | 122000 | 18707 | 32372798 |
Faeces discoloured | 23.89 | 11.48 | 13 | 122008 | 14864 | 32376641 |
Choking | 23.86 | 11.48 | 57 | 121964 | 5109 | 32386396 |
Brain malformation | 23.84 | 11.48 | 11 | 122010 | 118 | 32391387 |
Grandiosity | 23.53 | 11.48 | 15 | 122006 | 318 | 32391187 |
Spine malformation | 23.50 | 11.48 | 13 | 122008 | 210 | 32391295 |
Rash pruritic | 23.41 | 11.48 | 35 | 121986 | 24576 | 32366929 |
Oropharyngeal discomfort | 23.31 | 11.48 | 35 | 121986 | 2207 | 32389298 |
Drug intolerance | 23.29 | 11.48 | 103 | 121918 | 50132 | 32341373 |
Oligoasthenozoospermia | 23.28 | 11.48 | 7 | 122014 | 18 | 32391487 |
Hot flush | 23.26 | 11.48 | 15 | 122006 | 15631 | 32375874 |
Congenital scoliosis | 23.21 | 11.48 | 8 | 122013 | 36 | 32391469 |
Aminoaciduria | 23.21 | 11.48 | 11 | 122010 | 126 | 32391379 |
Tonic clonic movements | 23.20 | 11.48 | 25 | 121996 | 1127 | 32390378 |
Neoplasm malignant | 23.15 | 11.48 | 22 | 121999 | 18863 | 32372642 |
Cerebral haemorrhage | 23.08 | 11.48 | 61 | 121960 | 34686 | 32356819 |
Metabolic acidosis | 23.07 | 11.48 | 244 | 121777 | 40455 | 32351050 |
Nephropathy toxic | 23.05 | 11.48 | 8 | 122013 | 11938 | 32379567 |
Social (pragmatic) communication disorder | 22.95 | 11.48 | 9 | 122012 | 62 | 32391443 |
Congenital neurological disorder | 22.95 | 11.48 | 5 | 122016 | 0 | 32391505 |
Negativism | 22.90 | 11.48 | 16 | 122005 | 397 | 32391108 |
Visuospatial deficit | 22.82 | 11.48 | 9 | 122012 | 63 | 32391442 |
Metastases to bone | 22.79 | 11.48 | 6 | 122015 | 10704 | 32380801 |
Pulmonary hypertension | 22.72 | 11.48 | 26 | 121995 | 20468 | 32371037 |
Neuralgia | 22.71 | 11.48 | 8 | 122013 | 11827 | 32379678 |
Frustration tolerance decreased | 22.70 | 11.48 | 35 | 121986 | 2259 | 32389246 |
Deformity thorax | 22.69 | 11.48 | 8 | 122013 | 39 | 32391466 |
Speech sound disorder | 22.62 | 11.48 | 11 | 122010 | 134 | 32391371 |
Strabismus congenital | 22.53 | 11.48 | 8 | 122013 | 40 | 32391465 |
Limb hypoplasia congenital | 22.50 | 11.48 | 7 | 122014 | 21 | 32391484 |
Growth retardation | 22.29 | 11.48 | 30 | 121991 | 1709 | 32389796 |
Decreased gait velocity | 22.26 | 11.48 | 11 | 122010 | 139 | 32391366 |
Middle insomnia | 22.23 | 11.48 | 64 | 121957 | 6420 | 32385085 |
Depressive symptom | 22.23 | 11.48 | 31 | 121990 | 1827 | 32389678 |
Tic | 22.21 | 11.48 | 33 | 121988 | 2061 | 32389444 |
Self-injurious ideation | 22.19 | 11.48 | 29 | 121992 | 1605 | 32389900 |
Inflammation | 22.19 | 11.48 | 36 | 121985 | 24457 | 32367048 |
Inguinal hernia | 22.15 | 11.48 | 73 | 121948 | 7879 | 32383626 |
Type 2 diabetes mellitus | 22.09 | 11.48 | 114 | 121907 | 15058 | 32376447 |
Salivary gland enlargement | 22.02 | 11.48 | 7 | 122014 | 23 | 32391482 |
Amblyopia | 22.01 | 11.48 | 9 | 122012 | 70 | 32391435 |
Localised infection | 21.98 | 11.48 | 15 | 122006 | 15172 | 32376333 |
Mood swings | 21.89 | 11.48 | 74 | 121947 | 8091 | 32383414 |
Pulmonary arterial hypertension | 21.87 | 11.48 | 5 | 122016 | 9816 | 32381689 |
Hyperthermia | 21.87 | 11.48 | 89 | 121932 | 10639 | 32380866 |
Energy increased | 21.82 | 11.48 | 26 | 121995 | 1309 | 32390196 |
Patent ductus arteriosus | 21.81 | 11.48 | 42 | 121979 | 3243 | 32388262 |
Throat irritation | 21.73 | 11.48 | 5 | 122016 | 9773 | 32381732 |
Conductive deafness | 21.72 | 11.48 | 11 | 122010 | 147 | 32391358 |
Diffuse large B-cell lymphoma | 21.68 | 11.48 | 3 | 122018 | 8459 | 32383046 |
Overweight | 21.68 | 11.48 | 29 | 121992 | 1642 | 32389863 |
Patient isolation | 21.58 | 11.48 | 7 | 122014 | 25 | 32391480 |
Foetal growth restriction | 21.56 | 11.48 | 47 | 121974 | 3965 | 32387540 |
Febrile bone marrow aplasia | 21.52 | 11.48 | 3 | 122018 | 8412 | 32383093 |
Movement disorder | 21.48 | 11.48 | 90 | 121931 | 10901 | 32380604 |
Muscular weakness | 21.38 | 11.48 | 158 | 121863 | 67771 | 32323734 |
Epidermolysis bullosa | 21.38 | 11.48 | 10 | 122011 | 111 | 32391394 |
Tachycardia | 21.31 | 11.48 | 416 | 121605 | 78672 | 32312833 |
Candida infection | 21.28 | 11.48 | 19 | 122002 | 16784 | 32374721 |
Pulmonary mass | 21.13 | 11.48 | 9 | 122012 | 11851 | 32379654 |
Hallucination, visual | 21.01 | 11.48 | 123 | 121898 | 17036 | 32374469 |
Flatulence | 20.98 | 11.48 | 25 | 121996 | 19330 | 32372175 |
Clostridium difficile colitis | 20.95 | 11.48 | 14 | 122007 | 14317 | 32377188 |
Ventricular tachycardia | 20.94 | 11.48 | 40 | 121981 | 25516 | 32365989 |
Subacute endocarditis | 20.92 | 11.48 | 8 | 122013 | 51 | 32391454 |
Miosis | 20.85 | 11.48 | 76 | 121945 | 8628 | 32382877 |
Shock haemorrhagic | 20.76 | 11.48 | 7 | 122014 | 10638 | 32380867 |
Incontinence | 20.73 | 11.48 | 57 | 121964 | 5569 | 32385936 |
Cholestasis | 20.71 | 11.48 | 44 | 121977 | 26989 | 32364516 |
Blood triglycerides increased | 20.70 | 11.48 | 109 | 121912 | 14510 | 32376995 |
Head deformity | 20.69 | 11.48 | 9 | 122012 | 83 | 32391422 |
Ammonia abnormal | 20.69 | 11.48 | 9 | 122012 | 83 | 32391422 |
Blood osmolarity decreased | 20.68 | 11.48 | 18 | 122003 | 621 | 32390884 |
Lacrimal gland enlargement | 20.61 | 11.48 | 5 | 122016 | 3 | 32391502 |
Gastric volvulus | 20.61 | 11.48 | 5 | 122016 | 3 | 32391502 |
Sensory integrative dysfunction | 20.58 | 11.48 | 7 | 122014 | 30 | 32391475 |
Dry skin | 20.55 | 11.48 | 39 | 121982 | 24939 | 32366566 |
Mydriasis | 20.55 | 11.48 | 62 | 121959 | 6384 | 32385121 |
Delusional perception | 20.54 | 11.48 | 11 | 122010 | 166 | 32391339 |
Mucosal ulceration | 20.54 | 11.48 | 21 | 122000 | 890 | 32390615 |
Transplant rejection | 20.53 | 11.48 | 6 | 122015 | 9993 | 32381512 |
Dissociation | 20.50 | 11.48 | 24 | 121997 | 1186 | 32390319 |
Madarosis | 20.50 | 11.48 | 12 | 122009 | 217 | 32391288 |
Bone marrow failure | 20.48 | 11.48 | 53 | 121968 | 30351 | 32361154 |
Impaired healing | 20.40 | 11.48 | 16 | 122005 | 15068 | 32376437 |
Depressed mood | 20.39 | 11.48 | 128 | 121893 | 18172 | 32373333 |
Clostridium difficile infection | 20.37 | 11.48 | 22 | 121999 | 17774 | 32373731 |
Type 1 diabetes mellitus | 20.35 | 11.48 | 46 | 121975 | 3977 | 32387528 |
Tachyphrenia | 20.34 | 11.48 | 24 | 121997 | 1196 | 32390309 |
Impaired reasoning | 20.33 | 11.48 | 10 | 122011 | 125 | 32391380 |
Myoglobinuria | 20.33 | 11.48 | 20 | 122001 | 809 | 32390696 |
COVID-19 pneumonia | 20.32 | 11.48 | 4 | 122017 | 8716 | 32382789 |
Constipation | 20.19 | 11.48 | 343 | 121678 | 126030 | 32265475 |
Ventricular septal defect | 20.18 | 11.48 | 44 | 121977 | 3713 | 32387792 |
Carnitine deficiency | 20.17 | 11.48 | 8 | 122013 | 57 | 32391448 |
Sarcopenia | 20.16 | 11.48 | 14 | 122007 | 344 | 32391161 |
Hyponatraemia | 20.09 | 11.48 | 392 | 121629 | 74121 | 32317384 |
Squamous cell carcinoma | 20.06 | 11.48 | 8 | 122013 | 10960 | 32380545 |
Anomaly of external ear congenital | 20.06 | 11.48 | 10 | 122011 | 129 | 32391376 |
Gastric disorder | 19.92 | 11.48 | 9 | 122012 | 11447 | 32380058 |
Cardiac disorder | 19.92 | 11.48 | 85 | 121936 | 41781 | 32349724 |
Adrenal insufficiency | 19.90 | 11.48 | 10 | 122011 | 11958 | 32379547 |
Gingival hypertrophy | 19.81 | 11.48 | 28 | 121993 | 1671 | 32389834 |
Haemangioma | 19.72 | 11.48 | 29 | 121992 | 1795 | 32389710 |
Developmental regression | 19.71 | 11.48 | 7 | 122014 | 35 | 32391470 |
Ehlers-Danlos syndrome | 19.71 | 11.48 | 7 | 122014 | 35 | 32391470 |
Wrong product administered | 19.64 | 11.48 | 52 | 121969 | 4968 | 32386537 |
Ageusia | 19.60 | 11.48 | 6 | 122015 | 9696 | 32381809 |
Poverty of speech | 19.52 | 11.48 | 12 | 122009 | 238 | 32391267 |
Trismus | 19.51 | 11.48 | 35 | 121986 | 2560 | 32388945 |
Kyphosis congenital | 19.50 | 11.48 | 5 | 122016 | 5 | 32391500 |
Incoherent | 19.49 | 11.48 | 48 | 121973 | 4386 | 32387119 |
Hyperexplexia | 19.39 | 11.48 | 7 | 122014 | 37 | 32391468 |
Pneumonia bacterial | 19.30 | 11.48 | 8 | 122013 | 10708 | 32380797 |
IVth nerve disorder | 19.28 | 11.48 | 6 | 122015 | 18 | 32391487 |
Limb discomfort | 19.25 | 11.48 | 7 | 122014 | 10147 | 32381358 |
Hostility | 19.19 | 11.48 | 20 | 122001 | 867 | 32390638 |
Feeling hot | 19.19 | 11.48 | 21 | 122000 | 16865 | 32374640 |
Micrognathia | 19.17 | 11.48 | 13 | 122008 | 307 | 32391198 |
Immune reconstitution inflammatory syndrome | 19.15 | 11.48 | 6 | 122015 | 9553 | 32381952 |
Hyperhomocysteinaemia | 19.13 | 11.48 | 11 | 122010 | 192 | 32391313 |
Otitis media | 19.09 | 11.48 | 36 | 121985 | 2737 | 32388768 |
Cardiogenic shock | 19.06 | 11.48 | 30 | 121991 | 20632 | 32370873 |
Myelosuppression | 19.05 | 11.48 | 10 | 122011 | 11666 | 32379839 |
Iris coloboma | 19.04 | 11.48 | 6 | 122015 | 19 | 32391486 |
Pulmonary oedema | 19.04 | 11.48 | 99 | 121922 | 46168 | 32345337 |
Aspiration | 18.97 | 11.48 | 88 | 121933 | 11135 | 32380370 |
Rhabdomyolysis | 18.86 | 11.48 | 356 | 121665 | 66909 | 32324596 |
Failure to suspend medication | 18.84 | 11.48 | 13 | 122008 | 316 | 32391189 |
Skin cancer | 18.75 | 11.48 | 5 | 122016 | 8845 | 32382660 |
Tonsillitis | 18.73 | 11.48 | 31 | 121990 | 2125 | 32389380 |
Phimosis | 18.71 | 11.48 | 18 | 122003 | 708 | 32390797 |
Blood lactic acid increased | 18.71 | 11.48 | 59 | 121962 | 6222 | 32385283 |
Cerebral infarction | 18.70 | 11.48 | 48 | 121973 | 27566 | 32363939 |
Gastric ulcer | 18.70 | 11.48 | 19 | 122002 | 15790 | 32375715 |
Lower gastrointestinal haemorrhage | 18.64 | 11.48 | 5 | 122016 | 8812 | 32382693 |
Aura | 18.63 | 11.48 | 13 | 122008 | 322 | 32391183 |
Intermittent explosive disorder | 18.59 | 11.48 | 5 | 122016 | 7 | 32391498 |
Polydipsia | 18.59 | 11.48 | 43 | 121978 | 3774 | 32387731 |
Pleural effusion | 18.58 | 11.48 | 198 | 121823 | 78794 | 32312711 |
Coma blister | 18.56 | 11.48 | 8 | 122013 | 72 | 32391433 |
Verbal abuse | 18.50 | 11.48 | 11 | 122010 | 205 | 32391300 |
Maternal drugs affecting foetus | 18.49 | 11.48 | 46 | 121975 | 4231 | 32387274 |
Agranulocytosis | 18.47 | 11.48 | 151 | 121870 | 23326 | 32368179 |
Poor sucking reflex | 18.45 | 11.48 | 13 | 122008 | 327 | 32391178 |
Jaundice | 18.39 | 11.48 | 66 | 121955 | 34092 | 32357413 |
Refraction disorder | 18.37 | 11.48 | 6 | 122015 | 22 | 32391483 |
Ear, nose and throat examination abnormal | 18.36 | 11.48 | 4 | 122017 | 0 | 32391505 |
Retracted nipple | 18.36 | 11.48 | 4 | 122017 | 0 | 32391505 |
Laryngeal web | 18.36 | 11.48 | 4 | 122017 | 0 | 32391505 |
Blood pressure systolic increased | 18.30 | 11.48 | 23 | 121998 | 17373 | 32374132 |
Squamous cell carcinoma of skin | 18.25 | 11.48 | 7 | 122014 | 9819 | 32381686 |
Resting tremor | 18.22 | 11.48 | 17 | 122004 | 643 | 32390862 |
Graft versus host disease | 18.01 | 11.48 | 9 | 122012 | 10797 | 32380708 |
Craniofacial deformity | 18.01 | 11.48 | 8 | 122013 | 78 | 32391427 |
Venoocclusive liver disease | 17.98 | 11.48 | 3 | 122018 | 7362 | 32384143 |
School refusal | 17.97 | 11.48 | 6 | 122015 | 24 | 32391481 |
Compensatory sweating | 17.97 | 11.48 | 6 | 122015 | 24 | 32391481 |
Febrile convulsion | 17.91 | 11.48 | 16 | 122005 | 572 | 32390933 |
Necrotising colitis | 17.90 | 11.48 | 21 | 122000 | 1040 | 32390465 |
Lennox-Gastaut syndrome | 17.87 | 11.48 | 7 | 122014 | 48 | 32391457 |
Pasteurella infection | 17.83 | 11.48 | 5 | 122016 | 9 | 32391496 |
Cholelithiasis | 17.78 | 11.48 | 32 | 121989 | 20880 | 32370625 |
Simple partial seizures | 17.78 | 11.48 | 12 | 122009 | 281 | 32391224 |
Intestinal ischaemia | 17.75 | 11.48 | 64 | 121957 | 7227 | 32384278 |
Dementia with Lewy bodies | 17.66 | 11.48 | 17 | 122004 | 669 | 32390836 |
Hepatic function abnormal | 17.66 | 11.48 | 251 | 121770 | 44589 | 32346916 |
Supernumerary nipple | 17.63 | 11.48 | 7 | 122014 | 50 | 32391455 |
Conjunctival hyperaemia | 17.60 | 11.48 | 32 | 121989 | 2366 | 32389139 |
Hypoxia | 17.51 | 11.48 | 119 | 121902 | 52013 | 32339492 |
Thought blocking | 17.47 | 11.48 | 9 | 122012 | 125 | 32391380 |
Large intestine polyp | 17.45 | 11.48 | 3 | 122018 | 7203 | 32384302 |
Hepatitis C virus test positive | 17.38 | 11.48 | 14 | 122007 | 433 | 32391072 |
Hypokinesia | 17.35 | 11.48 | 70 | 121951 | 8335 | 32383170 |
Oral candidiasis | 17.24 | 11.48 | 12 | 122009 | 12015 | 32379490 |
Blood glucose increased | 17.23 | 11.48 | 159 | 121862 | 65082 | 32326423 |
MELAS syndrome | 17.23 | 11.48 | 6 | 122015 | 28 | 32391477 |
Diverticulitis | 17.20 | 11.48 | 28 | 121993 | 19000 | 32372505 |
Cataract | 17.19 | 11.48 | 41 | 121980 | 24142 | 32367363 |
Conversion disorder | 17.19 | 11.48 | 13 | 122008 | 366 | 32391139 |
Epileptic aura | 17.17 | 11.48 | 5 | 122016 | 11 | 32391494 |
Contusion | 17.15 | 11.48 | 66 | 121955 | 33402 | 32358103 |
Frequent bowel movements | 17.12 | 11.48 | 7 | 122014 | 9445 | 32382060 |
Adenoidectomy | 17.08 | 11.48 | 8 | 122013 | 89 | 32391416 |
Presyncope | 17.05 | 11.48 | 24 | 121997 | 17277 | 32374228 |
Brachydactyly | 16.98 | 11.48 | 10 | 122011 | 183 | 32391322 |
Social problem | 16.96 | 11.48 | 19 | 122002 | 895 | 32390610 |
Withdrawal syndrome | 16.90 | 11.48 | 90 | 121931 | 12032 | 32379473 |
Mixed delusion | 16.87 | 11.48 | 5 | 122016 | 12 | 32391493 |
Suspiciousness | 16.83 | 11.48 | 13 | 122008 | 378 | 32391127 |
Automatism | 16.78 | 11.48 | 8 | 122013 | 93 | 32391412 |
Neutrophil Pelger-Huet anomaly present | 16.70 | 11.48 | 11 | 122010 | 247 | 32391258 |
Tendonitis | 16.60 | 11.48 | 6 | 122015 | 8729 | 32382776 |
Lymphoma | 16.54 | 11.48 | 10 | 122011 | 10790 | 32380715 |
Neutropenic sepsis | 16.51 | 11.48 | 14 | 122007 | 12685 | 32378820 |
Dermatitis | 16.50 | 11.48 | 6 | 122015 | 8698 | 32382807 |
Body dysmorphic disorder | 16.48 | 11.48 | 8 | 122013 | 97 | 32391408 |
Dyspepsia | 16.42 | 11.48 | 66 | 121955 | 32989 | 32358516 |
Product administered to patient of inappropriate age | 16.38 | 11.48 | 34 | 121987 | 2772 | 32388733 |
Pain in jaw | 16.32 | 11.48 | 14 | 122007 | 12612 | 32378893 |
Schizoaffective disorder bipolar type | 16.24 | 11.48 | 7 | 122014 | 63 | 32391442 |
Brachycephaly | 16.15 | 11.48 | 7 | 122014 | 64 | 32391441 |
Hyperglycinaemia | 16.13 | 11.48 | 4 | 122017 | 3 | 32391502 |
Sperm concentration decreased | 16.13 | 11.48 | 9 | 122012 | 148 | 32391357 |
Neurological decompensation | 16.12 | 11.48 | 33 | 121988 | 2665 | 32388840 |
Skin exfoliation | 16.08 | 11.48 | 45 | 121976 | 25112 | 32366393 |
Screaming | 16.04 | 11.48 | 23 | 121998 | 1391 | 32390114 |
Meningomyelocele | 15.98 | 11.48 | 10 | 122011 | 205 | 32391300 |
Toxic epidermal necrolysis | 15.96 | 11.48 | 132 | 121889 | 20461 | 32371044 |
Injection site swelling | 15.95 | 11.48 | 8 | 122013 | 9576 | 32381929 |
Hepatic cirrhosis | 15.90 | 11.48 | 24 | 121997 | 16785 | 32374720 |
Opsoclonus myoclonus | 15.87 | 11.48 | 7 | 122014 | 67 | 32391438 |
Enterocolitis | 15.83 | 11.48 | 4 | 122017 | 7336 | 32384169 |
Erectile dysfunction | 15.82 | 11.48 | 128 | 121893 | 19711 | 32371794 |
Hyporeflexia | 15.80 | 11.48 | 28 | 121993 | 2029 | 32389476 |
Irregular sleep phase | 15.78 | 11.48 | 7 | 122014 | 68 | 32391437 |
Wrist deformity | 15.77 | 11.48 | 12 | 122009 | 341 | 32391164 |
Coronary artery occlusion | 15.76 | 11.48 | 12 | 122009 | 11473 | 32380032 |
Retinogram abnormal | 15.72 | 11.48 | 8 | 122013 | 108 | 32391397 |
Haemorrhoids | 15.72 | 11.48 | 15 | 122006 | 12838 | 32378667 |
Muscle twitching | 15.68 | 11.48 | 70 | 121951 | 8714 | 32382791 |
Oral mucosa erosion | 15.64 | 11.48 | 18 | 122003 | 873 | 32390632 |
Abnormal labour affecting foetus | 15.60 | 11.48 | 5 | 122016 | 17 | 32391488 |
Epileptic psychosis | 15.60 | 11.48 | 5 | 122016 | 17 | 32391488 |
Nephrogenic diabetes insipidus | 15.52 | 11.48 | 22 | 121999 | 1316 | 32390189 |
Drug level fluctuating | 15.52 | 11.48 | 14 | 122007 | 507 | 32390998 |
Cardiac failure chronic | 15.51 | 11.48 | 4 | 122017 | 7236 | 32384269 |
Use of accessory respiratory muscles | 15.50 | 11.48 | 12 | 122009 | 350 | 32391155 |
Apparent life threatening event | 15.48 | 11.48 | 10 | 122011 | 217 | 32391288 |
Excessive masturbation | 15.41 | 11.48 | 8 | 122013 | 113 | 32391392 |
Reproductive tract hypoplasia, male | 15.38 | 11.48 | 5 | 122016 | 18 | 32391487 |
Colon cancer | 15.36 | 11.48 | 7 | 122014 | 8859 | 32382646 |
Syndactyly | 15.36 | 11.48 | 17 | 122004 | 790 | 32390715 |
Throat tightness | 15.33 | 11.48 | 5 | 122016 | 7761 | 32383744 |
Acute pulmonary oedema | 15.26 | 11.48 | 5 | 122016 | 7736 | 32383769 |
Electrocardiogram QT prolonged | 15.26 | 11.48 | 221 | 121800 | 39420 | 32352085 |
Peripheral sensory neuropathy | 15.16 | 11.48 | 3 | 122018 | 6511 | 32384994 |
Wheezing | 15.11 | 11.48 | 79 | 121942 | 36795 | 32354710 |
Postural tremor | 15.07 | 11.48 | 12 | 122009 | 365 | 32391140 |
Hepatocellular carcinoma | 15.05 | 11.48 | 10 | 122011 | 10260 | 32381245 |
Poor quality sleep | 14.91 | 11.48 | 65 | 121956 | 8009 | 32383496 |
Skin ulcer | 14.91 | 11.48 | 35 | 121986 | 20724 | 32370781 |
Rebound psychosis | 14.89 | 11.48 | 9 | 122012 | 173 | 32391332 |
Suspected suicide attempt | 14.87 | 11.48 | 8 | 122013 | 122 | 32391383 |
Aphasia | 14.82 | 11.48 | 131 | 121890 | 20697 | 32370808 |
Cardiac failure acute | 14.82 | 11.48 | 10 | 122011 | 10174 | 32381331 |
Injection site erythema | 14.80 | 11.48 | 20 | 122001 | 14648 | 32376857 |
Muscle contracture | 14.80 | 11.48 | 21 | 122000 | 1258 | 32390247 |
Injection site reaction | 14.75 | 11.48 | 13 | 122008 | 11556 | 32379949 |
Psychomotor disadaptation syndrome | 14.71 | 11.48 | 4 | 122017 | 6 | 32391499 |
Contraindicated product administered | 14.65 | 11.48 | 31 | 121990 | 19045 | 32372460 |
Gingival atrophy | 14.64 | 11.48 | 6 | 122015 | 47 | 32391458 |
C-reactive protein abnormal | 14.64 | 11.48 | 3 | 122018 | 6353 | 32385152 |
Hepatitis B | 14.59 | 11.48 | 3 | 122018 | 6338 | 32385167 |
Abnormal palmar/plantar creases | 14.57 | 11.48 | 10 | 122011 | 241 | 32391264 |
Camptocormia | 14.53 | 11.48 | 9 | 122012 | 181 | 32391324 |
Clonic convulsion | 14.51 | 11.48 | 15 | 122006 | 644 | 32390861 |
Wrong technique in product usage process | 14.43 | 11.48 | 75 | 121946 | 34984 | 32356521 |
Partial seizures with secondary generalisation | 14.42 | 11.48 | 10 | 122011 | 245 | 32391260 |
Disseminated intravascular coagulation | 14.41 | 11.48 | 42 | 121979 | 23134 | 32368371 |
Myocardial ischaemia | 14.37 | 11.48 | 28 | 121993 | 17731 | 32373774 |
Chromaturia | 14.35 | 11.48 | 20 | 122001 | 14458 | 32377047 |
Hypothyroidism | 14.35 | 11.48 | 111 | 121910 | 16864 | 32374641 |
Heterophoria | 14.32 | 11.48 | 6 | 122015 | 50 | 32391455 |
Wound | 14.28 | 11.48 | 17 | 122004 | 13150 | 32378355 |
Embolism | 14.24 | 11.48 | 5 | 122016 | 7409 | 32384096 |
Diarrhoea haemorrhagic | 14.24 | 11.48 | 3 | 122018 | 6232 | 32385273 |
Fungal infection | 14.22 | 11.48 | 22 | 121999 | 15233 | 32376272 |
Drug resistance | 14.12 | 11.48 | 140 | 121881 | 22825 | 32368680 |
Agitation neonatal | 14.11 | 11.48 | 19 | 122002 | 1083 | 32390422 |
Hypomagnesaemia | 14.08 | 11.48 | 31 | 121990 | 18774 | 32372731 |
Kyphosis | 14.03 | 11.48 | 19 | 122002 | 1089 | 32390416 |
Pulmonary valve incompetence | 14.02 | 11.48 | 16 | 122005 | 769 | 32390736 |
Anamnestic reaction | 14.02 | 11.48 | 6 | 122015 | 53 | 32391452 |
Device issue | 14.01 | 11.48 | 8 | 122013 | 8904 | 32382601 |
Ischaemic stroke | 13.98 | 11.48 | 28 | 121993 | 17548 | 32373957 |
Hallucination | 13.90 | 11.48 | 276 | 121745 | 52343 | 32339162 |
Hyperthyroidism | 13.88 | 11.48 | 9 | 122012 | 9353 | 32382152 |
Cardiovascular disorder | 13.83 | 11.48 | 12 | 122009 | 10750 | 32380755 |
Cerebral cyst | 13.81 | 11.48 | 10 | 122011 | 263 | 32391242 |
Enteritis | 13.77 | 11.48 | 5 | 122016 | 7256 | 32384249 |
Dacryoadenitis acquired | 13.77 | 11.48 | 3 | 122018 | 0 | 32391505 |
Acquired epileptic aphasia | 13.77 | 11.48 | 3 | 122018 | 0 | 32391505 |
Hypocarnitinaemia | 13.77 | 11.48 | 3 | 122018 | 0 | 32391505 |
Mentally late developer | 13.77 | 11.48 | 3 | 122018 | 0 | 32391505 |
Dentofacial anomaly | 13.77 | 11.48 | 3 | 122018 | 0 | 32391505 |
Blindness congenital | 13.77 | 11.48 | 3 | 122018 | 0 | 32391505 |
Renal fusion anomaly | 13.77 | 11.48 | 3 | 122018 | 0 | 32391505 |
Reduced facial expression | 13.76 | 11.48 | 17 | 122004 | 889 | 32390616 |
Hyperreflexia | 13.72 | 11.48 | 33 | 121988 | 2971 | 32388534 |
Pancreatic carcinoma | 13.72 | 11.48 | 7 | 122014 | 8299 | 32383206 |
Congenital nipple anomaly | 13.68 | 11.48 | 4 | 122017 | 9 | 32391496 |
Elbow deformity | 13.68 | 11.48 | 4 | 122017 | 9 | 32391496 |
Osteonecrosis | 13.63 | 11.48 | 26 | 121995 | 16596 | 32374909 |
Sinus disorder | 13.62 | 11.48 | 4 | 122017 | 6640 | 32384865 |
Septum pellucidum agenesis | 13.62 | 11.48 | 5 | 122016 | 28 | 32391477 |
CSF white blood cell count positive | 13.62 | 11.48 | 5 | 122016 | 28 | 32391477 |
Frontotemporal dementia | 13.58 | 11.48 | 10 | 122011 | 270 | 32391235 |
Dysphagia | 13.52 | 11.48 | 314 | 121707 | 61162 | 32330343 |
Pancreatitis haemorrhagic | 13.47 | 11.48 | 11 | 122010 | 347 | 32391158 |
Niemann-Pick disease | 13.46 | 11.48 | 6 | 122015 | 59 | 32391446 |
Heart rate irregular | 13.41 | 11.48 | 20 | 122001 | 14058 | 32377447 |
Spinal fracture | 13.33 | 11.48 | 5 | 122016 | 7111 | 32384394 |
Mental disability | 13.33 | 11.48 | 5 | 122016 | 30 | 32391475 |
Posterior reversible encephalopathy syndrome | 13.29 | 11.48 | 71 | 121950 | 9505 | 32382000 |
Adverse drug reaction | 13.25 | 11.48 | 51 | 121970 | 25810 | 32365695 |
Hip fracture | 13.24 | 11.48 | 15 | 122006 | 11860 | 32379645 |
Mastication disorder | 13.20 | 11.48 | 20 | 122001 | 1271 | 32390234 |
Bronchospasm | 13.15 | 11.48 | 13 | 122008 | 10942 | 32380563 |
Laryngitis | 13.12 | 11.48 | 27 | 121994 | 2188 | 32389317 |
Hand-eye coordination impaired | 13.12 | 11.48 | 6 | 122015 | 63 | 32391442 |
Feeding disorder | 13.11 | 11.48 | 54 | 121967 | 6491 | 32385014 |
Haemorrhagic stroke | 13.10 | 11.48 | 4 | 122017 | 6474 | 32385031 |
Ankyloglossia congenital | 13.06 | 11.48 | 10 | 122011 | 287 | 32391218 |
Back disorder | 13.05 | 11.48 | 4 | 122017 | 6459 | 32385046 |
Maternal exposure during pregnancy | 13.04 | 11.48 | 41 | 121980 | 4316 | 32387189 |
Dependent personality disorder | 13.03 | 11.48 | 6 | 122015 | 64 | 32391441 |
Congenital genital malformation | 13.03 | 11.48 | 6 | 122015 | 64 | 32391441 |
Myopathy | 13.00 | 11.48 | 14 | 122007 | 11327 | 32380178 |
Arachnoid cyst | 13.00 | 11.48 | 9 | 122012 | 220 | 32391285 |
Heat stroke | 12.99 | 11.48 | 17 | 122004 | 942 | 32390563 |
Ischaemic cardiomyopathy | 12.96 | 11.48 | 4 | 122017 | 6430 | 32385075 |
Respiratory fatigue | 12.87 | 11.48 | 6 | 122015 | 66 | 32391439 |
Monorchidism | 12.86 | 11.48 | 4 | 122017 | 12 | 32391493 |
Congenital cerebral cyst | 12.86 | 11.48 | 4 | 122017 | 12 | 32391493 |
Locomotive syndrome | 12.86 | 11.48 | 4 | 122017 | 12 | 32391493 |
Delayed fontanelle closure | 12.80 | 11.48 | 5 | 122016 | 34 | 32391471 |
Malocclusion | 12.79 | 11.48 | 6 | 122015 | 67 | 32391438 |
Vasoplegia syndrome | 12.76 | 11.48 | 21 | 122000 | 1433 | 32390072 |
Small intestinal obstruction | 12.73 | 11.48 | 21 | 122000 | 14175 | 32377330 |
Terminal insomnia | 12.69 | 11.48 | 12 | 122009 | 462 | 32391043 |
Pulmonary thrombosis | 12.69 | 11.48 | 5 | 122016 | 6899 | 32384606 |
Pulmonary haemorrhage | 12.65 | 11.48 | 11 | 122010 | 9846 | 32381659 |
Joint hyperextension | 12.64 | 11.48 | 6 | 122015 | 69 | 32391436 |
Anticoagulation drug level decreased | 12.64 | 11.48 | 6 | 122015 | 69 | 32391436 |
Blunted affect | 12.62 | 11.48 | 10 | 122011 | 302 | 32391203 |
Cardiac murmur | 12.61 | 11.48 | 57 | 121964 | 7134 | 32384371 |
Metastases to lung | 12.60 | 11.48 | 8 | 122013 | 8409 | 32383096 |
Feminisation acquired | 12.56 | 11.48 | 5 | 122016 | 36 | 32391469 |
Therapeutic response changed | 12.55 | 11.48 | 11 | 122010 | 383 | 32391122 |
Heparin-induced thrombocytopenia | 12.55 | 11.48 | 3 | 122018 | 5711 | 32385794 |
Hypovolaemia | 12.54 | 11.48 | 9 | 122012 | 8868 | 32382637 |
Intestinal perforation | 12.53 | 11.48 | 9 | 122012 | 8866 | 32382639 |
Blood alkaline phosphatase increased | 12.53 | 11.48 | 70 | 121951 | 32062 | 32359443 |
Coronary artery stenosis | 12.49 | 11.48 | 11 | 122010 | 9782 | 32381723 |
Gender dysphoria | 12.44 | 11.48 | 5 | 122016 | 37 | 32391468 |
Cholangitis | 12.44 | 11.48 | 8 | 122013 | 8350 | 32383155 |
Polyserositis | 12.41 | 11.48 | 8 | 122013 | 173 | 32391332 |
Glomerular filtration rate decreased | 12.40 | 11.48 | 18 | 122003 | 12793 | 32378712 |
Hypotony maculopathy | 12.39 | 11.48 | 4 | 122017 | 14 | 32391491 |
Nocturia | 12.39 | 11.48 | 10 | 122011 | 9284 | 32382221 |
Pulmonary eosinophilia | 12.35 | 11.48 | 9 | 122012 | 239 | 32391266 |
Intentional product misuse | 12.33 | 11.48 | 197 | 121824 | 35854 | 32355651 |
Haematoma | 12.31 | 11.48 | 52 | 121969 | 25632 | 32365873 |
Gallbladder disorder | 12.28 | 11.48 | 4 | 122017 | 6213 | 32385292 |
Accidental death | 12.27 | 11.48 | 26 | 121995 | 2151 | 32389354 |
Slow response to stimuli | 12.27 | 11.48 | 15 | 122006 | 776 | 32390729 |
Anxiety disorder | 12.22 | 11.48 | 22 | 121999 | 1614 | 32389891 |
Urosepsis | 12.22 | 11.48 | 16 | 122005 | 11874 | 32379631 |
Pica | 12.18 | 11.48 | 4 | 122017 | 15 | 32391490 |
Brain stem auditory evoked response abnormal | 12.18 | 11.48 | 4 | 122017 | 15 | 32391490 |
Feeling of despair | 12.17 | 11.48 | 17 | 122004 | 1003 | 32390502 |
Eating disorder | 12.14 | 11.48 | 59 | 121962 | 7609 | 32383896 |
Neutropenia | 12.12 | 11.48 | 651 | 121370 | 141524 | 32249981 |
Cytotoxic oedema | 12.09 | 11.48 | 8 | 122013 | 181 | 32391324 |
Snoring | 12.06 | 11.48 | 32 | 121989 | 3061 | 32388444 |
Haemorrhage intracranial | 12.05 | 11.48 | 26 | 121995 | 15861 | 32375644 |
Hypercalcaemia | 12.05 | 11.48 | 21 | 122000 | 13873 | 32377632 |
Sudden death | 12.02 | 11.48 | 103 | 121918 | 16129 | 32375376 |
Cytopenia | 12.01 | 11.48 | 12 | 122009 | 10052 | 32381453 |
Polydipsia psychogenic | 11.99 | 11.48 | 7 | 122014 | 126 | 32391379 |
Mass | 11.95 | 11.48 | 7 | 122014 | 7685 | 32383820 |
Infertility male | 11.94 | 11.48 | 8 | 122013 | 185 | 32391320 |
Diabetic coma | 11.92 | 11.48 | 16 | 122005 | 909 | 32390596 |
Injection site pruritus | 11.89 | 11.48 | 4 | 122017 | 6086 | 32385419 |
Gastritis | 11.87 | 11.48 | 42 | 121979 | 21785 | 32369720 |
Congenital inguinal hernia | 11.84 | 11.48 | 7 | 122014 | 129 | 32391376 |
Myoglobin urine present | 11.83 | 11.48 | 8 | 122013 | 188 | 32391317 |
Urine output decreased | 11.83 | 11.48 | 13 | 122008 | 10421 | 32381084 |
Progressive multifocal leukoencephalopathy | 11.80 | 11.48 | 11 | 122010 | 9520 | 32381985 |
Kidney malformation | 11.79 | 11.48 | 8 | 122013 | 189 | 32391316 |
Poisoning | 11.78 | 11.48 | 77 | 121944 | 11081 | 32380424 |
Abulia | 11.73 | 11.48 | 12 | 122009 | 509 | 32390996 |
Illusion | 11.72 | 11.48 | 15 | 122006 | 813 | 32390692 |
Congenital cardiovascular anomaly | 11.72 | 11.48 | 8 | 122013 | 191 | 32391314 |
Mitochondrial DNA mutation | 11.70 | 11.48 | 3 | 122018 | 3 | 32391502 |
Near drowning | 11.70 | 11.48 | 3 | 122018 | 3 | 32391502 |
Kluver-Bucy syndrome | 11.70 | 11.48 | 3 | 122018 | 3 | 32391502 |
Nasopharyngeal reflux | 11.70 | 11.48 | 3 | 122018 | 3 | 32391502 |
Post-anoxic myoclonus | 11.70 | 11.48 | 3 | 122018 | 3 | 32391502 |
Drowning | 11.68 | 11.48 | 11 | 122010 | 421 | 32391084 |
Therapy interrupted | 11.66 | 11.48 | 8 | 122013 | 8070 | 32383435 |
Cyanosis central | 11.65 | 11.48 | 7 | 122014 | 133 | 32391372 |
Skin lesion | 11.65 | 11.48 | 38 | 121983 | 20203 | 32371302 |
Vanishing bile duct syndrome | 11.64 | 11.48 | 14 | 122007 | 712 | 32390793 |
Infertility | 11.57 | 11.48 | 8 | 122013 | 195 | 32391310 |
Source | Code | Description |
---|---|---|
ATC | N03AG01 | NERVOUS SYSTEM ANTIEPILEPTICS ANTIEPILEPTICS Fatty acid derivatives |
FDA PE | N0000008486 | Decreased Central Nervous System Disorganized Electrical Activity |
CHEBI has role | CHEBI:35477 | antimanics |
CHEBI has role | CHEBI:35623 | antiepileptic |
MeSH PA | D000927 | Anticonvulsants |
MeSH PA | D018692 | Antimanic Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D018682 | GABA Agents |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D011619 | Psychotropic Drugs |
MeSH PA | D014149 | Tranquilizing Agents |
CHEBI has role | CHEBI:176497 | anti-aging drugs |
FDA EPC | N0000175751 | Mood Stabilizer |
FDA EPC | N0000175753 | Anti-epileptic Agent |
CHEBI has role | CHEBI:35471 | psychopharmaceuticals |
CHEBI has role | CHEBI:50905 | teratogen |
CHEBI has role | CHEBI:61115 | HDAC inhibitor |
CHEBI has role | CHEBI:63726 | neuroprotective agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Absence seizure | indication | 79631006 | |
Epilepsy | indication | 84757009 | DOID:1826 |
Bipolar affective disorder, current episode manic | indication | 191618007 | |
Epilepsy characterized by intractable complex partial seizures | indication | 442481002 | |
Migraine Prevention | indication | ||
Bipolar disorder | off-label use | 13746004 | DOID:3312 |
Mixed bipolar I disorder | off-label use | 16506000 | DOID:3312 |
Myoclonic seizure | off-label use | 37356005 | |
Bipolar disorder in remission | off-label use | 85248005 | |
Seizure disorder | off-label use | 128613002 | |
Bipolar affective disorder, current episode depression | off-label use | 191627008 | DOID:3312 |
Tonic-clonic epilepsy | off-label use | 352818000 | DOID:7725 |
Simple partial seizure | off-label use | 117891000119100 | |
Rapid Cycling Bipolar Affective Disorder | off-label use | ||
Suicidal thoughts | contraindication | 6471006 | |
Hyperammonemia | contraindication | 9360008 | |
Arginase deficiency | contraindication | 23501004 | DOID:9278 |
Depressive disorder | contraindication | 35489007 | |
Congenital hyperammonemia, type I | contraindication | 62522004 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Organic mental disorder | contraindication | 111479008 | |
Hypoalbuminemia | contraindication | 119247004 | |
Disease of blood AND/OR blood-forming organ | contraindication | 191124002 | DOID:74 |
Acute pancreatitis | contraindication | 197456007 | DOID:2913 |
Chronic pancreatitis | contraindication | 235494005 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Poisoning by sodium valproate | contraindication | 241754000 | |
Pregnancy, function | contraindication | 289908002 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Hypothermia | contraindication | 386689009 | |
Citrullinemia | contraindication | 398680004 | DOID:9273 |
Porphyria | contraindication | 418470004 | |
Ornithine Carbamyltransferase Deficiency | contraindication | ||
Arginosuccinate Lyase Deficiency | contraindication |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.97 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Succinate-semialdehyde dehydrogenase, mitochondrial | Enzyme | INHIBITOR | CHEMBL | CHEMBL | |||||
Histone deacetylase 2 | Enzyme | IC50 | 4.21 | CHEMBL | |||||
Histone deacetylase 1 | Enzyme | INHIBITOR | IC50 | 6.40 | IUPHAR | ||||
Alcohol dehydrogenase [NADP(+)] | Enzyme | IC50 | 4.30 | CHEMBL | |||||
UDP-glucuronosyltransferase 1-5 | Enzyme | WOMBAT-PK | |||||||
Alcohol dehydrogenase [NADP(+)] | Enzyme | IC50 | 4.05 | CHEMBL | |||||
Aldose reductase | Enzyme | IC50 | 4.25 | CHEMBL | |||||
Aldose reductase | Enzyme | IC50 | 4.24 | CHEMBL | |||||
Alcohol dehydrogenase [NADP(+)] | Enzyme | IC50 | 4.30 | CHEMBL | |||||
Aldose reductase-related protein 1 | Enzyme | IC50 | 4.25 | CHEMBL |
ID | Source |
---|---|
4022507 | VUID |
N0000147028 | NUI |
D00304 | KEGG_DRUG |
76584-70-8 | SECONDARY_CAS_RN |
4018723 | VANDF |
4018724 | VANDF |
4018728 | VANDF |
4022507 | VANDF |
C0042291 | UMLSCUI |
CHEBI:39867 | CHEBI |
2PP | PDB_CHEM_ID |
CHEMBL109 | ChEMBL_ID |
DB00313 | DRUGBANK_ID |
CHEMBL2105613 | ChEMBL_ID |
CHEMBL433 | ChEMBL_ID |
D014635 | MESH_DESCRIPTOR_UI |
3121 | PUBCHEM_CID |
3300 | INN_ID |
7009 | IUPHAR_LIGAND_ID |
5132 | INN_ID |
614OI1Z5WI | UNII |
11118 | RXNORM |
147344 | MMSL |
17039 | MMSL |
203066 | MMSL |
255547 | MMSL |
3118 | MMSL |
4624 | MMSL |
5661 | MMSL |
5662 | MMSL |
942 | MMSL |
d00083 | MMSL |
d03833 | MMSL |
001622 | NDDF |
001623 | NDDF |
001624 | NDDF |
006036 | NDDF |
007107 | NDDF |
13965000 | SNOMEDCT_US |
387080000 | SNOMEDCT_US |
387481005 | SNOMEDCT_US |
5641004 | SNOMEDCT_US |
CHEMBL2315212 | ChEMBL_ID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-3826 | TABLET, EXTENDED RELEASE | 250 mg | ORAL | NDA | 31 sections |
DepakoteSprinkles | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6114 | CAPSULE | 125 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6212 | TABLET, DELAYED RELEASE | 125 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6214 | TABLET, DELAYED RELEASE | 250 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6215 | TABLET, DELAYED RELEASE | 500 mg | ORAL | NDA | 31 sections |
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7126 | TABLET, EXTENDED RELEASE | 500 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7325 | TABLET, DELAYED RELEASE | 125 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7327 | TABLET, DELAYED RELEASE | 500 mg | ORAL | NDA | 31 sections |
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7402 | TABLET, EXTENDED RELEASE | 500 mg | ORAL | NDA | 31 sections |
VALPROIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-0675 | SOLUTION | 250 mg | ORAL | ANDA | 31 sections |
VALPROIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-1350 | SOLUTION | 500 mg | ORAL | ANDA | 31 sections |
VALPROIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-4675 | SOLUTION | 250 mg | ORAL | ANDA | 31 sections |
Valproate Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9637 | INJECTION | 100 mg | INTRAVENOUS | ANDA | 27 sections |
Valproate Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9785 | INJECTION | 500 mg | INTRAVENOUS | ANDA | 29 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0472 | TABLET, FILM COATED, EXTENDED RELEASE | 250 mg | ORAL | ANDA | 29 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0473 | TABLET, FILM COATED, EXTENDED RELEASE | 500 mg | ORAL | ANDA | 29 sections |
VALPROIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-5250 | SOLUTION | 250 mg | ORAL | ANDA | 30 sections |
Valproic | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0591-4012 | CAPSULE, LIQUID FILLED | 250 mg | ORAL | ANDA | 29 sections |
Valproic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-1325 | CAPSULE | 250 mg | ORAL | ANDA | 24 sections |
Valproic | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7840 | CAPSULE, LIQUID FILLED | 250 mg | ORAL | ANDA | 27 sections |
Valproic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8205 | CAPSULE, LIQUID FILLED | 250 mg | ORAL | ANDA | 23 sections |
Divalproex sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8237 | CAPSULE | 125 mg | ORAL | ANDA | 28 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8326 | TABLET, DELAYED RELEASE | 125 mg | ORAL | ANDA | 31 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8327 | TABLET, DELAYED RELEASE | 250 mg | ORAL | ANDA | 31 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8328 | TABLET, DELAYED RELEASE | 500 mg | ORAL | ANDA | 31 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8329 | TABLET, EXTENDED RELEASE | 250 mg | ORAL | ANDA | 28 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8330 | TABLET, EXTENDED RELEASE | 500 mg | ORAL | ANDA | 28 sections |
Divalproex sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8376 | TABLET, EXTENDED RELEASE | 250 mg | ORAL | ANDA | 28 sections |
Divalproex sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8377 | TABLET, EXTENDED RELEASE | 500 mg | ORAL | ANDA | 28 sections |
valproic acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-0310 | CAPSULE | 250 mg | ORAL | ANDA | 30 sections |