sulfisomidine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-infectives, sulfonamides 2526 515-64-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • sulfasomidine
  • sulfadimetine
  • sulfaisodimerazine
  • sulfamethine
  • sulfasomidin
  • sulfisomidin
  • sulfisomidine
  • sulphasomidine
  • sulphisomidine
  • sulfaisodimidine
A sulfanilamide antibacterial agent.
  • Molecular weight: 278.33
  • Formula: C12H14N4O2S
  • CLOGP: 1.10
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 97.97
  • ALOGS: -3.09
  • ROTB: 2

Drug dosage:

DoseUnitRoute
4 g O
4 g P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01EB01 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
SULFONAMIDES AND TRIMETHOPRIM
Short-acting sulfonamides
MeSH PA D000890 Anti-Infective Agents
CHEBI has role CHEBI:35441 antiinfective agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.21 acidic
pKa2 4.49 Basic
pKa3 2.24 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Protein argonaute-2 Unclassified Kd 5.37 CHEMBL

External reference:

IDSource
N0000166865 NUI
D01526 KEGG_DRUG
CHEBI:32166 CHEBI
CHEMBL485696 ChEMBL_ID
99 INN_ID
DB13283 DRUGBANK_ID
W03L3ODK6E UNII
5343 PUBCHEM_CID
10206 RXNORM
002823 NDDF
4014000 SNOMEDCT_US
D013443 MESH_DESCRIPTOR_UI
C0038744 UMLSCUI

Pharmaceutical products:

None