Stem definition | Drug id | CAS RN |
---|---|---|
antihyperlipidaemic substances, HMG CoA reductase inhibitors | 2445 | 79902-63-9 |
Dose | Unit | Route |
---|---|---|
30 | mg | O |
30 | mg | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.03 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 10 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 1.37 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 3 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 23, 1991 | FDA | MERCK |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Rhabdomyolysis | 2204.21 | 9.91 | 1619 | 243940 | 42332 | 63201131 |
Myalgia | 968.83 | 9.91 | 1900 | 243659 | 144629 | 63098834 |
Drug interaction | 831.36 | 9.91 | 2349 | 243210 | 226782 | 63016681 |
Drug ineffective | 747.55 | 9.91 | 1860 | 243699 | 1042905 | 62200558 |
Maternal exposure during pregnancy | 644.04 | 9.91 | 56 | 245503 | 220006 | 63023457 |
Blood creatine phosphokinase increased | 611.83 | 9.91 | 669 | 244890 | 29761 | 63213702 |
Systemic lupus erythematosus | 609.10 | 9.91 | 54 | 245505 | 208864 | 63034599 |
Pemphigus | 593.01 | 9.91 | 28 | 245531 | 183698 | 63059765 |
Acute kidney injury | 575.45 | 9.91 | 2276 | 243283 | 261139 | 62982324 |
Hand deformity | 543.05 | 9.91 | 16 | 245543 | 159441 | 63084022 |
Myopathy | 504.30 | 9.91 | 387 | 245172 | 10804 | 63232659 |
Glossodynia | 500.96 | 9.91 | 54 | 245505 | 178822 | 63064641 |
Off label use | 498.32 | 9.91 | 1178 | 244381 | 673284 | 62570179 |
Synovitis | 472.12 | 9.91 | 78 | 245481 | 186840 | 63056623 |
Treatment failure | 458.56 | 9.91 | 104 | 245455 | 198939 | 63044524 |
Contraindicated product administered | 399.17 | 9.91 | 171 | 245388 | 217477 | 63025986 |
Infusion related reaction | 377.79 | 9.91 | 242 | 245317 | 245279 | 62998184 |
Myocardial infarction | 374.07 | 9.91 | 1037 | 244522 | 98856 | 63144607 |
Drug intolerance | 344.75 | 9.91 | 412 | 245147 | 308249 | 62935214 |
Fall | 334.15 | 9.91 | 2626 | 242933 | 389708 | 62853755 |
Product use issue | 328.89 | 9.91 | 225 | 245334 | 220295 | 63023168 |
Therapeutic product effect decreased | 314.51 | 9.91 | 178 | 245381 | 193009 | 63050454 |
Joint swelling | 312.94 | 9.91 | 490 | 245069 | 327176 | 62916287 |
Exposure during pregnancy | 308.62 | 9.91 | 108 | 245451 | 155439 | 63088024 |
Arthropathy | 305.42 | 9.91 | 275 | 245284 | 234517 | 63008946 |
Rheumatoid arthritis | 289.54 | 9.91 | 333 | 245226 | 253486 | 62989977 |
Duodenal ulcer perforation | 288.87 | 9.91 | 11 | 245548 | 87198 | 63156265 |
Discomfort | 287.43 | 9.91 | 144 | 245415 | 167230 | 63076233 |
Hyponatraemia | 275.99 | 9.91 | 1006 | 244553 | 110894 | 63132569 |
Alopecia | 267.59 | 9.91 | 566 | 244993 | 336970 | 62906493 |
Swelling | 266.48 | 9.91 | 408 | 245151 | 274970 | 62968493 |
Coronary artery disease | 265.27 | 9.91 | 461 | 245098 | 31916 | 63211547 |
Wound | 262.03 | 9.91 | 153 | 245406 | 163110 | 63080353 |
Pericarditis | 253.14 | 9.91 | 96 | 245463 | 131483 | 63111980 |
Cerebrovascular accident | 239.76 | 9.91 | 939 | 244620 | 107085 | 63136378 |
Helicobacter infection | 231.31 | 9.91 | 40 | 245519 | 92745 | 63150718 |
Folliculitis | 229.08 | 9.91 | 10 | 245549 | 70307 | 63173156 |
Abdominal discomfort | 223.84 | 9.91 | 576 | 244983 | 320309 | 62923154 |
Syncope | 217.16 | 9.91 | 965 | 244594 | 116420 | 63127043 |
Muscular weakness | 207.90 | 9.91 | 981 | 244578 | 121372 | 63122091 |
Rheumatoid factor positive | 202.65 | 9.91 | 40 | 245519 | 84366 | 63159097 |
Immune-mediated myositis | 200.97 | 9.91 | 100 | 245459 | 1243 | 63242220 |
Sleep disorder due to general medical condition, insomnia type | 186.41 | 9.91 | 3 | 245556 | 52214 | 63191249 |
Lactic acidosis | 186.33 | 9.91 | 439 | 245120 | 37848 | 63205615 |
Product prescribing error | 185.68 | 9.91 | 351 | 245208 | 25938 | 63217525 |
Nasopharyngitis | 185.34 | 9.91 | 446 | 245113 | 253811 | 62989652 |
Hypoglycaemia | 180.48 | 9.91 | 577 | 244982 | 59488 | 63183975 |
Transient ischaemic attack | 179.53 | 9.91 | 429 | 245130 | 37324 | 63206139 |
Atrial fibrillation | 178.70 | 9.91 | 908 | 244651 | 115728 | 63127735 |
Myositis | 178.04 | 9.91 | 199 | 245360 | 9067 | 63234396 |
Hypersensitivity | 177.85 | 9.91 | 561 | 244998 | 292124 | 62951339 |
Hepatic enzyme increased | 176.83 | 9.91 | 320 | 245239 | 202008 | 63041455 |
Dizziness | 175.55 | 9.91 | 2480 | 243079 | 427445 | 62816018 |
Condition aggravated | 175.23 | 9.91 | 880 | 244679 | 401337 | 62842126 |
Labelled drug-drug interaction medication error | 166.13 | 9.91 | 231 | 245328 | 13168 | 63230295 |
Infection | 164.63 | 9.91 | 405 | 245154 | 228768 | 63014695 |
International normalised ratio increased | 156.24 | 9.91 | 464 | 245095 | 45961 | 63197502 |
Gastrointestinal haemorrhage | 155.89 | 9.91 | 675 | 244884 | 80501 | 63162962 |
Renal failure | 155.13 | 9.91 | 879 | 244680 | 116773 | 63126690 |
Hyperkalaemia | 150.56 | 9.91 | 507 | 245052 | 53696 | 63189767 |
C-reactive protein abnormal | 148.69 | 9.91 | 7 | 245552 | 46089 | 63197374 |
Angioedema | 147.04 | 9.91 | 464 | 245095 | 47501 | 63195962 |
Muscle injury | 144.74 | 9.91 | 37 | 245522 | 65308 | 63178155 |
Product use in unapproved indication | 141.93 | 9.91 | 300 | 245259 | 178780 | 63064683 |
Pain | 136.56 | 9.91 | 2031 | 243528 | 738597 | 62504866 |
Rash | 132.62 | 9.91 | 1459 | 244100 | 559412 | 62684051 |
Irritable bowel syndrome | 128.27 | 9.91 | 80 | 245479 | 82332 | 63161131 |
Psoriatic arthropathy | 127.70 | 9.91 | 100 | 245459 | 91420 | 63152043 |
Intentional product use issue | 125.94 | 9.91 | 187 | 245372 | 127705 | 63115758 |
Asthenia | 124.37 | 9.91 | 2129 | 243430 | 381475 | 62861988 |
Stomatitis | 119.73 | 9.91 | 221 | 245338 | 138504 | 63104959 |
Product monitoring error | 119.22 | 9.91 | 115 | 245444 | 4401 | 63239062 |
Cardiac failure congestive | 118.16 | 9.91 | 685 | 244874 | 91748 | 63151715 |
Lower respiratory tract infection | 116.66 | 9.91 | 208 | 245351 | 132099 | 63111364 |
Acute myocardial infarction | 115.71 | 9.91 | 329 | 245230 | 31795 | 63211668 |
Abortion spontaneous | 114.04 | 9.91 | 22 | 245537 | 47173 | 63196290 |
Device expulsion | 110.42 | 9.91 | 6 | 245553 | 34916 | 63208547 |
Sinusitis | 109.67 | 9.91 | 477 | 245082 | 226176 | 63017287 |
Dehydration | 106.64 | 9.91 | 1082 | 244477 | 172272 | 63071191 |
Chest pain | 103.78 | 9.91 | 1284 | 244275 | 214675 | 63028788 |
Therapeutic product effect incomplete | 102.01 | 9.91 | 206 | 245353 | 124850 | 63118613 |
Blood glucose increased | 100.81 | 9.91 | 611 | 244948 | 83145 | 63160318 |
Gastrointestinal disorder | 100.52 | 9.91 | 224 | 245335 | 131015 | 63112448 |
Liver function test abnormal | 98.96 | 9.91 | 409 | 245150 | 47772 | 63195691 |
Ill-defined disorder | 98.90 | 9.91 | 102 | 245457 | 81653 | 63161810 |
Blister | 97.45 | 9.91 | 224 | 245335 | 129590 | 63113873 |
Febrile neutropenia | 95.86 | 9.91 | 196 | 245363 | 118253 | 63125210 |
Arteriosclerosis coronary artery | 93.00 | 9.91 | 137 | 245422 | 8236 | 63235227 |
Amnesia | 91.65 | 9.91 | 442 | 245117 | 55143 | 63188320 |
Musculoskeletal stiffness | 91.46 | 9.91 | 385 | 245174 | 184233 | 63059230 |
Muscle spasms | 89.58 | 9.91 | 961 | 244598 | 155189 | 63088274 |
Haematemesis | 86.68 | 9.91 | 287 | 245272 | 30125 | 63213338 |
Hip arthroplasty | 86.33 | 9.91 | 38 | 245521 | 47608 | 63195855 |
Pregnancy | 85.22 | 9.91 | 19 | 245540 | 36817 | 63206646 |
Oedema peripheral | 85.17 | 9.91 | 1113 | 244446 | 188398 | 63055065 |
Fibromyalgia | 83.71 | 9.91 | 113 | 245446 | 80307 | 63163156 |
Bradycardia | 81.12 | 9.91 | 523 | 245036 | 72704 | 63170759 |
Necrotising myositis | 79.01 | 9.91 | 40 | 245519 | 517 | 63242946 |
Diabetes mellitus inadequate control | 77.48 | 9.91 | 177 | 245382 | 14949 | 63228514 |
Cerebral haemorrhage | 75.44 | 9.91 | 276 | 245283 | 30453 | 63213010 |
Renal impairment | 75.15 | 9.91 | 592 | 244967 | 87763 | 63155700 |
Confusional state | 74.67 | 9.91 | 1307 | 244252 | 235073 | 63008390 |
Angina pectoris | 74.56 | 9.91 | 271 | 245288 | 29807 | 63213656 |
Impaired healing | 73.72 | 9.91 | 181 | 245378 | 102361 | 63141102 |
Gait disturbance | 73 | 9.91 | 1053 | 244506 | 182125 | 63061338 |
Subarachnoid haemorrhage | 71.91 | 9.91 | 166 | 245393 | 14117 | 63229346 |
Haematochezia | 71.81 | 9.91 | 402 | 245157 | 53142 | 63190321 |
Nightmare | 71.49 | 9.91 | 199 | 245360 | 18995 | 63224468 |
Upper gastrointestinal haemorrhage | 70.76 | 9.91 | 196 | 245363 | 18656 | 63224807 |
Pyrexia | 69.82 | 9.91 | 1341 | 244218 | 469137 | 62774326 |
Knee arthroplasty | 66.27 | 9.91 | 67 | 245492 | 54139 | 63189324 |
Drug abuse | 65.72 | 9.91 | 112 | 245447 | 72406 | 63171057 |
Anaemia | 63.47 | 9.91 | 1534 | 244025 | 291896 | 62951567 |
Muscle atrophy | 62.69 | 9.91 | 104 | 245455 | 6929 | 63236534 |
Completed suicide | 62.52 | 9.91 | 320 | 245239 | 145353 | 63098110 |
Lip swelling | 62.46 | 9.91 | 262 | 245297 | 30801 | 63212662 |
Circulatory collapse | 61.60 | 9.91 | 206 | 245353 | 21732 | 63221731 |
Carotid artery occlusion | 61.31 | 9.91 | 83 | 245476 | 4611 | 63238852 |
Cardiospasm | 60.88 | 9.91 | 54 | 245505 | 1853 | 63241610 |
Chronic obstructive pulmonary disease | 60.64 | 9.91 | 433 | 245126 | 62253 | 63181210 |
Hyperglycaemia | 60.63 | 9.91 | 321 | 245238 | 41546 | 63201917 |
Palmoplantar keratoderma | 60.46 | 9.91 | 55 | 245504 | 1952 | 63241511 |
Swollen tongue | 59.01 | 9.91 | 279 | 245280 | 34521 | 63208942 |
Live birth | 57.74 | 9.91 | 14 | 245545 | 25616 | 63217847 |
Hypotension | 57.70 | 9.91 | 1421 | 244138 | 271183 | 62972280 |
Melaena | 57.11 | 9.91 | 251 | 245308 | 30114 | 63213349 |
Acute coronary syndrome | 56.94 | 9.91 | 123 | 245436 | 10003 | 63233460 |
Lethargy | 56.59 | 9.91 | 391 | 245168 | 55616 | 63187847 |
Pain in extremity | 56.25 | 9.91 | 1679 | 243880 | 329807 | 62913656 |
Cardiovascular disorder | 55.89 | 9.91 | 134 | 245425 | 11678 | 63231785 |
Palpitations | 54.74 | 9.91 | 672 | 244887 | 112098 | 63131365 |
Pruritus genital | 54.45 | 9.91 | 59 | 245500 | 2595 | 63240868 |
Sinus bradycardia | 54.33 | 9.91 | 151 | 245408 | 14400 | 63229063 |
Presyncope | 53.27 | 9.91 | 231 | 245328 | 27554 | 63215909 |
Malignant neoplasm progression | 52.92 | 9.91 | 153 | 245406 | 81968 | 63161495 |
Toxicity to various agents | 52.85 | 9.91 | 657 | 244902 | 246593 | 62996870 |
Arthralgia | 52.54 | 9.91 | 1742 | 243817 | 567968 | 62675495 |
Sleep terror | 52.24 | 9.91 | 58 | 245501 | 2622 | 63240841 |
Therapy non-responder | 52.21 | 9.91 | 137 | 245422 | 75764 | 63167699 |
Urosepsis | 52.06 | 9.91 | 174 | 245385 | 18350 | 63225113 |
Blood creatinine increased | 51.91 | 9.91 | 544 | 245015 | 87300 | 63156163 |
Haemorrhage intracranial | 51.84 | 9.91 | 141 | 245418 | 13278 | 63230185 |
Angina unstable | 51.67 | 9.91 | 96 | 245463 | 6999 | 63236464 |
Dyspnoea | 51.52 | 9.91 | 3085 | 242474 | 658228 | 62585235 |
Hypokalaemia | 50.57 | 9.91 | 619 | 244940 | 103185 | 63140278 |
Blood pressure inadequately controlled | 50.38 | 9.91 | 78 | 245481 | 4900 | 63238563 |
Coronary artery occlusion | 50.13 | 9.91 | 103 | 245456 | 8088 | 63235375 |
Chronic kidney disease | 49.51 | 9.91 | 323 | 245236 | 45075 | 63198388 |
Polymyositis | 49.37 | 9.91 | 47 | 245512 | 1769 | 63241694 |
Lower gastrointestinal haemorrhage | 49.22 | 9.91 | 100 | 245459 | 7790 | 63235673 |
Coronary artery stenosis | 48.95 | 9.91 | 75 | 245484 | 4669 | 63238794 |
Unresponsive to stimuli | 48.78 | 9.91 | 259 | 245300 | 33557 | 63209906 |
Weight increased | 48.51 | 9.91 | 713 | 244846 | 260079 | 62983384 |
Mitral valve incompetence | 48.10 | 9.91 | 176 | 245383 | 19418 | 63224045 |
Bone erosion | 47.92 | 9.91 | 6 | 245553 | 17711 | 63225752 |
Hypertensive crisis | 47.87 | 9.91 | 149 | 245410 | 15137 | 63228326 |
Carotid arteriosclerosis | 47.11 | 9.91 | 37 | 245522 | 1069 | 63242394 |
Foetal exposure during pregnancy | 47.05 | 9.91 | 33 | 245526 | 31929 | 63211534 |
Pancreatitis acute | 46.94 | 9.91 | 219 | 245340 | 26947 | 63216516 |
Muscle twitching | 46.89 | 9.91 | 175 | 245384 | 19493 | 63223970 |
Atrial tachycardia | 46.55 | 9.91 | 69 | 245490 | 4171 | 63239292 |
Premature delivery | 46.28 | 9.91 | 30 | 245529 | 30251 | 63213212 |
Disturbance in attention | 46.18 | 9.91 | 279 | 245280 | 37910 | 63205553 |
Cutaneous T-cell dyscrasia | 45.49 | 9.91 | 15 | 245544 | 55 | 63243408 |
Subdural haematoma | 44.25 | 9.91 | 139 | 245420 | 14189 | 63229274 |
Left ventricular hypertrophy | 43.94 | 9.91 | 76 | 245483 | 5239 | 63238224 |
Liver injury | 43.35 | 9.91 | 107 | 245452 | 60413 | 63183050 |
Ischaemic stroke | 42.99 | 9.91 | 160 | 245399 | 17797 | 63225666 |
Drug resistance | 42.00 | 9.91 | 18 | 245541 | 22915 | 63220548 |
Loss of consciousness | 41.97 | 9.91 | 666 | 244893 | 117455 | 63126008 |
Sedation complication | 41.82 | 9.91 | 3 | 245556 | 13819 | 63229644 |
Hyperhidrosis | 41.77 | 9.91 | 617 | 244942 | 107219 | 63136244 |
Femoral neck fracture | 41.75 | 9.91 | 98 | 245461 | 8425 | 63235038 |
Tendon rupture | 41.74 | 9.91 | 96 | 245463 | 8143 | 63235320 |
Sinus node dysfunction | 41.38 | 9.91 | 69 | 245490 | 4616 | 63238847 |
Muscle necrosis | 41.31 | 9.91 | 28 | 245531 | 640 | 63242823 |
Myelosuppression | 41.24 | 9.91 | 20 | 245539 | 23683 | 63219780 |
Caesarean section | 41.02 | 9.91 | 8 | 245551 | 17024 | 63226439 |
Prescribed overdose | 40.85 | 9.91 | 43 | 245516 | 34110 | 63209353 |
High density lipoprotein decreased | 40.65 | 9.91 | 46 | 245513 | 2124 | 63241339 |
Decorticate posture | 40.52 | 9.91 | 21 | 245538 | 286 | 63243177 |
Blood glucose decreased | 40.02 | 9.91 | 174 | 245385 | 20778 | 63222685 |
Peripheral swelling | 39.97 | 9.91 | 756 | 244803 | 265186 | 62978277 |
Pancreatitis | 39.69 | 9.91 | 325 | 245234 | 48730 | 63194733 |
Urinary tract infection | 38.66 | 9.91 | 1317 | 244242 | 263367 | 62980096 |
Tachyarrhythmia | 38.59 | 9.91 | 65 | 245494 | 4385 | 63239078 |
Immunisation | 38.52 | 9.91 | 34 | 245525 | 1159 | 63242304 |
Peripheral vascular disorder | 38.25 | 9.91 | 77 | 245482 | 5958 | 63237505 |
Myocardial depression | 38.20 | 9.91 | 24 | 245535 | 480 | 63242983 |
Collagen disorder | 37.71 | 9.91 | 18 | 245541 | 203 | 63243260 |
Myoglobin blood increased | 37.51 | 9.91 | 36 | 245523 | 1369 | 63242094 |
Ventricular tachycardia | 36.70 | 9.91 | 164 | 245395 | 19815 | 63223648 |
Labile hypertension | 36.48 | 9.91 | 23 | 245536 | 463 | 63243000 |
Head injury | 36.27 | 9.91 | 205 | 245354 | 27191 | 63216272 |
Blood loss anaemia | 36.20 | 9.91 | 96 | 245463 | 8905 | 63234558 |
Anosmia | 35.94 | 9.91 | 81 | 245478 | 6779 | 63236684 |
Illness | 35.71 | 9.91 | 86 | 245473 | 48973 | 63194490 |
Diabetic ketoacidosis | 35.20 | 9.91 | 165 | 245394 | 20340 | 63223123 |
Tension headache | 35.08 | 9.91 | 68 | 245491 | 5118 | 63238345 |
Migraine | 34.84 | 9.91 | 245 | 245314 | 103101 | 63140362 |
Haematuria | 34.61 | 9.91 | 212 | 245347 | 28945 | 63214518 |
Intermittent claudication | 34.48 | 9.91 | 39 | 245520 | 1800 | 63241663 |
Disease progression | 34.43 | 9.91 | 306 | 245253 | 122452 | 63121011 |
Chromaturia | 34.39 | 9.91 | 142 | 245417 | 16575 | 63226888 |
Ischaemic cardiomyopathy | 34.20 | 9.91 | 45 | 245514 | 2432 | 63241031 |
Hypothermia | 34.19 | 9.91 | 123 | 245436 | 13458 | 63230005 |
COVID-19 | 33.93 | 9.91 | 277 | 245282 | 112826 | 63130637 |
Femoral hernia incarcerated | 33.40 | 9.91 | 27 | 245532 | 814 | 63242649 |
Peripheral arterial occlusive disease | 33.34 | 9.91 | 59 | 245500 | 4142 | 63239321 |
Drug ineffective for unapproved indication | 33.32 | 9.91 | 50 | 245509 | 34013 | 63209450 |
Blindness | 33.23 | 9.91 | 169 | 245390 | 21530 | 63221933 |
Diverticulum | 33.13 | 9.91 | 112 | 245447 | 11879 | 63231584 |
Gouty tophus | 33.03 | 9.91 | 17 | 245542 | 228 | 63243235 |
Haematoma | 32.79 | 9.91 | 239 | 245320 | 34581 | 63208882 |
Injection site pain | 32.39 | 9.91 | 333 | 245226 | 129467 | 63113996 |
Aortic arteriosclerosis | 32.18 | 9.91 | 73 | 245486 | 6136 | 63237327 |
Arrhythmia | 32.11 | 9.91 | 255 | 245304 | 37885 | 63205578 |
Hemiparesis | 32.01 | 9.91 | 176 | 245383 | 23106 | 63220357 |
Coronary artery thrombosis | 31.96 | 9.91 | 30 | 245529 | 1109 | 63242354 |
Electrocardiogram QT prolonged | 31.63 | 9.91 | 361 | 245198 | 59169 | 63184294 |
Malaise | 31.63 | 9.91 | 1937 | 243622 | 414017 | 62829446 |
Torsade de pointes | 31.17 | 9.91 | 118 | 245441 | 13233 | 63230230 |
Hospitalisation | 30.52 | 9.91 | 198 | 245361 | 84883 | 63158580 |
Deep vein thrombosis postoperative | 30.39 | 9.91 | 4 | 245555 | 11365 | 63232098 |
Dysarthria | 29.86 | 9.91 | 274 | 245285 | 42437 | 63201026 |
Premature labour | 29.84 | 9.91 | 6 | 245553 | 12498 | 63230965 |
Muscle disorder | 29.84 | 9.91 | 62 | 245497 | 4907 | 63238556 |
Myoglobinuria | 29.80 | 9.91 | 17 | 245542 | 283 | 63243180 |
Postprandial hypoglycaemia | 29.72 | 9.91 | 11 | 245548 | 61 | 63243402 |
Haemodialysis | 29.68 | 9.91 | 89 | 245470 | 8858 | 63234605 |
Injection site reaction | 29.59 | 9.91 | 121 | 245438 | 58403 | 63185060 |
Swelling face | 29.39 | 9.91 | 375 | 245184 | 63100 | 63180363 |
Cytomegalovirus infection | 29.08 | 9.91 | 23 | 245536 | 20929 | 63222534 |
Disorientation | 29.07 | 9.91 | 256 | 245303 | 39196 | 63204267 |
Neutropenia | 28.96 | 9.91 | 489 | 245070 | 174516 | 63068947 |
Facial paresis | 28.89 | 9.91 | 50 | 245509 | 3448 | 63240015 |
Crystal nephropathy | 28.88 | 9.91 | 26 | 245533 | 910 | 63242553 |
Device difficult to use | 28.80 | 9.91 | 7 | 245552 | 12789 | 63230674 |
Arteriosclerosis | 28.68 | 9.91 | 95 | 245464 | 9971 | 63233492 |
Fatigue | 28.45 | 9.91 | 3005 | 242554 | 885023 | 62358440 |
Adverse drug reaction | 28.35 | 9.91 | 186 | 245373 | 79528 | 63163935 |
Colitis microscopic | 28.29 | 9.91 | 90 | 245469 | 9249 | 63234214 |
Pancreatitis necrotising | 28.25 | 9.91 | 34 | 245525 | 1678 | 63241785 |
Grip strength decreased | 27.87 | 9.91 | 27 | 245532 | 22260 | 63221203 |
Autoimmune hepatitis | 27.62 | 9.91 | 84 | 245475 | 8426 | 63235037 |
Glomerular filtration rate decreased | 27.51 | 9.91 | 114 | 245445 | 13327 | 63230136 |
Blood cholesterol increased | 27.43 | 9.91 | 232 | 245327 | 93800 | 63149663 |
Glycogen storage disease type V | 27.35 | 9.91 | 6 | 245553 | 0 | 63243463 |
Body temperature decreased | 27.33 | 9.91 | 23 | 245536 | 20296 | 63223167 |
Varicose vein | 27.32 | 9.91 | 60 | 245499 | 4935 | 63238528 |
Hallucination, visual | 27.28 | 9.91 | 147 | 245412 | 19151 | 63224312 |
Diplopia | 27.21 | 9.91 | 171 | 245388 | 23557 | 63219906 |
Cerebrospinal fluid retention | 27.10 | 9.91 | 11 | 245548 | 81 | 63243382 |
Inappropriate schedule of product administration | 27.06 | 9.91 | 264 | 245295 | 103701 | 63139762 |
Pancreatic steatosis | 27.06 | 9.91 | 26 | 245533 | 990 | 63242473 |
Hip fracture | 27.01 | 9.91 | 201 | 245358 | 29273 | 63214190 |
Nodular rash | 26.99 | 9.91 | 14 | 245545 | 191 | 63243272 |
Type 2 diabetes mellitus | 26.99 | 9.91 | 141 | 245418 | 63727 | 63179736 |
Breast cancer stage III | 26.95 | 9.91 | 4 | 245555 | 10382 | 63233081 |
Angioplasty | 26.92 | 9.91 | 30 | 245529 | 1362 | 63242101 |
Faeces discoloured | 26.85 | 9.91 | 142 | 245417 | 18367 | 63225096 |
Glycosylated haemoglobin increased | 26.84 | 9.91 | 107 | 245452 | 12291 | 63231172 |
Foetal death | 26.77 | 9.91 | 5 | 245554 | 10975 | 63232488 |
Abnormal loss of weight | 26.72 | 9.91 | 65 | 245494 | 5717 | 63237746 |
Quadriparesis | 26.69 | 9.91 | 36 | 245523 | 1993 | 63241470 |
Haemorrhagic stroke | 26.65 | 9.91 | 65 | 245494 | 5727 | 63237736 |
Visual impairment | 26.63 | 9.91 | 467 | 245092 | 83979 | 63159484 |
Facet joint syndrome | 26.63 | 9.91 | 7 | 245552 | 12131 | 63231332 |
Musculoskeletal toxicity | 26.50 | 9.91 | 10 | 245549 | 59 | 63243404 |
Wheezing | 26.49 | 9.91 | 239 | 245320 | 95356 | 63148107 |
Neutrophil count decreased | 26.45 | 9.91 | 120 | 245439 | 56286 | 63187177 |
Post viral fatigue syndrome | 26.33 | 9.91 | 16 | 245543 | 301 | 63243162 |
Cold sweat | 26.10 | 9.91 | 104 | 245455 | 11943 | 63231520 |
Blood urea increased | 25.96 | 9.91 | 183 | 245376 | 26196 | 63217267 |
Oesophagitis | 25.93 | 9.91 | 121 | 245438 | 14887 | 63228576 |
Liver function test increased | 25.93 | 9.91 | 55 | 245504 | 32756 | 63210707 |
Carotid artery stenosis | 25.93 | 9.91 | 60 | 245499 | 5110 | 63238353 |
Joint range of motion decreased | 25.93 | 9.91 | 54 | 245505 | 32374 | 63211089 |
Haemarthrosis | 25.87 | 9.91 | 45 | 245514 | 3116 | 63240347 |
Wound dehiscence | 25.81 | 9.91 | 58 | 245501 | 4845 | 63238618 |
Low density lipoprotein increased | 25.77 | 9.91 | 68 | 245491 | 6289 | 63237174 |
Ear pain | 25.75 | 9.91 | 64 | 245495 | 36054 | 63207409 |
Blood sodium decreased | 25.50 | 9.91 | 171 | 245388 | 24081 | 63219382 |
Myocardial ischaemia | 25.49 | 9.91 | 108 | 245451 | 12751 | 63230712 |
Myopathy toxic | 25.36 | 9.91 | 19 | 245540 | 511 | 63242952 |
Tremor | 25.20 | 9.91 | 680 | 244879 | 131559 | 63111904 |
Visual acuity reduced | 24.84 | 9.91 | 157 | 245402 | 21669 | 63221794 |
Cerebral infarction | 24.84 | 9.91 | 168 | 245391 | 23725 | 63219738 |
Oedema mouth | 24.69 | 9.91 | 38 | 245521 | 2375 | 63241088 |
Vascular stent stenosis | 24.64 | 9.91 | 19 | 245540 | 534 | 63242929 |
Lymphatic fistula | 24.58 | 9.91 | 22 | 245537 | 764 | 63242699 |
Blood pressure fluctuation | 24.54 | 9.91 | 94 | 245465 | 46223 | 63197240 |
Vision blurred | 24.39 | 9.91 | 495 | 245064 | 91429 | 63152034 |
Facial pain | 24.37 | 9.91 | 93 | 245466 | 10468 | 63232995 |
Hyperlipidaemia | 24.31 | 9.91 | 144 | 245415 | 19427 | 63224036 |
Asthma | 24.29 | 9.91 | 347 | 245212 | 127214 | 63116249 |
Adjustment disorder with depressed mood | 24.14 | 9.91 | 5 | 245554 | 10199 | 63233264 |
Urinary retention | 24.10 | 9.91 | 200 | 245359 | 30101 | 63213362 |
Diabetic hyperosmolar coma | 24.06 | 9.91 | 16 | 245543 | 354 | 63243109 |
Retinal artery thrombosis | 24.04 | 9.91 | 10 | 245549 | 79 | 63243384 |
Night sweats | 24.01 | 9.91 | 102 | 245457 | 48712 | 63194751 |
Memory impairment | 24.00 | 9.91 | 550 | 245009 | 103708 | 63139755 |
Hepatic cyst | 23.88 | 9.91 | 58 | 245501 | 5096 | 63238367 |
Electrocardiogram abnormal | 23.85 | 9.91 | 84 | 245475 | 9095 | 63234368 |
Extrasystoles | 23.84 | 9.91 | 58 | 245501 | 5102 | 63238361 |
Therapy partial responder | 23.66 | 9.91 | 6 | 245553 | 10652 | 63232811 |
Exercise tolerance decreased | 23.51 | 9.91 | 60 | 245499 | 5437 | 63238026 |
Parkinsonism | 23.33 | 9.91 | 91 | 245468 | 10348 | 63233115 |
Erythema dyschromicum perstans | 23.32 | 9.91 | 9 | 245550 | 57 | 63243406 |
Suicide attempt | 23.28 | 9.91 | 139 | 245420 | 60779 | 63182684 |
Bundle branch block left | 23.21 | 9.91 | 70 | 245489 | 6989 | 63236474 |
Balance disorder | 23.19 | 9.91 | 457 | 245102 | 83965 | 63159498 |
International normalised ratio abnormal | 23.18 | 9.91 | 44 | 245515 | 3260 | 63240203 |
Product used for unknown indication | 23.10 | 9.91 | 18 | 245541 | 514 | 63242949 |
Brucellosis | 23.06 | 9.91 | 9 | 245550 | 59 | 63243404 |
Ventricular extrasystoles | 23.04 | 9.91 | 98 | 245461 | 11589 | 63231874 |
Acetonaemia | 22.89 | 9.91 | 11 | 245548 | 126 | 63243337 |
Apolipoprotein A-I decreased | 22.80 | 9.91 | 7 | 245552 | 19 | 63243444 |
Speech disorder | 22.77 | 9.91 | 249 | 245310 | 40380 | 63203083 |
Electrolyte imbalance | 22.60 | 9.91 | 144 | 245415 | 19932 | 63223531 |
Ageusia | 22.50 | 9.91 | 109 | 245450 | 13619 | 63229844 |
Lichenoid keratosis | 22.49 | 9.91 | 31 | 245528 | 1752 | 63241711 |
Tricuspid valve incompetence | 22.48 | 9.91 | 114 | 245445 | 14507 | 63228956 |
Drug hypersensitivity | 22.34 | 9.91 | 978 | 244581 | 309709 | 62933754 |
Lung disorder | 22.27 | 9.91 | 145 | 245414 | 62116 | 63181347 |
Inflammation | 22.23 | 9.91 | 207 | 245352 | 82066 | 63161397 |
Transplant rejection | 22.21 | 9.91 | 7 | 245552 | 10773 | 63232690 |
Dyslipidaemia | 22.17 | 9.91 | 71 | 245488 | 7322 | 63236141 |
Poor venous access | 22.12 | 9.91 | 15 | 245544 | 14770 | 63228693 |
Disability | 22.05 | 9.91 | 23 | 245536 | 18324 | 63225139 |
Haemoglobin decreased | 21.74 | 9.91 | 726 | 244833 | 144759 | 63098704 |
Bursitis | 21.74 | 9.91 | 72 | 245487 | 36969 | 63206494 |
Incorrect route of product administration | 21.71 | 9.91 | 46 | 245513 | 27406 | 63216057 |
Tinnitus | 21.68 | 9.91 | 222 | 245337 | 35406 | 63208057 |
Atrioventricular block | 21.64 | 9.91 | 72 | 245487 | 7575 | 63235888 |
Sleep disorder due to a general medical condition | 21.64 | 9.91 | 10 | 245549 | 12178 | 63231285 |
Toxic shock syndrome | 21.40 | 9.91 | 21 | 245538 | 821 | 63242642 |
Alanine aminotransferase increased | 21.33 | 9.91 | 539 | 245020 | 103231 | 63140232 |
Device issue | 21.29 | 9.91 | 37 | 245522 | 23744 | 63219719 |
Autoimmune disorder | 21.25 | 9.91 | 21 | 245538 | 17156 | 63226307 |
Ankylosing spondylitis | 21.22 | 9.91 | 7 | 245552 | 10467 | 63232996 |
Neuropathy, ataxia, retinitis pigmentosa syndrome | 21.09 | 9.91 | 8 | 245551 | 48 | 63243415 |
Serotonin syndrome | 21.07 | 9.91 | 186 | 245373 | 28496 | 63214967 |
Seroma | 21.02 | 9.91 | 33 | 245526 | 2098 | 63241365 |
Loss of personal independence in daily activities | 20.95 | 9.91 | 258 | 245301 | 97032 | 63146431 |
Blood glucose fluctuation | 20.68 | 9.91 | 51 | 245508 | 4525 | 63238938 |
Hypovolaemia | 20.66 | 9.91 | 89 | 245470 | 10584 | 63232879 |
Therapeutic response decreased | 20.66 | 9.91 | 146 | 245413 | 61379 | 63182084 |
Diverticulum intestinal | 20.62 | 9.91 | 65 | 245494 | 6648 | 63236815 |
Hallucination | 20.57 | 9.91 | 312 | 245247 | 54505 | 63188958 |
Heavy menstrual bleeding | 20.56 | 9.91 | 23 | 245536 | 17750 | 63225713 |
Duodenal ulcer repair | 20.43 | 9.91 | 8 | 245551 | 53 | 63243410 |
Injection site bruising | 20.35 | 9.91 | 88 | 245471 | 41822 | 63201641 |
Mobility decreased | 20.21 | 9.91 | 338 | 245221 | 120821 | 63122642 |
Accidental exposure to product | 19.98 | 9.91 | 48 | 245511 | 27357 | 63216106 |
Mitochondrial myopathy | 19.97 | 9.91 | 9 | 245550 | 88 | 63243375 |
Feeling abnormal | 19.81 | 9.91 | 731 | 244828 | 147661 | 63095802 |
Aphasia | 19.78 | 9.91 | 205 | 245354 | 32795 | 63210668 |
Helicobacter gastritis | 19.76 | 9.91 | 28 | 245531 | 1624 | 63241839 |
Contraindicated product prescribed | 19.75 | 9.91 | 25 | 245534 | 1300 | 63242163 |
Premature baby | 19.74 | 9.91 | 31 | 245528 | 20704 | 63222759 |
Injection site erythema | 19.68 | 9.91 | 216 | 245343 | 82958 | 63160505 |
Blood triglycerides increased | 19.64 | 9.91 | 98 | 245461 | 12390 | 63231073 |
Mucosal inflammation | 19.60 | 9.91 | 104 | 245455 | 46824 | 63196639 |
Cerebellar ischaemia | 19.58 | 9.91 | 8 | 245551 | 60 | 63243403 |
Illness anxiety disorder | 19.57 | 9.91 | 10 | 245549 | 132 | 63243331 |
Maternal exposure before pregnancy | 19.56 | 9.91 | 3 | 245556 | 7600 | 63235863 |
Rectal haemorrhage | 19.55 | 9.91 | 282 | 245277 | 48748 | 63194715 |
Endocrine ophthalmopathy | 19.46 | 9.91 | 18 | 245541 | 653 | 63242810 |
Tenosynovitis | 19.33 | 9.91 | 15 | 245544 | 13780 | 63229683 |
Product dose omission issue | 19.32 | 9.91 | 726 | 244833 | 233587 | 63009876 |
Therapeutic response shortened | 19.25 | 9.91 | 11 | 245548 | 11877 | 63231586 |
General physical health deterioration | 19.22 | 9.91 | 958 | 244601 | 200444 | 63043019 |
Arterial stenosis | 19.20 | 9.91 | 17 | 245542 | 582 | 63242881 |
Faeces pale | 18.93 | 9.91 | 28 | 245531 | 1689 | 63241774 |
Hypomagnesaemia | 18.91 | 9.91 | 182 | 245377 | 28555 | 63214908 |
Conjunctival discolouration | 18.89 | 9.91 | 9 | 245550 | 101 | 63243362 |
Amaurosis fugax | 18.87 | 9.91 | 15 | 245544 | 441 | 63243022 |
Degenerative aortic valve disease | 18.74 | 9.91 | 10 | 245549 | 145 | 63243318 |
Listless | 18.74 | 9.91 | 37 | 245522 | 2823 | 63240640 |
Urticaria | 18.69 | 9.91 | 493 | 245066 | 165309 | 63078154 |
Blood potassium increased | 18.59 | 9.91 | 128 | 245431 | 18181 | 63225282 |
Renal injury | 18.49 | 9.91 | 79 | 245480 | 9360 | 63234103 |
Aortic valve stenosis | 18.47 | 9.91 | 40 | 245519 | 3259 | 63240204 |
Abnormal dreams | 18.33 | 9.91 | 85 | 245474 | 10431 | 63233032 |
Fear | 18.31 | 9.91 | 114 | 245445 | 15652 | 63227811 |
Cytokine release syndrome | 18.29 | 9.91 | 17 | 245542 | 14297 | 63229166 |
Low turnover osteopathy | 18.23 | 9.91 | 46 | 245513 | 4139 | 63239324 |
Dysphagia | 18.17 | 9.91 | 460 | 245099 | 88125 | 63155338 |
Rhinorrhoea | 18.14 | 9.91 | 164 | 245395 | 65413 | 63178050 |
Wound infection pseudomonas | 18.14 | 9.91 | 24 | 245535 | 1304 | 63242159 |
Diabetes mellitus | 18.08 | 9.91 | 310 | 245249 | 55500 | 63187963 |
Fear of injection | 18.04 | 9.91 | 3 | 245556 | 7161 | 63236302 |
Systemic infection | 18.03 | 9.91 | 49 | 245510 | 4611 | 63238852 |
Cardiac failure | 18.02 | 9.91 | 462 | 245097 | 88680 | 63154783 |
Carotid bruit | 17.98 | 9.91 | 18 | 245541 | 721 | 63242742 |
Intentional overdose | 17.77 | 9.91 | 192 | 245367 | 73960 | 63169503 |
Gastric ulcer | 17.72 | 9.91 | 156 | 245403 | 23881 | 63219582 |
Apraxia | 17.69 | 9.91 | 28 | 245531 | 1793 | 63241670 |
Wound infection | 17.67 | 9.91 | 35 | 245524 | 21375 | 63222088 |
Anal incontinence | 17.58 | 9.91 | 101 | 245458 | 13475 | 63229988 |
Arthritis | 17.55 | 9.91 | 329 | 245230 | 115592 | 63127871 |
Arterial haemorrhage | 17.51 | 9.91 | 27 | 245532 | 1690 | 63241773 |
Disease recurrence | 17.49 | 9.91 | 53 | 245506 | 27977 | 63215486 |
Pancreatic carcinoma | 17.46 | 9.91 | 67 | 245492 | 7561 | 63235902 |
Amyotrophic lateral sclerosis | 17.42 | 9.91 | 22 | 245537 | 1141 | 63242322 |
Pain of skin | 17.39 | 9.91 | 90 | 245469 | 11544 | 63231919 |
Femur fracture | 17.39 | 9.91 | 242 | 245317 | 41514 | 63201949 |
Neoplasm progression | 17.38 | 9.91 | 77 | 245482 | 36351 | 63207112 |
Sedation | 17.35 | 9.91 | 84 | 245475 | 38725 | 63204738 |
Asphyxia | 17.31 | 9.91 | 58 | 245501 | 6123 | 63237340 |
Poisoning deliberate | 17.30 | 9.91 | 11 | 245548 | 11207 | 63232256 |
Vulvovaginal burning sensation | 17.23 | 9.91 | 30 | 245529 | 2079 | 63241384 |
Hypoglycaemic unconsciousness | 17.23 | 9.91 | 18 | 245541 | 759 | 63242704 |
X-ray abnormal | 17.19 | 9.91 | 5 | 245554 | 8105 | 63235358 |
Ventricular hypokinesia | 17.15 | 9.91 | 48 | 245511 | 4596 | 63238867 |
Labelled drug-food interaction medication error | 17.14 | 9.91 | 10 | 245549 | 174 | 63243289 |
Gastritis | 17.10 | 9.91 | 220 | 245339 | 37083 | 63206380 |
International normalised ratio decreased | 17.09 | 9.91 | 47 | 245512 | 4454 | 63239009 |
Ketoacidosis | 16.91 | 9.91 | 46 | 245513 | 4332 | 63239131 |
Hand-eye coordination impaired | 16.88 | 9.91 | 6 | 245553 | 29 | 63243434 |
Spontaneous haematoma | 16.85 | 9.91 | 19 | 245540 | 874 | 63242589 |
Myoclonus | 16.75 | 9.91 | 112 | 245447 | 15756 | 63227707 |
Jaundice | 16.73 | 9.91 | 180 | 245379 | 29071 | 63214392 |
Ubiquinone decreased | 16.72 | 9.91 | 5 | 245554 | 12 | 63243451 |
Sodium retention | 16.72 | 9.91 | 9 | 245550 | 133 | 63243330 |
Groin pain | 16.71 | 9.91 | 81 | 245478 | 10122 | 63233341 |
Anuria | 16.67 | 9.91 | 94 | 245465 | 12457 | 63231006 |
Coronary arterial stent insertion | 16.64 | 9.91 | 35 | 245524 | 2794 | 63240669 |
Loose tooth | 16.60 | 9.91 | 39 | 245520 | 3355 | 63240108 |
Pharyngitis | 16.56 | 9.91 | 33 | 245526 | 20110 | 63223353 |
Pancreatitis relapsing | 16.56 | 9.91 | 19 | 245540 | 891 | 63242572 |
Febrile bone marrow aplasia | 16.50 | 9.91 | 4 | 245555 | 7321 | 63236142 |
Linear IgA disease | 16.49 | 9.91 | 24 | 245535 | 1427 | 63242036 |
Tachycardia | 16.49 | 9.91 | 585 | 244974 | 117571 | 63125892 |
Electrocardiogram PR prolongation | 16.46 | 9.91 | 17 | 245542 | 707 | 63242756 |
Retinal coloboma | 16.40 | 9.91 | 6 | 245553 | 32 | 63243431 |
Erythromelalgia | 16.31 | 9.91 | 9 | 245550 | 140 | 63243323 |
Autoimmune myositis | 16.31 | 9.91 | 9 | 245550 | 140 | 63243323 |
Sinus arrest | 16.28 | 9.91 | 28 | 245531 | 1921 | 63241542 |
Haematotoxicity | 16.17 | 9.91 | 8 | 245551 | 9368 | 63234095 |
Sprue-like enteropathy | 16.09 | 9.91 | 17 | 245542 | 726 | 63242737 |
Pulmonary oedema | 16.08 | 9.91 | 300 | 245259 | 54573 | 63188890 |
Metastases to bone | 15.98 | 9.91 | 36 | 245523 | 20983 | 63222480 |
Peripheral venous disease | 15.84 | 9.91 | 22 | 245537 | 15455 | 63228008 |
Intraventricular haemorrhage | 15.83 | 9.91 | 29 | 245530 | 2091 | 63241372 |
Lymph node palpable | 15.83 | 9.91 | 8 | 245551 | 103 | 63243360 |
Transient global amnesia | 15.82 | 9.91 | 16 | 245543 | 649 | 63242814 |
Gait inability | 15.68 | 9.91 | 290 | 245269 | 52669 | 63190794 |
Brain contusion | 15.64 | 9.91 | 15 | 245544 | 570 | 63242893 |
Cognitive disorder | 15.62 | 9.91 | 303 | 245256 | 55512 | 63187951 |
Cerebral amyloid angiopathy | 15.61 | 9.91 | 9 | 245550 | 153 | 63243310 |
Subclavian vein thrombosis | 15.59 | 9.91 | 27 | 245532 | 1863 | 63241600 |
White blood cell count decreased | 15.57 | 9.91 | 414 | 245145 | 138690 | 63104773 |
Cerebellar infarction | 15.56 | 9.91 | 28 | 245531 | 1991 | 63241472 |
Hypophagia | 15.47 | 9.91 | 187 | 245372 | 31072 | 63212391 |
Vasculitis | 15.46 | 9.91 | 122 | 245437 | 18087 | 63225376 |
Language disorder | 15.45 | 9.91 | 29 | 245530 | 2131 | 63241332 |
Pathogen resistance | 15.42 | 9.91 | 3 | 245556 | 6395 | 63237068 |
Cerebral ischaemia | 15.32 | 9.91 | 59 | 245500 | 6669 | 63236794 |
Lacunar infarction | 15.29 | 9.91 | 37 | 245522 | 3243 | 63240220 |
Multiple injuries | 15.24 | 9.91 | 26 | 245533 | 1772 | 63241691 |
Iris coloboma | 15.16 | 9.91 | 6 | 245553 | 41 | 63243422 |
Muscle strength abnormal | 15.14 | 9.91 | 7 | 245552 | 73 | 63243390 |
Cerebral artery occlusion | 15.14 | 9.91 | 18 | 245541 | 877 | 63242586 |
Blood creatine phosphokinase MB increased | 15.13 | 9.91 | 21 | 245538 | 1195 | 63242268 |
Body height decreased | 15.09 | 9.91 | 78 | 245481 | 10000 | 63233463 |
Leukocyturia | 15.08 | 9.91 | 23 | 245536 | 1426 | 63242037 |
Parakeratosis | 15.07 | 9.91 | 11 | 245548 | 284 | 63243179 |
Device dislocation | 15.06 | 9.91 | 50 | 245509 | 25655 | 63217808 |
Tumour lysis syndrome | 15.02 | 9.91 | 8 | 245551 | 8982 | 63234481 |
Chronic sinusitis | 15 | 9.91 | 93 | 245466 | 12750 | 63230713 |
Blood urine | 14.98 | 9.91 | 13 | 245546 | 433 | 63243030 |
Cardiac disorder | 14.95 | 9.91 | 278 | 245281 | 50538 | 63192925 |
Brain stem infarction | 14.90 | 9.91 | 17 | 245542 | 792 | 63242671 |
Osteonecrosis of external auditory canal | 14.81 | 9.91 | 8 | 245551 | 119 | 63243344 |
Diabetic neuropathy | 14.66 | 9.91 | 41 | 245518 | 3923 | 63239540 |
Fracture blisters | 14.66 | 9.91 | 7 | 245552 | 79 | 63243384 |
Movement disorder | 14.66 | 9.91 | 138 | 245421 | 21523 | 63221940 |
Supraventricular extrasystoles | 14.62 | 9.91 | 45 | 245514 | 4544 | 63238919 |
Cardiogenic shock | 14.61 | 9.91 | 119 | 245440 | 17813 | 63225650 |
Acne | 14.56 | 9.91 | 44 | 245515 | 23249 | 63220214 |
Blood creatine phosphokinase abnormal | 14.55 | 9.91 | 10 | 245549 | 234 | 63243229 |
Bone marrow failure | 14.53 | 9.91 | 61 | 245498 | 29229 | 63214234 |
Mitral valve sclerosis | 14.52 | 9.91 | 8 | 245551 | 124 | 63243339 |
Temperature regulation disorder | 14.52 | 9.91 | 3 | 245556 | 6129 | 63237334 |
Diverticular perforation | 14.47 | 9.91 | 38 | 245521 | 3504 | 63239959 |
Ischaemia | 14.47 | 9.91 | 46 | 245513 | 4726 | 63238737 |
Femoral artery embolism | 14.46 | 9.91 | 6 | 245553 | 47 | 63243416 |
Adverse reaction | 14.41 | 9.91 | 11 | 245548 | 10192 | 63233271 |
Wrist fracture | 14.40 | 9.91 | 96 | 245463 | 13491 | 63229972 |
Genital swelling | 14.30 | 9.91 | 8 | 245551 | 128 | 63243335 |
Breast cancer stage II | 14.26 | 9.91 | 8 | 245551 | 8728 | 63234735 |
Dysgeusia | 14.25 | 9.91 | 257 | 245302 | 46453 | 63197010 |
Adverse event | 14.23 | 9.91 | 180 | 245379 | 67379 | 63176084 |
Dermatitis exfoliative | 14.22 | 9.91 | 50 | 245509 | 5409 | 63238054 |
Ear infection | 14.18 | 9.91 | 88 | 245471 | 38125 | 63205338 |
Mitral valve stenosis | 14.16 | 9.91 | 20 | 245539 | 1157 | 63242306 |
Nasal ulcer | 14.13 | 9.91 | 29 | 245530 | 2275 | 63241188 |
Bundle branch block right | 14.09 | 9.91 | 47 | 245512 | 4951 | 63238512 |
Drug dependence | 14.09 | 9.91 | 48 | 245511 | 24435 | 63219028 |
Product substitution issue | 14.04 | 9.91 | 108 | 245451 | 15888 | 63227575 |
Low birth weight baby | 14.04 | 9.91 | 5 | 245554 | 7124 | 63236339 |
Poliomyelitis | 13.94 | 9.91 | 6 | 245553 | 52 | 63243411 |
Urinary incontinence | 13.92 | 9.91 | 187 | 245372 | 31827 | 63211636 |
Lip dry | 13.91 | 9.91 | 24 | 245535 | 15446 | 63228017 |
Product dose omission in error | 13.90 | 9.91 | 6 | 245553 | 7606 | 63235857 |
Left ventricular failure | 13.89 | 9.91 | 51 | 245508 | 5636 | 63237827 |
Motor neurone disease | 13.88 | 9.91 | 8 | 245551 | 136 | 63243327 |
Self esteem decreased | 13.87 | 9.91 | 15 | 245544 | 658 | 63242805 |
Rash papular | 13.78 | 9.91 | 106 | 245453 | 15596 | 63227867 |
Bladder trabeculation | 13.75 | 9.91 | 6 | 245553 | 54 | 63243409 |
Foetal growth restriction | 13.72 | 9.91 | 6 | 245553 | 7547 | 63235916 |
Pneumocystis jirovecii pneumonia | 13.66 | 9.91 | 28 | 245531 | 16886 | 63226577 |
Orbital swelling | 13.65 | 9.91 | 6 | 245553 | 55 | 63243408 |
Body temperature increased | 13.62 | 9.91 | 86 | 245473 | 37106 | 63206357 |
Amenorrhoea | 13.61 | 9.91 | 11 | 245548 | 9903 | 63233560 |
Injection site swelling | 13.59 | 9.91 | 118 | 245441 | 47454 | 63196009 |
Coronary artery bypass | 13.58 | 9.91 | 29 | 245530 | 2340 | 63241123 |
Ataxia | 13.57 | 9.91 | 103 | 245456 | 15092 | 63228371 |
Infusion site pain | 13.56 | 9.91 | 28 | 245531 | 16841 | 63226622 |
Diabetic metabolic decompensation | 13.55 | 9.91 | 24 | 245535 | 1686 | 63241777 |
Uterine perforation | 13.51 | 9.91 | 5 | 245554 | 6958 | 63236505 |
Cerebellar ataxia | 13.41 | 9.91 | 17 | 245542 | 885 | 63242578 |
Influenza | 13.40 | 9.91 | 319 | 245240 | 108403 | 63135060 |
Rhinalgia | 13.39 | 9.91 | 23 | 245536 | 1576 | 63241887 |
C-reactive protein increased | 13.36 | 9.91 | 272 | 245287 | 94435 | 63149028 |
Inappropriate antidiuretic hormone secretion | 13.35 | 9.91 | 104 | 245455 | 15358 | 63228105 |
Oedema | 13.29 | 9.91 | 282 | 245277 | 97340 | 63146123 |
Device use error | 13.27 | 9.91 | 3 | 245556 | 5758 | 63237705 |
Coma scale abnormal | 13.25 | 9.91 | 47 | 245512 | 5106 | 63238357 |
Aortic valve incompetence | 13.22 | 9.91 | 52 | 245507 | 5936 | 63237527 |
Vulvar basal cell carcinoma | 13.18 | 9.91 | 5 | 245554 | 30 | 63243433 |
Vertigo | 13.18 | 9.91 | 314 | 245245 | 59573 | 63183890 |
Diarrhoea | 13.12 | 9.91 | 3039 | 242520 | 712327 | 62531136 |
Fracture displacement | 13.10 | 9.91 | 20 | 245539 | 1241 | 63242222 |
Biopsy muscle abnormal | 13.04 | 9.91 | 5 | 245554 | 31 | 63243432 |
Muscle spasticity | 13.04 | 9.91 | 42 | 245517 | 21752 | 63221711 |
Epistaxis | 13.01 | 9.91 | 371 | 245188 | 72354 | 63171109 |
Joint destruction | 12.99 | 9.91 | 4 | 245555 | 6248 | 63237215 |
Lower limb fracture | 12.93 | 9.91 | 49 | 245510 | 24172 | 63219291 |
Antineutrophil cytoplasmic antibody positive | 12.92 | 9.91 | 14 | 245545 | 616 | 63242847 |
Blood pressure systolic increased | 12.91 | 9.91 | 119 | 245440 | 47278 | 63196185 |
Stress fracture | 12.89 | 9.91 | 63 | 245496 | 7900 | 63235563 |
Red cell distribution width increased | 12.87 | 9.91 | 13 | 245546 | 10511 | 63232952 |
Nasal dryness | 12.84 | 9.91 | 43 | 245516 | 4538 | 63238925 |
Eructation | 12.83 | 9.91 | 65 | 245494 | 8268 | 63235195 |
Vomiting | 12.80 | 9.91 | 2403 | 243156 | 557214 | 62686249 |
Macroangiopathy | 12.80 | 9.91 | 7 | 245552 | 107 | 63243356 |
Periorbital inflammation | 12.78 | 9.91 | 6 | 245553 | 65 | 63243398 |
Respiratory tract haemorrhage | 12.77 | 9.91 | 12 | 245547 | 444 | 63243019 |
Hyperthermia | 12.77 | 9.91 | 10 | 245549 | 9146 | 63234317 |
Blood pressure systolic abnormal | 12.75 | 9.91 | 20 | 245539 | 13366 | 63230097 |
Orthopnoea | 12.73 | 9.91 | 53 | 245506 | 6208 | 63237255 |
Exposure to toxic agent | 12.69 | 9.91 | 3 | 245556 | 5584 | 63237879 |
Gingival hypertrophy | 12.66 | 9.91 | 23 | 245536 | 1648 | 63241815 |
Injury | 12.65 | 9.91 | 203 | 245356 | 73044 | 63170419 |
Respiratory disorder | 12.51 | 9.91 | 94 | 245465 | 38988 | 63204475 |
Deep vein thrombosis | 12.47 | 9.91 | 418 | 245141 | 83382 | 63160081 |
Tuberculosis | 12.44 | 9.91 | 15 | 245544 | 11196 | 63232267 |
Haemorrhagic erosive gastritis | 12.40 | 9.91 | 12 | 245547 | 461 | 63243002 |
Metabolic acidosis | 12.38 | 9.91 | 244 | 245315 | 44825 | 63198638 |
Ovarian cyst | 12.37 | 9.91 | 27 | 245532 | 15918 | 63227545 |
Pulmonary toxicity | 12.36 | 9.91 | 11 | 245548 | 9444 | 63234019 |
Potentiating drug interaction | 12.31 | 9.91 | 41 | 245518 | 4315 | 63239148 |
Cardiomegaly | 12.31 | 9.91 | 113 | 245446 | 17501 | 63225962 |
Nasal polyps | 12.30 | 9.91 | 4 | 245555 | 6035 | 63237428 |
Eyelid bleeding | 12.30 | 9.91 | 5 | 245554 | 37 | 63243426 |
Facial nerve disorder | 12.29 | 9.91 | 13 | 245546 | 556 | 63242907 |
Nervousness | 12.28 | 9.91 | 178 | 245381 | 30801 | 63212662 |
Long QT syndrome | 12.21 | 9.91 | 34 | 245525 | 3245 | 63240218 |
Laryngitis | 12.14 | 9.91 | 30 | 245529 | 16937 | 63226526 |
Immunodeficiency | 12.14 | 9.91 | 39 | 245520 | 20215 | 63223248 |
Exfoliative rash | 12.10 | 9.91 | 31 | 245528 | 2816 | 63240647 |
Menstruation irregular | 12.05 | 9.91 | 6 | 245553 | 6998 | 63236465 |
Nodal rhythm | 11.97 | 9.91 | 23 | 245536 | 1720 | 63241743 |
Hypoglycaemic coma | 11.96 | 9.91 | 29 | 245530 | 2546 | 63240917 |
Blood alkaline phosphatase increased | 11.93 | 9.91 | 233 | 245326 | 42734 | 63200729 |
Breath sounds abnormal | 11.91 | 9.91 | 78 | 245481 | 10895 | 63232568 |
Radius fracture | 11.91 | 9.91 | 36 | 245523 | 3599 | 63239864 |
Dermatitis atopic | 11.90 | 9.91 | 12 | 245547 | 9712 | 63233751 |
Death | 11.88 | 9.91 | 1267 | 244292 | 373114 | 62870349 |
Obsessive thoughts | 11.88 | 9.91 | 13 | 245546 | 578 | 63242885 |
Muscle rupture | 11.87 | 9.91 | 28 | 245531 | 2415 | 63241048 |
Myoglobin urine | 11.86 | 9.91 | 4 | 245555 | 16 | 63243447 |
Normetanephrine urine increased | 11.86 | 9.91 | 4 | 245555 | 16 | 63243447 |
Spasmodic dysphonia | 11.82 | 9.91 | 6 | 245553 | 78 | 63243385 |
Orthostatic hypotension | 11.76 | 9.91 | 201 | 245358 | 35959 | 63207504 |
Tendon sheath incision | 11.75 | 9.91 | 6 | 245553 | 79 | 63243384 |
Anti-neutrophil cytoplasmic antibody positive vasculitis | 11.74 | 9.91 | 31 | 245528 | 2868 | 63240595 |
Spontaneous haemorrhage | 11.74 | 9.91 | 13 | 245546 | 586 | 63242877 |
Pancreatic carcinoma metastatic | 11.73 | 9.91 | 26 | 245533 | 2152 | 63241311 |
Breast cancer stage I | 11.70 | 9.91 | 6 | 245553 | 6883 | 63236580 |
Hypoaesthesia | 11.69 | 9.91 | 532 | 245027 | 167861 | 63075602 |
Retinal haemorrhage | 11.67 | 9.91 | 44 | 245515 | 4925 | 63238538 |
Respiratory tract congestion | 11.65 | 9.91 | 33 | 245526 | 17799 | 63225664 |
Peripheral artery stenosis | 11.58 | 9.91 | 13 | 245546 | 595 | 63242868 |
Genital haemorrhage | 11.57 | 9.91 | 7 | 245552 | 7325 | 63236138 |
Abscess jaw | 11.53 | 9.91 | 20 | 245539 | 1382 | 63242081 |
Peroneal nerve palsy | 11.51 | 9.91 | 43 | 245516 | 4792 | 63238671 |
Hiatus hernia | 11.49 | 9.91 | 131 | 245428 | 21463 | 63222000 |
Weight decreased | 11.37 | 9.91 | 1230 | 244329 | 275568 | 62967895 |
Breast atrophy | 11.37 | 9.91 | 6 | 245553 | 85 | 63243378 |
Enterococcal sepsis | 11.36 | 9.91 | 20 | 245539 | 1398 | 63242065 |
Peripheral embolism | 11.34 | 9.91 | 19 | 245540 | 1276 | 63242187 |
Ocular myasthenia | 11.32 | 9.91 | 7 | 245552 | 136 | 63243327 |
Skin pressure mark | 11.31 | 9.91 | 4 | 245555 | 19 | 63243444 |
Perseveration | 11.28 | 9.91 | 9 | 245550 | 266 | 63243197 |
Oxalosis | 11.27 | 9.91 | 5 | 245554 | 47 | 63243416 |
Osteoporosis | 11.26 | 9.91 | 155 | 245404 | 57183 | 63186280 |
Paresis | 11.22 | 9.91 | 28 | 245531 | 2502 | 63240961 |
Mouth swelling | 11.15 | 9.91 | 42 | 245517 | 4698 | 63238765 |
Pharyngeal oedema | 11.15 | 9.91 | 91 | 245468 | 13630 | 63229833 |
Gastric ulcer haemorrhage | 11.14 | 9.91 | 43 | 245516 | 4865 | 63238598 |
Injection site pruritus | 11.14 | 9.91 | 116 | 245443 | 45000 | 63198463 |
Pemphigoid | 11.11 | 9.91 | 57 | 245502 | 7287 | 63236176 |
Cardiac flutter | 11.09 | 9.91 | 38 | 245521 | 4058 | 63239405 |
Meibomianitis | 11.09 | 9.91 | 5 | 245554 | 49 | 63243414 |
Adrenal insufficiency | 11.09 | 9.91 | 34 | 245525 | 17881 | 63225582 |
Eyelid disorder | 11.02 | 9.91 | 23 | 245536 | 1826 | 63241637 |
Coronavirus test positive | 11.01 | 9.91 | 14 | 245545 | 731 | 63242732 |
Polymyalgia rheumatica | 11.00 | 9.91 | 36 | 245523 | 3755 | 63239708 |
Tessellated fundus | 11.00 | 9.91 | 5 | 245554 | 50 | 63243413 |
Degenerative mitral valve disease | 10.99 | 9.91 | 4 | 245555 | 21 | 63243442 |
Fracture | 10.96 | 9.91 | 120 | 245439 | 19464 | 63223999 |
Colitis ischaemic | 10.96 | 9.91 | 75 | 245484 | 10633 | 63232830 |
Eye swelling | 10.94 | 9.91 | 141 | 245418 | 23777 | 63219686 |
Cushingoid | 10.94 | 9.91 | 10 | 245549 | 8475 | 63234988 |
Aspartate aminotransferase increased | 10.92 | 9.91 | 440 | 245119 | 89837 | 63153626 |
Cerebral ventricular rupture | 10.91 | 9.91 | 8 | 245551 | 208 | 63243255 |
Coombs negative haemolytic anaemia | 10.91 | 9.91 | 8 | 245551 | 208 | 63243255 |
Ophthalmoplegia | 10.90 | 9.91 | 20 | 245539 | 1444 | 63242019 |
Food allergy | 10.89 | 9.91 | 17 | 245542 | 11384 | 63232079 |
Pulmonary hypertension | 10.89 | 9.91 | 203 | 245356 | 36920 | 63206543 |
Cerebrovascular disorder | 10.85 | 9.91 | 29 | 245530 | 2703 | 63240760 |
Intestinal angioedema | 10.79 | 9.91 | 13 | 245546 | 642 | 63242821 |
Occult blood positive | 10.78 | 9.91 | 35 | 245524 | 3635 | 63239828 |
Portal fibrosis | 10.78 | 9.91 | 9 | 245550 | 284 | 63243179 |
Hypernatraemia | 10.78 | 9.91 | 58 | 245501 | 7551 | 63235912 |
Large intestine polyp | 10.77 | 9.91 | 61 | 245498 | 8096 | 63235367 |
Electrocardiogram T wave abnormal | 10.77 | 9.91 | 27 | 245532 | 2420 | 63241043 |
Nausea | 10.74 | 9.91 | 3573 | 241986 | 850898 | 62392565 |
Hypertensive heart disease | 10.73 | 9.91 | 27 | 245532 | 2425 | 63241038 |
Androgenetic alopecia | 10.72 | 9.91 | 7 | 245552 | 150 | 63243313 |
Reversible ischaemic neurological deficit | 10.69 | 9.91 | 4 | 245555 | 23 | 63243440 |
Bacteraemia | 10.68 | 9.91 | 33 | 245526 | 17315 | 63226148 |
Electrocardiogram T wave peaked | 10.68 | 9.91 | 8 | 245551 | 215 | 63243248 |
Dialysis | 10.65 | 9.91 | 73 | 245486 | 10354 | 63233109 |
Forced expiratory volume decreased | 10.64 | 9.91 | 3 | 245556 | 4965 | 63238498 |
Oxygen saturation decreased | 10.62 | 9.91 | 261 | 245298 | 88324 | 63155139 |
Drug level decreased | 10.61 | 9.91 | 9 | 245550 | 7910 | 63235553 |
Aortic stenosis | 10.61 | 9.91 | 43 | 245516 | 4977 | 63238486 |
Monoparesis | 10.60 | 9.91 | 21 | 245538 | 1606 | 63241857 |
Cerebral arteriosclerosis | 10.57 | 9.91 | 9 | 245550 | 292 | 63243171 |
Medication error | 10.57 | 9.91 | 271 | 245288 | 52013 | 63191450 |
Peak expiratory flow rate abnormal | 10.56 | 9.91 | 6 | 245553 | 99 | 63243364 |
Sickle cell anaemia with crisis | 10.54 | 9.91 | 5 | 245554 | 5998 | 63237465 |
Microphthalmos | 10.52 | 9.91 | 7 | 245552 | 155 | 63243308 |
Pancreatitis chronic | 10.51 | 9.91 | 27 | 245532 | 2457 | 63241006 |
Peripheral ischaemia | 10.48 | 9.91 | 42 | 245517 | 4836 | 63238627 |
Gingivitis | 10.46 | 9.91 | 62 | 245497 | 8367 | 63235096 |
Hepatitis toxic | 10.45 | 9.91 | 32 | 245527 | 3221 | 63240242 |
Bronchiectasis | 10.45 | 9.91 | 30 | 245529 | 16112 | 63227351 |
Therapy interrupted | 10.42 | 9.91 | 78 | 245481 | 32377 | 63211086 |
Blood glucose abnormal | 10.41 | 9.91 | 59 | 245500 | 7833 | 63235630 |
Bladder cyst | 10.40 | 9.91 | 3 | 245556 | 6 | 63243457 |
Arcus lipoides | 10.40 | 9.91 | 3 | 245556 | 6 | 63243457 |
Haemorrhagic fever | 10.40 | 9.91 | 3 | 245556 | 6 | 63243457 |
Renal adenoma | 10.40 | 9.91 | 3 | 245556 | 6 | 63243457 |
Wrong patient received product | 10.40 | 9.91 | 25 | 245534 | 2182 | 63241281 |
Reflexes abnormal | 10.39 | 9.91 | 13 | 245546 | 668 | 63242795 |
Ejection fraction decreased | 10.36 | 9.91 | 132 | 245427 | 22200 | 63221263 |
Gastric cyst | 10.36 | 9.91 | 6 | 245553 | 103 | 63243360 |
Skin candida | 10.35 | 9.91 | 21 | 245538 | 1634 | 63241829 |
Drug therapeutic incompatibility | 10.35 | 9.91 | 5 | 245554 | 58 | 63243405 |
Transplant dysfunction | 10.33 | 9.91 | 3 | 245556 | 4869 | 63238594 |
Chronic pigmented purpura | 10.33 | 9.91 | 7 | 245552 | 160 | 63243303 |
Pulmonary embolism | 10.30 | 9.91 | 551 | 245008 | 116133 | 63127330 |
Nodule | 10.30 | 9.91 | 44 | 245515 | 20982 | 63222481 |
Mesenteric arterial occlusion | 10.29 | 9.91 | 7 | 245552 | 161 | 63243302 |
Low density lipoprotein abnormal | 10.28 | 9.91 | 8 | 245551 | 228 | 63243235 |
Cardiac failure chronic | 10.27 | 9.91 | 39 | 245520 | 4379 | 63239084 |
Oral herpes | 10.22 | 9.91 | 59 | 245500 | 26015 | 63217448 |
Blood pressure diastolic abnormal | 10.19 | 9.91 | 26 | 245533 | 14516 | 63228947 |
Bronchopulmonary aspergillosis | 10.18 | 9.91 | 11 | 245548 | 8624 | 63234839 |
Sweat gland tumour | 10.15 | 9.91 | 6 | 245553 | 107 | 63243356 |
Hypersensitivity vasculitis | 10.15 | 9.91 | 37 | 245522 | 4075 | 63239388 |
Gastrointestinal toxicity | 10.12 | 9.91 | 9 | 245550 | 7732 | 63235731 |
Muscle contractions involuntary | 10.12 | 9.91 | 26 | 245533 | 2366 | 63241097 |
Auricular swelling | 10.06 | 9.91 | 5 | 245554 | 62 | 63243401 |
Benign neoplasm of bladder | 10.03 | 9.91 | 4 | 245555 | 28 | 63243435 |
Pseudomonas bronchitis | 10.03 | 9.91 | 4 | 245555 | 28 | 63243435 |
Skin laceration | 10.02 | 9.91 | 133 | 245426 | 22575 | 63220888 |
Intestinal ischaemia | 9.96 | 9.91 | 56 | 245503 | 7412 | 63236051 |
Product commingling | 9.96 | 9.91 | 7 | 245552 | 170 | 63243293 |
Cardiac failure acute | 9.92 | 9.91 | 67 | 245492 | 9456 | 63234007 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Rhabdomyolysis | 2696.85 | 11.25 | 2836 | 242940 | 65327 | 34645828 |
Myalgia | 1224.13 | 11.25 | 2152 | 243624 | 81958 | 34629197 |
Blood creatine phosphokinase increased | 731.28 | 11.25 | 1208 | 244568 | 43649 | 34667506 |
Off label use | 673.95 | 11.25 | 1203 | 244573 | 418321 | 34292834 |
Drug ineffective | 600.46 | 11.25 | 1468 | 244308 | 455283 | 34255872 |
Myopathy | 525.15 | 11.25 | 519 | 245257 | 11035 | 34700120 |
Drug interaction | 430.26 | 11.25 | 2888 | 242888 | 223058 | 34488097 |
Drug abuse | 429.48 | 11.25 | 87 | 245689 | 99009 | 34612146 |
Myocardial infarction | 329.89 | 11.25 | 1702 | 244074 | 119383 | 34591772 |
Febrile neutropenia | 300.79 | 11.25 | 311 | 245465 | 136538 | 34574617 |
Acute kidney injury | 288.72 | 11.25 | 3343 | 242433 | 301645 | 34409510 |
Product use in unapproved indication | 272.04 | 11.25 | 255 | 245521 | 117244 | 34593911 |
Toxicity to various agents | 261.83 | 11.25 | 644 | 245132 | 199718 | 34511437 |
Coronary artery disease | 239.37 | 11.25 | 816 | 244960 | 47489 | 34663666 |
Tendon rupture | 235.14 | 11.25 | 268 | 245508 | 6744 | 34704411 |
Foetal exposure during pregnancy | 221.90 | 11.25 | 11 | 245765 | 38090 | 34673065 |
Myositis | 221.07 | 11.25 | 343 | 245433 | 11727 | 34699428 |
Muscular weakness | 195.02 | 11.25 | 1020 | 244756 | 71877 | 34639278 |
Death | 194.00 | 11.25 | 1828 | 243948 | 396221 | 34314934 |
Treatment failure | 178.82 | 11.25 | 53 | 245723 | 46644 | 34664511 |
Cerebrovascular accident | 175.95 | 11.25 | 1109 | 244667 | 83702 | 34627453 |
Neutropenia | 172.63 | 11.25 | 547 | 245229 | 156231 | 34554924 |
Pyrexia | 152.89 | 11.25 | 1551 | 244225 | 331462 | 34379693 |
Dizziness | 150.06 | 11.25 | 2261 | 243515 | 216260 | 34494895 |
Syncope | 148.37 | 11.25 | 1126 | 244650 | 90325 | 34620830 |
Immune-mediated myositis | 136.66 | 11.25 | 115 | 245661 | 1968 | 34709187 |
General physical health deterioration | 133.49 | 11.25 | 1434 | 244342 | 126835 | 34584320 |
Angina pectoris | 131.65 | 11.25 | 502 | 245274 | 30861 | 34680294 |
Therapeutic product effect incomplete | 126.17 | 11.25 | 102 | 245674 | 50439 | 34660716 |
Muscle rupture | 117.17 | 11.25 | 110 | 245666 | 2188 | 34708967 |
Drug resistance | 115.96 | 11.25 | 21 | 245755 | 25906 | 34685249 |
Infusion related reaction | 111.49 | 11.25 | 125 | 245651 | 52932 | 34658223 |
Cytomegalovirus infection | 106.96 | 11.25 | 26 | 245750 | 26109 | 34685046 |
Chromaturia | 106.69 | 11.25 | 282 | 245494 | 14238 | 34696917 |
Product use issue | 105.57 | 11.25 | 176 | 245600 | 63040 | 34648115 |
Premature baby | 101.82 | 11.25 | 10 | 245766 | 19623 | 34691532 |
Malignant neoplasm progression | 101.21 | 11.25 | 301 | 245475 | 87745 | 34623410 |
Liver function test abnormal | 101.09 | 11.25 | 460 | 245316 | 30614 | 34680541 |
Transient ischaemic attack | 100.67 | 11.25 | 423 | 245353 | 27190 | 34683965 |
International normalised ratio increased | 100.64 | 11.25 | 623 | 245153 | 46704 | 34664451 |
Cardiac failure congestive | 100.50 | 11.25 | 960 | 244816 | 82310 | 34628845 |
Intentional product use issue | 97.61 | 11.25 | 169 | 245607 | 59647 | 34651508 |
Hospitalisation | 92.64 | 11.25 | 161 | 245615 | 56741 | 34654414 |
Septic shock | 90.41 | 11.25 | 235 | 245541 | 71599 | 34639556 |
Pneumonia | 88.18 | 11.25 | 1912 | 243864 | 360715 | 34350440 |
Myocardial ischaemia | 85.22 | 11.25 | 293 | 245483 | 17115 | 34694040 |
Drug dependence | 84.81 | 11.25 | 32 | 245744 | 24185 | 34686970 |
Asthenia | 83.27 | 11.25 | 2285 | 243491 | 242966 | 34468189 |
Fall | 82.61 | 11.25 | 1937 | 243839 | 200948 | 34510207 |
Chest pain | 81.20 | 11.25 | 1297 | 244479 | 125465 | 34585690 |
Lip swelling | 80.78 | 11.25 | 273 | 245503 | 15807 | 34695348 |
Muscle spasms | 80.50 | 11.25 | 844 | 244932 | 74157 | 34636998 |
Self esteem decreased | 80.21 | 11.25 | 49 | 245727 | 490 | 34710665 |
Product dose omission issue | 79.44 | 11.25 | 504 | 245272 | 119207 | 34591948 |
Acute myocardial infarction | 78.56 | 11.25 | 646 | 245130 | 53073 | 34658082 |
COVID-19 | 77.45 | 11.25 | 282 | 245494 | 77268 | 34633887 |
Drug reaction with eosinophilia and systemic symptoms | 74.71 | 11.25 | 73 | 245703 | 32939 | 34678216 |
Blood glucose increased | 74.06 | 11.25 | 756 | 245020 | 65962 | 34645193 |
Disease progression | 73.79 | 11.25 | 451 | 245325 | 107626 | 34603529 |
Product prescribing error | 72.78 | 11.25 | 337 | 245439 | 22590 | 34688565 |
Drug ineffective for unapproved indication | 72.57 | 11.25 | 38 | 245738 | 23677 | 34687478 |
Myelosuppression | 71.69 | 11.25 | 23 | 245753 | 19242 | 34691913 |
Angioedema | 70.27 | 11.25 | 477 | 245299 | 36897 | 34674258 |
Bronchopulmonary aspergillosis | 69.76 | 11.25 | 10 | 245766 | 14649 | 34696506 |
Mucosal inflammation | 68.75 | 11.25 | 103 | 245673 | 38519 | 34672636 |
Thrombocytopenia | 66.84 | 11.25 | 739 | 245037 | 155508 | 34555647 |
Gastrointestinal haemorrhage | 66.65 | 11.25 | 931 | 244845 | 87546 | 34623609 |
Pancytopenia | 66.57 | 11.25 | 394 | 245382 | 94763 | 34616392 |
Inappropriate schedule of product administration | 65.92 | 11.25 | 221 | 245555 | 62075 | 34649080 |
Pneumocystis jirovecii pneumonia | 65.82 | 11.25 | 28 | 245748 | 19682 | 34691473 |
Sleep terror | 63.59 | 11.25 | 80 | 245696 | 2238 | 34708917 |
Cardiospasm | 62.45 | 11.25 | 66 | 245710 | 1522 | 34709633 |
Balance disorder | 62.20 | 11.25 | 494 | 245282 | 40160 | 34670995 |
Nasopharyngitis | 61.87 | 11.25 | 267 | 245509 | 69701 | 34641454 |
Rheumatoid arthritis | 60.59 | 11.25 | 110 | 245666 | 38128 | 34673027 |
Carotid artery occlusion | 59.94 | 11.25 | 100 | 245676 | 3637 | 34707518 |
Oxygen saturation decreased | 59.66 | 11.25 | 187 | 245589 | 53631 | 34657524 |
Dyspnoea | 58.00 | 11.25 | 3219 | 242557 | 373563 | 34337592 |
Quality of life decreased | 57.53 | 11.25 | 102 | 245674 | 3899 | 34707256 |
Completed suicide | 57.34 | 11.25 | 429 | 245347 | 97739 | 34613416 |
Leukopenia | 56.72 | 11.25 | 238 | 245538 | 62618 | 34648537 |
Amnesia | 56.03 | 11.25 | 349 | 245427 | 26214 | 34684941 |
Hepatic function abnormal | 55.90 | 11.25 | 145 | 245631 | 44218 | 34666937 |
Pruritus genital | 55.64 | 11.25 | 73 | 245703 | 2131 | 34709024 |
Confusional state | 55.15 | 11.25 | 1365 | 244411 | 142795 | 34568360 |
Tension headache | 55.07 | 11.25 | 86 | 245690 | 2956 | 34708199 |
Idiopathic pulmonary fibrosis | 53.29 | 11.25 | 92 | 245684 | 3442 | 34707713 |
Condition aggravated | 52.63 | 11.25 | 993 | 244783 | 191203 | 34519952 |
Coma | 52.57 | 11.25 | 156 | 245620 | 45522 | 34665633 |
Coronary artery stenosis | 52.55 | 11.25 | 168 | 245608 | 9448 | 34701707 |
Product monitoring error | 52.15 | 11.25 | 103 | 245673 | 4278 | 34706877 |
Bone marrow failure | 52.08 | 11.25 | 78 | 245698 | 29175 | 34681980 |
Therapeutic drug monitoring analysis not performed | 51.79 | 11.25 | 38 | 245738 | 527 | 34710628 |
Dermatomyositis | 51.66 | 11.25 | 54 | 245722 | 1229 | 34709926 |
Palmoplantar keratoderma | 51.36 | 11.25 | 66 | 245710 | 1887 | 34709268 |
Intentional overdose | 51.10 | 11.25 | 148 | 245628 | 43526 | 34667629 |
Subdural haemorrhage | 50.66 | 11.25 | 85 | 245691 | 3106 | 34708049 |
Coronary artery occlusion | 50.62 | 11.25 | 181 | 245595 | 10781 | 34700374 |
Muscle atrophy | 49.59 | 11.25 | 139 | 245637 | 7265 | 34703890 |
Agranulocytosis | 49.07 | 11.25 | 57 | 245719 | 23764 | 34687391 |
Orthostatic intolerance | 49.03 | 11.25 | 43 | 245733 | 780 | 34710375 |
Pathogen resistance | 48.72 | 11.25 | 5 | 245771 | 9477 | 34701678 |
Amyotrophic lateral sclerosis | 48.62 | 11.25 | 47 | 245729 | 971 | 34710184 |
Cytokine release syndrome | 47.93 | 11.25 | 54 | 245722 | 22823 | 34688332 |
Renal failure | 47.21 | 11.25 | 1227 | 244549 | 129330 | 34581825 |
Gait disturbance | 47.13 | 11.25 | 851 | 244925 | 84289 | 34626866 |
Atrial fibrillation | 47.12 | 11.25 | 1160 | 244616 | 121233 | 34589922 |
Synovitis | 46.94 | 11.25 | 20 | 245756 | 14046 | 34697109 |
Infection | 46.80 | 11.25 | 411 | 245365 | 90504 | 34620651 |
Appendicolith | 46.76 | 11.25 | 150 | 245626 | 8451 | 34702704 |
Palpitations | 46.72 | 11.25 | 458 | 245318 | 39528 | 34671627 |
Myoglobinuria | 46.61 | 11.25 | 41 | 245735 | 747 | 34710408 |
Respiratory depression | 45.48 | 11.25 | 29 | 245747 | 16216 | 34694939 |
Lactic acidosis | 44.98 | 11.25 | 407 | 245369 | 34365 | 34676790 |
Hypoglycaemia | 44.84 | 11.25 | 584 | 245192 | 54056 | 34657099 |
Social problem | 44.77 | 11.25 | 43 | 245733 | 881 | 34710274 |
Circulatory collapse | 44.73 | 11.25 | 277 | 245499 | 20761 | 34690394 |
Immunisation | 44.57 | 11.25 | 46 | 245730 | 1031 | 34710124 |
Venoocclusive liver disease | 44.23 | 11.25 | 3 | 245773 | 7963 | 34703192 |
Hyperkalaemia | 44.00 | 11.25 | 709 | 245067 | 68680 | 34642475 |
Blood creatinine increased | 43.99 | 11.25 | 924 | 244852 | 94052 | 34617103 |
Atrial tachycardia | 43.75 | 11.25 | 86 | 245690 | 3559 | 34707596 |
Blood urea abnormal | 43.75 | 11.25 | 40 | 245736 | 768 | 34710387 |
Dehydration | 43.43 | 11.25 | 1209 | 244567 | 128760 | 34582395 |
Poisoning deliberate | 43.42 | 11.25 | 3 | 245773 | 7841 | 34703314 |
Angina unstable | 42.84 | 11.25 | 179 | 245597 | 11474 | 34699681 |
Stomatitis | 42.82 | 11.25 | 154 | 245622 | 42360 | 34668795 |
Thrombotic microangiopathy | 42.67 | 11.25 | 11 | 245765 | 10619 | 34700536 |
Haemophagocytic lymphohistiocytosis | 42.42 | 11.25 | 19 | 245757 | 12954 | 34698201 |
Pseudomonas infection | 42.30 | 11.25 | 17 | 245759 | 12365 | 34698790 |
Therapy non-responder | 42.00 | 11.25 | 138 | 245638 | 39008 | 34672147 |
Epstein-Barr virus infection | 41.99 | 11.25 | 3 | 245773 | 7625 | 34703530 |
Cardiovascular disorder | 41.39 | 11.25 | 160 | 245616 | 9896 | 34701259 |
Low birth weight baby | 41.06 | 11.25 | 4 | 245772 | 7901 | 34703254 |
Erectile dysfunction | 40.96 | 11.25 | 267 | 245509 | 20370 | 34690785 |
Nightmare | 40.95 | 11.25 | 205 | 245571 | 14186 | 34696969 |
Transplant rejection | 40.76 | 11.25 | 11 | 245765 | 10300 | 34700855 |
Posterior reversible encephalopathy syndrome | 40.54 | 11.25 | 10 | 245766 | 9944 | 34701211 |
Anosmia | 40.16 | 11.25 | 88 | 245688 | 3936 | 34707219 |
Abnormal dreams | 40.15 | 11.25 | 131 | 245645 | 7447 | 34703708 |
Pancreatitis acute | 39.83 | 11.25 | 336 | 245440 | 27805 | 34683350 |
Haematuria | 39.37 | 11.25 | 531 | 245245 | 49535 | 34661620 |
Neutrophil count decreased | 39.32 | 11.25 | 205 | 245571 | 50899 | 34660256 |
Cardio-respiratory arrest | 39.09 | 11.25 | 228 | 245548 | 55045 | 34656110 |
White blood cell count decreased | 38.97 | 11.25 | 456 | 245320 | 94989 | 34616166 |
Neoplasm progression | 38.75 | 11.25 | 65 | 245711 | 23235 | 34687920 |
Tumour lysis syndrome | 38.28 | 11.25 | 38 | 245738 | 17021 | 34694134 |
Haematotoxicity | 38.04 | 11.25 | 6 | 245770 | 8188 | 34702967 |
Cytopenia | 38.03 | 11.25 | 21 | 245755 | 12702 | 34698453 |
Blood pressure fluctuation | 37.07 | 11.25 | 76 | 245700 | 25173 | 34685982 |
Aspergillus infection | 36.96 | 11.25 | 20 | 245756 | 12234 | 34698921 |
Substance abuse | 36.86 | 11.25 | 5 | 245771 | 7636 | 34703519 |
Platelet count decreased | 36.72 | 11.25 | 606 | 245170 | 119111 | 34592044 |
Influenza | 36.67 | 11.25 | 202 | 245574 | 49464 | 34661691 |
Suicide attempt | 35.97 | 11.25 | 147 | 245629 | 38969 | 34672186 |
Facial pain | 35.83 | 11.25 | 80 | 245696 | 3624 | 34707531 |
Joint swelling | 35.78 | 11.25 | 260 | 245516 | 59630 | 34651525 |
Pain in extremity | 35.55 | 11.25 | 1152 | 244624 | 125361 | 34585794 |
Muscle disorder | 35.37 | 11.25 | 65 | 245711 | 2556 | 34708599 |
Muscle necrosis | 35.15 | 11.25 | 37 | 245739 | 849 | 34710306 |
Actinic keratosis | 34.88 | 11.25 | 90 | 245686 | 4477 | 34706678 |
Ischaemic cardiomyopathy | 34.35 | 11.25 | 111 | 245665 | 6278 | 34704877 |
Accidental exposure to product | 34.29 | 11.25 | 24 | 245752 | 12778 | 34698377 |
Swollen tongue | 34.06 | 11.25 | 197 | 245579 | 14408 | 34696747 |
Subarachnoid haemorrhage | 33.87 | 11.25 | 177 | 245599 | 12458 | 34698697 |
Injection site pain | 33.77 | 11.25 | 150 | 245626 | 38855 | 34672300 |
Immune reconstitution inflammatory syndrome | 33.41 | 11.25 | 10 | 245766 | 8749 | 34702406 |
Bradycardia | 33.39 | 11.25 | 729 | 245047 | 74689 | 34636466 |
Tendonitis | 33.29 | 11.25 | 140 | 245636 | 9000 | 34702155 |
Therapeutic response shortened | 33.10 | 11.25 | 6 | 245770 | 7398 | 34703757 |
Asthma | 32.87 | 11.25 | 171 | 245605 | 42485 | 34668670 |
Ventricular tachycardia | 32.30 | 11.25 | 307 | 245469 | 26272 | 34684883 |
Obstructive airways disorder | 31.99 | 11.25 | 37 | 245739 | 15457 | 34695698 |
Naevus flammeus | 31.96 | 11.25 | 19 | 245757 | 180 | 34710975 |
Contraindicated product prescribed | 31.51 | 11.25 | 25 | 245751 | 392 | 34710763 |
Carotid artery stenosis | 31.45 | 11.25 | 92 | 245684 | 4927 | 34706228 |
Myoglobin blood increased | 31.18 | 11.25 | 67 | 245709 | 2956 | 34708199 |
Atrial septal defect | 30.94 | 11.25 | 7 | 245769 | 7385 | 34703770 |
Haemodialysis | 30.70 | 11.25 | 151 | 245625 | 10375 | 34700780 |
Pancreatitis necrotising | 30.63 | 11.25 | 63 | 245713 | 2695 | 34708460 |
Encephalopathy | 30.47 | 11.25 | 136 | 245640 | 35183 | 34675972 |
Clostridium difficile infection | 30.26 | 11.25 | 54 | 245722 | 18844 | 34692311 |
Altered state of consciousness | 30.25 | 11.25 | 73 | 245703 | 22820 | 34688335 |
Hepatitis C | 29.71 | 11.25 | 16 | 245760 | 9814 | 34701341 |
Disseminated intravascular coagulation | 29.28 | 11.25 | 69 | 245707 | 21747 | 34689408 |
Pelvic mass | 29.21 | 11.25 | 19 | 245757 | 214 | 34710941 |
Aplastic anaemia | 29.09 | 11.25 | 16 | 245760 | 9700 | 34701455 |
Pulmonary fibrosis | 28.93 | 11.25 | 225 | 245551 | 18171 | 34692984 |
Productive cough | 28.90 | 11.25 | 152 | 245624 | 37661 | 34673494 |
Psychiatric symptom | 28.67 | 11.25 | 71 | 245705 | 3442 | 34707713 |
Lymphopenia | 28.64 | 11.25 | 44 | 245732 | 16291 | 34694864 |
Bursitis | 28.60 | 11.25 | 94 | 245682 | 5364 | 34705791 |
Febrile bone marrow aplasia | 28.49 | 11.25 | 11 | 245765 | 8198 | 34702957 |
Serotonin syndrome | 28.42 | 11.25 | 61 | 245715 | 19872 | 34691283 |
Hepatic encephalopathy | 28.29 | 11.25 | 37 | 245739 | 14648 | 34696507 |
Overdose | 28.22 | 11.25 | 460 | 245316 | 90599 | 34620556 |
Mucosal haemorrhage | 28.12 | 11.25 | 45 | 245731 | 1580 | 34709575 |
Blood urea increased | 28.12 | 11.25 | 332 | 245444 | 30032 | 34681123 |
Ischaemic stroke | 28.03 | 11.25 | 222 | 245554 | 18028 | 34693127 |
Gait inability | 27.88 | 11.25 | 245 | 245531 | 20513 | 34690642 |
Drug intolerance | 27.76 | 11.25 | 276 | 245500 | 59294 | 34651861 |
Myxoedema coma | 27.71 | 11.25 | 20 | 245756 | 270 | 34710885 |
Hypogammaglobulinaemia | 27.48 | 11.25 | 10 | 245766 | 7730 | 34703425 |
Pain of skin | 27.47 | 11.25 | 100 | 245676 | 6009 | 34705146 |
Adrenal insufficiency | 27.46 | 11.25 | 35 | 245741 | 14012 | 34697143 |
Muscle twitching | 27.42 | 11.25 | 144 | 245632 | 10154 | 34701001 |
Faeces pale | 27.28 | 11.25 | 41 | 245735 | 1362 | 34709793 |
Intestinal obstruction | 26.94 | 11.25 | 77 | 245699 | 22745 | 34688410 |
Oedema mouth | 26.93 | 11.25 | 39 | 245737 | 1252 | 34709903 |
Seizure | 26.75 | 11.25 | 548 | 245228 | 104309 | 34606846 |
Injury | 26.68 | 11.25 | 242 | 245534 | 20445 | 34690710 |
Neurotoxicity | 26.62 | 11.25 | 54 | 245722 | 17956 | 34693199 |
Respiratory failure | 26.36 | 11.25 | 572 | 245204 | 108000 | 34603155 |
Blood glucose fluctuation | 26.18 | 11.25 | 75 | 245701 | 3969 | 34707186 |
Status epilepticus | 26.18 | 11.25 | 30 | 245746 | 12584 | 34698571 |
Illness | 26.15 | 11.25 | 34 | 245742 | 13495 | 34697660 |
Myopathy toxic | 26.02 | 11.25 | 26 | 245750 | 560 | 34710595 |
Atrioventricular block complete | 25.99 | 11.25 | 132 | 245644 | 9187 | 34701968 |
Urogenital haemorrhage | 25.87 | 11.25 | 29 | 245747 | 716 | 34710439 |
Gastritis erosive | 25.75 | 11.25 | 96 | 245680 | 5836 | 34705319 |
Cytomegalovirus viraemia | 25.71 | 11.25 | 10 | 245766 | 7420 | 34703735 |
Fear | 25.54 | 11.25 | 143 | 245633 | 10333 | 34700822 |
Lymphocyte count decreased | 25.49 | 11.25 | 78 | 245698 | 22544 | 34688611 |
Actinic elastosis | 25.47 | 11.25 | 11 | 245765 | 48 | 34711107 |
Therapeutic product effect decreased | 25.27 | 11.25 | 142 | 245634 | 34601 | 34676554 |
Pancreatitis | 25.25 | 11.25 | 399 | 245377 | 38492 | 34672663 |
Transient global amnesia | 25.21 | 11.25 | 21 | 245755 | 354 | 34710801 |
Bacteraemia | 25.17 | 11.25 | 64 | 245712 | 19653 | 34691502 |
No adverse event | 25.16 | 11.25 | 80 | 245696 | 22847 | 34688308 |
Orthostatic hypotension | 25.16 | 11.25 | 286 | 245490 | 25633 | 34685522 |
Atrioventricular block first degree | 25.13 | 11.25 | 97 | 245679 | 5995 | 34705160 |
Polymyositis | 24.82 | 11.25 | 40 | 245736 | 1413 | 34709742 |
Akathisia | 24.80 | 11.25 | 13 | 245763 | 8096 | 34703059 |
Weight increased | 24.69 | 11.25 | 483 | 245293 | 92550 | 34618605 |
Neuropathy peripheral | 24.69 | 11.25 | 424 | 245352 | 82839 | 34628316 |
Cystitis haemorrhagic | 24.54 | 11.25 | 5 | 245771 | 5674 | 34705481 |
Hyperbilirubinaemia | 24.47 | 11.25 | 51 | 245725 | 16792 | 34694363 |
Stress | 24.32 | 11.25 | 323 | 245453 | 30024 | 34681131 |
Myasthenia gravis | 24.27 | 11.25 | 105 | 245671 | 6835 | 34704320 |
Therapeutic response decreased | 24.02 | 11.25 | 115 | 245661 | 29198 | 34681957 |
Hyponatraemia | 23.99 | 11.25 | 756 | 245020 | 81935 | 34629220 |
Sedation | 23.97 | 11.25 | 72 | 245704 | 20934 | 34690221 |
Diplopia | 23.78 | 11.25 | 201 | 245575 | 16642 | 34694513 |
Poor venous access | 23.61 | 11.25 | 4 | 245772 | 5179 | 34705976 |
Compartment syndrome | 23.59 | 11.25 | 60 | 245716 | 2958 | 34708197 |
Alveolitis | 23.47 | 11.25 | 43 | 245733 | 1687 | 34709468 |
Oesophageal obstruction | 23.41 | 11.25 | 23 | 245753 | 485 | 34710670 |
Arteriosclerosis | 23.23 | 11.25 | 154 | 245622 | 11814 | 34699341 |
Hyperthermia | 23.23 | 11.25 | 24 | 245752 | 10553 | 34700602 |
Cytomegalovirus infection reactivation | 23.20 | 11.25 | 4 | 245772 | 5114 | 34706041 |
Ventricular fibrillation | 23.06 | 11.25 | 255 | 245521 | 22699 | 34688456 |
Hepatocellular carcinoma | 23.02 | 11.25 | 12 | 245764 | 7497 | 34703658 |
BK virus infection | 22.91 | 11.25 | 6 | 245770 | 5732 | 34705423 |
Product complaint | 22.85 | 11.25 | 92 | 245684 | 5798 | 34705357 |
Dialysis | 22.85 | 11.25 | 146 | 245630 | 11062 | 34700093 |
Klebsiella infection | 22.84 | 11.25 | 16 | 245760 | 8515 | 34702640 |
Blood electrolytes abnormal | 22.81 | 11.25 | 31 | 245745 | 937 | 34710218 |
Tenderness | 22.80 | 11.25 | 103 | 245673 | 6831 | 34704324 |
Necrotising myositis | 22.66 | 11.25 | 26 | 245750 | 659 | 34710496 |
Diverticulum | 22.55 | 11.25 | 105 | 245671 | 7054 | 34704101 |
Osteochondrosis | 22.39 | 11.25 | 33 | 245743 | 1077 | 34710078 |
Renal injury | 22.31 | 11.25 | 145 | 245631 | 11050 | 34700105 |
Disease recurrence | 22.20 | 11.25 | 77 | 245699 | 21413 | 34689742 |
Ankylosing spondylitis | 22.11 | 11.25 | 6 | 245770 | 5598 | 34705557 |
Nocturia | 22.06 | 11.25 | 135 | 245641 | 10075 | 34701080 |
Hyperlipidaemia | 21.91 | 11.25 | 176 | 245600 | 14353 | 34696802 |
Abdominal pain lower | 21.73 | 11.25 | 138 | 245638 | 10433 | 34700722 |
Brain oedema | 21.68 | 11.25 | 40 | 245736 | 13781 | 34697374 |
Mitochondrial myopathy | 21.58 | 11.25 | 15 | 245761 | 190 | 34710965 |
Eye pruritus | 21.53 | 11.25 | 107 | 245669 | 7382 | 34703773 |
Acute coronary syndrome | 21.48 | 11.25 | 166 | 245610 | 13379 | 34697776 |
Loss of personal independence in daily activities | 21.31 | 11.25 | 141 | 245635 | 33038 | 34678117 |
Respiratory arrest | 21.28 | 11.25 | 113 | 245663 | 27930 | 34683225 |
Granuloma annulare | 21.28 | 11.25 | 14 | 245762 | 161 | 34710994 |
Blood pressure systolic increased | 21.26 | 11.25 | 86 | 245690 | 22866 | 34688289 |
Biliary cirrhosis | 21.08 | 11.25 | 12 | 245764 | 104 | 34711051 |
Hepatic cytolysis | 20.97 | 11.25 | 44 | 245732 | 14452 | 34696703 |
Asphyxia | 20.84 | 11.25 | 11 | 245765 | 6824 | 34704331 |
Ejaculation failure | 20.74 | 11.25 | 27 | 245749 | 782 | 34710373 |
Syringe issue | 20.66 | 11.25 | 7 | 245769 | 5657 | 34705498 |
Wrong technique in product usage process | 20.64 | 11.25 | 158 | 245618 | 35828 | 34675327 |
Acute myeloid leukaemia | 20.58 | 11.25 | 63 | 245713 | 18207 | 34692948 |
Sepsis | 20.57 | 11.25 | 959 | 244817 | 165602 | 34545553 |
Mitochondrial myopathy acquired | 20.49 | 11.25 | 7 | 245769 | 13 | 34711142 |
Brain scan abnormal | 20.46 | 11.25 | 28 | 245748 | 852 | 34710303 |
Tinnitus | 20.44 | 11.25 | 224 | 245552 | 19894 | 34691261 |
Hiatus hernia | 20.42 | 11.25 | 107 | 245669 | 7538 | 34703617 |
Psoriatic arthropathy | 20.41 | 11.25 | 71 | 245705 | 19727 | 34691428 |
Respiratory tract haemorrhage | 20.39 | 11.25 | 34 | 245742 | 1236 | 34709919 |
Thrombotic thrombocytopenic purpura | 20.38 | 11.25 | 61 | 245715 | 3309 | 34707846 |
Contusion | 20.28 | 11.25 | 364 | 245412 | 36000 | 34675155 |
Glycosylated haemoglobin increased | 20.17 | 11.25 | 143 | 245633 | 11217 | 34699938 |
Duodenal ulcer | 20.09 | 11.25 | 133 | 245643 | 10199 | 34700956 |
Appendicitis | 20.01 | 11.25 | 175 | 245601 | 14632 | 34696523 |
Haematoma | 19.89 | 11.25 | 271 | 245505 | 25334 | 34685821 |
Myoglobin urine | 19.84 | 11.25 | 7 | 245769 | 15 | 34711140 |
Upper motor neurone lesion | 19.81 | 11.25 | 12 | 245764 | 118 | 34711037 |
Personality change | 19.72 | 11.25 | 80 | 245696 | 5059 | 34706096 |
Occupational problem environmental | 19.67 | 11.25 | 6 | 245770 | 6 | 34711149 |
Avoidant personality disorder | 19.67 | 11.25 | 6 | 245770 | 6 | 34711149 |
Pemphigoid | 19.63 | 11.25 | 116 | 245660 | 8550 | 34702605 |
Atrioventricular block | 19.61 | 11.25 | 110 | 245666 | 7953 | 34703202 |
High density lipoprotein decreased | 19.55 | 11.25 | 60 | 245716 | 3300 | 34707855 |
Viral myositis | 19.54 | 11.25 | 7 | 245769 | 16 | 34711139 |
Potentiating drug interaction | 19.52 | 11.25 | 78 | 245698 | 4899 | 34706256 |
Pallor | 19.51 | 11.25 | 269 | 245507 | 25211 | 34685944 |
Social avoidant behaviour | 19.44 | 11.25 | 57 | 245719 | 3057 | 34708098 |
Pneumonia fungal | 19.43 | 11.25 | 13 | 245763 | 7087 | 34704068 |
Hypoalbuminaemia | 19.30 | 11.25 | 35 | 245741 | 12139 | 34699016 |
Full blood count abnormal | 19.21 | 11.25 | 67 | 245709 | 18601 | 34692554 |
Pneumonia aspiration | 19.16 | 11.25 | 195 | 245581 | 41708 | 34669447 |
Lung disorder | 19.12 | 11.25 | 154 | 245622 | 34542 | 34676613 |
Hypertensive crisis | 19.09 | 11.25 | 116 | 245660 | 8635 | 34702520 |
Spinal cord haemorrhage | 19.05 | 11.25 | 17 | 245759 | 316 | 34710839 |
Enterocolitis | 19.04 | 11.25 | 17 | 245759 | 8009 | 34703146 |
Device related infection | 19.02 | 11.25 | 60 | 245716 | 17177 | 34693978 |
Lethargy | 18.99 | 11.25 | 400 | 245376 | 40722 | 34670433 |
Emotional distress | 18.98 | 11.25 | 175 | 245601 | 14851 | 34696304 |
Intentional product misuse | 18.95 | 11.25 | 217 | 245559 | 45394 | 34665761 |
Renal cyst | 18.87 | 11.25 | 119 | 245657 | 8974 | 34702181 |
Malnutrition | 18.87 | 11.25 | 38 | 245738 | 12671 | 34698484 |
Prostate cancer recurrent | 18.84 | 11.25 | 29 | 245747 | 984 | 34710171 |
Anhedonia | 18.80 | 11.25 | 104 | 245672 | 7481 | 34703674 |
Sickle cell anaemia with crisis | 18.74 | 11.25 | 3 | 245773 | 4050 | 34707105 |
Respiratory syncytial virus infection | 18.66 | 11.25 | 5 | 245771 | 4704 | 34706451 |
Therapy interrupted | 18.64 | 11.25 | 43 | 245733 | 13654 | 34697501 |
Myoglobin urine present | 18.61 | 11.25 | 13 | 245763 | 166 | 34710989 |
Blood glucose abnormal | 18.53 | 11.25 | 87 | 245689 | 5865 | 34705290 |
Ventricular septal defect | 18.42 | 11.25 | 3 | 245773 | 3998 | 34707157 |
Frequent bowel movements | 18.34 | 11.25 | 39 | 245737 | 12748 | 34698407 |
Impaired quality of life | 18.28 | 11.25 | 9 | 245767 | 5809 | 34705346 |
Carcinogenicity | 18.28 | 11.25 | 9 | 245767 | 56 | 34711099 |
Platelet count normal | 18.20 | 11.25 | 7 | 245769 | 21 | 34711134 |
Oedema peripheral | 18.18 | 11.25 | 1023 | 244753 | 118789 | 34592366 |
Arteriosclerosis coronary artery | 18.16 | 11.25 | 150 | 245626 | 12335 | 34698820 |
Acquired claw toe | 18.16 | 11.25 | 8 | 245768 | 37 | 34711118 |
Spinal osteoarthritis | 18.15 | 11.25 | 104 | 245672 | 7579 | 34703576 |
Periarthritis calcarea | 18.13 | 11.25 | 10 | 245766 | 81 | 34711074 |
Hypoglycaemic unconsciousness | 17.97 | 11.25 | 25 | 245751 | 773 | 34710382 |
Incorrect dose administered | 17.93 | 11.25 | 190 | 245586 | 40325 | 34670830 |
Sinus bradycardia | 17.93 | 11.25 | 154 | 245622 | 12809 | 34698346 |
Type 2 diabetes mellitus | 17.93 | 11.25 | 182 | 245594 | 15850 | 34695305 |
Interstitial lung disease | 17.91 | 11.25 | 337 | 245439 | 64945 | 34646210 |
Sudden cardiac death | 17.85 | 11.25 | 62 | 245714 | 3639 | 34707516 |
Abdominal pain upper | 17.79 | 11.25 | 642 | 245134 | 70848 | 34640307 |
Poisoning | 17.78 | 11.25 | 37 | 245739 | 12189 | 34698966 |
Arrhythmia | 17.76 | 11.25 | 352 | 245424 | 35456 | 34675699 |
Osteonecrosis | 17.75 | 11.25 | 50 | 245726 | 14840 | 34696315 |
Lichen planus | 17.75 | 11.25 | 28 | 245748 | 971 | 34710184 |
Malignant spinal cord compression | 17.74 | 11.25 | 12 | 245764 | 145 | 34711010 |
Hepatitis B | 17.70 | 11.25 | 10 | 245766 | 5973 | 34705182 |
Feeding disorder | 17.67 | 11.25 | 14 | 245762 | 6996 | 34704159 |
Eosinophilia | 17.57 | 11.25 | 110 | 245666 | 26112 | 34685043 |
Hypoxia | 17.50 | 11.25 | 277 | 245499 | 54818 | 34656337 |
Nephrolithiasis | 17.48 | 11.25 | 133 | 245643 | 30200 | 34680955 |
Central nervous system lesion | 17.47 | 11.25 | 12 | 245764 | 6451 | 34704704 |
Vascular device infection | 17.44 | 11.25 | 4 | 245772 | 4181 | 34706974 |
Rash | 17.44 | 11.25 | 1339 | 244437 | 221413 | 34489742 |
Aortic valve sclerosis | 17.43 | 11.25 | 28 | 245748 | 986 | 34710169 |
Chronic obstructive pulmonary disease | 17.43 | 11.25 | 459 | 245317 | 48459 | 34662696 |
Haemorrhage intracranial | 17.34 | 11.25 | 180 | 245596 | 15766 | 34695389 |
Ischaemia | 17.34 | 11.25 | 71 | 245705 | 4509 | 34706646 |
Extremity necrosis | 17.32 | 11.25 | 41 | 245735 | 1931 | 34709224 |
Multiple injuries | 17.30 | 11.25 | 40 | 245736 | 1855 | 34709300 |
Serum ferritin abnormal | 17.21 | 11.25 | 14 | 245762 | 228 | 34710927 |
Gastritis | 17.19 | 11.25 | 232 | 245544 | 21641 | 34689514 |
Cerebral haemorrhage | 17.18 | 11.25 | 343 | 245433 | 34594 | 34676561 |
Blood glucose decreased | 17.14 | 11.25 | 155 | 245621 | 13082 | 34698073 |
Vasculitis | 17.12 | 11.25 | 137 | 245639 | 11159 | 34699996 |
Low density lipoprotein increased | 16.98 | 11.25 | 69 | 245707 | 4367 | 34706788 |
Contracted bladder | 16.96 | 11.25 | 6 | 245770 | 13 | 34711142 |
Swelling face | 16.92 | 11.25 | 242 | 245534 | 22863 | 34688292 |
Cerebral artery thrombosis | 16.91 | 11.25 | 24 | 245752 | 756 | 34710399 |
Blood loss anaemia | 16.86 | 11.25 | 107 | 245669 | 8087 | 34703068 |
Ventricular extrasystoles | 16.79 | 11.25 | 143 | 245633 | 11865 | 34699290 |
Raynaud's phenomenon | 16.75 | 11.25 | 15 | 245761 | 280 | 34710875 |
Peripheral vascular disorder | 16.70 | 11.25 | 75 | 245701 | 4961 | 34706194 |
Liver disorder | 16.60 | 11.25 | 150 | 245626 | 32847 | 34678308 |
Intentional self-injury | 16.59 | 11.25 | 46 | 245730 | 13725 | 34697430 |
Depressed level of consciousness | 16.58 | 11.25 | 207 | 245569 | 42634 | 34668521 |
Dilatation atrial | 16.47 | 11.25 | 41 | 245735 | 1994 | 34709161 |
Pleurothotonus | 16.41 | 11.25 | 30 | 245746 | 1175 | 34709980 |
Cognitive disorder | 16.28 | 11.25 | 288 | 245488 | 28405 | 34682750 |
Gynaecomastia | 16.28 | 11.25 | 125 | 245651 | 10055 | 34701100 |
Subdural haematoma | 16.22 | 11.25 | 217 | 245559 | 20204 | 34690951 |
Herpes zoster | 16.18 | 11.25 | 159 | 245617 | 34240 | 34676915 |
Hemiparesis | 16.18 | 11.25 | 176 | 245600 | 15602 | 34695553 |
Angioplasty | 16.16 | 11.25 | 27 | 245749 | 983 | 34710172 |
Maternal drugs affecting foetus | 16.11 | 11.25 | 4 | 245772 | 3961 | 34707194 |
Anal fistula | 16.01 | 11.25 | 9 | 245767 | 5390 | 34705765 |
Coagulation time prolonged | 15.97 | 11.25 | 31 | 245745 | 1271 | 34709884 |
Small for dates baby | 15.88 | 11.25 | 4 | 245772 | 3923 | 34707232 |
Lipase increased | 15.83 | 11.25 | 117 | 245659 | 9299 | 34701856 |
Blindness | 15.75 | 11.25 | 168 | 245608 | 14818 | 34696337 |
Sleep attacks | 15.72 | 11.25 | 11 | 245765 | 141 | 34711014 |
Hyperammonaemia | 15.69 | 11.25 | 13 | 245763 | 6354 | 34704801 |
Cytomegalovirus test positive | 15.64 | 11.25 | 4 | 245772 | 3882 | 34707273 |
Hyperhidrosis | 15.61 | 11.25 | 666 | 245110 | 75026 | 34636129 |
Radiation inflammation | 15.57 | 11.25 | 25 | 245751 | 880 | 34710275 |
Muscle discomfort | 15.57 | 11.25 | 10 | 245766 | 110 | 34711045 |
Injected limb mobility decreased | 15.49 | 11.25 | 5 | 245771 | 7 | 34711148 |
Pulmonary tuberculosis | 15.48 | 11.25 | 7 | 245769 | 4747 | 34706408 |
Infusion site pain | 15.43 | 11.25 | 4 | 245772 | 3847 | 34707308 |
Carpal tunnel syndrome | 15.39 | 11.25 | 70 | 245706 | 4656 | 34706499 |
Haematemesis | 15.32 | 11.25 | 277 | 245499 | 27434 | 34683721 |
Intermittent claudication | 15.30 | 11.25 | 43 | 245733 | 2251 | 34708904 |
Hepatic enzyme decreased | 15.24 | 11.25 | 8 | 245768 | 58 | 34711097 |
C-reactive protein increased | 15.23 | 11.25 | 278 | 245498 | 53820 | 34657335 |
Articular calcification | 15.16 | 11.25 | 9 | 245767 | 85 | 34711070 |
Second primary malignancy | 15.05 | 11.25 | 20 | 245756 | 7866 | 34703289 |
Pneumothorax | 15.01 | 11.25 | 76 | 245700 | 19016 | 34692139 |
Haematochezia | 14.99 | 11.25 | 431 | 245345 | 46103 | 34665052 |
Angioimmunoblastic T-cell lymphoma | 14.98 | 11.25 | 15 | 245761 | 324 | 34710831 |
Stent placement | 14.92 | 11.25 | 73 | 245703 | 5005 | 34706150 |
Gingival recession | 14.90 | 11.25 | 17 | 245759 | 428 | 34710727 |
Rash maculo-papular | 14.90 | 11.25 | 128 | 245648 | 28323 | 34682832 |
Therapy cessation | 14.85 | 11.25 | 65 | 245711 | 16908 | 34694247 |
Ventricular hypertrophy | 14.82 | 11.25 | 68 | 245708 | 4539 | 34706616 |
Areflexia | 14.82 | 11.25 | 51 | 245725 | 2980 | 34708175 |
Pneumonia bacterial | 14.80 | 11.25 | 39 | 245737 | 11833 | 34699322 |
Periprosthetic fracture | 14.79 | 11.25 | 11 | 245765 | 156 | 34710999 |
Carcinoma in situ | 14.74 | 11.25 | 5 | 245771 | 9 | 34711146 |
Blood lactic acid | 14.72 | 11.25 | 15 | 245761 | 331 | 34710824 |
Device issue | 14.72 | 11.25 | 29 | 245747 | 9748 | 34701407 |
Lichen myxoedematosus | 14.70 | 11.25 | 6 | 245770 | 22 | 34711133 |
Diabetes mellitus inadequate control | 14.65 | 11.25 | 152 | 245624 | 13312 | 34697843 |
Duodenitis | 14.61 | 11.25 | 70 | 245706 | 4758 | 34706397 |
Bone erosion | 14.58 | 11.25 | 5 | 245771 | 4010 | 34707145 |
Rhinorrhoea | 14.57 | 11.25 | 113 | 245663 | 25555 | 34685600 |
Aplasia | 14.56 | 11.25 | 7 | 245769 | 4581 | 34706574 |
Mitral valve incompetence | 14.55 | 11.25 | 165 | 245611 | 14778 | 34696377 |
Pneumonitis | 14.54 | 11.25 | 160 | 245616 | 33718 | 34677437 |
Vasculitic rash | 14.50 | 11.25 | 25 | 245751 | 934 | 34710221 |
Shock hypoglycaemic | 14.49 | 11.25 | 9 | 245767 | 93 | 34711062 |
Drug withdrawal syndrome | 14.45 | 11.25 | 81 | 245695 | 19753 | 34691402 |
Exercise lack of | 14.43 | 11.25 | 10 | 245766 | 126 | 34711029 |
Melaena | 14.40 | 11.25 | 338 | 245438 | 35042 | 34676113 |
Exposure to toxic agent | 14.38 | 11.25 | 4 | 245772 | 3671 | 34707484 |
Blood pressure diastolic abnormal | 14.33 | 11.25 | 8 | 245768 | 4810 | 34706345 |
Hepatitis | 14.31 | 11.25 | 242 | 245534 | 23662 | 34687493 |
Tongue oedema | 14.28 | 11.25 | 50 | 245726 | 2947 | 34708208 |
Accidental overdose | 14.27 | 11.25 | 83 | 245693 | 20057 | 34691098 |
Blood potassium increased | 14.24 | 11.25 | 178 | 245598 | 16317 | 34694838 |
Sinusitis | 14.23 | 11.25 | 205 | 245571 | 41197 | 34669958 |
Bradyphrenia | 14.22 | 11.25 | 8 | 245768 | 4790 | 34706365 |
Impatience | 14.22 | 11.25 | 15 | 245761 | 345 | 34710810 |
Candida infection | 14.22 | 11.25 | 70 | 245706 | 17645 | 34693510 |
Blood pressure systolic abnormal | 14.19 | 11.25 | 5 | 245771 | 3943 | 34707212 |
Blood pressure orthostatic | 14.18 | 11.25 | 8 | 245768 | 68 | 34711087 |
Mydriasis | 14.18 | 11.25 | 18 | 245758 | 7219 | 34703936 |
Musculoskeletal toxicity | 14.10 | 11.25 | 10 | 245766 | 131 | 34711024 |
Hepatic failure | 14.07 | 11.25 | 165 | 245611 | 34366 | 34676789 |
Drug specific antibody present | 13.97 | 11.25 | 3 | 245773 | 3282 | 34707873 |
Arteriosclerotic gangrene | 13.90 | 11.25 | 8 | 245768 | 71 | 34711084 |
Aphasia | 13.88 | 11.25 | 220 | 245556 | 21234 | 34689921 |
Cytomegalovirus chorioretinitis | 13.87 | 11.25 | 4 | 245772 | 3585 | 34707570 |
Basal ganglia haemorrhage | 13.82 | 11.25 | 24 | 245752 | 902 | 34710253 |
Methaemoglobinaemia | 13.82 | 11.25 | 4 | 245772 | 3577 | 34707578 |
Progressive multifocal leukoencephalopathy | 13.82 | 11.25 | 30 | 245746 | 9734 | 34701421 |
Miosis | 13.74 | 11.25 | 29 | 245747 | 9506 | 34701649 |
Polycystic liver disease | 13.71 | 11.25 | 9 | 245767 | 103 | 34711052 |
Oesophageal carcinoma | 13.66 | 11.25 | 28 | 245748 | 9276 | 34701879 |
Rash papular | 13.64 | 11.25 | 121 | 245655 | 10157 | 34700998 |
Social fear | 13.64 | 11.25 | 4 | 245772 | 3 | 34711152 |
Glycogen storage disease type II | 13.64 | 11.25 | 4 | 245772 | 3 | 34711152 |
Aortic aneurysm | 13.63 | 11.25 | 88 | 245688 | 6691 | 34704464 |
Blood phosphorus increased | 13.59 | 11.25 | 97 | 245679 | 7624 | 34703531 |
Eosinophilic cystitis | 13.58 | 11.25 | 6 | 245770 | 28 | 34711127 |
Wheezing | 13.54 | 11.25 | 207 | 245569 | 41195 | 34669960 |
Pseudoporphyria | 13.49 | 11.25 | 15 | 245761 | 367 | 34710788 |
Muscle fatigue | 13.46 | 11.25 | 31 | 245745 | 1434 | 34709721 |
Coordination abnormal | 13.44 | 11.25 | 96 | 245680 | 7548 | 34703607 |
Electrocardiogram abnormal | 13.40 | 11.25 | 111 | 245665 | 9136 | 34702019 |
Portal fibrosis | 13.38 | 11.25 | 14 | 245762 | 319 | 34710836 |
Fungal infection | 13.36 | 11.25 | 62 | 245714 | 15873 | 34695282 |
Blood creatine phosphokinase | 13.36 | 11.25 | 9 | 245767 | 108 | 34711047 |
Cardiotoxicity | 13.35 | 11.25 | 12 | 245764 | 5636 | 34705519 |
Cardiogenic shock | 13.31 | 11.25 | 262 | 245514 | 26356 | 34684799 |
Ureteric injury | 13.31 | 11.25 | 7 | 245769 | 51 | 34711104 |
Colitis | 13.30 | 11.25 | 186 | 245590 | 37564 | 34673591 |
Tuberculosis | 13.29 | 11.25 | 25 | 245751 | 8552 | 34702603 |
Dystonia | 13.24 | 11.25 | 36 | 245740 | 10809 | 34700346 |
Complications of transplanted kidney | 13.22 | 11.25 | 8 | 245768 | 4601 | 34706554 |
Cholecystitis chronic | 13.20 | 11.25 | 23 | 245753 | 867 | 34710288 |
Urinary incontinence | 13.15 | 11.25 | 196 | 245580 | 18678 | 34692477 |
Puncture site haematoma | 13.14 | 11.25 | 10 | 245766 | 147 | 34711008 |
Abscess | 13.13 | 11.25 | 41 | 245735 | 11776 | 34699379 |
Quadriparesis | 13.11 | 11.25 | 32 | 245744 | 1537 | 34709618 |
Pharyngeal oedema | 13.09 | 11.25 | 80 | 245696 | 5967 | 34705188 |
Gallbladder neoplasm | 13.09 | 11.25 | 6 | 245770 | 31 | 34711124 |
Electrolyte depletion | 13.08 | 11.25 | 11 | 245765 | 188 | 34710967 |
Nephropathy toxic | 13.07 | 11.25 | 45 | 245731 | 12543 | 34698612 |
Gout | 13.05 | 11.25 | 199 | 245577 | 19054 | 34692101 |
Rotator cuff syndrome | 13.04 | 11.25 | 76 | 245700 | 5573 | 34705582 |
Pancreatitis chronic | 13.03 | 11.25 | 40 | 245736 | 2200 | 34708955 |
Electromyogram abnormal | 12.98 | 11.25 | 7 | 245769 | 54 | 34711101 |
Lichenoid keratosis | 12.97 | 11.25 | 43 | 245733 | 2465 | 34708690 |
Splenic necrosis | 12.88 | 11.25 | 9 | 245767 | 115 | 34711040 |
Vitamin B complex deficiency | 12.86 | 11.25 | 15 | 245761 | 387 | 34710768 |
Blood bilirubin abnormal | 12.84 | 11.25 | 21 | 245755 | 751 | 34710404 |
Myocarditis | 12.84 | 11.25 | 51 | 245725 | 13631 | 34697524 |
Adrenal cyst | 12.81 | 11.25 | 10 | 245766 | 153 | 34711002 |
Staphylococcal bacteraemia | 12.78 | 11.25 | 25 | 245751 | 8427 | 34702728 |
Skin toxicity | 12.77 | 11.25 | 9 | 245767 | 4775 | 34706380 |
AST/ALT ratio abnormal | 12.76 | 11.25 | 5 | 245771 | 16 | 34711139 |
Myoglobinaemia | 12.75 | 11.25 | 9 | 245767 | 117 | 34711038 |
Jaundice cholestatic | 12.74 | 11.25 | 67 | 245709 | 4727 | 34706428 |
Blood pressure diastolic increased | 12.71 | 11.25 | 10 | 245766 | 5015 | 34706140 |
Colorectal cancer | 12.65 | 11.25 | 9 | 245767 | 4752 | 34706403 |
Barrett's oesophagus | 12.62 | 11.25 | 16 | 245760 | 451 | 34710704 |
Systemic infection | 12.61 | 11.25 | 71 | 245705 | 5141 | 34706014 |
Body temperature decreased | 12.60 | 11.25 | 48 | 245728 | 12986 | 34698169 |
Uveitis | 12.55 | 11.25 | 21 | 245755 | 7514 | 34703641 |
Macroenzyme creatine kinase | 12.53 | 11.25 | 5 | 245771 | 17 | 34711138 |
Product packaging quantity issue | 12.49 | 11.25 | 23 | 245753 | 906 | 34710249 |
Cerebral arteriosclerosis | 12.48 | 11.25 | 17 | 245759 | 515 | 34710640 |
Apparent death | 12.45 | 11.25 | 5 | 245771 | 3639 | 34707516 |
SARS-CoV-2 test positive | 12.43 | 11.25 | 14 | 245762 | 5919 | 34705236 |
Hyperlactacidaemia | 12.42 | 11.25 | 48 | 245728 | 2968 | 34708187 |
Overflow diarrhoea | 12.37 | 11.25 | 6 | 245770 | 36 | 34711119 |
Coronary angioplasty | 12.33 | 11.25 | 15 | 245761 | 405 | 34710750 |
Upper respiratory tract infection | 12.32 | 11.25 | 161 | 245615 | 32898 | 34678257 |
Product storage error | 12.30 | 11.25 | 24 | 245752 | 8098 | 34703057 |
Dental examination abnormal | 12.24 | 11.25 | 4 | 245772 | 6 | 34711149 |
Blood creatine phosphokinase MB increased | 12.23 | 11.25 | 35 | 245741 | 1851 | 34709304 |
Device leakage | 12.22 | 11.25 | 17 | 245759 | 6558 | 34704597 |
Dry mouth | 12.22 | 11.25 | 288 | 245488 | 29877 | 34681278 |
Erythema | 12.21 | 11.25 | 505 | 245271 | 88275 | 34622880 |
Antipsychotic drug level decreased | 12.21 | 11.25 | 24 | 245752 | 993 | 34710162 |
Erosive duodenitis | 12.17 | 11.25 | 33 | 245743 | 1691 | 34709464 |
Epiglottitis | 12.16 | 11.25 | 15 | 245761 | 411 | 34710744 |
Anuria | 12.15 | 11.25 | 119 | 245657 | 10266 | 34700889 |
Haemoglobin urine present | 12.14 | 11.25 | 9 | 245767 | 127 | 34711028 |
Iron binding capacity total increased | 12.10 | 11.25 | 6 | 245770 | 38 | 34711117 |
Glycogen storage disease type V | 12.10 | 11.25 | 6 | 245770 | 38 | 34711117 |
Diabetic neuropathy | 12.09 | 11.25 | 60 | 245716 | 4137 | 34707018 |
Coronary artery thrombosis | 12.05 | 11.25 | 38 | 245738 | 2121 | 34709034 |
Staphylococcal infection | 12.05 | 11.25 | 160 | 245616 | 32600 | 34678555 |
Liver function test increased | 12.01 | 11.25 | 57 | 245719 | 14508 | 34696647 |
Immature granulocyte count increased | 11.90 | 11.25 | 9 | 245767 | 131 | 34711024 |
Musculoskeletal stiffness | 11.88 | 11.25 | 244 | 245532 | 46436 | 34664719 |
Parkinson's disease | 11.86 | 11.25 | 29 | 245747 | 1395 | 34709760 |
Dyspnoea exertional | 11.85 | 11.25 | 393 | 245383 | 42886 | 34668269 |
Tendon operation | 11.85 | 11.25 | 6 | 245770 | 40 | 34711115 |
Subacute hepatic failure | 11.80 | 11.25 | 8 | 245768 | 97 | 34711058 |
Psychological trauma | 11.79 | 11.25 | 11 | 245765 | 217 | 34710938 |
Tachypnoea | 11.78 | 11.25 | 78 | 245698 | 18274 | 34692881 |
Faeces discoloured | 11.77 | 11.25 | 158 | 245618 | 14720 | 34696435 |
Gastric cancer | 11.75 | 11.25 | 17 | 245759 | 6452 | 34704703 |
Headache | 11.75 | 11.25 | 1233 | 244543 | 199402 | 34511753 |
Respiratory fatigue | 11.73 | 11.25 | 8 | 245768 | 98 | 34711057 |
Crush syndrome | 11.72 | 11.25 | 7 | 245769 | 67 | 34711088 |
Hyperventilation | 11.68 | 11.25 | 45 | 245731 | 2779 | 34708376 |
Forced expiratory volume decreased | 11.61 | 11.25 | 4 | 245772 | 3199 | 34707956 |
Pancreatic duct stenosis | 11.60 | 11.25 | 10 | 245766 | 177 | 34710978 |
Butterfly rash | 11.60 | 11.25 | 8 | 245768 | 100 | 34711055 |
Rhinovirus infection | 11.59 | 11.25 | 8 | 245768 | 4291 | 34706864 |
Impaired work ability | 11.59 | 11.25 | 86 | 245690 | 6844 | 34704311 |
Neonatal respiratory distress syndrome | 11.57 | 11.25 | 7 | 245769 | 4027 | 34707128 |
Breast tenderness | 11.53 | 11.25 | 20 | 245756 | 751 | 34710404 |
Blood lactate dehydrogenase | 11.52 | 11.25 | 4 | 245772 | 8 | 34711147 |
Carnitine palmitoyltransferase deficiency | 11.52 | 11.25 | 4 | 245772 | 8 | 34711147 |
Toxic epidermal necrolysis | 11.51 | 11.25 | 97 | 245679 | 21549 | 34689606 |
Mixed liver injury | 11.48 | 11.25 | 3 | 245773 | 2870 | 34708285 |
Pseudoaldosteronism | 11.46 | 11.25 | 7 | 245769 | 70 | 34711085 |
Vertebral artery stenosis | 11.46 | 11.25 | 9 | 245767 | 139 | 34711016 |
COVID-19 pneumonia | 11.46 | 11.25 | 71 | 245705 | 16896 | 34694259 |
Fistula | 11.45 | 11.25 | 19 | 245757 | 6821 | 34704334 |
Venoocclusive disease | 11.44 | 11.25 | 3 | 245773 | 2864 | 34708291 |
Epiglottic oedema | 11.42 | 11.25 | 10 | 245766 | 181 | 34710974 |
Osteoma | 11.40 | 11.25 | 8 | 245768 | 103 | 34711052 |
Myotonia | 11.38 | 11.25 | 6 | 245770 | 44 | 34711111 |
Renal impairment | 11.37 | 11.25 | 791 | 244985 | 93722 | 34617433 |
Tongue dry | 11.31 | 11.25 | 11 | 245765 | 229 | 34710926 |
Hepatitis cholestatic | 11.30 | 11.25 | 95 | 245681 | 7852 | 34703303 |
Retinal vascular thrombosis | 11.29 | 11.25 | 7 | 245769 | 72 | 34711083 |
Volvulus | 11.29 | 11.25 | 31 | 245745 | 1601 | 34709554 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Rhabdomyolysis | 4513.14 | 9.72 | 3922 | 400971 | 99209 | 79240286 |
Myalgia | 1831.37 | 9.72 | 3337 | 401556 | 182304 | 79157191 |
Drug interaction | 1346.52 | 9.72 | 4895 | 399998 | 410288 | 78929207 |
Blood creatine phosphokinase increased | 1285.47 | 9.72 | 1631 | 403262 | 64459 | 79275036 |
Drug ineffective | 1169.30 | 9.72 | 2336 | 402557 | 1078577 | 78260918 |
Myopathy | 1012.40 | 9.72 | 838 | 404055 | 19725 | 79319770 |
Acute kidney injury | 977.23 | 9.72 | 5202 | 399691 | 514202 | 78825293 |
Off label use | 938.65 | 9.72 | 2009 | 402884 | 905206 | 78434289 |
Myocardial infarction | 700.52 | 9.72 | 2292 | 402601 | 181837 | 79157658 |
Maternal exposure during pregnancy | 514.94 | 9.72 | 49 | 404844 | 136489 | 79203006 |
Treatment failure | 509.20 | 9.72 | 120 | 404773 | 170366 | 79169129 |
Synovitis | 503.00 | 9.72 | 81 | 404812 | 150653 | 79188842 |
Coronary artery disease | 480.35 | 9.72 | 1041 | 403852 | 64433 | 79275062 |
Infusion related reaction | 457.83 | 9.72 | 303 | 404590 | 229934 | 79109561 |
Hand deformity | 452.56 | 9.72 | 17 | 404876 | 103902 | 79235593 |
Systemic lupus erythematosus | 425.31 | 9.72 | 56 | 404837 | 121093 | 79218402 |
Anti-cyclic citrullinated peptide antibody positive | 404.53 | 9.72 | 3 | 404890 | 83140 | 79256355 |
Myositis | 402.77 | 9.72 | 492 | 404401 | 18676 | 79320819 |
Pemphigus | 385.57 | 9.72 | 32 | 404861 | 99550 | 79239945 |
Rheumatoid arthritis | 369.72 | 9.72 | 309 | 404584 | 208161 | 79131334 |
Drug abuse | 366.24 | 9.72 | 184 | 404709 | 162507 | 79176988 |
Syncope | 364.01 | 9.72 | 1838 | 403055 | 177611 | 79161884 |
Cerebrovascular accident | 348.96 | 9.72 | 1638 | 403255 | 153654 | 79185841 |
Immune-mediated myositis | 348.23 | 9.72 | 218 | 404675 | 3249 | 79336246 |
Joint swelling | 341.52 | 9.72 | 588 | 404305 | 288058 | 79051437 |
Product use in unapproved indication | 337.33 | 9.72 | 467 | 404426 | 249892 | 79089603 |
Muscular weakness | 337.09 | 9.72 | 1662 | 403231 | 159067 | 79180428 |
Product use issue | 324.16 | 9.72 | 352 | 404541 | 209470 | 79130025 |
Fall | 319.51 | 9.72 | 3831 | 401062 | 483798 | 78855697 |
Nasopharyngitis | 319.15 | 9.72 | 497 | 404396 | 253384 | 79086111 |
Drug intolerance | 318.91 | 9.72 | 531 | 404362 | 263588 | 79075907 |
Exposure during pregnancy | 312.33 | 9.72 | 66 | 404827 | 101066 | 79238429 |
Therapeutic product effect decreased | 310.60 | 9.72 | 227 | 404666 | 163636 | 79175859 |
Glossodynia | 304.03 | 9.72 | 75 | 404818 | 103262 | 79236233 |
Febrile neutropenia | 300.18 | 9.72 | 442 | 404451 | 230557 | 79108938 |
Tendon rupture | 279.02 | 9.72 | 326 | 404567 | 11800 | 79327695 |
Product prescribing error | 275.98 | 9.72 | 665 | 404228 | 44148 | 79295347 |
Dizziness | 268.77 | 9.72 | 3953 | 400940 | 522488 | 78817007 |
International normalised ratio increased | 254.17 | 9.72 | 976 | 403917 | 83745 | 79255750 |
Arthropathy | 251.11 | 9.72 | 318 | 404575 | 176793 | 79162702 |
Hyponatraemia | 250.14 | 9.72 | 1653 | 403240 | 176195 | 79163300 |
Transient ischaemic attack | 246.82 | 9.72 | 706 | 404187 | 51989 | 79287506 |
Toxicity to various agents | 233.35 | 9.72 | 1224 | 403669 | 420316 | 78919179 |
Gastrointestinal haemorrhage | 231.88 | 9.72 | 1412 | 403481 | 146307 | 79193188 |
Duodenal ulcer perforation | 231.40 | 9.72 | 31 | 404862 | 66180 | 79273315 |
Helicobacter infection | 218.30 | 9.72 | 44 | 404849 | 69660 | 79269835 |
Lactic acidosis | 214.70 | 9.72 | 815 | 404078 | 69544 | 79269951 |
Folliculitis | 213.80 | 9.72 | 18 | 404875 | 55362 | 79284133 |
C-reactive protein abnormal | 213.74 | 9.72 | 7 | 404886 | 48360 | 79291135 |
Atrial fibrillation | 210.58 | 9.72 | 1721 | 403172 | 196165 | 79143330 |
Asthenia | 209.56 | 9.72 | 3705 | 401188 | 507984 | 78831511 |
Hyperkalaemia | 204.56 | 9.72 | 1132 | 403761 | 113266 | 79226229 |
Angioedema | 204.03 | 9.72 | 846 | 404047 | 75189 | 79264306 |
Hypoglycaemia | 204.01 | 9.72 | 1038 | 403855 | 100556 | 79238939 |
Renal failure | 202.23 | 9.72 | 1726 | 403167 | 199242 | 79140253 |
Acute myocardial infarction | 199.59 | 9.72 | 848 | 404045 | 76188 | 79263307 |
Liver function test abnormal | 197.68 | 9.72 | 748 | 404145 | 63727 | 79275768 |
Sleep disorder due to general medical condition, insomnia type | 197.26 | 9.72 | 5 | 404888 | 43551 | 79295944 |
Cardiac failure congestive | 196.22 | 9.72 | 1317 | 403576 | 141085 | 79198410 |
Therapeutic product effect incomplete | 190.87 | 9.72 | 264 | 404629 | 141381 | 79198114 |
Discomfort | 190.33 | 9.72 | 214 | 404679 | 125403 | 79214092 |
Infection | 189.90 | 9.72 | 612 | 404281 | 241100 | 79098395 |
Rheumatoid factor positive | 184.85 | 9.72 | 39 | 404854 | 59800 | 79279695 |
Alopecia | 184.39 | 9.72 | 582 | 404311 | 230773 | 79108722 |
Condition aggravated | 177.71 | 9.72 | 1657 | 403236 | 499467 | 78840028 |
Stomatitis | 176.12 | 9.72 | 296 | 404597 | 146461 | 79193034 |
Intentional product use issue | 174.19 | 9.72 | 316 | 404577 | 151796 | 79187699 |
General physical health deterioration | 173.53 | 9.72 | 2148 | 402745 | 273090 | 79066405 |
Sinusitis | 172.34 | 9.72 | 469 | 404424 | 195032 | 79144463 |
Contraindicated product administered | 171.85 | 9.72 | 337 | 404556 | 157201 | 79182294 |
Hypersensitivity | 171.77 | 9.72 | 716 | 404177 | 261523 | 79077972 |
Product monitoring error | 167.03 | 9.72 | 216 | 404677 | 8690 | 79330805 |
Angina pectoris | 165.95 | 9.72 | 609 | 404284 | 51123 | 79288372 |
Swelling | 165.17 | 9.72 | 556 | 404337 | 216155 | 79123340 |
Pyrexia | 156.39 | 9.72 | 2465 | 402428 | 676244 | 78663251 |
Dehydration | 154.31 | 9.72 | 1932 | 402961 | 246255 | 79093240 |
Chromaturia | 153.10 | 9.72 | 377 | 404516 | 25369 | 79314126 |
Labelled drug-drug interaction medication error | 149.96 | 9.72 | 391 | 404502 | 27259 | 79312236 |
Psoriatic arthropathy | 149.11 | 9.72 | 107 | 404786 | 77892 | 79261603 |
Wound | 145.32 | 9.72 | 228 | 404665 | 115951 | 79223544 |
Bradycardia | 142.00 | 9.72 | 1175 | 403718 | 134382 | 79205113 |
Confusional state | 140.95 | 9.72 | 2333 | 402560 | 315664 | 79023831 |
Neutropenia | 140.36 | 9.72 | 870 | 404023 | 286840 | 79052655 |
Chest pain | 139.40 | 9.72 | 2109 | 402784 | 280195 | 79059300 |
Pericarditis | 138.69 | 9.72 | 196 | 404697 | 104040 | 79235455 |
Irritable bowel syndrome | 131.79 | 9.72 | 76 | 404817 | 62165 | 79277330 |
Lip swelling | 131.54 | 9.72 | 482 | 404411 | 40429 | 79299066 |
Completed suicide | 127.35 | 9.72 | 729 | 404164 | 245038 | 79094457 |
Drug resistance | 123.43 | 9.72 | 31 | 404862 | 42182 | 79297313 |
Fibromyalgia | 123.33 | 9.72 | 88 | 404805 | 64252 | 79275243 |
Cardiospasm | 123.25 | 9.72 | 115 | 404778 | 3186 | 79336309 |
Nightmare | 122.55 | 9.72 | 348 | 404545 | 25513 | 79313982 |
Sleep terror | 121.65 | 9.72 | 131 | 404762 | 4327 | 79335168 |
Carotid artery occlusion | 118.41 | 9.72 | 169 | 404724 | 7478 | 79332017 |
Amnesia | 118.08 | 9.72 | 632 | 404261 | 62425 | 79277070 |
Malignant neoplasm progression | 117 | 9.72 | 330 | 404563 | 135660 | 79203835 |
Muscle atrophy | 116.91 | 9.72 | 207 | 404686 | 11025 | 79328470 |
Blood glucose increased | 115.83 | 9.72 | 988 | 403905 | 113987 | 79225508 |
Myocardial ischaemia | 115.71 | 9.72 | 338 | 404555 | 25181 | 79314314 |
Palmoplantar keratoderma | 113.55 | 9.72 | 116 | 404777 | 3600 | 79335895 |
Muscle rupture | 111.46 | 9.72 | 115 | 404778 | 3612 | 79335883 |
Pain | 109.34 | 9.72 | 2730 | 402163 | 701072 | 78638423 |
Muscle injury | 109.09 | 9.72 | 55 | 404838 | 48506 | 79290989 |
Circulatory collapse | 107.28 | 9.72 | 427 | 404466 | 37241 | 79302254 |
Abdominal discomfort | 106.87 | 9.72 | 789 | 404104 | 249938 | 79089557 |
Hepatic enzyme increased | 106.08 | 9.72 | 521 | 404372 | 182089 | 79157406 |
Haematuria | 106.04 | 9.72 | 655 | 404238 | 68181 | 79271314 |
Pruritus genital | 105.54 | 9.72 | 122 | 404771 | 4364 | 79335131 |
Cytomegalovirus infection | 104.05 | 9.72 | 43 | 404850 | 42601 | 79296894 |
Device expulsion | 103.80 | 9.72 | 7 | 404886 | 25854 | 79313641 |
Muscle spasms | 103.78 | 9.72 | 1349 | 403544 | 173381 | 79166114 |
Cardiovascular disorder | 103.03 | 9.72 | 260 | 404633 | 17765 | 79321730 |
Weight increased | 101.69 | 9.72 | 909 | 403984 | 276477 | 79063018 |
Subarachnoid haemorrhage | 101.45 | 9.72 | 314 | 404579 | 24151 | 79315344 |
Injection site pain | 101.01 | 9.72 | 330 | 404563 | 129508 | 79209987 |
Rash | 100.18 | 9.72 | 2206 | 402687 | 576152 | 78763343 |
Dyspnoea | 100.13 | 9.72 | 5312 | 399581 | 851713 | 78487782 |
Coronary artery stenosis | 99.03 | 9.72 | 205 | 404688 | 12279 | 79327216 |
Ill-defined disorder | 98.91 | 9.72 | 113 | 404780 | 65762 | 79273733 |
Gait disturbance | 98.82 | 9.72 | 1541 | 403352 | 205965 | 79133530 |
Abortion spontaneous | 98.05 | 9.72 | 16 | 404877 | 29491 | 79310004 |
Blood creatinine increased | 97.98 | 9.72 | 1211 | 403682 | 153846 | 79185649 |
Angina unstable | 97.20 | 9.72 | 241 | 404652 | 16286 | 79323209 |
Arteriosclerosis coronary artery | 96.67 | 9.72 | 252 | 404641 | 17564 | 79321931 |
Musculoskeletal stiffness | 96.16 | 9.72 | 509 | 404384 | 174499 | 79164996 |
Haematemesis | 95.94 | 9.72 | 521 | 404372 | 51743 | 79287752 |
Myelosuppression | 94.56 | 9.72 | 43 | 404850 | 40253 | 79299242 |
Self esteem decreased | 93.14 | 9.72 | 60 | 404833 | 942 | 79338553 |
Drug ineffective for unapproved indication | 91.91 | 9.72 | 75 | 404818 | 51163 | 79288332 |
Renal impairment | 90.70 | 9.72 | 1211 | 403682 | 156572 | 79182923 |
Necrotising myositis | 89.43 | 9.72 | 64 | 404829 | 1204 | 79338291 |
Cerebral haemorrhage | 88.96 | 9.72 | 549 | 404344 | 57124 | 79282371 |
Melaena | 88.57 | 9.72 | 571 | 404322 | 60319 | 79279176 |
Tension headache | 88.46 | 9.72 | 143 | 404750 | 7068 | 79332427 |
Idiopathic pulmonary fibrosis | 87.96 | 9.72 | 108 | 404785 | 4120 | 79335375 |
Haematochezia | 87.66 | 9.72 | 752 | 404141 | 86893 | 79252602 |
Gastrointestinal disorder | 86.72 | 9.72 | 323 | 404570 | 121882 | 79217613 |
Arthralgia | 86.28 | 9.72 | 2227 | 402666 | 569576 | 78769919 |
Pregnancy | 86.07 | 9.72 | 16 | 404877 | 26835 | 79312660 |
Lethargy | 85.82 | 9.72 | 706 | 404187 | 80586 | 79258909 |
Coronary artery occlusion | 82.46 | 9.72 | 216 | 404677 | 15099 | 79324396 |
Immunisation | 81.89 | 9.72 | 76 | 404817 | 2091 | 79337404 |
Atrial tachycardia | 81.50 | 9.72 | 137 | 404756 | 6996 | 79332499 |
Inappropriate schedule of product administration | 81.25 | 9.72 | 375 | 404518 | 133253 | 79206242 |
Hip arthroplasty | 81.07 | 9.72 | 40 | 404853 | 35716 | 79303779 |
Myoglobinuria | 81.00 | 9.72 | 57 | 404836 | 1043 | 79338452 |
Anosmia | 79.48 | 9.72 | 153 | 404740 | 8691 | 79330804 |
Erectile dysfunction | 79.14 | 9.72 | 207 | 404686 | 14457 | 79325038 |
Appendicolith | 78.16 | 9.72 | 149 | 404744 | 8402 | 79331093 |
Blister | 77.65 | 9.72 | 327 | 404566 | 119149 | 79220346 |
Muscle necrosis | 77.17 | 9.72 | 62 | 404831 | 1396 | 79338099 |
Upper gastrointestinal haemorrhage | 76.28 | 9.72 | 413 | 404480 | 40967 | 79298528 |
Ischaemic stroke | 76.17 | 9.72 | 352 | 404541 | 32779 | 79306716 |
Ventricular tachycardia | 75.60 | 9.72 | 416 | 404477 | 41519 | 79297976 |
Myoglobin blood increased | 74.64 | 9.72 | 86 | 404807 | 3065 | 79336430 |
Therapy non-responder | 74.31 | 9.72 | 231 | 404662 | 92074 | 79247421 |
COVID-19 | 74.14 | 9.72 | 482 | 404411 | 157192 | 79182303 |
Oedema peripheral | 73.83 | 9.72 | 1739 | 403154 | 250549 | 79088946 |
Pancreatitis acute | 72.65 | 9.72 | 466 | 404427 | 49138 | 79290357 |
Product dose omission issue | 72.65 | 9.72 | 855 | 404038 | 246682 | 79092813 |
Hospitalisation | 72.26 | 9.72 | 241 | 404652 | 93995 | 79245500 |
Polymyositis | 72.15 | 9.72 | 83 | 404810 | 2953 | 79336542 |
Asthma | 71.94 | 9.72 | 397 | 404496 | 134698 | 79204797 |
Amyotrophic lateral sclerosis | 71.20 | 9.72 | 65 | 404828 | 1750 | 79337745 |
Bone erosion | 71.14 | 9.72 | 5 | 404888 | 17842 | 79321653 |
Lower respiratory tract infection | 70.31 | 9.72 | 377 | 404516 | 128843 | 79210652 |
Blood pressure fluctuation | 70.31 | 9.72 | 147 | 404746 | 66998 | 79272497 |
Drug dependence | 70.28 | 9.72 | 62 | 404831 | 40707 | 79298788 |
Muscle twitching | 69.93 | 9.72 | 280 | 404613 | 24484 | 79315011 |
Haemorrhage intracranial | 69.89 | 9.72 | 291 | 404602 | 25902 | 79313593 |
Subdural haematoma | 69.35 | 9.72 | 330 | 404563 | 31104 | 79308391 |
Palpitations | 69.17 | 9.72 | 963 | 403930 | 125647 | 79213848 |
Mucosal inflammation | 69.06 | 9.72 | 178 | 404715 | 75402 | 79264093 |
Abnormal dreams | 68.79 | 9.72 | 168 | 404725 | 11244 | 79328251 |
Swollen tongue | 68.68 | 9.72 | 410 | 404483 | 42160 | 79297335 |
Pancreatitis necrotising | 67.45 | 9.72 | 91 | 404802 | 3817 | 79335678 |
Acute coronary syndrome | 67.10 | 9.72 | 248 | 404645 | 20885 | 79318610 |
Haemodialysis | 67.00 | 9.72 | 224 | 404669 | 17944 | 79321551 |
Diabetes mellitus inadequate control | 66.65 | 9.72 | 272 | 404621 | 23992 | 79315503 |
Ischaemic cardiomyopathy | 66.57 | 9.72 | 131 | 404762 | 7564 | 79331931 |
Social problem | 65.39 | 9.72 | 56 | 404837 | 1382 | 79338113 |
Balance disorder | 64.99 | 9.72 | 778 | 404115 | 98079 | 79241416 |
Sinus bradycardia | 64.65 | 9.72 | 277 | 404616 | 24970 | 79314525 |
Hypotension | 64.26 | 9.72 | 2791 | 402102 | 437526 | 78901969 |
Intentional overdose | 64.02 | 9.72 | 298 | 404595 | 105662 | 79233833 |
Sedation complication | 63.60 | 9.72 | 4 | 404889 | 15665 | 79323830 |
Therapy partial responder | 63.59 | 9.72 | 7 | 404886 | 17390 | 79322105 |
Graft versus host disease | 63.59 | 9.72 | 3 | 404890 | 15023 | 79324472 |
Oxygen saturation decreased | 63.49 | 9.72 | 389 | 404504 | 128658 | 79210837 |
Quality of life decreased | 63.46 | 9.72 | 154 | 404739 | 10266 | 79329229 |
Chronic obstructive pulmonary disease | 62.78 | 9.72 | 687 | 404206 | 84732 | 79254763 |
Death | 62.47 | 9.72 | 2300 | 402593 | 564214 | 78775281 |
Bronchopulmonary aspergillosis | 62.11 | 9.72 | 18 | 404875 | 22276 | 79317219 |
Illness | 60.33 | 9.72 | 89 | 404804 | 46422 | 79293073 |
Subdural haemorrhage | 59.83 | 9.72 | 108 | 404785 | 5840 | 79333655 |
Influenza | 59.51 | 9.72 | 399 | 404494 | 129207 | 79210288 |
High density lipoprotein decreased | 59.41 | 9.72 | 94 | 404799 | 4561 | 79334934 |
Mitral valve incompetence | 58.80 | 9.72 | 294 | 404599 | 28271 | 79311224 |
Haemophagocytic lymphohistiocytosis | 58.37 | 9.72 | 19 | 404874 | 21818 | 79317677 |
Blood urea increased | 57.69 | 9.72 | 435 | 404458 | 48355 | 79291140 |
Transplant rejection | 57.36 | 9.72 | 14 | 404879 | 19423 | 79320072 |
Disease progression | 57.12 | 9.72 | 629 | 404264 | 183733 | 79155762 |
Septic shock | 56.91 | 9.72 | 377 | 404516 | 122424 | 79217071 |
Pneumonia | 56.74 | 9.72 | 2757 | 402136 | 657489 | 78682006 |
Pneumocystis jirovecii pneumonia | 56.56 | 9.72 | 49 | 404844 | 32459 | 79307036 |
Peripheral swelling | 56.02 | 9.72 | 997 | 403896 | 268620 | 79070875 |
Arteriosclerosis | 55.46 | 9.72 | 211 | 404682 | 18016 | 79321479 |
Poisoning deliberate | 54.71 | 9.72 | 14 | 404879 | 18814 | 79320681 |
Injection site erythema | 54.61 | 9.72 | 208 | 404685 | 77989 | 79261506 |
Myopathy toxic | 54.55 | 9.72 | 45 | 404848 | 1053 | 79338442 |
Facial pain | 54.48 | 9.72 | 162 | 404731 | 12188 | 79327307 |
Live birth | 54.35 | 9.72 | 14 | 404879 | 18730 | 79320765 |
Hyperhidrosis | 54.15 | 9.72 | 1075 | 403818 | 150417 | 79189078 |
Therapeutic response shortened | 54.07 | 9.72 | 8 | 404885 | 15855 | 79323640 |
Knee arthroplasty | 53.94 | 9.72 | 85 | 404808 | 43163 | 79296332 |
Grip strength decreased | 53.43 | 9.72 | 22 | 404871 | 21847 | 79317648 |
Neutrophil count decreased | 52.86 | 9.72 | 271 | 404622 | 93688 | 79245807 |
Haematoma | 52.79 | 9.72 | 449 | 404444 | 51746 | 79287749 |
Diplopia | 52.51 | 9.72 | 320 | 404573 | 33146 | 79306349 |
Naevus flammeus | 52.49 | 9.72 | 19 | 404874 | 70 | 79339425 |
Bone marrow failure | 51.75 | 9.72 | 114 | 404779 | 50993 | 79288502 |
Neoplasm progression | 51.74 | 9.72 | 116 | 404777 | 51566 | 79287929 |
Actinic keratosis | 51.23 | 9.72 | 102 | 404791 | 5940 | 79333555 |
Arthritis | 50.60 | 9.72 | 358 | 404535 | 114522 | 79224973 |
Rhinorrhoea | 50.17 | 9.72 | 207 | 404686 | 75867 | 79263628 |
Blood loss anaemia | 50.15 | 9.72 | 183 | 404710 | 15315 | 79324180 |
Poor venous access | 49.93 | 9.72 | 15 | 404878 | 18134 | 79321361 |
Carotid artery stenosis | 49.71 | 9.72 | 126 | 404767 | 8632 | 79330863 |
Suicide attempt | 49.65 | 9.72 | 234 | 404659 | 82698 | 79256797 |
Lung disorder | 49.59 | 9.72 | 225 | 404668 | 80332 | 79259163 |
Injection site reaction | 49.30 | 9.72 | 130 | 404763 | 54655 | 79284840 |
Urosepsis | 49.21 | 9.72 | 265 | 404628 | 26230 | 79313265 |
Therapeutic response decreased | 49.20 | 9.72 | 174 | 404719 | 66679 | 79272816 |
Premature delivery | 49.18 | 9.72 | 29 | 404864 | 23438 | 79316057 |
Hyperglycaemia | 49.10 | 9.72 | 560 | 404333 | 69775 | 79269720 |
Renal injury | 49.09 | 9.72 | 193 | 404700 | 16734 | 79322761 |
Blindness | 48.79 | 9.72 | 278 | 404615 | 28105 | 79311390 |
Disturbance in attention | 48.76 | 9.72 | 432 | 404461 | 50369 | 79289126 |
Venoocclusive liver disease | 47.79 | 9.72 | 3 | 404890 | 11768 | 79327727 |
Agranulocytosis | 47.63 | 9.72 | 98 | 404795 | 44932 | 79294563 |
Cytokine release syndrome | 47.56 | 9.72 | 68 | 404825 | 35930 | 79303565 |
Blood pressure systolic increased | 47.54 | 9.72 | 177 | 404716 | 66809 | 79272686 |
Pancreatitis | 47.42 | 9.72 | 545 | 404348 | 68030 | 79271465 |
Drug reaction with eosinophilia and systemic symptoms | 47.42 | 9.72 | 167 | 404726 | 64077 | 79275418 |
Loss of consciousness | 47.38 | 9.72 | 1152 | 403741 | 166791 | 79172704 |
Pancytopenia | 47.25 | 9.72 | 576 | 404317 | 165169 | 79174326 |
Diabetic ketoacidosis | 47.19 | 9.72 | 316 | 404577 | 33806 | 79305689 |
Drug hypersensitivity | 47.17 | 9.72 | 1156 | 403737 | 297760 | 79041735 |
Pathogen resistance | 47.16 | 9.72 | 8 | 404885 | 14334 | 79325161 |
Coma | 47.13 | 9.72 | 308 | 404585 | 100341 | 79239154 |
Sedation | 46.81 | 9.72 | 123 | 404770 | 51772 | 79287723 |
Mitochondrial myopathy | 46.71 | 9.72 | 25 | 404868 | 272 | 79339223 |
Haematotoxicity | 46.14 | 9.72 | 11 | 404882 | 15508 | 79323987 |
Caesarean section | 45.93 | 9.72 | 5 | 404888 | 12530 | 79326965 |
Accidental exposure to product | 45.65 | 9.72 | 55 | 404838 | 31267 | 79308228 |
Faeces pale | 45.39 | 9.72 | 65 | 404828 | 2885 | 79336610 |
Pain in extremity | 45.27 | 9.72 | 2274 | 402619 | 362264 | 78977231 |
Impaired healing | 44.81 | 9.72 | 261 | 404632 | 87394 | 79252101 |
White blood cell count decreased | 44.79 | 9.72 | 679 | 404214 | 187609 | 79151886 |
Orthostatic intolerance | 44.72 | 9.72 | 52 | 404841 | 1872 | 79337623 |
Therapeutic drug monitoring analysis not performed | 44.46 | 9.72 | 52 | 404841 | 1884 | 79337611 |
Aspergillus infection | 44.10 | 9.72 | 21 | 404872 | 19140 | 79320355 |
Hyperlipidaemia | 43.82 | 9.72 | 254 | 404639 | 25839 | 79313656 |
Duodenal ulcer | 43.78 | 9.72 | 182 | 404711 | 16187 | 79323308 |
Injection site bruising | 43.57 | 9.72 | 89 | 404804 | 40913 | 79298582 |
Epstein-Barr virus infection | 43.30 | 9.72 | 10 | 404883 | 14406 | 79325089 |
Hypertensive crisis | 42.91 | 9.72 | 214 | 404679 | 20556 | 79318939 |
Deep vein thrombosis postoperative | 42.89 | 9.72 | 3 | 404890 | 10749 | 79328746 |
Headache | 42.77 | 9.72 | 2803 | 402090 | 650969 | 78688526 |
Urticaria | 41.98 | 9.72 | 674 | 404219 | 184527 | 79154968 |
Ventricular fibrillation | 41.97 | 9.72 | 292 | 404601 | 31634 | 79307861 |
Blood urea abnormal | 41.60 | 9.72 | 42 | 404851 | 1285 | 79338210 |
Cutaneous T-cell dyscrasia | 41.49 | 9.72 | 15 | 404878 | 55 | 79339440 |
Presyncope | 41.43 | 9.72 | 353 | 404540 | 40701 | 79298794 |
Hallucination | 41.23 | 9.72 | 638 | 404255 | 85107 | 79254388 |
Fear | 40.90 | 9.72 | 220 | 404673 | 21766 | 79317729 |
Contraindicated product prescribed | 40.82 | 9.72 | 47 | 404846 | 1674 | 79337821 |
Sleep disorder due to a general medical condition | 40.75 | 9.72 | 11 | 404882 | 14266 | 79325229 |
Anaemia | 40.63 | 9.72 | 2700 | 402193 | 442315 | 78897180 |
Dermatomyositis | 40.62 | 9.72 | 69 | 404824 | 3554 | 79335941 |
Tumour lysis syndrome | 40.55 | 9.72 | 37 | 404856 | 23902 | 79315593 |
C-reactive protein increased | 40.44 | 9.72 | 439 | 404454 | 128588 | 79210907 |
Urogenital haemorrhage | 40.31 | 9.72 | 36 | 404857 | 941 | 79338554 |
Loss of personal independence in daily activities | 40.29 | 9.72 | 330 | 404563 | 102250 | 79237245 |
Pain of skin | 40.28 | 9.72 | 164 | 404729 | 14449 | 79325046 |
Body temperature decreased | 40.25 | 9.72 | 63 | 404830 | 32082 | 79307413 |
Blood glucose fluctuation | 39.89 | 9.72 | 98 | 404795 | 6584 | 79332911 |
Wheezing | 39.82 | 9.72 | 389 | 404504 | 116275 | 79223220 |
Inflammation | 38.96 | 9.72 | 297 | 404596 | 93456 | 79246039 |
Arrhythmia | 38.86 | 9.72 | 479 | 404414 | 60793 | 79278702 |
Device difficult to use | 38.80 | 9.72 | 10 | 404883 | 13375 | 79326120 |
Psychiatric symptom | 38.67 | 9.72 | 100 | 404793 | 6935 | 79332560 |
Diverticulum | 38.58 | 9.72 | 164 | 404729 | 14732 | 79324763 |
Breast cancer stage III | 38.46 | 9.72 | 3 | 404890 | 9823 | 79329672 |
Lower gastrointestinal haemorrhage | 38.31 | 9.72 | 173 | 404720 | 15952 | 79323543 |
Atrioventricular block | 38.25 | 9.72 | 157 | 404736 | 13884 | 79325611 |
Thrombotic microangiopathy | 38.10 | 9.72 | 28 | 404865 | 20141 | 79319354 |
Abnormal loss of weight | 38.02 | 9.72 | 111 | 404782 | 8265 | 79331230 |
Gouty tophus | 37.98 | 9.72 | 25 | 404868 | 408 | 79339087 |
Facet joint syndrome | 37.84 | 9.72 | 6 | 404887 | 11296 | 79328199 |
Ankylosing spondylitis | 37.60 | 9.72 | 8 | 404885 | 12197 | 79327298 |
Cardiogenic shock | 37.47 | 9.72 | 351 | 404542 | 41563 | 79297932 |
Intermittent claudication | 37.46 | 9.72 | 65 | 404828 | 3406 | 79336089 |
Glycogen storage disease type V | 37.45 | 9.72 | 12 | 404881 | 27 | 79339468 |
Joint range of motion decreased | 37.31 | 9.72 | 70 | 404823 | 33212 | 79306283 |
Quadriparesis | 37.05 | 9.72 | 65 | 404828 | 3436 | 79336059 |
Peripheral vascular disorder | 37.02 | 9.72 | 107 | 404786 | 7923 | 79331572 |
Respiratory tract haemorrhage | 37.01 | 9.72 | 46 | 404847 | 1777 | 79337718 |
Injection site pruritus | 36.79 | 9.72 | 102 | 404791 | 42181 | 79297314 |
Musculoskeletal toxicity | 36.79 | 9.72 | 19 | 404874 | 191 | 79339304 |
Oedema mouth | 36.74 | 9.72 | 60 | 404833 | 2991 | 79336504 |
Adrenal insufficiency | 36.47 | 9.72 | 55 | 404838 | 28432 | 79311063 |
Electrocardiogram abnormal | 36.41 | 9.72 | 175 | 404718 | 16562 | 79322933 |
Hemiparesis | 36.14 | 9.72 | 294 | 404599 | 33439 | 79306056 |
Pallor | 36.03 | 9.72 | 401 | 404492 | 49661 | 79289834 |
Therapy interrupted | 35.94 | 9.72 | 65 | 404828 | 31276 | 79308219 |
Ventricular extrasystoles | 35.87 | 9.72 | 196 | 404697 | 19508 | 79319987 |
Atrioventricular block complete | 35.64 | 9.72 | 173 | 404720 | 16437 | 79323058 |
Atrioventricular block first degree | 35.08 | 9.72 | 141 | 404752 | 12350 | 79327145 |
Device issue | 35.03 | 9.72 | 52 | 404841 | 27056 | 79312439 |
Labile hypertension | 34.85 | 9.72 | 26 | 404867 | 523 | 79338972 |
Tinnitus | 34.64 | 9.72 | 361 | 404532 | 43972 | 79295523 |
Coronary artery thrombosis | 34.62 | 9.72 | 59 | 404834 | 3047 | 79336448 |
Osteoporosis | 34.59 | 9.72 | 149 | 404744 | 53963 | 79285532 |
Transient global amnesia | 34.55 | 9.72 | 33 | 404860 | 942 | 79338553 |
Cytomegalovirus viraemia | 34.54 | 9.72 | 11 | 404882 | 12810 | 79326685 |
Dialysis | 34.52 | 9.72 | 185 | 404708 | 18277 | 79321218 |
Glomerular filtration rate decreased | 34.31 | 9.72 | 215 | 404678 | 22487 | 79317008 |
Peripheral venous disease | 34.28 | 9.72 | 19 | 404874 | 15890 | 79323605 |
Peripheral arterial occlusive disease | 34.25 | 9.72 | 106 | 404787 | 8152 | 79331343 |
Bacteraemia | 34.24 | 9.72 | 72 | 404821 | 32752 | 79306743 |
Mucosal haemorrhage | 34.09 | 9.72 | 53 | 404840 | 2533 | 79336962 |
Blood potassium increased | 34.04 | 9.72 | 260 | 404633 | 29015 | 79310480 |
Systemic infection | 33.99 | 9.72 | 118 | 404775 | 9634 | 79329861 |
Sinus node dysfunction | 33.95 | 9.72 | 101 | 404792 | 7600 | 79331895 |
Cytopenia | 33.94 | 9.72 | 32 | 404861 | 20351 | 79319144 |
Anuria | 33.87 | 9.72 | 202 | 404691 | 20761 | 79318734 |
Faeces discoloured | 33.48 | 9.72 | 258 | 404635 | 28869 | 79310626 |
Cardiac disorder | 33.44 | 9.72 | 494 | 404399 | 65263 | 79274232 |
Muscle disorder | 33.33 | 9.72 | 83 | 404810 | 5624 | 79333871 |
Herpes zoster | 33.20 | 9.72 | 307 | 404586 | 92776 | 79246719 |
Gynaecomastia | 33.17 | 9.72 | 100 | 404793 | 7581 | 79331914 |
Decorticate posture | 33.08 | 9.72 | 21 | 404872 | 321 | 79339174 |
Blood glucose decreased | 32.78 | 9.72 | 237 | 404656 | 25997 | 79313498 |
Nocturia | 32.67 | 9.72 | 147 | 404746 | 13534 | 79325961 |
Orthostatic hypotension | 32.63 | 9.72 | 432 | 404461 | 55732 | 79283763 |
Blood pressure systolic abnormal | 32.51 | 9.72 | 24 | 404869 | 17223 | 79322272 |
Multiple injuries | 32.07 | 9.72 | 61 | 404832 | 3434 | 79336061 |
Glycosylated haemoglobin increased | 32.03 | 9.72 | 187 | 404706 | 19073 | 79320422 |
Upper respiratory tract infection | 31.95 | 9.72 | 302 | 404591 | 90866 | 79248629 |
Ear pain | 31.91 | 9.72 | 75 | 404818 | 32794 | 79306701 |
Pemphigoid | 31.79 | 9.72 | 158 | 404735 | 15157 | 79324338 |
Collagen disorder | 31.75 | 9.72 | 19 | 404874 | 260 | 79339235 |
Thrombocytopenia | 31.65 | 9.72 | 1066 | 403827 | 264193 | 79075302 |
Acne | 31.53 | 9.72 | 56 | 404837 | 27134 | 79312361 |
Appendicitis | 31.47 | 9.72 | 197 | 404696 | 20597 | 79318898 |
Lichenoid keratosis | 31.45 | 9.72 | 66 | 404827 | 3991 | 79335504 |
Myocardial depression | 31.25 | 9.72 | 24 | 404869 | 505 | 79338990 |
Blood pressure inadequately controlled | 31.11 | 9.72 | 85 | 404808 | 6092 | 79333403 |
Potentiating drug interaction | 30.99 | 9.72 | 107 | 404786 | 8712 | 79330783 |
Immunodeficiency | 30.91 | 9.72 | 39 | 404854 | 21729 | 79317766 |
Jaundice | 30.85 | 9.72 | 410 | 404483 | 52939 | 79286556 |
Compartment syndrome | 30.83 | 9.72 | 75 | 404818 | 5007 | 79334488 |
Infusion site pain | 30.45 | 9.72 | 17 | 404876 | 14159 | 79325336 |
Hyperthermia | 30.41 | 9.72 | 28 | 404865 | 18009 | 79321486 |
Substance abuse | 30.25 | 9.72 | 8 | 404885 | 10518 | 79328977 |
Social avoidant behaviour | 30.23 | 9.72 | 72 | 404821 | 4742 | 79334753 |
Pseudomonas infection | 30.15 | 9.72 | 37 | 404856 | 20866 | 79318629 |
Heavy menstrual bleeding | 29.81 | 9.72 | 17 | 404876 | 13994 | 79325501 |
Low density lipoprotein increased | 29.77 | 9.72 | 104 | 404789 | 8518 | 79330977 |
Disease recurrence | 29.72 | 9.72 | 119 | 404774 | 43990 | 79295505 |
Haemorrhagic stroke | 29.69 | 9.72 | 123 | 404770 | 10923 | 79328572 |
Prostate cancer recurrent | 29.59 | 9.72 | 28 | 404865 | 790 | 79338705 |
Aortic arteriosclerosis | 29.45 | 9.72 | 106 | 404787 | 8812 | 79330683 |
Hypophagia | 29.35 | 9.72 | 356 | 404537 | 45011 | 79294484 |
Gastritis erosive | 29.32 | 9.72 | 121 | 404772 | 10726 | 79328769 |
Autoimmune hepatitis | 29.19 | 9.72 | 128 | 404765 | 11655 | 79327840 |
Lymphocyte count decreased | 29.15 | 9.72 | 132 | 404761 | 47157 | 79292338 |
Rash papular | 29.14 | 9.72 | 201 | 404692 | 21715 | 79317780 |
Productive cough | 29.11 | 9.72 | 297 | 404596 | 88034 | 79251461 |
Dysarthria | 29.09 | 9.72 | 494 | 404399 | 67128 | 79272367 |
Head injury | 29.06 | 9.72 | 304 | 404589 | 37065 | 79302430 |
Hepatic cyst | 28.91 | 9.72 | 82 | 404811 | 6007 | 79333488 |
Febrile bone marrow aplasia | 28.86 | 9.72 | 15 | 404878 | 13005 | 79326490 |
Injection site swelling | 28.79 | 9.72 | 132 | 404761 | 47000 | 79292495 |
Vasculitis | 28.66 | 9.72 | 222 | 404671 | 24880 | 79314615 |
Hypokalaemia | 28.60 | 9.72 | 945 | 403948 | 143095 | 79196400 |
Actinic elastosis | 28.58 | 9.72 | 11 | 404882 | 50 | 79339445 |
Ear infection | 28.54 | 9.72 | 85 | 404808 | 34347 | 79305148 |
Intraventricular haemorrhage | 28.46 | 9.72 | 71 | 404822 | 4816 | 79334679 |
Wrong technique in product usage process | 28.40 | 9.72 | 239 | 404654 | 73636 | 79265859 |
Pancreatic steatosis | 28.39 | 9.72 | 32 | 404861 | 1113 | 79338382 |
Gout | 28.32 | 9.72 | 219 | 404674 | 24530 | 79314965 |
Myasthenia gravis | 28.11 | 9.72 | 116 | 404777 | 10283 | 79329212 |
Obstructive airways disorder | 28.04 | 9.72 | 75 | 404818 | 31384 | 79308111 |
Oral herpes | 27.99 | 9.72 | 61 | 404832 | 27393 | 79312102 |
Platelet count decreased | 27.97 | 9.72 | 763 | 404130 | 193901 | 79145594 |
Blood pressure diastolic abnormal | 27.68 | 9.72 | 34 | 404859 | 19168 | 79320327 |
Migraine | 27.68 | 9.72 | 297 | 404596 | 87196 | 79252299 |
Lower limb fracture | 27.66 | 9.72 | 47 | 404846 | 23168 | 79316327 |
Cold sweat | 27.58 | 9.72 | 176 | 404717 | 18523 | 79320972 |
Foetal death | 27.55 | 9.72 | 4 | 404889 | 8040 | 79331455 |
Spinal cord haemorrhage | 27.43 | 9.72 | 23 | 404870 | 551 | 79338944 |
Dilatation atrial | 27.27 | 9.72 | 59 | 404834 | 3645 | 79335850 |
Ubiquinone decreased | 27.02 | 9.72 | 9 | 404884 | 24 | 79339471 |
International normalised ratio abnormal | 26.72 | 9.72 | 77 | 404816 | 5691 | 79333804 |
International normalised ratio decreased | 26.71 | 9.72 | 96 | 404797 | 7974 | 79331521 |
Cardiac failure | 26.56 | 9.72 | 999 | 403894 | 153843 | 79185652 |
Blood pressure diastolic increased | 26.44 | 9.72 | 21 | 404872 | 14521 | 79324974 |
Carotid arteriosclerosis | 26.43 | 9.72 | 48 | 404845 | 2608 | 79336887 |
Immune reconstitution inflammatory syndrome | 26.43 | 9.72 | 19 | 404874 | 13822 | 79325673 |
Unresponsive to stimuli | 26.40 | 9.72 | 414 | 404479 | 55374 | 79284121 |
Tenosynovitis | 26.39 | 9.72 | 24 | 404869 | 15530 | 79323965 |
Exposure to toxic agent | 26.25 | 9.72 | 7 | 404886 | 9151 | 79330344 |
Blood phosphorus increased | 26.09 | 9.72 | 113 | 404780 | 10234 | 79329261 |
Adjustment disorder with depressed mood | 25.94 | 9.72 | 7 | 404886 | 9079 | 79330416 |
Liver function test increased | 25.74 | 9.72 | 109 | 404784 | 39664 | 79299831 |
Duodenitis | 25.72 | 9.72 | 94 | 404799 | 7873 | 79331622 |
Blood creatine phosphokinase MB increased | 25.72 | 9.72 | 49 | 404844 | 2762 | 79336733 |
Angioplasty | 25.71 | 9.72 | 39 | 404854 | 1824 | 79337671 |
Anhedonia | 25.66 | 9.72 | 146 | 404747 | 14752 | 79324743 |
Prescribed overdose | 25.66 | 9.72 | 102 | 404791 | 37781 | 79301714 |
Night sweats | 25.63 | 9.72 | 157 | 404736 | 51938 | 79287557 |
Posterior reversible encephalopathy syndrome | 25.49 | 9.72 | 60 | 404833 | 26221 | 79313274 |
Rectal haemorrhage | 25.45 | 9.72 | 536 | 404357 | 75764 | 79263731 |
Oropharyngeal pain | 25.43 | 9.72 | 396 | 404497 | 108957 | 79230538 |
Haemarthrosis | 25.41 | 9.72 | 76 | 404817 | 5736 | 79333759 |
Swelling face | 25.32 | 9.72 | 505 | 404388 | 70707 | 79268788 |
Femoral hernia incarcerated | 25.21 | 9.72 | 26 | 404867 | 816 | 79338679 |
Retinal artery thrombosis | 25.16 | 9.72 | 12 | 404881 | 100 | 79339395 |
Tuberculosis | 25.14 | 9.72 | 24 | 404869 | 15174 | 79324321 |
Ischaemia | 25.00 | 9.72 | 94 | 404799 | 7981 | 79331514 |
Aphasia | 24.92 | 9.72 | 354 | 404539 | 46378 | 79293117 |
Upper motor neurone lesion | 24.90 | 9.72 | 16 | 404877 | 250 | 79339245 |
Blood glucose abnormal | 24.83 | 9.72 | 113 | 404780 | 10453 | 79329042 |
Postprandial hypoglycaemia | 24.81 | 9.72 | 11 | 404882 | 76 | 79339419 |
Ejaculation failure | 24.78 | 9.72 | 18 | 404875 | 347 | 79339148 |
Sprue-like enteropathy | 24.77 | 9.72 | 32 | 404861 | 1286 | 79338209 |
Lip dry | 24.75 | 9.72 | 25 | 404868 | 15393 | 79324102 |
BK virus infection | 24.72 | 9.72 | 7 | 404886 | 8797 | 79330698 |
Laryngitis | 24.63 | 9.72 | 27 | 404866 | 16012 | 79323483 |
Colitis microscopic | 24.45 | 9.72 | 114 | 404779 | 10654 | 79328841 |
Autoimmune disorder | 24.39 | 9.72 | 29 | 404864 | 16583 | 79322912 |
Cytomegalovirus infection reactivation | 24.35 | 9.72 | 7 | 404886 | 8709 | 79330786 |
Lymphopenia | 24.21 | 9.72 | 77 | 404816 | 30480 | 79309015 |
Spontaneous haemorrhage | 24.05 | 9.72 | 25 | 404868 | 792 | 79338703 |
Red blood cell sedimentation rate increased | 23.90 | 9.72 | 136 | 404757 | 45806 | 79293689 |
Portal fibrosis | 23.89 | 9.72 | 22 | 404871 | 599 | 79338896 |
Wound infection | 23.89 | 9.72 | 54 | 404839 | 23937 | 79315558 |
Breast cancer stage II | 23.67 | 9.72 | 6 | 404887 | 8114 | 79331381 |
Hepatic function abnormal | 23.60 | 9.72 | 247 | 404646 | 72860 | 79266635 |
Myoglobin urine | 23.59 | 9.72 | 8 | 404885 | 23 | 79339472 |
Hallucination, visual | 23.47 | 9.72 | 262 | 404631 | 32467 | 79307028 |
Enthesopathy | 23.41 | 9.72 | 15 | 404878 | 11593 | 79327902 |
Urinary retention | 23.38 | 9.72 | 411 | 404482 | 56219 | 79283276 |
Hypomagnesaemia | 23.30 | 9.72 | 351 | 404542 | 46560 | 79292935 |
Granuloma annulare | 23.21 | 9.72 | 22 | 404871 | 622 | 79338873 |
Device dislocation | 23.08 | 9.72 | 62 | 404831 | 25908 | 79313587 |
Respiratory depression | 23.05 | 9.72 | 68 | 404825 | 27562 | 79311933 |
Facial paresis | 22.98 | 9.72 | 71 | 404822 | 5455 | 79334040 |
Cerebrospinal fluid retention | 22.93 | 9.72 | 11 | 404882 | 93 | 79339402 |
Cognitive disorder | 22.93 | 9.72 | 490 | 404403 | 69436 | 79270059 |
Hyperammonaemia | 22.84 | 9.72 | 14 | 404879 | 11079 | 79328416 |
Fear of injection | 22.82 | 9.72 | 5 | 404888 | 7469 | 79332026 |
Aortic valve sclerosis | 22.80 | 9.72 | 36 | 404857 | 1744 | 79337751 |
Cystitis haemorrhagic | 22.78 | 9.72 | 9 | 404884 | 9163 | 79330332 |
Visual impairment | 22.76 | 9.72 | 621 | 404272 | 91510 | 79247985 |
Nasal congestion | 22.58 | 9.72 | 264 | 404629 | 76288 | 79263207 |
Post procedural haemorrhage | 22.57 | 9.72 | 133 | 404760 | 13611 | 79325884 |
Electrolyte imbalance | 22.51 | 9.72 | 248 | 404645 | 30633 | 79308862 |
Cerebral artery thrombosis | 22.50 | 9.72 | 28 | 404865 | 1083 | 79338412 |
Neurotoxicity | 22.38 | 9.72 | 87 | 404806 | 32431 | 79307064 |
Drug use disorder | 22.30 | 9.72 | 8 | 404885 | 8643 | 79330852 |
Seroma | 22.17 | 9.72 | 41 | 404852 | 2259 | 79337236 |
Intentional self-injury | 22.14 | 9.72 | 87 | 404806 | 32332 | 79307163 |
Heart rate decreased | 22.12 | 9.72 | 239 | 404654 | 70077 | 79269418 |
Complication of device insertion | 22.12 | 9.72 | 3 | 404890 | 6347 | 79333148 |
Thrombotic thrombocytopenic purpura | 22.09 | 9.72 | 77 | 404816 | 6299 | 79333196 |
Alanine aminotransferase increased | 22.00 | 9.72 | 1023 | 403870 | 161547 | 79177948 |
Leukopenia | 21.96 | 9.72 | 438 | 404455 | 116075 | 79223420 |
Radiation inflammation | 21.94 | 9.72 | 25 | 404868 | 880 | 79338615 |
Pneumonia fungal | 21.92 | 9.72 | 15 | 404878 | 11195 | 79328300 |
Brain scan abnormal | 21.91 | 9.72 | 29 | 404864 | 1194 | 79338301 |
Abdominal pain lower | 21.70 | 9.72 | 252 | 404641 | 31530 | 79307965 |
Transplant dysfunction | 21.70 | 9.72 | 5 | 404888 | 7216 | 79332279 |
Scrotal oedema | 21.62 | 9.72 | 33 | 404860 | 1552 | 79337943 |
Candida infection | 21.61 | 9.72 | 110 | 404783 | 38104 | 79301391 |
Avoidant personality disorder | 21.60 | 9.72 | 6 | 404887 | 6 | 79339489 |
Spermatozoa abnormal | 21.60 | 9.72 | 6 | 404887 | 6 | 79339489 |
Occupational problem environmental | 21.60 | 9.72 | 6 | 404887 | 6 | 79339489 |
Lacunar infarction | 21.57 | 9.72 | 73 | 404820 | 5884 | 79333611 |
Cerebral ischaemia | 21.49 | 9.72 | 113 | 404780 | 11082 | 79328413 |
Exercise tolerance decreased | 21.31 | 9.72 | 97 | 404796 | 8974 | 79330521 |
SARS-CoV-2 test positive | 21.20 | 9.72 | 17 | 404876 | 11699 | 79327796 |
Malignant spinal cord compression | 21.20 | 9.72 | 12 | 404881 | 147 | 79339348 |
Chronic kidney disease | 21.19 | 9.72 | 462 | 404431 | 65692 | 79273803 |
Coeliac disease | 21.13 | 9.72 | 16 | 404877 | 11335 | 79328160 |
Gait inability | 21.01 | 9.72 | 418 | 404475 | 58499 | 79280996 |
Sickle cell anaemia with crisis | 20.99 | 9.72 | 7 | 404886 | 7915 | 79331580 |
Post viral fatigue syndrome | 20.98 | 9.72 | 16 | 404877 | 333 | 79339162 |
Cerebral arteriosclerosis | 20.96 | 9.72 | 23 | 404870 | 776 | 79338719 |
Periarthritis calcarea | 20.80 | 9.72 | 10 | 404883 | 85 | 79339410 |
Tachyarrhythmia | 20.69 | 9.72 | 80 | 404813 | 6882 | 79332613 |
Respiratory disorder | 20.62 | 9.72 | 138 | 404755 | 44718 | 79294777 |
Emotional distress | 20.61 | 9.72 | 301 | 404592 | 39668 | 79299827 |
Erythema dyschromicum perstans | 20.57 | 9.72 | 9 | 404884 | 60 | 79339435 |
Forced expiratory volume decreased | 20.53 | 9.72 | 7 | 404886 | 7807 | 79331688 |
Oesophagitis | 20.52 | 9.72 | 201 | 404692 | 24088 | 79315407 |
Dysuria | 20.40 | 9.72 | 368 | 404525 | 50583 | 79288912 |
Respiratory tract infection | 20.34 | 9.72 | 154 | 404739 | 48535 | 79290960 |
Eye pruritus | 20.29 | 9.72 | 176 | 404717 | 20394 | 79319101 |
Apolipoprotein A-I decreased | 20.18 | 9.72 | 7 | 404886 | 22 | 79339473 |
Platelet count normal | 20.18 | 9.72 | 7 | 404886 | 22 | 79339473 |
Uveitis | 20.12 | 9.72 | 34 | 404859 | 16796 | 79322699 |
Disability | 20.09 | 9.72 | 35 | 404858 | 17085 | 79322410 |
Dermatitis exfoliative | 19.90 | 9.72 | 108 | 404785 | 10721 | 79328774 |
Dystonia | 19.85 | 9.72 | 50 | 404843 | 21349 | 79318146 |
Linear IgA disease | 19.84 | 9.72 | 47 | 404846 | 3085 | 79336410 |
Sudden cardiac death | 19.78 | 9.72 | 65 | 404828 | 5160 | 79334335 |
Atrial flutter | 19.78 | 9.72 | 182 | 404711 | 21443 | 79318052 |
Ovarian cyst | 19.77 | 9.72 | 21 | 404872 | 12634 | 79326861 |
Osteochondrosis | 19.77 | 9.72 | 36 | 404857 | 1960 | 79337535 |
Vascular stent stenosis | 19.72 | 9.72 | 31 | 404862 | 1496 | 79337999 |
Uterine perforation | 19.69 | 9.72 | 4 | 404889 | 6299 | 79333196 |
Cerebrovascular disorder | 19.69 | 9.72 | 52 | 404841 | 3653 | 79335842 |
Biliary cirrhosis | 19.63 | 9.72 | 12 | 404881 | 171 | 79339324 |
Respiratory arrest | 19.59 | 9.72 | 192 | 404701 | 57358 | 79282137 |
Ocular myasthenia | 19.52 | 9.72 | 16 | 404877 | 371 | 79339124 |
Systemic candida | 19.46 | 9.72 | 5 | 404888 | 6701 | 79332794 |
Breast cancer stage I | 19.43 | 9.72 | 5 | 404888 | 6695 | 79332800 |
Rhinovirus infection | 19.43 | 9.72 | 8 | 404885 | 7945 | 79331550 |
Oesophageal obstruction | 19.42 | 9.72 | 25 | 404868 | 1001 | 79338494 |
Gastritis | 19.35 | 9.72 | 347 | 404546 | 47646 | 79291849 |
Speech disorder | 19.32 | 9.72 | 386 | 404507 | 54059 | 79285436 |
Duodenal ulcer repair | 19.29 | 9.72 | 9 | 404884 | 71 | 79339424 |
Ventricular hypertrophy | 19.23 | 9.72 | 78 | 404815 | 6860 | 79332635 |
Drug level decreased | 19.23 | 9.72 | 27 | 404866 | 14375 | 79325120 |
Drug specific antibody present | 19.22 | 9.72 | 5 | 404888 | 6647 | 79332848 |
Food allergy | 19.22 | 9.72 | 16 | 404877 | 10808 | 79328687 |
Lymphatic fistula | 19.16 | 9.72 | 22 | 404871 | 781 | 79338714 |
Subacute hepatic failure | 19.14 | 9.72 | 13 | 404880 | 224 | 79339271 |
Therapy cessation | 19.11 | 9.72 | 112 | 404781 | 37450 | 79302045 |
Tricuspid valve incompetence | 19.11 | 9.72 | 168 | 404725 | 19544 | 79319951 |
Pulmonary tuberculosis | 19.07 | 9.72 | 8 | 404885 | 7857 | 79331638 |
Injection site rash | 19.05 | 9.72 | 39 | 404854 | 17915 | 79321580 |
Neuropathy, ataxia, retinitis pigmentosa syndrome | 18.98 | 9.72 | 8 | 404885 | 48 | 79339447 |
Diabetic neuropathy | 18.95 | 9.72 | 72 | 404821 | 6144 | 79333351 |
Ageusia | 18.94 | 9.72 | 147 | 404746 | 16485 | 79323010 |
Tongue oedema | 18.93 | 9.72 | 79 | 404814 | 7038 | 79332457 |
No adverse event | 18.87 | 9.72 | 111 | 404782 | 37081 | 79302414 |
Sodium retention | 18.82 | 9.72 | 12 | 404881 | 185 | 79339310 |
Product dose omission in error | 18.76 | 9.72 | 8 | 404885 | 7780 | 79331715 |
Extrasystoles | 18.69 | 9.72 | 81 | 404812 | 7338 | 79332157 |
Cardio-respiratory arrest | 18.66 | 9.72 | 414 | 404479 | 108096 | 79231399 |
Bundle branch block left | 18.64 | 9.72 | 111 | 404782 | 11402 | 79328093 |
Femoral neck fracture | 18.64 | 9.72 | 100 | 404793 | 9884 | 79329611 |
Enterocolitis | 18.59 | 9.72 | 28 | 404865 | 14484 | 79325011 |
Hyperbilirubinaemia | 18.59 | 9.72 | 63 | 404830 | 24455 | 79315040 |
Carcinogenicity | 18.57 | 9.72 | 9 | 404884 | 78 | 79339417 |
Ketoacidosis | 18.46 | 9.72 | 84 | 404809 | 7770 | 79331725 |
Spinal osteoarthritis | 18.39 | 9.72 | 148 | 404745 | 16779 | 79322716 |
Incorrect route of product administration | 18.39 | 9.72 | 103 | 404790 | 34826 | 79304669 |
Blood test abnormal | 18.34 | 9.72 | 39 | 404854 | 17671 | 79321824 |
Hiatus hernia | 18.29 | 9.72 | 190 | 404703 | 23122 | 79316373 |
Erosive duodenitis | 18.26 | 9.72 | 36 | 404857 | 2081 | 79337414 |
Cerebral artery occlusion | 18.26 | 9.72 | 32 | 404861 | 1690 | 79337805 |
Pulmonary fibrosis | 18.16 | 9.72 | 320 | 404573 | 43792 | 79295703 |
Sensory disturbance | 18.14 | 9.72 | 135 | 404758 | 14942 | 79324553 |
Pneumatosis intestinalis | 18.13 | 9.72 | 5 | 404888 | 6392 | 79333103 |
Cytomegalovirus test positive | 18.11 | 9.72 | 4 | 404889 | 5943 | 79333552 |
Helicobacter gastritis | 18.02 | 9.72 | 39 | 404854 | 2410 | 79337085 |
Urinary incontinence | 18.01 | 9.72 | 300 | 404593 | 40609 | 79298886 |
Memory impairment | 18.00 | 9.72 | 716 | 404177 | 111018 | 79228477 |
Complications of transplanted kidney | 17.99 | 9.72 | 5 | 404888 | 6361 | 79333134 |
Dyspnoea exertional | 17.99 | 9.72 | 574 | 404319 | 86499 | 79252996 |
Viral myositis | 17.83 | 9.72 | 8 | 404885 | 57 | 79339438 |
Mitochondrial myopathy acquired | 17.82 | 9.72 | 7 | 404886 | 34 | 79339461 |
Nodular rash | 17.74 | 9.72 | 14 | 404879 | 307 | 79339188 |
Normochromic normocytic anaemia | 17.69 | 9.72 | 82 | 404811 | 7645 | 79331850 |
Altered state of consciousness | 17.65 | 9.72 | 140 | 404753 | 43682 | 79295813 |
Polyneuropathy | 17.63 | 9.72 | 194 | 404699 | 23957 | 79315538 |
Malnutrition | 17.62 | 9.72 | 57 | 404836 | 22445 | 79317050 |
Liver disorder | 17.60 | 9.72 | 260 | 404633 | 72157 | 79267338 |
Hypogammaglobulinaemia | 17.57 | 9.72 | 24 | 404869 | 12927 | 79326568 |
Akathisia | 17.56 | 9.72 | 25 | 404868 | 13234 | 79326261 |
Left ventricular hypertrophy | 17.55 | 9.72 | 107 | 404786 | 11084 | 79328411 |
Blood cholesterol increased | 17.55 | 9.72 | 309 | 404584 | 83411 | 79256084 |
Genital haemorrhage | 17.52 | 9.72 | 5 | 404888 | 6250 | 79333245 |
Leukocyturia | 17.45 | 9.72 | 34 | 404859 | 1949 | 79337546 |
Genital swelling | 17.40 | 9.72 | 14 | 404879 | 316 | 79339179 |
Gastric ulcer | 17.35 | 9.72 | 255 | 404638 | 33650 | 79305845 |
Pleurothotonus | 17.30 | 9.72 | 39 | 404854 | 2477 | 79337018 |
Dysphagia | 17.27 | 9.72 | 772 | 404121 | 121364 | 79218131 |
Myxoedema coma | 17.26 | 9.72 | 20 | 404873 | 717 | 79338778 |
Bronchitis | 17.26 | 9.72 | 518 | 404375 | 130126 | 79209369 |
Left ventricular failure | 17.23 | 9.72 | 95 | 404798 | 9486 | 79330009 |
Hypothermia | 17.19 | 9.72 | 184 | 404709 | 22562 | 79316933 |
Pseudomonal sepsis | 17.17 | 9.72 | 5 | 404888 | 6169 | 79333326 |
Poisoning | 17.14 | 9.72 | 68 | 404825 | 25204 | 79314291 |
Acquired claw toe | 17.13 | 9.72 | 9 | 404884 | 94 | 79339401 |
Cerebral ventricular rupture | 17.13 | 9.72 | 16 | 404877 | 444 | 79339051 |
Intestinal obstruction | 17.07 | 9.72 | 138 | 404755 | 42882 | 79296613 |
Device malfunction | 17.03 | 9.72 | 54 | 404839 | 21394 | 79318101 |
Sleep attacks | 17.01 | 9.72 | 11 | 404882 | 174 | 79339321 |
Cerebellar ataxia | 16.98 | 9.72 | 33 | 404860 | 1888 | 79337607 |
Blood sodium decreased | 16.97 | 9.72 | 250 | 404643 | 33005 | 79306490 |
Hypoglycaemic coma | 16.94 | 9.72 | 58 | 404835 | 4702 | 79334793 |
Anal fistula | 16.94 | 9.72 | 7 | 404886 | 6937 | 79332558 |
Biopsy muscle abnormal | 16.89 | 9.72 | 7 | 404886 | 40 | 79339455 |
Amenorrhoea | 16.85 | 9.72 | 9 | 404884 | 7683 | 79331812 |
Polymyalgia rheumatica | 16.78 | 9.72 | 56 | 404837 | 4481 | 79335014 |
Alveolitis | 16.73 | 9.72 | 53 | 404840 | 4127 | 79335368 |
Coronary artery bypass | 16.68 | 9.72 | 68 | 404825 | 5994 | 79333501 |
Hepatitis cholestatic | 16.65 | 9.72 | 124 | 404769 | 13728 | 79325767 |
Blood pressure increased | 16.65 | 9.72 | 890 | 404003 | 210470 | 79129025 |
Contracted bladder | 16.60 | 9.72 | 6 | 404887 | 22 | 79339473 |
Mydriasis | 16.54 | 9.72 | 41 | 404852 | 17602 | 79321893 |
Brain oedema | 16.49 | 9.72 | 69 | 404824 | 25194 | 79314301 |
Prothrombin time abnormal | 16.48 | 9.72 | 24 | 404869 | 1082 | 79338413 |
Electromyogram abnormal | 16.45 | 9.72 | 10 | 404883 | 141 | 79339354 |
Torsade de pointes | 16.40 | 9.72 | 160 | 404733 | 19152 | 79320343 |
Product administered to patient of inappropriate age | 16.38 | 9.72 | 4 | 404889 | 5549 | 79333946 |
Atrioventricular block second degree | 16.30 | 9.72 | 77 | 404816 | 7235 | 79332260 |
Cardiotoxicity | 16.28 | 9.72 | 23 | 404870 | 12216 | 79327279 |
Hepatitis C | 16.28 | 9.72 | 22 | 404871 | 11903 | 79327592 |
Adverse drug reaction | 16.26 | 9.72 | 238 | 404655 | 66154 | 79273341 |
Groin pain | 16.24 | 9.72 | 118 | 404775 | 12962 | 79326533 |
Epistaxis | 16.24 | 9.72 | 707 | 404186 | 110808 | 79228687 |
Arteriosclerotic gangrene | 16.16 | 9.72 | 8 | 404885 | 73 | 79339422 |
Adverse event | 16.12 | 9.72 | 212 | 404681 | 60002 | 79279493 |
Joint destruction | 16.11 | 9.72 | 5 | 404888 | 5920 | 79333575 |
Cytomegalovirus chorioretinitis | 16.11 | 9.72 | 4 | 404889 | 5486 | 79334009 |
Lid lag | 16.06 | 9.72 | 8 | 404885 | 74 | 79339421 |
Aortic aneurysm | 16.04 | 9.72 | 85 | 404808 | 8361 | 79331134 |
Joint effusion | 16.01 | 9.72 | 43 | 404850 | 17971 | 79321524 |
Respiratory tract congestion | 16.01 | 9.72 | 50 | 404843 | 19904 | 79319591 |
Metabolic acidosis | 16.01 | 9.72 | 540 | 404353 | 81989 | 79257506 |
Areflexia | 15.97 | 9.72 | 63 | 404830 | 5471 | 79334024 |
Pharyngitis | 15.95 | 9.72 | 59 | 404834 | 22316 | 79317179 |
Supraventricular extrasystoles | 15.88 | 9.72 | 74 | 404819 | 6913 | 79332582 |
Spontaneous haematoma | 15.83 | 9.72 | 27 | 404866 | 1395 | 79338100 |
Temperature regulation disorder | 15.81 | 9.72 | 5 | 404888 | 5848 | 79333647 |
Product complaint | 15.77 | 9.72 | 119 | 404774 | 13230 | 79326265 |
Long QT syndrome | 15.76 | 9.72 | 66 | 404827 | 5889 | 79333606 |
Mobility decreased | 15.75 | 9.72 | 486 | 404407 | 121689 | 79217806 |
Muscle spasticity | 15.73 | 9.72 | 56 | 404837 | 21419 | 79318076 |
Encephalopathy | 15.69 | 9.72 | 244 | 404649 | 67153 | 79272342 |
X-ray abnormal | 15.64 | 9.72 | 5 | 404888 | 5808 | 79333687 |
Blood electrolytes abnormal | 15.62 | 9.72 | 32 | 404861 | 1902 | 79337593 |
Disseminated intravascular coagulation | 15.62 | 9.72 | 112 | 404781 | 35730 | 79303765 |
Clostridium difficile infection | 15.56 | 9.72 | 140 | 404753 | 42545 | 79296950 |
White blood cell count increased | 15.42 | 9.72 | 492 | 404401 | 74141 | 79265354 |
Pharyngitis streptococcal | 15.41 | 9.72 | 19 | 404874 | 10695 | 79328800 |
Respiratory syncytial virus infection | 15.37 | 9.72 | 15 | 404878 | 9387 | 79330108 |
Second primary malignancy | 15.37 | 9.72 | 31 | 404862 | 14319 | 79325176 |
Abdominal distension | 15.35 | 9.72 | 749 | 404144 | 118901 | 79220594 |
Blood triglycerides increased | 15.35 | 9.72 | 169 | 404724 | 20871 | 79318624 |
Gastric disorder | 15.35 | 9.72 | 119 | 404774 | 37314 | 79302181 |
Prothrombin time prolonged | 15.34 | 9.72 | 142 | 404751 | 16757 | 79322738 |
Aortic stenosis | 15.32 | 9.72 | 77 | 404816 | 7418 | 79332077 |
Adrenal cyst | 15.31 | 9.72 | 10 | 404883 | 161 | 79339334 |
Paralysis | 15.30 | 9.72 | 117 | 404776 | 13060 | 79326435 |
Hand-eye coordination impaired | 15.29 | 9.72 | 6 | 404887 | 29 | 79339466 |
Parakeratosis | 15.24 | 9.72 | 14 | 404879 | 380 | 79339115 |
Coronary arterial stent insertion | 15.23 | 9.72 | 66 | 404827 | 5978 | 79333517 |
Prostatic specific antigen abnormal | 15.21 | 9.72 | 15 | 404878 | 446 | 79339049 |
Blood lactic acid | 15.15 | 9.72 | 15 | 404878 | 448 | 79339047 |
Angioimmunoblastic T-cell lymphoma | 15.12 | 9.72 | 15 | 404878 | 449 | 79339046 |
Parainfluenzae virus infection | 15.09 | 9.72 | 5 | 404888 | 5677 | 79333818 |
Colorectal cancer | 15.08 | 9.72 | 13 | 404880 | 8634 | 79330861 |
Nocardiosis | 15.08 | 9.72 | 5 | 404888 | 5674 | 79333821 |
Renal cyst | 15.03 | 9.72 | 127 | 404766 | 14605 | 79324890 |
Orthopnoea | 14.97 | 9.72 | 95 | 404798 | 9978 | 79329517 |
Sciatica | 14.88 | 9.72 | 103 | 404790 | 33119 | 79306376 |
Aortic valve incompetence | 14.87 | 9.72 | 91 | 404802 | 9439 | 79330056 |
Mitral valve stenosis | 14.85 | 9.72 | 24 | 404869 | 1186 | 79338309 |
Bundle branch block right | 14.84 | 9.72 | 103 | 404790 | 11148 | 79328347 |
Bladder trabeculation | 14.82 | 9.72 | 7 | 404886 | 57 | 79339438 |
Status epilepticus | 14.78 | 9.72 | 71 | 404822 | 24970 | 79314525 |
Cushingoid | 14.76 | 9.72 | 16 | 404877 | 9536 | 79329959 |
Hypertensive heart disease | 14.75 | 9.72 | 51 | 404842 | 4155 | 79335340 |
Coronavirus infection | 14.70 | 9.72 | 10 | 404883 | 7487 | 79332008 |
Arterial haemorrhage | 14.70 | 9.72 | 37 | 404856 | 2524 | 79336971 |
Coronary angioplasty | 14.68 | 9.72 | 14 | 404879 | 399 | 79339096 |
Bladder obstruction | 14.64 | 9.72 | 15 | 404878 | 467 | 79339028 |
Full blood count abnormal | 14.64 | 9.72 | 133 | 404760 | 40341 | 79299154 |
Diverticulum intestinal | 14.60 | 9.72 | 84 | 404809 | 8521 | 79330974 |
Puncture site haematoma | 14.59 | 9.72 | 10 | 404883 | 175 | 79339320 |
Aplasia | 14.59 | 9.72 | 11 | 404882 | 7809 | 79331686 |
Penile curvature | 14.59 | 9.72 | 5 | 404888 | 15 | 79339480 |
Macroenzyme creatine kinase | 14.59 | 9.72 | 5 | 404888 | 15 | 79339480 |
Brucellosis | 14.56 | 9.72 | 9 | 404884 | 131 | 79339364 |
Pancreatic carcinoma metastatic | 14.49 | 9.72 | 47 | 404846 | 3706 | 79335789 |
Diabetic hyperosmolar coma | 14.43 | 9.72 | 19 | 404874 | 778 | 79338717 |
Pneumonia bacterial | 14.43 | 9.72 | 50 | 404843 | 19281 | 79320214 |
Glycogen storage disease type II | 14.40 | 9.72 | 4 | 404889 | 4 | 79339491 |
Embolic stroke | 14.35 | 9.72 | 78 | 404815 | 7748 | 79331747 |
Nodule | 14.28 | 9.72 | 64 | 404829 | 22930 | 79316565 |
Device breakage | 14.26 | 9.72 | 20 | 404873 | 10655 | 79328840 |
Degenerative aortic valve disease | 14.26 | 9.72 | 10 | 404883 | 182 | 79339313 |
Exercise lack of | 14.24 | 9.72 | 15 | 404878 | 483 | 79339012 |
Duodenal ulcer haemorrhage | 14.23 | 9.72 | 73 | 404820 | 7090 | 79332405 |
Palmar-plantar erythrodysaesthesia syndrome | 14.22 | 9.72 | 104 | 404789 | 33030 | 79306465 |
Endocrine ophthalmopathy | 14.19 | 9.72 | 18 | 404875 | 710 | 79338785 |
Vertebral artery stenosis | 14.16 | 9.72 | 10 | 404883 | 184 | 79339311 |
AST/ALT ratio abnormal | 14.12 | 9.72 | 5 | 404888 | 17 | 79339478 |
Blepharospasm | 14.11 | 9.72 | 6 | 404887 | 5845 | 79333650 |
Crystal nephropathy | 14.10 | 9.72 | 26 | 404867 | 1429 | 79338066 |
Venoocclusive disease | 14.08 | 9.72 | 3 | 404890 | 4570 | 79334925 |
Frequent bowel movements | 14.02 | 9.72 | 90 | 404803 | 29449 | 79310046 |
Drug tolerance | 14.00 | 9.72 | 14 | 404879 | 8661 | 79330834 |
Metastases to bone | 13.99 | 9.72 | 70 | 404823 | 24357 | 79315138 |
Subdural hygroma | 13.96 | 9.72 | 15 | 404878 | 494 | 79339001 |
Ureteric injury | 13.93 | 9.72 | 9 | 404884 | 142 | 79339353 |
Multiple sclerosis relapse | 13.91 | 9.72 | 160 | 404733 | 46373 | 79293122 |
Catheter site pain | 13.89 | 9.72 | 5 | 404888 | 5391 | 79334104 |
Parkinsonism | 13.89 | 9.72 | 137 | 404756 | 16447 | 79323048 |
Hypoglycaemic unconsciousness | 13.89 | 9.72 | 23 | 404870 | 1160 | 79338335 |
Hypovolaemia | 13.79 | 9.72 | 144 | 404749 | 17547 | 79321948 |
Lipase increased | 13.78 | 9.72 | 136 | 404757 | 16330 | 79323165 |
Lumbar radiculopathy | 13.76 | 9.72 | 31 | 404862 | 1968 | 79337527 |
Blood urine | 13.76 | 9.72 | 20 | 404873 | 900 | 79338595 |
Shock hypoglycaemic | 13.76 | 9.72 | 11 | 404882 | 246 | 79339249 |
Urine output decreased | 13.72 | 9.72 | 146 | 404747 | 17876 | 79321619 |
Cerebral infarction | 13.69 | 9.72 | 316 | 404577 | 45360 | 79294135 |
Hepatitis B reactivation | 13.59 | 9.72 | 7 | 404886 | 6101 | 79333394 |
Job dissatisfaction | 13.59 | 9.72 | 7 | 404886 | 70 | 79339425 |
Polyuria | 13.55 | 9.72 | 126 | 404767 | 14888 | 79324607 |
Colitis ulcerative | 13.53 | 9.72 | 112 | 404781 | 34630 | 79304865 |
Diverticulum intestinal haemorrhagic | 13.52 | 9.72 | 48 | 404845 | 3963 | 79335532 |
Aortic valve stenosis | 13.49 | 9.72 | 58 | 404835 | 5236 | 79334259 |
Ventricular hypokinesia | 13.48 | 9.72 | 87 | 404806 | 9192 | 79330303 |
Osteoma | 13.46 | 9.72 | 8 | 404885 | 108 | 79339387 |
Antipsychotic drug level decreased | 13.31 | 9.72 | 23 | 404870 | 1201 | 79338294 |
Interstitial lung disease | 13.30 | 9.72 | 453 | 404440 | 112147 | 79227348 |
Secretion discharge | 13.25 | 9.72 | 36 | 404857 | 14986 | 79324509 |
Nail disorder | 13.22 | 9.72 | 25 | 404868 | 11827 | 79327668 |
Carotid bruit | 13.16 | 9.72 | 18 | 404875 | 765 | 79338730 |
Carcinoma in situ | 13.15 | 9.72 | 8 | 404885 | 113 | 79339382 |
Lichen myxoedematosus | 13.12 | 9.72 | 6 | 404887 | 45 | 79339450 |
Rheumatoid nodule | 13.09 | 9.72 | 45 | 404848 | 17393 | 79322102 |
Epiglottic oedema | 13.05 | 9.72 | 12 | 404881 | 326 | 79339169 |
Non-cardiac chest pain | 13.05 | 9.72 | 88 | 404805 | 9436 | 79330059 |
Vasculitic rash | 13.00 | 9.72 | 32 | 404861 | 2152 | 79337343 |
Wound dehiscence | 12.96 | 9.72 | 67 | 404826 | 6528 | 79332967 |
Injected limb mobility decreased | 12.94 | 9.72 | 5 | 404888 | 23 | 79339472 |
Acetonaemia | 12.93 | 9.72 | 12 | 404881 | 330 | 79339165 |
Intestinal angioedema | 12.92 | 9.72 | 19 | 404874 | 864 | 79338631 |
Loose tooth | 12.92 | 9.72 | 40 | 404853 | 3077 | 79336418 |
Bronchiectasis | 12.91 | 9.72 | 64 | 404829 | 22322 | 79317173 |
Klebsiella infection | 12.89 | 9.72 | 39 | 404854 | 15681 | 79323814 |
Auricular swelling | 12.87 | 9.72 | 9 | 404884 | 163 | 79339332 |
Wrong patient received product | 12.87 | 9.72 | 52 | 404841 | 4566 | 79334929 |
Faecal calprotectin increased | 12.86 | 9.72 | 6 | 404887 | 5535 | 79333960 |
Fracture blisters | 12.86 | 9.72 | 7 | 404886 | 79 | 79339416 |
Neuromyopathy | 12.85 | 9.72 | 26 | 404867 | 1532 | 79337963 |
Heart rate increased | 12.83 | 9.72 | 492 | 404401 | 120232 | 79219263 |
Intra-abdominal haematoma | 12.83 | 9.72 | 38 | 404855 | 2853 | 79336642 |
Polycystic liver disease | 12.82 | 9.72 | 9 | 404884 | 164 | 79339331 |
Depressed level of consciousness | 12.82 | 9.72 | 383 | 404510 | 96269 | 79243226 |
Hepatitis toxic | 12.81 | 9.72 | 56 | 404837 | 5091 | 79334404 |
Carnitine palmitoyltransferase deficiency | 12.80 | 9.72 | 4 | 404889 | 8 | 79339487 |
Low turnover osteopathy | 12.79 | 9.72 | 30 | 404863 | 1956 | 79337539 |
Pancreatic carcinoma | 12.79 | 9.72 | 115 | 404778 | 13462 | 79326033 |
Body temperature increased | 12.79 | 9.72 | 154 | 404739 | 44266 | 79295229 |
Eye swelling | 12.74 | 9.72 | 197 | 404696 | 26271 | 79313224 |
Arterial occlusive disease | 12.72 | 9.72 | 80 | 404813 | 8376 | 79331119 |
Paresis | 12.69 | 9.72 | 49 | 404844 | 4212 | 79335283 |
Eye haemorrhage | 12.68 | 9.72 | 89 | 404804 | 9668 | 79329827 |
Foot deformity | 12.67 | 9.72 | 71 | 404822 | 24003 | 79315492 |
Cytomegalovirus colitis | 12.66 | 9.72 | 4 | 404889 | 4681 | 79334814 |
Brain stem infarction | 12.64 | 9.72 | 30 | 404863 | 1971 | 79337524 |
Vascular graft occlusion | 12.64 | 9.72 | 17 | 404876 | 711 | 79338784 |
Muscle fatigue | 12.63 | 9.72 | 43 | 404850 | 3476 | 79336019 |
Muscle discomfort | 12.63 | 9.72 | 11 | 404882 | 278 | 79339217 |
Blood pressure difference of extremities | 12.61 | 9.72 | 5 | 404888 | 25 | 79339470 |
Extremity necrosis | 12.58 | 9.72 | 40 | 404853 | 3121 | 79336374 |
Serum ferritin abnormal | 12.56 | 9.72 | 13 | 404880 | 410 | 79339085 |
Cardiac stress test abnormal | 12.55 | 9.72 | 18 | 404875 | 800 | 79338695 |
Splenic necrosis | 12.54 | 9.72 | 9 | 404884 | 170 | 79339325 |
Lymphadenitis | 12.53 | 9.72 | 4 | 404889 | 4651 | 79334844 |
Dental examination abnormal | 12.48 | 9.72 | 4 | 404889 | 9 | 79339486 |
Electrolyte depletion | 12.48 | 9.72 | 13 | 404880 | 413 | 79339082 |
Conjunctival discolouration | 12.45 | 9.72 | 8 | 404885 | 125 | 79339370 |
Skin infection | 12.43 | 9.72 | 49 | 404844 | 18196 | 79321299 |
Feeling abnormal | 12.43 | 9.72 | 954 | 403939 | 158245 | 79181250 |
Menstruation irregular | 12.41 | 9.72 | 5 | 404888 | 5031 | 79334464 |
Food interaction | 12.40 | 9.72 | 27 | 404866 | 1675 | 79337820 |
Pollakiuria | 12.39 | 9.72 | 262 | 404631 | 37055 | 79302440 |
Hypomania | 12.38 | 9.72 | 12 | 404881 | 7532 | 79331963 |
Subacute cutaneous lupus erythematosus | 12.34 | 9.72 | 43 | 404850 | 3518 | 79335977 |
Osteonecrosis of external auditory canal | 12.32 | 9.72 | 9 | 404884 | 175 | 79339320 |
Infarction | 12.30 | 9.72 | 51 | 404842 | 4531 | 79334964 |
Femoral artery embolism | 12.28 | 9.72 | 6 | 404887 | 53 | 79339442 |
Carotid artery disease | 12.26 | 9.72 | 32 | 404861 | 2232 | 79337263 |
Injection site haemorrhage | 12.19 | 9.72 | 87 | 404806 | 27783 | 79311712 |
Wound infection pseudomonas | 12.14 | 9.72 | 26 | 404867 | 1595 | 79337900 |
Pneumonia cytomegaloviral | 12.14 | 9.72 | 5 | 404888 | 4964 | 79334531 |
Malaise | 12.12 | 9.72 | 2736 | 402157 | 487133 | 78852362 |
Neuropathic muscular atrophy | 12.09 | 9.72 | 6 | 404887 | 55 | 79339440 |
Nephrolithiasis | 12.04 | 9.72 | 194 | 404699 | 53097 | 79286398 |
Neoplasm prostate | 12.02 | 9.72 | 9 | 404884 | 182 | 79339313 |
Flatulence | 12.01 | 9.72 | 293 | 404600 | 42431 | 79297064 |
Pharyngeal oedema | 12.01 | 9.72 | 131 | 404762 | 16141 | 79323354 |
Change of bowel habit | 12.00 | 9.72 | 36 | 404857 | 2721 | 79336774 |
Alcohol use disorder | 12.00 | 9.72 | 5 | 404888 | 29 | 79339466 |
Poliomyelitis | 12 | 9.72 | 6 | 404887 | 56 | 79339439 |
Coronavirus test positive | 12.00 | 9.72 | 21 | 404872 | 1108 | 79338387 |
Listless | 12.00 | 9.72 | 45 | 404848 | 3816 | 79335679 |
Sinus disorder | 11.96 | 9.72 | 66 | 404827 | 22398 | 79317097 |
Hepatocellular carcinoma | 11.96 | 9.72 | 17 | 404876 | 9004 | 79330491 |
Blood pressure diastolic decreased | 11.95 | 9.72 | 97 | 404796 | 30119 | 79309376 |
Staphylococcal infection | 11.95 | 9.72 | 216 | 404677 | 58079 | 79281416 |
Fungal infection | 11.92 | 9.72 | 145 | 404748 | 41603 | 79297892 |
Intrapericardial thrombosis | 11.91 | 9.72 | 6 | 404887 | 57 | 79339438 |
Orbital swelling | 11.91 | 9.72 | 6 | 404887 | 57 | 79339438 |
Aortic valve calcification | 11.90 | 9.72 | 17 | 404876 | 753 | 79338742 |
Sinus rhythm | 11.89 | 9.72 | 18 | 404875 | 840 | 79338655 |
Prostate cancer metastatic | 11.87 | 9.72 | 46 | 404847 | 3961 | 79335534 |
Lordosis | 11.86 | 9.72 | 13 | 404880 | 438 | 79339057 |
Sensitivity to weather change | 11.86 | 9.72 | 14 | 404879 | 8033 | 79331462 |
Vulvar basal cell carcinoma | 11.86 | 9.72 | 5 | 404888 | 30 | 79339465 |
Deformity | 11.86 | 9.72 | 19 | 404874 | 9586 | 79329909 |
Liver injury | 11.85 | 9.72 | 209 | 404684 | 56405 | 79283090 |
Pancreatic duct stenosis | 11.84 | 9.72 | 10 | 404883 | 242 | 79339253 |
Dysgeusia | 11.83 | 9.72 | 377 | 404516 | 56800 | 79282695 |
Anaphylactic reaction | 11.82 | 9.72 | 329 | 404564 | 83414 | 79256081 |
Osteoarthritis | 11.82 | 9.72 | 345 | 404548 | 86964 | 79252531 |
Central nervous system lesion | 11.81 | 9.72 | 32 | 404861 | 13336 | 79326159 |
Gilbert's syndrome | 11.73 | 9.72 | 5 | 404888 | 31 | 79339464 |
Parotid gland haemorrhage | 11.73 | 9.72 | 5 | 404888 | 31 | 79339464 |
Haemoglobin decreased | 11.72 | 9.72 | 1294 | 403599 | 220825 | 79118670 |
Toxic shock syndrome | 11.71 | 9.72 | 22 | 404871 | 1227 | 79338268 |
Erythema | 11.70 | 9.72 | 975 | 403918 | 222315 | 79117180 |
Flushing | 11.65 | 9.72 | 350 | 404543 | 87918 | 79251577 |
Personality change | 11.64 | 9.72 | 90 | 404803 | 10080 | 79329415 |
Nasal polyps | 11.63 | 9.72 | 12 | 404881 | 7315 | 79332180 |
Gastroenteritis viral | 11.61 | 9.72 | 76 | 404817 | 24755 | 79314740 |
Dermatitis bullous | 11.60 | 9.72 | 117 | 404776 | 14128 | 79325367 |
Basal ganglia haemorrhage | 11.60 | 9.72 | 26 | 404867 | 1645 | 79337850 |
Anaemia vitamin B12 deficiency | 11.60 | 9.72 | 17 | 404876 | 771 | 79338724 |
Diffuse large B-cell lymphoma | 11.57 | 9.72 | 28 | 404865 | 12121 | 79327374 |
Syringe issue | 11.57 | 9.72 | 9 | 404884 | 6289 | 79333206 |
Preternatural anus | 11.56 | 9.72 | 7 | 404886 | 98 | 79339397 |
Urinary bladder polyp | 11.54 | 9.72 | 10 | 404883 | 251 | 79339244 |
Illness anxiety disorder | 11.54 | 9.72 | 10 | 404883 | 251 | 79339244 |
Cutis laxa | 11.48 | 9.72 | 8 | 404885 | 144 | 79339351 |
Dry eye | 11.42 | 9.72 | 126 | 404767 | 36805 | 79302690 |
Device related infection | 11.42 | 9.72 | 115 | 404778 | 34179 | 79305316 |
Pneumonia viral | 11.42 | 9.72 | 18 | 404875 | 9140 | 79330355 |
Pseudoporphyria | 11.42 | 9.72 | 15 | 404878 | 613 | 79338882 |
Infusion site erythema | 11.41 | 9.72 | 19 | 404874 | 9441 | 79330054 |
Psychiatric decompensation | 11.41 | 9.72 | 3 | 404890 | 3960 | 79335535 |
Prerenal failure | 11.41 | 9.72 | 43 | 404850 | 3655 | 79335840 |
Drug dose omission by device | 11.39 | 9.72 | 9 | 404884 | 6241 | 79333254 |
Impatience | 11.34 | 9.72 | 15 | 404878 | 617 | 79338878 |
Femoral artery aneurysm | 11.34 | 9.72 | 9 | 404884 | 199 | 79339296 |
Nasal ulcer | 11.33 | 9.72 | 30 | 404863 | 2110 | 79337385 |
Movement disorder | 11.31 | 9.72 | 198 | 404695 | 27061 | 79312434 |
Mean cell haemoglobin decreased | 11.30 | 9.72 | 9 | 404884 | 6215 | 79333280 |
Hepatic encephalopathy | 11.28 | 9.72 | 74 | 404819 | 24092 | 79315403 |
Erythromelalgia | 11.26 | 9.72 | 9 | 404884 | 201 | 79339294 |
Barrett's oesophagus | 11.25 | 9.72 | 17 | 404876 | 792 | 79338703 |
Cerebral haematoma | 11.25 | 9.72 | 74 | 404819 | 7868 | 79331627 |
Respiratory fatigue | 11.24 | 9.72 | 10 | 404883 | 260 | 79339235 |
Disorientation | 11.24 | 9.72 | 407 | 404486 | 62369 | 79277126 |
Tongue disorder | 11.22 | 9.72 | 35 | 404858 | 13940 | 79325555 |
Epididymitis | 11.20 | 9.72 | 28 | 404865 | 1902 | 79337593 |
Lipodystrophy acquired | 11.15 | 9.72 | 4 | 404889 | 4321 | 79335174 |
Large intestine polyp | 11.15 | 9.72 | 106 | 404787 | 12602 | 79326893 |
Paradoxical drug reaction | 11.14 | 9.72 | 12 | 404881 | 7173 | 79332322 |
Neuropathy peripheral | 11.12 | 9.72 | 595 | 404298 | 140710 | 79198785 |
Partner stress | 11.10 | 9.72 | 11 | 404882 | 329 | 79339166 |
Blood creatine phosphokinase | 11.07 | 9.72 | 8 | 404885 | 153 | 79339342 |
Azotaemia | 11.06 | 9.72 | 76 | 404817 | 8200 | 79331295 |
Psychological trauma | 11.05 | 9.72 | 23 | 404870 | 1383 | 79338112 |
Vulvovaginal burning sensation | 11.05 | 9.72 | 25 | 404868 | 1592 | 79337903 |
Throat irritation | 11.02 | 9.72 | 144 | 404749 | 40802 | 79298693 |
Basal cell carcinoma | 11.02 | 9.72 | 258 | 404635 | 37117 | 79302378 |
Thalamic infarction | 11.00 | 9.72 | 22 | 404871 | 1285 | 79338210 |
Drug monitoring procedure not performed | 11.00 | 9.72 | 19 | 404874 | 992 | 79338503 |
Renal cell carcinoma recurrent | 11.00 | 9.72 | 4 | 404889 | 15 | 79339480 |
Hyperprolactinaemia | 10.95 | 9.72 | 5 | 404888 | 4671 | 79334824 |
Varicose vein | 10.94 | 9.72 | 48 | 404845 | 4371 | 79335124 |
Gastritis haemorrhagic | 10.92 | 9.72 | 34 | 404859 | 2623 | 79336872 |
Articular calcification | 10.90 | 9.72 | 9 | 404884 | 211 | 79339284 |
Portal hypertension | 10.88 | 9.72 | 12 | 404881 | 7096 | 79332399 |
Multiple allergies | 10.86 | 9.72 | 23 | 404870 | 10437 | 79329058 |
Hepatic enzyme decreased | 10.85 | 9.72 | 8 | 404885 | 158 | 79339337 |
Pelvic mass | 10.85 | 9.72 | 21 | 404872 | 1198 | 79338297 |
Blood urine present | 10.83 | 9.72 | 160 | 404733 | 21137 | 79318358 |
Lichen planus | 10.82 | 9.72 | 35 | 404858 | 2756 | 79336739 |
Walking aid user | 10.80 | 9.72 | 22 | 404871 | 10126 | 79329369 |
Multiple endocrine neoplasia | 10.80 | 9.72 | 3 | 404890 | 3 | 79339492 |
Calculus prostatic | 10.80 | 9.72 | 3 | 404890 | 3 | 79339492 |
Throat lesion | 10.79 | 9.72 | 12 | 404881 | 411 | 79339084 |
Daydreaming | 10.77 | 9.72 | 18 | 404875 | 915 | 79338580 |
Androgenetic alopecia | 10.76 | 9.72 | 8 | 404885 | 160 | 79339335 |
Vein discolouration | 10.70 | 9.72 | 11 | 404882 | 344 | 79339151 |
Product used for unknown indication | 10.69 | 9.72 | 24 | 404869 | 1520 | 79337975 |
Skin toxicity | 10.69 | 9.72 | 16 | 404877 | 8298 | 79331197 |
Oedema | 10.67 | 9.72 | 497 | 404396 | 119083 | 79220412 |
Stent placement | 10.64 | 9.72 | 63 | 404830 | 6457 | 79333038 |
Raynaud's phenomenon | 10.64 | 9.72 | 19 | 404874 | 1019 | 79338476 |
Overdose | 10.63 | 9.72 | 798 | 404095 | 183408 | 79156087 |
Premature baby | 10.63 | 9.72 | 3 | 404890 | 3777 | 79335718 |
Polycystic ovaries | 10.62 | 9.72 | 3 | 404890 | 3776 | 79335719 |
Pulmonary toxicity | 10.62 | 9.72 | 32 | 404861 | 12882 | 79326613 |
Red blood cell count decreased | 10.59 | 9.72 | 217 | 404676 | 57296 | 79282199 |
Eructation | 10.59 | 9.72 | 93 | 404800 | 10816 | 79328679 |
Injection site warmth | 10.59 | 9.72 | 39 | 404854 | 14768 | 79324727 |
Breast atrophy | 10.56 | 9.72 | 6 | 404887 | 74 | 79339421 |
Herbal interaction | 10.52 | 9.72 | 13 | 404880 | 499 | 79338996 |
Acute myeloid leukaemia | 10.52 | 9.72 | 103 | 404790 | 30782 | 79308713 |
Alanine aminotransferase abnormal | 10.52 | 9.72 | 18 | 404875 | 8849 | 79330646 |
Hypoaesthesia | 10.51 | 9.72 | 776 | 404117 | 178576 | 79160919 |
Tongue biting | 10.50 | 9.72 | 29 | 404864 | 2092 | 79337403 |
Peripheral ischaemia | 10.44 | 9.72 | 83 | 404810 | 9374 | 79330121 |
Lymph node palpable | 10.43 | 9.72 | 8 | 404885 | 168 | 79339327 |
Myocarditis | 10.43 | 9.72 | 66 | 404827 | 21667 | 79317828 |
Bone pain | 10.36 | 9.72 | 210 | 404683 | 55532 | 79283963 |
Coagulation time prolonged | 10.32 | 9.72 | 32 | 404861 | 2463 | 79337032 |
Tongue dry | 10.32 | 9.72 | 20 | 404873 | 1142 | 79338353 |
Meibomianitis | 10.29 | 9.72 | 6 | 404887 | 78 | 79339417 |
Gallbladder enlargement | 10.29 | 9.72 | 25 | 404868 | 1668 | 79337827 |
Pancreatic neoplasm | 10.29 | 9.72 | 23 | 404870 | 1453 | 79338042 |
Occult blood positive | 10.28 | 9.72 | 65 | 404828 | 6818 | 79332677 |
Cerebellar ischaemia | 10.28 | 9.72 | 9 | 404884 | 229 | 79339266 |
Adenocarcinoma pancreas | 10.26 | 9.72 | 28 | 404865 | 2005 | 79337490 |
Motor neurone disease | 10.25 | 9.72 | 14 | 404879 | 594 | 79338901 |
Alcohol interaction | 10.25 | 9.72 | 6 | 404887 | 4868 | 79334627 |
Product substitution issue | 10.23 | 9.72 | 152 | 404741 | 20104 | 79319391 |
Pancreatitis chronic | 10.22 | 9.72 | 44 | 404849 | 3975 | 79335520 |
Rotator cuff syndrome | 10.18 | 9.72 | 113 | 404780 | 13982 | 79325513 |
Product storage error | 10.17 | 9.72 | 45 | 404848 | 16181 | 79323314 |
Drug level above therapeutic | 10.08 | 9.72 | 18 | 404875 | 8705 | 79330790 |
Joint injury | 10.06 | 9.72 | 106 | 404787 | 31229 | 79308266 |
Carcinoma in situ of skin | 10.04 | 9.72 | 8 | 404885 | 178 | 79339317 |
Acoustic neuroma | 10.04 | 9.72 | 10 | 404883 | 301 | 79339194 |
PCO2 decreased | 10 | 9.72 | 37 | 404856 | 3117 | 79336378 |
Coordination abnormal | 9.99 | 9.72 | 133 | 404760 | 17179 | 79322316 |
Scleroderma | 9.96 | 9.72 | 8 | 404885 | 5502 | 79333993 |
Social fear | 9.93 | 9.72 | 4 | 404889 | 21 | 79339474 |
Activated partial thromboplastin time shortened | 9.92 | 9.72 | 17 | 404876 | 882 | 79338613 |
Eyelid infection | 9.87 | 9.72 | 11 | 404882 | 378 | 79339117 |
Myoglobinaemia | 9.86 | 9.72 | 7 | 404886 | 130 | 79339365 |
Peripheral embolism | 9.85 | 9.72 | 27 | 404866 | 1939 | 79337556 |
Gallbladder neoplasm | 9.85 | 9.72 | 6 | 404887 | 85 | 79339410 |
Penile oedema | 9.82 | 9.72 | 10 | 404883 | 309 | 79339186 |
Sarcoidosis | 9.82 | 9.72 | 17 | 404876 | 8318 | 79331177 |
Thrombosis in device | 9.81 | 9.72 | 54 | 404839 | 5388 | 79334107 |
Gastric mucosa erythema | 9.77 | 9.72 | 11 | 404882 | 382 | 79339113 |
Product preparation error | 9.76 | 9.72 | 9 | 404884 | 5784 | 79333711 |
Hyperlactacidaemia | 9.75 | 9.72 | 55 | 404838 | 5540 | 79333955 |
Prostate examination abnormal | 9.74 | 9.72 | 8 | 404885 | 186 | 79339309 |
Renal tubular necrosis | 9.73 | 9.72 | 180 | 404713 | 24859 | 79314636 |
Dental plaque | 9.73 | 9.72 | 6 | 404887 | 87 | 79339408 |
None
Source | Code | Description |
---|---|---|
ATC | A10BH51 | ALIMENTARY TRACT AND METABOLISM DRUGS USED IN DIABETES BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS Dipeptidyl peptidase 4 (DPP-4) inhibitors |
ATC | C10AA01 | CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, PLAIN HMG CoA reductase inhibitors |
ATC | C10BA02 | CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, COMBINATIONS Combinations of various lipid modifying agents |
ATC | C10BA04 | CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, COMBINATIONS Combinations of various lipid modifying agents |
ATC | C10BX01 | CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, COMBINATIONS Lipid modifying agents in combination with other drugs |
ATC | C10BX04 | CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, COMBINATIONS Lipid modifying agents in combination with other drugs |
FDA MoA | N0000000121 | Hydroxymethylglutaryl-CoA Reductase Inhibitors |
FDA EPC | N0000175589 | HMG-CoA Reductase Inhibitor |
CHEBI has role | CHEBI:35664 | hydroxymethylglutaryl-CoA reductase inhibitors |
CHEBI has role | CHEBI:50266 | Prodrugs |
CHEBI has role | CHEBI:77255 | lethal toxin inhibitors |
CHEBI has role | CHEBI:173085 | ferroptosis inducers |
CHEBI has role | CHEBI:176497 | geroprotectors |
MeSH PA | D000924 | Anticholesteremic Agents |
MeSH PA | D000963 | Antimetabolites |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D019161 | Hydroxymethylglutaryl-CoA Reductase Inhibitors |
MeSH PA | D000960 | Hypolipidemic Agents |
MeSH PA | D057847 | Lipid Regulating Agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Hypercholesterolemia | indication | 13644009 | |
Arteriosclerotic vascular disease | indication | 72092001 | |
Hypoalphalipoproteinemia | indication | 190785000 | |
Cerebrovascular accident | indication | 230690007 | |
Familial hypercholesterolemia - homozygous | indication | 238078005 | |
Familial hypercholesterolemia - heterozygous | indication | 238079002 | |
Mixed hyperlipidemia | indication | 267434003 | |
Hypertriglyceridemia | indication | 302870006 | |
Familial type 3 hyperlipoproteinemia | indication | 398796005 | DOID:3145 |
Prevention of Transient Ischemic Attacks | indication | ||
Slow Progression of Coronary Artery Disease | indication | ||
Myocardial Infarction Prevention | indication | ||
Alopecia areata | off-label use | 68225006 | DOID:986 |
Primary Prevention of Coronary Heart Disease | off-label use | ||
Myocardial Reinfarction Prevention | off-label use | ||
Hypophosphatemia | contraindication | 4996001 | |
Alcoholism | contraindication | 7200002 | |
Peptic ulcer | contraindication | 13200003 | DOID:750 |
Myocardial infarction | contraindication | 22298006 | DOID:5844 |
Low blood pressure | contraindication | 45007003 | |
Acute nephropathy | contraindication | 58574008 | |
Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Hyperglycemia | contraindication | 80394007 | DOID:4195 |
Gout | contraindication | 90560007 | DOID:13189 |
Disorder of muscle | contraindication | 129565002 | DOID:423 |
Liver function tests abnormal | contraindication | 166603001 | |
Acute pancreatitis | contraindication | 197456007 | DOID:2913 |
Hemorrhagic cerebral infarction | contraindication | 230706003 | |
Arterial hemorrhage | contraindication | 234003006 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Rhabdomyolysis | contraindication | 240131006 | |
Pregnancy, function | contraindication | 289908002 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Surgical procedure | contraindication | 387713003 | |
Acute coronary syndrome | contraindication | 394659003 | |
Breastfeeding (mother) | contraindication | 413712001 | |
Disorder of coronary artery | contraindication | 414024009 | |
Myopathy related to SLCO1B1 Gene Variant | contraindication | ||
SLCO1B1 Gene Variant for OATP1B1 Transporter Affecting Hepatic Clearance | contraindication |
None
None
None
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | JUVISYNC | MERCK SHARP DOHME | N202343 | Oct. 7, 2011 | DISCN | TABLET | ORAL | 7326708 | April 11, 2026 | METHOD OF TREATING TYPE 2 DIABETES MELLITUS IN PATIENTS FOR WHOM TREATMENT WITH BOTH SITAGLIPTIN AND SIMVASTATIN IS APPROPRIATE |
10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | JUVISYNC | MERCK SHARP DOHME | N202343 | Sept. 18, 2012 | DISCN | TABLET | ORAL | 7326708 | April 11, 2026 | METHOD OF TREATING TYPE 2 DIABETES MELLITUS IN PATIENTS FOR WHOM TREATMENT WITH BOTH SITAGLIPTIN AND SIMVASTATIN IS APPROPRIATE |
20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | JUVISYNC | MERCK SHARP DOHME | N202343 | Oct. 7, 2011 | DISCN | TABLET | ORAL | 7326708 | April 11, 2026 | METHOD OF TREATING TYPE 2 DIABETES MELLITUS IN PATIENTS FOR WHOM TREATMENT WITH BOTH SITAGLIPTIN AND SIMVASTATIN IS APPROPRIATE |
20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | JUVISYNC | MERCK SHARP DOHME | N202343 | Sept. 18, 2012 | DISCN | TABLET | ORAL | 7326708 | April 11, 2026 | METHOD OF TREATING TYPE 2 DIABETES MELLITUS IN PATIENTS FOR WHOM TREATMENT WITH BOTH SITAGLIPTIN AND SIMVASTATIN IS APPROPRIATE |
40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | JUVISYNC | MERCK SHARP DOHME | N202343 | Oct. 7, 2011 | DISCN | TABLET | ORAL | 7326708 | April 11, 2026 | METHOD OF TREATING TYPE 2 DIABETES MELLITUS IN PATIENTS FOR WHOM TREATMENT WITH BOTH SITAGLIPTIN AND SIMVASTATIN IS APPROPRIATE |
40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** | JUVISYNC | MERCK SHARP DOHME | N202343 | Sept. 18, 2012 | DISCN | TABLET | ORAL | 7326708 | April 11, 2026 | METHOD OF TREATING TYPE 2 DIABETES MELLITUS IN PATIENTS FOR WHOM TREATMENT WITH BOTH SITAGLIPTIN AND SIMVASTATIN IS APPROPRIATE |
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Enzyme | INHIBITOR | IC50 | 7.77 | WOMBAT-PK | CHEMBL | |||
Nuclear receptor subfamily 1 group I member 3 | Nuclear hormone receptor | WOMBAT-PK | |||||||
Nuclear receptor subfamily 4 group A member 2 | Nuclear other | EC50 | 5.29 | CHEMBL | |||||
Acetylcholinesterase | Enzyme | Ki | 5.74 | CHEMBL | |||||
Cholinesterase | Enzyme | Ki | 6.12 | CHEMBL | |||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Enzyme | IC50 | 4.02 | CHEMBL | |||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Enzyme | IC50 | 8.37 | CHEMBL |
ID | Source |
---|---|
4020400 | VUID |
N0000148200 | NUI |
D00434 | KEGG_DRUG |
4020400 | VANDF |
C0074554 | UMLSCUI |
CHEBI:9150 | CHEBI |
CHEMBL1064 | ChEMBL_ID |
D019821 | MESH_DESCRIPTOR_UI |
DB00641 | DRUGBANK_ID |
54454 | PUBCHEM_CID |
2955 | IUPHAR_LIGAND_ID |
6147 | INN_ID |
AGG2FN16EV | UNII |
36567 | RXNORM |
5465 | MMSL |
82969 | MMSL |
d00746 | MMSL |
003621 | NDDF |
387584000 | SNOMEDCT_US |
96304005 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
ZOCOR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0006-0543 | TABLET, FILM COATED | 80 mg | ORAL | NDA | 31 sections |
ZOCOR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0006-0735 | TABLET, FILM COATED | 10 mg | ORAL | NDA | 31 sections |
ZOCOR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0006-0740 | TABLET, FILM COATED | 20 mg | ORAL | NDA | 31 sections |
ZOCOR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0006-0749 | TABLET, FILM COATED | 40 mg | ORAL | NDA | 31 sections |
SIMVASTATIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7992 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 27 sections |
SIMVASTATIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7992 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 27 sections |
SIMVASTATIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7992 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 27 sections |
SIMVASTATIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7993 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 27 sections |
SIMVASTATIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7993 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 27 sections |
SIMVASTATIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7993 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 27 sections |
SIMVASTATIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8056 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 26 sections |
SIMVASTATIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8056 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 26 sections |
Simvastatin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-486 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 25 sections |
Simvastatin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-487 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 25 sections |
simvastatin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-907 | TABLET, FILM COATED | 80 mg | ORAL | ANDA | 27 sections |
simvastatin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-908 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 27 sections |
Simvastatin | Human Prescription Drug Label | 1 | 13107-050 | TABLET, FILM COATED | 5 mg | ORAL | ANDA | 27 sections |
Simvastatin | Human Prescription Drug Label | 1 | 13107-051 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 27 sections |
Simvastatin | Human Prescription Drug Label | 1 | 13107-052 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 27 sections |
Simvastatin | Human Prescription Drug Label | 1 | 13107-053 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 27 sections |
Simvastatin | Human Prescription Drug Label | 1 | 13107-054 | TABLET, FILM COATED | 80 mg | ORAL | ANDA | 27 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-681 | TABLET, FILM COATED | 5 mg | ORAL | ANDA | 29 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-681 | TABLET, FILM COATED | 5 mg | ORAL | ANDA | 29 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-681 | TABLET, FILM COATED | 5 mg | ORAL | ANDA | 29 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-681 | TABLET, FILM COATED | 5 mg | ORAL | ANDA | 29 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-682 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 29 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-682 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 29 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-682 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 29 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-682 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 29 sections |
Simvastatin | Human Prescription Drug Label | 1 | 16714-683 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 29 sections |