seratrodast 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| thromboxane A2 receptor antagonists, antiasthmatics | 2432 | 112665-43-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
has thromboxane A2 & prostaglandin H2 receptor antagonistic action
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | R03DX06 | RESPIRATORY SYSTEM DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES Other systemic drugs for obstructive airway diseases |
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D018712 | Analgesics, Non-Narcotic |
| MeSH PA | D018927 | Anti-Asthmatic Agents |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| MeSH PA | D018501 | Antirheumatic Agents |
| MeSH PA | D006727 | Hormone Antagonists |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D011448 | Prostaglandin Antagonists |
| MeSH PA | D019141 | Respiratory System Agents |
| MeSH PA | D018689 | Sensory System Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 4.85 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Thromboxane A2 receptor | GPCR | IC50 | 8.13 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D01123 | KEGG_DRUG |
| C0050339 | UMLSCUI |
| CHEBI:32126 | CHEBI |
| CHEMBL70972 | ChEMBL_ID |
| DB06739 | DRUGBANK_ID |
| C060230 | MESH_SUPPLEMENTAL_RECORD_UI |
| 2449 | PUBCHEM_CID |
| 7069 | INN_ID |
| 4U58JM421N | UNII |
| 1201970002 | SNOMEDCT_US |
Pharmaceutical products:
None