fenspiride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1163 5053-06-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • fenspiride
  • respiride
  • fenspiride hydrochloride
  • fenspiride HCl
  • decaspiride
  • Molecular weight: 260.34
  • Formula: C15H20N2O2
  • CLOGP: 2.02
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 41.57
  • ALOGS: -1.98
  • ROTB: 3

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 90 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution) 3 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 2.60 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 14 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R03BX01 RESPIRATORY SYSTEM
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
Other drugs for obstructive airway diseases, inhalants
ATC R03DX03 RESPIRATORY SYSTEM
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
Other systemic drugs for obstructive airway diseases
MeSH PA D018927 Anti-Asthmatic Agents
MeSH PA D001993 Bronchodilator Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D019141 Respiratory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.16 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04163 KEGG_DRUG
5053-08-7 SECONDARY_CAS_RN
C0015843 UMLSCUI
CHEBI:94558 CHEBI
CHEMBL576127 ChEMBL_ID
DB08979 DRUGBANK_ID
C084775 MESH_SUPPLEMENTAL_RECORD_UI
3344 PUBCHEM_CID
2577 INN_ID
S983QC7HKM UNII
236281 RXNORM
005567 NDDF
005568 NDDF
712690002 SNOMEDCT_US
712691003 SNOMEDCT_US
CHEMBL1256849 ChEMBL_ID

Pharmaceutical products:

None