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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
propyphenazone 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
anti-inflammatory analgesics, phenylbutazone derivatives
2309
479-92-5
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
yoshipyrin
propyphenazone
isopropchin
isopropylantipyrin
isopropylantipyrine
isopropylphenazone
isopropyrine
propyfenazone
propifenazone
Molecular weight: 230.31
Formula: C14H18N2O
CLOGP: 1.34
LIPINSKI: 0
HAC: 3
HDO: 0
TPSA: 23.55
ALOGS: -1.40
ROTB: 2
Drug dosage:
Dose
Unit
Route
3
g
R
3
g
O
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
N02BB04
NERVOUS SYSTEM
ANALGESICS
OTHER ANALGESICS AND ANTIPYRETICS
Pyrazolones
ATC
N02BB54
NERVOUS SYSTEM
ANALGESICS
OTHER ANALGESICS AND ANTIPYRETICS
Pyrazolones
ATC
N02BB74
NERVOUS SYSTEM
ANALGESICS
OTHER ANALGESICS AND ANTIPYRETICS
Pyrazolones
CHEBI has role
CHEBI:35475
non-steroidal anti-inflammatory agent
CHEBI has role
CHEBI:49110
peripheral nervous system drugs
MeSH PA
D000700
Analgesics
MeSH PA
D018712
Analgesics, Non-Narcotic
MeSH PA
D000893
Anti-Inflammatory Agents
MeSH PA
D000894
Anti-Inflammatory Agents, Non-Steroidal
MeSH PA
D018501
Antirheumatic Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Transient receptor potential cation channel subfamily A member 1
Ion channel
O75762
TRPA1_HUMAN
BLOCKER
IC50
4.48
SCIENTIFIC LITERATURE
SCIENTIFIC LITERATURE
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External reference:
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entries
Search:
ID
Source
004365
NDDF
2848
INN_ID
34710
RXNORM
3778
PUBCHEM_CID
699188007
SNOMEDCT_US
C0072245
UMLSCUI
C009077
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:135538
CHEBI
CHEMBL28318
ChEMBL_ID
D01380
KEGG_DRUG
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
GEWORIN
HUMAN OTC DRUG LABEL
3
72689-0019
TABLET
150 mg
ORAL
OTC monograph not final
7 sections
GEWORIN
HUMAN OTC DRUG LABEL
2
72988-0036
TABLET
150 mg
ORAL
unapproved drug other
7 sections
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propyphenazone