Stem definition | Drug id | CAS RN |
---|---|---|
psychoactive | 1982 | 132539-06-1 |
Dose | Unit | Route |
---|---|---|
10 | mg | O |
10 | mg | P |
10 | mg | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.01 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 7 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 0.69 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 60 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
Sept. 30, 1996 | FDA | LILLY |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Neuroleptic malignant syndrome | 1206.55 | 10.75 | 517 | 80036 | 10605 | 46594904 |
Intentional overdose | 832.72 | 10.75 | 772 | 79781 | 64172 | 46541337 |
Suicide attempt | 821.77 | 10.75 | 713 | 79840 | 54323 | 46551186 |
Sedation | 719.41 | 10.75 | 464 | 80089 | 22446 | 46583063 |
Psychotic disorder | 665.90 | 10.75 | 440 | 80113 | 22181 | 46583328 |
Schizophrenia | 642.59 | 10.75 | 308 | 80245 | 8260 | 46597249 |
Intentional self-injury | 604.32 | 10.75 | 425 | 80128 | 23741 | 46581768 |
Extrapyramidal disorder | 508.20 | 10.75 | 288 | 80265 | 10980 | 46594529 |
Akathisia | 505.72 | 10.75 | 253 | 80300 | 7461 | 46598048 |
Electrocardiogram QT prolonged | 488.44 | 10.75 | 519 | 80034 | 50806 | 46554703 |
Sopor | 468.68 | 10.75 | 337 | 80216 | 19491 | 46586018 |
Agitation | 464.17 | 10.75 | 524 | 80029 | 54891 | 46550618 |
Overdose | 458.21 | 10.75 | 710 | 79843 | 101269 | 46504240 |
Toxicity to various agents | 425.63 | 10.75 | 1049 | 79504 | 210717 | 46394792 |
Weight increased | 415.66 | 10.75 | 892 | 79661 | 163581 | 46441928 |
Dystonia | 398.31 | 10.75 | 246 | 80307 | 11011 | 46594498 |
Drug interaction | 395.35 | 10.75 | 994 | 79559 | 202100 | 46403409 |
Delusion | 371.92 | 10.75 | 235 | 80318 | 10953 | 46594556 |
Mania | 366.02 | 10.75 | 230 | 80323 | 10616 | 46594893 |
Rheumatoid arthritis | 364.57 | 10.75 | 11 | 80542 | 240204 | 46365305 |
Arthralgia | 354.39 | 10.75 | 96 | 80457 | 364507 | 46241002 |
Catatonia | 349.81 | 10.75 | 157 | 80396 | 3605 | 46601904 |
Drug abuse | 347.49 | 10.75 | 485 | 80068 | 62923 | 46542586 |
Post-injection delirium sedation syndrome | 345.10 | 10.75 | 67 | 80486 | 16 | 46605493 |
Parkinsonism | 341.89 | 10.75 | 197 | 80356 | 7751 | 46597758 |
Blood prolactin abnormal | 341.05 | 10.75 | 115 | 80438 | 1174 | 46604335 |
Hyperprolactinaemia | 333.37 | 10.75 | 141 | 80412 | 2791 | 46602718 |
Diabetes mellitus | 329.71 | 10.75 | 419 | 80134 | 49646 | 46555863 |
Somnolence | 318.98 | 10.75 | 780 | 79773 | 155741 | 46449768 |
Hallucination, auditory | 308.61 | 10.75 | 206 | 80347 | 10550 | 46594959 |
Sexual dysfunction | 305.00 | 10.75 | 125 | 80428 | 2278 | 46603231 |
Anosognosia | 304.53 | 10.75 | 108 | 80445 | 1297 | 46604212 |
Coma | 276.93 | 10.75 | 417 | 80136 | 57932 | 46547577 |
Pain | 270.02 | 10.75 | 256 | 80297 | 476692 | 46128817 |
Disturbance in social behaviour | 268.27 | 10.75 | 104 | 80449 | 1627 | 46603882 |
Metabolic disorder | 263.20 | 10.75 | 136 | 80417 | 4296 | 46601213 |
Tardive dyskinesia | 262.16 | 10.75 | 163 | 80390 | 7380 | 46598129 |
Hypothermia | 251.69 | 10.75 | 191 | 80362 | 11992 | 46593517 |
Completed suicide | 239.61 | 10.75 | 671 | 79882 | 145249 | 46460260 |
Dyskinesia | 237.73 | 10.75 | 271 | 80282 | 28654 | 46576855 |
Suicidal ideation | 224.71 | 10.75 | 372 | 80181 | 56010 | 46549499 |
Headache | 222.46 | 10.75 | 301 | 80252 | 478051 | 46127458 |
Aggression | 216.18 | 10.75 | 230 | 80323 | 22514 | 46582995 |
Muscle rigidity | 214.28 | 10.75 | 160 | 80393 | 9801 | 46595708 |
Salivary hypersecretion | 210.75 | 10.75 | 134 | 80419 | 6311 | 46599198 |
Depressed level of consciousness | 210.24 | 10.75 | 329 | 80224 | 47240 | 46558269 |
Diarrhoea | 208.03 | 10.75 | 408 | 80145 | 559194 | 46046315 |
Psychomotor hyperactivity | 203.65 | 10.75 | 153 | 80400 | 9460 | 46596049 |
Confusional state | 200.46 | 10.75 | 669 | 79884 | 159223 | 46446286 |
Metabolic syndrome | 198.47 | 10.75 | 77 | 80476 | 1207 | 46604302 |
Delirium | 196.76 | 10.75 | 280 | 80273 | 36948 | 46568561 |
Pleurothotonus | 194.88 | 10.75 | 74 | 80479 | 1091 | 46604418 |
Hypomania | 194.69 | 10.75 | 111 | 80442 | 4277 | 46601232 |
Fatigue | 190.20 | 10.75 | 488 | 80065 | 608209 | 45997300 |
Restlessness | 189.50 | 10.75 | 227 | 80326 | 25297 | 46580212 |
Gestational diabetes | 187.44 | 10.75 | 130 | 80423 | 7089 | 46598420 |
Blood prolactin increased | 185.85 | 10.75 | 95 | 80458 | 2932 | 46602577 |
Dyspnoea | 184.56 | 10.75 | 384 | 80169 | 515164 | 46090345 |
Prescribed overdose | 171.26 | 10.75 | 143 | 80410 | 10306 | 46595203 |
Hallucination | 169.48 | 10.75 | 307 | 80246 | 49644 | 46555865 |
Personality change | 168.64 | 10.75 | 108 | 80445 | 5150 | 46600359 |
Drug hypersensitivity | 165.09 | 10.75 | 109 | 80444 | 243716 | 46361793 |
Tachycardia | 160.31 | 10.75 | 455 | 80098 | 99167 | 46506342 |
Persecutory delusion | 159.23 | 10.75 | 81 | 80472 | 2474 | 46603035 |
Exposure during pregnancy | 152.03 | 10.75 | 471 | 80082 | 107741 | 46497768 |
Miosis | 150.07 | 10.75 | 110 | 80443 | 6547 | 46598962 |
Paranoia | 147.30 | 10.75 | 132 | 80421 | 10465 | 46595044 |
Pain in extremity | 146.94 | 10.75 | 138 | 80415 | 258542 | 46346967 |
Abnormal behaviour | 146.10 | 10.75 | 181 | 80372 | 20877 | 46584632 |
Sinusitis | 140.03 | 10.75 | 27 | 80526 | 129741 | 46475768 |
Oculogyric crisis | 139.18 | 10.75 | 59 | 80494 | 1174 | 46604335 |
Back pain | 135.37 | 10.75 | 99 | 80454 | 209940 | 46395569 |
Pruritus | 133.31 | 10.75 | 133 | 80420 | 242219 | 46363290 |
Injection site pain | 132.39 | 10.75 | 15 | 80538 | 107137 | 46498372 |
Rash | 132.02 | 10.75 | 260 | 80293 | 356252 | 46249257 |
Type 2 diabetes mellitus | 122.37 | 10.75 | 161 | 80392 | 19714 | 46585795 |
Social avoidant behaviour | 121.10 | 10.75 | 70 | 80483 | 2769 | 46602740 |
Treatment noncompliance | 120.85 | 10.75 | 198 | 80355 | 29533 | 46575976 |
Schizoaffective disorder | 120.51 | 10.75 | 56 | 80497 | 1396 | 46604113 |
Joint swelling | 119.60 | 10.75 | 69 | 80484 | 166004 | 46439505 |
Bipolar disorder | 119.23 | 10.75 | 99 | 80454 | 7078 | 46598431 |
Abdominal discomfort | 118.93 | 10.75 | 56 | 80497 | 151109 | 46454400 |
Nausea | 116.87 | 10.75 | 703 | 79850 | 686751 | 45918758 |
Galactorrhoea | 116.86 | 10.75 | 76 | 80477 | 3721 | 46601788 |
Dysarthria | 114.10 | 10.75 | 220 | 80333 | 37278 | 46568231 |
Blood creatine phosphokinase increased | 111.83 | 10.75 | 184 | 80369 | 27540 | 46577969 |
Peripheral swelling | 109.16 | 10.75 | 69 | 80484 | 158002 | 46447507 |
Cough | 108.56 | 10.75 | 143 | 80410 | 230106 | 46375403 |
Antipsychotic drug level increased | 108.44 | 10.75 | 68 | 80485 | 3124 | 46602385 |
Hypersensitivity | 107.46 | 10.75 | 63 | 80490 | 150258 | 46455251 |
Infusion related reaction | 107.20 | 10.75 | 22 | 80531 | 101186 | 46504323 |
Arthropathy | 106.80 | 10.75 | 11 | 80542 | 84689 | 46520820 |
Blood triglycerides increased | 106.40 | 10.75 | 116 | 80437 | 11667 | 46593842 |
Tremor | 106.27 | 10.75 | 438 | 80115 | 115201 | 46490308 |
Nasopharyngitis | 101.25 | 10.75 | 71 | 80482 | 153927 | 46451582 |
Pneumonia aspiration | 98.09 | 10.75 | 187 | 80366 | 31418 | 46574091 |
Psychiatric decompensation | 95.35 | 10.75 | 44 | 80509 | 1079 | 46604430 |
Antipsychotic drug level above therapeutic | 93.02 | 10.75 | 41 | 80512 | 900 | 46604609 |
Alopecia | 92.88 | 10.75 | 86 | 80467 | 162328 | 46443181 |
Urticaria | 92.21 | 10.75 | 44 | 80509 | 117848 | 46487661 |
Product dose omission issue | 90.86 | 10.75 | 94 | 80459 | 168426 | 46437083 |
Injection site erythema | 90.47 | 10.75 | 11 | 80542 | 74416 | 46531093 |
Diabetic coma | 90.39 | 10.75 | 38 | 80515 | 740 | 46604769 |
Disorientation | 90.36 | 10.75 | 198 | 80355 | 36720 | 46568789 |
Orthostatic hypertension | 89.64 | 10.75 | 27 | 80526 | 184 | 46605325 |
Rhabdomyolysis | 89.54 | 10.75 | 213 | 80340 | 41696 | 46563813 |
Chest discomfort | 88.87 | 10.75 | 23 | 80530 | 90246 | 46515263 |
Swelling | 86.43 | 10.75 | 54 | 80499 | 124457 | 46481052 |
Leukopenia | 84.60 | 10.75 | 285 | 80268 | 68058 | 46537451 |
Obesity | 84.25 | 10.75 | 113 | 80440 | 14093 | 46591416 |
Respiratory depression | 84.16 | 10.75 | 102 | 80451 | 11498 | 46594011 |
Granulocytopenia | 84.00 | 10.75 | 71 | 80482 | 5202 | 46600307 |
Contraindicated product administered | 83.38 | 10.75 | 18 | 80535 | 79929 | 46525580 |
Psychiatric symptom | 83.07 | 10.75 | 66 | 80487 | 4431 | 46601078 |
Bradyphrenia | 81.47 | 10.75 | 75 | 80478 | 6155 | 46599354 |
Arthritis | 81.46 | 10.75 | 17 | 80536 | 77299 | 46528210 |
Posture abnormal | 80.35 | 10.75 | 49 | 80504 | 2141 | 46603368 |
Amenorrhoea | 79.32 | 10.75 | 87 | 80466 | 8808 | 46596701 |
Drug intolerance | 79.28 | 10.75 | 82 | 80471 | 146967 | 46458542 |
Anxiety | 78.40 | 10.75 | 560 | 79993 | 181397 | 46424112 |
Neutropenia | 77.68 | 10.75 | 467 | 80086 | 142737 | 46462772 |
Apathy | 75.31 | 10.75 | 77 | 80476 | 7191 | 46598318 |
Obsessive-compulsive disorder | 74.45 | 10.75 | 54 | 80499 | 3161 | 46602348 |
Blood glucose increased | 74.36 | 10.75 | 283 | 80270 | 71730 | 46533779 |
Generalised tonic-clonic seizure | 72.76 | 10.75 | 151 | 80402 | 26971 | 46578538 |
Mental disorder | 72.45 | 10.75 | 135 | 80418 | 22290 | 46583219 |
Psoriasis | 71.89 | 10.75 | 23 | 80530 | 78581 | 46526928 |
Polydipsia | 71.25 | 10.75 | 53 | 80500 | 3226 | 46602283 |
Jaundice cholestatic | 70.59 | 10.75 | 63 | 80490 | 4966 | 46600543 |
Increased appetite | 70.21 | 10.75 | 80 | 80473 | 8447 | 46597062 |
Serotonin syndrome | 67.51 | 10.75 | 137 | 80416 | 24083 | 46581426 |
Cogwheel rigidity | 66.93 | 10.75 | 38 | 80515 | 1452 | 46604057 |
Myalgia | 63.71 | 10.75 | 71 | 80482 | 123017 | 46482492 |
Negativism | 62.34 | 10.75 | 24 | 80529 | 368 | 46605141 |
Pulmonary embolism | 61.35 | 10.75 | 358 | 80195 | 108227 | 46497282 |
Influenza | 60.18 | 10.75 | 40 | 80513 | 89230 | 46516279 |
Thinking abnormal | 59.63 | 10.75 | 79 | 80474 | 9735 | 46595774 |
Drug level increased | 59.55 | 10.75 | 111 | 80442 | 18330 | 46587179 |
Osteoarthritis | 58.79 | 10.75 | 17 | 80536 | 62008 | 46543501 |
Treatment failure | 58.44 | 10.75 | 45 | 80508 | 93042 | 46512467 |
Systemic lupus erythematosus | 57.98 | 10.75 | 20 | 80533 | 65160 | 46540349 |
Malaise | 57.39 | 10.75 | 336 | 80217 | 330896 | 46274613 |
Acute psychosis | 56.76 | 10.75 | 38 | 80515 | 1954 | 46603555 |
Injection site pruritus | 56.21 | 10.75 | 3 | 80550 | 39740 | 46565769 |
Mental impairment | 56.17 | 10.75 | 87 | 80466 | 12369 | 46593140 |
Camptocormia | 55.82 | 10.75 | 19 | 80534 | 200 | 46605309 |
Mutism | 55.30 | 10.75 | 32 | 80521 | 1268 | 46604241 |
Anaphylactic reaction | 55.28 | 10.75 | 12 | 80541 | 53100 | 46552409 |
Dyslipidaemia | 54.35 | 10.75 | 57 | 80496 | 5483 | 46600026 |
Cardio-respiratory arrest | 54.33 | 10.75 | 226 | 80327 | 59643 | 46545866 |
Seizure | 54.27 | 10.75 | 381 | 80172 | 122673 | 46482836 |
Herpes zoster | 53.56 | 10.75 | 25 | 80528 | 67847 | 46537662 |
Screaming | 52.96 | 10.75 | 44 | 80509 | 3147 | 46602362 |
Myocarditis | 52.83 | 10.75 | 66 | 80487 | 7673 | 46597836 |
Hyperglycaemia | 52.30 | 10.75 | 156 | 80397 | 34915 | 46570594 |
Obsessive thoughts | 52.05 | 10.75 | 23 | 80530 | 508 | 46605001 |
Hallucinations, mixed | 51.62 | 10.75 | 47 | 80506 | 3802 | 46601707 |
Obsessive-compulsive symptom | 51.56 | 10.75 | 12 | 80541 | 23 | 46605486 |
Psychotic symptom | 51.38 | 10.75 | 27 | 80526 | 883 | 46604626 |
Poisoning | 51.28 | 10.75 | 89 | 80464 | 13905 | 46591604 |
Speech disorder | 51.24 | 10.75 | 158 | 80395 | 36009 | 46569500 |
Psychomotor retardation | 50.41 | 10.75 | 43 | 80510 | 3190 | 46602319 |
Bone pain | 50.03 | 10.75 | 10 | 80543 | 46880 | 46558629 |
Sinus tachycardia | 49.48 | 10.75 | 113 | 80440 | 21536 | 46583973 |
Irritability | 49.23 | 10.75 | 135 | 80418 | 28811 | 46576698 |
Chest pain | 48.31 | 10.75 | 150 | 80403 | 176174 | 46429335 |
Hyponatraemia | 47.79 | 10.75 | 319 | 80234 | 101013 | 46504496 |
Neuropathy peripheral | 47.49 | 10.75 | 52 | 80501 | 90841 | 46514668 |
Asthma | 47.14 | 10.75 | 53 | 80500 | 91489 | 46514020 |
Depression | 46.42 | 10.75 | 473 | 80080 | 169631 | 46435878 |
Wheezing | 46.42 | 10.75 | 17 | 80536 | 53369 | 46552140 |
Infection | 46.27 | 10.75 | 101 | 80452 | 133491 | 46472018 |
Somatic symptom disorder of pregnancy | 45.79 | 10.75 | 14 | 80539 | 101 | 46605408 |
Urinary retention | 45.78 | 10.75 | 123 | 80430 | 25938 | 46579571 |
Injection site reaction | 45.56 | 10.75 | 13 | 80540 | 47836 | 46557673 |
Hyperammonaemic encephalopathy | 45.23 | 10.75 | 33 | 80520 | 1949 | 46603560 |
Abdominal pain | 44.95 | 10.75 | 224 | 80329 | 229807 | 46375702 |
Hyperthermia | 44.87 | 10.75 | 62 | 80491 | 7952 | 46597557 |
Hypoaesthesia | 44.44 | 10.75 | 86 | 80467 | 118783 | 46486726 |
Trimethylaminuria | 44.40 | 10.75 | 15 | 80538 | 154 | 46605355 |
Logorrhoea | 44.38 | 10.75 | 35 | 80518 | 2324 | 46603185 |
Hyperphagia | 44.20 | 10.75 | 30 | 80523 | 1578 | 46603931 |
Diet refusal | 44.00 | 10.75 | 22 | 80531 | 647 | 46604862 |
Altered state of consciousness | 43.87 | 10.75 | 113 | 80440 | 23235 | 46582274 |
Flushing | 43.48 | 10.75 | 29 | 80524 | 64585 | 46540924 |
Stupor | 43.38 | 10.75 | 41 | 80512 | 3479 | 46602030 |
Abdominal pain upper | 43.14 | 10.75 | 119 | 80434 | 145186 | 46460323 |
Brain stem thrombosis | 42.91 | 10.75 | 8 | 80545 | 0 | 46605509 |
Respiratory arrest | 42.69 | 10.75 | 142 | 80411 | 33674 | 46571835 |
Glossodynia | 42.35 | 10.75 | 12 | 80541 | 44361 | 46561148 |
Unresponsive to stimuli | 42.31 | 10.75 | 137 | 80416 | 32037 | 46573472 |
Symptom recurrence | 41.57 | 10.75 | 18 | 80535 | 378 | 46605131 |
Disturbance in attention | 41.16 | 10.75 | 134 | 80419 | 31426 | 46574083 |
Mydriasis | 41.15 | 10.75 | 69 | 80484 | 10484 | 46595025 |
Alanine aminotransferase increased | 40.83 | 10.75 | 277 | 80276 | 88174 | 46517335 |
Nasal congestion | 40.70 | 10.75 | 16 | 80537 | 48097 | 46557412 |
Bipolar I disorder | 40.50 | 10.75 | 28 | 80525 | 1518 | 46603991 |
White blood cell count increased | 40.17 | 10.75 | 167 | 80386 | 44052 | 46561457 |
Neck pain | 39.73 | 10.75 | 23 | 80530 | 55283 | 46550226 |
Delusion of reference | 39.69 | 10.75 | 12 | 80541 | 83 | 46605426 |
Osteonecrosis of jaw | 39.63 | 10.75 | 6 | 80547 | 34396 | 46571113 |
Coma scale abnormal | 39.58 | 10.75 | 46 | 80507 | 4960 | 46600549 |
Homicide | 39.51 | 10.75 | 18 | 80535 | 428 | 46605081 |
Self esteem decreased | 39.16 | 10.75 | 19 | 80534 | 523 | 46604986 |
Musculoskeletal pain | 39.03 | 10.75 | 38 | 80515 | 70090 | 46535419 |
Depressive symptom | 38.76 | 10.75 | 35 | 80518 | 2801 | 46602708 |
Loss of consciousness | 38.65 | 10.75 | 319 | 80234 | 107919 | 46497590 |
Embolism venous | 38.39 | 10.75 | 33 | 80520 | 2474 | 46603035 |
Psoriatic arthropathy | 38.31 | 10.75 | 8 | 80545 | 36371 | 46569138 |
Hepatocellular injury | 38.19 | 10.75 | 125 | 80428 | 29397 | 46576112 |
Insurance issue | 36.99 | 10.75 | 28 | 80525 | 1750 | 46603759 |
Drooling | 36.94 | 10.75 | 36 | 80517 | 3173 | 46602336 |
Osteoporosis | 36.91 | 10.75 | 12 | 80541 | 40596 | 46564913 |
Self-injurious ideation | 36.70 | 10.75 | 31 | 80522 | 2269 | 46603240 |
Erythema | 36.67 | 10.75 | 125 | 80428 | 142695 | 46462814 |
Injection site swelling | 36.51 | 10.75 | 12 | 80541 | 40315 | 46565194 |
Cognitive disorder | 36.45 | 10.75 | 143 | 80410 | 36740 | 46568769 |
Device expulsion | 36.25 | 10.75 | 3 | 80550 | 27539 | 46577970 |
Therapeutic product effect decreased | 36.16 | 10.75 | 54 | 80499 | 82547 | 46522962 |
Dyspnoea exertional | 36.00 | 10.75 | 21 | 80532 | 50268 | 46555241 |
Oropharyngeal pain | 35.98 | 10.75 | 45 | 80508 | 74123 | 46531386 |
Cor pulmonale acute | 35.77 | 10.75 | 16 | 80537 | 364 | 46605145 |
Muscle spasms | 35.67 | 10.75 | 102 | 80451 | 123011 | 46482498 |
Torsade de pointes | 35.36 | 10.75 | 70 | 80483 | 12084 | 46593425 |
Cardiac arrest | 35.32 | 10.75 | 272 | 80281 | 90127 | 46515382 |
Asthenia | 34.78 | 10.75 | 356 | 80197 | 310719 | 46294790 |
Stomatitis | 34.66 | 10.75 | 40 | 80513 | 68257 | 46537252 |
Illusion | 34.63 | 10.75 | 22 | 80531 | 1034 | 46604475 |
Psychotic disorder due to a general medical condition | 34.46 | 10.75 | 13 | 80540 | 188 | 46605321 |
Neutrophil count increased | 34.36 | 10.75 | 76 | 80477 | 14177 | 46591332 |
Disease progression | 34.17 | 10.75 | 66 | 80487 | 91234 | 46514275 |
Head banging | 34.10 | 10.75 | 16 | 80537 | 408 | 46605101 |
Megacolon | 33.79 | 10.75 | 26 | 80527 | 1665 | 46603844 |
Refusal of treatment by patient | 33.53 | 10.75 | 44 | 80509 | 5371 | 46600138 |
Mobility decreased | 33.53 | 10.75 | 33 | 80520 | 60561 | 46544948 |
Paraesthesia | 33.51 | 10.75 | 98 | 80455 | 117339 | 46488170 |
Neutrophil count decreased | 33.37 | 10.75 | 156 | 80397 | 43270 | 46562239 |
Product use issue | 33.22 | 10.75 | 71 | 80482 | 94573 | 46510936 |
Chills | 32.91 | 10.75 | 73 | 80480 | 95959 | 46509550 |
Hot flush | 32.85 | 10.75 | 17 | 80536 | 43500 | 46562009 |
Affective disorder | 32.77 | 10.75 | 41 | 80512 | 4774 | 46600735 |
Anaemia | 32.74 | 10.75 | 283 | 80270 | 255496 | 46350013 |
Burning sensation | 32.57 | 10.75 | 18 | 80535 | 44393 | 46561116 |
Electrocardiogram T wave inversion | 32.41 | 10.75 | 35 | 80518 | 3481 | 46602028 |
Myoclonic epilepsy | 32.20 | 10.75 | 20 | 80533 | 903 | 46604606 |
Gamma-glutamyltransferase increased | 32.13 | 10.75 | 124 | 80429 | 31616 | 46573893 |
Hypernatraemia | 32.12 | 10.75 | 47 | 80506 | 6354 | 46599155 |
White blood cell count decreased | 32.00 | 10.75 | 315 | 80238 | 111916 | 46493593 |
Hypokinesia | 31.49 | 10.75 | 64 | 80489 | 11258 | 46594251 |
Interstitial lung disease | 31.47 | 10.75 | 28 | 80525 | 53921 | 46551588 |
Cardiac failure congestive | 31.23 | 10.75 | 70 | 80483 | 91680 | 46513829 |
Blood cholesterol increased | 30.93 | 10.75 | 144 | 80409 | 39869 | 46565640 |
Atrial fibrillation | 30.61 | 10.75 | 85 | 80468 | 103505 | 46502004 |
Electroencephalogram abnormal | 30.53 | 10.75 | 35 | 80518 | 3719 | 46601790 |
Upper respiratory tract infection | 30.37 | 10.75 | 39 | 80514 | 63517 | 46541992 |
Oromandibular dystonia | 30.32 | 10.75 | 15 | 80538 | 431 | 46605078 |
Diabetic ketoacidosis | 30.04 | 10.75 | 84 | 80469 | 18126 | 46587383 |
Impaired healing | 29.82 | 10.75 | 13 | 80540 | 36730 | 46568779 |
Dyspepsia | 29.74 | 10.75 | 45 | 80508 | 68427 | 46537082 |
Multiple sclerosis relapse | 29.58 | 10.75 | 18 | 80535 | 42107 | 46563402 |
Waxy flexibility | 29.57 | 10.75 | 10 | 80543 | 103 | 46605406 |
Abnormal clotting factor | 29.40 | 10.75 | 10 | 80543 | 105 | 46605404 |
Substance abuse | 29.19 | 10.75 | 36 | 80517 | 4131 | 46601378 |
Impulse-control disorder | 29.07 | 10.75 | 17 | 80536 | 687 | 46604822 |
Weight decreased | 28.91 | 10.75 | 229 | 80324 | 210620 | 46394889 |
Feeling guilty | 28.90 | 10.75 | 15 | 80538 | 478 | 46605031 |
Depressed mood | 28.83 | 10.75 | 124 | 80429 | 33195 | 46572314 |
Agranulocytosis | 28.75 | 10.75 | 94 | 80459 | 22091 | 46583418 |
Menstruation irregular | 28.54 | 10.75 | 45 | 80508 | 6494 | 46599015 |
Circulatory collapse | 28.36 | 10.75 | 92 | 80461 | 21532 | 46583977 |
Pharyngeal dystonia | 28.04 | 10.75 | 6 | 80547 | 6 | 46605503 |
Polyuria | 27.99 | 10.75 | 47 | 80506 | 7148 | 46598361 |
Sudden death | 27.97 | 10.75 | 55 | 80498 | 9449 | 46596060 |
Inflammation | 27.65 | 10.75 | 26 | 80527 | 48755 | 46556754 |
Eosinophil count increased | 27.49 | 10.75 | 49 | 80504 | 7817 | 46597692 |
Inappropriate antidiuretic hormone secretion | 27.26 | 10.75 | 69 | 80484 | 14033 | 46591476 |
Throat irritation | 27.24 | 10.75 | 8 | 80545 | 28893 | 46576616 |
Mental status changes | 27.22 | 10.75 | 134 | 80419 | 37954 | 46567555 |
Coma scale | 27.02 | 10.75 | 8 | 80545 | 51 | 46605458 |
Epilepsy | 26.75 | 10.75 | 96 | 80457 | 23642 | 46581867 |
Intentional product use issue | 26.68 | 10.75 | 31 | 80522 | 52749 | 46552760 |
Influenza like illness | 25.82 | 10.75 | 37 | 80516 | 57533 | 46547976 |
Feeling hot | 25.54 | 10.75 | 17 | 80536 | 37911 | 46567598 |
Suicidal behaviour | 25.48 | 10.75 | 26 | 80527 | 2422 | 46603087 |
Myoclonus | 25.47 | 10.75 | 68 | 80485 | 14284 | 46591225 |
Impulsive behaviour | 25.37 | 10.75 | 21 | 80532 | 1494 | 46604015 |
Thought blocking | 25.30 | 10.75 | 9 | 80544 | 109 | 46605400 |
Death | 25.29 | 10.75 | 417 | 80136 | 335131 | 46270378 |
Disinhibition | 25.05 | 10.75 | 17 | 80536 | 894 | 46604615 |
Plasma cell myeloma | 24.86 | 10.75 | 24 | 80529 | 44454 | 46561055 |
Cataract | 24.82 | 10.75 | 25 | 80528 | 45390 | 46560119 |
Acquired haemophilia | 24.72 | 10.75 | 17 | 80536 | 914 | 46604595 |
Blunted affect | 24.31 | 10.75 | 10 | 80543 | 184 | 46605325 |
Bone disorder | 24.24 | 10.75 | 3 | 80550 | 20030 | 46585479 |
Device issue | 24.16 | 10.75 | 3 | 80550 | 19977 | 46585532 |
Water intoxication | 24.12 | 10.75 | 13 | 80540 | 448 | 46605061 |
Euphoric mood | 23.84 | 10.75 | 33 | 80520 | 4239 | 46601270 |
Major depression | 23.80 | 10.75 | 42 | 80511 | 6648 | 46598861 |
Fibromyalgia | 23.68 | 10.75 | 17 | 80536 | 36446 | 46569063 |
Diverticulitis | 23.36 | 10.75 | 14 | 80539 | 33025 | 46572484 |
Palpitations | 23.35 | 10.75 | 85 | 80468 | 95174 | 46510335 |
Knee arthroplasty | 23.33 | 10.75 | 6 | 80547 | 23659 | 46581850 |
Rhinorrhoea | 23.03 | 10.75 | 29 | 80524 | 47636 | 46557873 |
Mucosal inflammation | 23.01 | 10.75 | 20 | 80533 | 38956 | 46566553 |
Injection site haemorrhage | 22.98 | 10.75 | 4 | 80549 | 20705 | 46584804 |
Aspartate aminotransferase increased | 22.96 | 10.75 | 222 | 80331 | 78478 | 46527031 |
Electrocardiogram J wave | 22.89 | 10.75 | 5 | 80548 | 6 | 46605503 |
Ketoacidosis | 22.75 | 10.75 | 31 | 80522 | 3924 | 46601585 |
Hypertonia | 22.71 | 10.75 | 33 | 80520 | 4433 | 46601076 |
Maternal exposure during breast feeding | 22.68 | 10.75 | 26 | 80527 | 2763 | 46602746 |
Sciatica | 22.65 | 10.75 | 3 | 80550 | 19017 | 46586492 |
Patient dissatisfaction with treatment | 22.60 | 10.75 | 7 | 80546 | 53 | 46605456 |
Bronchitis | 22.55 | 10.75 | 100 | 80453 | 105879 | 46499630 |
Accidental overdose | 22.48 | 10.75 | 81 | 80472 | 19985 | 46585524 |
Meige's syndrome | 22.46 | 10.75 | 5 | 80548 | 7 | 46605502 |
Unevaluable event | 22.41 | 10.75 | 28 | 80525 | 46147 | 46559362 |
Pleural effusion | 22.39 | 10.75 | 71 | 80482 | 82881 | 46522628 |
Musculoskeletal stiffness | 22.37 | 10.75 | 90 | 80463 | 97903 | 46507606 |
Anaphylactic shock | 22.31 | 10.75 | 4 | 80549 | 20270 | 46585239 |
Pain in jaw | 22.28 | 10.75 | 20 | 80533 | 38352 | 46567157 |
Antiphospholipid antibodies | 22.26 | 10.75 | 9 | 80544 | 158 | 46605351 |
Urinary tract infection | 22.21 | 10.75 | 258 | 80295 | 220008 | 46385501 |
Differential white blood cell count abnormal | 22.17 | 10.75 | 14 | 80539 | 651 | 46604858 |
Electrocardiogram J wave abnormal | 22.06 | 10.75 | 5 | 80548 | 8 | 46605501 |
Limb discomfort | 22.03 | 10.75 | 6 | 80547 | 22770 | 46582739 |
Polydipsia psychogenic | 21.94 | 10.75 | 7 | 80546 | 59 | 46605450 |
Discomfort | 21.93 | 10.75 | 29 | 80524 | 46641 | 46558868 |
Drug ineffective | 21.92 | 10.75 | 952 | 79601 | 676886 | 45928623 |
Neuralgia | 21.91 | 10.75 | 5 | 80548 | 21378 | 46584131 |
Skin exfoliation | 21.86 | 10.75 | 15 | 80538 | 32923 | 46572586 |
Abnormal weight gain | 21.71 | 10.75 | 19 | 80534 | 1459 | 46604050 |
Breast discomfort | 21.65 | 10.75 | 11 | 80542 | 335 | 46605174 |
Insulin C-peptide increased | 21.64 | 10.75 | 7 | 80546 | 62 | 46605447 |
Constricted affect | 21.46 | 10.75 | 4 | 80549 | 0 | 46605509 |
Haemoglobin urine | 21.44 | 10.75 | 8 | 80545 | 112 | 46605397 |
Drug use disorder | 21.40 | 10.75 | 25 | 80528 | 2710 | 46602799 |
Cytomegalovirus infection | 21.28 | 10.75 | 3 | 80550 | 18141 | 46587368 |
Skin ulcer | 21.25 | 10.75 | 15 | 80538 | 32443 | 46573066 |
Retinal coloboma | 21.17 | 10.75 | 6 | 80547 | 32 | 46605477 |
Poisoning deliberate | 21.10 | 10.75 | 44 | 80509 | 7882 | 46597627 |
Gastrointestinal haemorrhage | 21.04 | 10.75 | 66 | 80487 | 77307 | 46528202 |
Pneumonia | 20.97 | 10.75 | 492 | 80061 | 375828 | 46229681 |
Pancreatitis | 20.94 | 10.75 | 138 | 80415 | 43489 | 46562020 |
Fluid retention | 20.79 | 10.75 | 35 | 80518 | 51011 | 46554498 |
Respiratory tract infection | 20.77 | 10.75 | 13 | 80540 | 29959 | 46575550 |
Monocyte count decreased | 20.77 | 10.75 | 20 | 80533 | 1737 | 46603772 |
Drug monitoring procedure incorrectly performed | 20.76 | 10.75 | 8 | 80545 | 123 | 46605386 |
Behaviour disorder | 20.72 | 10.75 | 21 | 80532 | 1940 | 46603569 |
Nephrolithiasis | 20.70 | 10.75 | 16 | 80537 | 33035 | 46572474 |
Hyperthermia malignant | 20.65 | 10.75 | 14 | 80539 | 735 | 46604774 |
Surgery | 20.63 | 10.75 | 12 | 80541 | 28773 | 46576736 |
Ileus paralytic | 20.62 | 10.75 | 31 | 80522 | 4292 | 46601217 |
Psychomotor skills impaired | 20.57 | 10.75 | 22 | 80531 | 2164 | 46603345 |
Muscular weakness | 20.56 | 10.75 | 85 | 80468 | 91759 | 46513750 |
Apallic syndrome | 20.48 | 10.75 | 13 | 80540 | 610 | 46604899 |
Compulsions | 20.44 | 10.75 | 9 | 80544 | 197 | 46605312 |
Akinesia | 20.35 | 10.75 | 20 | 80533 | 1781 | 46603728 |
Migraine | 20.28 | 10.75 | 58 | 80495 | 69968 | 46535541 |
Intentional product misuse | 20.21 | 10.75 | 145 | 80408 | 46983 | 46558526 |
Psychogenic visual disorder | 19.92 | 10.75 | 5 | 80548 | 15 | 46605494 |
Refusal of examination | 19.91 | 10.75 | 6 | 80547 | 41 | 46605468 |
Brain injury | 19.83 | 10.75 | 37 | 80516 | 6113 | 46599396 |
Staring | 19.81 | 10.75 | 18 | 80535 | 1452 | 46604057 |
Bradykinesia | 19.72 | 10.75 | 29 | 80524 | 3937 | 46601572 |
Thrombosis | 19.72 | 10.75 | 42 | 80511 | 56027 | 46549482 |
Flat affect | 19.70 | 10.75 | 17 | 80536 | 1281 | 46604228 |
Productive cough | 19.55 | 10.75 | 36 | 80517 | 50679 | 46554830 |
Iris coloboma | 19.54 | 10.75 | 6 | 80547 | 44 | 46605465 |
Newborn persistent pulmonary hypertension | 19.52 | 10.75 | 7 | 80546 | 87 | 46605422 |
Osteonecrosis | 19.52 | 10.75 | 10 | 80543 | 25734 | 46579775 |
Femur fracture | 19.50 | 10.75 | 21 | 80532 | 36976 | 46568533 |
Mouth ulceration | 19.50 | 10.75 | 11 | 80542 | 26821 | 46578688 |
Tubo-ovarian abscess | 19.46 | 10.75 | 10 | 80543 | 312 | 46605197 |
Gastrointestinal sounds abnormal | 19.44 | 10.75 | 27 | 80526 | 3479 | 46602030 |
Eosinophilia | 19.39 | 10.75 | 75 | 80478 | 19142 | 46586367 |
Toxic leukoencephalopathy | 19.34 | 10.75 | 12 | 80541 | 541 | 46604968 |
Withdrawal syndrome | 19.30 | 10.75 | 72 | 80481 | 18062 | 46587447 |
Neoplasm progression | 19.30 | 10.75 | 11 | 80542 | 26672 | 46578837 |
Insulin resistance | 19.15 | 10.75 | 13 | 80540 | 684 | 46604825 |
Hallucination, visual | 19.06 | 10.75 | 71 | 80482 | 17802 | 46587707 |
Product quality issue | 19.05 | 10.75 | 20 | 80533 | 35628 | 46569881 |
Hypercapnia | 19.05 | 10.75 | 31 | 80522 | 4595 | 46600914 |
Gastrointestinal disorder | 19.03 | 10.75 | 47 | 80506 | 59529 | 46545980 |
Hip arthroplasty | 19.03 | 10.75 | 4 | 80549 | 18108 | 46587401 |
Long QT syndrome | 19.03 | 10.75 | 25 | 80528 | 3055 | 46602454 |
Skin discolouration | 19.01 | 10.75 | 17 | 80536 | 32663 | 46572846 |
Haematochezia | 18.97 | 10.75 | 22 | 80531 | 37471 | 46568038 |
Throat tightness | 18.93 | 10.75 | 6 | 80547 | 20633 | 46584876 |
Nuchal rigidity | 18.89 | 10.75 | 12 | 80541 | 564 | 46604945 |
Hypercholesterolaemia | 18.83 | 10.75 | 53 | 80500 | 11477 | 46594032 |
Pressure of speech | 18.81 | 10.75 | 12 | 80541 | 568 | 46604941 |
Impaired self-care | 18.81 | 10.75 | 19 | 80534 | 1749 | 46603760 |
Tachypnoea | 18.77 | 10.75 | 61 | 80492 | 14290 | 46591219 |
Ventricular dyskinesia | 18.74 | 10.75 | 8 | 80545 | 162 | 46605347 |
Decreased gait velocity | 18.69 | 10.75 | 4 | 80549 | 4 | 46605505 |
Pulmonary mass | 18.65 | 10.75 | 4 | 80549 | 17853 | 46587656 |
Rebound psychosis | 18.61 | 10.75 | 5 | 80548 | 21 | 46605488 |
Type 1 diabetes mellitus | 18.57 | 10.75 | 24 | 80529 | 2886 | 46602623 |
Personality change due to a general medical condition | 18.43 | 10.75 | 5 | 80548 | 22 | 46605487 |
Coagulation factor VII level decreased | 18.43 | 10.75 | 5 | 80548 | 22 | 46605487 |
Bezoar | 18.39 | 10.75 | 17 | 80536 | 1402 | 46604107 |
Sinus rhythm | 18.35 | 10.75 | 12 | 80541 | 593 | 46604916 |
Rash pruritic | 18.30 | 10.75 | 30 | 80523 | 44185 | 46561324 |
Dysgeusia | 18.18 | 10.75 | 26 | 80527 | 40465 | 46565044 |
Echolalia | 18.09 | 10.75 | 8 | 80545 | 177 | 46605332 |
Suspiciousness | 18.08 | 10.75 | 10 | 80543 | 363 | 46605146 |
Parkinsonian gait | 17.84 | 10.75 | 11 | 80542 | 490 | 46605019 |
Blister | 17.81 | 10.75 | 31 | 80522 | 44600 | 46560909 |
Taciturnity | 17.80 | 10.75 | 4 | 80549 | 6 | 46605503 |
Hypomagnesaemia | 17.80 | 10.75 | 8 | 80545 | 22202 | 46583307 |
Bursitis | 17.79 | 10.75 | 6 | 80547 | 19836 | 46585673 |
Phagophobia | 17.74 | 10.75 | 5 | 80548 | 26 | 46605483 |
Caesarean section | 17.74 | 10.75 | 66 | 80487 | 16537 | 46588972 |
Grandiosity | 17.73 | 10.75 | 8 | 80545 | 186 | 46605323 |
Cellulitis | 17.70 | 10.75 | 62 | 80491 | 70226 | 46535283 |
Fungal infection | 17.61 | 10.75 | 15 | 80538 | 29505 | 46576004 |
Delusional disorder, unspecified type | 17.26 | 10.75 | 10 | 80543 | 397 | 46605112 |
Hyperglycaemic hyperosmolar nonketotic syndrome | 17.26 | 10.75 | 11 | 80542 | 520 | 46604989 |
Ataxia | 17.14 | 10.75 | 58 | 80495 | 13872 | 46591637 |
Joint stiffness | 17.14 | 10.75 | 13 | 80540 | 27095 | 46578414 |
Ketosis-prone diabetes mellitus | 17.08 | 10.75 | 4 | 80549 | 8 | 46605501 |
Kidney infection | 17.05 | 10.75 | 4 | 80549 | 16785 | 46588724 |
Condition aggravated | 17.03 | 10.75 | 548 | 80005 | 244504 | 46361005 |
Stress | 17.00 | 10.75 | 40 | 80513 | 51511 | 46553998 |
Palmar-plantar erythrodysaesthesia syndrome | 16.97 | 10.75 | 7 | 80546 | 20444 | 46585065 |
Wrong drug | 16.91 | 10.75 | 7 | 80546 | 131 | 46605378 |
Glutamate dehydrogenase increased | 16.87 | 10.75 | 5 | 80548 | 32 | 46605477 |
Loss of personal independence in daily activities | 16.83 | 10.75 | 47 | 80506 | 57136 | 46548373 |
Sinus disorder | 16.72 | 10.75 | 4 | 80549 | 16559 | 46588950 |
Contusion | 16.59 | 10.75 | 86 | 80467 | 87401 | 46518108 |
Wrong technique in product usage process | 16.56 | 10.75 | 44 | 80509 | 54378 | 46551131 |
Hepatitis toxic | 16.48 | 10.75 | 23 | 80530 | 2977 | 46602532 |
Echopraxia | 16.46 | 10.75 | 4 | 80549 | 10 | 46605499 |
Grunting | 16.46 | 10.75 | 8 | 80545 | 221 | 46605288 |
Extensor plantar response | 16.39 | 10.75 | 15 | 80538 | 1221 | 46604288 |
Morose | 16.36 | 10.75 | 5 | 80548 | 36 | 46605473 |
Genitourinary symptom | 16.35 | 10.75 | 6 | 80547 | 80 | 46605429 |
Areflexia | 16.35 | 10.75 | 23 | 80530 | 3000 | 46602509 |
Full blood count decreased | 16.29 | 10.75 | 9 | 80544 | 22202 | 46583307 |
Hallucination, olfactory | 16.23 | 10.75 | 8 | 80545 | 228 | 46605281 |
Neurosyphilis | 16.09 | 10.75 | 3 | 80550 | 0 | 46605509 |
Inborn error of metabolism | 16.09 | 10.75 | 3 | 80550 | 0 | 46605509 |
Excessive masturbation | 16.09 | 10.75 | 3 | 80550 | 0 | 46605509 |
Intermittent explosive disorder | 16.09 | 10.75 | 3 | 80550 | 0 | 46605509 |
Neonatal respiratory depression | 16.08 | 10.75 | 6 | 80547 | 84 | 46605425 |
Large for dates baby | 16.07 | 10.75 | 10 | 80543 | 453 | 46605056 |
Flight of ideas | 15.97 | 10.75 | 9 | 80544 | 339 | 46605170 |
Microphthalmos | 15.95 | 10.75 | 7 | 80546 | 152 | 46605357 |
Delusional disorder, persecutory type | 15.95 | 10.75 | 7 | 80546 | 152 | 46605357 |
Ear infection | 15.92 | 10.75 | 10 | 80543 | 23003 | 46582506 |
Electrocardiogram QT interval abnormal | 15.91 | 10.75 | 7 | 80546 | 153 | 46605356 |
Abulia | 15.85 | 10.75 | 9 | 80544 | 344 | 46605165 |
Atonic urinary bladder | 15.83 | 10.75 | 6 | 80547 | 88 | 46605421 |
Overweight | 15.83 | 10.75 | 23 | 80530 | 3090 | 46602419 |
Incontinence | 15.78 | 10.75 | 45 | 80508 | 9817 | 46595692 |
Foot fracture | 15.77 | 10.75 | 7 | 80546 | 19575 | 46585934 |
Toxic encephalopathy | 15.76 | 10.75 | 30 | 80523 | 5032 | 46600477 |
Self-medication | 15.73 | 10.75 | 19 | 80534 | 2133 | 46603376 |
Insomnia | 15.71 | 10.75 | 384 | 80169 | 164540 | 46440969 |
Lower respiratory tract infection | 15.68 | 10.75 | 46 | 80507 | 55043 | 46550466 |
Localised infection | 15.58 | 10.75 | 11 | 80542 | 23790 | 46581719 |
Terminal insomnia | 15.50 | 10.75 | 10 | 80543 | 483 | 46605026 |
Cardiac failure | 15.50 | 10.75 | 78 | 80475 | 79870 | 46525639 |
Angina pectoris | 15.49 | 10.75 | 14 | 80539 | 26761 | 46578748 |
Gastrointestinal lymphoma | 15.48 | 10.75 | 5 | 80548 | 44 | 46605465 |
Autonomic nervous system imbalance | 15.47 | 10.75 | 20 | 80533 | 2406 | 46603103 |
Gastric disorder | 15.41 | 10.75 | 14 | 80539 | 26691 | 46578818 |
Cystitis | 15.39 | 10.75 | 31 | 80522 | 42210 | 46563299 |
Rash macular | 15.33 | 10.75 | 7 | 80546 | 19253 | 46586256 |
Neuroglycopenia | 15.19 | 10.75 | 5 | 80548 | 47 | 46605462 |
Compulsive sexual behaviour | 15.19 | 10.75 | 5 | 80548 | 47 | 46605462 |
Upper gastrointestinal haemorrhage | 15.12 | 10.75 | 5 | 80548 | 16733 | 46588776 |
Drug level above therapeutic | 15.11 | 10.75 | 24 | 80529 | 3485 | 46602024 |
CSF glucose increased | 15.01 | 10.75 | 5 | 80548 | 49 | 46605460 |
Transient aphasia | 15.01 | 10.75 | 5 | 80548 | 49 | 46605460 |
Immune-mediated encephalitis | 14.74 | 10.75 | 5 | 80548 | 52 | 46605457 |
Cerebral atrophy | 14.74 | 10.75 | 28 | 80525 | 4688 | 46600821 |
Amaurosis | 14.73 | 10.75 | 10 | 80543 | 526 | 46604983 |
International normalised ratio abnormal | 14.68 | 10.75 | 22 | 80531 | 3037 | 46602472 |
Haemorrhoids | 14.68 | 10.75 | 7 | 80546 | 18770 | 46586739 |
Reduced facial expression | 14.63 | 10.75 | 14 | 80539 | 1206 | 46604303 |
Joint range of motion decreased | 14.60 | 10.75 | 4 | 80549 | 15120 | 46590389 |
Oral candidiasis | 14.55 | 10.75 | 6 | 80547 | 17526 | 46587983 |
Affective ambivalence | 14.49 | 10.75 | 4 | 80549 | 19 | 46605490 |
Pulmonary arterial hypertension | 14.48 | 10.75 | 14 | 80539 | 25914 | 46579595 |
Metastases to bone | 14.47 | 10.75 | 6 | 80547 | 17470 | 46588039 |
Hepatotoxicity | 14.45 | 10.75 | 83 | 80470 | 24926 | 46580583 |
Feelings of worthlessness | 14.42 | 10.75 | 8 | 80545 | 292 | 46605217 |
Bundle branch block right | 14.31 | 10.75 | 28 | 80525 | 4791 | 46600718 |
Glassy eyes | 14.25 | 10.75 | 5 | 80548 | 58 | 46605451 |
Haematocrit increased | 14.23 | 10.75 | 16 | 80537 | 1664 | 46603845 |
Affect lability | 14.23 | 10.75 | 38 | 80515 | 7982 | 46597527 |
Pituitary tumour benign | 14.23 | 10.75 | 16 | 80537 | 1665 | 46603844 |
Stereotypy | 14.22 | 10.75 | 9 | 80544 | 420 | 46605089 |
Blood pressure increased | 14.09 | 10.75 | 145 | 80408 | 126521 | 46478988 |
Red blood cells urine | 14.09 | 10.75 | 9 | 80544 | 427 | 46605082 |
Chronic kidney disease | 14.05 | 10.75 | 31 | 80522 | 40840 | 46564669 |
Onychogryphosis | 14.02 | 10.75 | 3 | 80550 | 3 | 46605506 |
Pelvic sepsis | 14.02 | 10.75 | 3 | 80550 | 3 | 46605506 |
Facial wasting | 14.02 | 10.75 | 3 | 80550 | 3 | 46605506 |
Analgesic drug level increased | 14.00 | 10.75 | 15 | 80538 | 1479 | 46604030 |
Skin striae | 13.98 | 10.75 | 13 | 80540 | 1080 | 46604429 |
Blood bilirubin increased | 13.98 | 10.75 | 104 | 80449 | 34080 | 46571429 |
Suspected suicide attempt | 13.94 | 10.75 | 6 | 80547 | 124 | 46605385 |
Communication disorder | 13.89 | 10.75 | 19 | 80534 | 2414 | 46603095 |
Glucocorticoids increased | 13.86 | 10.75 | 6 | 80547 | 126 | 46605383 |
Diabetic hyperosmolar coma | 13.83 | 10.75 | 9 | 80544 | 441 | 46605068 |
Night sweats | 13.78 | 10.75 | 16 | 80537 | 27234 | 46578275 |
Hypersomnia | 13.77 | 10.75 | 58 | 80495 | 15381 | 46590128 |
Acute myeloid leukaemia | 13.75 | 10.75 | 5 | 80548 | 15773 | 46589736 |
Helplessness | 13.75 | 10.75 | 7 | 80546 | 214 | 46605295 |
Encephalitis autoimmune | 13.67 | 10.75 | 13 | 80540 | 1111 | 46604398 |
Skin disorder | 13.66 | 10.75 | 11 | 80542 | 22252 | 46583257 |
Myelodysplastic syndrome | 13.66 | 10.75 | 5 | 80548 | 15706 | 46589803 |
Hypoventilation | 13.59 | 10.75 | 25 | 80528 | 4085 | 46601424 |
Gastrooesophageal reflux disease | 13.59 | 10.75 | 74 | 80479 | 74270 | 46531239 |
Opisthotonus | 13.56 | 10.75 | 8 | 80545 | 329 | 46605180 |
Asphyxia | 13.52 | 10.75 | 29 | 80524 | 5297 | 46600212 |
Chorea | 13.52 | 10.75 | 13 | 80540 | 1127 | 46604382 |
Hospitalisation | 13.50 | 10.75 | 168 | 80385 | 63217 | 46542292 |
High density lipoprotein decreased | 13.38 | 10.75 | 16 | 80537 | 1778 | 46603731 |
Hostility | 13.34 | 10.75 | 14 | 80539 | 1348 | 46604161 |
Hyperkalaemia | 13.26 | 10.75 | 44 | 80509 | 50665 | 46554844 |
Foot deformity | 13.26 | 10.75 | 5 | 80548 | 15420 | 46590089 |
Electrocardiogram abnormal | 13.23 | 10.75 | 34 | 80519 | 6978 | 46598531 |
Gastric ulcer | 13.17 | 10.75 | 11 | 80542 | 21852 | 46583657 |
Lactic acidosis | 13.13 | 10.75 | 24 | 80529 | 33885 | 46571624 |
Leukocytosis | 13.10 | 10.75 | 77 | 80476 | 23321 | 46582188 |
Brief psychotic disorder, with postpartum onset | 12.95 | 10.75 | 4 | 80549 | 30 | 46605479 |
Metastases to liver | 12.89 | 10.75 | 9 | 80544 | 19576 | 46585933 |
Lethargy | 12.85 | 10.75 | 140 | 80413 | 51031 | 46554478 |
Blood glucose | 12.83 | 10.75 | 4 | 80549 | 31 | 46605478 |
High-pitched crying | 12.81 | 10.75 | 3 | 80550 | 6 | 46605503 |
Hyperinsulinism | 12.81 | 10.75 | 3 | 80550 | 6 | 46605503 |
Dyskinesia neonatal | 12.81 | 10.75 | 3 | 80550 | 6 | 46605503 |
Lip swelling | 12.74 | 10.75 | 15 | 80538 | 25380 | 46580129 |
Brief psychotic disorder with marked stressors | 12.74 | 10.75 | 5 | 80548 | 81 | 46605428 |
Hyperinsulinaemia | 12.74 | 10.75 | 5 | 80548 | 81 | 46605428 |
Respiratory dyskinesia | 12.72 | 10.75 | 4 | 80549 | 32 | 46605477 |
Cyclothymic disorder | 12.72 | 10.75 | 4 | 80549 | 32 | 46605477 |
Fluid overload | 12.66 | 10.75 | 17 | 80536 | 27168 | 46578341 |
Tic | 12.63 | 10.75 | 13 | 80540 | 1223 | 46604286 |
Inappropriate affect | 12.63 | 10.75 | 11 | 80542 | 839 | 46604670 |
Platelet count increased | 12.59 | 10.75 | 55 | 80498 | 14819 | 46590690 |
Body mass index increased | 12.56 | 10.75 | 12 | 80541 | 1032 | 46604477 |
Anterograde amnesia | 12.55 | 10.75 | 8 | 80545 | 378 | 46605131 |
Deafness | 12.54 | 10.75 | 6 | 80547 | 16062 | 46589447 |
Hypertransaminasaemia | 12.54 | 10.75 | 22 | 80531 | 3466 | 46602043 |
Dysphonia | 12.51 | 10.75 | 30 | 80523 | 38384 | 46567125 |
Pseudobulbar palsy | 12.49 | 10.75 | 3 | 80550 | 7 | 46605502 |
Systemic infection | 12.46 | 10.75 | 10 | 80543 | 681 | 46604828 |
Drug withdrawal syndrome neonatal | 12.46 | 10.75 | 16 | 80537 | 1912 | 46603597 |
Alcohol abuse | 12.45 | 10.75 | 17 | 80536 | 2155 | 46603354 |
Sluggishness | 12.44 | 10.75 | 26 | 80527 | 4665 | 46600844 |
Bone marrow failure | 12.40 | 10.75 | 20 | 80533 | 29649 | 46575860 |
Hyperlipidaemia | 12.38 | 10.75 | 64 | 80489 | 18475 | 46587034 |
Ascites | 12.37 | 10.75 | 28 | 80525 | 36556 | 46568953 |
Poverty of speech | 12.34 | 10.75 | 7 | 80546 | 267 | 46605242 |
Dysbiosis | 12.31 | 10.75 | 9 | 80544 | 533 | 46604976 |
Breast cancer | 12.25 | 10.75 | 39 | 80514 | 45479 | 46560030 |
Breast enlargement | 12.25 | 10.75 | 14 | 80539 | 1483 | 46604026 |
Device related infection | 12.17 | 10.75 | 11 | 80542 | 21030 | 46584479 |
Wrong patient received product | 12.15 | 10.75 | 15 | 80538 | 1722 | 46603787 |
Selective eating disorder | 12.10 | 10.75 | 15 | 80538 | 1730 | 46603779 |
Lipids abnormal | 12.08 | 10.75 | 7 | 80546 | 278 | 46605231 |
Oral pain | 12.07 | 10.75 | 15 | 80538 | 24782 | 46580727 |
Thirst | 12.03 | 10.75 | 44 | 80509 | 10932 | 46594577 |
Seasonal allergy | 12.01 | 10.75 | 4 | 80549 | 13330 | 46592179 |
Speech disorder developmental | 11.99 | 10.75 | 8 | 80545 | 409 | 46605100 |
Incoherent | 11.95 | 10.75 | 25 | 80528 | 4487 | 46601022 |
Alveolar capillary dysplasia | 11.95 | 10.75 | 3 | 80550 | 9 | 46605500 |
Cleft palate | 11.91 | 10.75 | 11 | 80542 | 906 | 46604603 |
Joint effusion | 11.90 | 10.75 | 3 | 80550 | 11992 | 46593517 |
Hypophagia | 11.89 | 10.75 | 89 | 80464 | 29217 | 46576292 |
Blood urea decreased | 11.89 | 10.75 | 17 | 80536 | 2250 | 46603259 |
Eye irritation | 11.80 | 10.75 | 7 | 80546 | 16607 | 46588902 |
Antipsychotic drug level below therapeutic | 11.79 | 10.75 | 7 | 80546 | 291 | 46605218 |
Moaning | 11.79 | 10.75 | 10 | 80543 | 736 | 46604773 |
Somnolence neonatal | 11.77 | 10.75 | 5 | 80548 | 100 | 46605409 |
Homicidal ideation | 11.72 | 10.75 | 15 | 80538 | 1787 | 46603722 |
Malignant melanoma stage III | 11.71 | 10.75 | 3 | 80550 | 10 | 46605499 |
Muscle tone disorder | 11.68 | 10.75 | 5 | 80548 | 102 | 46605407 |
Female sexual dysfunction | 11.68 | 10.75 | 4 | 80549 | 43 | 46605466 |
Tendonitis | 11.66 | 10.75 | 5 | 80548 | 14272 | 46591237 |
Vomiting | 11.63 | 10.75 | 651 | 79902 | 452143 | 46153366 |
Hyponatraemic syndrome | 11.61 | 10.75 | 9 | 80544 | 583 | 46604926 |
Product storage error | 11.61 | 10.75 | 3 | 80550 | 11789 | 46593720 |
Staphylococcal infection | 11.60 | 10.75 | 28 | 80525 | 35743 | 46569766 |
Pupillary reflex impaired | 11.58 | 10.75 | 16 | 80537 | 2052 | 46603457 |
Tongue biting | 11.57 | 10.75 | 13 | 80540 | 1351 | 46604158 |
Personality disorder | 11.57 | 10.75 | 20 | 80533 | 3113 | 46602396 |
Dependent personality disorder | 11.51 | 10.75 | 4 | 80549 | 45 | 46605464 |
Crying | 11.47 | 10.75 | 69 | 80484 | 21072 | 46584437 |
Neonatal seizure | 11.43 | 10.75 | 7 | 80546 | 308 | 46605201 |
Suspected suicide | 11.40 | 10.75 | 25 | 80528 | 4636 | 46600873 |
Amimia | 11.36 | 10.75 | 4 | 80549 | 47 | 46605462 |
Distractibility | 11.35 | 10.75 | 7 | 80546 | 312 | 46605197 |
Therapy partial responder | 11.32 | 10.75 | 25 | 80528 | 4657 | 46600852 |
Total cholesterol/HDL ratio decreased | 11.28 | 10.75 | 3 | 80550 | 12 | 46605497 |
Diabetic neuropathy | 11.24 | 10.75 | 22 | 80531 | 3767 | 46601742 |
Sepsis | 11.24 | 10.75 | 166 | 80387 | 135848 | 46469661 |
Dissociation | 11.23 | 10.75 | 15 | 80538 | 1862 | 46603647 |
Orthostatic hypotension | 11.23 | 10.75 | 77 | 80476 | 24581 | 46580928 |
Sputum discoloured | 11.22 | 10.75 | 4 | 80549 | 12774 | 46592735 |
Sneezing | 11.17 | 10.75 | 4 | 80549 | 12737 | 46592772 |
Prolactin-producing pituitary tumour | 11.17 | 10.75 | 5 | 80548 | 114 | 46605395 |
Dry skin | 11.14 | 10.75 | 35 | 80518 | 40981 | 46564528 |
Right ventricular failure | 11.12 | 10.75 | 7 | 80546 | 16086 | 46589423 |
Limb injury | 11.12 | 10.75 | 10 | 80543 | 19164 | 46586345 |
Malignant neoplasm progression | 11.12 | 10.75 | 66 | 80487 | 64860 | 46540649 |
Drug abuser | 11.12 | 10.75 | 20 | 80533 | 3213 | 46602296 |
Premature delivery | 11.11 | 10.75 | 13 | 80540 | 22056 | 46583453 |
Eosinophil count abnormal | 11.11 | 10.75 | 8 | 80545 | 463 | 46605046 |
Microalbuminuria | 11.10 | 10.75 | 7 | 80546 | 325 | 46605184 |
Depressive delusion | 11.09 | 10.75 | 3 | 80550 | 13 | 46605496 |
Product use in unapproved indication | 11.07 | 10.75 | 218 | 80335 | 90055 | 46515454 |
Lipids increased | 11.03 | 10.75 | 11 | 80542 | 997 | 46604512 |
Bifascicular block | 10.97 | 10.75 | 5 | 80548 | 119 | 46605390 |
Heart rate decreased | 10.95 | 10.75 | 24 | 80529 | 31699 | 46573810 |
Clonic convulsion | 10.95 | 10.75 | 9 | 80544 | 634 | 46604875 |
Alcohol use | 10.93 | 10.75 | 17 | 80536 | 2425 | 46603084 |
Visuospatial deficit | 10.91 | 10.75 | 3 | 80550 | 14 | 46605495 |
Osteopenia | 10.89 | 10.75 | 8 | 80545 | 16953 | 46588556 |
Acute kidney injury | 10.82 | 10.75 | 317 | 80236 | 235538 | 46369971 |
Hypotonia | 10.78 | 10.75 | 35 | 80518 | 8194 | 46597315 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Neuroleptic malignant syndrome | 1578.09 | 11.48 | 820 | 85227 | 15475 | 29850956 |
Sedation | 981.54 | 11.48 | 602 | 85445 | 15771 | 29850660 |
Post-injection delirium sedation syndrome | 878.35 | 11.48 | 208 | 85839 | 185 | 29866246 |
Schizophrenia | 874.49 | 11.48 | 455 | 85592 | 8593 | 29857838 |
Psychotic disorder | 868.53 | 11.48 | 618 | 85429 | 20897 | 29845534 |
Weight increased | 623.00 | 11.48 | 912 | 85135 | 74001 | 29792430 |
Agitation | 593.00 | 11.48 | 753 | 85294 | 53320 | 29813111 |
Overdose | 576.83 | 11.48 | 938 | 85109 | 83399 | 29783032 |
Intentional self-injury | 467.42 | 11.48 | 354 | 85693 | 13178 | 29853253 |
Aggression | 456.01 | 11.48 | 546 | 85501 | 36361 | 29830070 |
Extrapyramidal disorder | 449.42 | 11.48 | 315 | 85732 | 10378 | 29856053 |
Akathisia | 415.84 | 11.48 | 241 | 85806 | 5663 | 29860768 |
Delusion | 410.46 | 11.48 | 312 | 85735 | 11677 | 29854754 |
Suicide attempt | 406.70 | 11.48 | 514 | 85533 | 36183 | 29830248 |
Hallucination, auditory | 398.92 | 11.48 | 283 | 85764 | 9506 | 29856925 |
Mania | 369.23 | 11.48 | 263 | 85784 | 8891 | 29857540 |
Sopor | 358.65 | 11.48 | 278 | 85769 | 10713 | 29855718 |
Catatonia | 319.67 | 11.48 | 183 | 85864 | 4197 | 29862234 |
Blood creatine phosphokinase increased | 316.08 | 11.48 | 500 | 85547 | 43348 | 29823083 |
Prescribed overdose | 304.56 | 11.48 | 228 | 85819 | 8333 | 29858098 |
Somnolence | 303.18 | 11.48 | 779 | 85268 | 95984 | 29770447 |
Intentional overdose | 297.58 | 11.48 | 472 | 85575 | 41009 | 29825422 |
Diabetes mellitus | 294.33 | 11.48 | 472 | 85575 | 41393 | 29825038 |
Dystonia | 289.35 | 11.48 | 233 | 85814 | 9494 | 29856937 |
Diarrhoea | 285.22 | 11.48 | 325 | 85722 | 333778 | 29532653 |
Parkinsonism | 282.04 | 11.48 | 204 | 85843 | 7065 | 29859366 |
Muscle rigidity | 272.23 | 11.48 | 230 | 85817 | 10031 | 29856400 |
Toxicity to various agents | 249.45 | 11.48 | 1088 | 84959 | 176095 | 29690336 |
Psychotic symptom | 247.92 | 11.48 | 102 | 85945 | 1087 | 29865344 |
Tachycardia | 244.75 | 11.48 | 607 | 85440 | 73132 | 29793299 |
Electrocardiogram QT prolonged | 242.29 | 11.48 | 397 | 85650 | 35438 | 29830993 |
Tardive dyskinesia | 238.51 | 11.48 | 160 | 85887 | 4897 | 29861534 |
Dysarthria | 236.86 | 11.48 | 360 | 85687 | 30130 | 29836301 |
Arthralgia | 228.00 | 11.48 | 55 | 85992 | 135736 | 29730695 |
Salivary hypersecretion | 226.65 | 11.48 | 182 | 85865 | 7384 | 29859047 |
Completed suicide | 225.65 | 11.48 | 713 | 85334 | 98779 | 29767652 |
Myocarditis | 224.61 | 11.48 | 204 | 85843 | 9807 | 29856624 |
Delirium | 217.31 | 11.48 | 406 | 85641 | 40225 | 29826206 |
Blood triglycerides increased | 216.51 | 11.48 | 233 | 85814 | 13784 | 29852647 |
Restlessness | 215.28 | 11.48 | 294 | 85753 | 22305 | 29844126 |
Type 2 diabetes mellitus | 207.89 | 11.48 | 225 | 85822 | 13397 | 29853034 |
Oculogyric crisis | 195.34 | 11.48 | 90 | 85957 | 1285 | 29865146 |
Hyperprolactinaemia | 194.13 | 11.48 | 86 | 85961 | 1114 | 29865317 |
Mental impairment | 188.70 | 11.48 | 179 | 85868 | 9098 | 29857333 |
Abnormal behaviour | 188.42 | 11.48 | 295 | 85752 | 25328 | 29841103 |
Priapism | 186.02 | 11.48 | 134 | 85913 | 4609 | 29861822 |
Dyspnoea | 185.70 | 11.48 | 429 | 85618 | 332866 | 29533565 |
Metabolic syndrome | 177.59 | 11.48 | 87 | 85960 | 1435 | 29864996 |
Coma | 177.43 | 11.48 | 372 | 85675 | 40077 | 29826354 |
Suicidal ideation | 172.43 | 11.48 | 344 | 85703 | 35770 | 29830661 |
Blood prolactin abnormal | 169.71 | 11.48 | 68 | 85979 | 673 | 29865758 |
Fatigue | 164.25 | 11.48 | 431 | 85616 | 320242 | 29546189 |
Rash | 163.96 | 11.48 | 186 | 85861 | 191703 | 29674728 |
Hypothermia | 158.33 | 11.48 | 165 | 85882 | 9402 | 29857029 |
Pain | 156.75 | 11.48 | 159 | 85888 | 172482 | 29693949 |
Diabetic ketoacidosis | 149.26 | 11.48 | 206 | 85841 | 15780 | 29850651 |
Depressed level of consciousness | 147.65 | 11.48 | 334 | 85713 | 37888 | 29828543 |
Nausea | 145.31 | 11.48 | 408 | 85639 | 296549 | 29569882 |
Paranoia | 144.57 | 11.48 | 162 | 85885 | 10026 | 29856405 |
Anaemia | 143.05 | 11.48 | 236 | 85811 | 207756 | 29658675 |
Anosognosia | 142.88 | 11.48 | 59 | 85988 | 635 | 29865796 |
Pruritus | 142.87 | 11.48 | 81 | 85966 | 118123 | 29748308 |
Blood prolactin increased | 141.58 | 11.48 | 73 | 85974 | 1349 | 29865082 |
Dyskinesia | 139.62 | 11.48 | 236 | 85811 | 21598 | 29844833 |
Increased appetite | 136.97 | 11.48 | 120 | 85927 | 5497 | 29860934 |
Disorientation | 136.65 | 11.48 | 288 | 85759 | 31130 | 29835301 |
Polydipsia | 132.45 | 11.48 | 98 | 85949 | 3515 | 29862916 |
Metabolic disorder | 130.26 | 11.48 | 97 | 85950 | 3514 | 29862917 |
Treatment noncompliance | 129.57 | 11.48 | 248 | 85799 | 25005 | 29841426 |
Pneumonia | 124.99 | 11.48 | 516 | 85531 | 333790 | 29532641 |
Bipolar disorder | 122.03 | 11.48 | 95 | 85952 | 3681 | 29862750 |
Serotonin syndrome | 121.92 | 11.48 | 199 | 85848 | 17692 | 29848739 |
Diabetic coma | 119.48 | 11.48 | 56 | 85991 | 833 | 29865598 |
Death | 119.42 | 11.48 | 575 | 85472 | 356708 | 29509723 |
Sexual dysfunction | 118.64 | 11.48 | 114 | 85933 | 5887 | 29860544 |
Disturbance in social behaviour | 116.90 | 11.48 | 65 | 85982 | 1406 | 29865025 |
Malignant neoplasm progression | 116.00 | 11.48 | 32 | 86015 | 72255 | 29794176 |
Schizoaffective disorder | 115.98 | 11.48 | 58 | 85989 | 1002 | 29865429 |
Thinking abnormal | 114.77 | 11.48 | 106 | 85941 | 5205 | 29861226 |
Blood cholesterol increased | 114.61 | 11.48 | 188 | 85859 | 16782 | 29849649 |
Rhabdomyolysis | 112.70 | 11.48 | 420 | 85627 | 63160 | 29803271 |
Confusional state | 112.48 | 11.48 | 717 | 85330 | 134117 | 29732314 |
Psychomotor hyperactivity | 111.97 | 11.48 | 128 | 85919 | 8096 | 29858335 |
Cardiac failure congestive | 110.63 | 11.48 | 52 | 85995 | 84355 | 29782076 |
Obesity | 109.52 | 11.48 | 129 | 85918 | 8426 | 29858005 |
Cough | 109.13 | 11.48 | 120 | 85927 | 125522 | 29740909 |
Emotional poverty | 104.25 | 11.48 | 39 | 86008 | 315 | 29866116 |
Miosis | 104.13 | 11.48 | 120 | 85927 | 7656 | 29858775 |
Granulocytopenia | 104.13 | 11.48 | 108 | 85939 | 6118 | 29860313 |
Acute kidney injury | 102.64 | 11.48 | 422 | 85625 | 273420 | 29593011 |
Disease progression | 101.95 | 11.48 | 51 | 85996 | 79823 | 29786608 |
Antipsychotic drug level below therapeutic | 101.91 | 11.48 | 58 | 85989 | 1314 | 29865117 |
Rheumatoid arthritis | 100.88 | 11.48 | 4 | 86043 | 41193 | 29825238 |
Speech disorder | 100.03 | 11.48 | 219 | 85828 | 24293 | 29842138 |
Disinhibition | 99.74 | 11.48 | 65 | 85982 | 1892 | 29864539 |
Atrial fibrillation | 98.68 | 11.48 | 99 | 85948 | 108025 | 29758406 |
Pain in extremity | 98.23 | 11.48 | 103 | 85944 | 110118 | 29756313 |
Negativism | 97.04 | 11.48 | 38 | 86009 | 352 | 29866079 |
Psychiatric decompensation | 96.10 | 11.48 | 55 | 85992 | 1260 | 29865171 |
Febrile neutropenia | 94.75 | 11.48 | 100 | 85947 | 106593 | 29759838 |
Drug interaction | 93.95 | 11.48 | 930 | 85117 | 198638 | 29667793 |
Anxiety | 93.69 | 11.48 | 507 | 85540 | 89364 | 29777067 |
Tremor | 93.14 | 11.48 | 446 | 85601 | 74917 | 29791514 |
Obsessive-compulsive disorder | 90.16 | 11.48 | 83 | 85964 | 4058 | 29862373 |
Mental disorder | 89.47 | 11.48 | 148 | 85899 | 13301 | 29853130 |
Gastrointestinal haemorrhage | 88.77 | 11.48 | 66 | 85981 | 83380 | 29783051 |
Headache | 87.08 | 11.48 | 253 | 85794 | 182053 | 29684378 |
Plasma cell myeloma | 87.01 | 11.48 | 23 | 86024 | 53439 | 29812992 |
Antipsychotic drug level above therapeutic | 87.00 | 11.48 | 48 | 85999 | 1022 | 29865409 |
Hepatic steatosis | 86.85 | 11.48 | 154 | 85893 | 14639 | 29851792 |
Interstitial lung disease | 85.39 | 11.48 | 33 | 86014 | 60164 | 29806267 |
Renal impairment | 85.23 | 11.48 | 70 | 85977 | 84114 | 29782317 |
Persecutory delusion | 85.15 | 11.48 | 61 | 85986 | 2079 | 29864352 |
Drug abuse | 84.86 | 11.48 | 462 | 85585 | 81610 | 29784821 |
Pneumonia aspiration | 84.75 | 11.48 | 270 | 85777 | 37510 | 29828921 |
Urticaria | 82.46 | 11.48 | 27 | 86020 | 54579 | 29811852 |
Psoriasis | 82.34 | 11.48 | 12 | 86035 | 42494 | 29823937 |
Irritability | 80.85 | 11.48 | 194 | 85853 | 22856 | 29843575 |
Joint swelling | 80.70 | 11.48 | 18 | 86029 | 46928 | 29819503 |
Decreased appetite | 79.12 | 11.48 | 198 | 85849 | 149712 | 29716719 |
Euphoric mood | 78.27 | 11.48 | 78 | 85969 | 4212 | 29862219 |
Dyslipidaemia | 77.73 | 11.48 | 89 | 85958 | 5638 | 29860793 |
Oedema peripheral | 76.47 | 11.48 | 116 | 85931 | 105716 | 29760715 |
Type 1 diabetes mellitus | 74.50 | 11.48 | 71 | 85976 | 3628 | 29862803 |
Leukopenia | 74.24 | 11.48 | 339 | 85708 | 55820 | 29810611 |
Hypomania | 73.42 | 11.48 | 57 | 85990 | 2199 | 29864232 |
Back pain | 72.64 | 11.48 | 114 | 85933 | 102482 | 29763949 |
Infusion related reaction | 70.84 | 11.48 | 15 | 86032 | 40549 | 29825882 |
Blepharospasm | 68.39 | 11.48 | 39 | 86008 | 887 | 29865544 |
Mucosal inflammation | 68.33 | 11.48 | 5 | 86042 | 30489 | 29835942 |
Neuropathy peripheral | 67.20 | 11.48 | 62 | 85985 | 70413 | 29796018 |
Abdominal pain | 67.12 | 11.48 | 185 | 85862 | 135469 | 29730962 |
Bradyphrenia | 66.82 | 11.48 | 69 | 85978 | 3888 | 29862543 |
White blood cell count increased | 65.25 | 11.48 | 256 | 85791 | 39417 | 29827014 |
Renal failure | 65.21 | 11.48 | 174 | 85873 | 128792 | 29737639 |
Delusional disorder, persecutory type | 64.47 | 11.48 | 26 | 86021 | 262 | 29866169 |
Peripheral swelling | 64.04 | 11.48 | 49 | 85998 | 61025 | 29805406 |
Social avoidant behaviour | 63.53 | 11.48 | 58 | 85989 | 2805 | 29863626 |
Drug hypersensitivity | 62.17 | 11.48 | 63 | 85984 | 68456 | 29797975 |
Herpes zoster | 61.50 | 11.48 | 7 | 86040 | 29936 | 29836495 |
Erythema | 60.79 | 11.48 | 80 | 85967 | 77371 | 29789060 |
Respiratory depression | 60.25 | 11.48 | 114 | 85933 | 11389 | 29855042 |
Dyspnoea exertional | 60.06 | 11.48 | 14 | 86033 | 35416 | 29831015 |
Psychiatric symptom | 59.01 | 11.48 | 60 | 85987 | 3319 | 29863112 |
Stomatitis | 58.85 | 11.48 | 17 | 86030 | 37262 | 29829169 |
Antipsychotic drug level increased | 58.57 | 11.48 | 58 | 85989 | 3108 | 29863323 |
Septic shock | 58.26 | 11.48 | 58 | 85989 | 63549 | 29802882 |
Drooling | 57.35 | 11.48 | 56 | 85991 | 2949 | 29863482 |
Obsessive thoughts | 57.04 | 11.48 | 31 | 86016 | 640 | 29865791 |
International normalised ratio increased | 55.79 | 11.48 | 34 | 86013 | 47705 | 29818726 |
Bradykinesia | 55.76 | 11.48 | 57 | 85990 | 3173 | 29863258 |
Tension | 55.46 | 11.48 | 42 | 86005 | 1561 | 29864870 |
Depressive symptom | 54.49 | 11.48 | 42 | 86005 | 1603 | 29864828 |
Visceral congestion | 54.37 | 11.48 | 28 | 86019 | 516 | 29865915 |
Sinus tachycardia | 53.83 | 11.48 | 130 | 85917 | 15374 | 29851057 |
Anticholinergic syndrome | 53.70 | 11.48 | 32 | 86015 | 792 | 29865639 |
Eosinophilic myocarditis | 53.50 | 11.48 | 26 | 86021 | 421 | 29866010 |
Influenza | 53.43 | 11.48 | 29 | 86018 | 43369 | 29823062 |
Apathy | 53.25 | 11.48 | 77 | 85970 | 6155 | 29860276 |
Hyperglycaemia | 52.99 | 11.48 | 221 | 85826 | 34979 | 29831452 |
Haemorrhage | 52.22 | 11.48 | 34 | 86013 | 46045 | 29820386 |
Hyperkalaemia | 51.98 | 11.48 | 68 | 85979 | 65942 | 29800489 |
Withdrawal syndrome | 51.07 | 11.48 | 105 | 85942 | 11145 | 29855286 |
Spasmodic dysphonia | 50.98 | 11.48 | 16 | 86031 | 70 | 29866361 |
Water intoxication | 50.64 | 11.48 | 26 | 86021 | 476 | 29865955 |
Cerebrovascular accident | 49.87 | 11.48 | 103 | 85944 | 83374 | 29783057 |
Hallucination | 49.87 | 11.48 | 275 | 85772 | 48784 | 29817647 |
Melaena | 49.03 | 11.48 | 16 | 86031 | 32421 | 29834010 |
Neutrophil count increased | 48.48 | 11.48 | 124 | 85923 | 15199 | 29851232 |
Agranulocytosis | 48.45 | 11.48 | 156 | 85891 | 21786 | 29844645 |
Infection | 47.78 | 11.48 | 95 | 85952 | 77979 | 29788452 |
Refusal of treatment by patient | 46.97 | 11.48 | 65 | 85982 | 4988 | 29861443 |
Self-injurious ideation | 46.68 | 11.48 | 38 | 86009 | 1571 | 29864860 |
Mutism | 46.18 | 11.48 | 28 | 86019 | 716 | 29865715 |
Hyperammonaemia | 45.42 | 11.48 | 67 | 85980 | 5453 | 29860978 |
Derealisation | 45.07 | 11.48 | 25 | 86022 | 538 | 29865893 |
Pleurothotonus | 44.98 | 11.48 | 31 | 86016 | 992 | 29865439 |
Loss of consciousness | 44.83 | 11.48 | 385 | 85662 | 78990 | 29787441 |
Sudden death | 44.56 | 11.48 | 121 | 85926 | 15371 | 29851060 |
Asthenia | 44.45 | 11.48 | 414 | 85633 | 220876 | 29645555 |
Grandiosity | 44.23 | 11.48 | 21 | 86026 | 322 | 29866109 |
Cognitive disorder | 44.03 | 11.48 | 159 | 85888 | 23531 | 29842900 |
Logorrhoea | 43.91 | 11.48 | 41 | 86006 | 2041 | 29864390 |
Unresponsive to stimuli | 43.85 | 11.48 | 171 | 85876 | 26248 | 29840183 |
Therapeutic product effect variable | 42.84 | 11.48 | 34 | 86013 | 1355 | 29865076 |
Delusion of grandeur | 42.83 | 11.48 | 21 | 86026 | 347 | 29866084 |
Chills | 42.58 | 11.48 | 90 | 85957 | 72248 | 29794183 |
Pleural effusion | 42.07 | 11.48 | 94 | 85953 | 73972 | 29792459 |
Hanging | 41.82 | 11.48 | 15 | 86032 | 106 | 29866325 |
Sepsis | 41.75 | 11.48 | 248 | 85799 | 146147 | 29720284 |
Suspiciousness | 41.72 | 11.48 | 21 | 86026 | 368 | 29866063 |
Delusion of replacement | 41.65 | 11.48 | 16 | 86031 | 140 | 29866291 |
Myocardial infarction | 41.24 | 11.48 | 203 | 85844 | 125422 | 29741009 |
Xanthoma | 40.98 | 11.48 | 14 | 86033 | 84 | 29866347 |
Hypertriglyceridaemia | 40.86 | 11.48 | 79 | 85968 | 8019 | 29858412 |
Cytomegalovirus infection | 40.83 | 11.48 | 9 | 86038 | 23665 | 29842766 |
Musculoskeletal pain | 40.60 | 11.48 | 19 | 86028 | 30921 | 29835510 |
Insomnia | 40.43 | 11.48 | 428 | 85619 | 92908 | 29773523 |
Feeling guilty | 40.39 | 11.48 | 19 | 86028 | 285 | 29866146 |
Cardiac failure | 40.30 | 11.48 | 115 | 85932 | 83303 | 29783128 |
Acute myocardial infarction | 40.19 | 11.48 | 56 | 85991 | 52883 | 29813548 |
Nasopharyngitis | 40.11 | 11.48 | 67 | 85980 | 58782 | 29807649 |
Hyperreflexia | 40.02 | 11.48 | 45 | 86002 | 2794 | 29863637 |
Blood glucose increased | 39.89 | 11.48 | 308 | 85739 | 61222 | 29805209 |
Weight decreased | 39.77 | 11.48 | 262 | 85785 | 150659 | 29715772 |
Abdominal discomfort | 39.72 | 11.48 | 49 | 85998 | 48742 | 29817689 |
Product dose omission issue | 39.54 | 11.48 | 133 | 85914 | 91498 | 29774933 |
Thrombosis | 39.25 | 11.48 | 38 | 86009 | 42193 | 29824238 |
General physical health deterioration | 39.19 | 11.48 | 151 | 85896 | 99793 | 29766638 |
Blood creatinine increased | 39.17 | 11.48 | 133 | 85914 | 91242 | 29775189 |
Inappropriate affect | 38.97 | 11.48 | 23 | 86024 | 559 | 29865872 |
Hallucination, visual | 38.74 | 11.48 | 118 | 85929 | 15995 | 29850436 |
Breast engorgement | 38.54 | 11.48 | 9 | 86038 | 7 | 29866424 |
Coronary artery disease | 38.33 | 11.48 | 52 | 85995 | 49660 | 29816771 |
Prostate cancer | 37.67 | 11.48 | 11 | 86036 | 23946 | 29842485 |
Arthropathy | 37.58 | 11.48 | 7 | 86040 | 20720 | 29845711 |
Pneumonitis | 37.37 | 11.48 | 16 | 86031 | 27438 | 29838993 |
Eosinophil count decreased | 37.15 | 11.48 | 29 | 86018 | 1128 | 29865303 |
Diabetic hyperosmolar coma | 37.09 | 11.48 | 19 | 86028 | 346 | 29866085 |
Stupor | 36.92 | 11.48 | 44 | 86003 | 2909 | 29863522 |
Eye movement disorder | 36.82 | 11.48 | 51 | 85996 | 3917 | 29862514 |
Asthma | 36.68 | 11.48 | 30 | 86017 | 36144 | 29830287 |
Haemoglobin decreased | 36.51 | 11.48 | 186 | 85861 | 113912 | 29752519 |
Chronic kidney disease | 36.40 | 11.48 | 33 | 86014 | 37805 | 29828626 |
Ascites | 36.16 | 11.48 | 30 | 86017 | 35891 | 29830540 |
Aspiration | 36.12 | 11.48 | 88 | 85959 | 10463 | 29855968 |
Sedation complication | 36.03 | 11.48 | 25 | 86022 | 809 | 29865622 |
Diverticulitis | 36.02 | 11.48 | 4 | 86043 | 17441 | 29848990 |
Angina pectoris | 35.93 | 11.48 | 20 | 86027 | 29498 | 29836933 |
Psychomotor retardation | 35.76 | 11.48 | 39 | 86008 | 2340 | 29864091 |
Gout | 35.67 | 11.48 | 4 | 86043 | 17311 | 29849120 |
Faecaloma | 35.57 | 11.48 | 53 | 85994 | 4352 | 29862079 |
Anaphylactic reaction | 35.47 | 11.48 | 18 | 86029 | 27964 | 29838467 |
Arthritis | 35.21 | 11.48 | 13 | 86034 | 24388 | 29842043 |
Disturbance in attention | 34.93 | 11.48 | 141 | 85906 | 21988 | 29844443 |
Torticollis | 34.63 | 11.48 | 27 | 86020 | 1048 | 29865383 |
Drug withdrawal syndrome neonatal | 34.37 | 11.48 | 44 | 86003 | 3131 | 29863300 |
Bipolar I disorder | 34.36 | 11.48 | 24 | 86023 | 785 | 29865646 |
Multiple organ dysfunction syndrome | 34.10 | 11.48 | 83 | 85964 | 63404 | 29803027 |
Cold-stimulus headache | 33.99 | 11.48 | 7 | 86040 | 0 | 29866431 |
Psychotic behaviour | 33.89 | 11.48 | 20 | 86027 | 486 | 29865945 |
Megacolon | 33.74 | 11.48 | 32 | 86015 | 1625 | 29864806 |
Cardiomyopathy | 33.73 | 11.48 | 108 | 85939 | 15035 | 29851396 |
Hypersensitivity | 33.68 | 11.48 | 65 | 85982 | 53963 | 29812468 |
Ataxia | 33.44 | 11.48 | 90 | 85957 | 11372 | 29855059 |
Sinusitis | 33.38 | 11.48 | 28 | 86019 | 33317 | 29833114 |
Angioedema | 33.06 | 11.48 | 30 | 86017 | 34354 | 29832077 |
Ketoacidosis | 33.06 | 11.48 | 47 | 86000 | 3699 | 29862732 |
Eosinophil count increased | 33.04 | 11.48 | 69 | 85978 | 7404 | 29859027 |
Generalised tonic-clonic seizure | 32.81 | 11.48 | 127 | 85920 | 19424 | 29847007 |
Food craving | 32.78 | 11.48 | 17 | 86030 | 318 | 29866113 |
Antisocial behaviour | 32.60 | 11.48 | 16 | 86031 | 265 | 29866166 |
Haematuria | 32.48 | 11.48 | 49 | 85998 | 44785 | 29821646 |
Delusional disorder, unspecified type | 32.43 | 11.48 | 23 | 86024 | 771 | 29865660 |
Pancytopenia | 32.38 | 11.48 | 130 | 85917 | 84922 | 29781509 |
Colitis ischaemic | 32.37 | 11.48 | 59 | 85988 | 5727 | 29860704 |
Posture abnormal | 32.37 | 11.48 | 33 | 86014 | 1831 | 29864600 |
Hyponatraemia | 32.36 | 11.48 | 315 | 85732 | 66887 | 29799544 |
Obsessive-compulsive symptom | 32.34 | 11.48 | 11 | 86036 | 65 | 29866366 |
Hyperbilirubinaemia | 32.30 | 11.48 | 5 | 86042 | 16937 | 29849494 |
Coma scale abnormal | 32.24 | 11.48 | 44 | 86003 | 3332 | 29863099 |
Injection site pain | 32.17 | 11.48 | 24 | 86023 | 30286 | 29836145 |
Withdrawal catatonia | 32.06 | 11.48 | 11 | 86036 | 67 | 29866364 |
Staphylococcal infection | 31.99 | 11.48 | 24 | 86023 | 30200 | 29836231 |
Oral discharge | 31.97 | 11.48 | 13 | 86034 | 134 | 29866297 |
Colitis | 31.95 | 11.48 | 25 | 86022 | 30795 | 29835636 |
Physical assault | 31.77 | 11.48 | 27 | 86020 | 1186 | 29865245 |
Rebound psychosis | 31.64 | 11.48 | 13 | 86034 | 138 | 29866293 |
Nephrolithiasis | 31.39 | 11.48 | 16 | 86031 | 24794 | 29841637 |
Intentional product use issue | 31.37 | 11.48 | 35 | 86012 | 36405 | 29830026 |
Cogwheel rigidity | 31.22 | 11.48 | 26 | 86021 | 1110 | 29865321 |
Somatic symptom disorder | 31.22 | 11.48 | 19 | 86028 | 489 | 29865942 |
Skin exfoliation | 30.76 | 11.48 | 14 | 86033 | 23158 | 29843273 |
Hunger | 30.70 | 11.48 | 28 | 86019 | 1352 | 29865079 |
Acute psychosis | 30.40 | 11.48 | 32 | 86015 | 1844 | 29864587 |
Hypercholesterolaemia | 30.02 | 11.48 | 67 | 85980 | 7525 | 29858906 |
Personality change | 29.76 | 11.48 | 50 | 85997 | 4550 | 29861881 |
Dyspepsia | 29.71 | 11.48 | 26 | 86021 | 30303 | 29836128 |
Incoherent | 29.67 | 11.48 | 47 | 86000 | 4071 | 29862360 |
Hyperphagia | 29.53 | 11.48 | 27 | 86020 | 1308 | 29865123 |
Wrong patient received product | 29.45 | 11.48 | 31 | 86016 | 1786 | 29864645 |
Hospitalisation | 29.36 | 11.48 | 223 | 85824 | 44096 | 29822335 |
Myalgia | 29.30 | 11.48 | 117 | 85930 | 76550 | 29789881 |
Blunted affect | 29.29 | 11.48 | 15 | 86032 | 273 | 29866158 |
Overweight | 29.27 | 11.48 | 28 | 86019 | 1437 | 29864994 |
Paradoxical embolism | 29.13 | 11.48 | 6 | 86041 | 0 | 29866431 |
Unevaluable event | 29.07 | 11.48 | 29 | 86018 | 31756 | 29834675 |
Cerebrovascular stenosis | 29.07 | 11.48 | 11 | 86036 | 92 | 29866339 |
Hyperlipidaemia | 29.01 | 11.48 | 97 | 85950 | 13810 | 29852621 |
Agitated depression | 28.79 | 11.48 | 14 | 86033 | 227 | 29866204 |
Mydriasis | 28.67 | 11.48 | 58 | 85989 | 6085 | 29860346 |
Wheezing | 28.56 | 11.48 | 28 | 86019 | 30910 | 29835521 |
Flat affect | 28.56 | 11.48 | 22 | 86025 | 839 | 29865592 |
Judgement impaired | 28.40 | 11.48 | 20 | 86027 | 663 | 29865768 |
Urinary incontinence | 28.39 | 11.48 | 110 | 85937 | 16830 | 29849601 |
Muscular weakness | 28.39 | 11.48 | 91 | 85956 | 63554 | 29802877 |
Pressure of speech | 28.38 | 11.48 | 17 | 86030 | 425 | 29866006 |
Altered state of consciousness | 28.37 | 11.48 | 123 | 85924 | 19796 | 29846635 |
Swelling | 28.37 | 11.48 | 37 | 86010 | 35938 | 29830493 |
Pulmonary embolism | 28.27 | 11.48 | 346 | 85701 | 77789 | 29788642 |
Candida infection | 28.25 | 11.48 | 5 | 86042 | 15357 | 29851074 |
Perseveration | 28.17 | 11.48 | 11 | 86036 | 101 | 29866330 |
Neutropenia | 28.09 | 11.48 | 522 | 85525 | 128018 | 29738413 |
Long QT syndrome | 27.92 | 11.48 | 34 | 86013 | 2299 | 29864132 |
Osteoarthritis | 27.82 | 11.48 | 9 | 86038 | 18340 | 29848091 |
Hyperhidrosis | 27.80 | 11.48 | 305 | 85742 | 66785 | 29799646 |
Fluid retention | 27.57 | 11.48 | 19 | 86028 | 24979 | 29841452 |
Product substitution issue | 27.49 | 11.48 | 77 | 85970 | 9958 | 29856473 |
Electroencephalogram abnormal | 27.45 | 11.48 | 34 | 86013 | 2340 | 29864091 |
Bronchitis | 27.16 | 11.48 | 44 | 86003 | 39081 | 29827350 |
Dysgeusia | 27.15 | 11.48 | 19 | 86028 | 24782 | 29841649 |
Myelodysplastic syndrome | 27.10 | 11.48 | 10 | 86037 | 18768 | 29847663 |
Full blood count decreased | 27.05 | 11.48 | 6 | 86041 | 15711 | 29850720 |
Staring | 26.97 | 11.48 | 27 | 86020 | 1466 | 29864965 |
Dysphagia | 26.92 | 11.48 | 265 | 85782 | 56433 | 29809998 |
Autonomic nervous system imbalance | 26.91 | 11.48 | 34 | 86013 | 2387 | 29864044 |
Alanine aminotransferase increased | 26.91 | 11.48 | 329 | 85718 | 73947 | 29792484 |
Choreoathetosis | 26.79 | 11.48 | 22 | 86025 | 921 | 29865510 |
Illness anxiety disorder | 26.77 | 11.48 | 12 | 86035 | 160 | 29866271 |
Osteonecrosis of jaw | 26.73 | 11.48 | 10 | 86037 | 18608 | 29847823 |
Tubulointerstitial nephritis | 26.73 | 11.48 | 9 | 86038 | 17882 | 29848549 |
Muscle spasms | 26.68 | 11.48 | 96 | 85951 | 64742 | 29801689 |
Camptocormia | 26.64 | 11.48 | 12 | 86035 | 162 | 29866269 |
Productive cough | 26.63 | 11.48 | 28 | 86019 | 29925 | 29836506 |
Urinary tract infection | 26.53 | 11.48 | 115 | 85932 | 73544 | 29792887 |
Enuresis | 26.52 | 11.48 | 29 | 86018 | 1745 | 29864686 |
Depression | 26.32 | 11.48 | 385 | 85662 | 90052 | 29776379 |
Troponin increased | 26.30 | 11.48 | 70 | 85977 | 8787 | 29857644 |
Hypertonia | 26.18 | 11.48 | 46 | 86001 | 4339 | 29862092 |
Dehydration | 26.11 | 11.48 | 228 | 85819 | 123311 | 29743120 |
Protrusion tongue | 26.02 | 11.48 | 13 | 86034 | 224 | 29866207 |
Erectile dysfunction | 25.95 | 11.48 | 112 | 85935 | 17990 | 29848441 |
Cerebellar syndrome | 25.87 | 11.48 | 31 | 86016 | 2061 | 29864370 |
Chronic obstructive pulmonary disease | 25.80 | 11.48 | 59 | 85988 | 46067 | 29820364 |
Leukocytosis | 25.61 | 11.48 | 126 | 85921 | 21376 | 29845055 |
Pulmonary fibrosis | 25.53 | 11.48 | 7 | 86040 | 15883 | 29850548 |
Behaviour disorder | 25.44 | 11.48 | 33 | 86014 | 2379 | 29864052 |
Haematoma | 25.37 | 11.48 | 19 | 86028 | 23934 | 29842497 |
Aspartate aminotransferase increased | 25.22 | 11.48 | 286 | 85761 | 63136 | 29803295 |
Poisoning | 25.19 | 11.48 | 81 | 85966 | 11301 | 29855130 |
Symptom masked | 25.13 | 11.48 | 16 | 86031 | 447 | 29865984 |
Epistaxis | 24.87 | 11.48 | 74 | 85973 | 52907 | 29813524 |
Oedema | 24.86 | 11.48 | 54 | 85993 | 42939 | 29823492 |
Delusional perception | 24.65 | 11.48 | 11 | 86036 | 145 | 29866286 |
Salivary gland calculus | 24.46 | 11.48 | 8 | 86039 | 41 | 29866390 |
Waxy flexibility | 24.43 | 11.48 | 10 | 86037 | 105 | 29866326 |
Osteonecrosis | 24.31 | 11.48 | 8 | 86039 | 16127 | 29850304 |
Prostatic specific antigen increased | 24.17 | 11.48 | 3 | 86044 | 12001 | 29854430 |
Dementia with Lewy bodies | 24.15 | 11.48 | 17 | 86030 | 563 | 29865868 |
Depressed mood | 24.13 | 11.48 | 105 | 85942 | 16924 | 29849507 |
Hyperglycaemic hyperosmolar nonketotic syndrome | 24.13 | 11.48 | 21 | 86026 | 953 | 29865478 |
Metastases to liver | 24.06 | 11.48 | 3 | 86044 | 11962 | 29854469 |
Respiratory arrest | 23.94 | 11.48 | 155 | 85892 | 29103 | 29837328 |
Rhinorrhoea | 23.93 | 11.48 | 15 | 86032 | 20739 | 29845692 |
Hepatic failure | 23.90 | 11.48 | 38 | 86009 | 34005 | 29832426 |
Malignant catatonia | 23.86 | 11.48 | 10 | 86037 | 112 | 29866319 |
Neoplasm progression | 23.75 | 11.48 | 11 | 86036 | 18012 | 29848419 |
Exhibitionism | 23.56 | 11.48 | 8 | 86039 | 47 | 29866384 |
Poisoning deliberate | 23.23 | 11.48 | 52 | 85995 | 5852 | 29860579 |
Body temperature increased | 23.18 | 11.48 | 94 | 85953 | 14686 | 29851745 |
Hallucinations, mixed | 23.17 | 11.48 | 32 | 86015 | 2451 | 29863980 |
Impaired self-care | 23.16 | 11.48 | 20 | 86027 | 898 | 29865533 |
Hypotonia neonatal | 23.13 | 11.48 | 21 | 86026 | 1008 | 29865423 |
Palmar-plantar erythrodysaesthesia syndrome | 23.07 | 11.48 | 7 | 86040 | 14863 | 29851568 |
Neutrophil count decreased | 22.94 | 11.48 | 204 | 85843 | 42250 | 29824181 |
Disorganised speech | 22.65 | 11.48 | 16 | 86031 | 533 | 29865898 |
Bronchopulmonary aspergillosis | 22.59 | 11.48 | 4 | 86043 | 12280 | 29854151 |
Selective eating disorder | 22.56 | 11.48 | 26 | 86021 | 1658 | 29864773 |
Compulsive sexual behaviour | 22.51 | 11.48 | 12 | 86035 | 238 | 29866193 |
Ileus paralytic | 22.50 | 11.48 | 50 | 85997 | 5598 | 29860833 |
Impulsive behaviour | 22.49 | 11.48 | 28 | 86019 | 1937 | 29864494 |
Drug monitoring procedure incorrectly performed | 22.47 | 11.48 | 11 | 86036 | 181 | 29866250 |
Patient restraint | 22.47 | 11.48 | 9 | 86038 | 89 | 29866342 |
Hallucination, olfactory | 22.42 | 11.48 | 11 | 86036 | 182 | 29866249 |
Thrombocytopenia | 22.33 | 11.48 | 269 | 85778 | 136775 | 29729656 |
High density lipoprotein decreased | 22.26 | 11.48 | 36 | 86011 | 3174 | 29863257 |
Acute myeloid leukaemia | 22.20 | 11.48 | 12 | 86035 | 17994 | 29848437 |
Heat stroke | 22.04 | 11.48 | 19 | 86028 | 851 | 29865580 |
Tumour lysis syndrome | 22.01 | 11.48 | 5 | 86042 | 12880 | 29853551 |
Myoclonus | 21.95 | 11.48 | 86 | 85961 | 13226 | 29853205 |
COVID-19 | 21.92 | 11.48 | 12 | 86035 | 17866 | 29848565 |
Pancreatitis haemorrhagic | 21.91 | 11.48 | 13 | 86034 | 319 | 29866112 |
Homicidal ideation | 21.88 | 11.48 | 31 | 86016 | 2432 | 29863999 |
Drug level above therapeutic | 21.81 | 11.48 | 34 | 86013 | 2905 | 29863526 |
Chest discomfort | 21.73 | 11.48 | 63 | 85984 | 45417 | 29821014 |
Dysphonia | 21.61 | 11.48 | 14 | 86033 | 19018 | 29847413 |
Asphyxia | 21.59 | 11.48 | 48 | 85999 | 5377 | 29861054 |
Mental status changes | 21.51 | 11.48 | 181 | 85866 | 36898 | 29829533 |
Total cholesterol/HDL ratio increased | 21.50 | 11.48 | 10 | 86037 | 146 | 29866285 |
Rash pruritic | 21.33 | 11.48 | 20 | 86027 | 22552 | 29843879 |
Gamma-glutamyltransferase increased | 21.33 | 11.48 | 151 | 85896 | 29199 | 29837232 |
Bacteraemia | 21.28 | 11.48 | 9 | 86038 | 15551 | 29850880 |
Renal disorder | 21.02 | 11.48 | 22 | 86025 | 23562 | 29842869 |
Polyuria | 20.94 | 11.48 | 57 | 85990 | 7249 | 29859182 |
Blood ketone body | 20.93 | 11.48 | 8 | 86039 | 69 | 29866362 |
White blood cell count decreased | 20.85 | 11.48 | 348 | 85699 | 83599 | 29782832 |
Transient ischaemic attack | 20.83 | 11.48 | 25 | 86022 | 25175 | 29841256 |
Drug level increased | 20.76 | 11.48 | 106 | 85941 | 18248 | 29848183 |
Inappropriate antidiuretic hormone secretion | 20.66 | 11.48 | 76 | 85971 | 11346 | 29855085 |
Alcohol use | 20.64 | 11.48 | 38 | 86009 | 3717 | 29862714 |
Haematochezia | 20.61 | 11.48 | 42 | 86005 | 34180 | 29832251 |
Abdominal pain upper | 20.54 | 11.48 | 101 | 85946 | 62450 | 29803981 |
C-reactive protein increased | 20.54 | 11.48 | 203 | 85844 | 43270 | 29823161 |
Coagulopathy | 20.45 | 11.48 | 14 | 86033 | 18473 | 29847958 |
Hepatitis C virus test positive | 20.45 | 11.48 | 14 | 86033 | 443 | 29865988 |
Stereotypy | 20.39 | 11.48 | 15 | 86032 | 533 | 29865898 |
Panic attack | 20.33 | 11.48 | 63 | 85984 | 8618 | 29857813 |
Clostridium difficile infection | 20.23 | 11.48 | 10 | 86037 | 15773 | 29850658 |
Circadian rhythm sleep disorder | 20.17 | 11.48 | 13 | 86034 | 371 | 29866060 |
Somatic hallucination | 20.17 | 11.48 | 6 | 86041 | 21 | 29866410 |
Neurodegenerative disorder | 20.07 | 11.48 | 11 | 86036 | 231 | 29866200 |
Fungal infection | 20.04 | 11.48 | 7 | 86040 | 13593 | 29852838 |
Confabulation | 19.95 | 11.48 | 9 | 86038 | 122 | 29866309 |
Upper respiratory tract infection | 19.93 | 11.48 | 30 | 86017 | 27446 | 29838985 |
Suicidal behaviour | 19.90 | 11.48 | 22 | 86025 | 1340 | 29865091 |
Clostridium difficile colitis | 19.82 | 11.48 | 6 | 86041 | 12762 | 29853669 |
Hyperthermia | 19.80 | 11.48 | 69 | 85978 | 10030 | 29856401 |
Brain injury | 19.77 | 11.48 | 47 | 86000 | 5501 | 29860930 |
Lymphocyte count increased | 19.70 | 11.48 | 30 | 86017 | 2512 | 29863919 |
Condition aggravated | 19.69 | 11.48 | 527 | 85520 | 137339 | 29729092 |
Abulia | 19.57 | 11.48 | 14 | 86033 | 476 | 29865955 |
Somnambulism | 19.56 | 11.48 | 34 | 86013 | 3180 | 29863251 |
Pancreatitis necrotising | 19.48 | 11.48 | 29 | 86018 | 2380 | 29864051 |
Blood thrombin increased | 19.42 | 11.48 | 4 | 86043 | 0 | 29866431 |
Affect lability | 19.31 | 11.48 | 35 | 86012 | 3383 | 29863048 |
Bone marrow failure | 19.29 | 11.48 | 35 | 86012 | 29750 | 29836681 |
Pyrexia | 19.21 | 11.48 | 673 | 85374 | 293816 | 29572615 |
Affective disorder | 19.07 | 11.48 | 33 | 86014 | 3075 | 29863356 |
Rash erythematous | 18.85 | 11.48 | 22 | 86025 | 22430 | 29844001 |
Respiration abnormal | 18.82 | 11.48 | 30 | 86017 | 2612 | 29863819 |
Globulins decreased | 18.82 | 11.48 | 10 | 86037 | 197 | 29866234 |
Major depression | 18.80 | 11.48 | 38 | 86009 | 3984 | 29862447 |
Depersonalisation/derealisation disorder | 18.66 | 11.48 | 14 | 86033 | 513 | 29865918 |
Skin ulcer | 18.65 | 11.48 | 16 | 86031 | 18833 | 29847598 |
Galactorrhoea | 18.60 | 11.48 | 12 | 86035 | 343 | 29866088 |
Gait disturbance | 18.57 | 11.48 | 310 | 85737 | 74467 | 29791964 |
Asocial behaviour | 18.45 | 11.48 | 7 | 86040 | 59 | 29866372 |
Flatulence | 18.42 | 11.48 | 15 | 86032 | 18114 | 29848317 |
Pain in jaw | 18.36 | 11.48 | 6 | 86041 | 12150 | 29854281 |
Laboratory test abnormal | 18.26 | 11.48 | 14 | 86033 | 17428 | 29849003 |
Proteinuria | 18.16 | 11.48 | 12 | 86035 | 16133 | 29850298 |
Soliloquy | 18.06 | 11.48 | 12 | 86035 | 361 | 29866070 |
Electrocardiogram QT shortened | 17.92 | 11.48 | 9 | 86038 | 157 | 29866274 |
Eosinophilia | 17.88 | 11.48 | 117 | 85930 | 22043 | 29844388 |
Bone pain | 17.81 | 11.48 | 17 | 86030 | 19009 | 29847422 |
Osteomyelitis | 17.79 | 11.48 | 10 | 86037 | 14671 | 29851760 |
Neoplasm malignant | 17.78 | 11.48 | 15 | 86032 | 17799 | 29848632 |
Anaphylactic shock | 17.74 | 11.48 | 9 | 86038 | 13984 | 29852447 |
Cerebral haemorrhage | 17.65 | 11.48 | 43 | 86004 | 32844 | 29833587 |
Alcohol abuse | 17.64 | 11.48 | 44 | 86003 | 5309 | 29861122 |
Dysphoria | 17.57 | 11.48 | 26 | 86021 | 2122 | 29864309 |
Sluggishness | 17.52 | 11.48 | 32 | 86015 | 3111 | 29863320 |
Squamous cell carcinoma | 17.47 | 11.48 | 4 | 86043 | 10246 | 29856185 |
Polydipsia psychogenic | 17.44 | 11.48 | 8 | 86039 | 113 | 29866318 |
Injection site erythema | 17.38 | 11.48 | 9 | 86038 | 13825 | 29852606 |
Embolism venous | 17.34 | 11.48 | 20 | 86027 | 1277 | 29865154 |
Blood bilirubin increased | 17.32 | 11.48 | 51 | 85996 | 36585 | 29829846 |
Hepatitis viral | 17.24 | 11.48 | 13 | 86034 | 480 | 29865951 |
Pulmonary valve incompetence | 17.21 | 11.48 | 15 | 86032 | 682 | 29865749 |
Multiple drug therapy | 17.17 | 11.48 | 10 | 86037 | 237 | 29866194 |
Vascular stenosis | 17.13 | 11.48 | 9 | 86038 | 173 | 29866258 |
Impaired healing | 17.04 | 11.48 | 10 | 86037 | 14330 | 29852101 |
Upper gastrointestinal haemorrhage | 17.01 | 11.48 | 23 | 86024 | 22005 | 29844426 |
Lens dislocation | 16.92 | 11.48 | 5 | 86042 | 17 | 29866414 |
Gastrointestinal hypermotility | 16.89 | 11.48 | 8 | 86039 | 122 | 29866309 |
Anger | 16.87 | 11.48 | 70 | 85977 | 11050 | 29855381 |
Snoring | 16.84 | 11.48 | 30 | 86017 | 2861 | 29863570 |
Head banging | 16.83 | 11.48 | 8 | 86039 | 123 | 29866308 |
Dyspraxia | 16.76 | 11.48 | 10 | 86037 | 248 | 29866183 |
Malaise | 16.72 | 11.48 | 359 | 85688 | 166603 | 29699828 |
Lipids increased | 16.69 | 11.48 | 17 | 86030 | 942 | 29865489 |
Sleep disorder | 16.67 | 11.48 | 124 | 85923 | 24355 | 29842076 |
Hyperosmolar state | 16.67 | 11.48 | 12 | 86035 | 412 | 29866019 |
Bladder cancer | 16.66 | 11.48 | 3 | 86044 | 9099 | 29857332 |
Parkinsonian rest tremor | 16.60 | 11.48 | 8 | 86039 | 127 | 29866304 |
Blister | 16.59 | 11.48 | 21 | 86026 | 20662 | 29845769 |
Myoglobin blood increased | 16.57 | 11.48 | 23 | 86024 | 1770 | 29864661 |
Drug ineffective | 16.54 | 11.48 | 1162 | 84885 | 339225 | 29527206 |
Glassy eyes | 16.50 | 11.48 | 7 | 86040 | 81 | 29866350 |
Blood creatine phosphokinase MB increased | 16.47 | 11.48 | 24 | 86023 | 1932 | 29864499 |
Movement disorder | 16.42 | 11.48 | 64 | 85983 | 9819 | 29856612 |
Cerebellar atrophy | 16.40 | 11.48 | 12 | 86035 | 423 | 29866008 |
Haemoptysis | 16.39 | 11.48 | 41 | 86006 | 31037 | 29835394 |
Cyclothymic disorder | 16.35 | 11.48 | 7 | 86040 | 83 | 29866348 |
Haemophagocytic lymphohistiocytosis | 16.33 | 11.48 | 4 | 86043 | 9787 | 29856644 |
Neglect of personal appearance | 16.33 | 11.48 | 8 | 86039 | 132 | 29866299 |
Ageusia | 16.28 | 11.48 | 3 | 86044 | 8950 | 29857481 |
Jaundice | 16.26 | 11.48 | 44 | 86003 | 32442 | 29833989 |
Lung disorder | 16.22 | 11.48 | 42 | 86005 | 31427 | 29835004 |
Myotonia | 16.20 | 11.48 | 6 | 86041 | 47 | 29866384 |
Faeces discoloured | 16.19 | 11.48 | 10 | 86037 | 13936 | 29852495 |
Ejaculation disorder | 16.10 | 11.48 | 17 | 86030 | 983 | 29865448 |
Vascular encephalopathy | 15.99 | 11.48 | 7 | 86040 | 88 | 29866343 |
Contusion | 15.93 | 11.48 | 42 | 86005 | 31238 | 29835193 |
Antisocial personality disorder | 15.91 | 11.48 | 5 | 86042 | 22 | 29866409 |
Rebound effect | 15.91 | 11.48 | 21 | 86026 | 1540 | 29864891 |
Gastrectomy | 15.90 | 11.48 | 8 | 86039 | 140 | 29866291 |
Motor dysfunction | 15.88 | 11.48 | 45 | 86002 | 5857 | 29860574 |
Generalised anxiety disorder | 15.85 | 11.48 | 14 | 86033 | 648 | 29865783 |
Paraphilia | 15.85 | 11.48 | 7 | 86040 | 90 | 29866341 |
Peritonitis | 15.83 | 11.48 | 23 | 86024 | 21352 | 29845079 |
Dry skin | 15.82 | 11.48 | 25 | 86022 | 22429 | 29844002 |
Selective mutism | 15.77 | 11.48 | 6 | 86041 | 51 | 29866380 |
Hostility | 15.76 | 11.48 | 16 | 86031 | 883 | 29865548 |
Abnormal weight gain | 15.65 | 11.48 | 16 | 86031 | 891 | 29865540 |
Pulmonary hypertension | 15.61 | 11.48 | 19 | 86028 | 19017 | 29847414 |
Drug use disorder | 15.55 | 11.48 | 31 | 86016 | 3217 | 29863214 |
Angina unstable | 15.48 | 11.48 | 8 | 86039 | 12302 | 29854129 |
Thrombotic microangiopathy | 15.41 | 11.48 | 3 | 86044 | 8607 | 29857824 |
Graft versus host disease | 15.35 | 11.48 | 5 | 86042 | 10145 | 29856286 |
Basophil count decreased | 15.19 | 11.48 | 7 | 86040 | 100 | 29866331 |
Treatment failure | 15.17 | 11.48 | 50 | 85997 | 34629 | 29831802 |
Cellulitis | 15.09 | 11.48 | 76 | 85971 | 46708 | 29819723 |
Secondary tic | 15.05 | 11.48 | 4 | 86043 | 8 | 29866423 |
Renal tubular necrosis | 15.02 | 11.48 | 13 | 86034 | 15238 | 29851193 |
Device related infection | 15.02 | 11.48 | 16 | 86031 | 16999 | 29849432 |
Thirst | 14.97 | 11.48 | 49 | 85998 | 6900 | 29859531 |
Paranoid personality disorder | 14.92 | 11.48 | 5 | 86042 | 28 | 29866403 |
Frequent bowel movements | 14.89 | 11.48 | 3 | 86044 | 8402 | 29858029 |
Epilepsy | 14.79 | 11.48 | 104 | 85943 | 20065 | 29846366 |
Mobility decreased | 14.74 | 11.48 | 33 | 86014 | 25966 | 29840465 |
Flushing | 14.72 | 11.48 | 40 | 86007 | 29452 | 29836979 |
Cholestasis | 14.70 | 11.48 | 31 | 86016 | 24919 | 29841512 |
Chromaturia | 14.68 | 11.48 | 11 | 86036 | 13854 | 29852577 |
Gastrointestinal sounds abnormal | 14.67 | 11.48 | 23 | 86024 | 1975 | 29864456 |
Hyperammonaemic encephalopathy | 14.62 | 11.48 | 22 | 86025 | 1822 | 29864609 |
Skin lesion | 14.60 | 11.48 | 19 | 86028 | 18475 | 29847956 |
Schizoid personality disorder | 14.57 | 11.48 | 3 | 86044 | 0 | 29866431 |
Hyperinsulinism | 14.49 | 11.48 | 6 | 86041 | 65 | 29866366 |
Tangentiality | 14.42 | 11.48 | 7 | 86040 | 113 | 29866318 |
Tic | 14.38 | 11.48 | 23 | 86024 | 2009 | 29864422 |
Trismus | 14.37 | 11.48 | 25 | 86022 | 2340 | 29864091 |
Electrocardiogram PR prolongation | 14.34 | 11.48 | 14 | 86033 | 737 | 29865694 |
Contraindicated product administered | 14.34 | 11.48 | 17 | 86030 | 17214 | 29849217 |
Wrong technique in product usage process | 14.27 | 11.48 | 44 | 86003 | 31111 | 29835320 |
Urinary retention | 14.25 | 11.48 | 151 | 85896 | 32766 | 29833665 |
Ventricular hypokinesia | 14.22 | 11.48 | 35 | 86012 | 4188 | 29862243 |
Metastases to bone | 14.18 | 11.48 | 5 | 86042 | 9653 | 29856778 |
Cataract congenital | 14.18 | 11.48 | 6 | 86041 | 69 | 29866362 |
Inflammation | 14.16 | 11.48 | 26 | 86021 | 22000 | 29844431 |
Chemical poisoning | 14.10 | 11.48 | 7 | 86040 | 119 | 29866312 |
Personality disorder | 14.09 | 11.48 | 17 | 86030 | 1138 | 29865293 |
Illusion | 14.08 | 11.48 | 14 | 86033 | 754 | 29865677 |
Diabetes insipidus | 14.04 | 11.48 | 24 | 86023 | 2215 | 29864216 |
Respiratory failure | 14.02 | 11.48 | 204 | 85843 | 100438 | 29765993 |
Pseudoporphyria | 13.90 | 11.48 | 9 | 86038 | 259 | 29866172 |
Reduced facial expression | 13.89 | 11.48 | 14 | 86033 | 766 | 29865665 |
Thought blocking | 13.89 | 11.48 | 7 | 86040 | 123 | 29866308 |
Glycosylated haemoglobin increased | 13.81 | 11.48 | 59 | 85988 | 9432 | 29856999 |
Gynaecomastia | 13.81 | 11.48 | 54 | 85993 | 8297 | 29858134 |
Incontinence | 13.74 | 11.48 | 40 | 86007 | 5286 | 29861145 |
Oral pain | 13.74 | 11.48 | 5 | 86042 | 9464 | 29856967 |
Posterior reversible encephalopathy syndrome | 13.68 | 11.48 | 4 | 86043 | 8703 | 29857728 |
Mixed delusion | 13.67 | 11.48 | 4 | 86043 | 13 | 29866418 |
Eczema | 13.66 | 11.48 | 11 | 86036 | 13358 | 29853073 |
Coordination abnormal | 13.54 | 11.48 | 49 | 85998 | 7256 | 29859175 |
Blood cholesterol abnormal | 13.53 | 11.48 | 18 | 86029 | 1330 | 29865101 |
Joint stiffness | 13.48 | 11.48 | 5 | 86042 | 9356 | 29857075 |
Pancreatic carcinoma | 13.47 | 11.48 | 3 | 86044 | 7834 | 29858597 |
Echolalia | 13.42 | 11.48 | 8 | 86039 | 198 | 29866233 |
Tricuspid valve sclerosis | 13.41 | 11.48 | 5 | 86042 | 40 | 29866391 |
Resting tremor | 13.32 | 11.48 | 12 | 86035 | 570 | 29865861 |
Strabismus congenital | 13.30 | 11.48 | 5 | 86042 | 41 | 29866390 |
Intestinal perforation | 13.23 | 11.48 | 4 | 86043 | 8515 | 29857916 |
Oropharyngeal pain | 13.23 | 11.48 | 40 | 86007 | 28456 | 29837975 |
Hypotonia | 13.22 | 11.48 | 47 | 86000 | 6901 | 29859530 |
Blood cholesterol decreased | 13.18 | 11.48 | 15 | 86032 | 944 | 29865487 |
Foetal arrhythmia | 13.06 | 11.48 | 6 | 86041 | 85 | 29866346 |
Blood creatine phosphokinase decreased | 13.04 | 11.48 | 11 | 86036 | 478 | 29865953 |
Rash maculo-papular | 13.04 | 11.48 | 34 | 86013 | 25384 | 29841047 |
Pathogen resistance | 12.97 | 11.48 | 4 | 86043 | 8406 | 29858025 |
Blood loss anaemia | 12.95 | 11.48 | 3 | 86044 | 7624 | 29858807 |
Neuralgia | 12.87 | 11.48 | 7 | 86040 | 10459 | 29855972 |
Substance abuse | 12.86 | 11.48 | 47 | 86000 | 6993 | 29859438 |
Drug eruption | 12.84 | 11.48 | 19 | 86028 | 17507 | 29848924 |
Acetonaemia | 12.82 | 11.48 | 6 | 86041 | 89 | 29866342 |
Disseminated intravascular coagulation | 12.69 | 11.48 | 28 | 86019 | 22143 | 29844288 |
Cardiogenic shock | 12.63 | 11.48 | 18 | 86029 | 16843 | 29849588 |
Transfusion | 12.54 | 11.48 | 3 | 86044 | 7458 | 29858973 |
Seizure | 12.53 | 11.48 | 371 | 85676 | 98104 | 29768327 |
Glutamate dehydrogenase increased | 12.50 | 11.48 | 3 | 86044 | 3 | 29866428 |
Inferiority complex | 12.50 | 11.48 | 3 | 86044 | 3 | 29866428 |
Oliguria | 12.48 | 11.48 | 3 | 86044 | 7436 | 29858995 |
Velopharyngeal incompetence | 12.48 | 11.48 | 4 | 86043 | 19 | 29866412 |
Malignant melanoma | 12.41 | 11.48 | 3 | 86044 | 7408 | 29859023 |
Hypoaesthesia | 12.38 | 11.48 | 98 | 85949 | 54132 | 29812299 |
Haemorrhage intracranial | 12.33 | 11.48 | 15 | 86032 | 15017 | 29851414 |
Ear infection | 12.32 | 11.48 | 3 | 86044 | 7371 | 29859060 |
Eyelid bleeding | 12.31 | 11.48 | 4 | 86043 | 20 | 29866411 |
Retrognathia | 12.30 | 11.48 | 8 | 86039 | 232 | 29866199 |
Rectal haemorrhage | 12.30 | 11.48 | 55 | 85992 | 34884 | 29831547 |
Family stress | 12.28 | 11.48 | 7 | 86040 | 159 | 29866272 |
Paradoxical drug reaction | 12.26 | 11.48 | 25 | 86022 | 2637 | 29863794 |
Injection site bruising | 12.23 | 11.48 | 3 | 86044 | 7335 | 29859096 |
Myelosuppression | 12.19 | 11.48 | 3 | 86044 | 7319 | 29859112 |
Drug withdrawal syndrome | 12.19 | 11.48 | 98 | 85949 | 19711 | 29846720 |
Hypomagnesaemia | 12.15 | 11.48 | 18 | 86029 | 16580 | 29849851 |
Pharyngeal dyskinesia | 12.15 | 11.48 | 4 | 86043 | 21 | 29866410 |
Cataract | 12.15 | 11.48 | 28 | 86019 | 21807 | 29844624 |
Gastric haemorrhage | 12.13 | 11.48 | 6 | 86041 | 9461 | 29856970 |
Hypokinesia | 12.05 | 11.48 | 47 | 86000 | 7213 | 29859218 |
Tachyphrenia | 12.01 | 11.48 | 15 | 86032 | 1041 | 29865390 |
Antidepressant drug level increased | 11.98 | 11.48 | 6 | 86041 | 104 | 29866327 |
Sexually inappropriate behaviour | 11.96 | 11.48 | 9 | 86038 | 331 | 29866100 |
Erythema multiforme | 11.96 | 11.48 | 4 | 86043 | 7981 | 29858450 |
Osteoporosis | 11.90 | 11.48 | 8 | 86039 | 10655 | 29855776 |
Dextrocardia | 11.86 | 11.48 | 7 | 86040 | 170 | 29866261 |
Encephalitis autoimmune | 11.83 | 11.48 | 10 | 86037 | 436 | 29865995 |
Helplessness | 11.78 | 11.48 | 5 | 86042 | 58 | 29866373 |
Foetal heart rate abnormal | 11.76 | 11.48 | 7 | 86040 | 173 | 29866258 |
Cardiac septal hypertrophy | 11.75 | 11.48 | 8 | 86039 | 251 | 29866180 |
Chest pain | 11.74 | 11.48 | 253 | 85794 | 117374 | 29749057 |
Breathing-related sleep disorder | 11.72 | 11.48 | 7 | 86040 | 174 | 29866257 |
Phlebitis superficial | 11.72 | 11.48 | 8 | 86039 | 252 | 29866179 |
Blood creatine decreased | 11.70 | 11.48 | 5 | 86042 | 59 | 29866372 |
Drug level decreased | 11.68 | 11.48 | 40 | 86007 | 5765 | 29860666 |
Clumsiness | 11.65 | 11.48 | 17 | 86030 | 1370 | 29865061 |
Negative thoughts | 11.58 | 11.48 | 12 | 86035 | 679 | 29865752 |
Platelet count decreased | 11.56 | 11.48 | 225 | 85822 | 105904 | 29760527 |
Cholangitis | 11.52 | 11.48 | 4 | 86043 | 7798 | 29858633 |
Pseudomonas infection | 11.51 | 11.48 | 8 | 86039 | 10474 | 29855957 |
Source | Code | Description |
---|---|---|
ATC | N05AH03 | NERVOUS SYSTEM PSYCHOLEPTICS ANTIPSYCHOTICS Diazepines, oxazepines, thiazepines and oxepines |
FDA EPC | N0000175430 | Atypical Antipsychotic |
MeSH PA | D000932 | Antiemetics |
MeSH PA | D014150 | Antipsychotic Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D005765 | Gastrointestinal Agents |
MeSH PA | D049990 | Membrane Transport Modulators |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D014179 | Neurotransmitter Uptake Inhibitors |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D011619 | Psychotropic Drugs |
MeSH PA | D018490 | Serotonin Agents |
MeSH PA | D017367 | Serotonin Uptake Inhibitors |
MeSH PA | D014149 | Tranquilizing Agents |
CHEBI has role | CHEBI:37956 | histamine receptor blocker |
CHEBI has role | CHEBI:48279 | serotonin antagonists |
CHEBI has role | CHEBI:48561 | dopamine blocker |
CHEBI has role | CHEBI:48876 | antimuskarinika |
CHEBI has role | CHEBI:50919 | antiemetico |
CHEBI has role | CHEBI:50949 | serotonin reuptake inhibitor |
CHEBI has role | CHEBI:65191 | atypical antipsychotics |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Mixed bipolar I disorder | indication | 16506000 | DOID:3312 |
Schizophrenia | indication | 58214004 | DOID:5419 |
Bipolar disorder in remission | indication | 85248005 | |
Bipolar affective disorder, current episode manic | indication | 191618007 | |
Bipolar affective disorder, current episode depression | indication | 191627008 | DOID:3312 |
Major depressive disorder | indication | 370143000 | |
Depression Treatment Adjunct | indication | ||
Agitation associated with Bipolar Mania | indication | ||
Agitation associated with Schizophrenia | indication | ||
Nausea and vomiting | off-label use | 16932000 | |
Feeling agitated | off-label use | 24199005 | |
Migraine | off-label use | 37796009 | DOID:6364 |
Insomnia | off-label use | 193462001 | |
Anxiety disorder | off-label use | 197480006 | DOID:2030 |
Chemotherapy-induced nausea and vomiting | off-label use | 236084000 | |
cannabinoid hyperememsis | off-label use | 11047881000119100 | |
cannabinoid hyperememsis | off-label use | 11048011000119100 | |
Delirium | contraindication | 2776000 | |
Suicidal thoughts | contraindication | 6471006 | |
Weight gain finding | contraindication | 8943002 | |
Sinus tachycardia | contraindication | 11092001 | |
Hypercholesterolemia | contraindication | 13644009 | |
Bipolar disorder | contraindication | 13746004 | DOID:3312 |
Neuroleptic malignant syndrome | contraindication | 15244003 | DOID:14464 |
Senile dementia | contraindication | 15662003 | |
Agranulocytosis | contraindication | 17182001 | DOID:12987 |
Lowered convulsive threshold | contraindication | 19260006 | |
Cirrhosis of liver | contraindication | 19943007 | DOID:5082 |
Myocardial infarction | contraindication | 22298006 | DOID:5844 |
Hypovolemia | contraindication | 28560003 | |
Orthostatic hypotension | contraindication | 28651003 | |
Dehydration | contraindication | 34095006 | |
Upper gastrointestinal hemorrhage | contraindication | 37372002 | |
Conduction disorder of the heart | contraindication | 44808001 | |
Low blood pressure | contraindication | 45007003 | |
Bradycardia | contraindication | 48867003 | |
Syndrome of inappropriate vasopressin secretion | contraindication | 55004003 | DOID:3401 |
Paralytic ileus | contraindication | 55525008 | DOID:8442 |
Hyperlipidemia | contraindication | 55822004 | DOID:1168 |
Anorexia nervosa | contraindication | 56882008 | DOID:8689 |
Abnormal sexual function | contraindication | 56925008 | |
Hepatic failure | contraindication | 59927004 | |
Cerebrovascular disease | contraindication | 62914000 | DOID:6713 |
Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
Sedation | contraindication | 72641008 | |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Hyperglycemia | contraindication | 80394007 | DOID:4195 |
Heart failure | contraindication | 84114007 | DOID:6000 |
Epilepsy | contraindication | 84757009 | DOID:1826 |
Leukopenia | contraindication | 84828003 | DOID:615 |
Hyponatremia | contraindication | 89627008 | |
Tardive dyskinesia | contraindication | 102449007 | |
Seizure disorder | contraindication | 128613002 | |
Liver function tests abnormal | contraindication | 166603001 | |
Cerebrovascular accident | contraindication | 230690007 | |
Mania | contraindication | 231494001 | |
Hypomania | contraindication | 231496004 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Metabolic syndrome X | contraindication | 237602007 | DOID:14221 |
Hyperprolactinemia | contraindication | 237662005 | DOID:12700 |
Transient ischemic attack | contraindication | 266257000 | DOID:224 |
Esophageal dysmotility | contraindication | 266434009 | DOID:9192 |
Benign prostatic hyperplasia | contraindication | 266569009 | |
Hypertriglyceridemia | contraindication | 302870006 | |
Neutropenic disorder | contraindication | 303011007 | DOID:1227 |
Serotonin syndrome | contraindication | 371089000 | |
Coma | contraindication | 371632003 | |
At risk for aspiration | contraindication | 371736008 | |
Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
Myocardial ischemia | contraindication | 414795007 | DOID:3393 |
Obesity | contraindication | 414916001 | DOID:9970 |
Carcinoma of female breast | contraindication | 447782002 | |
Smokes tobacco daily | contraindication | 449868002 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 7.59 | Basic |
pKa2 | 5.72 | Basic |
pKa3 | 0.66 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A | GPCR | ANTAGONIST | Ki | 8.32 | WOMBAT-PK | CHEMBL | |||
D(2) dopamine receptor | GPCR | ANTAGONIST | Ki | 8.52 | WOMBAT-PK | CHEMBL | |||
D(4) dopamine receptor | GPCR | ANTAGONIST | Ki | 8.80 | WOMBAT-PK | ||||
5-hydroxytryptamine receptor 1E | GPCR | AGONIST | Ki | 5.70 | IUPHAR | ||||
Sodium-dependent serotonin transporter | Transporter | Ki | 6.26 | DRUG MATRIX | |||||
Alpha-1D adrenergic receptor | GPCR | Ki | 7.59 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 1A | GPCR | Kd | 5.90 | CHEMBL | |||||
D(3) dopamine receptor | GPCR | ANTAGONIST | Ki | 8.10 | WOMBAT-PK | ||||
5-hydroxytryptamine receptor 2C | GPCR | ANTAGONIST | Ki | 7.96 | WOMBAT-PK | ||||
5-hydroxytryptamine receptor 1F | GPCR | Ki | 6.51 | WOMBAT-PK | |||||
Alpha-1B adrenergic receptor | GPCR | Ki | 6.58 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 3A | Ion channel | Ki | 6.69 | WOMBAT-PK | |||||
Alpha-2C adrenergic receptor | GPCR | Ki | 7.54 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 1D | GPCR | Ki | 6.12 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 1B | GPCR | Ki | 6.23 | WOMBAT-PK | |||||
Aldehyde oxidase | Enzyme | IC50 | 5.22 | WOMBAT-PK | |||||
Muscarinic acetylcholine receptor M5 | GPCR | Ki | 8.05 | WOMBAT-PK | |||||
Muscarinic acetylcholine receptor M4 | GPCR | Ki | 7.68 | WOMBAT-PK | |||||
Muscarinic acetylcholine receptor M3 | GPCR | Ki | 7.14 | WOMBAT-PK | |||||
Muscarinic acetylcholine receptor M2 | GPCR | Ki | 7.10 | WOMBAT-PK | |||||
Muscarinic acetylcholine receptor M1 | GPCR | Ki | 7.51 | WOMBAT-PK | |||||
Histamine H2 receptor | GPCR | Ki | 7.36 | WOMBAT-PK | |||||
Histamine H1 receptor | GPCR | Ki | 8.15 | WOMBAT-PK | |||||
D(1B) dopamine receptor | GPCR | Ki | 7.05 | WOMBAT-PK | |||||
Alpha-2B adrenergic receptor | GPCR | Ki | 7.09 | WOMBAT-PK | |||||
Alpha-1A adrenergic receptor | GPCR | Ki | 7.72 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 7 | GPCR | Ki | 6.98 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 6 | GPCR | Ki | 8.10 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 2B | GPCR | Ki | 7.92 | WOMBAT-PK | |||||
Potassium voltage-gated channel subfamily H member 2 | Ion channel | IC50 | 6.74 | WOMBAT-PK | |||||
Alpha-2A adrenergic receptor | GPCR | Ki | 6.49 | WOMBAT-PK | |||||
D(1A) dopamine receptor | GPCR | Ki | 7.40 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 5A | GPCR | Ki | 5.92 | PDSP | |||||
Beta-2 adrenergic receptor | GPCR | Ki | 5.30 | PDSP | |||||
Beta-1 adrenergic receptor | GPCR | Ki | 5.30 | PDSP | |||||
FAD-linked sulfhydryl oxidase ALR | Enzyme | AC50 | 6.43 | CHEMBL | |||||
Arachidonate 15-lipoxygenase | Enzyme | IC50 | 5.56 | DRUG MATRIX | |||||
Alpha-1B adrenergic receptor | GPCR | Ki | 7.68 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 1B | GPCR | Ki | 6.36 | DRUG MATRIX | |||||
Transporter | Transporter | Ki | 5.70 | CHEMBL | |||||
Transporter | Transporter | Ki | 6.02 | CHEMBL | |||||
D(3) dopamine receptor | GPCR | Ki | 7.41 | CHEMBL | |||||
Serotonin 2 (5-HT2) receptor | GPCR | Ki | 7.92 | CHEMBL | |||||
Adrenergic receptor alpha-2 | GPCR | Ki | 5.54 | CHEMBL | |||||
Muscarinic acetylcholine receptor M1 | GPCR | Ki | 7.66 | CHEMBL | |||||
5-hydroxytryptamine receptor 1A | GPCR | Ki | 6.21 | CHEMBL | |||||
D(1A) dopamine receptor | GPCR | Ki | 7.70 | CHEMBL | |||||
Histamine H1 receptor | GPCR | Ki | 9.52 | CHEMBL | |||||
D(2) dopamine receptor | GPCR | Ki | 7.90 | CHEMBL | |||||
5-hydroxytryptamine receptor 2A | GPCR | Ki | 8.40 | CHEMBL | |||||
Histamine H1 receptor | GPCR | Ki | 8.20 | CHEMBL | |||||
D(4) dopamine receptor | GPCR | Ki | 7.30 | CHEMBL | |||||
5-hydroxytryptamine receptor 6 | GPCR | ANTAGONIST | Ki | 8.60 | IUPHAR | ||||
Alpha-1A adrenergic receptor | GPCR | IC50 | 7.19 | CHEMBL | |||||
5-hydroxytryptamine receptor 7 | GPCR | ANTAGONIST | Ki | 7 | IUPHAR |
ID | Source |
---|---|
4020996 | VUID |
N0000148465 | NUI |
D00454 | KEGG_DRUG |
221373-18-8 | SECONDARY_CAS_RN |
4020996 | VANDF |
C0171021 | UMLSCUI |
CHEBI:7735 | CHEBI |
CHEMBL715 | ChEMBL_ID |
CHEMBL3989694 | ChEMBL_ID |
CHEMBL1201741 | ChEMBL_ID |
D000077152 | MESH_DESCRIPTOR_UI |
DB00334 | DRUGBANK_ID |
47 | IUPHAR_LIGAND_ID |
6956 | INN_ID |
N7U69T4SZR | UNII |
135398745 | PUBCHEM_CID |
1294588 | RXNORM |
169390 | MMSL |
172501 | MMSL |
5198 | MMSL |
6063 | MMSL |
d04050 | MMSL |
006204 | NDDF |
013309 | NDDF |
108441004 | SNOMEDCT_US |
386849001 | SNOMEDCT_US |
725800004 | SNOMEDCT_US |
735189005 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Symbyax | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0002-3230 | CAPSULE | 3 mg | ORAL | NDA | 34 sections |
Symbyax | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0002-3231 | CAPSULE | 6 mg | ORAL | NDA | 34 sections |
Symbyax | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0002-3232 | CAPSULE | 12 mg | ORAL | NDA | 34 sections |
Symbyax | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0002-3233 | CAPSULE | 6 mg | ORAL | NDA | 34 sections |
Symbyax | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0002-3234 | CAPSULE | 12 mg | ORAL | NDA | 34 sections |
Zyprexa | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4112 | TABLET | 2.50 mg | ORAL | NDA | 36 sections |
Zyprexa | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4115 | TABLET | 5 mg | ORAL | NDA | 36 sections |
Zyprexa | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4116 | TABLET | 7.50 mg | ORAL | NDA | 36 sections |
Zyprexa | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4117 | TABLET | 10 mg | ORAL | NDA | 36 sections |
Zyprexa | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4415 | TABLET | 15 mg | ORAL | NDA | 36 sections |
Zyprexa | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4420 | TABLET | 20 mg | ORAL | NDA | 36 sections |
ZYPREXA Zydis | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4453 | TABLET, ORALLY DISINTEGRATING | 5 mg | ORAL | NDA | 36 sections |
ZYPREXA Zydis | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4454 | TABLET, ORALLY DISINTEGRATING | 10 mg | ORAL | NDA | 36 sections |
ZYPREXA Zydis | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4455 | TABLET, ORALLY DISINTEGRATING | 15 mg | ORAL | NDA | 36 sections |
ZYPREXA Zydis | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-4456 | TABLET, ORALLY DISINTEGRATING | 20 mg | ORAL | NDA | 36 sections |
ZYPREXA Intramuscular | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0002-7597 | INJECTION, POWDER, FOR SOLUTION | 10 mg | INTRAMUSCULAR | NDA | 36 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-5245 | TABLET, ORALLY DISINTEGRATING | 5 mg | ORAL | ANDA | 31 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-5246 | TABLET, ORALLY DISINTEGRATING | 10 mg | ORAL | ANDA | 31 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-5247 | TABLET, ORALLY DISINTEGRATING | 15 mg | ORAL | ANDA | 31 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-5248 | TABLET, ORALLY DISINTEGRATING | 20 mg | ORAL | ANDA | 31 sections |
Olanzapine and Fluoxetine | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0093-5503 | CAPSULE | 3 mg | ORAL | ANDA | 32 sections |
Olanzapine and Fluoxetine | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0093-5504 | CAPSULE | 6 mg | ORAL | ANDA | 32 sections |
Olanzapine and Fluoxetine | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0093-5505 | CAPSULE | 6 mg | ORAL | ANDA | 32 sections |
Olanzapine and Fluoxetine | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0093-5506 | CAPSULE | 12 mg | ORAL | ANDA | 32 sections |
Olanzapine and Fluoxetine | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0093-5507 | CAPSULE | 12 mg | ORAL | ANDA | 32 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-5510 | TABLET, ORALLY DISINTEGRATING | 5 mg | ORAL | ANDA | 34 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-5511 | TABLET, ORALLY DISINTEGRATING | 10 mg | ORAL | ANDA | 34 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-5512 | TABLET, ORALLY DISINTEGRATING | 15 mg | ORAL | ANDA | 34 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-5513 | TABLET, ORALLY DISINTEGRATING | 20 mg | ORAL | ANDA | 34 sections |
Olanzapine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0517-0955 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 10 mg | INTRAMUSCULAR | ANDA | 31 sections |