norfenefrine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
sympathomimetic, phenethyl derivatives	1966	536-21-0

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

norfenefrine
DL-Norphenylephrine
metacardiol
metaoctopamine
normetasympathol
normetasynephrine
normezaton
norphenephrine
norphenylephrine
norfenefrine hydrochloride
norfenefrine HCl

Molecular weight: 153.18
Formula: C8H11NO2
CLOGP: -0.39
LIPINSKI: 0
HAC: 3
HDO: 3
TPSA: 66.48
ALOGS: -0.91
ROTB: 2

Drug dosage:

Dose	Unit	Route
25	mg	O

ADMET properties:

Property	Value	Reference
BA (Bioavailability)	5 %	Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	C01CA05	CARDIOVASCULAR SYSTEM CARDIAC THERAPY CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES Adrenergic and dopaminergic agents
MeSH PA	D018663	Adrenergic Agents
MeSH PA	D000322	Adrenergic Agonists
MeSH PA	D000316	Adrenergic alpha-Agonists
MeSH PA	D018377	Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.59	acidic
pKa2	12.35	acidic
pKa3	8.83	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D01405	KEGG_DRUG
C0068986	UMLSCUI
CHEBI:134779	CHEBI
CHEMBL358040	ChEMBL_ID
DB13378	DRUGBANK_ID
4538	PUBCHEM_CID
2140	INN_ID
C005310	MESH_SUPPLEMENTAL_RECORD_UI
4779-94-6	SECONDARY_CAS_RN
D2P3M6SRN5	UNII
236468	RXNORM
006039	NDDF
006040	NDDF
96256004	SNOMEDCT_US

Pharmaceutical products:

None