loperamide oxide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1600 106900-12-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • loperamide oxide monohydrate
  • loperamide oxide
  • arestal
  • Molecular weight: 493.04
  • Formula: C29H33ClN2O3
  • CLOGP: 2.62
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 63.60
  • ALOGS: -6.35
  • ROTB: 7

Drug dosage:

DoseUnitRoute
5 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Mydriasis 47.30 43.33 11 244 17632 79726501

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A07DA05 ALIMENTARY TRACT AND METABOLISM
ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
ANTIPROPULSIVES
Antipropulsives
MeSH PA D000930 Antidiarrheals
MeSH PA D005765 Gastrointestinal Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.12 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07113 KEGG_DRUG
C0083256 UMLSCUI
CHEBI:135795 CHEBI
CHEMBL2105114 ChEMBL_ID
DB14661 DRUGBANK_ID
C066043 MESH_SUPPLEMENTAL_RECORD_UI
6139 INN_ID
NG66S4H2RL UNII
71421 PUBCHEM_CID
007968 NDDF
1269134006 SNOMEDCT_US
735074004 SNOMEDCT_US

Pharmaceutical products:

None