Stem definition | Drug id | CAS RN |
---|---|---|
1523 | 6740-88-1 |
None
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 200 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 4 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 8.41 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 20 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 2.90 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 19 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.47 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 2.80 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Feb. 19, 1970 | FDA | PAR STERILE PRODUCTS |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Anaphylactic shock | 439.12 | 20.46 | 159 | 8634 | 20115 | 46657154 |
Status epilepticus | 136.70 | 20.46 | 62 | 8731 | 13917 | 46663352 |
Dilatation intrahepatic duct acquired | 136.08 | 20.46 | 31 | 8762 | 725 | 46676544 |
Bronchospasm | 129.79 | 20.46 | 62 | 8731 | 15645 | 46661624 |
Propofol infusion syndrome | 129.73 | 20.46 | 30 | 8763 | 751 | 46676518 |
Hydronephrosis | 103.28 | 20.46 | 44 | 8749 | 8501 | 46668768 |
Mitochondrial DNULL mutation | 101.02 | 20.46 | 20 | 8773 | 231 | 46677038 |
Biliary dilatation | 95.67 | 20.46 | 29 | 8764 | 2095 | 46675174 |
Drug abuse | 94.06 | 20.46 | 85 | 8708 | 63323 | 46613946 |
Respiratory depression | 90.40 | 20.46 | 44 | 8749 | 11556 | 46665713 |
Intra-abdominal pressure increased | 85.34 | 20.46 | 17 | 8776 | 203 | 46677066 |
Delirium | 82.51 | 20.46 | 63 | 8730 | 37165 | 46640104 |
Sterile pyuria | 81.21 | 20.46 | 12 | 8781 | 15 | 46677254 |
Hypercapnia | 80.65 | 20.46 | 31 | 8762 | 4595 | 46672674 |
Pneumatosis | 79.37 | 20.46 | 18 | 8775 | 412 | 46676857 |
Hypotension | 77.84 | 20.46 | 149 | 8644 | 232440 | 46444829 |
Reduced bladder capacity | 75.78 | 20.46 | 10 | 8783 | 0 | 46677269 |
Blood lactic acid increased | 74.61 | 20.46 | 31 | 8762 | 5626 | 46671643 |
Drug ineffective for unapproved indication | 73.39 | 20.46 | 43 | 8750 | 16370 | 46660899 |
Body tinea | 70.14 | 20.46 | 19 | 8774 | 916 | 46676353 |
Blood pH decreased | 69.69 | 20.46 | 24 | 8769 | 2603 | 46674666 |
Unwanted awareness during anaesthesia | 68.99 | 20.46 | 15 | 8778 | 281 | 46676988 |
Gene mutation | 67.43 | 20.46 | 19 | 8774 | 1061 | 46676208 |
Cardiac arrest | 67.35 | 20.46 | 84 | 8709 | 90315 | 46586954 |
Blood gases abnormal | 67.32 | 20.46 | 17 | 8776 | 621 | 46676648 |
Haematuria | 65.17 | 20.46 | 48 | 8745 | 26810 | 46650459 |
Necrosis ischaemic | 62.58 | 20.46 | 17 | 8776 | 828 | 46676441 |
Hyperaesthesia | 61.81 | 20.46 | 30 | 8763 | 7826 | 46669443 |
Cystitis ulcerative | 60.62 | 20.46 | 8 | 8785 | 0 | 46677269 |
Shock | 59.77 | 20.46 | 42 | 8751 | 21803 | 46655466 |
Intestinal ischaemia | 59.21 | 20.46 | 28 | 8765 | 6897 | 46670372 |
Cardio-respiratory arrest | 56.82 | 20.46 | 63 | 8730 | 59806 | 46617463 |
Inhibitory drug interaction | 55.94 | 20.46 | 19 | 8774 | 1976 | 46675293 |
Venoocclusive liver disease | 55.06 | 20.46 | 23 | 8770 | 4228 | 46673041 |
Local anaesthetic systemic toxicity | 54.78 | 20.46 | 13 | 8780 | 365 | 46676904 |
Infection susceptibility increased | 54.30 | 20.46 | 19 | 8774 | 2160 | 46675109 |
Impaired quality of life | 53.93 | 20.46 | 21 | 8772 | 3221 | 46674048 |
Airway peak pressure increased | 52.53 | 20.46 | 12 | 8781 | 284 | 46676985 |
Lower urinary tract symptoms | 51.14 | 20.46 | 9 | 8784 | 51 | 46677218 |
Arthralgia | 50.80 | 20.46 | 5 | 8788 | 364598 | 46312671 |
Bladder hypertrophy | 50.35 | 20.46 | 11 | 8782 | 211 | 46677058 |
Respiratory acidosis | 49.94 | 20.46 | 24 | 8769 | 6124 | 46671145 |
Lung hyperinflation | 48.55 | 20.46 | 15 | 8778 | 1154 | 46676115 |
Multiple-drug resistance | 47.62 | 20.46 | 18 | 8775 | 2547 | 46674722 |
PCO2 increased | 47.52 | 20.46 | 15 | 8778 | 1239 | 46676030 |
Off label use | 46.64 | 20.46 | 167 | 8626 | 379674 | 46297595 |
Anaphylactic reaction | 45.48 | 20.46 | 53 | 8740 | 53059 | 46624210 |
Drug ineffective | 43.83 | 20.46 | 246 | 8547 | 677592 | 45999677 |
Systemic inflammatory response syndrome | 43.73 | 20.46 | 21 | 8772 | 5350 | 46671919 |
Anaphylactoid shock | 41.66 | 20.46 | 10 | 8783 | 295 | 46676974 |
Hallucination | 41.36 | 20.46 | 49 | 8744 | 49902 | 46627367 |
Contracted bladder | 41.31 | 20.46 | 6 | 8787 | 6 | 46677263 |
PO2 decreased | 40.74 | 20.46 | 14 | 8779 | 1508 | 46675761 |
Tonic clonic movements | 40.21 | 20.46 | 13 | 8780 | 1159 | 46676110 |
Hepatotoxicity | 39.96 | 20.46 | 35 | 8758 | 24974 | 46652295 |
Glucose tolerance impaired | 39.67 | 20.46 | 19 | 8774 | 4812 | 46672457 |
Agitation | 38.86 | 20.46 | 50 | 8743 | 55365 | 46621904 |
Ureteral polyp | 37.89 | 20.46 | 5 | 8788 | 0 | 46677269 |
Dysphoria | 37.53 | 20.46 | 18 | 8775 | 4571 | 46672698 |
Oesophageal spasm | 37.08 | 20.46 | 14 | 8779 | 1975 | 46675294 |
Hepatocellular injury | 36.86 | 20.46 | 36 | 8757 | 29486 | 46647783 |
Infantile apnoea | 36.68 | 20.46 | 11 | 8782 | 765 | 46676504 |
Ultrasound ovary abnormal | 35.42 | 20.46 | 7 | 8786 | 80 | 46677189 |
Metabolic acidosis | 35.38 | 20.46 | 40 | 8753 | 38740 | 46638529 |
Blood bicarbonate decreased | 35.33 | 20.46 | 15 | 8778 | 2870 | 46674399 |
Diastolic hypotension | 35.18 | 20.46 | 7 | 8786 | 83 | 46677186 |
Status asthmaticus | 34.65 | 20.46 | 11 | 8782 | 925 | 46676344 |
Cystitis interstitial | 34.58 | 20.46 | 12 | 8781 | 1330 | 46675939 |
Intensive care unit acquired weakness | 34.29 | 20.46 | 10 | 8783 | 631 | 46676638 |
Rheumatoid arthritis | 34.20 | 20.46 | 3 | 8790 | 240212 | 46437057 |
Foetal growth restriction | 34.16 | 20.46 | 19 | 8774 | 6548 | 46670721 |
Perforation | 34.08 | 20.46 | 11 | 8782 | 976 | 46676293 |
Drug tolerance | 33.75 | 20.46 | 15 | 8778 | 3203 | 46674066 |
Oesophageal pain | 33.74 | 20.46 | 14 | 8779 | 2529 | 46674740 |
Bladder disorder | 32.83 | 20.46 | 19 | 8774 | 7059 | 46670210 |
Headache | 32.02 | 20.46 | 26 | 8767 | 478326 | 46198943 |
Bladder necrosis | 31.77 | 20.46 | 5 | 8788 | 12 | 46677257 |
Mucocutaneous haemorrhage | 31.66 | 20.46 | 6 | 8787 | 54 | 46677215 |
Impaired work ability | 31.58 | 20.46 | 23 | 8770 | 12613 | 46664656 |
Nausea | 31.32 | 20.46 | 51 | 8742 | 687403 | 45989866 |
Post procedural stroke | 31.18 | 20.46 | 6 | 8787 | 59 | 46677210 |
Diarrhoea | 31.00 | 20.46 | 36 | 8757 | 559566 | 46117703 |
Drug interaction | 30.78 | 20.46 | 96 | 8697 | 202998 | 46474271 |
Sedation | 30.60 | 20.46 | 29 | 8764 | 22881 | 46654388 |
Ureteric stenosis | 30.15 | 20.46 | 9 | 8784 | 616 | 46676653 |
Poor quality sleep | 29.85 | 20.46 | 24 | 8769 | 15229 | 46662040 |
Biliary tract disorder | 29.20 | 20.46 | 9 | 8784 | 687 | 46676582 |
Oliguria | 29.10 | 20.46 | 19 | 8774 | 8740 | 46668529 |
Stress cardiomyopathy | 28.62 | 20.46 | 18 | 8775 | 7766 | 46669503 |
Cholestasis | 28.47 | 20.46 | 30 | 8763 | 26863 | 46650406 |
Circulatory collapse | 28.17 | 20.46 | 27 | 8766 | 21597 | 46655672 |
Reversible cerebral vasoconstriction syndrome | 28.13 | 20.46 | 11 | 8782 | 1706 | 46675563 |
Tachyphylaxis | 28.12 | 20.46 | 7 | 8786 | 241 | 46677028 |
Cystitis | 27.87 | 20.46 | 37 | 8756 | 42204 | 46635065 |
Oxygen saturation decreased | 27.70 | 20.46 | 48 | 8745 | 69116 | 46608153 |
Left ventricular hypertrophy | 27.58 | 20.46 | 15 | 8778 | 4948 | 46672321 |
Bone density decreased | 27.25 | 20.46 | 19 | 8774 | 9733 | 46667536 |
Intensive care unit delirium | 26.91 | 20.46 | 5 | 8788 | 40 | 46677229 |
Purpura | 26.89 | 20.46 | 19 | 8774 | 9939 | 46667330 |
Cyanosis | 26.82 | 20.46 | 23 | 8770 | 15948 | 46661321 |
Blood creatine phosphokinase increased | 25.97 | 20.46 | 29 | 8764 | 27695 | 46649574 |
Depersonalisation/derealisation disorder | 25.91 | 20.46 | 9 | 8784 | 1001 | 46676268 |
Tachycardia | 25.18 | 20.46 | 57 | 8736 | 99565 | 46577704 |
Bradypnoea | 25.09 | 20.46 | 12 | 8781 | 3027 | 46674242 |
Apnoea | 24.58 | 20.46 | 16 | 8777 | 7323 | 46669946 |
Euthyroid sick syndrome | 24.57 | 20.46 | 5 | 8788 | 67 | 46677202 |
Anaesthetic complication neurological | 24.46 | 20.46 | 6 | 8787 | 194 | 46677075 |
Ventricular fibrillation | 24.45 | 20.46 | 19 | 8774 | 11477 | 46665792 |
Arrhythmia | 23.73 | 20.46 | 31 | 8762 | 34810 | 46642459 |
Ureteral disorder | 22.83 | 20.46 | 6 | 8787 | 257 | 46677012 |
Bladder neck obstruction | 22.73 | 20.46 | 3 | 8790 | 0 | 46677269 |
Respiratory rate increased | 22.39 | 20.46 | 18 | 8775 | 11415 | 46665854 |
Platelet disorder | 22.08 | 20.46 | 9 | 8784 | 1554 | 46675715 |
Product dose omission issue | 21.71 | 20.46 | 3 | 8790 | 168517 | 46508752 |
Selective eating disorder | 21.12 | 20.46 | 9 | 8784 | 1736 | 46675533 |
Tidal volume decreased | 20.73 | 20.46 | 4 | 8789 | 40 | 46677229 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Anaphylactic shock | 282.76 | 20.41 | 113 | 7459 | 13880 | 29931026 |
Drug abuse | 242.31 | 20.41 | 185 | 7387 | 81887 | 29863019 |
Cystitis ulcerative | 131.12 | 20.41 | 18 | 7554 | 0 | 29944906 |
Hydronephrosis | 103.93 | 20.41 | 49 | 7523 | 8934 | 29935972 |
Cystitis | 82.72 | 20.41 | 41 | 7531 | 8333 | 29936573 |
Anaphylactic reaction | 82.05 | 20.41 | 63 | 7509 | 27919 | 29916987 |
Bronchospasm | 80.14 | 20.41 | 43 | 7529 | 10295 | 29934611 |
Biliary dilatation | 73.07 | 20.41 | 20 | 7552 | 742 | 29944164 |
Biopsy bladder abnormal | 72.84 | 20.41 | 10 | 7562 | 0 | 29944906 |
Cystitis interstitial | 71.54 | 20.41 | 11 | 7561 | 13 | 29944893 |
Hypotension | 70.77 | 20.41 | 156 | 7416 | 200409 | 29744497 |
Reduced bladder capacity | 70.22 | 20.41 | 10 | 7562 | 3 | 29944903 |
Drug screen positive | 69.96 | 20.41 | 30 | 7542 | 4377 | 29940529 |
Contracted bladder | 63.29 | 20.41 | 10 | 7562 | 16 | 29944890 |
Drug ineffective | 61.74 | 20.41 | 207 | 7365 | 340180 | 29604726 |
Delirium | 59.91 | 20.41 | 62 | 7510 | 40569 | 29904337 |
Hyperaesthesia | 58.96 | 20.41 | 25 | 7547 | 3548 | 29941358 |
Toxicity to various agents | 55.96 | 20.41 | 132 | 7440 | 177051 | 29767855 |
Bradycardia | 55.06 | 20.41 | 75 | 7497 | 65451 | 29879455 |
Respiratory depression | 55.05 | 20.41 | 35 | 7537 | 11468 | 29933438 |
Cholestasis | 51.81 | 20.41 | 46 | 7526 | 24904 | 29920002 |
Bladder disorder | 47.13 | 20.41 | 20 | 7552 | 2843 | 29942063 |
Tachycardia | 45.49 | 20.41 | 73 | 7499 | 73666 | 29871240 |
Laryngospasm | 42.18 | 20.41 | 15 | 7557 | 1328 | 29943578 |
Accidental death | 35.81 | 20.41 | 15 | 7557 | 2064 | 29942842 |
Status epilepticus | 34.78 | 20.41 | 26 | 7546 | 11046 | 29933860 |
Lower urinary tract symptoms | 34.65 | 20.41 | 8 | 7564 | 146 | 29944760 |
Diarrhoea | 34.50 | 20.41 | 21 | 7551 | 334082 | 29610824 |
Delayed recovery from anaesthesia | 34.44 | 20.41 | 11 | 7561 | 700 | 29944206 |
Cardiac arrest | 33.46 | 20.41 | 73 | 7499 | 92777 | 29852129 |
Serotonin syndrome | 33.24 | 20.41 | 31 | 7541 | 17860 | 29927046 |
Biliary tract disorder | 32.71 | 20.41 | 11 | 7561 | 824 | 29944082 |
Substance abuse | 32.63 | 20.41 | 21 | 7551 | 7019 | 29937887 |
Agitation | 31.24 | 20.41 | 52 | 7520 | 54021 | 29890885 |
Anaphylactoid shock | 31.11 | 20.41 | 9 | 7563 | 409 | 29944497 |
Hypoxia | 30.34 | 20.41 | 48 | 7524 | 47806 | 29897100 |
Apnoea | 29.83 | 20.41 | 19 | 7553 | 6239 | 29938667 |
Sedation | 29.71 | 20.41 | 28 | 7544 | 16345 | 29928561 |
Bladder hypertrophy | 29.54 | 20.41 | 8 | 7564 | 285 | 29944621 |
Hyperammonaemia | 29.44 | 20.41 | 18 | 7554 | 5502 | 29939404 |
Ureteral polyp | 29.13 | 20.41 | 4 | 7568 | 0 | 29944906 |
Sedation complication | 28.81 | 20.41 | 10 | 7562 | 824 | 29944082 |
Drug tolerance | 28.76 | 20.41 | 13 | 7559 | 2149 | 29942757 |
Drug dependence | 28.70 | 20.41 | 31 | 7541 | 21264 | 29923642 |
Wolff-Parkinson-White syndrome | 27.43 | 20.41 | 7 | 7565 | 197 | 29944709 |
Metabolic acidosis | 27.16 | 20.41 | 40 | 7532 | 37421 | 29907485 |
Cholangiolitis | 26.56 | 20.41 | 5 | 7567 | 31 | 29944875 |
Brain oedema | 26.00 | 20.41 | 23 | 7549 | 12375 | 29932531 |
Fatigue | 25.70 | 20.41 | 26 | 7546 | 320647 | 29624259 |
Haemodynamic instability | 25.57 | 20.41 | 19 | 7553 | 7996 | 29936910 |
Nystagmus | 25.35 | 20.41 | 15 | 7557 | 4323 | 29940583 |
Diabetes insipidus | 25.22 | 20.41 | 12 | 7560 | 2227 | 29942679 |
Pulseless electrical activity | 25.14 | 20.41 | 17 | 7555 | 6170 | 29938736 |
Ureteric stenosis | 25.02 | 20.41 | 10 | 7562 | 1221 | 29943685 |
Airway complication of anaesthesia | 25.01 | 20.41 | 6 | 7566 | 130 | 29944776 |
Diastolic hypertension | 24.72 | 20.41 | 5 | 7567 | 47 | 29944859 |
Propofol infusion syndrome | 24.67 | 20.41 | 9 | 7563 | 857 | 29944049 |
Dissociative disorder | 24.55 | 20.41 | 6 | 7566 | 141 | 29944765 |
Drug ineffective for unapproved indication | 24.46 | 20.41 | 21 | 7551 | 10859 | 29934047 |
Anaesthetic complication neurological | 23.99 | 20.41 | 7 | 7565 | 328 | 29944578 |
Haematuria traumatic | 23.71 | 20.41 | 6 | 7566 | 163 | 29944743 |
Pneumonia | 23.64 | 20.41 | 30 | 7542 | 334276 | 29610630 |
Transcranial electrical motor evoked potential monitoring abnormal | 23.59 | 20.41 | 4 | 7568 | 12 | 29944894 |
Urinary tract disorder | 23.33 | 20.41 | 11 | 7561 | 2000 | 29942906 |
Conversion disorder | 23.21 | 20.41 | 7 | 7565 | 368 | 29944538 |
Off label use | 23.20 | 20.41 | 124 | 7448 | 249166 | 29695740 |
Malaise | 22.71 | 20.41 | 7 | 7565 | 166955 | 29777951 |
Hepatocellular injury | 22.64 | 20.41 | 30 | 7542 | 25441 | 29919465 |
Neonatal hypoxia | 21.51 | 20.41 | 6 | 7566 | 239 | 29944667 |
Dyspnoea | 21.46 | 20.41 | 32 | 7540 | 333263 | 29611643 |
Circulatory collapse | 21.44 | 20.41 | 26 | 7546 | 20188 | 29924718 |
Behaviour disorder | 21.44 | 20.41 | 11 | 7561 | 2401 | 29942505 |
Hyperthermia malignant | 21.18 | 20.41 | 10 | 7562 | 1824 | 29943082 |
Drug interaction | 21.15 | 20.41 | 103 | 7469 | 199465 | 29745441 |
Source | Code | Description |
---|---|---|
ATC | N01AX03 | NERVOUS SYSTEM ANESTHETICS ANESTHETICS, GENERAL Other general anesthetics |
FDA EPC | N0000175681 | General Anesthetic |
CHEBI has role | CHEBI:35703 | xenobiotic |
CHEBI has role | CHEBI:38877 | intravenous anesthetics |
CHEBI has role | CHEBI:50910 | agente neurotoxico |
CHEBI has role | CHEBI:60643 | n-methyl-d-aspartate receptor antagonists |
CHEBI has role | CHEBI:78298 | environmental contaminants |
MeSH PA | D000700 | Analgesics |
MeSH PA | D000777 | Anesthetics |
MeSH PA | D000778 | Anesthetics, Dissociative |
MeSH PA | D018686 | Anesthetics, Intravenous |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D018691 | Excitatory Amino Acid Antagonists |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D018689 | Sensory System Agents |
FDA PE | N0000175975 | General Anesthesia |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
General anesthesia | indication | 50697003 | |
Local anesthesia | indication | 386761002 | |
Pain | off-label use | 22253000 | |
Inflammatory disease of mucous membrane | off-label use | 95361005 | |
Major depressive disorder | off-label use | 370143000 | |
Delirium | contraindication | 2776000 | |
Ocular hypertension | contraindication | 4210003 | DOID:9282 |
Alcoholism | contraindication | 7200002 | |
Myocardial infarction | contraindication | 22298006 | DOID:5844 |
Alcohol intoxication | contraindication | 25702006 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Decreased respiratory function | contraindication | 80954004 | |
Thyrotoxicosis | contraindication | 90739004 | DOID:7997 |
Acute disease of cardiovascular system | contraindication | 128487001 | |
Decompensated cardiac failure | contraindication | 195111005 | |
Cerebrovascular accident | contraindication | 230690007 | |
Raised intracranial pressure | contraindication | 271719001 | DOID:9428 |
Cerebral trauma | contraindication | 275382005 | |
Impaired cognition | contraindication | 386806002 | |
Myocardial ischemia | contraindication | 414795007 | DOID:3393 |
Hypertensive urgency | contraindication | 443482000 | |
Psychiatric Disturbance | contraindication | ||
Cardiac Decompensation | contraindication |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 7.65 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Glutamate [NMDA] receptor | Ion channel | BLOCKER | Ki | 6.38 | CHEMBL | CHEMBL | |||
Glutamate receptor ionotropic AMPA | Ion channel | OPENER | SCIENTIFIC LITERATURE | SCIENTIFIC LITERATURE | |||||
Glutamate NMDA receptor | Ion channel | IC50 | 6.21 | CHEMBL | |||||
Acetylcholine receptor subunit alpha | Ion channel | IC50 | 5.31 | CHEMBL |
ID | Source |
---|---|
4019796 | VUID |
N0000147885 | NUI |
D00711 | KEGG_DRUG |
1867-66-9 | SECONDARY_CAS_RN |
4018154 | VANDF |
4019796 | VANDF |
C0022614 | UMLSCUI |
CHEBI:6121 | CHEBI |
3821 | PUBCHEM_CID |
CHEMBL742 | ChEMBL_ID |
CHEMBL1714 | ChEMBL_ID |
D007649 | MESH_DESCRIPTOR_UI |
DB01221 | DRUGBANK_ID |
4233 | IUPHAR_LIGAND_ID |
2156 | INN_ID |
690G0D6V8H | UNII |
203184 | RXNORM |
4944 | MMSL |
9883 | MMSL |
d00272 | MMSL |
001403 | NDDF |
004581 | NDDF |
31706007 | SNOMEDCT_US |
333847008 | SNOMEDCT_US |
373464007 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9508 | INJECTION | 50 mg | INTRAMUSCULAR | ANDA | 27 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9509 | INJECTION | 100 mg | INTRAMUSCULAR | ANDA | 27 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-2051 | INJECTION, SOLUTION, CONCENTRATE | 100 mg | INTRAMUSCULAR | ANDA | 31 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-2053 | INJECTION, SOLUTION, CONCENTRATE | 50 mg | INTRAMUSCULAR | ANDA | 31 sections |
Ketalar | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-113 | INJECTION | 10 mg | INTRAMUSCULAR | NDA | 27 sections |
Ketalar | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-114 | INJECTION | 50 mg | INTRAMUSCULAR | NDA | 27 sections |
Ketalar | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-115 | INJECTION | 100 mg | INTRAMUSCULAR | NDA | 27 sections |
KETALAR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-037 | INJECTION | 10 mg | INTRAVENOUS | NDA | 14 sections |
KETAMINE HYDROCHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-038 | INJECTION, SOLUTION, CONCENTRATE | 50 mg | INTRAMUSCULAR | ANDA | 14 sections |
KETAMINE HYDROCHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-040 | INJECTION, SOLUTION, CONCENTRATE | 100 mg | INTRAMUSCULAR | ANDA | 14 sections |
KETAMINE HYDROCHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-108 | INJECTION, SOLUTION | 100 mg | INTRAVENOUS | ANDA | 14 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-4399 | INJECTION, SOLUTION, CONCENTRATE | 50 mg | INTRAMUSCULAR | ANDA | 19 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 67457-001 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 22 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 67457-108 | INJECTION, SOLUTION | 100 mg | INTRAVENOUS | ANDA | 22 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 67457-181 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 22 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 70518-2787 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 22 sections |
MKO Melt Dose Pack | HUMAN PRESCRIPTION DRUG LABEL | 3 | 71384-410 | TROCHE | 25 mg | SUBLINGUAL | unapproved drug other | 2 sections |
MKH Dose Pack | HUMAN PRESCRIPTION DRUG LABEL | 3 | 71384-420 | TROCHE | 25 mg | SUBLINGUAL | unapproved drug other | 2 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72572-320 | INJECTION | 50 mg | INTRAMUSCULAR | ANDA | 27 sections |
Ketamine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72572-321 | INJECTION | 100 mg | INTRAMUSCULAR | ANDA | 27 sections |