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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
ipriflavone 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
1477
35212-22-7
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
7-isopropoxyisoflavone
ipriflavone
iprivone
iprosten
osteofix
osten
Molecular weight: 280.32
Formula: C18H16O3
CLOGP: 3.92
LIPINSKI: 0
HAC: 3
HDO: 0
TPSA: 35.53
ALOGS: -4.80
ROTB: 3
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
M05BX01
MUSCULO-SKELETAL SYSTEM
DRUGS FOR TREATMENT OF BONE DISEASES
DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
Other drugs affecting bone structure and mineralization
CHEBI has role
CHEBI:50646
antiosteoporotic
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Postmenopausal osteoporosis
indication
102447009
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Prostaglandin G/H synthase 1
Enzyme
P23219
PGH1_HUMAN
IC50
5.53
DRUG MATRIX
Sodium-dependent noradrenaline transporter
Transporter
P23975
SC6A2_HUMAN
Ki
5.60
DRUG MATRIX
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External reference:
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entries
Search:
ID
Source
004192
NDDF
3521
INN_ID
3747
PUBCHEM_CID
4032065
VUID
4032065
VANDF
51487
RXNORM
80BJ7WN25Z
UNII
C0123903
UMLSCUI
C018986
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:31719
CHEBI
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Pharmaceutical products:
None
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Structure 🔎
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L1000
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ipriflavone