hexapropymate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
1367 358-52-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hexapropymate
  • hexopropynate
  • merinax
  • modirax
  • Molecular weight: 181.24
  • Formula: C10H15NO2
  • CLOGP: 1.90
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 52.32
  • ALOGS: -3.48
  • ROTB: 3

Drug dosage:

DoseUnitRoute
0.40 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,JAK2,MAP3K21,MAP3K7,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIM2,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK 35
kinase-selectivity-class AXL,GRK2 2
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05CM10 NERVOUS SYSTEM
PSYCHOLEPTICS
HYPNOTICS AND SEDATIVES
Other hypnotics and sedatives

Related Drugs by ATC class:

N05CM Other hypnotics and sedatives 13 drugs
apronalbromisovalcarbromalclomethiazoledexmedetomidineethchlorvynolmethaqualonemethylpentynolniaprazinepropiomazinescopolaminetriclofos show all 13 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07331 KEGG_DRUG
C0062664 UMLSCUI
CHEBI:134823 CHEBI
CHEMBL2104292 ChEMBL_ID
DB13662 DRUGBANK_ID
9661 PUBCHEM_CID
936 INN_ID
C001343 MESH_SUPPLEMENTAL_RECORD_UI
0J9RN2PRJ7 UNII

Pharmaceutical products:

None