clomethiazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
602 533-45-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chlormethiazole
  • clomethiazole
  • chlorethiazol
  • chlorethiazole
  • chlormethiazol
  • clomethiazolum
  • distraneurin
  • emineurina
  • chlormethiazole hydrochloride
  • chlormethiazole HCl
  • clomethiazole edisilate
A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate GAMMA-AMINOBUTYRIC ACID receptors response and it may also affect glycine receptors.
  • Molecular weight: 161.65
  • Formula: C6H8ClNS
  • CLOGP: 1.98
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA: 12.89
  • ALOGS: -2.38
  • ROTB: 2

Drug dosage:

DoseUnitRoute
1.50 g O
1.50 g P

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

clomethiazole