bendazac 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-inflammatory agents, ibufenac derivatives 303 20187-55-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bendazac lysine
  • bendazac
  • bendazolic acid
  • bindazac
  • Molecular weight: 282.30
  • Formula: C16H14N2O3
  • CLOGP: 3.13
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 64.35
  • ALOGS: -3.44
  • ROTB: 5

Drug dosage:

None

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 1 Bocci G, Oprea TI, Benet LZ
S (Water solubility) 86 mg/mL Bocci G, Oprea TI, Benet LZ

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M02AA11 MUSCULO-SKELETAL SYSTEM
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
Antiinflammatory preparations, non-steroids for topical use
ATC S01BC07 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS
Antiinflammatory agents, non-steroids
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents
MeSH PA D000963 Antimetabolites
MeSH PA D000960 Hypolipidemic Agents
MeSH PA D057847 Lipid Regulating Agents
CHEBI has role CHEBI:35475 non-steroidal anti-inflammatory agent
CHEBI has role CHEBI:48578 free radical scavengers

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.23 acidic
pKa2 1.44 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01594 KEGG_DRUG
81919-14-4 SECONDARY_CAS_RN
C0053097 UMLSCUI
CHEBI:31257 CHEBI
CHEMBL1089221 ChEMBL_ID
CHEMBL1089222 ChEMBL_ID
DB13501 DRUGBANK_ID
C000123 MESH_SUPPLEMENTAL_RECORD_UI
C036067 MESH_SUPPLEMENTAL_RECORD_UI
2313 PUBCHEM_CID
2654 INN_ID
G4AG71204O UNII
010873 NDDF
010892 NDDF

Pharmaceutical products:

None