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2022 Update-Veterinary Drugs & Uses
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
Exportin-1
Description:
Description
Accession: O14980
Swissprot: XPO1_HUMAN
Organism: Homo sapiens
Gene: XPO1
Target class: Nuclear other
Drug Relations:
selinexor
Selinexor reversibly inhibits nuclear export of tumor suppressor proteins (TSPs), growth regulators, and mRNAs of oncogenic proteins by blocking exportin 1(XPO1)
Bioactivity details
MOA