elcatonin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 994 | 60731-46-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
synthetic S-S bond between 1-7 amino acids displaced by C-C bond; deamino dicarba analog of eel calcitonin; has been given orphan drug approval for intrathecal treatment of intractable pain
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | H05BA04 | SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS CALCIUM HOMEOSTASIS ANTI-PARATHYROID AGENTS Calcitonin preparations |
| MeSH PA | D000077264 | Calcium-Regulating Hormones and Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.57 | acidic |
| pKa2 | 4.19 | acidic |
| pKa3 | 9.82 | acidic |
| pKa4 | 12.02 | acidic |
| pKa5 | 12.36 | acidic |
| pKa6 | 12.59 | acidic |
| pKa7 | 12.74 | acidic |
| pKa8 | 12.81 | acidic |
| pKa9 | 13.12 | acidic |
| pKa10 | 13.18 | acidic |
| pKa11 | 13.32 | acidic |
| pKa12 | 13.4 | acidic |
| pKa13 | 13.47 | acidic |
| pKa14 | 13.51 | acidic |
| pKa15 | 13.62 | acidic |
| pKa16 | 13.75 | acidic |
| pKa17 | 13.81 | acidic |
| pKa18 | 13.85 | acidic |
| pKa19 | 13.87 | acidic |
| pKa20 | 11.25 | Basic |
| pKa21 | 10.81 | Basic |
| pKa22 | 10.31 | Basic |
| pKa23 | 6.69 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D03287 | KEGG_DRUG |
| C0115656 | UMLSCUI |
| CHEBI:135916 | CHEBI |
| CHEMBL2104402 | ChEMBL_ID |
| CHEMBL507951 | ChEMBL_ID |
| DB13742 | DRUGBANK_ID |
| C012755 | MESH_SUPPLEMENTAL_RECORD_UI |
| 4946 | INN_ID |
| W0CMS474JK | UNII |
| 702803000 | SNOMEDCT_US |
| 164512660 | PUBCHEM_CID |
Pharmaceutical products:
None