Stem definition | Drug id | CAS RN |
---|---|---|
antineoplastics, daunorubicin derivatives | 960 | 23214-92-8 |
None
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 10 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 3.50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 4.47 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 5 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 22 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 15 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.28 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 32 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Aug. 7, 1974 | FDA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Febrile neutropenia | 4780.46 | 12.98 | 2671 | 89369 | 94996 | 50418088 |
Neutropenia | 2549.90 | 12.98 | 2123 | 89917 | 145842 | 50367242 |
Acute myeloid leukaemia | 1089.33 | 12.98 | 537 | 91503 | 14537 | 50498547 |
Cardiotoxicity | 915.78 | 12.98 | 378 | 91662 | 6649 | 50506435 |
Mucosal inflammation | 912.44 | 12.98 | 680 | 91360 | 39462 | 50473622 |
Disease progression | 843.33 | 12.98 | 953 | 91087 | 94913 | 50418171 |
Myelodysplastic syndrome | 802.49 | 12.98 | 438 | 91602 | 14694 | 50498390 |
Thrombocytopenia | 796.15 | 12.98 | 1067 | 90973 | 126606 | 50386478 |
Second primary malignancy | 781.04 | 12.98 | 336 | 91704 | 6578 | 50506506 |
Haematotoxicity | 776.32 | 12.98 | 348 | 91692 | 7547 | 50505537 |
Palmar-plantar erythrodysaesthesia syndrome | 707.15 | 12.98 | 446 | 91594 | 19652 | 50493432 |
Malignant neoplasm progression | 662.29 | 12.98 | 714 | 91326 | 67410 | 50445674 |
Product use in unapproved indication | 640.77 | 12.98 | 914 | 91126 | 114905 | 50398179 |
Bone marrow failure | 565.83 | 12.98 | 440 | 91600 | 27184 | 50485900 |
Pancytopenia | 547.41 | 12.98 | 718 | 91322 | 83312 | 50429772 |
Cardiomyopathy | 496.59 | 12.98 | 325 | 91715 | 15261 | 50497823 |
Diffuse large B-cell lymphoma recurrent | 492.69 | 12.98 | 162 | 91878 | 1433 | 50511651 |
Ejection fraction decreased | 491.86 | 12.98 | 345 | 91695 | 18175 | 50494909 |
Febrile bone marrow aplasia | 468.19 | 12.98 | 229 | 91811 | 6082 | 50507002 |
Off label use | 465.34 | 12.98 | 1896 | 90144 | 472530 | 50040554 |
Neoplasm progression | 439.81 | 12.98 | 389 | 91651 | 28768 | 50484316 |
Anaemia | 402.45 | 12.98 | 1187 | 90853 | 251269 | 50261815 |
Pneumocystis jirovecii pneumonia | 368.18 | 12.98 | 264 | 91776 | 14399 | 50498685 |
Joint swelling | 368.15 | 12.98 | 19 | 92021 | 245267 | 50267817 |
Metastases to bone | 351.94 | 12.98 | 279 | 91761 | 17716 | 50495368 |
Rheumatoid arthritis | 342.62 | 12.98 | 5 | 92035 | 202545 | 50310539 |
Ovarian failure | 323.78 | 12.98 | 108 | 91932 | 1003 | 50512081 |
Neuropathy peripheral | 312.90 | 12.98 | 600 | 91440 | 96157 | 50416927 |
Leukopenia | 303.27 | 12.98 | 484 | 91556 | 67044 | 50446040 |
Left ventricular dysfunction | 303.12 | 12.98 | 206 | 91834 | 10300 | 50502784 |
Cardiac failure | 302.48 | 12.98 | 516 | 91524 | 75524 | 50437560 |
Tumour lysis syndrome | 299.93 | 12.98 | 180 | 91860 | 7241 | 50505843 |
Pain | 277.98 | 12.98 | 390 | 91650 | 578513 | 49934571 |
Fall | 276.55 | 12.98 | 132 | 91908 | 334800 | 50178284 |
Septic shock | 273.64 | 12.98 | 422 | 91618 | 56753 | 50456331 |
Abdominal discomfort | 265.49 | 12.98 | 50 | 91990 | 231591 | 50281493 |
Pyrexia | 261.38 | 12.98 | 1371 | 90669 | 378832 | 50134252 |
Neutrophil count decreased | 261.05 | 12.98 | 368 | 91672 | 45658 | 50467426 |
Metastases to lung | 250.81 | 12.98 | 187 | 91853 | 10833 | 50502251 |
Myelosuppression | 243.99 | 12.98 | 200 | 91840 | 13317 | 50499767 |
Metastases to liver | 240.86 | 12.98 | 236 | 91804 | 19868 | 50493216 |
Contraindicated product administered | 238.71 | 12.98 | 7 | 92033 | 148951 | 50364133 |
Systemic lupus erythematosus | 235.48 | 12.98 | 4 | 92036 | 140618 | 50372466 |
Bone pain | 235.02 | 12.98 | 355 | 91685 | 46874 | 50466210 |
Sepsis | 234.54 | 12.98 | 649 | 91391 | 132276 | 50380808 |
Neutropenic sepsis | 233.97 | 12.98 | 199 | 91841 | 13948 | 50499136 |
Completed suicide | 224.04 | 12.98 | 3 | 92037 | 131886 | 50381198 |
Headache | 221.90 | 12.98 | 363 | 91677 | 506172 | 50006912 |
Hepatitis B reactivation | 221.20 | 12.98 | 97 | 91943 | 1990 | 50511094 |
Diffuse large B-cell lymphoma refractory | 221.05 | 12.98 | 80 | 91960 | 966 | 50512118 |
Congestive cardiomyopathy | 220.81 | 12.98 | 133 | 91907 | 5385 | 50507699 |
Weight increased | 214.10 | 12.98 | 52 | 91988 | 201839 | 50311245 |
Product dose omission issue | 212.04 | 12.98 | 39 | 92001 | 183799 | 50329285 |
Peripheral swelling | 210.79 | 12.98 | 57 | 91983 | 205879 | 50307205 |
Arthropathy | 201.54 | 12.98 | 25 | 92015 | 157881 | 50355203 |
Drug hypersensitivity | 199.37 | 12.98 | 104 | 91936 | 250906 | 50262178 |
Staphylococcal bacteraemia | 198.91 | 12.98 | 119 | 91921 | 4758 | 50508326 |
Arthralgia | 198.04 | 12.98 | 308 | 91732 | 438394 | 50074690 |
Swelling | 197.46 | 12.98 | 60 | 91980 | 200812 | 50312272 |
Nasopharyngitis | 194.45 | 12.98 | 55 | 91985 | 192872 | 50320212 |
Synovitis | 194.24 | 12.98 | 7 | 92033 | 123858 | 50389226 |
Acute promyelocytic leukaemia | 192.02 | 12.98 | 69 | 91971 | 815 | 50512269 |
Neutropenic colitis | 186.16 | 12.98 | 90 | 91950 | 2327 | 50510757 |
Pruritus | 182.47 | 12.98 | 149 | 91891 | 283419 | 50229665 |
Musculoskeletal stiffness | 180.53 | 12.98 | 14 | 92026 | 128467 | 50384617 |
Disease recurrence | 178.45 | 12.98 | 201 | 91839 | 19880 | 50493204 |
Posterior reversible encephalopathy syndrome | 178.36 | 12.98 | 175 | 91865 | 14753 | 50498331 |
Therapeutic product effect decreased | 172.48 | 12.98 | 22 | 92018 | 136028 | 50377056 |
Cytopenia | 169.29 | 12.98 | 135 | 91905 | 8640 | 50504444 |
Therapy partial responder | 168.49 | 12.98 | 120 | 91920 | 6471 | 50506613 |
Sinusitis | 162.16 | 12.98 | 54 | 91986 | 170504 | 50342580 |
Ascites | 156.73 | 12.98 | 254 | 91786 | 35607 | 50477477 |
Hepatitis B | 155.62 | 12.98 | 90 | 91950 | 3376 | 50509708 |
Metastases to lymph nodes | 154.95 | 12.98 | 117 | 91923 | 6907 | 50506177 |
Neurotoxicity | 154.53 | 12.98 | 161 | 91879 | 14579 | 50498505 |
Wound | 144.56 | 12.98 | 13 | 92027 | 105781 | 50407303 |
Dizziness | 144.21 | 12.98 | 256 | 91784 | 346113 | 50166971 |
Rash | 144.13 | 12.98 | 369 | 91671 | 437102 | 50075982 |
Anti-Muellerian hormone level decreased | 142.71 | 12.98 | 34 | 92006 | 70 | 50513014 |
Pleural effusion | 141.83 | 12.98 | 396 | 91644 | 81058 | 50432026 |
Injection site pain | 135.87 | 12.98 | 20 | 92020 | 111004 | 50402080 |
Drug intolerance | 134.90 | 12.98 | 120 | 91920 | 218984 | 50294100 |
Peripheral sensory neuropathy | 134.89 | 12.98 | 105 | 91935 | 6486 | 50506598 |
Interstitial lung disease | 133.16 | 12.98 | 297 | 91743 | 52879 | 50460205 |
Post transplant lymphoproliferative disorder | 129.81 | 12.98 | 86 | 91954 | 4118 | 50508966 |
Insomnia | 127.94 | 12.98 | 80 | 91960 | 174785 | 50338299 |
Stomatitis | 125.78 | 12.98 | 438 | 91602 | 100906 | 50412178 |
Pneumonitis | 124.86 | 12.98 | 206 | 91834 | 29304 | 50483780 |
Drug ineffective | 122.97 | 12.98 | 931 | 91109 | 818402 | 49694682 |
Aplasia | 122.60 | 12.98 | 80 | 91960 | 3733 | 50509351 |
Multiple organ dysfunction syndrome | 118.10 | 12.98 | 274 | 91766 | 50063 | 50463021 |
Contusion | 116.69 | 12.98 | 30 | 92010 | 112153 | 50400931 |
Discomfort | 114.63 | 12.98 | 28 | 92012 | 108352 | 50404732 |
Progressive multifocal leukoencephalopathy | 114.50 | 12.98 | 122 | 91918 | 11335 | 50501749 |
Platelet count decreased | 114.48 | 12.98 | 423 | 91617 | 100303 | 50412781 |
B-cell lymphoma recurrent | 112.77 | 12.98 | 38 | 92002 | 365 | 50512719 |
Somnolence | 109.15 | 12.98 | 74 | 91966 | 154911 | 50358173 |
Urticaria | 108.32 | 12.98 | 50 | 91990 | 129511 | 50383573 |
Muscle spasms | 107.24 | 12.98 | 47 | 91993 | 125506 | 50387578 |
Feeling abnormal | 107.15 | 12.98 | 47 | 91993 | 125445 | 50387639 |
Acute lymphocytic leukaemia recurrent | 106.95 | 12.98 | 58 | 91982 | 1917 | 50511167 |
Lymphadenopathy | 105.99 | 12.98 | 206 | 91834 | 33293 | 50479791 |
Polyneuropathy | 103.65 | 12.98 | 119 | 91921 | 12012 | 50501072 |
Breast cancer recurrent | 103.53 | 12.98 | 72 | 91968 | 3736 | 50509348 |
White blood cell count decreased | 102.95 | 12.98 | 453 | 91587 | 116269 | 50396815 |
Pain in extremity | 101.87 | 12.98 | 215 | 91825 | 272650 | 50240434 |
Overdose | 101.20 | 12.98 | 28 | 92012 | 99699 | 50413385 |
Breast cancer metastatic | 101.17 | 12.98 | 109 | 91931 | 10255 | 50502829 |
Metastases to central nervous system | 100.35 | 12.98 | 113 | 91927 | 11169 | 50501915 |
Hepatic enzyme increased | 100.26 | 12.98 | 63 | 91977 | 137317 | 50375767 |
Arthritis | 98.62 | 12.98 | 19 | 92021 | 86702 | 50426382 |
Anxiety | 98.06 | 12.98 | 107 | 91933 | 177499 | 50335585 |
Haemophagocytic lymphohistiocytosis | 97.20 | 12.98 | 98 | 91942 | 8535 | 50504549 |
Small intestinal obstruction | 96.31 | 12.98 | 132 | 91908 | 15936 | 50497148 |
Skin toxicity | 94.88 | 12.98 | 69 | 91971 | 3844 | 50509240 |
Premature menopause | 94.50 | 12.98 | 40 | 92000 | 750 | 50512334 |
Premature delivery | 91.90 | 12.98 | 159 | 91881 | 23504 | 50489580 |
Blood pressure increased | 91.83 | 12.98 | 65 | 91975 | 133067 | 50380017 |
Pericarditis | 87.88 | 12.98 | 18 | 92022 | 78671 | 50434413 |
Injection site erythema | 83.98 | 12.98 | 17 | 92023 | 74919 | 50438165 |
Hospitalisation | 83.65 | 12.98 | 12 | 92028 | 67925 | 50445159 |
Epstein-Barr virus infection | 83.52 | 12.98 | 82 | 91958 | 6915 | 50506169 |
Drug resistance | 82.27 | 12.98 | 134 | 91906 | 18855 | 50494229 |
Neoplasm recurrence | 81.83 | 12.98 | 52 | 91988 | 2317 | 50510767 |
Confusional state | 81.28 | 12.98 | 133 | 91907 | 185795 | 50327289 |
Bacteraemia | 81.18 | 12.98 | 115 | 91925 | 14318 | 50498766 |
Malaise | 80.94 | 12.98 | 325 | 91715 | 335207 | 50177877 |
Asthma | 80.23 | 12.98 | 31 | 92009 | 89306 | 50423778 |
Smooth muscle cell neoplasm | 79.01 | 12.98 | 35 | 92005 | 736 | 50512348 |
Respiratory failure | 78.95 | 12.98 | 352 | 91688 | 90829 | 50422255 |
Metastases to peritoneum | 78.04 | 12.98 | 54 | 91986 | 2779 | 50510305 |
Gene mutation | 76.36 | 12.98 | 40 | 92000 | 1231 | 50511853 |
Gait disturbance | 75.69 | 12.98 | 97 | 91943 | 149908 | 50363176 |
Depression | 75.46 | 12.98 | 115 | 91925 | 165308 | 50347776 |
Metastasis | 75.32 | 12.98 | 63 | 91977 | 4312 | 50508772 |
Irritable bowel syndrome | 73.96 | 12.98 | 5 | 92035 | 51436 | 50461648 |
Ileus | 73.80 | 12.98 | 105 | 91935 | 13124 | 50499960 |
Neutrophil count abnormal | 72.78 | 12.98 | 49 | 91991 | 2410 | 50510674 |
Condition aggravated | 72.71 | 12.98 | 286 | 91754 | 296772 | 50216312 |
Metastases to breast | 72.59 | 12.98 | 25 | 92015 | 258 | 50512826 |
Systemic candida | 69.48 | 12.98 | 50 | 91990 | 2740 | 50510344 |
Myeloid leukaemia | 68.99 | 12.98 | 25 | 92015 | 303 | 50512781 |
Bone marrow disorder | 67.89 | 12.98 | 43 | 91997 | 1905 | 50511179 |
Bronchitis | 67.77 | 12.98 | 54 | 91986 | 104105 | 50408979 |
Computerised tomogram thorax abnormal | 67.70 | 12.98 | 38 | 92002 | 1345 | 50511739 |
Lymphopenia | 67.35 | 12.98 | 110 | 91930 | 15511 | 50497573 |
Acute lymphocytic leukaemia | 67.16 | 12.98 | 45 | 91995 | 2196 | 50510888 |
Refractory anaemia with an excess of blasts | 67.15 | 12.98 | 26 | 92014 | 383 | 50512701 |
Abdominal pain upper | 66.81 | 12.98 | 117 | 91923 | 159192 | 50353892 |
Osteoarthritis | 66.42 | 12.98 | 21 | 92019 | 68585 | 50444499 |
Fibromyalgia | 65.77 | 12.98 | 4 | 92036 | 44974 | 50468110 |
Blood cholesterol increased | 65.14 | 12.98 | 11 | 92029 | 55204 | 50457880 |
Pneumatosis intestinalis | 64.88 | 12.98 | 43 | 91997 | 2060 | 50511024 |
Acquired gene mutation | 64.17 | 12.98 | 31 | 92009 | 800 | 50512284 |
Pericardial effusion | 64.11 | 12.98 | 143 | 91897 | 25446 | 50487638 |
Gastrointestinal toxicity | 63.79 | 12.98 | 59 | 91981 | 4618 | 50508466 |
Bronchopulmonary aspergillosis | 62.39 | 12.98 | 73 | 91967 | 7519 | 50505565 |
Drug abuse | 62.22 | 12.98 | 16 | 92024 | 59830 | 50453254 |
Loss of personal independence in daily activities | 61.75 | 12.98 | 25 | 92015 | 70025 | 50443059 |
Leukaemia | 61.52 | 12.98 | 51 | 91989 | 3448 | 50509636 |
Cataract | 61.50 | 12.98 | 7 | 92033 | 47293 | 50465791 |
Hypogammaglobulinaemia | 61.08 | 12.98 | 63 | 91977 | 5636 | 50507448 |
Injection site swelling | 60.23 | 12.98 | 4 | 92036 | 41769 | 50471315 |
Wheezing | 60.05 | 12.98 | 19 | 92021 | 62028 | 50451056 |
Ventricular hypokinesia | 59.77 | 12.98 | 53 | 91987 | 3927 | 50509157 |
Agranulocytosis | 58.56 | 12.98 | 124 | 91916 | 21297 | 50491787 |
Impaired healing | 58.19 | 12.98 | 27 | 92013 | 69759 | 50443325 |
Injection site pruritus | 57.88 | 12.98 | 4 | 92036 | 40407 | 50472677 |
Metastases to skin | 57.06 | 12.98 | 34 | 92006 | 1349 | 50511735 |
Cystitis haemorrhagic | 56.99 | 12.98 | 50 | 91990 | 3652 | 50509432 |
Pulmonary toxicity | 56.94 | 12.98 | 60 | 91980 | 5502 | 50507582 |
Lower respiratory tract infection | 56.31 | 12.98 | 54 | 91986 | 95147 | 50417937 |
Helicobacter infection | 56.26 | 12.98 | 11 | 92029 | 49691 | 50463393 |
Varicella zoster virus infection | 56.10 | 12.98 | 42 | 91998 | 2447 | 50510637 |
Encephalopathy | 55.80 | 12.98 | 161 | 91879 | 33550 | 50479534 |
Lymphadenitis | 55.79 | 12.98 | 43 | 91997 | 2617 | 50510467 |
Salivary gland cancer | 55.26 | 12.98 | 18 | 92022 | 154 | 50512930 |
Stress | 54.75 | 12.98 | 15 | 92025 | 53778 | 50459306 |
Capillary leak syndrome | 54.36 | 12.98 | 37 | 92003 | 1853 | 50511231 |
Nephropathy toxic | 54.33 | 12.98 | 70 | 91970 | 7959 | 50505125 |
Venoocclusive disease | 54.26 | 12.98 | 37 | 92003 | 1859 | 50511225 |
Embolism | 53.96 | 12.98 | 65 | 91975 | 6903 | 50506181 |
Intestinal perforation | 53.84 | 12.98 | 80 | 91960 | 10399 | 50502685 |
Peripheral motor neuropathy | 53.43 | 12.98 | 33 | 92007 | 1398 | 50511686 |
Balance disorder | 53.39 | 12.98 | 31 | 92009 | 70559 | 50442525 |
Injection site reaction | 52.73 | 12.98 | 13 | 92027 | 50019 | 50463065 |
White blood cell count abnormal | 52.72 | 12.98 | 57 | 91983 | 5383 | 50507701 |
Pneumocystis jirovecii infection | 51.70 | 12.98 | 31 | 92009 | 1244 | 50511840 |
Injection site bruising | 51.63 | 12.98 | 4 | 92036 | 36764 | 50476320 |
Drug interaction | 51.50 | 12.98 | 188 | 91852 | 199433 | 50313651 |
Venoocclusive liver disease | 50.98 | 12.98 | 50 | 91990 | 4211 | 50508873 |
Inappropriate schedule of product administration | 50.93 | 12.98 | 34 | 92006 | 71797 | 50441287 |
Atelectasis | 50.22 | 12.98 | 106 | 91934 | 18164 | 50494920 |
Alopecia | 50.21 | 12.98 | 252 | 91788 | 244795 | 50268289 |
Extravasation | 50.13 | 12.98 | 36 | 92004 | 1966 | 50511118 |
Cerebrovascular accident | 50.08 | 12.98 | 59 | 91981 | 94621 | 50418463 |
Suicide attempt | 49.78 | 12.98 | 16 | 92024 | 51716 | 50461368 |
Memory impairment | 49.32 | 12.98 | 43 | 91997 | 79317 | 50433767 |
Diffuse large B-cell lymphoma | 49.14 | 12.98 | 56 | 91984 | 5606 | 50507478 |
Injury | 49.12 | 12.98 | 14 | 92026 | 48911 | 50464173 |
Mobility decreased | 48.87 | 12.98 | 44 | 91996 | 79904 | 50433180 |
Cardiomyopathy acute | 48.64 | 12.98 | 17 | 92023 | 184 | 50512900 |
JC virus infection | 48.60 | 12.98 | 34 | 92006 | 1781 | 50511303 |
Heart rate decreased | 48.47 | 12.98 | 5 | 92035 | 36492 | 50476592 |
Metastases to pleura | 48.46 | 12.98 | 30 | 92010 | 1276 | 50511808 |
Thrombotic microangiopathy | 47.90 | 12.98 | 69 | 91971 | 8722 | 50504362 |
Tremor | 47.60 | 12.98 | 85 | 91955 | 114818 | 50398266 |
5q minus syndrome | 47.44 | 12.98 | 17 | 92023 | 199 | 50512885 |
Recurrent cancer | 47.25 | 12.98 | 33 | 92007 | 1724 | 50511360 |
Acute hepatitis B | 46.97 | 12.98 | 19 | 92021 | 316 | 50512768 |
Perineal infection | 46.72 | 12.98 | 15 | 92025 | 122 | 50512962 |
Klebsiella infection | 46.00 | 12.98 | 61 | 91979 | 7133 | 50505951 |
Folliculitis | 45.86 | 12.98 | 8 | 92032 | 39217 | 50473867 |
Neutropenic infection | 45.57 | 12.98 | 27 | 92013 | 1060 | 50512024 |
Nephrolithiasis | 45.44 | 12.98 | 5 | 92035 | 34688 | 50478396 |
Cardiac failure acute | 45.31 | 12.98 | 65 | 91975 | 8185 | 50504899 |
Suicidal ideation | 45.30 | 12.98 | 22 | 92018 | 55363 | 50457721 |
Lymphoma transformation | 45.09 | 12.98 | 15 | 92025 | 138 | 50512946 |
Pulmonary embolism | 44.96 | 12.98 | 328 | 91712 | 101376 | 50411708 |
Philadelphia chromosome positive | 44.70 | 12.98 | 19 | 92021 | 360 | 50512724 |
Fatigue | 44.70 | 12.98 | 965 | 91075 | 706636 | 49806448 |
Blood glucose increased | 43.90 | 12.98 | 39 | 92001 | 71285 | 50441799 |
Nasal congestion | 43.84 | 12.98 | 19 | 92021 | 51101 | 50461983 |
Perineal necrosis | 43.69 | 12.98 | 14 | 92026 | 113 | 50512971 |
Hypersensitivity | 43.64 | 12.98 | 222 | 91818 | 214939 | 50298145 |
Cutaneous calcification | 42.94 | 12.98 | 13 | 92027 | 85 | 50512999 |
Palpitations | 42.77 | 12.98 | 66 | 91974 | 94440 | 50418644 |
Ovarian cancer recurrent | 42.54 | 12.98 | 24 | 92016 | 858 | 50512226 |
Plasmacytoma | 42.42 | 12.98 | 35 | 92005 | 2350 | 50510734 |
Respiratory syncytial virus infection | 41.83 | 12.98 | 49 | 91991 | 5053 | 50508031 |
Alveolar soft part sarcoma | 41.82 | 12.98 | 13 | 92027 | 94 | 50512990 |
Clonal evolution | 41.25 | 12.98 | 12 | 92028 | 67 | 50513017 |
Metastases to spine | 41.12 | 12.98 | 37 | 92003 | 2794 | 50510290 |
Myasthenia gravis crisis | 41.01 | 12.98 | 18 | 92022 | 370 | 50512714 |
Gastrosplenic fistula | 40.80 | 12.98 | 11 | 92029 | 44 | 50513040 |
Joint stiffness | 40.65 | 12.98 | 4 | 92036 | 30304 | 50482780 |
Alveolitis | 40.57 | 12.98 | 35 | 92005 | 2499 | 50510585 |
Gastrointestinal fungal infection | 40.35 | 12.98 | 16 | 92024 | 252 | 50512832 |
Fluid retention | 40.10 | 12.98 | 21 | 92019 | 50628 | 50462456 |
Central nervous system lymphoma | 39.92 | 12.98 | 27 | 92013 | 1338 | 50511746 |
Pseudomonal sepsis | 39.75 | 12.98 | 32 | 92008 | 2075 | 50511009 |
Enterococcal bacteraemia | 39.48 | 12.98 | 26 | 92014 | 1232 | 50511852 |
Organising pneumonia | 39.39 | 12.98 | 46 | 91994 | 4728 | 50508356 |
Treatment failure | 39.31 | 12.98 | 124 | 91916 | 137513 | 50375571 |
Amnesia | 39.04 | 12.98 | 14 | 92026 | 42246 | 50470838 |
Heart rate abnormal | 38.99 | 12.98 | 42 | 91998 | 3950 | 50509134 |
Blood lactate dehydrogenase increased | 38.94 | 12.98 | 100 | 91940 | 19462 | 50493622 |
Premature baby | 38.87 | 12.98 | 96 | 91944 | 18241 | 50494843 |
Hypoxia | 38.81 | 12.98 | 190 | 91850 | 50933 | 50462151 |
Migraine | 38.65 | 12.98 | 48 | 91992 | 75232 | 50437852 |
Ileus paralytic | 38.49 | 12.98 | 42 | 91998 | 4008 | 50509076 |
Secondary immunodeficiency | 38.37 | 12.98 | 25 | 92015 | 1163 | 50511921 |
Squamous cell carcinoma of the oral cavity | 38.35 | 12.98 | 16 | 92024 | 289 | 50512795 |
Myelopathy | 38.25 | 12.98 | 34 | 92006 | 2527 | 50510557 |
Device related infection | 38.22 | 12.98 | 103 | 91937 | 20632 | 50492452 |
Clostridium bacteraemia | 38.10 | 12.98 | 14 | 92026 | 177 | 50512907 |
Adverse drug reaction | 38.00 | 12.98 | 27 | 92013 | 55195 | 50457889 |
Primary cardiac lymphoma | 37.95 | 12.98 | 9 | 92031 | 18 | 50513066 |
Gastrooesophageal reflux disease | 37.93 | 12.98 | 50 | 91990 | 76378 | 50436706 |
Neck pain | 37.85 | 12.98 | 29 | 92011 | 57038 | 50456046 |
Intertrigo | 37.80 | 12.98 | 17 | 92023 | 371 | 50512713 |
Cardiogenic shock | 37.76 | 12.98 | 86 | 91954 | 15513 | 50497571 |
Colony stimulating factor therapy | 37.70 | 12.98 | 16 | 92024 | 302 | 50512782 |
Mucosal toxicity | 37.51 | 12.98 | 16 | 92024 | 306 | 50512778 |
Chemotherapy | 37.49 | 12.98 | 26 | 92014 | 1343 | 50511741 |
Hypoglycaemia | 37.13 | 12.98 | 26 | 92014 | 53555 | 50459529 |
Premature labour | 36.81 | 12.98 | 71 | 91969 | 11405 | 50501679 |
Bone lesion | 36.44 | 12.98 | 46 | 91994 | 5124 | 50507960 |
T-cell type acute leukaemia | 36.15 | 12.98 | 10 | 92030 | 45 | 50513039 |
Invasive ductal breast carcinoma | 36.02 | 12.98 | 49 | 91991 | 5872 | 50507212 |
Myocardial infarction | 35.85 | 12.98 | 67 | 91973 | 88960 | 50424124 |
Humoral immune defect | 35.82 | 12.98 | 11 | 92029 | 76 | 50513008 |
Hypertriglyceridaemia | 35.79 | 12.98 | 47 | 91993 | 5444 | 50507640 |
Mantle cell lymphoma recurrent | 35.73 | 12.98 | 12 | 92028 | 114 | 50512970 |
Cardiac failure chronic | 35.70 | 12.98 | 38 | 92002 | 3525 | 50509559 |
Visual impairment | 35.61 | 12.98 | 43 | 91997 | 68232 | 50444852 |
Amniotic fluid index decreased | 35.59 | 12.98 | 8 | 92032 | 11 | 50513073 |
Incorrect dose administered | 35.57 | 12.98 | 22 | 92018 | 48392 | 50464692 |
Acute myelomonocytic leukaemia | 35.33 | 12.98 | 13 | 92027 | 165 | 50512919 |
Hepatitis E | 35.21 | 12.98 | 24 | 92016 | 1205 | 50511879 |
Ovarian epithelial cancer recurrent | 35.18 | 12.98 | 8 | 92032 | 12 | 50513072 |
Flagellate dermatitis | 35.12 | 12.98 | 13 | 92027 | 168 | 50512916 |
Mesenteric abscess | 35.09 | 12.98 | 11 | 92029 | 82 | 50513002 |
Lung infiltration | 34.85 | 12.98 | 76 | 91964 | 13317 | 50499767 |
Toxic cardiomyopathy | 34.83 | 12.98 | 12 | 92028 | 124 | 50512960 |
Blast cells present | 34.80 | 12.98 | 16 | 92024 | 368 | 50512716 |
Unintentional medical device removal | 34.62 | 12.98 | 46 | 91994 | 5389 | 50507695 |
Enterococcal sepsis | 34.41 | 12.98 | 24 | 92016 | 1251 | 50511833 |
Escherichia bacteraemia | 34.39 | 12.98 | 35 | 92005 | 3081 | 50510003 |
Plasma cell leukaemia | 34.36 | 12.98 | 22 | 92018 | 993 | 50512091 |
Osteomyelitis bacterial | 34.05 | 12.98 | 13 | 92027 | 184 | 50512900 |
Haemoglobin abnormal | 33.90 | 12.98 | 41 | 91999 | 4371 | 50508713 |
Body dysmorphic disorder | 33.65 | 12.98 | 14 | 92026 | 251 | 50512833 |
Ill-defined disorder | 33.49 | 12.98 | 30 | 92010 | 54624 | 50458460 |
Loss of consciousness | 33.45 | 12.98 | 89 | 91951 | 104264 | 50408820 |
Limb discomfort | 33.23 | 12.98 | 3 | 92037 | 24354 | 50488730 |
Musculoskeletal pain | 33.05 | 12.98 | 50 | 91990 | 72127 | 50440957 |
Necrotising gastritis | 32.95 | 12.98 | 10 | 92030 | 66 | 50513018 |
Hydrothorax | 32.86 | 12.98 | 19 | 92021 | 712 | 50512372 |
Large intestinal ulcer perforation | 32.82 | 12.98 | 10 | 92030 | 67 | 50513017 |
Metastases to meninges | 32.76 | 12.98 | 28 | 92012 | 1974 | 50511110 |
Rhabdomyolysis | 32.68 | 12.98 | 15 | 92025 | 39012 | 50474072 |
Localised infection | 32.56 | 12.98 | 4 | 92036 | 25481 | 50487603 |
Exposure during pregnancy | 32.54 | 12.98 | 350 | 91690 | 120665 | 50392419 |
Infection reactivation | 32.45 | 12.98 | 21 | 92019 | 966 | 50512118 |
Mitral valve incompetence | 32.42 | 12.98 | 87 | 91953 | 17384 | 50495700 |
Unevaluable event | 32.39 | 12.98 | 22 | 92018 | 46044 | 50467040 |
Pyomyositis | 32.20 | 12.98 | 15 | 92025 | 356 | 50512728 |
Hepatic failure | 32.07 | 12.98 | 130 | 91910 | 32153 | 50480931 |
Colitis | 32.01 | 12.98 | 147 | 91893 | 38382 | 50474702 |
Therapeutic response delayed | 31.84 | 12.98 | 17 | 92023 | 544 | 50512540 |
Traumatic lung injury | 31.77 | 12.98 | 24 | 92016 | 1417 | 50511667 |
Epstein-Barr virus associated lymphoma | 31.76 | 12.98 | 16 | 92024 | 453 | 50512631 |
Leukoerythroblastosis | 31.66 | 12.98 | 13 | 92027 | 225 | 50512859 |
Amenorrhoea | 31.62 | 12.98 | 56 | 91984 | 8428 | 50504656 |
Bicytopenia | 31.52 | 12.98 | 27 | 92013 | 1909 | 50511175 |
Pneumonia fungal | 31.35 | 12.98 | 39 | 92001 | 4281 | 50508803 |
Respiratory arrest | 31.23 | 12.98 | 8 | 92032 | 30001 | 50483083 |
Heart rate increased | 31.22 | 12.98 | 58 | 91982 | 77192 | 50435892 |
Blood pressure fluctuation | 31.22 | 12.98 | 13 | 92027 | 35810 | 50477274 |
Nail pigmentation | 31.04 | 12.98 | 12 | 92028 | 176 | 50512908 |
Illness | 30.99 | 12.98 | 4 | 92036 | 24536 | 50488548 |
Vision blurred | 30.95 | 12.98 | 60 | 91980 | 78587 | 50434497 |
Hepatic infarction | 30.88 | 12.98 | 17 | 92023 | 579 | 50512505 |
Irritability | 30.72 | 12.98 | 7 | 92033 | 28419 | 50484665 |
Influenza | 30.53 | 12.98 | 74 | 91966 | 89464 | 50423620 |
Cardiac dysfunction | 30.33 | 12.98 | 25 | 92015 | 1676 | 50511408 |
Urinary tract infection | 30.32 | 12.98 | 261 | 91779 | 223759 | 50289325 |
Cytomegalovirus viraemia | 30.22 | 12.98 | 40 | 92000 | 4669 | 50508415 |
Radiation necrosis | 30.18 | 12.98 | 14 | 92026 | 329 | 50512755 |
Nasal abscess | 30.16 | 12.98 | 11 | 92029 | 136 | 50512948 |
Hypertransaminasaemia | 30.13 | 12.98 | 35 | 92005 | 3576 | 50509508 |
Nodular regenerative hyperplasia | 29.99 | 12.98 | 13 | 92027 | 259 | 50512825 |
C-reactive protein abnormal | 29.75 | 12.98 | 7 | 92033 | 27802 | 50485282 |
Malignant transformation | 29.68 | 12.98 | 14 | 92026 | 342 | 50512742 |
Carbohydrate antigen 125 increased | 29.61 | 12.98 | 29 | 92011 | 2438 | 50510646 |
Angioedema | 29.27 | 12.98 | 16 | 92024 | 37660 | 50475424 |
Emotional distress | 29.15 | 12.98 | 8 | 92032 | 28655 | 50484429 |
Blood pressure systolic increased | 29.11 | 12.98 | 14 | 92026 | 35435 | 50477649 |
Chronic myeloid leukaemia | 29.02 | 12.98 | 27 | 92013 | 2129 | 50510955 |
Hepatotoxicity | 28.95 | 12.98 | 112 | 91928 | 27114 | 50485970 |
Gastric disorder | 28.67 | 12.98 | 9 | 92031 | 29539 | 50483545 |
Thyroid dermatopathy | 28.59 | 12.98 | 7 | 92033 | 17 | 50513067 |
Vena cava thrombosis | 28.54 | 12.98 | 26 | 92014 | 1995 | 50511089 |
Periorbital cellulitis | 28.54 | 12.98 | 16 | 92024 | 565 | 50512519 |
Acute leukaemia | 28.38 | 12.98 | 20 | 92020 | 1060 | 50512024 |
Cytogenetic abnormality | 28.27 | 12.98 | 15 | 92025 | 474 | 50512610 |
Chest pain | 28.18 | 12.98 | 197 | 91843 | 176685 | 50336399 |
Clostridium difficile infection | 28.16 | 12.98 | 106 | 91934 | 25333 | 50487751 |
Blister | 28.02 | 12.98 | 72 | 91968 | 85346 | 50427738 |
Quadriplegia | 28.00 | 12.98 | 24 | 92016 | 1699 | 50511385 |
Ototoxicity | 27.61 | 12.98 | 20 | 92020 | 1107 | 50511977 |
Agitation | 27.44 | 12.98 | 34 | 92006 | 53350 | 50459734 |
Swollen tongue | 27.28 | 12.98 | 9 | 92031 | 28621 | 50484463 |
T-cell lymphoma | 27.24 | 12.98 | 16 | 92024 | 618 | 50512466 |
Left ventricular dilatation | 27.23 | 12.98 | 14 | 92026 | 414 | 50512670 |
Leukaemic lymphoma | 27.23 | 12.98 | 9 | 92031 | 81 | 50513003 |
Product quality issue | 27.21 | 12.98 | 11 | 92029 | 30847 | 50482237 |
Bursitis | 27.03 | 12.98 | 4 | 92036 | 22131 | 50490953 |
Systolic dysfunction | 27.02 | 12.98 | 22 | 92018 | 1450 | 50511634 |
Hepatocellular injury | 26.99 | 12.98 | 106 | 91934 | 25841 | 50487243 |
B-cell lymphoma refractory | 26.84 | 12.98 | 9 | 92031 | 85 | 50512999 |
Intussusception | 26.84 | 12.98 | 14 | 92026 | 427 | 50512657 |
Clonal haematopoiesis | 26.80 | 12.98 | 6 | 92034 | 8 | 50513076 |
Infusion site streaking | 26.75 | 12.98 | 14 | 92026 | 430 | 50512654 |
Cerebral venous sinus thrombosis | 26.63 | 12.98 | 23 | 92017 | 1645 | 50511439 |
Tissue infiltration | 26.54 | 12.98 | 15 | 92025 | 538 | 50512546 |
Enterococcal infection | 26.32 | 12.98 | 46 | 91994 | 6852 | 50506232 |
Limb injury | 26.31 | 12.98 | 3 | 92037 | 20247 | 50492837 |
Vocal cord paralysis | 26.24 | 12.98 | 23 | 92017 | 1678 | 50511406 |
Hyperpyrexia | 26.20 | 12.98 | 30 | 92010 | 3019 | 50510065 |
Platelet count abnormal | 26.13 | 12.98 | 29 | 92011 | 2820 | 50510264 |
Metastases to the mediastinum | 26.00 | 12.98 | 14 | 92026 | 456 | 50512628 |
Computerised tomogram thorax | 25.97 | 12.98 | 10 | 92030 | 145 | 50512939 |
Cerebellar stroke | 25.90 | 12.98 | 11 | 92029 | 208 | 50512876 |
Blood lactate dehydrogenase abnormal | 25.90 | 12.98 | 11 | 92029 | 208 | 50512876 |
Hallucination | 25.83 | 12.98 | 28 | 92012 | 46629 | 50466455 |
Clostridium difficile colitis | 25.83 | 12.98 | 81 | 91959 | 17661 | 50495423 |
Toxic neuropathy | 25.77 | 12.98 | 13 | 92027 | 369 | 50512715 |
Invasive breast carcinoma | 25.76 | 12.98 | 15 | 92025 | 570 | 50512514 |
Metastases to soft tissue | 25.66 | 12.98 | 10 | 92030 | 150 | 50512934 |
Pulmonary alveolar haemorrhage | 25.52 | 12.98 | 34 | 92006 | 3993 | 50509091 |
Listeria sepsis | 25.29 | 12.98 | 15 | 92025 | 590 | 50512494 |
Acne | 25.22 | 12.98 | 3 | 92037 | 19592 | 50493492 |
Hyperhidrosis | 25.22 | 12.98 | 81 | 91959 | 89345 | 50423739 |
Flatulence | 25.17 | 12.98 | 11 | 92029 | 29447 | 50483637 |
Rash pruritic | 25.09 | 12.98 | 30 | 92010 | 47816 | 50465268 |
Radiation skin injury | 25.07 | 12.98 | 17 | 92023 | 846 | 50512238 |
Basal ganglion degeneration | 24.97 | 12.98 | 13 | 92027 | 395 | 50512689 |
Leukoencephalopathy | 24.94 | 12.98 | 33 | 92007 | 3850 | 50509234 |
Granulomatous liver disease | 24.90 | 12.98 | 16 | 92024 | 727 | 50512357 |
Ventricular internal diameter abnormal | 24.87 | 12.98 | 7 | 92033 | 34 | 50513050 |
Cytokine release syndrome | 24.79 | 12.98 | 51 | 91989 | 8583 | 50504501 |
Osteoporosis | 24.77 | 12.98 | 27 | 92013 | 44852 | 50468232 |
Type 2 diabetes mellitus | 24.73 | 12.98 | 16 | 92024 | 34359 | 50478725 |
General physical health deterioration | 24.72 | 12.98 | 380 | 91660 | 142054 | 50371030 |
Onycholysis | 24.70 | 12.98 | 20 | 92020 | 1308 | 50511776 |
Dry mouth | 24.68 | 12.98 | 40 | 92000 | 56138 | 50456946 |
Peripheral T-cell lymphoma unspecified | 24.68 | 12.98 | 10 | 92030 | 167 | 50512917 |
Treatment noncompliance | 24.61 | 12.98 | 12 | 92028 | 30138 | 50482946 |
Road traffic accident | 24.39 | 12.98 | 7 | 92033 | 24345 | 50488739 |
Pulse waveform abnormal | 24.20 | 12.98 | 8 | 92032 | 72 | 50513012 |
Ankle brachial index decreased | 24.10 | 12.98 | 8 | 92032 | 73 | 50513011 |
Abdominal compartment syndrome | 24.04 | 12.98 | 14 | 92026 | 532 | 50512552 |
Coronary artery disease | 24.01 | 12.98 | 12 | 92028 | 29714 | 50483370 |
International normalised ratio increased | 23.77 | 12.98 | 26 | 92014 | 43126 | 50469958 |
Carotid intima-media thickness increased | 23.73 | 12.98 | 8 | 92032 | 77 | 50513007 |
Bacterial sepsis | 23.67 | 12.98 | 31 | 92009 | 3581 | 50509503 |
Hyperferritinaemia | 23.60 | 12.98 | 9 | 92031 | 127 | 50512957 |
Left atrial enlargement | 23.58 | 12.98 | 11 | 92029 | 262 | 50512822 |
Mediastinitis | 23.55 | 12.98 | 10 | 92030 | 189 | 50512895 |
Chronic obstructive pulmonary disease | 23.52 | 12.98 | 38 | 92002 | 53397 | 50459687 |
Primary immunodeficiency syndrome | 23.50 | 12.98 | 7 | 92033 | 43 | 50513041 |
Joint range of motion decreased | 23.42 | 12.98 | 3 | 92037 | 18509 | 50494575 |
Osteolysis | 23.40 | 12.98 | 26 | 92014 | 2531 | 50510553 |
Myeloproliferative neoplasm | 23.34 | 12.98 | 13 | 92027 | 453 | 50512631 |
Ear infection | 23.32 | 12.98 | 9 | 92031 | 25961 | 50487123 |
Klebsiella bacteraemia | 23.26 | 12.98 | 19 | 92021 | 1258 | 50511826 |
Aggression | 23.22 | 12.98 | 5 | 92035 | 21111 | 50491973 |
Abortion spontaneous | 23.20 | 12.98 | 25 | 92015 | 41747 | 50471337 |
Increased liver stiffness | 23.10 | 12.98 | 5 | 92035 | 5 | 50513079 |
Cardio-respiratory arrest | 23.10 | 12.98 | 39 | 92001 | 53853 | 50459231 |
Deep vein thrombosis | 23.05 | 12.98 | 219 | 91821 | 73085 | 50439999 |
Metastases to chest wall | 23.03 | 12.98 | 13 | 92027 | 465 | 50512619 |
Fanconi syndrome | 23.03 | 12.98 | 18 | 92022 | 1118 | 50511966 |
Dry eye | 23.00 | 12.98 | 15 | 92025 | 32080 | 50481004 |
Abnormal behaviour | 23.00 | 12.98 | 4 | 92036 | 19654 | 50493430 |
Disseminated intravascular coagulation | 22.93 | 12.98 | 76 | 91964 | 17059 | 50496025 |
Refractory cytopenia with multilineage dysplasia | 22.86 | 12.98 | 9 | 92031 | 139 | 50512945 |
Cardiac ventricular thrombosis | 22.83 | 12.98 | 13 | 92027 | 473 | 50512611 |
Depressed level of consciousness | 22.82 | 12.98 | 37 | 92003 | 51916 | 50461168 |
Rhinovirus infection | 22.65 | 12.98 | 30 | 92010 | 3504 | 50509580 |
Swelling face | 22.60 | 12.98 | 38 | 92002 | 52557 | 50460527 |
Proteinuria | 22.55 | 12.98 | 74 | 91966 | 16523 | 50496561 |
Heart rate irregular | 22.52 | 12.98 | 4 | 92036 | 19356 | 50493728 |
Large intestine perforation | 22.38 | 12.98 | 45 | 91995 | 7449 | 50505635 |
Sleep disorder | 22.28 | 12.98 | 44 | 91996 | 57239 | 50455845 |
Pseudocirrhosis | 22.19 | 12.98 | 14 | 92026 | 616 | 50512468 |
Drug reaction with eosinophilia and systemic symptoms | 22.18 | 12.98 | 12 | 92028 | 28412 | 50484672 |
Blood magnesium decreased | 22.16 | 12.98 | 57 | 91983 | 11103 | 50501981 |
Hypoaesthesia | 22.14 | 12.98 | 138 | 91902 | 127119 | 50385965 |
Acute biphenotypic leukaemia | 22.12 | 12.98 | 7 | 92033 | 54 | 50513030 |
Crying | 22.11 | 12.98 | 5 | 92035 | 20411 | 50492673 |
Joint ankylosis | 22.08 | 12.98 | 15 | 92025 | 749 | 50512335 |
Candida infection | 22.01 | 12.98 | 93 | 91947 | 23430 | 50489654 |
Sinus polyp | 21.98 | 12.98 | 11 | 92029 | 307 | 50512777 |
Anastomotic leak | 21.92 | 12.98 | 12 | 92028 | 404 | 50512680 |
Gait inability | 21.89 | 12.98 | 21 | 92019 | 37006 | 50476078 |
Uterine enlargement | 21.85 | 12.98 | 17 | 92023 | 1049 | 50512035 |
Metastases to pancreas | 21.79 | 12.98 | 10 | 92030 | 229 | 50512855 |
Aspergillus infection | 21.63 | 12.98 | 42 | 91998 | 6779 | 50506305 |
Non-cirrhotic portal hypertension | 21.55 | 12.98 | 9 | 92031 | 163 | 50512921 |
Diabetes mellitus | 21.46 | 12.98 | 35 | 92005 | 48998 | 50464086 |
Subdural hygroma | 21.44 | 12.98 | 10 | 92030 | 238 | 50512846 |
Combined immunodeficiency | 21.43 | 12.98 | 8 | 92032 | 106 | 50512978 |
BRCA2 gene mutation | 21.28 | 12.98 | 7 | 92033 | 62 | 50513022 |
Mantle cell lymphoma | 21.14 | 12.98 | 12 | 92028 | 434 | 50512650 |
Basal cell carcinoma | 21.13 | 12.98 | 8 | 92032 | 23348 | 50489736 |
Nervousness | 21.10 | 12.98 | 12 | 92028 | 27639 | 50485445 |
Amputation stump pain | 21.01 | 12.98 | 6 | 92034 | 31 | 50513053 |
Dysplasia | 21.01 | 12.98 | 14 | 92026 | 677 | 50512407 |
Acute monocytic leukaemia | 20.89 | 12.98 | 7 | 92033 | 66 | 50513018 |
Gastric stenosis | 20.89 | 12.98 | 7 | 92033 | 66 | 50513018 |
Hip arthroplasty | 20.77 | 12.98 | 15 | 92025 | 30414 | 50482670 |
Drug clearance decreased | 20.73 | 12.98 | 17 | 92023 | 1132 | 50511952 |
Colitis ulcerative | 20.69 | 12.98 | 3 | 92037 | 16851 | 50496233 |
Paraparesis | 20.66 | 12.98 | 22 | 92018 | 2042 | 50511042 |
Mucormycosis | 20.61 | 12.98 | 24 | 92016 | 2459 | 50510625 |
Bone marrow infiltration | 20.60 | 12.98 | 12 | 92028 | 456 | 50512628 |
Restlessness | 20.58 | 12.98 | 10 | 92030 | 25163 | 50487921 |
Geotrichum infection | 20.56 | 12.98 | 12 | 92028 | 458 | 50512626 |
Epstein-Barr virus associated lymphoproliferative disorder | 20.54 | 12.98 | 20 | 92020 | 1669 | 50511415 |
Acute hepatic failure | 20.50 | 12.98 | 69 | 91971 | 15608 | 50497476 |
Opsoclonus myoclonus | 20.47 | 12.98 | 8 | 92032 | 121 | 50512963 |
Administration site extravasation | 20.46 | 12.98 | 14 | 92026 | 707 | 50512377 |
Brain oedema | 20.39 | 12.98 | 59 | 91981 | 12311 | 50500773 |
Cerebellar haemangioma | 20.35 | 12.98 | 7 | 92033 | 72 | 50513012 |
Vulvovaginal inflammation | 20.26 | 12.98 | 13 | 92027 | 589 | 50512495 |
Tumour necrosis | 20.24 | 12.98 | 14 | 92026 | 720 | 50512364 |
Pharyngeal inflammation | 20.07 | 12.98 | 13 | 92027 | 599 | 50512485 |
Liver function test abnormal | 20.02 | 12.98 | 31 | 92009 | 44308 | 50468776 |
Blood pressure decreased | 20.02 | 12.98 | 45 | 91995 | 55864 | 50457220 |
Toxic erythema of chemotherapy | 20.00 | 12.98 | 8 | 92032 | 129 | 50512955 |
Mucoepidermoid carcinoma | 19.98 | 12.98 | 6 | 92034 | 38 | 50513046 |
Duodenal stenosis | 19.96 | 12.98 | 12 | 92028 | 484 | 50512600 |
Lip swelling | 19.96 | 12.98 | 10 | 92030 | 24726 | 50488358 |
Sciatica | 19.89 | 12.98 | 7 | 92033 | 21375 | 50491709 |
Dysaesthesia | 19.89 | 12.98 | 29 | 92011 | 3706 | 50509378 |
Therapy interrupted | 19.80 | 12.98 | 6 | 92034 | 20146 | 50492938 |
Eye swelling | 19.79 | 12.98 | 6 | 92034 | 20138 | 50492946 |
Pulmonary vein stenosis | 19.77 | 12.98 | 7 | 92033 | 79 | 50513005 |
Abdominal abscess | 19.74 | 12.98 | 30 | 92010 | 3978 | 50509106 |
Respiratory distress | 19.46 | 12.98 | 108 | 91932 | 30381 | 50482703 |
Eye pain | 19.45 | 12.98 | 14 | 92026 | 28435 | 50484649 |
Red blood cell sedimentation rate increased | 19.44 | 12.98 | 15 | 92025 | 29401 | 50483683 |
Acute respiratory distress syndrome | 19.42 | 12.98 | 83 | 91957 | 21016 | 50492068 |
Jejunal stenosis | 19.35 | 12.98 | 6 | 92034 | 43 | 50513041 |
Transaminases | 19.30 | 12.98 | 7 | 92033 | 85 | 50512999 |
Dementia | 19.28 | 12.98 | 3 | 92037 | 15994 | 50497090 |
Mood swings | 19.21 | 12.98 | 3 | 92037 | 15951 | 50497133 |
Ovarian cancer | 19.21 | 12.98 | 34 | 92006 | 5115 | 50507969 |
Prescribed underdose | 19.21 | 12.98 | 3 | 92037 | 15946 | 50497138 |
Influenza like illness | 19.18 | 12.98 | 48 | 91992 | 57411 | 50455673 |
Vulvovaginitis | 19.17 | 12.98 | 10 | 92030 | 305 | 50512779 |
Weight decreased | 19.16 | 12.98 | 285 | 91755 | 220960 | 50292124 |
Leukaemia cutis | 19.08 | 12.98 | 7 | 92033 | 88 | 50512996 |
PIK3CA-activated mutation | 19.00 | 12.98 | 14 | 92026 | 796 | 50512288 |
Pleuroparenchymal fibroelastosis | 18.96 | 12.98 | 5 | 92035 | 18 | 50513066 |
Small intestinal perforation | 18.92 | 12.98 | 17 | 92023 | 1281 | 50511803 |
Mitral valve disease | 18.90 | 12.98 | 21 | 92019 | 2045 | 50511039 |
Peritonitis viral | 18.77 | 12.98 | 6 | 92034 | 48 | 50513036 |
Breast neoplasm | 18.76 | 12.98 | 17 | 92023 | 1296 | 50511788 |
Atypical haemolytic uraemic syndrome | 18.68 | 12.98 | 12 | 92028 | 545 | 50512539 |
Cytomegalovirus chorioretinitis | 18.62 | 12.98 | 18 | 92022 | 1489 | 50511595 |
Subileus | 18.58 | 12.98 | 24 | 92016 | 2735 | 50510349 |
Panic attack | 18.57 | 12.98 | 6 | 92034 | 19336 | 50493748 |
Chronic hepatitis | 18.54 | 12.98 | 14 | 92026 | 826 | 50512258 |
Human rhinovirus test positive | 18.52 | 12.98 | 8 | 92032 | 158 | 50512926 |
Neonatal lupus erythematosus | 18.48 | 12.98 | 4 | 92036 | 4 | 50513080 |
Serotonin syndrome | 18.47 | 12.98 | 11 | 92029 | 24702 | 50488382 |
Intervertebral disc protrusion | 18.42 | 12.98 | 7 | 92033 | 20386 | 50492698 |
Bradycardia | 18.41 | 12.98 | 58 | 91982 | 64368 | 50448716 |
Staphylococcal sepsis | 18.39 | 12.98 | 40 | 92000 | 6996 | 50506088 |
Osteosarcoma metastatic | 18.35 | 12.98 | 5 | 92035 | 21 | 50513063 |
Paranasal sinus mucosal hypertrophy | 18.35 | 12.98 | 5 | 92035 | 21 | 50513063 |
Malignant ascites | 18.35 | 12.98 | 14 | 92026 | 839 | 50512245 |
Gallbladder disorder | 18.34 | 12.98 | 4 | 92036 | 16738 | 50496346 |
Liver function test increased | 18.31 | 12.98 | 12 | 92028 | 25594 | 50487490 |
Tendonitis | 18.28 | 12.98 | 4 | 92036 | 16701 | 50496383 |
Atrial fibrillation | 18.25 | 12.98 | 273 | 91767 | 101472 | 50411612 |
Enterocutaneous fistula | 18.24 | 12.98 | 16 | 92024 | 1168 | 50511916 |
Diarrhoea haemorrhagic | 18.23 | 12.98 | 42 | 91998 | 7633 | 50505451 |
Renal disorder | 18.20 | 12.98 | 14 | 92026 | 27491 | 50485593 |
Fungal oesophagitis | 18.20 | 12.98 | 12 | 92028 | 570 | 50512514 |
Central nervous system enteroviral infection | 18.17 | 12.98 | 5 | 92035 | 22 | 50513062 |
Liver abscess | 18.16 | 12.98 | 23 | 92017 | 2570 | 50510514 |
Infection | 18.12 | 12.98 | 427 | 91613 | 172527 | 50340557 |
Triple negative breast cancer | 18.09 | 12.98 | 7 | 92033 | 103 | 50512981 |
Femur fracture | 18.08 | 12.98 | 25 | 92015 | 37439 | 50475645 |
Dysstasia | 18.07 | 12.98 | 5 | 92035 | 17814 | 50495270 |
Secondary cerebellar degeneration | 17.96 | 12.98 | 6 | 92034 | 56 | 50513028 |
Enterocolitis | 17.93 | 12.98 | 38 | 92002 | 6529 | 50506555 |
Anaesthesia | 17.92 | 12.98 | 10 | 92030 | 350 | 50512734 |
Inflammation | 17.88 | 12.98 | 49 | 91991 | 56863 | 50456221 |
Tooth disorder | 17.81 | 12.98 | 11 | 92029 | 24217 | 50488867 |
Urethritis | 17.67 | 12.98 | 9 | 92031 | 261 | 50512823 |
Inflammatory myofibroblastic tumour | 17.64 | 12.98 | 5 | 92035 | 25 | 50513059 |
Product prescribing error | 17.64 | 12.98 | 8 | 92032 | 20953 | 50492131 |
Hormone receptor positive breast cancer | 17.62 | 12.98 | 11 | 92029 | 475 | 50512609 |
Head injury | 17.52 | 12.98 | 11 | 92029 | 24009 | 50489075 |
Therapy cessation | 17.52 | 12.98 | 13 | 92027 | 25998 | 50487086 |
Acute pulmonary oedema | 17.52 | 12.98 | 40 | 92000 | 7227 | 50505857 |
Drug dependence | 17.49 | 12.98 | 7 | 92033 | 19752 | 50493332 |
Injection site rash | 17.44 | 12.98 | 4 | 92036 | 16173 | 50496911 |
Hip fracture | 17.42 | 12.98 | 13 | 92027 | 25918 | 50487166 |
Lactic acidosis | 17.40 | 12.98 | 21 | 92019 | 33334 | 50479750 |
Pneumonia | 17.40 | 12.98 | 848 | 91192 | 377553 | 50135531 |
Oesophageal candidiasis | 17.38 | 12.98 | 32 | 92008 | 4962 | 50508122 |
Synovial sarcoma | 17.33 | 12.98 | 5 | 92035 | 27 | 50513057 |
Artificial menopause | 17.33 | 12.98 | 5 | 92035 | 27 | 50513057 |
Nightmare | 17.30 | 12.98 | 4 | 92036 | 16082 | 50497002 |
Trichodysplasia spinulosa | 17.29 | 12.98 | 11 | 92029 | 491 | 50512593 |
Rhinorrhoea | 17.29 | 12.98 | 43 | 91997 | 51540 | 50461544 |
Vomiting | 17.28 | 12.98 | 1013 | 91027 | 459745 | 50053339 |
Sarcoidosis | 17.28 | 12.98 | 32 | 92008 | 4985 | 50508099 |
Oral fungal infection | 17.27 | 12.98 | 22 | 92018 | 2473 | 50510611 |
Primary mediastinal large B-cell lymphoma recurrent | 17.25 | 12.98 | 6 | 92034 | 64 | 50513020 |
Sinus disorder | 17.24 | 12.98 | 6 | 92034 | 18452 | 50494632 |
Cardiac tamponade | 17.17 | 12.98 | 29 | 92011 | 4203 | 50508881 |
Accidental overdose | 17.16 | 12.98 | 7 | 92033 | 19526 | 50493558 |
Pneumonia influenzal | 17.15 | 12.98 | 17 | 92023 | 1450 | 50511634 |
Seasonal allergy | 17.14 | 12.98 | 3 | 92037 | 14673 | 50498411 |
Hyperbilirubinaemia | 17.10 | 12.98 | 47 | 91993 | 9523 | 50503561 |
Abdominal neoplasm | 17.09 | 12.98 | 9 | 92031 | 280 | 50512804 |
Stem cell transplant | 17.09 | 12.98 | 18 | 92022 | 1650 | 50511434 |
Eye irritation | 17.03 | 12.98 | 5 | 92035 | 17135 | 50495949 |
Myasthenic syndrome | 17.01 | 12.98 | 8 | 92032 | 194 | 50512890 |
Device dislocation | 16.95 | 12.98 | 9 | 92031 | 21537 | 50491547 |
Herpes zoster meningoencephalitis | 16.94 | 12.98 | 9 | 92031 | 285 | 50512799 |
Mediastinum neoplasm | 16.92 | 12.98 | 6 | 92034 | 68 | 50513016 |
Rectal fissure | 16.82 | 12.98 | 11 | 92029 | 515 | 50512569 |
Disorientation | 16.81 | 12.98 | 24 | 92016 | 35460 | 50477624 |
Orthopnoea | 16.80 | 12.98 | 34 | 92006 | 5655 | 50507429 |
Glaucoma | 16.67 | 12.98 | 4 | 92036 | 15682 | 50497402 |
Atrial flutter | 16.62 | 12.98 | 44 | 91996 | 8719 | 50504365 |
Metastases to abdominal cavity | 16.55 | 12.98 | 10 | 92030 | 407 | 50512677 |
Ventricular remodelling | 16.55 | 12.98 | 4 | 92036 | 9 | 50513075 |
Failure to thrive | 16.45 | 12.98 | 36 | 92004 | 6322 | 50506762 |
Heavy menstrual bleeding | 16.44 | 12.98 | 4 | 92036 | 15533 | 50497551 |
Pleural disorder | 16.41 | 12.98 | 11 | 92029 | 537 | 50512547 |
Venous thrombosis limb | 16.41 | 12.98 | 22 | 92018 | 2600 | 50510484 |
Toxic encephalopathy | 16.33 | 12.98 | 33 | 92007 | 5482 | 50507602 |
Granulocytopenia | 16.33 | 12.98 | 32 | 92008 | 5199 | 50507885 |
Poor quality sleep | 16.28 | 12.98 | 5 | 92035 | 16641 | 50496443 |
Febrile infection | 16.27 | 12.98 | 15 | 92025 | 1169 | 50511915 |
BK virus infection | 16.26 | 12.98 | 23 | 92017 | 2858 | 50510226 |
Jejunal ulcer perforation | 16.22 | 12.98 | 5 | 92035 | 35 | 50513049 |
Granulomatous pneumonitis | 16.22 | 12.98 | 5 | 92035 | 35 | 50513049 |
Enterovirus test positive | 16.22 | 12.98 | 7 | 92033 | 138 | 50512946 |
Lung disorder | 16.21 | 12.98 | 138 | 91902 | 44661 | 50468423 |
Portal hypertension | 16.15 | 12.98 | 25 | 92015 | 3367 | 50509717 |
Haematoma | 16.14 | 12.98 | 19 | 92021 | 30491 | 50482593 |
VIth nerve paresis | 16.11 | 12.98 | 6 | 92034 | 79 | 50513005 |
Renal tubular disorder | 16.10 | 12.98 | 21 | 92019 | 2416 | 50510668 |
Pregnancy | 16.10 | 12.98 | 18 | 92022 | 29559 | 50483525 |
Antithrombin III decreased | 16.09 | 12.98 | 8 | 92032 | 220 | 50512864 |
Transient ischaemic attack | 16.05 | 12.98 | 21 | 92019 | 32189 | 50480895 |
Acute hepatitis C | 16.04 | 12.98 | 6 | 92034 | 80 | 50513004 |
Low birth weight baby | 16.02 | 12.98 | 34 | 92006 | 5847 | 50507237 |
Movement disorder | 16.02 | 12.98 | 6 | 92034 | 17626 | 50495458 |
Kidney infection | 16.02 | 12.98 | 7 | 92033 | 18739 | 50494345 |
Aplastic anaemia | 15.98 | 12.98 | 40 | 92000 | 7663 | 50505421 |
Fungaemia | 15.96 | 12.98 | 19 | 92021 | 1993 | 50511091 |
Lethargy | 15.95 | 12.98 | 42 | 91998 | 49390 | 50463694 |
Mucoepidermoid carcinoma of salivary gland | 15.93 | 12.98 | 3 | 92037 | 0 | 50513084 |
Maternal exposure during pregnancy | 15.92 | 12.98 | 200 | 91840 | 159578 | 50353506 |
Intestinal obstruction | 15.88 | 12.98 | 92 | 91948 | 26291 | 50486793 |
Syphilis | 15.81 | 12.98 | 7 | 92033 | 147 | 50512937 |
Meningitis streptococcal | 15.81 | 12.98 | 7 | 92033 | 147 | 50512937 |
Cholelithiasis | 15.79 | 12.98 | 28 | 92012 | 37945 | 50475139 |
Leukoplakia oral | 15.72 | 12.98 | 7 | 92033 | 149 | 50512935 |
Cytology abnormal | 15.72 | 12.98 | 4 | 92036 | 12 | 50513072 |
Thrombophlebitis | 15.72 | 12.98 | 27 | 92013 | 3966 | 50509118 |
Salmonella sepsis | 15.70 | 12.98 | 8 | 92032 | 232 | 50512852 |
Neurological decompensation | 15.69 | 12.98 | 20 | 92020 | 2250 | 50510834 |
Dermatitis bullous | 15.68 | 12.98 | 38 | 92002 | 7135 | 50505949 |
Pleural neoplasm | 15.67 | 12.98 | 8 | 92032 | 233 | 50512851 |
Pyloric stenosis | 15.65 | 12.98 | 9 | 92031 | 334 | 50512750 |
Blood stem cell transplant failure | 15.64 | 12.98 | 7 | 92033 | 151 | 50512933 |
Metastases to retroperitoneum | 15.51 | 12.98 | 7 | 92033 | 154 | 50512930 |
Faeces discoloured | 15.48 | 12.98 | 5 | 92035 | 16119 | 50496965 |
Acral peeling skin syndrome | 15.48 | 12.98 | 4 | 92036 | 13 | 50513071 |
Metastases to ovary | 15.48 | 12.98 | 9 | 92031 | 341 | 50512743 |
Hypersensitivity pneumonitis | 15.33 | 12.98 | 20 | 92020 | 2302 | 50510782 |
Pulmonary artery stenosis | 15.27 | 12.98 | 7 | 92033 | 160 | 50512924 |
Oedema peripheral | 15.27 | 12.98 | 199 | 91841 | 157762 | 50355322 |
Pulmonary mass | 15.26 | 12.98 | 71 | 91969 | 18634 | 50494450 |
Vessel puncture site bruise | 15.22 | 12.98 | 9 | 92031 | 352 | 50512732 |
Tumour marker increased | 15.16 | 12.98 | 26 | 92014 | 3814 | 50509270 |
Depressed mood | 15.16 | 12.98 | 24 | 92016 | 33999 | 50479085 |
Rash erythematous | 15.14 | 12.98 | 25 | 92015 | 34827 | 50478257 |
Laboratory test abnormal | 15.12 | 12.98 | 12 | 92028 | 23196 | 50489888 |
Sputum discoloured | 15.08 | 12.98 | 3 | 92037 | 13392 | 50499692 |
Listeria encephalitis | 14.99 | 12.98 | 8 | 92032 | 256 | 50512828 |
Acute erythroid leukaemia | 14.93 | 12.98 | 5 | 92035 | 47 | 50513037 |
Haemorrhage intracranial | 14.91 | 12.98 | 53 | 91987 | 12321 | 50500763 |
Carbohydrate antigen 15-3 increased | 14.90 | 12.98 | 14 | 92026 | 1118 | 50511966 |
Pulmonary haemorrhage | 14.84 | 12.98 | 35 | 92005 | 6457 | 50506627 |
Beta 2 microglobulin decreased | 14.84 | 12.98 | 4 | 92036 | 16 | 50513068 |
Necrosis | 14.82 | 12.98 | 29 | 92011 | 4707 | 50508377 |
Venous thrombosis | 14.78 | 12.98 | 28 | 92012 | 4438 | 50508646 |
Throat irritation | 14.77 | 12.98 | 20 | 92020 | 30219 | 50482865 |
Rhabdomyosarcoma | 14.77 | 12.98 | 6 | 92034 | 101 | 50512983 |
IIIrd nerve paralysis | 14.76 | 12.98 | 11 | 92029 | 636 | 50512448 |
Blood potassium decreased | 14.69 | 12.98 | 28 | 92012 | 36917 | 50476167 |
Diabetes mellitus inadequate control | 14.68 | 12.98 | 3 | 92037 | 13142 | 50499942 |
Medication error | 14.68 | 12.98 | 27 | 92013 | 36077 | 50477007 |
Cerebral haemangioma | 14.66 | 12.98 | 6 | 92034 | 103 | 50512981 |
Metastases to vagina | 14.64 | 12.98 | 4 | 92036 | 17 | 50513067 |
Necrotising colitis | 14.62 | 12.98 | 10 | 92030 | 505 | 50512579 |
Pseudomonas infection | 14.61 | 12.98 | 44 | 91996 | 9386 | 50503698 |
Hypoglossal nerve paresis | 14.50 | 12.98 | 6 | 92034 | 106 | 50512978 |
Joint effusion | 14.49 | 12.98 | 3 | 92037 | 13018 | 50500066 |
B-lymphocyte count abnormal | 14.48 | 12.98 | 5 | 92035 | 52 | 50513032 |
Epstein Barr virus positive mucocutaneous ulcer | 14.47 | 12.98 | 9 | 92031 | 386 | 50512698 |
Eczema | 14.47 | 12.98 | 12 | 92028 | 22690 | 50490394 |
Right ventricular dysfunction | 14.45 | 12.98 | 16 | 92024 | 1552 | 50511532 |
Chronic hepatitis B | 14.44 | 12.98 | 7 | 92033 | 182 | 50512902 |
Alopecia areata | 14.44 | 12.98 | 15 | 92025 | 1353 | 50511731 |
Retroperitoneal mass | 14.40 | 12.98 | 6 | 92034 | 108 | 50512976 |
Respiratory tract congestion | 14.37 | 12.98 | 4 | 92036 | 14195 | 50498889 |
Hepatic lesion | 14.35 | 12.98 | 26 | 92014 | 3982 | 50509102 |
Skin mass | 14.35 | 12.98 | 30 | 92010 | 5105 | 50507979 |
Tachycardia induced cardiomyopathy | 14.32 | 12.98 | 5 | 92035 | 54 | 50513030 |
Ocular lymphoma | 14.32 | 12.98 | 5 | 92035 | 54 | 50513030 |
Photosensitivity reaction | 14.31 | 12.98 | 3 | 92037 | 12908 | 50500176 |
Metastases to stomach | 14.30 | 12.98 | 7 | 92033 | 186 | 50512898 |
Subclavian vein thrombosis | 14.29 | 12.98 | 17 | 92023 | 1782 | 50511302 |
Metastatic neoplasm | 14.28 | 12.98 | 25 | 92015 | 3729 | 50509355 |
Diverticulitis | 14.23 | 12.98 | 24 | 92016 | 33158 | 50479926 |
Hypokalaemia | 14.21 | 12.98 | 232 | 91808 | 87760 | 50425324 |
Encephalitis viral | 14.21 | 12.98 | 16 | 92024 | 1581 | 50511503 |
Sneezing | 14.13 | 12.98 | 4 | 92036 | 14040 | 50499044 |
Malignant neoplasm of orbit | 14.12 | 12.98 | 4 | 92036 | 20 | 50513064 |
Lymphadenopathy mediastinal | 14.11 | 12.98 | 20 | 92020 | 2491 | 50510593 |
Dermatitis allergic | 14.01 | 12.98 | 3 | 92037 | 12717 | 50500367 |
Chronic myelomonocytic leukaemia | 13.95 | 12.98 | 8 | 92032 | 295 | 50512789 |
Vascular compression | 13.91 | 12.98 | 6 | 92034 | 118 | 50512966 |
Orthostatic hypotension | 13.90 | 12.98 | 20 | 92020 | 29461 | 50483623 |
Obliterative bronchiolitis | 13.88 | 12.98 | 17 | 92023 | 1836 | 50511248 |
Chondrosarcoma metastatic | 13.86 | 12.98 | 3 | 92037 | 3 | 50513081 |
Lung adenocarcinoma | 13.78 | 12.98 | 26 | 92014 | 4108 | 50508976 |
Thrombocytopenic purpura | 13.76 | 12.98 | 14 | 92026 | 1232 | 50511852 |
Leukaemia recurrent | 13.69 | 12.98 | 14 | 92026 | 1240 | 50511844 |
Feeling hot | 13.67 | 12.98 | 32 | 92008 | 39170 | 50473914 |
Hepatic calcification | 13.65 | 12.98 | 4 | 92036 | 23 | 50513061 |
Peripheral sensorimotor neuropathy | 13.61 | 12.98 | 14 | 92026 | 1248 | 50511836 |
Adverse event | 13.51 | 12.98 | 38 | 92002 | 43725 | 50469359 |
Hepatitis C RNA increased | 13.51 | 12.98 | 6 | 92034 | 127 | 50512957 |
Restless legs syndrome | 13.48 | 12.98 | 6 | 92034 | 15891 | 50497193 |
Upper limb fracture | 13.45 | 12.98 | 6 | 92034 | 15867 | 50497217 |
Peritoneal disorder | 13.43 | 12.98 | 9 | 92031 | 439 | 50512645 |
Lymphoproliferative disorder | 13.42 | 12.98 | 21 | 92019 | 2856 | 50510228 |
Mucosal erosion | 13.38 | 12.98 | 14 | 92026 | 1273 | 50511811 |
Hydronephrosis | 13.37 | 12.98 | 40 | 92000 | 8501 | 50504583 |
Mediastinal fibrosis | 13.37 | 12.98 | 4 | 92036 | 25 | 50513059 |
Lymph node pain | 13.31 | 12.98 | 14 | 92026 | 1281 | 50511803 |
Coronary ostial stenosis | 13.28 | 12.98 | 5 | 92035 | 68 | 50513016 |
Pneumonia cytomegaloviral | 13.25 | 12.98 | 17 | 92023 | 1924 | 50511160 |
Hyperkalaemia | 13.24 | 12.98 | 44 | 91996 | 48045 | 50465039 |
Corneal graft rejection | 13.23 | 12.98 | 4 | 92036 | 26 | 50513058 |
Spinal cord compression | 13.21 | 12.98 | 24 | 92016 | 3685 | 50509399 |
Sinus tachycardia | 13.20 | 12.98 | 75 | 91965 | 21279 | 50491805 |
Chemotherapeutic drug level increased | 13.17 | 12.98 | 6 | 92034 | 135 | 50512949 |
Cyst | 13.17 | 12.98 | 3 | 92037 | 12184 | 50500900 |
Paronychia | 13.15 | 12.98 | 27 | 92013 | 4537 | 50508547 |
Tachypnoea | 13.15 | 12.98 | 57 | 91983 | 14520 | 50498564 |
Bladder perforation | 13.13 | 12.98 | 6 | 92034 | 136 | 50512948 |
Rectal haemorrhage | 13.03 | 12.98 | 32 | 92008 | 38526 | 50474558 |
Ventricular asystole | 13.02 | 12.98 | 5 | 92035 | 72 | 50513012 |
Postictal state | 12.99 | 12.98 | 12 | 92028 | 938 | 50512146 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Febrile neutropenia | 3347.88 | 13.36 | 2480 | 67928 | 109760 | 29394359 |
Neutropenia | 1146.26 | 13.36 | 1484 | 68924 | 130227 | 29373892 |
Product use in unapproved indication | 935.73 | 13.36 | 1091 | 69317 | 85784 | 29418335 |
Off label use | 815.86 | 13.36 | 2032 | 68376 | 298768 | 29205351 |
Diffuse large B-cell lymphoma recurrent | 590.25 | 13.36 | 225 | 70183 | 2372 | 29501747 |
Mucosal inflammation | 585.43 | 13.36 | 532 | 69876 | 31063 | 29473056 |
Hepatitis B | 554.75 | 13.36 | 268 | 70140 | 5229 | 29498890 |
Second primary malignancy | 552.92 | 13.36 | 285 | 70123 | 6420 | 29497699 |
Haematotoxicity | 530.18 | 13.36 | 277 | 70131 | 6422 | 29497697 |
Cardiotoxicity | 486.91 | 13.36 | 234 | 70174 | 4510 | 29499609 |
Myelosuppression | 467.26 | 13.36 | 316 | 70092 | 11911 | 29492208 |
Myelodysplastic syndrome | 462.03 | 13.36 | 364 | 70044 | 17430 | 29486689 |
Acute myeloid leukaemia | 437.80 | 13.36 | 342 | 70066 | 16171 | 29487948 |
Hepatitis B reactivation | 417.73 | 13.36 | 187 | 70221 | 3042 | 29501077 |
Bone marrow failure | 403.62 | 13.36 | 407 | 70001 | 27042 | 29477077 |
Disease progression | 397.88 | 13.36 | 705 | 69703 | 81211 | 29422908 |
Tumour lysis syndrome | 334.75 | 13.36 | 272 | 70136 | 13612 | 29490507 |
Pancytopenia | 297.37 | 13.36 | 629 | 69779 | 82539 | 29421580 |
Thrombocytopenia | 291.99 | 13.36 | 841 | 69567 | 133982 | 29370137 |
Febrile bone marrow aplasia | 264.24 | 13.36 | 183 | 70225 | 7168 | 29496951 |
Pneumocystis jirovecii pneumonia | 245.08 | 13.36 | 248 | 70160 | 16531 | 29487588 |
Neutropenic sepsis | 233.85 | 13.36 | 206 | 70202 | 11521 | 29492598 |
Leukopenia | 232.33 | 13.36 | 447 | 69961 | 54756 | 29449363 |
Neutrophil count decreased | 228.19 | 13.36 | 388 | 70020 | 43179 | 29460940 |
Progressive multifocal leukoencephalopathy | 221.14 | 13.36 | 176 | 70232 | 8543 | 29495576 |
Cytomegalovirus chorioretinitis | 217.22 | 13.36 | 120 | 70288 | 3118 | 29501001 |
Acquired gene mutation | 215.91 | 13.36 | 89 | 70319 | 1169 | 29502950 |
Diffuse large B-cell lymphoma refractory | 209.91 | 13.36 | 80 | 70328 | 842 | 29503277 |
Therapy partial responder | 209.68 | 13.36 | 139 | 70269 | 5060 | 29499059 |
Cytopenia | 198.20 | 13.36 | 174 | 70234 | 9685 | 29494434 |
Fall | 195.12 | 13.36 | 89 | 70319 | 177089 | 29327030 |
Product dose omission issue | 185.38 | 13.36 | 11 | 70397 | 96372 | 29407747 |
Neoplasm progression | 183.52 | 13.36 | 224 | 70184 | 18388 | 29485731 |
Pyrexia | 173.19 | 13.36 | 1223 | 69185 | 286399 | 29217720 |
Septic shock | 161.78 | 13.36 | 417 | 69991 | 62143 | 29441976 |
Posterior reversible encephalopathy syndrome | 159.90 | 13.36 | 148 | 70260 | 8828 | 29495291 |
Mantle cell lymphoma recurrent | 157.25 | 13.36 | 55 | 70353 | 443 | 29503676 |
B-cell lymphoma recurrent | 152.49 | 13.36 | 57 | 70351 | 566 | 29503553 |
Cardiomyopathy | 137.78 | 13.36 | 173 | 70235 | 14614 | 29489505 |
Rash | 132.75 | 13.36 | 154 | 70254 | 189665 | 29314454 |
Malignant neoplasm progression | 132.62 | 13.36 | 432 | 69976 | 73427 | 29430692 |
Neuropathy peripheral | 131.66 | 13.36 | 420 | 69988 | 70607 | 29433512 |
Dizziness | 131.46 | 13.36 | 155 | 70253 | 189529 | 29314590 |
Sepsis | 129.01 | 13.36 | 675 | 69733 | 142007 | 29362112 |
Myocardial infarction | 128.33 | 13.36 | 51 | 70357 | 110245 | 29393874 |
Arthralgia | 123.92 | 13.36 | 91 | 70317 | 139526 | 29364593 |
Polyneuropathy | 122.62 | 13.36 | 148 | 70260 | 12004 | 29492115 |
Lymphadenopathy | 120.52 | 13.36 | 215 | 70193 | 24834 | 29479285 |
Anxiety | 117.98 | 13.36 | 29 | 70379 | 85336 | 29418783 |
Ejection fraction decreased | 110.88 | 13.36 | 162 | 70246 | 15816 | 29488303 |
Diffuse large B-cell lymphoma | 110.85 | 13.36 | 103 | 70305 | 6173 | 29497946 |
Cytomegalovirus infection | 110.08 | 13.36 | 198 | 70210 | 23017 | 29481102 |
Pain | 103.52 | 13.36 | 155 | 70253 | 171277 | 29332842 |
Rhabdomyolysis | 100.56 | 13.36 | 13 | 70395 | 60795 | 29443324 |
Muscle spasms | 100.51 | 13.36 | 17 | 70391 | 65065 | 29439054 |
Death | 100.22 | 13.36 | 447 | 69961 | 341637 | 29162482 |
Disease recurrence | 98.55 | 13.36 | 153 | 70255 | 15761 | 29488358 |
Hypogammaglobulinaemia | 96.79 | 13.36 | 93 | 70315 | 5814 | 29498305 |
Drug interaction | 96.20 | 13.36 | 204 | 70204 | 197181 | 29306938 |
Herpes simplex | 95.67 | 13.36 | 85 | 70323 | 4805 | 29499314 |
Neoplasm recurrence | 94.91 | 13.36 | 59 | 70349 | 1918 | 29502201 |
White blood cell count decreased | 92.92 | 13.36 | 419 | 69989 | 82943 | 29421176 |
Pruritus | 92.67 | 13.36 | 85 | 70323 | 116764 | 29387355 |
Sweat gland tumour | 91.10 | 13.36 | 35 | 70373 | 377 | 29503742 |
Anaemia | 90.47 | 13.36 | 800 | 69608 | 200151 | 29303968 |
Somnolence | 90.33 | 13.36 | 56 | 70352 | 93899 | 29410220 |
Weight increased | 89.87 | 13.36 | 35 | 70373 | 76632 | 29427487 |
Blood pressure increased | 89.35 | 13.36 | 32 | 70376 | 73771 | 29430348 |
Lymphopenia | 89.28 | 13.36 | 134 | 70274 | 13399 | 29490720 |
Joint swelling | 88.70 | 13.36 | 8 | 70400 | 49622 | 29454497 |
Myalgia | 88.08 | 13.36 | 33 | 70375 | 73986 | 29430133 |
Drug resistance | 87.54 | 13.36 | 172 | 70236 | 21368 | 29482751 |
Peripheral swelling | 87.38 | 13.36 | 22 | 70386 | 63717 | 29440402 |
Feeling abnormal | 86.82 | 13.36 | 13 | 70395 | 54432 | 29449687 |
Fatigue | 86.23 | 13.36 | 425 | 69983 | 316396 | 29187723 |
Hepatic failure | 85.48 | 13.36 | 214 | 70194 | 31298 | 29472821 |
Insomnia | 85.19 | 13.36 | 53 | 70355 | 88708 | 29415411 |
Headache | 84.61 | 13.36 | 180 | 70228 | 173827 | 29330292 |
Overdose | 83.28 | 13.36 | 43 | 70365 | 79776 | 29424343 |
Depression | 81.50 | 13.36 | 51 | 70357 | 85096 | 29419023 |
Tremor | 80.70 | 13.36 | 37 | 70371 | 73501 | 29430618 |
Venoocclusive liver disease | 79.37 | 13.36 | 90 | 70318 | 6827 | 29497292 |
Product use issue | 79.22 | 13.36 | 286 | 70122 | 51158 | 29452961 |
Epstein-Barr virus infection | 79.05 | 13.36 | 88 | 70320 | 6541 | 29497578 |
Pain in extremity | 78.81 | 13.36 | 88 | 70320 | 110345 | 29393774 |
Dyspnoea | 78.53 | 13.36 | 457 | 69951 | 326275 | 29177844 |
Malaise | 77.66 | 13.36 | 165 | 70243 | 159437 | 29344682 |
Drug hypersensitivity | 77.30 | 13.36 | 33 | 70375 | 68373 | 29435746 |
Blood glucose increased | 75.91 | 13.36 | 23 | 70385 | 58961 | 29445158 |
Azoospermia | 74.10 | 13.36 | 30 | 70378 | 375 | 29503744 |
Confusional state | 73.90 | 13.36 | 119 | 70289 | 127758 | 29376361 |
End stage renal disease | 73.51 | 13.36 | 91 | 70317 | 7573 | 29496546 |
Left ventricular dysfunction | 73.30 | 13.36 | 98 | 70310 | 8804 | 29495315 |
Aspergillus infection | 73 | 13.36 | 107 | 70301 | 10474 | 29493645 |
Cytokine release syndrome | 71.47 | 13.36 | 119 | 70289 | 13000 | 29491119 |
Anaplastic lymphoma kinase gene mutation | 69.88 | 13.36 | 21 | 70387 | 97 | 29504022 |
Cerebrovascular accident | 69.64 | 13.36 | 49 | 70359 | 76862 | 29427257 |
Intentional product misuse | 69.62 | 13.36 | 3 | 70405 | 34658 | 29469461 |
Candida infection | 68.54 | 13.36 | 127 | 70281 | 15098 | 29489021 |
Stomatitis | 67.36 | 13.36 | 218 | 70190 | 36895 | 29467224 |
Viral haemorrhagic cystitis | 66.25 | 13.36 | 36 | 70372 | 904 | 29503215 |
Myelopathy | 65.94 | 13.36 | 47 | 70361 | 1927 | 29502192 |
Aggression | 65.51 | 13.36 | 5 | 70403 | 35536 | 29468583 |
Pneumonitis | 65.38 | 13.36 | 180 | 70228 | 27864 | 29476255 |
Hospitalisation | 64.73 | 13.36 | 15 | 70393 | 45973 | 29458146 |
Neurotoxicity | 64.67 | 13.36 | 121 | 70287 | 14492 | 29489627 |
Blood creatine phosphokinase increased | 64.12 | 13.36 | 10 | 70398 | 40634 | 29463485 |
Haemophagocytic lymphohistiocytosis | 63.65 | 13.36 | 100 | 70308 | 10404 | 29493715 |
Bradycardia | 63.21 | 13.36 | 39 | 70369 | 65590 | 29438529 |
Peripheral sensory neuropathy | 62.64 | 13.36 | 74 | 70334 | 5865 | 29498254 |
Suicide attempt | 62.31 | 13.36 | 5 | 70403 | 34105 | 29470014 |
Chest pain | 61.17 | 13.36 | 108 | 70300 | 111865 | 29392254 |
Osteonecrosis | 61.15 | 13.36 | 113 | 70295 | 13406 | 29490713 |
Coronary artery disease | 61.04 | 13.36 | 15 | 70393 | 44175 | 29459944 |
Rheumatoid arthritis | 60.78 | 13.36 | 4 | 70404 | 32148 | 29471971 |
Post transplant lymphoproliferative disorder | 60.53 | 13.36 | 70 | 70338 | 5423 | 29498696 |
Venoocclusive disease | 59.60 | 13.36 | 49 | 70359 | 2490 | 29501629 |
Hallucination | 58.32 | 13.36 | 17 | 70391 | 44695 | 29459424 |
Musculoskeletal stiffness | 57.34 | 13.36 | 10 | 70398 | 37448 | 29466671 |
Traumatic lung injury | 56.10 | 13.36 | 35 | 70373 | 1145 | 29502974 |
Hypoglycaemia | 55.12 | 13.36 | 23 | 70385 | 48323 | 29455796 |
Inappropriate schedule of product administration | 54.29 | 13.36 | 19 | 70389 | 44453 | 29459666 |
JC virus infection | 53.97 | 13.36 | 41 | 70367 | 1856 | 29502263 |
Multiple organ dysfunction syndrome | 53.74 | 13.36 | 294 | 70114 | 62822 | 29441297 |
Escherichia sepsis | 53.35 | 13.36 | 56 | 70352 | 3893 | 29500226 |
Salivary gland cancer | 52.86 | 13.36 | 21 | 70387 | 249 | 29503870 |
Cystitis haemorrhagic | 52.18 | 13.36 | 61 | 70347 | 4781 | 29499338 |
Central nervous system lymphoma | 51.43 | 13.36 | 28 | 70380 | 706 | 29503413 |
Strongyloidiasis | 50.91 | 13.36 | 43 | 70365 | 2269 | 29501850 |
Malignant transformation | 50.75 | 13.36 | 29 | 70379 | 805 | 29503314 |
Bronchopulmonary aspergillosis | 50.66 | 13.36 | 99 | 70309 | 12245 | 29491874 |
Nasopharyngitis | 50.17 | 13.36 | 41 | 70367 | 59624 | 29444495 |
Chloroma | 49.93 | 13.36 | 24 | 70384 | 462 | 29503657 |
B-cell lymphoma refractory | 49.71 | 13.36 | 17 | 70391 | 127 | 29503992 |
Back pain | 49.48 | 13.36 | 106 | 70302 | 102178 | 29401941 |
Post embolisation syndrome | 48.40 | 13.36 | 14 | 70394 | 55 | 29504064 |
Pneumonia klebsiella | 47.86 | 13.36 | 44 | 70364 | 2600 | 29501519 |
Chronic obstructive pulmonary disease | 47.47 | 13.36 | 19 | 70389 | 40936 | 29463183 |
Refractory cancer | 46.62 | 13.36 | 16 | 70392 | 121 | 29503998 |
Intestinal perforation | 46.27 | 13.36 | 75 | 70333 | 8011 | 29496108 |
Acute lymphocytic leukaemia | 46.11 | 13.36 | 43 | 70365 | 2588 | 29501531 |
Contusion | 46.09 | 13.36 | 9 | 70399 | 31086 | 29473033 |
Neutropenic colitis | 45.36 | 13.36 | 41 | 70367 | 2370 | 29501749 |
Gene mutation | 44.82 | 13.36 | 29 | 70379 | 1012 | 29503107 |
Cardio-respiratory arrest | 44.79 | 13.36 | 33 | 70375 | 50568 | 29453551 |
Escherichia infection | 44.64 | 13.36 | 67 | 70341 | 6697 | 29497422 |
Hyperhidrosis | 44.31 | 13.36 | 53 | 70355 | 64487 | 29439632 |
Incorrect dose administered | 44.01 | 13.36 | 12 | 70396 | 32972 | 29471147 |
Infection | 43.87 | 13.36 | 323 | 70085 | 76428 | 29427691 |
Nephropathy toxic | 43.82 | 13.36 | 86 | 70322 | 10670 | 29493449 |
Memory impairment | 43.80 | 13.36 | 16 | 70392 | 36454 | 29467665 |
Gastritis bacterial | 43.77 | 13.36 | 17 | 70391 | 189 | 29503930 |
Infection reactivation | 43.67 | 13.36 | 29 | 70379 | 1058 | 29503061 |
Fungal infection | 43.64 | 13.36 | 99 | 70309 | 13586 | 29490533 |
Agitation | 43.45 | 13.36 | 35 | 70373 | 51269 | 29452850 |
Abnormal behaviour | 43.35 | 13.36 | 3 | 70405 | 23124 | 29480995 |
Interstitial lung disease | 43.32 | 13.36 | 260 | 70148 | 57458 | 29446661 |
Administration site extravasation | 43.28 | 13.36 | 22 | 70386 | 480 | 29503639 |
Lymphoma transformation | 43.06 | 13.36 | 16 | 70392 | 156 | 29503963 |
Injection site pain | 42.93 | 13.36 | 12 | 70396 | 32434 | 29471685 |
Wheezing | 42.69 | 13.36 | 13 | 70395 | 33227 | 29470892 |
Psoriasis | 42.49 | 13.36 | 12 | 70396 | 32215 | 29471904 |
Oedema peripheral | 42.45 | 13.36 | 117 | 70291 | 103440 | 29400679 |
Lung infiltration | 41.86 | 13.36 | 89 | 70319 | 11690 | 29492429 |
Gait disturbance | 41.63 | 13.36 | 69 | 70339 | 73280 | 29430839 |
Abdominal discomfort | 41.42 | 13.36 | 32 | 70376 | 47871 | 29456248 |
Sleep disorder | 40.82 | 13.36 | 5 | 70403 | 24381 | 29479738 |
Loss of consciousness | 40.81 | 13.36 | 71 | 70337 | 73985 | 29430134 |
Congenital cardiovascular anomaly | 40.79 | 13.36 | 16 | 70392 | 183 | 29503936 |
Cytogenetic abnormality | 40.73 | 13.36 | 25 | 70383 | 794 | 29503325 |
Loss of personal independence in daily activities | 40.71 | 13.36 | 6 | 70402 | 25434 | 29478685 |
Nephrolithiasis | 40.49 | 13.36 | 6 | 70402 | 25328 | 29478791 |
Asthma | 40.40 | 13.36 | 15 | 70393 | 33834 | 29470285 |
Peripheral T-cell lymphoma unspecified | 40.25 | 13.36 | 20 | 70388 | 415 | 29503704 |
Aplasia | 40.19 | 13.36 | 49 | 70359 | 4014 | 29500105 |
Colitis | 40.09 | 13.36 | 164 | 70244 | 31084 | 29473035 |
Heart rate decreased | 39.58 | 13.36 | 6 | 70402 | 24906 | 29479213 |
Autoimmune neutropenia | 39.02 | 13.36 | 17 | 70391 | 258 | 29503861 |
Urticaria | 38.47 | 13.36 | 44 | 70364 | 54616 | 29449503 |
Blood stem cell transplant failure | 38.04 | 13.36 | 19 | 70389 | 399 | 29503720 |
Diarrhoea | 37.94 | 13.36 | 561 | 69847 | 332137 | 29171982 |
Unevaluable event | 37.75 | 13.36 | 12 | 70396 | 29839 | 29474280 |
BK virus infection | 37.50 | 13.36 | 51 | 70357 | 4656 | 29499463 |
Staphylococcal sepsis | 37.50 | 13.36 | 72 | 70336 | 8790 | 29495329 |
Platelet count decreased | 36.31 | 13.36 | 395 | 70013 | 104277 | 29399842 |
Retinal haemorrhage | 36.19 | 13.36 | 49 | 70359 | 4455 | 29499664 |
Endocarditis noninfective | 36.10 | 13.36 | 13 | 70395 | 115 | 29504004 |
Agranulocytosis | 35.56 | 13.36 | 118 | 70290 | 20222 | 29483897 |
Osteosarcoma recurrent | 34.90 | 13.36 | 9 | 70399 | 20 | 29504099 |
Arthropathy | 34.69 | 13.36 | 5 | 70403 | 21549 | 29482570 |
Congestive cardiomyopathy | 34.59 | 13.36 | 59 | 70349 | 6571 | 29497548 |
Bacteraemia | 34.36 | 13.36 | 101 | 70307 | 16222 | 29487897 |
Injury | 34.21 | 13.36 | 3 | 70405 | 19043 | 29485076 |
Balance disorder | 34.12 | 13.36 | 22 | 70386 | 36148 | 29467971 |
Transformation to acute myeloid leukaemia | 34.02 | 13.36 | 21 | 70387 | 674 | 29503445 |
Chronic myeloid leukaemia | 33.82 | 13.36 | 32 | 70376 | 1962 | 29502157 |
Therapy non-responder | 33.36 | 13.36 | 154 | 70254 | 30757 | 29473362 |
Device related thrombosis | 33.10 | 13.36 | 23 | 70385 | 905 | 29503214 |
Ganglioneuroblastoma | 32.97 | 13.36 | 9 | 70399 | 27 | 29504092 |
Pseudomonas infection | 32.94 | 13.36 | 77 | 70331 | 10775 | 29493344 |
Autoimmune lymphoproliferative syndrome | 32.81 | 13.36 | 13 | 70395 | 153 | 29503966 |
Haemoglobin abnormal | 32.70 | 13.36 | 39 | 70369 | 3122 | 29500997 |
Syncope | 32.55 | 13.36 | 93 | 70315 | 81278 | 29422841 |
Cardiac failure congestive | 32.52 | 13.36 | 85 | 70323 | 76496 | 29427623 |
Cytomegalovirus infection reactivation | 32.35 | 13.36 | 40 | 70368 | 3324 | 29500795 |
Epstein-Barr virus associated lymphoma | 32.20 | 13.36 | 19 | 70389 | 561 | 29503558 |
Angioedema | 32.08 | 13.36 | 18 | 70390 | 31897 | 29472222 |
Hyperkalaemia | 31.91 | 13.36 | 61 | 70347 | 61331 | 29442788 |
Hepatic fibrosis | 31.81 | 13.36 | 39 | 70369 | 3213 | 29500906 |
Mobility decreased | 31.48 | 13.36 | 11 | 70397 | 25769 | 29478350 |
Subdural hygroma | 31.43 | 13.36 | 15 | 70393 | 284 | 29503835 |
Glioma | 31.34 | 13.36 | 15 | 70393 | 286 | 29503833 |
Cardiac arrest | 31.26 | 13.36 | 102 | 70306 | 85489 | 29418630 |
Lymphoma | 31.23 | 13.36 | 71 | 70337 | 9757 | 29494362 |
Heart rate increased | 31.21 | 13.36 | 28 | 70380 | 38910 | 29465209 |
Acute lymphocytic leukaemia recurrent | 31.03 | 13.36 | 34 | 70374 | 2482 | 29501637 |
International normalised ratio increased | 30.92 | 13.36 | 36 | 70372 | 44336 | 29459783 |
Vision blurred | 30.89 | 13.36 | 30 | 70378 | 40146 | 29463973 |
5q minus syndrome | 30.77 | 13.36 | 12 | 70396 | 135 | 29503984 |
Pneumothorax spontaneous | 30.71 | 13.36 | 16 | 70392 | 368 | 29503751 |
Respiratory failure | 30.71 | 13.36 | 360 | 70048 | 96771 | 29407348 |
Peripheral motor neuropathy | 30.71 | 13.36 | 28 | 70380 | 1637 | 29502482 |
Recurrent cancer | 30.57 | 13.36 | 24 | 70384 | 1141 | 29502978 |
Mass | 30.36 | 13.36 | 58 | 70350 | 7053 | 29497066 |
Hepatosplenic candidiasis | 30.28 | 13.36 | 13 | 70395 | 190 | 29503929 |
Chest discomfort | 30.26 | 13.36 | 39 | 70369 | 45944 | 29458175 |
Gastrointestinal toxicity | 30.19 | 13.36 | 31 | 70377 | 2100 | 29502019 |
Toxic erythema of chemotherapy | 30.05 | 13.36 | 10 | 70398 | 68 | 29504051 |
Pneumonia | 29.62 | 13.36 | 983 | 69425 | 319189 | 29184930 |
Device related infection | 29.40 | 13.36 | 93 | 70315 | 15543 | 29488576 |
Viral load increased | 29.38 | 13.36 | 30 | 70378 | 2019 | 29502100 |
Drug withdrawal syndrome | 29.34 | 13.36 | 4 | 70404 | 17980 | 29486139 |
Haematochezia | 29.16 | 13.36 | 27 | 70381 | 36956 | 29467163 |
Klebsiella infection | 29.02 | 13.36 | 58 | 70350 | 7291 | 29496828 |
Blood HIV RNA increased | 28.84 | 13.36 | 22 | 70386 | 1002 | 29503117 |
Cardiomyopathy acute | 28.83 | 13.36 | 8 | 70400 | 26 | 29504093 |
Metastases to lung | 28.66 | 13.36 | 60 | 70348 | 7795 | 29496324 |
Renal tubular disorder | 28.57 | 13.36 | 43 | 70365 | 4309 | 29499810 |
Splenic lesion | 28.26 | 13.36 | 11 | 70397 | 123 | 29503996 |
Drug clearance decreased | 28.25 | 13.36 | 25 | 70383 | 1405 | 29502714 |
Herpes simplex encephalitis | 28.16 | 13.36 | 14 | 70394 | 291 | 29503828 |
Metastases to spleen | 28.03 | 13.36 | 15 | 70393 | 365 | 29503754 |
Abdominal pain upper | 28.01 | 13.36 | 65 | 70343 | 60928 | 29443191 |
Gastric perforation | 27.76 | 13.36 | 30 | 70378 | 2156 | 29501963 |
Tidal volume decreased | 27.54 | 13.36 | 8 | 70400 | 32 | 29504087 |
Skin toxicity | 27.27 | 13.36 | 39 | 70369 | 3732 | 29500387 |
Mucosal toxicity | 27.26 | 13.36 | 12 | 70396 | 187 | 29503932 |
Pneumonia fungal | 27.02 | 13.36 | 49 | 70359 | 5728 | 29498391 |
Primitive neuroectodermal tumour | 26.94 | 13.36 | 9 | 70399 | 62 | 29504057 |
Toxicity to various agents | 26.86 | 13.36 | 274 | 70134 | 173387 | 29330732 |
Respiratory arrest | 26.80 | 13.36 | 14 | 70394 | 25819 | 29478300 |
Blood cholesterol increased | 26.59 | 13.36 | 3 | 70405 | 15592 | 29488527 |
Encephalitis enteroviral | 26.58 | 13.36 | 11 | 70397 | 146 | 29503973 |
Road traffic accident | 26.51 | 13.36 | 3 | 70405 | 15558 | 29488561 |
Disorientation | 26.44 | 13.36 | 19 | 70389 | 29496 | 29474623 |
Ototoxicity | 26.32 | 13.36 | 25 | 70383 | 1540 | 29502579 |
Accidental overdose | 26.27 | 13.36 | 5 | 70403 | 17588 | 29486531 |
Ill-defined disorder | 26.26 | 13.36 | 74 | 70334 | 11604 | 29492515 |
Pulmonary toxicity | 26.15 | 13.36 | 44 | 70364 | 4846 | 29499273 |
Secondary immunodeficiency | 26.15 | 13.36 | 14 | 70394 | 341 | 29503778 |
Gastrooesophageal reflux disease | 26.03 | 13.36 | 22 | 70386 | 31474 | 29472645 |
Hypertriglyceridaemia | 26.00 | 13.36 | 56 | 70352 | 7419 | 29496700 |
Haemorrhage | 25.94 | 13.36 | 42 | 70366 | 45030 | 29459089 |
Plasmacytoma | 25.86 | 13.36 | 35 | 70373 | 3180 | 29500939 |
Hypertension | 25.83 | 13.36 | 167 | 70241 | 116447 | 29387672 |
Intestinal atresia | 25.78 | 13.36 | 9 | 70399 | 72 | 29504047 |
Metastases to retroperitoneum | 25.75 | 13.36 | 12 | 70396 | 215 | 29503904 |
Myelitis transverse | 25.58 | 13.36 | 20 | 70388 | 945 | 29503174 |
West Nile viral infection | 25.29 | 13.36 | 17 | 70391 | 633 | 29503486 |
Chylothorax | 25.22 | 13.36 | 17 | 70391 | 636 | 29503483 |
Biliary-bronchial fistula | 25.21 | 13.36 | 5 | 70403 | 0 | 29504119 |
Cardiac dysfunction | 25.08 | 13.36 | 26 | 70382 | 1781 | 29502338 |
Peripheral sensorimotor neuropathy | 25.06 | 13.36 | 23 | 70385 | 1356 | 29502763 |
Gastrointestinal haemorrhage | 24.93 | 13.36 | 101 | 70307 | 79432 | 29424687 |
Product quality issue | 24.86 | 13.36 | 4 | 70404 | 15891 | 29488228 |
Hepatic infection fungal | 24.73 | 13.36 | 11 | 70397 | 176 | 29503943 |
Refractory anaemia with an excess of blasts | 24.68 | 13.36 | 14 | 70394 | 383 | 29503736 |
Cardiac failure | 24.67 | 13.36 | 293 | 70115 | 78994 | 29425125 |
Cerebral toxoplasmosis | 24.54 | 13.36 | 23 | 70385 | 1393 | 29502726 |
Irritability | 24.51 | 13.36 | 11 | 70397 | 22141 | 29481978 |
Mucormycosis | 24.44 | 13.36 | 44 | 70364 | 5114 | 29499005 |
Cellulitis gangrenous | 24.39 | 13.36 | 11 | 70397 | 182 | 29503937 |
Psychotic disorder | 24.32 | 13.36 | 9 | 70399 | 20345 | 29483774 |
Pleural effusion | 24.28 | 13.36 | 270 | 70138 | 71638 | 29432481 |
Testicular disorder | 24.28 | 13.36 | 16 | 70392 | 576 | 29503543 |
Cardiac disorder | 24.11 | 13.36 | 32 | 70376 | 37231 | 29466888 |
Depressed mood | 23.88 | 13.36 | 5 | 70403 | 16443 | 29487676 |
Osteosarcoma | 23.86 | 13.36 | 11 | 70397 | 192 | 29503927 |
Molluscum contagiosum | 23.81 | 13.36 | 12 | 70396 | 257 | 29503862 |
Hypersensitivity | 23.79 | 13.36 | 57 | 70351 | 52846 | 29451273 |
Blood pressure decreased | 23.79 | 13.36 | 45 | 70363 | 45432 | 29458687 |
Weight decreased | 23.78 | 13.36 | 237 | 70171 | 150668 | 29353451 |
Acute lymphocytic leukaemia refractory | 23.67 | 13.36 | 9 | 70399 | 94 | 29504025 |
Meningitis cryptococcal | 23.54 | 13.36 | 27 | 70381 | 2073 | 29502046 |
Meningitis tuberculous | 23.49 | 13.36 | 16 | 70392 | 609 | 29503510 |
Pulmonary sarcoidosis | 23.47 | 13.36 | 15 | 70393 | 512 | 29503607 |
Neurofibrosarcoma | 23.35 | 13.36 | 7 | 70401 | 32 | 29504087 |
Head injury | 23.11 | 13.36 | 5 | 70403 | 16076 | 29488043 |
Metastases to muscle | 22.97 | 13.36 | 11 | 70397 | 210 | 29503909 |
Escherichia bacteraemia | 22.82 | 13.36 | 31 | 70377 | 2827 | 29501292 |
Unresponsive to stimuli | 22.73 | 13.36 | 16 | 70392 | 25110 | 29479009 |
Palmar-plantar erythrodysaesthesia syndrome | 22.65 | 13.36 | 82 | 70326 | 14677 | 29489442 |
Drug reaction with eosinophilia and systemic symptoms | 22.58 | 13.36 | 20 | 70388 | 27972 | 29476147 |
Lentigo | 22.52 | 13.36 | 13 | 70395 | 368 | 29503751 |
Morphoea | 22.48 | 13.36 | 10 | 70398 | 160 | 29503959 |
Infusion site discolouration | 22.41 | 13.36 | 9 | 70399 | 110 | 29504009 |
Glioblastoma multiforme | 22.34 | 13.36 | 16 | 70392 | 661 | 29503458 |
Enterovirus infection | 22.34 | 13.36 | 16 | 70392 | 661 | 29503458 |
Haematopoietic stem cell mobilisation | 22.31 | 13.36 | 10 | 70398 | 163 | 29503956 |
Pneumocystis jirovecii infection | 22.23 | 13.36 | 22 | 70386 | 1426 | 29502693 |
Cutaneous T-cell lymphoma recurrent | 22.21 | 13.36 | 7 | 70401 | 39 | 29504080 |
Gait inability | 22.16 | 13.36 | 8 | 70400 | 18367 | 29485752 |
Transient ischaemic attack | 22.15 | 13.36 | 14 | 70394 | 23256 | 29480863 |
Adverse drug reaction | 22.12 | 13.36 | 15 | 70393 | 24005 | 29480114 |
COVID-19 pneumonia | 22.06 | 13.36 | 61 | 70347 | 9461 | 29494658 |
Stevens-Johnson syndrome | 22.01 | 13.36 | 6 | 70402 | 16491 | 29487628 |
Periorbital infection | 21.98 | 13.36 | 9 | 70399 | 116 | 29504003 |
Treatment failure | 21.97 | 13.36 | 157 | 70251 | 36782 | 29467337 |
Acute lung injury | 21.86 | 13.36 | 21 | 70387 | 1312 | 29502807 |
Faeces discoloured | 21.71 | 13.36 | 3 | 70405 | 13348 | 29490771 |
Bacterial infection | 21.64 | 13.36 | 74 | 70334 | 12874 | 29491245 |
Clostridium difficile colitis | 21.64 | 13.36 | 75 | 70333 | 13137 | 29490982 |
Phlebitis infective | 21.64 | 13.36 | 9 | 70399 | 121 | 29503998 |
Blood urea increased | 21.60 | 13.36 | 21 | 70387 | 28091 | 29476028 |
Intentional product use issue | 21.56 | 13.36 | 174 | 70234 | 42324 | 29461795 |
Positron emission tomogram abnormal | 21.38 | 13.36 | 9 | 70399 | 125 | 29503994 |
Sphingomonas paucimobilis infection | 21.37 | 13.36 | 7 | 70401 | 45 | 29504074 |
Fluid retention | 21.32 | 13.36 | 15 | 70393 | 23545 | 29480574 |
Spindle cell sarcoma | 21.31 | 13.36 | 9 | 70399 | 126 | 29503993 |
Oesophageal candidiasis | 21.26 | 13.36 | 35 | 70373 | 3786 | 29500333 |
Hepatitis viral | 21.22 | 13.36 | 14 | 70394 | 505 | 29503614 |
Streptococcal infection | 20.90 | 13.36 | 38 | 70370 | 4450 | 29499669 |
Blood pressure systolic increased | 20.89 | 13.36 | 7 | 70401 | 16838 | 29487281 |
Burning sensation | 20.89 | 13.36 | 6 | 70402 | 15932 | 29488187 |
Dry skin | 20.88 | 13.36 | 15 | 70393 | 23292 | 29480827 |
Suspected product quality issue | 20.81 | 13.36 | 9 | 70399 | 134 | 29503985 |
Injection site erythema | 20.76 | 13.36 | 4 | 70404 | 13952 | 29490167 |
Disorder of orbit | 20.75 | 13.36 | 8 | 70400 | 87 | 29504032 |
Salivary gland neoplasm | 20.66 | 13.36 | 6 | 70402 | 24 | 29504095 |
Cancer fatigue | 20.62 | 13.36 | 7 | 70401 | 51 | 29504068 |
Oxygen saturation decreased | 20.54 | 13.36 | 48 | 70360 | 44889 | 29459230 |
Disseminated cytomegaloviral infection | 20.50 | 13.36 | 10 | 70398 | 199 | 29503920 |
Taeniasis | 20.50 | 13.36 | 7 | 70401 | 52 | 29504067 |
Herpes zoster | 20.42 | 13.36 | 132 | 70276 | 29920 | 29474199 |
Scedosporium infection | 20.23 | 13.36 | 16 | 70392 | 769 | 29503350 |
Restlessness | 20.17 | 13.36 | 14 | 70394 | 22131 | 29481988 |
Clostridium difficile infection | 20.14 | 13.36 | 84 | 70324 | 16057 | 29488062 |
Splenic marginal zone lymphoma | 20.09 | 13.36 | 6 | 70402 | 27 | 29504092 |
Acute pulmonary histoplasmosis | 19.95 | 13.36 | 9 | 70399 | 149 | 29503970 |
Treatment noncompliance | 19.92 | 13.36 | 17 | 70391 | 24210 | 29479909 |
Sarcoma metastatic | 19.84 | 13.36 | 7 | 70401 | 58 | 29504061 |
Mucoepidermoid carcinoma of salivary gland | 19.75 | 13.36 | 5 | 70403 | 10 | 29504109 |
Marginal zone lymphoma recurrent | 19.74 | 13.36 | 6 | 70402 | 29 | 29504090 |
Metastases to bone marrow | 19.70 | 13.36 | 13 | 70395 | 469 | 29503650 |
Pulmonary embolism | 19.65 | 13.36 | 273 | 70135 | 76261 | 29427858 |
Extravasation | 19.60 | 13.36 | 22 | 70386 | 1650 | 29502469 |
Electrocardiogram QT prolonged | 19.57 | 13.36 | 35 | 70373 | 36102 | 29468017 |
Plasmablastic lymphoma | 19.56 | 13.36 | 10 | 70398 | 221 | 29503898 |
Candida endophthalmitis | 19.55 | 13.36 | 8 | 70400 | 103 | 29504016 |
Hepatic amoebiasis | 19.53 | 13.36 | 7 | 70401 | 61 | 29504058 |
Hepatitis B DNA increased | 19.32 | 13.36 | 13 | 70395 | 485 | 29503634 |
Wrong technique in product usage process | 19.32 | 13.36 | 28 | 70380 | 31400 | 29472719 |
Adenocarcinoma gastric | 19.28 | 13.36 | 18 | 70390 | 1085 | 29503034 |
Swelling | 19.27 | 13.36 | 34 | 70374 | 35249 | 29468870 |
Rash pruritic | 19.25 | 13.36 | 15 | 70393 | 22348 | 29481771 |
Bone marrow disorder | 19.19 | 13.36 | 21 | 70387 | 1531 | 29502588 |
Hepatitis | 19.16 | 13.36 | 99 | 70309 | 20684 | 29483435 |
Labelled drug-drug interaction medication error | 19.15 | 13.36 | 3 | 70405 | 12156 | 29491963 |
Sleep apnoea syndrome | 19.06 | 13.36 | 9 | 70399 | 17590 | 29486529 |
Toxic cardiomyopathy | 18.92 | 13.36 | 10 | 70398 | 237 | 29503882 |
Ileus | 18.79 | 13.36 | 76 | 70332 | 14326 | 29489793 |
Nausea | 18.75 | 13.36 | 535 | 69873 | 288720 | 29215399 |
Gastric stenosis | 18.67 | 13.36 | 6 | 70402 | 36 | 29504083 |
Flushing | 18.65 | 13.36 | 25 | 70383 | 28967 | 29475152 |
Laboratory test abnormal | 18.65 | 13.36 | 10 | 70398 | 18175 | 29485944 |
Hypoaesthesia | 18.63 | 13.36 | 65 | 70343 | 53402 | 29450717 |
Splenic candidiasis | 18.42 | 13.36 | 7 | 70401 | 73 | 29504046 |
Swelling face | 18.35 | 13.36 | 13 | 70395 | 20337 | 29483782 |
Superior vena cava syndrome | 18.34 | 13.36 | 13 | 70395 | 528 | 29503591 |
Surgery | 18.34 | 13.36 | 3 | 70405 | 11776 | 29492343 |
Systemic mycosis | 18.32 | 13.36 | 19 | 70389 | 1302 | 29502817 |
Venous thrombosis | 18.20 | 13.36 | 29 | 70379 | 3053 | 29501066 |
Scleroderma | 18.12 | 13.36 | 19 | 70389 | 1319 | 29502800 |
Blood lactate dehydrogenase increased | 18.06 | 13.36 | 92 | 70316 | 19117 | 29485002 |
Premature ageing | 17.85 | 13.36 | 7 | 70401 | 80 | 29504039 |
Abdominal neoplasm | 17.80 | 13.36 | 9 | 70399 | 194 | 29503925 |
Diabetic ketoacidosis | 17.75 | 13.36 | 8 | 70400 | 16065 | 29488054 |
Immunosuppression | 17.70 | 13.36 | 39 | 70369 | 5247 | 29498872 |
Chronic lymphocytic leukaemia refractory | 17.70 | 13.36 | 7 | 70401 | 82 | 29504037 |
Chromosome analysis abnormal | 17.65 | 13.36 | 8 | 70400 | 134 | 29503985 |
Total lung capacity decreased | 17.61 | 13.36 | 13 | 70395 | 563 | 29503556 |
B precursor type acute leukaemia | 17.60 | 13.36 | 8 | 70400 | 135 | 29503984 |
B-cell type acute leukaemia | 17.58 | 13.36 | 10 | 70398 | 275 | 29503844 |
Nightmare | 17.57 | 13.36 | 3 | 70405 | 11414 | 29492705 |
Lip swelling | 17.55 | 13.36 | 4 | 70404 | 12406 | 29491713 |
Cryptococcal fungaemia | 17.40 | 13.36 | 7 | 70401 | 86 | 29504033 |
Seizure | 17.39 | 13.36 | 140 | 70268 | 92983 | 29411136 |
Dysgeusia | 17.35 | 13.36 | 17 | 70391 | 22657 | 29481462 |
Amnesia | 17.30 | 13.36 | 17 | 70391 | 22626 | 29481493 |
Helicobacter sepsis | 17.21 | 13.36 | 5 | 70403 | 20 | 29504099 |
Facial paresis | 17.20 | 13.36 | 26 | 70382 | 2615 | 29501504 |
IIIrd nerve paresis | 17.18 | 13.36 | 7 | 70401 | 89 | 29504030 |
Acute hepatic failure | 17.16 | 13.36 | 65 | 70343 | 11887 | 29492232 |
Plasma cell myeloma refractory | 17.11 | 13.36 | 7 | 70401 | 90 | 29504029 |
Injection site reaction | 17.09 | 13.36 | 3 | 70405 | 11185 | 29492934 |
Pneumonia salmonella | 17.08 | 13.36 | 6 | 70402 | 49 | 29504070 |
Hot flush | 17.06 | 13.36 | 7 | 70401 | 14863 | 29489256 |
Rhabdomyosarcoma recurrent | 17.04 | 13.36 | 7 | 70401 | 91 | 29504028 |
Fanconi syndrome | 17.00 | 13.36 | 20 | 70388 | 1578 | 29502541 |
Focal nodular hyperplasia | 16.98 | 13.36 | 8 | 70400 | 147 | 29503972 |
Abdominal wound dehiscence | 16.91 | 13.36 | 7 | 70401 | 93 | 29504026 |
Fusarium infection | 16.91 | 13.36 | 16 | 70392 | 981 | 29503138 |
Postural tremor | 16.86 | 13.36 | 10 | 70398 | 298 | 29503821 |
Granulocytopenia neonatal | 16.83 | 13.36 | 5 | 70403 | 22 | 29504097 |
Visual impairment | 16.79 | 13.36 | 28 | 70380 | 29680 | 29474439 |
Cholelithiasis | 16.75 | 13.36 | 12 | 70396 | 18660 | 29485459 |
Eczema | 16.71 | 13.36 | 6 | 70402 | 13820 | 29490299 |
Small intestinal perforation | 16.66 | 13.36 | 20 | 70388 | 1612 | 29502507 |
Lactic acidosis | 16.65 | 13.36 | 29 | 70379 | 30218 | 29473901 |
Ichthyosis | 16.64 | 13.36 | 7 | 70401 | 97 | 29504022 |
Liver function test abnormal | 16.59 | 13.36 | 27 | 70381 | 28891 | 29475228 |
Guillain-Barre syndrome | 16.58 | 13.36 | 37 | 70371 | 5021 | 29499098 |
Disturbance in attention | 16.46 | 13.36 | 16 | 70392 | 21408 | 29482711 |
Wound evisceration | 16.45 | 13.36 | 7 | 70401 | 100 | 29504019 |
Disseminated cryptococcosis | 16.44 | 13.36 | 17 | 70391 | 1161 | 29502958 |
Resorption bone increased | 16.41 | 13.36 | 8 | 70400 | 159 | 29503960 |
Drug ineffective for unapproved indication | 16.21 | 13.36 | 72 | 70336 | 14142 | 29489977 |
Skin exfoliation | 16.18 | 13.36 | 18 | 70390 | 22627 | 29481492 |
Respiratory depression | 16.12 | 13.36 | 6 | 70402 | 13517 | 29490602 |
Benign prostatic hyperplasia | 16.12 | 13.36 | 4 | 70404 | 11706 | 29492413 |
Renal disorder | 16.10 | 13.36 | 18 | 70390 | 22577 | 29481542 |
Vertigo | 16.03 | 13.36 | 17 | 70391 | 21844 | 29482275 |
Mastitis | 16.01 | 13.36 | 8 | 70400 | 168 | 29503951 |
Combined immunodeficiency | 16.01 | 13.36 | 6 | 70402 | 60 | 29504059 |
Dementia | 16.01 | 13.36 | 4 | 70404 | 11654 | 29492465 |
Metastasis | 15.93 | 13.36 | 29 | 70379 | 3400 | 29500719 |
Plasma cell leukaemia | 15.88 | 13.36 | 14 | 70394 | 783 | 29503336 |
Therapy responder | 15.84 | 13.36 | 8 | 70400 | 172 | 29503947 |
Blindness cortical | 15.82 | 13.36 | 10 | 70398 | 335 | 29503784 |
Hallucination, visual | 15.78 | 13.36 | 8 | 70400 | 15007 | 29489112 |
Musculoskeletal pain | 15.72 | 13.36 | 28 | 70380 | 28925 | 29475194 |
Hepatotoxicity | 15.71 | 13.36 | 84 | 70324 | 17783 | 29486336 |
Adrenocortical carcinoma | 15.70 | 13.36 | 5 | 70403 | 29 | 29504090 |
Congenital hepatobiliary anomaly | 15.70 | 13.36 | 5 | 70403 | 29 | 29504090 |
Depressed level of consciousness | 15.67 | 13.36 | 41 | 70367 | 36901 | 29467218 |
Blastic plasmacytoid dendritic cell neoplasia | 15.67 | 13.36 | 6 | 70402 | 64 | 29504055 |
Hip fracture | 15.62 | 13.36 | 3 | 70405 | 10489 | 29493630 |
Myeloid leukaemia | 15.58 | 13.36 | 10 | 70398 | 344 | 29503775 |
Leukonychia | 15.48 | 13.36 | 4 | 70404 | 9 | 29504110 |
Bone marrow infiltration | 15.46 | 13.36 | 7 | 70401 | 117 | 29504002 |
Neoplasm | 15.43 | 13.36 | 32 | 70376 | 4129 | 29499990 |
Lymphocytosis | 15.42 | 13.36 | 21 | 70387 | 1919 | 29502200 |
Neuroborreliosis | 15.42 | 13.36 | 5 | 70403 | 31 | 29504088 |
Mental status changes | 15.41 | 13.36 | 38 | 70370 | 34889 | 29469230 |
Dyskinesia | 15.40 | 13.36 | 15 | 70393 | 20046 | 29484073 |
Enterococcal infection | 15.38 | 13.36 | 49 | 70359 | 8219 | 29495900 |
Erythema | 15.37 | 13.36 | 111 | 70297 | 75495 | 29428624 |
Pneumonia mycoplasmal | 15.35 | 13.36 | 12 | 70396 | 567 | 29503552 |
Candida sepsis | 15.30 | 13.36 | 16 | 70392 | 1107 | 29503012 |
Heart disease congenital | 15.27 | 13.36 | 17 | 70391 | 1263 | 29502856 |
Influenza | 15.21 | 13.36 | 50 | 70358 | 41831 | 29462288 |
Leukoencephalopathy | 15.20 | 13.36 | 30 | 70378 | 3737 | 29500382 |
Diabetes mellitus inadequate control | 15.12 | 13.36 | 5 | 70403 | 12129 | 29491990 |
Delusion | 15.11 | 13.36 | 4 | 70404 | 11212 | 29492907 |
Pseudomonal sepsis | 15.11 | 13.36 | 26 | 70382 | 2916 | 29501203 |
Lewis-Sumner syndrome | 15.02 | 13.36 | 5 | 70403 | 34 | 29504085 |
Paternal exposure timing unspecified | 15.02 | 13.36 | 5 | 70403 | 34 | 29504085 |
Dehydration | 14.98 | 13.36 | 188 | 70220 | 114560 | 29389559 |
Hepatitis C RNA increased | 14.97 | 13.36 | 9 | 70399 | 275 | 29503844 |
Leukaemia | 14.96 | 13.36 | 30 | 70378 | 3780 | 29500339 |
Neuroblastoma recurrent | 14.89 | 13.36 | 6 | 70402 | 74 | 29504045 |
Influenza like illness | 14.84 | 13.36 | 22 | 70386 | 24448 | 29479671 |
Coronary artery occlusion | 14.79 | 13.36 | 3 | 70405 | 10091 | 29494028 |
Pneumaturia | 14.78 | 13.36 | 5 | 70403 | 36 | 29504083 |
Genotoxicity | 14.78 | 13.36 | 5 | 70403 | 36 | 29504083 |
Humoral immune defect | 14.75 | 13.36 | 6 | 70402 | 76 | 29504043 |
Chemotherapeutic drug level increased | 14.68 | 13.36 | 8 | 70400 | 202 | 29503917 |
Spinal cord ischaemia | 14.68 | 13.36 | 6 | 70402 | 77 | 29504042 |
Therapeutic product effect decreased | 14.66 | 13.36 | 30 | 70378 | 29421 | 29474698 |
Metapneumovirus bronchiolitis | 14.65 | 13.36 | 4 | 70404 | 12 | 29504107 |
Peripheral T-cell lymphoma unspecified refractory | 14.65 | 13.36 | 4 | 70404 | 12 | 29504107 |
Granulocyte count decreased | 14.56 | 13.36 | 12 | 70396 | 612 | 29503507 |
Acute hepatitis B | 14.55 | 13.36 | 7 | 70401 | 135 | 29503984 |
Asthenia | 14.46 | 13.36 | 396 | 70012 | 214854 | 29289265 |
Plasma cell myeloma recurrent | 14.46 | 13.36 | 29 | 70379 | 3654 | 29500465 |
Metastases to meninges | 14.37 | 13.36 | 16 | 70392 | 1189 | 29502930 |
Metabolic acidosis | 14.36 | 13.36 | 44 | 70364 | 37618 | 29466501 |
Extrapyramidal disorder | 14.34 | 13.36 | 4 | 70404 | 10827 | 29493292 |
Neck pain | 14.30 | 13.36 | 18 | 70390 | 21429 | 29482690 |
Hepatosplenomegaly | 14.28 | 13.36 | 29 | 70379 | 3688 | 29500431 |
Hypersomnia | 14.18 | 13.36 | 4 | 70404 | 10750 | 29493369 |
Oligohydramnios | 14.17 | 13.36 | 9 | 70399 | 304 | 29503815 |
Cytomegalovirus viraemia | 14.16 | 13.36 | 40 | 70368 | 6280 | 29497839 |
Neutrophil count increased | 14.13 | 13.36 | 71 | 70337 | 14671 | 29489448 |
Sudden death | 14.12 | 13.36 | 8 | 70400 | 14102 | 29490017 |
Cryptosporidiosis infection | 14.09 | 13.36 | 10 | 70398 | 407 | 29503712 |
Visual acuity reduced | 14.09 | 13.36 | 9 | 70399 | 14867 | 29489252 |
Hypercalcaemia | 14.08 | 13.36 | 64 | 70344 | 12695 | 29491424 |
Sinusitis bacterial | 14.06 | 13.36 | 9 | 70399 | 308 | 29503811 |
Exophthalmos | 14.05 | 13.36 | 11 | 70397 | 521 | 29503598 |
Optic ischaemic neuropathy | 14.05 | 13.36 | 20 | 70388 | 1906 | 29502213 |
Respiratory tract infection | 14.04 | 13.36 | 74 | 70334 | 15577 | 29488542 |
Stomatitis necrotising | 14.02 | 13.36 | 6 | 70402 | 87 | 29504032 |
VIth nerve paresis | 14.01 | 13.36 | 5 | 70403 | 43 | 29504076 |
Abdominal mass | 14.00 | 13.36 | 16 | 70392 | 1224 | 29502895 |
Embolism | 13.87 | 13.36 | 42 | 70366 | 6854 | 29497265 |
Central nervous system enteroviral infection | 13.81 | 13.36 | 5 | 70403 | 45 | 29504074 |
Blindness | 13.79 | 13.36 | 61 | 70347 | 11962 | 29492157 |
Coxsackie viral infection | 13.77 | 13.36 | 4 | 70404 | 16 | 29504103 |
Torulopsis infection | 13.77 | 13.36 | 4 | 70404 | 16 | 29504103 |
Coma | 13.72 | 13.36 | 48 | 70360 | 39402 | 29464717 |
Swollen tongue | 13.71 | 13.36 | 6 | 70402 | 12260 | 29491859 |
Haemoptysis | 13.66 | 13.36 | 33 | 70375 | 30517 | 29473602 |
Gingivitis ulcerative | 13.62 | 13.36 | 5 | 70403 | 47 | 29504072 |
Stem cell transplant | 13.57 | 13.36 | 20 | 70388 | 1967 | 29502152 |
Pneumonia respiratory syncytial viral | 13.55 | 13.36 | 13 | 70395 | 811 | 29503308 |
Systemic candida | 13.54 | 13.36 | 24 | 70384 | 2756 | 29501363 |
Chronic myelomonocytic leukaemia | 13.53 | 13.36 | 11 | 70397 | 550 | 29503569 |
Procedural pneumothorax | 13.52 | 13.36 | 5 | 70403 | 48 | 29504071 |
Human polyomavirus infection | 13.49 | 13.36 | 12 | 70396 | 679 | 29503440 |
Hip deformity | 13.49 | 13.36 | 6 | 70402 | 96 | 29504023 |
Cutaneous T-cell lymphoma | 13.45 | 13.36 | 16 | 70392 | 1277 | 29502842 |
Febrile infection | 13.44 | 13.36 | 20 | 70388 | 1984 | 29502135 |
Tuberculosis liver | 13.43 | 13.36 | 5 | 70403 | 49 | 29504070 |
Subclavian vein thrombosis | 13.40 | 13.36 | 13 | 70395 | 822 | 29503297 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Febrile neutropenia | 7040.98 | 12.06 | 4594 | 134312 | 183063 | 64176763 |
Neutropenia | 2884.95 | 12.06 | 3037 | 135869 | 236587 | 64123239 |
Acute myeloid leukaemia | 1378.86 | 12.06 | 813 | 138093 | 26650 | 64333176 |
Product use in unapproved indication | 1366.85 | 12.06 | 1788 | 137118 | 174830 | 64184996 |
Myelodysplastic syndrome | 1205.40 | 12.06 | 747 | 138159 | 26832 | 64332994 |
Mucosal inflammation | 1202.34 | 12.06 | 1030 | 137876 | 61554 | 64298272 |
Second primary malignancy | 1192.92 | 12.06 | 566 | 138340 | 11771 | 64348055 |
Haematotoxicity | 1166.02 | 12.06 | 565 | 138341 | 12331 | 64347495 |
Off label use | 1032.94 | 12.06 | 3342 | 135564 | 629464 | 63730362 |
Cardiotoxicity | 1007.55 | 12.06 | 476 | 138430 | 9798 | 64350028 |
Bone marrow failure | 914.22 | 12.06 | 786 | 138120 | 47166 | 64312660 |
Disease progression | 903.14 | 12.06 | 1307 | 137599 | 140373 | 64219453 |
Thrombocytopenia | 857.56 | 12.06 | 1642 | 137264 | 222159 | 64137667 |
Pancytopenia | 808.86 | 12.06 | 1249 | 137657 | 142060 | 64217766 |
Diffuse large B-cell lymphoma recurrent | 802.72 | 12.06 | 289 | 138617 | 2857 | 64356969 |
Hepatitis B | 702.07 | 12.06 | 340 | 138566 | 7405 | 64352421 |
Malignant neoplasm progression | 670.90 | 12.06 | 1008 | 137898 | 111863 | 64247963 |
Pneumocystis jirovecii pneumonia | 605.32 | 12.06 | 491 | 138415 | 27143 | 64332683 |
Febrile bone marrow aplasia | 598.44 | 12.06 | 346 | 138560 | 10909 | 64348917 |
Hepatitis B reactivation | 594.10 | 12.06 | 263 | 138643 | 4626 | 64355200 |
Myelosuppression | 585.44 | 12.06 | 453 | 138453 | 23377 | 64336449 |
Tumour lysis syndrome | 567.84 | 12.06 | 410 | 138496 | 19030 | 64340796 |
Cardiomyopathy | 560.60 | 12.06 | 453 | 138453 | 24903 | 64334923 |
Interstitial lung disease | 519.29 | 12.06 | 829 | 138077 | 96903 | 64262923 |
Neutropenic sepsis | 471.02 | 12.06 | 395 | 138511 | 22877 | 64336949 |
Ejection fraction decreased | 443.16 | 12.06 | 418 | 138488 | 28289 | 64331537 |
Fall | 438.44 | 12.06 | 175 | 138731 | 416651 | 63943175 |
Neoplasm progression | 416.79 | 12.06 | 477 | 138429 | 40487 | 64319339 |
Leukopenia | 413.10 | 12.06 | 764 | 138142 | 100478 | 64259348 |
Septic shock | 409.48 | 12.06 | 779 | 138127 | 104658 | 64255168 |
Joint swelling | 375.49 | 12.06 | 22 | 138884 | 215360 | 64144466 |
Pyrexia | 373.92 | 12.06 | 2263 | 136643 | 556381 | 63803445 |
Neuropathy peripheral | 373.68 | 12.06 | 799 | 138107 | 116726 | 64243100 |
Neutrophil count decreased | 368.34 | 12.06 | 624 | 138282 | 76572 | 64283254 |
Sepsis | 341.17 | 12.06 | 1181 | 137725 | 229160 | 64130666 |
Pain | 336.08 | 12.06 | 420 | 138486 | 553091 | 63806735 |
Therapy partial responder | 336.01 | 12.06 | 232 | 138674 | 10016 | 64349810 |
Rheumatoid arthritis | 323.80 | 12.06 | 6 | 138900 | 164288 | 64195538 |
Posterior reversible encephalopathy syndrome | 318.14 | 12.06 | 315 | 138591 | 22631 | 64337195 |
Anaemia | 318.10 | 12.06 | 1632 | 137274 | 377048 | 63982778 |
Arthralgia | 315.62 | 12.06 | 293 | 138613 | 441967 | 63917859 |
Palmar-plantar erythrodysaesthesia syndrome | 304.01 | 12.06 | 342 | 138564 | 28477 | 64331349 |
Cytopenia | 297.46 | 12.06 | 255 | 138651 | 15216 | 64344610 |
Product dose omission issue | 288.30 | 12.06 | 39 | 138867 | 194708 | 64165118 |
Peripheral swelling | 278.25 | 12.06 | 56 | 138850 | 209097 | 64150729 |
Acquired gene mutation | 267.86 | 12.06 | 115 | 138791 | 1871 | 64357955 |
Headache | 264.36 | 12.06 | 460 | 138446 | 529007 | 63830819 |
Left ventricular dysfunction | 263.79 | 12.06 | 248 | 138658 | 16706 | 64343120 |
Progressive multifocal leukoencephalopathy | 255.92 | 12.06 | 252 | 138654 | 17980 | 64341846 |
Diffuse large B-cell lymphoma refractory | 252.42 | 12.06 | 94 | 138812 | 1030 | 64358796 |
Dizziness | 248.87 | 12.06 | 338 | 138568 | 429825 | 63930001 |
Metastases to bone | 246.01 | 12.06 | 260 | 138646 | 20175 | 64339651 |
Drug hypersensitivity | 244.57 | 12.06 | 103 | 138803 | 237712 | 64122114 |
Weight increased | 241.90 | 12.06 | 79 | 138827 | 213269 | 64146557 |
Pruritus | 227.35 | 12.06 | 203 | 138703 | 312197 | 64047629 |
Drug abuse | 226.18 | 12.06 | 15 | 138891 | 132359 | 64227467 |
Disease recurrence | 218.43 | 12.06 | 303 | 138603 | 31207 | 64328619 |
Cardiac failure | 218.13 | 12.06 | 704 | 138202 | 131669 | 64228157 |
Abdominal discomfort | 216.61 | 12.06 | 62 | 138844 | 182260 | 64177566 |
Congestive cardiomyopathy | 210.14 | 12.06 | 176 | 138730 | 10168 | 64349658 |
Cytomegalovirus chorioretinitis | 209.28 | 12.06 | 131 | 138775 | 4781 | 64355045 |
Rash | 204.51 | 12.06 | 426 | 138480 | 458123 | 63901703 |
Nasopharyngitis | 201.42 | 12.06 | 85 | 138821 | 195988 | 64163838 |
B-cell lymphoma recurrent | 199.44 | 12.06 | 73 | 138833 | 759 | 64359067 |
Metastases to lung | 192.30 | 12.06 | 199 | 138707 | 15065 | 64344761 |
Musculoskeletal stiffness | 191.29 | 12.06 | 21 | 138885 | 123185 | 64236641 |
Synovitis | 189.79 | 12.06 | 5 | 138901 | 99085 | 64260741 |
Insomnia | 188.89 | 12.06 | 95 | 138811 | 197741 | 64162085 |
White blood cell count decreased | 187.24 | 12.06 | 754 | 138152 | 157083 | 64202743 |
Polyneuropathy | 181.26 | 12.06 | 219 | 138687 | 19675 | 64340151 |
Anxiety | 180.81 | 12.06 | 106 | 138800 | 202543 | 64157283 |
Multiple organ dysfunction syndrome | 179.55 | 12.06 | 553 | 138353 | 100860 | 64258966 |
Somnolence | 175.45 | 12.06 | 111 | 138795 | 203534 | 64156292 |
Lymphadenopathy | 174.99 | 12.06 | 340 | 138566 | 46346 | 64313480 |
Intentional overdose | 174.32 | 12.06 | 4 | 138902 | 89940 | 64269886 |
Arthropathy | 172.51 | 12.06 | 27 | 138879 | 120940 | 64238886 |
Blood pressure increased | 170.60 | 12.06 | 79 | 138827 | 172473 | 64187353 |
Acute promyelocytic leukaemia | 169.69 | 12.06 | 75 | 138831 | 1313 | 64358513 |
Overdose | 165.75 | 12.06 | 68 | 138838 | 159498 | 64200328 |
Muscle spasms | 163.74 | 12.06 | 50 | 138856 | 140973 | 64218853 |
Pain in extremity | 163.39 | 12.06 | 250 | 138656 | 302835 | 64056991 |
Haemophagocytic lymphohistiocytosis | 162.31 | 12.06 | 195 | 138711 | 17414 | 64342412 |
Swelling | 162.07 | 12.06 | 71 | 138835 | 160147 | 64199679 |
Neutropenic colitis | 160.35 | 12.06 | 108 | 138798 | 4473 | 64355353 |
Aplasia | 157.39 | 12.06 | 126 | 138780 | 6827 | 64352999 |
Injection site pain | 156.32 | 12.06 | 26 | 138880 | 111382 | 64248444 |
Feeling abnormal | 155.78 | 12.06 | 47 | 138859 | 133555 | 64226271 |
Metastases to liver | 153.77 | 12.06 | 222 | 138684 | 23719 | 64336107 |
Pneumonitis | 151.43 | 12.06 | 335 | 138571 | 50030 | 64309796 |
Platelet count decreased | 148.18 | 12.06 | 734 | 138172 | 166977 | 64192849 |
Contusion | 146.39 | 12.06 | 33 | 138873 | 113932 | 64245894 |
Peripheral sensory neuropathy | 144.52 | 12.06 | 149 | 138757 | 11229 | 64348597 |
Mantle cell lymphoma recurrent | 143.98 | 12.06 | 50 | 138856 | 440 | 64359386 |
Neurotoxicity | 143.34 | 12.06 | 231 | 138675 | 27173 | 64332653 |
Drug resistance | 141.87 | 12.06 | 264 | 138642 | 34838 | 64324988 |
Pleural effusion | 141.67 | 12.06 | 594 | 138312 | 125965 | 64233861 |
Intentional product misuse | 140.93 | 12.06 | 3 | 138903 | 72292 | 64287534 |
Malaise | 137.01 | 12.06 | 419 | 138487 | 395828 | 63963998 |
Anti-Muellerian hormone level decreased | 137.00 | 12.06 | 34 | 138872 | 70 | 64359756 |
Drug interaction | 133.06 | 12.06 | 372 | 138534 | 361711 | 63998115 |
Urticaria | 132.87 | 12.06 | 76 | 138830 | 147241 | 64212585 |
Myocardial infarction | 131.35 | 12.06 | 99 | 138807 | 165722 | 64194104 |
Epstein-Barr virus infection | 129.63 | 12.06 | 147 | 138759 | 12341 | 64347485 |
Hepatic failure | 127.27 | 12.06 | 332 | 138574 | 55062 | 64304764 |
Stomatitis | 127.03 | 12.06 | 520 | 138386 | 109085 | 64250741 |
Confusional state | 125.37 | 12.06 | 232 | 138674 | 260912 | 64098914 |
Rhabdomyolysis | 125.19 | 12.06 | 23 | 138883 | 91703 | 64268123 |
Gene mutation | 124.12 | 12.06 | 69 | 138837 | 2013 | 64357813 |
Psoriasis | 119.92 | 12.06 | 9 | 138897 | 71694 | 64288132 |
Fatigue | 119.80 | 12.06 | 1035 | 137871 | 747695 | 63612131 |
Depression | 119.49 | 12.06 | 131 | 138775 | 183160 | 64176666 |
Post transplant lymphoproliferative disorder | 119.45 | 12.06 | 124 | 138782 | 9420 | 64350406 |
Lymphopenia | 119.10 | 12.06 | 205 | 138701 | 25452 | 64334374 |
Therapeutic product effect decreased | 116.82 | 12.06 | 51 | 138855 | 115300 | 64244526 |
Pemphigus | 116.46 | 12.06 | 3 | 138903 | 60698 | 64299128 |
Venoocclusive disease | 116.22 | 12.06 | 84 | 138822 | 3901 | 64355925 |
Diffuse large B-cell lymphoma | 114.47 | 12.06 | 126 | 138780 | 10235 | 64349591 |
Contraindicated product administered | 113.50 | 12.06 | 45 | 138861 | 107784 | 64252042 |
Venoocclusive liver disease | 112.74 | 12.06 | 123 | 138783 | 9892 | 64349934 |
Bronchopulmonary aspergillosis | 109.69 | 12.06 | 168 | 138738 | 18917 | 64340909 |
Neoplasm recurrence | 109.47 | 12.06 | 79 | 138827 | 3660 | 64356166 |
Wound | 109.18 | 12.06 | 17 | 138889 | 76460 | 64283366 |
Cytomegalovirus infection | 109.08 | 12.06 | 245 | 138661 | 36954 | 64322872 |
Metastases to lymph nodes | 108.64 | 12.06 | 113 | 138793 | 8604 | 64351222 |
Asthma | 108.30 | 12.06 | 35 | 138871 | 95190 | 64264636 |
Discomfort | 104.70 | 12.06 | 23 | 138883 | 80855 | 64278971 |
Hospitalisation | 104.50 | 12.06 | 18 | 138888 | 75189 | 64284637 |
Cerebrovascular accident | 104.08 | 12.06 | 86 | 138820 | 137497 | 64222329 |
Bone pain | 104.08 | 12.06 | 280 | 138626 | 47292 | 64312534 |
Hypogammaglobulinaemia | 101.45 | 12.06 | 118 | 138788 | 10181 | 64349645 |
Myelopathy | 100.74 | 12.06 | 77 | 138829 | 3897 | 64355929 |
Cystitis haemorrhagic | 100.71 | 12.06 | 104 | 138802 | 7852 | 64351974 |
Stress | 100.09 | 12.06 | 8 | 138898 | 60526 | 64299300 |
Salivary gland cancer | 99.33 | 12.06 | 36 | 138870 | 363 | 64359463 |
Sinusitis | 98.79 | 12.06 | 101 | 138805 | 145827 | 64213999 |
Arthritis | 98.56 | 12.06 | 29 | 138877 | 83785 | 64276041 |
Acute lymphocytic leukaemia | 98.49 | 12.06 | 79 | 138827 | 4292 | 64355534 |
Bacteraemia | 98.41 | 12.06 | 194 | 138712 | 26717 | 64333109 |
Intestinal perforation | 98.34 | 12.06 | 142 | 138764 | 15171 | 64344655 |
Bradycardia | 98.28 | 12.06 | 67 | 138839 | 118152 | 64241674 |
Staphylococcal bacteraemia | 97.61 | 12.06 | 116 | 138790 | 10239 | 64349587 |
Hypoglycaemia | 97.12 | 12.06 | 36 | 138870 | 89856 | 64269970 |
Injection site erythema | 96.08 | 12.06 | 18 | 138888 | 70782 | 64289044 |
Glossodynia | 95.55 | 12.06 | 13 | 138893 | 64683 | 64295143 |
Respiratory failure | 94.11 | 12.06 | 632 | 138274 | 160551 | 64199275 |
Acute lymphocytic leukaemia recurrent | 93.35 | 12.06 | 74 | 138832 | 3952 | 64355874 |
Tremor | 93.26 | 12.06 | 109 | 138797 | 148121 | 64211705 |
Wheezing | 92.73 | 12.06 | 29 | 138877 | 80550 | 64279276 |
Suicide attempt | 92.30 | 12.06 | 20 | 138886 | 70987 | 64288839 |
Abdominal pain upper | 91.71 | 12.06 | 147 | 138759 | 174883 | 64184943 |
Bronchitis | 91.24 | 12.06 | 61 | 138845 | 108682 | 64251144 |
Herpes simplex | 91.13 | 12.06 | 113 | 138793 | 10423 | 64349403 |
Ascites | 90.73 | 12.06 | 317 | 138589 | 61684 | 64298142 |
Blood glucose increased | 90.72 | 12.06 | 49 | 138857 | 98024 | 64261802 |
Traumatic lung injury | 90.22 | 12.06 | 58 | 138848 | 2218 | 64357608 |
Hepatic enzyme increased | 89.02 | 12.06 | 89 | 138817 | 129854 | 64229972 |
Aspergillus infection | 88.30 | 12.06 | 140 | 138766 | 16239 | 64343587 |
Candida infection | 87.76 | 12.06 | 203 | 138703 | 31216 | 64328610 |
Pulmonary toxicity | 87.54 | 12.06 | 100 | 138806 | 8461 | 64351365 |
Heart rate decreased | 86.43 | 12.06 | 9 | 138897 | 55058 | 64304768 |
Gait disturbance | 85.20 | 12.06 | 150 | 138756 | 172005 | 64187821 |
Osteoarthritis | 84.05 | 12.06 | 17 | 138889 | 63319 | 64296507 |
Sweat gland tumour | 83.87 | 12.06 | 34 | 138872 | 475 | 64359351 |
Agranulocytosis | 83.61 | 12.06 | 225 | 138681 | 38004 | 64321822 |
Skin toxicity | 83.02 | 12.06 | 86 | 138820 | 6516 | 64353310 |
Inappropriate schedule of product administration | 82.63 | 12.06 | 48 | 138858 | 92238 | 64267588 |
Loss of personal independence in daily activities | 81.73 | 12.06 | 27 | 138879 | 72427 | 64287399 |
Myeloid leukaemia | 81.32 | 12.06 | 35 | 138871 | 573 | 64359253 |
Injury | 80.94 | 12.06 | 12 | 138894 | 55980 | 64303846 |
JC virus infection | 80.67 | 12.06 | 63 | 138843 | 3292 | 64356534 |
Nephropathy toxic | 80.06 | 12.06 | 139 | 138767 | 17375 | 64342451 |
Osteonecrosis | 79.51 | 12.06 | 183 | 138723 | 28046 | 64331780 |
Refractory anaemia with an excess of blasts | 79.26 | 12.06 | 38 | 138868 | 808 | 64359018 |
Balance disorder | 78.99 | 12.06 | 41 | 138865 | 83885 | 64275941 |
Metastasis | 78.58 | 12.06 | 78 | 138828 | 5617 | 64354209 |
Smooth muscle cell neoplasm | 78.41 | 12.06 | 38 | 138868 | 828 | 64358998 |
Suicidal ideation | 78.28 | 12.06 | 23 | 138883 | 66519 | 64293307 |
5q minus syndrome | 75.60 | 12.06 | 27 | 138879 | 260 | 64359566 |
Metastases to peritoneum | 75.47 | 12.06 | 62 | 138844 | 3485 | 64356341 |
Leukaemia | 74.52 | 12.06 | 72 | 138834 | 5016 | 64354810 |
Blood cholesterol increased | 74.08 | 12.06 | 10 | 138896 | 50056 | 64309770 |
Malignant transformation | 74.06 | 12.06 | 40 | 138866 | 1101 | 64358725 |
Injection site swelling | 72.67 | 12.06 | 4 | 138902 | 41349 | 64318477 |
Cytokine release syndrome | 72.38 | 12.06 | 147 | 138759 | 20682 | 64339144 |
Mobility decreased | 72.21 | 12.06 | 48 | 138858 | 85792 | 64274034 |
Small intestinal obstruction | 72.19 | 12.06 | 158 | 138748 | 23415 | 64336411 |
Bone marrow disorder | 72.19 | 12.06 | 55 | 138851 | 2770 | 64357056 |
Systemic candida | 71.71 | 12.06 | 72 | 138834 | 5257 | 64354569 |
Cardio-respiratory arrest | 71.36 | 12.06 | 64 | 138842 | 98329 | 64261497 |
Anaplastic lymphoma kinase gene mutation | 70.93 | 12.06 | 21 | 138885 | 103 | 64359723 |
Coronary artery disease | 70.89 | 12.06 | 21 | 138885 | 60412 | 64299414 |
Klebsiella infection | 70.88 | 12.06 | 113 | 138793 | 13168 | 64346658 |
Plasmacytoma | 70.76 | 12.06 | 62 | 138844 | 3808 | 64356018 |
Remission not achieved | 69.93 | 12.06 | 27 | 138879 | 329 | 64359497 |
Lung infiltration | 69.73 | 12.06 | 145 | 138761 | 20744 | 64339082 |
Heart rate increased | 69.41 | 12.06 | 66 | 138840 | 98609 | 64261217 |
Drug intolerance | 69.04 | 12.06 | 193 | 138713 | 187799 | 64172027 |
Aggression | 68.96 | 12.06 | 9 | 138897 | 46223 | 64313603 |
Injection site pruritus | 68.58 | 12.06 | 3 | 138903 | 37823 | 64322003 |
Cytogenetic abnormality | 68.55 | 12.06 | 37 | 138869 | 1017 | 64358809 |
Cardiomyopathy acute | 68.44 | 12.06 | 24 | 138882 | 218 | 64359608 |
Colitis | 68.43 | 12.06 | 279 | 138627 | 58395 | 64301431 |
Chest pain | 68.28 | 12.06 | 269 | 138637 | 235711 | 64124115 |
Viral haemorrhagic cystitis | 68.13 | 12.06 | 43 | 138863 | 1592 | 64358234 |
Psoriatic arthropathy | 68.12 | 12.06 | 7 | 138899 | 43274 | 64316552 |
Chronic myeloid leukaemia | 67.68 | 12.06 | 57 | 138849 | 3317 | 64356509 |
Myalgia | 67.46 | 12.06 | 151 | 138755 | 158466 | 64201360 |
Respiratory arrest | 66.71 | 12.06 | 16 | 138890 | 52969 | 64306857 |
Blood pressure fluctuation | 66.63 | 12.06 | 15 | 138891 | 51856 | 64307970 |
Nephrolithiasis | 66.39 | 12.06 | 8 | 138898 | 43675 | 64316151 |
Gastrointestinal toxicity | 66.34 | 12.06 | 69 | 138837 | 5253 | 64354573 |
Metastases to central nervous system | 65.67 | 12.06 | 112 | 138794 | 13800 | 64346026 |
Administration site extravasation | 65.61 | 12.06 | 36 | 138870 | 1023 | 64358803 |
Injection site bruising | 65.57 | 12.06 | 3 | 138903 | 36370 | 64323456 |
Injection site reaction | 65.19 | 12.06 | 11 | 138895 | 46653 | 64313173 |
Peripheral T-cell lymphoma unspecified | 64.84 | 12.06 | 30 | 138876 | 587 | 64359239 |
Irritable bowel syndrome | 64.49 | 12.06 | 4 | 138902 | 37365 | 64322461 |
Metastases to breast | 64.35 | 12.06 | 23 | 138883 | 222 | 64359604 |
Fibromyalgia | 64.24 | 12.06 | 3 | 138903 | 35728 | 64324098 |
Central nervous system lymphoma | 63.88 | 12.06 | 44 | 138862 | 1891 | 64357935 |
Musculoskeletal pain | 63.74 | 12.06 | 49 | 138857 | 81245 | 64278581 |
Chronic obstructive pulmonary disease | 63.53 | 12.06 | 37 | 138869 | 71011 | 64288815 |
Encephalopathy | 62.61 | 12.06 | 272 | 138634 | 58547 | 64301279 |
Acute hepatitis B | 61.87 | 12.06 | 26 | 138880 | 400 | 64359426 |
Drug reaction with eosinophilia and systemic symptoms | 61.51 | 12.06 | 20 | 138886 | 54197 | 64305629 |
End stage renal disease | 61.31 | 12.06 | 93 | 138813 | 10382 | 64349444 |
Incorrect dose administered | 61.29 | 12.06 | 27 | 138879 | 60738 | 64299088 |
Breast cancer recurrent | 61.01 | 12.06 | 48 | 138858 | 2535 | 64357291 |
Hallucination | 60.82 | 12.06 | 41 | 138865 | 72747 | 64287079 |
Memory impairment | 60.63 | 12.06 | 57 | 138849 | 85625 | 64274201 |
Neutrophil count abnormal | 60.32 | 12.06 | 50 | 138856 | 2846 | 64356980 |
Loss of consciousness | 60.07 | 12.06 | 145 | 138761 | 148220 | 64211606 |
Pneumonia | 59.74 | 12.06 | 1602 | 137304 | 557974 | 63801852 |
Infection reactivation | 59.68 | 12.06 | 43 | 138863 | 1987 | 64357839 |
Hyperhidrosis | 58.97 | 12.06 | 112 | 138794 | 124808 | 64235018 |
Hypersensitivity | 58.71 | 12.06 | 221 | 138685 | 196231 | 64163595 |
Lymphoma transformation | 58.64 | 12.06 | 21 | 138885 | 204 | 64359622 |
Mucosal toxicity | 58.27 | 12.06 | 26 | 138880 | 466 | 64359360 |
Recurrent cancer | 58.01 | 12.06 | 45 | 138861 | 2328 | 64357498 |
International normalised ratio increased | 58.00 | 12.06 | 51 | 138855 | 79116 | 64280710 |
Breast cancer metastatic | 57.42 | 12.06 | 74 | 138832 | 7095 | 64352731 |
Peripheral motor neuropathy | 57.17 | 12.06 | 49 | 138857 | 2921 | 64356905 |
Angioedema | 57.00 | 12.06 | 31 | 138875 | 61790 | 64298036 |
Agitation | 56.62 | 12.06 | 64 | 138842 | 88303 | 64271523 |
Fluid retention | 56.26 | 12.06 | 29 | 138877 | 59577 | 64300249 |
Death | 56.22 | 12.06 | 718 | 138188 | 481987 | 63877839 |
Blood creatine phosphokinase increased | 56.01 | 12.06 | 28 | 138878 | 58530 | 64301296 |
Premature menopause | 55.77 | 12.06 | 26 | 138880 | 518 | 64359308 |
Plasma cell leukaemia | 55.28 | 12.06 | 37 | 138869 | 1516 | 64358310 |
Pneumonia fungal | 55.08 | 12.06 | 81 | 138825 | 8796 | 64351030 |
Condition aggravated | 54.43 | 12.06 | 526 | 138380 | 371900 | 63987926 |
Extravasation | 54.28 | 12.06 | 49 | 138857 | 3131 | 64356695 |
Computerised tomogram thorax abnormal | 54.01 | 12.06 | 40 | 138866 | 1929 | 64357897 |
BK virus infection | 53.95 | 12.06 | 73 | 138833 | 7339 | 64352487 |
Enterococcal bacteraemia | 53.75 | 12.06 | 44 | 138862 | 2461 | 64357365 |
Nasal congestion | 53.44 | 12.06 | 31 | 138875 | 59627 | 64300199 |
Serotonin syndrome | 53.27 | 12.06 | 10 | 138896 | 39272 | 64320554 |
Varicella zoster virus infection | 53.18 | 12.06 | 53 | 138853 | 3835 | 64355991 |
Blood pressure systolic increased | 53.08 | 12.06 | 20 | 138886 | 49433 | 64310393 |
Post embolisation syndrome | 52.93 | 12.06 | 15 | 138891 | 61 | 64359765 |
Metastases to skin | 52.67 | 12.06 | 35 | 138871 | 1417 | 64358409 |
Gastrooesophageal reflux disease | 52.42 | 12.06 | 61 | 138845 | 83082 | 64276744 |
Neck pain | 52.30 | 12.06 | 34 | 138872 | 61499 | 64298327 |
Chloroma | 52.23 | 12.06 | 27 | 138879 | 678 | 64359148 |
Pneumocystis jirovecii infection | 51.77 | 12.06 | 42 | 138864 | 2319 | 64357507 |
Pneumatosis intestinalis | 51.65 | 12.06 | 60 | 138846 | 5169 | 64354657 |
Diarrhoea | 50.79 | 12.06 | 1178 | 137728 | 721526 | 63638300 |
Thrombotic microangiopathy | 50.28 | 12.06 | 111 | 138795 | 16544 | 64343282 |
Escherichia bacteraemia | 50.06 | 12.06 | 60 | 138846 | 5343 | 64354483 |
Palpitations | 49.91 | 12.06 | 93 | 138813 | 104395 | 64255431 |
Ileus paralytic | 49.66 | 12.06 | 75 | 138831 | 8340 | 64351486 |
Ovarian failure | 49.61 | 12.06 | 24 | 138882 | 521 | 64359305 |
Device related infection | 49.56 | 12.06 | 162 | 138744 | 30464 | 64329362 |
Drug withdrawal syndrome | 49.40 | 12.06 | 5 | 138901 | 31286 | 64328540 |
Abnormal behaviour | 49.07 | 12.06 | 7 | 138899 | 33615 | 64326211 |
Toxic cardiomyopathy | 48.83 | 12.06 | 21 | 138885 | 343 | 64359483 |
Unevaluable event | 48.50 | 12.06 | 24 | 138882 | 50465 | 64309361 |
Pericardial effusion | 48.44 | 12.06 | 190 | 138716 | 39064 | 64320762 |
Rash pruritic | 48.41 | 12.06 | 32 | 138874 | 57372 | 64302454 |
Dyspnoea | 48.12 | 12.06 | 1180 | 137726 | 717494 | 63642332 |
Drug clearance decreased | 47.97 | 12.06 | 42 | 138864 | 2577 | 64357249 |
Joint stiffness | 47.63 | 12.06 | 5 | 138901 | 30399 | 64329427 |
Toxic erythema of chemotherapy | 47.02 | 12.06 | 18 | 138888 | 214 | 64359612 |
Philadelphia chromosome positive | 46.78 | 12.06 | 24 | 138882 | 593 | 64359233 |
Gastrosplenic fistula | 46.27 | 12.06 | 14 | 138892 | 75 | 64359751 |
Pneumonia klebsiella | 46.17 | 12.06 | 50 | 138856 | 3987 | 64355839 |
Road traffic accident | 45.82 | 12.06 | 6 | 138900 | 30739 | 64329087 |
Hyperkalaemia | 45.71 | 12.06 | 93 | 138813 | 101036 | 64258790 |
Escherichia infection | 45.69 | 12.06 | 101 | 138805 | 15067 | 64344759 |
Ventricular hypokinesia | 45.50 | 12.06 | 69 | 138837 | 7700 | 64352126 |
Oedema peripheral | 45.49 | 12.06 | 266 | 138640 | 210051 | 64149775 |
Pseudomonas infection | 45.03 | 12.06 | 111 | 138795 | 17772 | 64342054 |
Enterococcal infection | 44.82 | 12.06 | 95 | 138811 | 13771 | 64346055 |
Impaired healing | 44.24 | 12.06 | 39 | 138867 | 60434 | 64299392 |
Ileus | 44.15 | 12.06 | 129 | 138777 | 22837 | 64336989 |
Blood stem cell transplant failure | 44.04 | 12.06 | 22 | 138884 | 513 | 64359313 |
Product prescribing error | 43.72 | 12.06 | 11 | 138895 | 35258 | 64324568 |
Sopor | 43.70 | 12.06 | 6 | 138900 | 29655 | 64330171 |
Lower respiratory tract infection | 43.63 | 12.06 | 86 | 138820 | 94528 | 64265298 |
Product use issue | 43.49 | 12.06 | 509 | 138397 | 151206 | 64208620 |
Vision blurred | 43.48 | 12.06 | 80 | 138826 | 90236 | 64269590 |
Blister | 43.33 | 12.06 | 67 | 138839 | 80900 | 64278926 |
Surgery | 43.28 | 12.06 | 5 | 138901 | 28208 | 64331618 |
Toxicity to various agents | 43.28 | 12.06 | 538 | 138368 | 362975 | 63996851 |
Blood lactate dehydrogenase increased | 43.19 | 12.06 | 163 | 138743 | 32915 | 64326911 |
Acute myelomonocytic leukaemia | 43.13 | 12.06 | 18 | 138888 | 272 | 64359554 |
Adverse drug reaction | 43.09 | 12.06 | 22 | 138884 | 45442 | 64314384 |
Myelitis | 43.00 | 12.06 | 36 | 138870 | 2078 | 64357748 |
Cataract | 42.66 | 12.06 | 29 | 138877 | 51233 | 64308593 |
Epstein-Barr virus associated lymphoma | 42.58 | 12.06 | 26 | 138880 | 907 | 64358919 |
Accidental overdose | 42.51 | 12.06 | 10 | 138896 | 33547 | 64326279 |
Hepatotoxicity | 41.91 | 12.06 | 184 | 138722 | 39778 | 64320048 |
White blood cell count abnormal | 41.88 | 12.06 | 52 | 138854 | 4802 | 64355024 |
Colony stimulating factor therapy | 41.87 | 12.06 | 21 | 138885 | 494 | 64359332 |
Heart rate irregular | 41.70 | 12.06 | 5 | 138901 | 27408 | 64332418 |
Infection | 41.51 | 12.06 | 593 | 138313 | 184287 | 64175539 |
Treatment noncompliance | 41.27 | 12.06 | 21 | 138885 | 43461 | 64316365 |
Swollen tongue | 41.26 | 12.06 | 12 | 138894 | 34942 | 64324884 |
Blood pressure decreased | 40.92 | 12.06 | 77 | 138829 | 86122 | 64273704 |
Intertrigo | 40.91 | 12.06 | 22 | 138884 | 600 | 64359226 |
Flagellate dermatitis | 40.79 | 12.06 | 16 | 138890 | 204 | 64359622 |
Perineal necrosis | 40.74 | 12.06 | 14 | 138892 | 119 | 64359707 |
Alveolar soft part sarcoma | 40.52 | 12.06 | 13 | 138893 | 87 | 64359739 |
Atelectasis | 40.38 | 12.06 | 140 | 138766 | 27126 | 64332700 |
Liver function test abnormal | 40.30 | 12.06 | 41 | 138865 | 59360 | 64300466 |
C-reactive protein abnormal | 40.24 | 12.06 | 7 | 138899 | 29040 | 64330786 |
Clonal evolution | 40.23 | 12.06 | 16 | 138890 | 212 | 64359614 |
Staphylococcal sepsis | 40.11 | 12.06 | 87 | 138819 | 12812 | 64347014 |
Lymphadenitis | 40.04 | 12.06 | 45 | 138861 | 3740 | 64356086 |
Swelling face | 39.96 | 12.06 | 41 | 138865 | 59125 | 64300701 |
Lymphoma | 39.95 | 12.06 | 91 | 138815 | 13850 | 64345976 |
Refractory cancer | 39.70 | 12.06 | 16 | 138890 | 220 | 64359606 |
Emotional distress | 39.65 | 12.06 | 14 | 138892 | 36024 | 64323802 |
Amnesia | 39.25 | 12.06 | 28 | 138878 | 48241 | 64311585 |
Gastric perforation | 39.19 | 12.06 | 43 | 138863 | 3480 | 64356346 |
Withdrawal syndrome | 39.13 | 12.06 | 3 | 138903 | 23489 | 64336337 |
Hypoxia | 39.10 | 12.06 | 324 | 138582 | 87825 | 64272001 |
Clostridium difficile infection | 39.07 | 12.06 | 168 | 138738 | 35995 | 64323831 |
Visual impairment | 38.97 | 12.06 | 62 | 138844 | 74015 | 64285811 |
Osteosarcoma metastatic | 38.77 | 12.06 | 11 | 138895 | 45 | 64359781 |
Peripheral sensorimotor neuropathy | 38.65 | 12.06 | 37 | 138869 | 2548 | 64357278 |
Hepatitis E | 38.65 | 12.06 | 36 | 138870 | 2395 | 64357431 |
Endocarditis noninfective | 38.54 | 12.06 | 15 | 138891 | 187 | 64359639 |
B-cell lymphoma refractory | 38.52 | 12.06 | 13 | 138893 | 104 | 64359722 |
Cutaneous calcification | 38.41 | 12.06 | 13 | 138893 | 105 | 64359721 |
Cytomegalovirus viraemia | 38.31 | 12.06 | 77 | 138829 | 10751 | 64349075 |
Escherichia sepsis | 38.28 | 12.06 | 61 | 138845 | 7104 | 64352722 |
Gastritis bacterial | 38.24 | 12.06 | 17 | 138889 | 302 | 64359524 |
Subdural hygroma | 38.19 | 12.06 | 19 | 138887 | 439 | 64359387 |
Osteosarcoma recurrent | 38.14 | 12.06 | 10 | 138896 | 28 | 64359798 |
Ganglioneuroblastoma | 38.14 | 12.06 | 10 | 138896 | 28 | 64359798 |
Gastrointestinal fungal infection | 38.10 | 12.06 | 18 | 138888 | 370 | 64359456 |
Gastric stenosis | 38.09 | 12.06 | 13 | 138893 | 108 | 64359718 |
West Nile viral infection | 37.92 | 12.06 | 24 | 138882 | 893 | 64358933 |
Cytomegalovirus infection reactivation | 37.87 | 12.06 | 54 | 138852 | 5702 | 64354124 |
Chemotherapy | 37.76 | 12.06 | 29 | 138877 | 1478 | 64358348 |
Electrocardiogram QT prolonged | 37.69 | 12.06 | 71 | 138835 | 79377 | 64280449 |
Haematopoietic stem cell mobilisation | 37.57 | 12.06 | 15 | 138891 | 201 | 64359625 |
Head injury | 37.45 | 12.06 | 12 | 138894 | 32830 | 64326996 |
Sleep disorder | 37.43 | 12.06 | 44 | 138862 | 59665 | 64300161 |
Nervousness | 37.06 | 12.06 | 9 | 138897 | 29547 | 64330279 |
Ototoxicity | 37.02 | 12.06 | 37 | 138869 | 2686 | 64357140 |
Therapy cessation | 36.82 | 12.06 | 12 | 138894 | 32477 | 64327349 |
Autoimmune neutropenia | 36.82 | 12.06 | 18 | 138888 | 400 | 64359426 |
Transient ischaemic attack | 36.75 | 12.06 | 25 | 138881 | 44157 | 64315669 |
Lactic acidosis | 36.66 | 12.06 | 47 | 138859 | 61363 | 64298463 |
Restlessness | 36.60 | 12.06 | 20 | 138886 | 39765 | 64320061 |
Gait inability | 36.57 | 12.06 | 23 | 138883 | 42345 | 64317481 |
Cerebral venous sinus thrombosis | 36.52 | 12.06 | 31 | 138875 | 1824 | 64358002 |
Primary cardiac lymphoma | 36.44 | 12.06 | 9 | 138897 | 18 | 64359808 |
Metastases to spine | 36.31 | 12.06 | 42 | 138864 | 3601 | 64356225 |
Capillary leak syndrome | 36.25 | 12.06 | 40 | 138866 | 3257 | 64356569 |
Clostridium difficile colitis | 36.25 | 12.06 | 135 | 138771 | 27088 | 64332738 |
Renal tubular disorder | 36.24 | 12.06 | 54 | 138852 | 5933 | 64353893 |
Irritability | 36.01 | 12.06 | 17 | 138889 | 36729 | 64323097 |
Nail pigmentation | 35.90 | 12.06 | 16 | 138890 | 286 | 64359540 |
Weight decreased | 35.85 | 12.06 | 418 | 138488 | 285321 | 64074505 |
Mucormycosis | 35.84 | 12.06 | 60 | 138846 | 7281 | 64352545 |
Lip swelling | 35.79 | 12.06 | 12 | 138894 | 31895 | 64327931 |
Metastases to retroperitoneum | 35.69 | 12.06 | 17 | 138889 | 356 | 64359470 |
Hydrothorax | 35.53 | 12.06 | 26 | 138880 | 1231 | 64358595 |
Glioma | 35.24 | 12.06 | 19 | 138887 | 521 | 64359305 |
Alopecia | 35.05 | 12.06 | 211 | 138695 | 165479 | 64194347 |
Depressed level of consciousness | 35.03 | 12.06 | 77 | 138829 | 81359 | 64278467 |
Strongyloidiasis | 34.86 | 12.06 | 38 | 138868 | 3052 | 64356774 |
Pseudomonal sepsis | 34.73 | 12.06 | 49 | 138857 | 5123 | 64354703 |
Blast cells present | 34.63 | 12.06 | 22 | 138884 | 824 | 64359002 |
Depressed mood | 34.39 | 12.06 | 23 | 138883 | 40989 | 64318837 |
Necrotising gastritis | 34.37 | 12.06 | 11 | 138895 | 73 | 64359753 |
Helicobacter infection | 34.26 | 12.06 | 20 | 138886 | 38342 | 64321484 |
Amniotic fluid index decreased | 34.25 | 12.06 | 8 | 138898 | 11 | 64359815 |
Alveolitis | 34.21 | 12.06 | 41 | 138865 | 3651 | 64356175 |
Invasive ductal breast carcinoma | 34.20 | 12.06 | 48 | 138858 | 4994 | 64354832 |
Hypertriglyceridaemia | 34.19 | 12.06 | 75 | 138831 | 11130 | 64348696 |
Fanconi syndrome | 34.04 | 12.06 | 34 | 138872 | 2467 | 64357359 |
Faeces discoloured | 33.94 | 12.06 | 7 | 138899 | 25722 | 64334104 |
Labelled drug-drug interaction medication error | 33.62 | 12.06 | 4 | 138902 | 22058 | 64337768 |
Haemorrhage | 33.34 | 12.06 | 76 | 138830 | 79275 | 64280551 |
Clostridium bacteraemia | 33.31 | 12.06 | 15 | 138891 | 275 | 64359551 |
COVID-19 pneumonia | 32.97 | 12.06 | 94 | 138812 | 16410 | 64343416 |
Therapy non-responder | 32.95 | 12.06 | 249 | 138657 | 65650 | 64294176 |
Organising pneumonia | 32.76 | 12.06 | 65 | 138841 | 8990 | 64350836 |
B-cell lymphoma | 32.72 | 12.06 | 49 | 138857 | 5408 | 64354418 |
Autoimmune lymphoproliferative syndrome | 32.71 | 12.06 | 13 | 138893 | 172 | 64359654 |
Plasma cell myeloma recurrent | 32.62 | 12.06 | 42 | 138864 | 4023 | 64355803 |
Bursitis | 32.48 | 12.06 | 4 | 138902 | 21481 | 64338345 |
Haematoma | 32.44 | 12.06 | 31 | 138875 | 46219 | 64313607 |
Pneumothorax spontaneous | 32.30 | 12.06 | 23 | 138883 | 1043 | 64358783 |
Hypoaesthesia | 32.20 | 12.06 | 172 | 138734 | 138936 | 64220890 |
Urinary tract infection | 32.15 | 12.06 | 331 | 138575 | 231265 | 64128561 |
Squamous cell carcinoma of the oral cavity | 31.94 | 12.06 | 17 | 138889 | 454 | 64359372 |
Limb injury | 31.83 | 12.06 | 6 | 138900 | 23499 | 64336327 |
Product administration error | 31.70 | 12.06 | 10 | 138896 | 27633 | 64332193 |
Influenza | 31.70 | 12.06 | 120 | 138786 | 106411 | 64253415 |
Secondary immunodeficiency | 31.61 | 12.06 | 34 | 138872 | 2690 | 64357136 |
Hepatitis C RNA increased | 31.61 | 12.06 | 16 | 138890 | 384 | 64359442 |
Acute lung injury | 31.54 | 12.06 | 34 | 138872 | 2697 | 64357129 |
Unintentional medical device removal | 31.50 | 12.06 | 54 | 138852 | 6680 | 64353146 |
Large intestinal ulcer perforation | 31.16 | 12.06 | 10 | 138896 | 67 | 64359759 |
Nasal abscess | 31.10 | 12.06 | 12 | 138894 | 146 | 64359680 |
Dementia | 31.07 | 12.06 | 4 | 138902 | 20762 | 64339064 |
Paraparesis | 31.00 | 12.06 | 38 | 138868 | 3464 | 64356362 |
Back pain | 30.98 | 12.06 | 367 | 138539 | 249804 | 64110022 |
Lethargy | 30.93 | 12.06 | 69 | 138837 | 72525 | 64287301 |
Bone marrow infiltration | 30.92 | 12.06 | 17 | 138889 | 485 | 64359341 |
Rhinorrhoea | 30.79 | 12.06 | 51 | 138855 | 59918 | 64299908 |
Central nervous system enteroviral infection | 30.78 | 12.06 | 10 | 138896 | 70 | 64359756 |
Vocal cord paralysis | 30.74 | 12.06 | 30 | 138876 | 2116 | 64357710 |
Abdominal neoplasm | 30.73 | 12.06 | 16 | 138890 | 408 | 64359418 |
Viral load increased | 30.56 | 12.06 | 32 | 138874 | 2455 | 64357371 |
Hepatosplenic candidiasis | 30.33 | 12.06 | 17 | 138889 | 504 | 64359322 |
Influenza like illness | 30.28 | 12.06 | 54 | 138852 | 61648 | 64298178 |
Clonal haematopoiesis | 30.23 | 12.06 | 7 | 138899 | 9 | 64359817 |
Therapy responder | 30.14 | 12.06 | 16 | 138890 | 425 | 64359401 |
Disorientation | 30.06 | 12.06 | 46 | 138860 | 55782 | 64304044 |
Hepatitis B DNA increased | 29.89 | 12.06 | 18 | 138888 | 612 | 64359214 |
Premature delivery | 29.78 | 12.06 | 98 | 138808 | 18491 | 64341335 |
Eosinophilia | 29.78 | 12.06 | 23 | 138883 | 38053 | 64321773 |
Mesenteric abscess | 29.74 | 12.06 | 11 | 138895 | 118 | 64359708 |
Anastomotic leak | 29.63 | 12.06 | 21 | 138885 | 945 | 64358881 |
Ear infection | 29.59 | 12.06 | 7 | 138899 | 23397 | 64336429 |
Osteomyelitis bacterial | 29.47 | 12.06 | 16 | 138890 | 445 | 64359381 |
Osteosarcoma | 29.45 | 12.06 | 14 | 138892 | 292 | 64359534 |
Bone lesion | 29.20 | 12.06 | 45 | 138861 | 5092 | 64354734 |
Abortion spontaneous | 29.01 | 12.06 | 9 | 138897 | 25134 | 64334692 |
Metastases to bone marrow | 28.92 | 12.06 | 18 | 138888 | 650 | 64359176 |
Meningitis cryptococcal | 28.84 | 12.06 | 34 | 138872 | 2975 | 64356851 |
Metastases to pleura | 28.81 | 12.06 | 23 | 138883 | 1241 | 64358585 |
Leukoerythroblastosis | 28.73 | 12.06 | 13 | 138893 | 241 | 64359585 |
VIth nerve paresis | 28.72 | 12.06 | 11 | 138895 | 131 | 64359695 |
Dry mouth | 28.65 | 12.06 | 54 | 138852 | 60364 | 64299462 |
Unresponsive to stimuli | 28.62 | 12.06 | 40 | 138866 | 50353 | 64309473 |
Metastases to spleen | 28.08 | 12.06 | 16 | 138890 | 490 | 64359336 |
Cholelithiasis | 28.02 | 12.06 | 34 | 138872 | 45472 | 64314354 |
Migraine | 28.01 | 12.06 | 58 | 138848 | 62619 | 64297207 |
Left ventricular dilatation | 27.99 | 12.06 | 20 | 138886 | 912 | 64358914 |
Ovarian cancer recurrent | 27.70 | 12.06 | 14 | 138892 | 335 | 64359491 |
Chemotherapeutic drug level increased | 27.58 | 12.06 | 14 | 138892 | 338 | 64359488 |
Perineal infection | 27.55 | 12.06 | 14 | 138892 | 339 | 64359487 |
Product quality issue | 27.38 | 12.06 | 15 | 138891 | 29784 | 64330042 |
Adrenocortical carcinoma | 27.35 | 12.06 | 9 | 138897 | 66 | 64359760 |
Metastases to meninges | 27.30 | 12.06 | 32 | 138874 | 2783 | 64357043 |
Respiratory syncytial virus infection | 27.30 | 12.06 | 53 | 138853 | 7215 | 64352611 |
Neutropenic infection | 27.27 | 12.06 | 27 | 138879 | 1938 | 64357888 |
T-cell type acute leukaemia | 27.18 | 12.06 | 11 | 138895 | 153 | 64359673 |
Oesophageal candidiasis | 27.16 | 12.06 | 56 | 138850 | 7961 | 64351865 |
Muscle rigidity | 27.05 | 12.06 | 3 | 138903 | 17470 | 64342356 |
Mood swings | 27.04 | 12.06 | 3 | 138903 | 17465 | 64342361 |
Rhinovirus infection | 27.02 | 12.06 | 48 | 138858 | 6108 | 64353718 |
Enterococcal sepsis | 26.98 | 12.06 | 30 | 138876 | 2464 | 64357362 |
Chronic myelomonocytic leukaemia | 26.90 | 12.06 | 18 | 138888 | 737 | 64359089 |
Nodular regenerative hyperplasia | 26.89 | 12.06 | 19 | 138887 | 851 | 64358975 |
Vena cava thrombosis | 26.80 | 12.06 | 30 | 138876 | 2482 | 64357344 |
Dry skin | 26.74 | 12.06 | 43 | 138863 | 51118 | 64308708 |
Burning sensation | 26.66 | 12.06 | 41 | 138865 | 49623 | 64310203 |
Recall phenomenon | 26.62 | 12.06 | 20 | 138886 | 986 | 64358840 |
Myasthenia gravis crisis | 26.62 | 12.06 | 19 | 138887 | 865 | 64358961 |
Throat irritation | 26.56 | 12.06 | 19 | 138887 | 32692 | 64327134 |
Localised infection | 26.55 | 12.06 | 16 | 138890 | 30145 | 64329681 |
Extrapyramidal disorder | 26.46 | 12.06 | 5 | 138901 | 19547 | 64340279 |
Stem cell transplant | 26.43 | 12.06 | 35 | 138871 | 3446 | 64356380 |
Gastric disorder | 26.39 | 12.06 | 15 | 138891 | 29182 | 64330644 |
Bacterial sepsis | 26.35 | 12.06 | 53 | 138853 | 7404 | 64352422 |
Eye pain | 26.16 | 12.06 | 18 | 138888 | 31607 | 64328219 |
Metastases to soft tissue | 26.16 | 12.06 | 14 | 138892 | 378 | 64359448 |
Flatulence | 26.09 | 12.06 | 23 | 138883 | 35643 | 64324183 |
Intussusception | 26.07 | 12.06 | 19 | 138887 | 894 | 64358932 |
Joint range of motion decreased | 26.06 | 12.06 | 5 | 138901 | 19338 | 64340488 |
Type 2 diabetes mellitus | 26.04 | 12.06 | 21 | 138885 | 33999 | 64325827 |
Photosensitivity reaction | 26.02 | 12.06 | 4 | 138902 | 18169 | 64341657 |
Fungal oesophagitis | 25.98 | 12.06 | 18 | 138888 | 781 | 64359045 |
Thyroid dermatopathy | 25.86 | 12.06 | 7 | 138899 | 23 | 64359803 |
Eczema | 25.83 | 12.06 | 16 | 138890 | 29704 | 64330122 |
Mass | 25.80 | 12.06 | 82 | 138824 | 15194 | 64344632 |
Diabetes mellitus inadequate control | 25.76 | 12.06 | 7 | 138899 | 21314 | 64338512 |
Heart rate abnormal | 25.72 | 12.06 | 42 | 138864 | 4993 | 64354833 |
Biliary-bronchial fistula | 25.71 | 12.06 | 5 | 138901 | 0 | 64359826 |
Orthostatic hypotension | 25.65 | 12.06 | 38 | 138868 | 46700 | 64313126 |
Oxygen saturation decreased | 25.65 | 12.06 | 131 | 138775 | 107045 | 64252781 |
Leukaemic lymphoma | 25.64 | 12.06 | 9 | 138897 | 82 | 64359744 |
Red blood cell sedimentation rate increased | 25.55 | 12.06 | 18 | 138888 | 31217 | 64328609 |
Carotid intima-media thickness increased | 25.45 | 12.06 | 9 | 138897 | 84 | 64359742 |
Crying | 25.42 | 12.06 | 6 | 138900 | 20084 | 64339742 |
Body dysmorphic disorder | 25.38 | 12.06 | 12 | 138894 | 247 | 64359579 |
Pericarditis | 25.36 | 12.06 | 61 | 138845 | 62455 | 64297371 |
Therapy interrupted | 25.32 | 12.06 | 6 | 138900 | 20030 | 64339796 |
Subclavian vein thrombosis | 25.32 | 12.06 | 28 | 138878 | 2286 | 64357540 |
Vertigo | 25.21 | 12.06 | 56 | 138850 | 58955 | 64300871 |
Leukoencephalopathy | 25.19 | 12.06 | 50 | 138856 | 6917 | 64352909 |
Acute biphenotypic leukaemia | 25.18 | 12.06 | 10 | 138896 | 132 | 64359694 |
Lymphocytosis | 25.18 | 12.06 | 35 | 138871 | 3609 | 64356217 |
Nightmare | 25.16 | 12.06 | 7 | 138899 | 20986 | 64338840 |
Iron deficiency anaemia | 24.96 | 12.06 | 8 | 138898 | 21881 | 64337945 |
Amenorrhoea | 24.95 | 12.06 | 48 | 138858 | 6491 | 64353335 |
Meningitis tuberculous | 24.86 | 12.06 | 20 | 138886 | 1091 | 64358735 |
Adverse event | 24.86 | 12.06 | 29 | 138877 | 39460 | 64320366 |
Cardiac dysfunction | 24.78 | 12.06 | 32 | 138874 | 3074 | 64356752 |
Tumour necrosis | 24.68 | 12.06 | 24 | 138882 | 1685 | 64358141 |
Diabetic ketoacidosis | 24.67 | 12.06 | 17 | 138889 | 29828 | 64329998 |
Ovarian epithelial cancer recurrent | 24.63 | 12.06 | 6 | 138900 | 11 | 64359815 |
Rectal haemorrhage | 24.54 | 12.06 | 61 | 138845 | 61756 | 64298070 |
Venous thrombosis | 24.54 | 12.06 | 47 | 138859 | 6334 | 64353492 |
Pyomyositis | 24.52 | 12.06 | 15 | 138891 | 525 | 64359301 |
Skin mass | 24.51 | 12.06 | 50 | 138856 | 7056 | 64352770 |
Respiratory tract congestion | 24.46 | 12.06 | 3 | 138903 | 16162 | 64343664 |
Infusion site streaking | 24.44 | 12.06 | 14 | 138892 | 433 | 64359393 |
Cutaneous T-cell lymphoma recurrent | 24.39 | 12.06 | 8 | 138898 | 58 | 64359768 |
Hip fracture | 24.38 | 12.06 | 14 | 138892 | 27085 | 64332741 |
Glioblastoma multiforme | 24.35 | 12.06 | 20 | 138886 | 1124 | 64358702 |
Respiratory depression | 24.30 | 12.06 | 10 | 138896 | 23433 | 64336393 |
Computerised tomogram thorax | 24.27 | 12.06 | 10 | 138896 | 146 | 64359680 |
Blood urine present | 24.17 | 12.06 | 5 | 138901 | 18335 | 64341491 |
Device related thrombosis | 24.15 | 12.06 | 26 | 138880 | 2059 | 64357767 |
Blood potassium increased | 23.98 | 12.06 | 13 | 138893 | 25967 | 64333859 |
Coma | 23.97 | 12.06 | 102 | 138804 | 87513 | 64272313 |
Eye swelling | 23.93 | 12.06 | 9 | 138897 | 22272 | 64337554 |
Marginal zone lymphoma recurrent | 23.87 | 12.06 | 7 | 138899 | 33 | 64359793 |
Gallbladder disorder | 23.82 | 12.06 | 4 | 138902 | 17026 | 64342800 |
Combined immunodeficiency | 23.82 | 12.06 | 9 | 138897 | 103 | 64359723 |
B precursor type acute leukaemia | 23.75 | 12.06 | 12 | 138894 | 287 | 64359539 |
Haematochezia | 23.71 | 12.06 | 69 | 138837 | 66304 | 64293522 |
Intestinal atresia | 23.70 | 12.06 | 8 | 138898 | 64 | 64359762 |
T-cell lymphoma | 23.57 | 12.06 | 20 | 138886 | 1176 | 64358650 |
Respiratory distress | 23.55 | 12.06 | 193 | 138713 | 52138 | 64307688 |
Hypertension | 23.39 | 12.06 | 405 | 138501 | 258856 | 64100970 |
Oedema | 23.37 | 12.06 | 110 | 138796 | 91825 | 64268001 |
Epstein Barr virus positive mucocutaneous ulcer | 23.36 | 12.06 | 16 | 138890 | 681 | 64359145 |
Renal disorder | 23.32 | 12.06 | 25 | 138881 | 35340 | 64324486 |
Sarcoidosis | 23.31 | 12.06 | 45 | 138861 | 6101 | 64353725 |
Panic attack | 23.29 | 12.06 | 8 | 138898 | 20945 | 64338881 |
Sarcoma metastatic | 23.28 | 12.06 | 8 | 138898 | 68 | 64359758 |
Kidney infection | 23.23 | 12.06 | 5 | 138901 | 17833 | 64341993 |
Poisoning | 23.23 | 12.06 | 9 | 138897 | 21870 | 64337956 |
Blood urea increased | 23.18 | 12.06 | 37 | 138869 | 44116 | 64315710 |
Retinal haemorrhage | 23.12 | 12.06 | 50 | 138856 | 7348 | 64352478 |
Acute respiratory distress syndrome | 22.88 | 12.06 | 153 | 138753 | 38782 | 64321044 |
Acute hepatic failure | 22.81 | 12.06 | 114 | 138792 | 25998 | 64333828 |
Ankle brachial index decreased | 22.78 | 12.06 | 8 | 138898 | 73 | 64359753 |
Gastrointestinal haemorrhage | 22.77 | 12.06 | 179 | 138727 | 132133 | 64227693 |
Disorder of orbit | 22.72 | 12.06 | 9 | 138897 | 118 | 64359708 |
Listeria sepsis | 22.60 | 12.06 | 15 | 138891 | 606 | 64359220 |
Pulse waveform abnormal | 22.59 | 12.06 | 8 | 138898 | 75 | 64359751 |
Tooth disorder | 22.51 | 12.06 | 10 | 138896 | 22392 | 64337434 |
Abdominal abscess | 22.51 | 12.06 | 45 | 138861 | 6259 | 64353567 |
Blood creatinine increased | 22.31 | 12.06 | 186 | 138720 | 135596 | 64224230 |
Hyperferritinaemia | 22.26 | 12.06 | 14 | 138892 | 515 | 64359311 |
Cerebral haemangioma | 22.18 | 12.06 | 9 | 138897 | 126 | 64359700 |
Herpes simplex encephalitis | 22.17 | 12.06 | 15 | 138891 | 626 | 64359200 |
Tendonitis | 22.11 | 12.06 | 8 | 138898 | 20274 | 64339552 |
Mucosal disorder | 22.05 | 12.06 | 30 | 138876 | 3032 | 64356794 |
Disseminated intravascular coagulation | 22.04 | 12.06 | 132 | 138774 | 32216 | 64327610 |
Colitis ulcerative | 22.03 | 12.06 | 11 | 138895 | 23017 | 64336809 |
Fear | 21.91 | 12.06 | 8 | 138898 | 20163 | 64339663 |
Acute monocytic leukaemia | 21.91 | 12.06 | 13 | 138893 | 430 | 64359396 |
Refractory cytopenia with multilineage dysplasia | 21.88 | 12.06 | 11 | 138895 | 260 | 64359566 |
Pleuroparenchymal fibroelastosis | 21.88 | 12.06 | 6 | 138900 | 21 | 64359805 |
Cardiac arrest | 21.86 | 12.06 | 219 | 138687 | 153845 | 64205981 |
Blood HIV RNA increased | 21.73 | 12.06 | 21 | 138885 | 1463 | 64358363 |
Klebsiella bacteraemia | 21.70 | 12.06 | 26 | 138880 | 2314 | 64357512 |
Medication error | 21.69 | 12.06 | 47 | 138859 | 49919 | 64309907 |
Lentigo | 21.67 | 12.06 | 13 | 138893 | 439 | 64359387 |
Vascular injury | 21.62 | 12.06 | 18 | 138888 | 1031 | 64358795 |
Mediastinum neoplasm | 21.62 | 12.06 | 8 | 138898 | 86 | 64359740 |
Fungal infection | 21.60 | 12.06 | 137 | 138769 | 34114 | 64325712 |
B-cell type acute leukaemia | 21.56 | 12.06 | 13 | 138893 | 443 | 64359383 |
Geotrichum infection | 21.56 | 12.06 | 17 | 138889 | 901 | 64358925 |
Hallucination, auditory | 21.55 | 12.06 | 5 | 138901 | 16934 | 64342892 |
Cellulitis gangrenous | 21.54 | 12.06 | 11 | 138895 | 269 | 64359557 |
Hyperpyrexia | 21.53 | 12.06 | 39 | 138867 | 5038 | 64354788 |
Feeling hot | 21.48 | 12.06 | 41 | 138865 | 45622 | 64314204 |
Dysgeusia | 21.48 | 12.06 | 43 | 138863 | 47004 | 64312822 |
Neoplasm | 21.38 | 12.06 | 47 | 138859 | 6984 | 64352842 |
Pulmonary embolism | 21.36 | 12.06 | 438 | 138468 | 145918 | 64213908 |
Injection site rash | 21.36 | 12.06 | 4 | 138902 | 15738 | 64344088 |
Hot flush | 21.33 | 12.06 | 42 | 138864 | 46193 | 64313633 |
Fungaemia | 21.30 | 12.06 | 33 | 138873 | 3752 | 64356074 |
Rhabdomyosarcoma | 21.21 | 12.06 | 9 | 138897 | 142 | 64359684 |
Duodenal stenosis | 21.21 | 12.06 | 15 | 138891 | 673 | 64359153 |
Taeniasis | 21.19 | 12.06 | 7 | 138899 | 52 | 64359774 |
Gastroenteritis viral | 21.14 | 12.06 | 8 | 138898 | 19721 | 64340105 |
Body temperature decreased | 21.13 | 12.06 | 15 | 138891 | 25913 | 64333913 |
Leukaemia recurrent | 21.13 | 12.06 | 27 | 138879 | 2567 | 64357259 |
Hypersomnia | 21.11 | 12.06 | 8 | 138898 | 19709 | 64340117 |
Encephalitis enteroviral | 21.10 | 12.06 | 9 | 138897 | 144 | 64359682 |
Respiratory tract infection fungal | 20.99 | 12.06 | 18 | 138888 | 1074 | 64358752 |
Vulvovaginal inflammation | 20.95 | 12.06 | 13 | 138893 | 467 | 64359359 |
Procedural pain | 20.91 | 12.06 | 4 | 138902 | 15504 | 64344322 |
Quadriplegia | 20.91 | 12.06 | 29 | 138877 | 2984 | 64356842 |
Rhabdomyosarcoma recurrent | 20.91 | 12.06 | 8 | 138898 | 95 | 64359731 |
Mucoepidermoid carcinoma of salivary gland | 20.83 | 12.06 | 8 | 138898 | 96 | 64359730 |
Toxic encephalopathy | 20.69 | 12.06 | 57 | 138849 | 9758 | 64350068 |
Trichodysplasia spinulosa | 20.67 | 12.06 | 15 | 138891 | 701 | 64359125 |
Erythropenia | 20.61 | 12.06 | 12 | 138894 | 383 | 64359443 |
Pneumonia cytomegaloviral | 20.57 | 12.06 | 35 | 138871 | 4304 | 64355522 |
Delirium | 20.54 | 12.06 | 78 | 138828 | 69116 | 64290710 |
Device dislocation | 20.44 | 12.06 | 10 | 138896 | 21168 | 64338658 |
Sneezing | 20.43 | 12.06 | 4 | 138902 | 15247 | 64344579 |
Metabolic acidosis | 20.42 | 12.06 | 81 | 138825 | 70877 | 64288949 |
Transformation to acute myeloid leukaemia | 20.34 | 12.06 | 16 | 138890 | 845 | 64358981 |
Immunosuppression | 20.31 | 12.06 | 60 | 138846 | 10686 | 64349140 |
Hormone receptor positive breast cancer | 20.23 | 12.06 | 11 | 138895 | 307 | 64359519 |
COVID-19 | 20.21 | 12.06 | 222 | 138684 | 64918 | 64294908 |
Leukonychia | 20.17 | 12.06 | 6 | 138900 | 30 | 64359796 |
Myelitis transverse | 20.15 | 12.06 | 21 | 138885 | 1602 | 64358224 |
Enterovirus test positive | 20.14 | 12.06 | 10 | 138896 | 230 | 64359596 |
Mental status changes | 20.13 | 12.06 | 66 | 138840 | 61096 | 64298730 |
Human rhinovirus test positive | 20.03 | 12.06 | 12 | 138894 | 404 | 64359422 |
Coronary artery occlusion | 20.02 | 12.06 | 3 | 138903 | 13888 | 64345938 |
Therapeutic response delayed | 20.00 | 12.06 | 16 | 138890 | 866 | 64358960 |
Metastases to muscle | 19.97 | 12.06 | 11 | 138895 | 315 | 64359511 |
Periorbital cellulitis | 19.94 | 12.06 | 15 | 138891 | 741 | 64359085 |
Pyloric stenosis | 19.90 | 12.06 | 12 | 138894 | 409 | 64359417 |
Ageusia | 19.87 | 12.06 | 3 | 138903 | 13810 | 64346016 |
Neuroborreliosis | 19.85 | 12.06 | 8 | 138898 | 110 | 64359716 |
Glycosylated haemoglobin increased | 19.85 | 12.06 | 5 | 138901 | 16014 | 64343812 |
Dry eye | 19.72 | 12.06 | 20 | 138886 | 28999 | 64330827 |
Upper limb fracture | 19.70 | 12.06 | 4 | 138902 | 14862 | 64344964 |
Primary immunodeficiency syndrome | 19.64 | 12.06 | 7 | 138899 | 67 | 64359759 |
Stevens-Johnson syndrome | 19.63 | 12.06 | 27 | 138879 | 34222 | 64325604 |
Sinus disorder | 19.60 | 12.06 | 6 | 138900 | 16902 | 64342924 |
Metastases to pelvis | 19.59 | 12.06 | 13 | 138893 | 525 | 64359301 |
Sputum discoloured | 19.53 | 12.06 | 7 | 138899 | 17849 | 64341977 |
Laboratory test abnormal | 19.51 | 12.06 | 14 | 138892 | 24049 | 64335777 |
Uterine enlargement | 19.50 | 12.06 | 15 | 138891 | 766 | 64359060 |
Pneumonia aspiration | 19.48 | 12.06 | 64 | 138842 | 59207 | 64300619 |
Abdominal mass | 19.42 | 12.06 | 28 | 138878 | 2987 | 64356839 |
Cardiogenic shock | 19.40 | 12.06 | 128 | 138778 | 32299 | 64327527 |
Blood pressure diastolic decreased | 19.39 | 12.06 | 12 | 138894 | 22289 | 64337537 |
Aplastic anaemia | 19.35 | 12.06 | 70 | 138836 | 13850 | 64345976 |
Superior vena cava syndrome | 19.21 | 12.06 | 17 | 138889 | 1058 | 64358768 |
Cerebellar haemangioma | 19.19 | 12.06 | 7 | 138899 | 72 | 64359754 |
Embolism | 19.15 | 12.06 | 64 | 138842 | 12171 | 64347655 |
Amputation stump pain | 19.12 | 12.06 | 6 | 138900 | 37 | 64359789 |
Jejunal stenosis | 19.10 | 12.06 | 7 | 138899 | 73 | 64359753 |
Oral fungal infection | 19.09 | 12.06 | 28 | 138878 | 3033 | 64356793 |
Cerebellar stroke | 19.09 | 12.06 | 12 | 138894 | 441 | 64359385 |
Folliculitis | 19.02 | 12.06 | 22 | 138884 | 30055 | 64329771 |
Sinus polyp | 19.02 | 12.06 | 12 | 138894 | 444 | 64359382 |
Hepatic infarction | 18.95 | 12.06 | 15 | 138891 | 799 | 64359027 |
Splenic candidiasis | 18.94 | 12.06 | 7 | 138899 | 75 | 64359751 |
Sciatica | 18.91 | 12.06 | 10 | 138896 | 20254 | 64339572 |
Movement disorder | 18.91 | 12.06 | 12 | 138894 | 21988 | 64337838 |
Creatinine renal clearance decreased | 18.86 | 12.06 | 4 | 138902 | 14417 | 64345409 |
Transaminases | 18.85 | 12.06 | 7 | 138899 | 76 | 64359750 |
Angina unstable | 18.83 | 12.06 | 5 | 138901 | 15462 | 64344364 |
Hyperbilirubinaemia | 18.82 | 12.06 | 93 | 138813 | 21112 | 64338714 |
Skin laceration | 18.77 | 12.06 | 15 | 138891 | 24402 | 64335424 |
Transplant rejection | 18.73 | 12.06 | 7 | 138899 | 17394 | 64342432 |
Sleep apnoea syndrome | 18.68 | 12.06 | 22 | 138884 | 29810 | 64330016 |
Positron emission tomogram abnormal | 18.62 | 12.06 | 10 | 138896 | 272 | 64359554 |
Vulvovaginitis | 18.55 | 12.06 | 10 | 138896 | 274 | 64359552 |
Cardiac failure acute | 18.48 | 12.06 | 77 | 138829 | 16267 | 64343559 |
Pregnancy | 18.46 | 12.06 | 11 | 138895 | 20854 | 64338972 |
Tissue infiltration | 18.44 | 12.06 | 13 | 138893 | 580 | 64359246 |
Cutaneous T-cell lymphoma | 18.40 | 12.06 | 24 | 138882 | 2328 | 64357498 |
Gastrointestinal inflammation | 18.37 | 12.06 | 41 | 138865 | 6154 | 64353672 |
Enterovirus infection | 18.36 | 12.06 | 19 | 138887 | 1438 | 64358388 |
Neurofibrosarcoma | 18.25 | 12.06 | 9 | 138897 | 204 | 64359622 |
Haemoptysis | 18.25 | 12.06 | 50 | 138856 | 48998 | 64310828 |
Dysaesthesia | 18.25 | 12.06 | 36 | 138870 | 4959 | 64354867 |
Paranasal sinus mucosal hypertrophy | 18.23 | 12.06 | 7 | 138899 | 84 | 64359742 |
Pathogen resistance | 18.22 | 12.06 | 64 | 138842 | 12479 | 64347347 |
Bicytopenia | 18.21 | 12.06 | 30 | 138876 | 3592 | 64356234 |
Liver function test increased | 18.17 | 12.06 | 24 | 138882 | 30946 | 64328880 |
Premature ageing | 18.08 | 12.06 | 7 | 138899 | 86 | 64359740 |
Leukaemia cutis | 18.05 | 12.06 | 8 | 138898 | 141 | 64359685 |
Pulmonary alveolar haemorrhage | 18.05 | 12.06 | 54 | 138852 | 9684 | 64350142 |
Blood glucose decreased | 18.04 | 12.06 | 14 | 138892 | 23109 | 64336717 |
Therapeutic response unexpected | 18.04 | 12.06 | 7 | 138899 | 16994 | 64342832 |
Radiation skin injury | 17.95 | 12.06 | 18 | 138888 | 1312 | 64358514 |
Clostridium test positive | 17.95 | 12.06 | 32 | 138874 | 4083 | 64355743 |
Hypersensitivity pneumonitis | 17.94 | 12.06 | 28 | 138878 | 3204 | 64356622 |
Osteoporosis | 17.92 | 12.06 | 40 | 138866 | 42040 | 64317786 |
Bladder perforation | 17.92 | 12.06 | 10 | 138896 | 294 | 64359532 |
Blood loss anaemia | 17.87 | 12.06 | 4 | 138902 | 13888 | 64345938 |
Chromosome analysis abnormal | 17.82 | 12.06 | 9 | 138897 | 215 | 64359611 |
Hepatosplenomegaly | 17.72 | 12.06 | 37 | 138869 | 5306 | 64354520 |
Hepatic amoebiasis | 17.72 | 12.06 | 7 | 138899 | 91 | 64359735 |
Thrombocytopenia neonatal | 17.71 | 12.06 | 5 | 138901 | 20 | 64359806 |
Basal ganglion degeneration | 17.68 | 12.06 | 11 | 138895 | 397 | 64359429 |
Secondary cerebellar degeneration | 17.67 | 12.06 | 6 | 138900 | 49 | 64359777 |
Pneumonia salmonella | 17.67 | 12.06 | 6 | 138900 | 49 | 64359777 |
Evans syndrome | 17.65 | 12.06 | 11 | 138895 | 398 | 64359428 |
Salivary gland neoplasm | 17.65 | 12.06 | 7 | 138899 | 92 | 64359734 |
Spindle cell sarcoma | 17.63 | 12.06 | 9 | 138897 | 220 | 64359606 |
Disturbance in attention | 17.53 | 12.06 | 39 | 138867 | 41035 | 64318791 |
Gastric pneumatosis | 17.52 | 12.06 | 5 | 138901 | 21 | 64359805 |
Helicobacter sepsis | 17.52 | 12.06 | 5 | 138901 | 21 | 64359805 |
Anger | 17.51 | 12.06 | 6 | 138900 | 15735 | 64344091 |
Pulmonary vein stenosis | 17.50 | 12.06 | 8 | 138898 | 152 | 64359674 |
Pseudocirrhosis | 17.46 | 12.06 | 13 | 138893 | 632 | 64359194 |
Hypertransaminasaemia | 17.44 | 12.06 | 44 | 138862 | 7147 | 64352679 |
Candida endophthalmitis | 17.36 | 12.06 | 8 | 138898 | 155 | 64359671 |
Papillary thyroid cancer | 17.29 | 12.06 | 23 | 138883 | 2275 | 64357551 |
Disseminated cytomegaloviral infection | 17.27 | 12.06 | 11 | 138895 | 414 | 64359412 |
Pulmonary hypoplasia | 17.26 | 12.06 | 6 | 138900 | 53 | 64359773 |
Splenic necrosis | 17.19 | 12.06 | 7 | 138899 | 99 | 64359727 |
Poor venous access | 17.18 | 12.06 | 3 | 138903 | 12414 | 64347412 |
Ocular hyperaemia | 17.18 | 12.06 | 14 | 138892 | 22550 | 64337276 |
Hernia | 17.18 | 12.06 | 4 | 138902 | 13514 | 64346312 |
Acute pulmonary histoplasmosis | 17.16 | 12.06 | 9 | 138897 | 233 | 64359593 |
Splenic marginal zone lymphoma | 17.15 | 12.06 | 5 | 138901 | 23 | 64359803 |
Frequent bowel movements | 17.13 | 12.06 | 9 | 138897 | 18296 | 64341530 |
Toxic neuropathy | 17.12 | 12.06 | 14 | 138892 | 782 | 64359044 |
Radiation necrosis | 17.10 | 12.06 | 10 | 138896 | 322 | 64359504 |
Pharyngeal inflammation | 17.08 | 12.06 | 15 | 138891 | 924 | 64358902 |
Bacterial translocation | 17.08 | 12.06 | 11 | 138895 | 422 | 64359404 |
Sphingomonas paucimobilis infection | 17.06 | 12.06 | 7 | 138899 | 101 | 64359725 |
Rash erythematous | 17.05 | 12.06 | 51 | 138855 | 48582 | 64311244 |
Hypertensive crisis | 17.04 | 12.06 | 9 | 138897 | 18239 | 64341587 |
Diverticulitis | 17.03 | 12.06 | 36 | 138870 | 38582 | 64321244 |
Dysarthria | 16.97 | 12.06 | 68 | 138838 | 59338 | 64300488 |
Synovial sarcoma | 16.97 | 12.06 | 6 | 138900 | 56 | 64359770 |
Urinary retention | 16.96 | 12.06 | 52 | 138854 | 49149 | 64310677 |
Photophobia | 16.94 | 12.06 | 8 | 138898 | 17285 | 64342541 |
Plasma cell myeloma refractory | 16.94 | 12.06 | 7 | 138899 | 103 | 64359723 |
Ventricular dysfunction | 16.91 | 12.06 | 36 | 138870 | 5234 | 64354592 |
Peritonitis viral | 16.87 | 12.06 | 6 | 138900 | 57 | 64359769 |
Hypercholesterolaemia | 16.86 | 12.06 | 6 | 138900 | 15367 | 64344459 |
Abdominal wound dehiscence | 16.85 | 12.06 | 9 | 138897 | 242 | 64359584 |
Chronic hepatitis | 16.82 | 12.06 | 17 | 138889 | 1251 | 64358575 |
Mucosal infection | 16.80 | 12.06 | 11 | 138895 | 434 | 64359392 |
Hepatic fibrosis | 16.76 | 12.06 | 37 | 138869 | 5515 | 64354311 |
Guillain-Barre syndrome | 16.75 | 12.06 | 45 | 138861 | 7590 | 64352236 |
Systolic dysfunction | 16.75 | 12.06 | 27 | 138879 | 3175 | 64356651 |
Campylobacter gastroenteritis | 16.74 | 12.06 | 16 | 138890 | 1100 | 64358726 |
Blood potassium decreased | 16.72 | 12.06 | 39 | 138867 | 40360 | 64319466 |
Miosis | 16.71 | 12.06 | 4 | 138902 | 13262 | 64346564 |
Prescribed underdose | 16.65 | 12.06 | 9 | 138897 | 18006 | 64341820 |
Rotator cuff syndrome | 16.59 | 12.06 | 3 | 138903 | 12104 | 64347722 |
Pulmonary artery stenosis | 16.58 | 12.06 | 7 | 138899 | 109 | 64359717 |
Molluscum contagiosum | 16.52 | 12.06 | 11 | 138895 | 447 | 64359379 |
Squamous cell carcinoma of head and neck | 16.46 | 12.06 | 9 | 138897 | 254 | 64359572 |
Gingivitis ulcerative | 16.46 | 12.06 | 9 | 138897 | 254 | 64359572 |
Streptococcal infection | 16.33 | 12.06 | 44 | 138862 | 7435 | 64352391 |
Dyskinesia | 16.32 | 12.06 | 38 | 138868 | 39350 | 64320476 |
Humoral immune defect | 16.30 | 12.06 | 7 | 138899 | 114 | 64359712 |
Candida pneumonia | 16.28 | 12.06 | 11 | 138895 | 458 | 64359368 |
Blood pressure diastolic abnormal | 16.23 | 12.06 | 3 | 138903 | 11914 | 64347912 |
Ecchymosis | 16.21 | 12.06 | 5 | 138901 | 14017 | 64345809 |
Granulomatous pneumonitis | 16.17 | 12.06 | 6 | 138900 | 65 | 64359761 |
Suspected product quality issue | 16.11 | 12.06 | 9 | 138897 | 265 | 64359561 |
Pneumaturia | 16.05 | 12.06 | 5 | 138901 | 30 | 64359796 |
Spinal stenosis | 16.05 | 12.06 | 5 | 138901 | 13926 | 64345900 |
Opsoclonus myoclonus | 16.04 | 12.06 | 8 | 138898 | 186 | 64359640 |
Human polyomavirus infection | 16.03 | 12.06 | 15 | 138891 | 1004 | 64358822 |
Chronic lymphocytic leukaemia refractory | 16.02 | 12.06 | 7 | 138899 | 119 | 64359707 |
Cerebral aspergillosis | 16.01 | 12.06 | 19 | 138887 | 1674 | 64358152 |
Metastases to abdominal wall | 15.97 | 12.06 | 7 | 138899 | 120 | 64359706 |
Mucoepidermoid carcinoma | 15.93 | 12.06 | 6 | 138900 | 68 | 64359758 |
Epstein-Barr virus associated lymphoproliferative disorder | 15.91 | 12.06 | 26 | 138880 | 3093 | 64356733 |
Haemoglobin abnormal | 15.90 | 12.06 | 38 | 138868 | 5966 | 64353860 |
Wound evisceration | 15.87 | 12.06 | 7 | 138899 | 122 | 64359704 |
Grip strength decreased | 15.86 | 12.06 | 3 | 138903 | 11721 | 64348105 |
Tidal volume decreased | 15.85 | 12.06 | 6 | 138900 | 69 | 64359757 |
Blood calcium decreased | 15.83 | 12.06 | 19 | 138887 | 25535 | 64334291 |
Splenic lesion | 15.83 | 12.06 | 10 | 138896 | 371 | 64359455 |
Myeloproliferative neoplasm | 15.77 | 12.06 | 14 | 138892 | 875 | 64358951 |
Bone marrow necrosis | 15.77 | 12.06 | 8 | 138898 | 193 | 64359633 |
Pneumoperitoneum | 15.77 | 12.06 | 24 | 138882 | 2687 | 64357139 |
Femur fracture | 15.75 | 12.06 | 31 | 138875 | 34104 | 64325722 |
Respiratory rate increased | 15.75 | 12.06 | 10 | 138896 | 18321 | 64341505 |
Lung adenocarcinoma | 15.73 | 12.06 | 41 | 138865 | 6792 | 64353034 |
Extramedullary haemopoiesis | 15.71 | 12.06 | 7 | 138899 | 125 | 64359701 |
BRCA2 gene mutation | 15.70 | 12.06 | 6 | 138900 | 71 | 64359755 |
Primary mediastinal large B-cell lymphoma recurrent | 15.70 | 12.06 | 6 | 138900 | 71 | 64359755 |
Ichthyosis | 15.66 | 12.06 | 7 | 138899 | 126 | 64359700 |
Hepatic infection fungal | 15.66 | 12.06 | 8 | 138898 | 196 | 64359630 |
Metastases to abdominal cavity | 15.62 | 12.06 | 11 | 138895 | 490 | 64359336 |
Hepatitis viral | 15.55 | 12.06 | 14 | 138892 | 891 | 64358935 |
Right ventricular failure | 15.52 | 12.06 | 14 | 138892 | 21457 | 64338369 |
Rectal fissure | 15.50 | 12.06 | 13 | 138893 | 752 | 64359074 |
Fusarium infection | 15.49 | 12.06 | 18 | 138888 | 1551 | 64358275 |
Lymphadenopathy mediastinal | 15.46 | 12.06 | 29 | 138877 | 3847 | 64355979 |
Platelet count abnormal | 15.46 | 12.06 | 30 | 138876 | 4082 | 64355744 |
Joint ankylosis | 15.44 | 12.06 | 13 | 138893 | 756 | 64359070 |
Drug level decreased | 15.44 | 12.06 | 3 | 138903 | 11500 | 64348326 |
Omental infarction | 15.43 | 12.06 | 3 | 138903 | 0 | 64359826 |
Meningoencephalitis viral | 15.40 | 12.06 | 10 | 138896 | 389 | 64359437 |
Poor quality sleep | 15.39 | 12.06 | 11 | 138895 | 18940 | 64340886 |
Glaucoma | 15.36 | 12.06 | 8 | 138898 | 16340 | 64343486 |
Sinus congestion | 15.35 | 12.06 | 7 | 138899 | 15432 | 64344394 |
Adenocarcinoma gastric | 15.25 | 12.06 | 18 | 138888 | 1577 | 64358249 |
Acanthosis | 15.24 | 12.06 | 10 | 138896 | 396 | 64359430 |
Morphoea | 15.24 | 12.06 | 10 | 138896 | 396 | 64359430 |
Joint effusion | 15.23 | 12.06 | 5 | 138901 | 13468 | 64346358 |
Scedosporium infection | 15.17 | 12.06 | 16 | 138890 | 1238 | 64358588 |
Adenovirus infection | 15.16 | 12.06 | 42 | 138864 | 7213 | 64352613 |
Mydriasis | 15.13 | 12.06 | 7 | 138899 | 15305 | 64344521 |
Cancer fatigue | 15.12 | 12.06 | 6 | 138900 | 79 | 64359747 |
Scar | 15.09 | 12.06 | 5 | 138901 | 13393 | 64346433 |
Fracture | 15.09 | 12.06 | 11 | 138895 | 18744 | 64341082 |
Metapneumovirus bronchiolitis | 15.05 | 12.06 | 4 | 138902 | 12 | 64359814 |
Failure to thrive | 15.04 | 12.06 | 53 | 138853 | 10351 | 64349475 |
Acute lymphocytic leukaemia refractory | 15.04 | 12.06 | 7 | 138899 | 139 | 64359687 |
Right ventricular dysfunction | 14.98 | 12.06 | 21 | 138885 | 2182 | 64357644 |
Inflammation | 14.96 | 12.06 | 81 | 138825 | 65219 | 64294607 |
Product storage error | 14.95 | 12.06 | 5 | 138901 | 13313 | 64346513 |
Torulopsis infection | 14.92 | 12.06 | 5 | 138901 | 39 | 64359787 |
Scrotal abscess | 14.91 | 12.06 | 10 | 138896 | 411 | 64359415 |
Azoospermia | 14.90 | 12.06 | 7 | 138899 | 142 | 64359684 |
Chromaturia | 14.89 | 12.06 | 16 | 138890 | 22595 | 64337231 |
Metastases to eye | 14.88 | 12.06 | 8 | 138898 | 218 | 64359608 |
Angioimmunoblastic T-cell lymphoma | 14.87 | 12.06 | 10 | 138896 | 413 | 64359413 |
Chest discomfort | 14.87 | 12.06 | 169 | 138737 | 115937 | 64243889 |
Necrosis | 14.85 | 12.06 | 45 | 138861 | 8126 | 64351700 |
Lewis-Sumner syndrome | 14.81 | 12.06 | 5 | 138901 | 40 | 64359786 |
Mood altered | 14.74 | 12.06 | 8 | 138898 | 15971 | 64343855 |
Pulmonary sarcoidosis | 14.70 | 12.06 | 15 | 138891 | 1116 | 64358710 |
Abdominal distension | 14.65 | 12.06 | 134 | 138772 | 95860 | 64263966 |
Sudden death | 14.65 | 12.06 | 13 | 138893 | 20083 | 64339743 |
Ventricular internal diameter abnormal | 14.64 | 12.06 | 7 | 138899 | 148 | 64359678 |
Oligohydramnios | 14.54 | 12.06 | 25 | 138881 | 3099 | 64356727 |
Deafness | 14.54 | 12.06 | 78 | 138828 | 18281 | 64341545 |
Triple negative breast cancer | 14.54 | 12.06 | 6 | 138900 | 88 | 64359738 |
Heavy menstrual bleeding | 14.52 | 12.06 | 4 | 138902 | 12073 | 64347753 |
Atypical haemolytic uraemic syndrome | 14.52 | 12.06 | 12 | 138894 | 680 | 64359146 |
Pleural neoplasm | 14.46 | 12.06 | 8 | 138898 | 231 | 64359595 |
Deafness bilateral | 14.46 | 12.06 | 19 | 138887 | 1857 | 64357969 |
Secretion discharge | 14.32 | 12.06 | 4 | 138902 | 11960 | 64347866 |
Performance status decreased | 14.26 | 12.06 | 34 | 138872 | 5330 | 64354496 |
Respiratory tract infection | 14.25 | 12.06 | 133 | 138773 | 37274 | 64322552 |
Large intestine polyp | 14.19 | 12.06 | 3 | 138903 | 10834 | 64348992 |
Lymph node pain | 14.17 | 12.06 | 16 | 138890 | 1336 | 64358490 |
Beta 2 microglobulin decreased | 14.17 | 12.06 | 4 | 138902 | 16 | 64359810 |
Noctiphobia | 14.17 | 12.06 | 4 | 138902 | 16 | 64359810 |
Cryptococcal fungaemia | 14.14 | 12.06 | 7 | 138899 | 160 | 64359666 |
Head discomfort | 14.08 | 12.06 | 4 | 138902 | 11830 | 64347996 |
Osteopenia | 14.02 | 12.06 | 8 | 138898 | 15532 | 64344294 |
Metastases to vagina | 13.98 | 12.06 | 4 | 138902 | 17 | 64359809 |
Synovial sarcoma metastatic | 13.98 | 12.06 | 4 | 138902 | 17 | 64359809 |
Delusion | 13.93 | 12.06 | 11 | 138895 | 18003 | 64341823 |
Pneumonitis chemical | 13.91 | 12.06 | 9 | 138897 | 348 | 64359478 |
Enterocolitis | 13.89 | 12.06 | 57 | 138849 | 11961 | 64347865 |
Disseminated cryptococcosis | 13.86 | 12.06 | 17 | 138889 | 1550 | 64358276 |
Device issue | 13.86 | 12.06 | 17 | 138889 | 22631 | 64337195 |
Metastatic neoplasm | 13.86 | 12.06 | 30 | 138876 | 4412 | 64355414 |
Hypothalamo-pituitary disorder | 13.85 | 12.06 | 14 | 138892 | 1030 | 64358796 |
Invasive breast carcinoma | 13.84 | 12.06 | 10 | 138896 | 464 | 64359362 |
Small intestinal perforation | 13.83 | 12.06 | 22 | 138884 | 2558 | 64357268 |
Musculoskeletal discomfort | 13.82 | 12.06 | 9 | 138897 | 16268 | 64343558 |
Restless legs syndrome | 13.82 | 12.06 | 10 | 138896 | 17106 | 64342720 |
Osteolysis | 13.80 | 12.06 | 23 | 138883 | 2780 | 64357046 |
Deep vein thrombosis | 13.80 | 12.06 | 310 | 138596 | 104872 | 64254954 |
Metastases to ovary | 13.78 | 12.06 | 8 | 138898 | 254 | 64359572 |
Hyperviscosity syndrome | 13.77 | 12.06 | 9 | 138897 | 354 | 64359472 |
Peripheral coldness | 13.75 | 12.06 | 6 | 138900 | 13578 | 64346248 |
Encephalitis viral | 13.74 | 12.06 | 21 | 138885 | 2359 | 64357467 |
Granulomatous liver disease | 13.74 | 12.06 | 15 | 138891 | 1207 | 64358619 |
Rib fracture | 13.73 | 12.06 | 19 | 138887 | 24019 | 64335807 |
Dyspepsia | 13.65 | 12.06 | 109 | 138797 | 80203 | 64279623 |
Melaena | 13.65 | 12.06 | 64 | 138842 | 53484 | 64306342 |
Acute leukaemia | 13.60 | 12.06 | 17 | 138889 | 1581 | 64358245 |
Streptococcal bacteraemia | 13.57 | 12.06 | 24 | 138882 | 3043 | 64356783 |
Metastases to pancreas | 13.53 | 12.06 | 10 | 138896 | 481 | 64359345 |
Klebsiella sepsis | 13.51 | 12.06 | 22 | 138884 | 2610 | 64357216 |
Impaired work ability | 13.50 | 12.06 | 8 | 138898 | 15211 | 64344615 |
Muscular weakness | 13.46 | 12.06 | 193 | 138713 | 127145 | 64232681 |
Malignant neoplasm of orbit | 13.45 | 12.06 | 4 | 138902 | 20 | 64359806 |
Vascular compression | 13.39 | 12.06 | 8 | 138898 | 268 | 64359558 |
Hypoglossal nerve paresis | 13.37 | 12.06 | 6 | 138900 | 109 | 64359717 |
Herpes simplex reactivation | 13.37 | 12.06 | 8 | 138898 | 269 | 64359557 |
Endothelial dysfunction | 13.36 | 12.06 | 7 | 138899 | 181 | 64359645 |
Increased liver stiffness | 13.36 | 12.06 | 3 | 138903 | 3 | 64359823 |
Eating disorder | 13.33 | 12.06 | 10 | 138896 | 16795 | 64343031 |
Dermatitis allergic | 13.32 | 12.06 | 8 | 138898 | 15101 | 64344725 |
Hyperlipidaemia | 13.28 | 12.06 | 18 | 138888 | 22958 | 64336868 |
Herpes zoster | 13.25 | 12.06 | 242 | 138664 | 78945 | 64280881 |
Rash macular | 13.25 | 12.06 | 19 | 138887 | 23666 | 64336160 |
Hypophagia | 13.25 | 12.06 | 137 | 138769 | 39450 | 64320376 |
Metastases to uterus | 13.25 | 12.06 | 5 | 138901 | 57 | 64359769 |
Urethritis | 13.22 | 12.06 | 10 | 138896 | 498 | 64359328 |
Extravasation blood | 13.21 | 12.06 | 9 | 138897 | 380 | 64359446 |
Anaphylactic reaction | 13.20 | 12.06 | 90 | 138816 | 68574 | 64291252 |
Cyanosis | 13.17 | 12.06 | 17 | 138889 | 22138 | 64337688 |
Adenoviral haemorrhagic cystitis | 13.17 | 12.06 | 10 | 138896 | 501 | 64359325 |
Eye irritation | 13.15 | 12.06 | 9 | 138897 | 15847 | 64343979 |
Hypercalcaemia | 13.14 | 12.06 | 114 | 138792 | 31302 | 64328524 |
Mediastinal fibrosis | 13.13 | 12.06 | 4 | 138902 | 22 | 64359804 |
Cryptosporidiosis infection | 13.12 | 12.06 | 11 | 138895 | 636 | 64359190 |
Post procedural complication | 13.10 | 12.06 | 16 | 138890 | 21337 | 64338489 |
H1N1 influenza | 13.09 | 12.06 | 20 | 138886 | 2246 | 64357580 |
Lymphoedema | 13.08 | 12.06 | 49 | 138857 | 9856 | 64349970 |
Non-cirrhotic portal hypertension | 13.08 | 12.06 | 9 | 138897 | 386 | 64359440 |
Hip deformity | 13.08 | 12.06 | 7 | 138899 | 189 | 64359637 |
Pseudomonal bacteraemia | 13.07 | 12.06 | 20 | 138886 | 2249 | 64357577 |
Blood culture positive | 13.07 | 12.06 | 42 | 138864 | 7826 | 64352000 |
Mediastinal mass | 13.07 | 12.06 | 10 | 138896 | 507 | 64359319 |
Mitral valve incompetence | 13.04 | 12.06 | 97 | 138809 | 25441 | 64334385 |
Systemic inflammatory response syndrome | 13.00 | 12.06 | 50 | 138856 | 10185 | 64349641 |
Facial paresis | 12.99 | 12.06 | 31 | 138875 | 4861 | 64354965 |
Intervertebral disc degeneration | 12.96 | 12.06 | 6 | 138900 | 13114 | 64346712 |
PIK3CA-activated mutation | 12.93 | 12.06 | 10 | 138896 | 515 | 64359311 |
Empyema | 12.89 | 12.06 | 26 | 138880 | 3639 | 64356187 |
Blood triglycerides increased | 12.82 | 12.06 | 13 | 138893 | 18853 | 64340973 |
Stomatitis necrotising | 12.82 | 12.06 | 7 | 138899 | 197 | 64359629 |
Dystonia | 12.82 | 12.06 | 13 | 138893 | 18852 | 64340974 |
Metastases to the mediastinum | 12.78 | 12.06 | 10 | 138896 | 524 | 64359302 |
Mantle cell lymphoma | 12.75 | 12.06 | 14 | 138892 | 1134 | 64358692 |
Tuberculosis liver | 12.73 | 12.06 | 5 | 138901 | 64 | 64359762 |
Systemic mycosis | 12.72 | 12.06 | 20 | 138886 | 2303 | 64357523 |
Infected neoplasm | 12.70 | 12.06 | 8 | 138898 | 295 | 64359531 |
Dysplasia | 12.69 | 12.06 | 14 | 138892 | 1140 | 64358686 |
Minimal residual disease | 12.64 | 12.06 | 9 | 138897 | 408 | 64359418 |
Angina pectoris | 12.63 | 12.06 | 52 | 138854 | 45029 | 64314797 |
Wrist fracture | 12.63 | 12.06 | 3 | 138903 | 9998 | 64349828 |
Blindness | 12.62 | 12.06 | 86 | 138820 | 21933 | 64337893 |
Anaesthesia | 12.60 | 12.06 | 9 | 138897 | 410 | 64359416 |
Procedural pneumothorax | 12.59 | 12.06 | 5 | 138901 | 66 | 64359760 |
Drug eruption | 12.59 | 12.06 | 38 | 138868 | 36098 | 64323728 |
Obstructive airways disorder | 12.58 | 12.06 | 19 | 138887 | 23166 | 64336660 |
Listeria encephalitis | 12.56 | 12.06 | 8 | 138898 | 301 | 64359525 |
Splenic infarction | 12.54 | 12.06 | 24 | 138882 | 3233 | 64356593 |
Bone density decreased | 12.54 | 12.06 | 3 | 138903 | 9949 | 64349877 |
Paraplegia | 12.52 | 12.06 | 29 | 138877 | 4461 | 64355365 |
Vessel puncture site bruise | 12.51 | 12.06 | 9 | 138897 | 415 | 64359411 |
Tooth fracture | 12.49 | 12.06 | 3 | 138903 | 9924 | 64349902 |
Liver abscess | 12.48 | 12.06 | 32 | 138874 | 5248 | 64354578 |
T-cell lymphoma recurrent | 12.46 | 12.06 | 5 | 138901 | 68 | 64359758 |
Neutrophilic dermatosis | 12.44 | 12.06 | 10 | 138896 | 545 | 64359281 |
Large intestine perforation | 12.44 | 12.06 | 57 | 138849 | 12547 | 64347279 |
Cardiac failure congestive | 12.41 | 12.06 | 202 | 138704 | 130378 | 64229448 |
Vaginal haemorrhage | 12.40 | 12.06 | 14 | 138892 | 19330 | 64340496 |
Paresis | 12.35 | 12.06 | 25 | 138881 | 3507 | 64356319 |
Diabetes mellitus | 12.35 | 12.06 | 88 | 138818 | 66386 | 64293440 |
Tenosynovitis | 12.34 | 12.06 | 5 | 138901 | 11828 | 64347998 |
Oral candidiasis | 12.33 | 12.06 | 89 | 138817 | 23123 | 64336703 |
Ear pain | 12.33 | 12.06 | 22 | 138884 | 25114 | 64334712 |
Acute hepatitis C | 12.32 | 12.06 | 7 | 138899 | 213 | 64359613 |
Product intolerance | 12.31 | 12.06 | 4 | 138902 | 28 | 64359798 |
Ligament sprain | 12.31 | 12.06 | 4 | 138902 | 10848 | 64348978 |
Adult T-cell lymphoma/leukaemia | 12.30 | 12.06 | 8 | 138898 | 312 | 64359514 |
Central nervous system infection | 12.30 | 12.06 | 14 | 138892 | 1180 | 64358646 |
Feeling cold | 12.28 | 12.06 | 20 | 138886 | 23658 | 64336168 |
B-lymphocyte count abnormal | 12.26 | 12.06 | 5 | 138901 | 71 | 64359755 |
Mental disorder | 12.22 | 12.06 | 24 | 138882 | 26421 | 64333405 |
Adenocarcinoma of appendix | 12.20 | 12.06 | 5 | 138901 | 72 | 64359754 |
Incorrect product administration duration | 12.18 | 12.06 | 3 | 138903 | 9755 | 64350071 |
Seasonal allergy | 12.16 | 12.06 | 5 | 138901 | 11721 | 64348105 |
Gout | 12.15 | 12.06 | 17 | 138889 | 21396 | 64338430 |
Extraskeletal myxoid chondrosarcoma | 12.15 | 12.06 | 3 | 138903 | 6 | 64359820 |
Acute myocardial infarction | 12.14 | 12.06 | 94 | 138812 | 69624 | 64290202 |
Parkinsonism | 12.13 | 12.06 | 8 | 138898 | 14365 | 64345461 |
Malignant ascites | 12.12 | 12.06 | 13 | 138893 | 1025 | 64358801 |
Device use error | 12.10 | 12.06 | 36 | 138870 | 6435 | 64353391 |
Cancer in remission | 12.08 | 12.06 | 4 | 138902 | 30 | 64359796 |
Selective mutism | 12.07 | 12.06 | 5 | 138901 | 74 | 64359752 |
Hip arthroplasty | 12.07 | 12.06 | 17 | 138889 | 21334 | 64338492 |
None
Source | Code | Description |
---|---|---|
ATC | L01DB01 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS ANTINEOPLASTIC AGENTS CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES Anthracyclines and related substances |
FDA CS | M0028312 | Anthracyclines |
FDA MoA | N0000000176 | Topoisomerase Inhibitors |
FDA EPC | N0000175414 | Anthracycline Topoisomerase Inhibitor |
MeSH PA | D000903 | Antibiotics, Antineoplastic |
MeSH PA | D000970 | Antineoplastic Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D059005 | Topoisomerase II Inhibitors |
CHEBI has role | CHEBI:76971 | Escherichia coli metabolites |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Acute lymphoid leukemia | indication | 91857003 | DOID:9952 |
Acute myeloid leukemia, disease | indication | 91861009 | |
Kaposi's sarcoma | indication | 109385007 | |
Diffuse non-Hodgkin's lymphoma, large cell | indication | 109969005 | |
Multiple myeloma | indication | 109989006 | DOID:9538 |
Hodgkin's disease | indication | 118599009 | |
Non-Hodgkin's lymphoma | indication | 118601006 | |
Burkitt's lymphoma | indication | 118617000 | |
Small cell carcinoma of lung | indication | 254632001 | DOID:5409 |
Carcinoma of breast | indication | 254838004 | DOID:3459 |
Nephroblastoma | indication | 302849000 | DOID:2154 |
Osteosarcoma of bone | indication | 307576001 | DOID:3376 |
Follicular non-Hodgkin's lymphoma | indication | 308121000 | |
Malignant tumor of lung | indication | 363358000 | |
Malignant tumor of ovary | indication | 363443007 | DOID:2394 |
Malignant tumor of thyroid gland | indication | 363478007 | DOID:1781 |
Kaposi's sarcoma associated with AIDS | indication | 420524008 | |
Neuroblastoma | indication | 432328008 | DOID:769 |
Carcinoma of female breast | indication | 447782002 | |
Soft or Connective Tissue Sarcoma | indication | ||
Invasive Bladder Malignancy | indication | ||
Metastatic Breast Carcinoma | indication | ||
Metastatic Gastric Cancer | indication | ||
Carcinoid syndrome | off-label use | 35868009 | |
Ewing's sarcoma | off-label use | 76909002 | DOID:3369 |
Chronic lymphoid leukemia, disease | off-label use | 92814006 | |
Malignant neoplasm of liver | off-label use | 93870000 | DOID:3571 |
Endometrial carcinoma | off-label use | 254878006 | DOID:2871 |
Malignant tumor of head and/or neck | off-label use | 255056009 | |
Primary cutaneous T-cell lymphoma | off-label use | 400122007 | |
Adenocarcinoma of pancreas | off-label use | 700423003 | DOID:4074 |
Pancreatic Neuroendocrine Tumor | off-label use | 717919005 | |
Mycosis | contraindication | 3218000 | DOID:1564 |
Bundle branch block | contraindication | 6374002 | |
Hyperbilirubinemia | contraindication | 14783006 | DOID:2741 |
Viral disease | contraindication | 34014006 | DOID:934 |
Hyperuricemia | contraindication | 35885006 | DOID:1920 |
Conduction disorder of the heart | contraindication | 44808001 | |
Myocarditis | contraindication | 50920009 | DOID:820 |
Heart disease | contraindication | 56265001 | DOID:114 |
Hepatic failure | contraindication | 59927004 | |
Heart failure | contraindication | 84114007 | DOID:6000 |
Leukopenia | contraindication | 84828003 | DOID:615 |
Cardiomyopathy | contraindication | 85898001 | DOID:0050700 |
Bacterial infectious disease | contraindication | 87628006 | |
Anemia due to enzyme deficiency | contraindication | 111577008 | |
Deficiency of glucose-6-phosphate dehydrogenase | contraindication | 124134002 | DOID:2862 |
Atrioventricular block | contraindication | 233917008 | DOID:0050820 |
Disease of liver | contraindication | 235856003 | DOID:409 |
Anemia | contraindication | 271737000 | DOID:2355 |
Pregnancy, function | contraindication | 289908002 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Neutropenic disorder | contraindication | 303011007 | DOID:1227 |
Bone marrow depression | contraindication | 307762000 | |
Breastfeeding (mother) | contraindication | 413712001 | |
Myocardial infarction in recovery phase | contraindication | 418044006 | |
Asymptomatic left ventricular systolic dysfunction | contraindication | 698592004 | |
Protozoal Infection | contraindication | ||
Severe Cardiac Disease | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 7.85 | acidic |
pKa2 | 9.21 | acidic |
pKa3 | 9.92 | acidic |
pKa4 | 11.11 | acidic |
pKa5 | 8.6 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2-alpha | Enzyme | INHIBITOR | IC50 | 6 | CHEMBL | CHEMBL | |||
Multidrug resistance protein 1 | Transporter | IC50 | 4.01 | CHEMBL | |||||
Muscarinic acetylcholine receptor M1 | GPCR | Ki | 5.43 | DRUG MATRIX | |||||
Canalicular multispecific organic anion transporter 1 | Transporter | WOMBAT-PK | |||||||
Multidrug resistance-associated protein 1 | Transporter | WOMBAT-PK | |||||||
ATP-binding cassette sub-family G member 2 | Transporter | WOMBAT-PK | |||||||
Multidrug resistance-associated protein 6 | Transporter | WOMBAT-PK | |||||||
Caspase-1 | Enzyme | IC50 | 4.91 | DRUG MATRIX | |||||
Tyrosine-protein kinase Lck | Kinase | IC50 | 4.50 | DRUG MATRIX | |||||
Tyrosine-protein kinase Fyn | Kinase | IC50 | 5.29 | DRUG MATRIX | |||||
Receptor tyrosine-protein kinase erbB-2 | Kinase | IC50 | 5.61 | DRUG MATRIX | |||||
72 kDa type IV collagenase | Enzyme | IC50 | 5.96 | CHEMBL | |||||
DNA topoisomerase 1 | Enzyme | IC50 | 4.70 | CHEMBL | |||||
Telomerase reverse transcriptase | Enzyme | IC50 | 4.14 | CHEMBL | |||||
DNA topoisomerase 2-beta | Enzyme | IC50 | 5.46 | CHEMBL | |||||
Aurora kinase A | Kinase | IC50 | 7.40 | CHEMBL | |||||
CDGSH iron-sulfur domain-containing protein 1 | Unclassified | Ki | 5.46 | CHEMBL | |||||
Ribonuclease pancreatic | Enzyme | IC50 | 4.60 | CHEMBL | |||||
Arachidonate 15-lipoxygenase | Enzyme | IC50 | 4.87 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 1B | GPCR | Ki | 4.81 | DRUG MATRIX | |||||
Integrase | Enzyme | IC50 | 6.05 | CHEMBL | |||||
Reverse transcriptase/RNaseH | Enzyme | IC50 | 4.28 | CHEMBL | |||||
Reverse transcriptase | Enzyme | IC50 | 4.28 | CHEMBL | |||||
Type-2 restriction enzyme HindIII | Unclassified | IC50 | 4.02 | CHEMBL | |||||
Type-2 restriction enzyme ScaI | Unclassified | IC50 | 4.60 | CHEMBL | |||||
ORF 73 | Unclassified | AC50 | 5.84 | CHEMBL | |||||
UDP-galactopyranose mutase | Enzyme | AC50 | 4.49 | CHEMBL | |||||
5-hydroxytryptamine receptor 4 | GPCR | Ki | 5.68 | DRUG MATRIX | |||||
DNA | Enzyme | IC50 | 5.52 | CHEMBL |
ID | Source |
---|---|
4019737 | VUID |
N0000147829 | NUI |
D01275 | KEGG_DRUG |
25316-40-9 | SECONDARY_CAS_RN |
4018106 | VANDF |
4019737 | VANDF |
C0013089 | UMLSCUI |
CHEBI:28748 | CHEBI |
DM2 | PDB_CHEM_ID |
CHEMBL53463 | ChEMBL_ID |
CHEMBL359744 | ChEMBL_ID |
D004317 | MESH_DESCRIPTOR_UI |
DB00997 | DRUGBANK_ID |
C506643 | MESH_SUPPLEMENTAL_RECORD_UI |
7069 | IUPHAR_LIGAND_ID |
3005 | INN_ID |
80168379AG | UNII |
31703 | PUBCHEM_CID |
142433 | RXNORM |
3368 | MMSL |
4639 | MMSL |
47543 | MMSL |
47549 | MMSL |
d00218 | MMSL |
d04004 | MMSL |
002659 | NDDF |
004818 | NDDF |
372817009 | SNOMEDCT_US |
428681007 | SNOMEDCT_US |
68444001 | SNOMEDCT_US |
90875009 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-3030 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 34 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-3031 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 34 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-3032 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 34 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-3033 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 34 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-3034 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 34 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-4004 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 33 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-4015 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 33 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-4026 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 33 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-4037 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | NDA | 33 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9084 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9085 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9086 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9087 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9088 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9089 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9090 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9091 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9092 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Doxorubicin Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9093 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 2 mg | INTRAVENOUS | ANDA | 27 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9275 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9277 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9369 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9370 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9371 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9372 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9546 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9547 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9548 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
Adriamycin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9549 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 26 sections |
DOXIL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0063 | INJECTION, SUSPENSION, LIPOSOMAL | 2 mg | INTRAVENOUS | NDA | 26 sections |