dioxyline 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
911 147-27-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dioxyline phosphate
  • dimoxyline
  • dioxyline
  • paveril
  • Molecular weight: 367.45
  • Formula: C22H25NO4
  • CLOGP: 4.61
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 0
  • TPSA: 49.81
  • ALOGS: -4.65
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.0 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Methionine aminopeptidase 2 Enzyme IC50 4.46 CHEMBL
Methionine aminopeptidase 1 Enzyme IC50 4.37 CHEMBL

External reference:

IDSource
CHEBI:135548 CHEBI
CHEMBL1170610 ChEMBL_ID
CHEMBL2108950 ChEMBL_ID
CHEMBL2105041 ChEMBL_ID
C004856 MESH_SUPPLEMENTAL_RECORD_UI
000695 NDDF
28464005 SNOMEDCT_US
412174005 SNOMEDCT_US
C0602100 UMLSCUI
208 INN_ID
21877 PUBCHEM_CID
46X4C9TILS UNII

Pharmaceutical products:

None