dimenhydrinate ๐Ÿถ Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
N-methylated xanthine derivatives 901 523-87-5

Description:

MoleculeDescription

Synonyms:

  • dimenhydrinate
  • andramine
  • chloranautine
  • diamarin
  • diphenhydramine 8-chlorotheophyllinate
  • diphenhydrinate
  • dramamine
  • menhydrinate
  • theohydramine
A drug combination that contains diphenhydramine and theophylline. It is used for treating VERTIGO, MOTION SICKNESS, and NAUSEA associated with PREGNANCY.
  • Molecular weight: 469.97
  • Formula: C24H28ClN5O3
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
May 31, 1972 FDA ALRA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Urine abnormality 411.55 15.04 157 34934 6081 50563952
Lymphocyte count decreased 319.43 15.04 209 34882 26098 50543935
Urine leukocyte esterase positive 266.23 15.04 93 34998 2790 50567243
White blood cells urine positive 201.00 15.04 86 35005 4492 50565541
Blood urine present 198.66 15.04 119 34972 12714 50557319
Red blood cells urine positive 194.42 15.04 73 35018 2702 50567331
Enthesopathy 181.26 15.04 92 34999 7101 50562932
Urinary sediment present 163.97 15.04 59 35032 1932 50568101
Tongue disorder 159.86 15.04 92 34999 9124 50560909
Blood parathyroid hormone decreased 156.32 15.04 83 35008 7031 50563002
Urine ketone body present 151.27 15.04 58 35033 2275 50567758
Tenosynovitis 148.22 15.04 92 34999 10473 50559560
Red blood cell sedimentation rate 143.17 15.04 63 35028 3523 50566510
Panniculitis 142.48 15.04 83 35008 8420 50561613
Flushing 130.02 15.04 194 34897 66821 50503212
Granuloma skin 128.17 15.04 68 35023 5750 50564283
Skin necrosis 126.16 15.04 84 35007 10783 50559250
Urine analysis abnormal 125.48 15.04 61 35030 4289 50565744
Crystal urine present 122.59 15.04 44 35047 1430 50568603
Red cell distribution width increased 118.72 15.04 74 35017 8485 50561548
Rheumatoid nodule 116.39 15.04 85 35006 12650 50557383
Aplastic anaemia 110.39 15.04 68 35023 7635 50562398
Haemoglobin urine present 106.25 15.04 34 35057 772 50569261
Death 105.35 15.04 47 35044 325332 50244701
Chest discomfort 104.35 15.04 211 34880 92511 50477522
Culture urine positive 101.37 15.04 49 35042 3402 50566631
Alanine aminotransferase abnormal 101.34 15.04 52 35039 4104 50565929
Ulcer 100.96 15.04 95 34996 20105 50549928
Bacterial test positive 97.86 15.04 53 35038 4670 50565363
Tendonitis 92.10 15.04 83 35008 16622 50553411
Neovascularisation 90.92 15.04 32 35059 981 50569052
Eosinophil count increased 87.70 15.04 62 35029 8768 50561265
Fear of injection 85.23 15.04 53 35038 6050 50563983
Lymphocyte percentage decreased 80.50 15.04 39 35052 2721 50567312
Bacterial test 79.46 15.04 30 35061 1127 50568906
Hypercalcaemia 78.93 15.04 89 35002 23263 50546770
Specific gravity urine decreased 78.48 15.04 26 35065 661 50569372
Feeling hot 76.72 15.04 114 34977 39088 50530945
C-reactive protein abnormal 71.11 15.04 92 34999 27717 50542316
Eosinophil percentage increased 70.02 15.04 26 35065 932 50569101
Neutrophil percentage increased 69.05 15.04 35 35056 2692 50567341
Nausea 67.37 15.04 765 34326 704633 49865400
Basal cell carcinoma 67.26 15.04 82 35009 23274 50546759
Drug eruption 64.95 15.04 81 35010 23525 50546508
Monocyte percentage increased 64.35 15.04 25 35066 1016 50569017
Mean cell haemoglobin concentration increased 62.75 15.04 20 35071 448 50569585
Insomnia 62.17 15.04 263 34828 174602 50395431
Infusion site pain 61.56 15.04 58 35033 12288 50557745
Blood creatinine decreased 61.48 15.04 40 35051 4936 50565097
Rash pruritic 59.98 15.04 114 34977 47732 50522301
Urticaria 59.21 15.04 211 34880 129350 50440683
Gangrene 58.67 15.04 38 35053 4654 50565379
Arterial occlusive disease 57.82 15.04 38 35053 4770 50565263
Alveolitis 56.89 15.04 30 35061 2504 50567529
Monocyte count decreased 56.06 15.04 27 35064 1859 50568174
Loss of personal independence in daily activities 55.83 15.04 139 34952 69911 50500122
Body temperature increased 55.47 15.04 87 35004 31254 50538779
Blood uric acid decreased 55.37 15.04 20 35071 662 50569371
Paradoxical drug reaction 54.31 15.04 33 35058 3614 50566419
Poor venous access 54.30 15.04 50 35041 10290 50559743
Completed suicide 53.18 15.04 13 35078 131876 50438157
Red cell distribution width decreased 52.63 15.04 22 35069 1083 50568950
Oropharyngeal pain 51.44 15.04 144 34947 77657 50492376
Alanine aminotransferase increased 51.19 15.04 156 34935 88203 50481830
Oesophageal spasm 51.03 15.04 27 35064 2269 50567764
Heart rate increased 50.11 15.04 142 34949 77108 50492925
Intestinal pseudo-obstruction 49.79 15.04 19 35072 735 50569298
Blood thyroid stimulating hormone increased 49.72 15.04 38 35053 6054 50563979
Blood pressure fluctuation 49.48 15.04 89 35002 35734 50534299
Headache 49.37 15.04 552 34539 505983 50064050
Gastric disorder 48.15 15.04 79 35012 29469 50540564
Drug ineffective 47.82 15.04 353 34738 818980 49751053
Product dose omission issue 47.36 15.04 35 35056 183803 50386230
Protein urine present 47.12 15.04 35 35056 5342 50564691
Mean cell haemoglobin decreased 46.76 15.04 29 35062 3294 50566739
Red blood cell sedimentation rate increased 45.73 15.04 77 35014 29339 50540694
Heart sounds 45.68 15.04 17 35074 613 50569420
Toxicity to various agents 45.66 15.04 48 35043 212451 50357582
Wound 45.54 15.04 9 35082 105785 50464248
Skin ulcer 45.31 15.04 85 35006 35233 50534800
Haematocrit decreased 44.65 15.04 84 35007 34892 50535141
Neutrophil count increased 44.42 15.04 52 35039 14143 50555890
Prolonged expiration 43.45 15.04 17 35074 704 50569329
Creatinine urine decreased 43.25 15.04 12 35079 163 50569870
Red blood cell count decreased 42.87 15.04 81 35010 33754 50536279
Nitrite urine present 42.63 15.04 18 35073 909 50569124
Erythema 42.15 15.04 207 34884 146207 50423826
Joint injury 42.10 15.04 63 35028 21726 50548307
Arteriovenous fistula occlusion 41.92 15.04 14 35077 365 50569668
Hyponatraemia 41.75 15.04 8 35083 96131 50473902
pH urine increased 41.60 15.04 14 35077 374 50569659
Body temperature decreased 41.53 15.04 54 35037 16341 50553692
Acute kidney injury 41.11 15.04 59 35032 227999 50342034
Blue toe syndrome 40.98 15.04 14 35077 392 50569641
Drug interaction 40.77 15.04 47 35044 199574 50370459
Swelling 40.27 15.04 48 35043 200824 50369209
Confusional state 39.93 15.04 42 35049 185886 50384147
Cardiac failure congestive 38.89 15.04 6 35085 84376 50485657
Oesophageal pain 38.28 15.04 24 35067 2778 50567255
Red blood cells urine 37.78 15.04 14 35077 499 50569534
Blood pressure increased 37.44 15.04 187 34904 132945 50437088
Leukocyturia 37.40 15.04 17 35074 1026 50569007
Urine leukocyte esterase 36.96 15.04 10 35081 123 50569910
Specific gravity urine increased 36.72 15.04 11 35080 199 50569834
C-reactive protein increased 36.30 15.04 115 34976 66359 50503674
Heart rate decreased 36.28 15.04 79 35012 36418 50533615
Blood thyroid stimulating hormone decreased 36.21 15.04 27 35064 4145 50565888
Multiple sclerosis relapse 36.07 15.04 87 35004 42877 50527156
Stress 35.97 15.04 100 34991 53693 50516340
Thrombocytopenia 35.96 15.04 22 35069 127651 50442382
Bradycardia 35.68 15.04 112 34979 64314 50505719
Blood pressure systolic increased 35.54 15.04 77 35014 35372 50534661
Myelocyte count increased 34.95 15.04 12 35079 341 50569692
Oedema peripheral 34.68 15.04 35 35056 157926 50412107
Granuloma 34.67 15.04 28 35063 4830 50565203
Injection site pain 34.36 15.04 17 35074 111007 50459026
Chills 33.21 15.04 144 34947 96543 50473490
Psoriatic arthropathy 33.01 15.04 89 35002 46943 50523090
Mean cell haemoglobin increased 32.83 15.04 20 35071 2200 50567833
Tri-iodothyronine free decreased 32.50 15.04 11 35080 299 50569734
Red blood cell count increased 32.14 15.04 21 35070 2610 50567423
Impaired healing 32.07 15.04 5 35086 69781 50500252
Thyroxine free increased 31.74 15.04 14 35077 787 50569246
Inflammation 31.57 15.04 99 34992 56813 50513220
Mean cell haemoglobin concentration decreased 30.55 15.04 21 35070 2838 50567195
Alopecia 30.54 15.04 79 35012 244968 50325065
Migraine 30.50 15.04 118 34973 75162 50494871
CFTR gene mutation 30.46 15.04 8 35083 87 50569946
Band sensation 30.41 15.04 13 35078 677 50569356
Tachycardia 30.10 15.04 143 34948 99620 50470413
Crystalluria 30.06 15.04 11 35080 378 50569655
Angina pectoris 29.89 15.04 60 35031 26128 50543905
Mean cell volume decreased 29.73 15.04 20 35071 2609 50567424
Neuropathy peripheral 29.66 15.04 15 35076 96742 50473291
Paranasal cyst 29.00 15.04 10 35081 288 50569745
Aspartate aminotransferase increased 28.98 15.04 119 34972 77879 50492154
Vascular malformation 28.84 15.04 10 35081 293 50569740
Band neutrophil percentage increased 27.81 15.04 9 35082 212 50569821
Disease progression 27.72 15.04 16 35075 95850 50474183
Monocyte count increased 27.57 15.04 26 35065 5513 50564520
Urinary retention 27.53 15.04 58 35033 26132 50543901
Anaemia 27.34 15.04 87 35004 252369 50317664
Throat irritation 27.30 15.04 63 35028 30176 50539857
Urine oxalate increased 27.19 15.04 9 35082 228 50569805
Drug ineffective for unapproved indication 27.02 15.04 51 35040 21230 50548803
Gingival bleeding 26.61 15.04 36 35055 11317 50558716
Rhinorrhoea 26.13 15.04 87 35004 51496 50518537
Bulimia nervosa 25.96 15.04 10 35081 397 50569636
Infection 25.39 15.04 51 35040 172903 50397130
Renal failure 25.31 15.04 22 35069 106611 50463422
Cough 25.26 15.04 267 34824 240997 50329036
Mastoiditis 24.92 15.04 12 35079 826 50569207
Pericarditis 24.42 15.04 12 35079 78677 50491356
Infusion site discomfort 24.38 15.04 12 35079 866 50569167
Injection site extravasation 24.34 15.04 28 35063 7473 50562560
Myelocyte percentage increased 24.05 15.04 8 35083 206 50569827
Drug abuse 23.91 15.04 6 35085 59840 50510193
Band neutrophil count increased 23.74 15.04 9 35082 342 50569691
Thyroid disorder 23.56 15.04 36 35055 12641 50557392
Renal pain 23.53 15.04 24 35067 5595 50564438
Infusion related reaction 23.39 15.04 199 34892 169358 50400675
Mean cell volume increased 23.08 15.04 18 35073 2954 50567079
Seizure 22.73 15.04 29 35062 117845 50452188
Teratoma benign 22.70 15.04 6 35085 67 50569966
Extrapyramidal disorder 22.69 15.04 34 35057 11736 50558297
Infusion site extravasation 22.57 15.04 26 35065 6950 50563083
Dizziness 22.52 15.04 351 34740 346018 50224015
Anuria 22.42 15.04 33 35058 11211 50558822
Abdominal pain 22.23 15.04 256 34835 235972 50334061
Drug tolerance 22.21 15.04 22 35069 4954 50565079
Myocardial reperfusion injury 22.11 15.04 5 35086 27 50570006
Depressive symptom 21.90 15.04 18 35073 3182 50566851
Retinal depigmentation 21.89 15.04 8 35083 274 50569759
Immune thrombocytopenia 21.75 15.04 29 35062 8988 50561045
Cardiac failure 21.55 15.04 13 35078 76027 50494006
Poor quality sleep 21.27 15.04 40 35051 16606 50553427
Irritable bowel syndrome 20.86 15.04 5 35086 51436 50518597
Infusion site scar 20.52 15.04 8 35083 328 50569705
Osteoarthritis 20.48 15.04 11 35080 68595 50501438
Creatinine urine increased 20.39 15.04 7 35084 199 50569834
Multiple organ dysfunction syndrome 20.20 15.04 5 35086 50332 50519701
Lip pruritus 20.17 15.04 10 35081 733 50569300
Palpitations 20.03 15.04 123 34968 94383 50475650
Brain death 19.78 15.04 16 35075 2767 50567266
Cerebrovascular accident 19.63 15.04 22 35069 94658 50475375
Rales 19.48 15.04 29 35062 9949 50560084
Urobilinogen urine increased 19.40 15.04 7 35084 231 50569802
Rheumatoid lung 19.29 15.04 15 35076 2450 50567583
Maternal exposure during pregnancy 18.76 15.04 53 35038 159725 50410308
Feeling abnormal 18.75 15.04 150 34941 125342 50444691
Gestational hypertension 18.72 15.04 14 35077 2159 50567874
Influenza 18.63 15.04 116 34975 89422 50480611
Fumbling 18.59 15.04 6 35085 140 50569893
Lymphoedema 18.52 15.04 27 35064 9095 50560938
Hypoglycaemia 18.48 15.04 7 35084 53574 50516459
Gastrointestinal disorder 18.45 15.04 23 35068 94433 50475600
Drug tolerance decreased 18.43 15.04 27 35064 9133 50560900
Thyroid stimulating immunoglobulin 18.29 15.04 5 35086 64 50569969
Interstitial lung disease 18.26 15.04 7 35084 53169 50516864
Limbal swelling 18.12 15.04 4 35087 19 50570014
Klebsiella test positive 18.05 15.04 10 35081 921 50569112
Arthritis 17.83 15.04 112 34979 86609 50483424
Vaginal discharge 17.75 15.04 20 35071 5220 50564813
Skin papilloma 17.60 15.04 18 35073 4211 50565822
Vitamin B12 decreased 17.54 15.04 15 35076 2800 50567233
Rhabdomyolysis 17.47 15.04 3 35088 39024 50531009
Ill-defined disorder 17.47 15.04 8 35083 54646 50515387
Colitis microscopic 17.34 15.04 22 35069 6498 50563535
Septic shock 17.32 15.04 9 35082 57166 50512867
Nasopharyngitis 17.22 15.04 207 34884 192720 50377313
Coma 17.16 15.04 9 35082 56870 50513163
Lipaemic index score 17.09 15.04 5 35086 83 50569950
Appetite disorder 16.85 15.04 21 35070 6093 50563940
Therapy non-responder 16.75 15.04 75 35016 50947 50519086
Dry throat 16.72 15.04 20 35071 5564 50564469
Thirst 16.71 15.04 28 35063 10622 50559411
Immature granulocyte count increased 16.66 15.04 7 35084 349 50569684
Angioedema 16.64 15.04 3 35088 37673 50532360
Injection site reaction 16.50 15.04 7 35084 50025 50520008
Respiration abnormal 16.48 15.04 19 35072 5083 50564950
Wrong technique in product usage process 16.43 15.04 9 35082 55501 50514532
Thyroid cyst 16.42 15.04 8 35083 565 50569468
Gastrointestinal haemorrhage 16.36 15.04 16 35075 73305 50496728
Allergic sinusitis 16.34 15.04 8 35083 571 50569462
Basophil count increased 16.30 15.04 9 35082 823 50569210
Blood cholesterol increased 16.27 15.04 9 35082 55206 50514827
Productive cough 16.22 15.04 76 35015 52618 50517415
Vertigo 16.13 15.04 75 35016 51757 50518276
Injection site bruising 16.08 15.04 3 35088 36765 50533268
Dyspepsia 16.05 15.04 97 34994 74000 50496033
Heart rate irregular 16.03 15.04 39 35052 19321 50550712
Blood luteinising hormone decreased 16.01 15.04 4 35087 35 50569998
Endometrial ablation 16.00 15.04 9 35082 854 50569179
Injection site erythema 15.99 15.04 17 35074 74919 50495114
Suicide attempt 15.88 15.04 8 35083 51724 50518309
Breast cancer 15.83 15.04 5 35086 42885 50527148
Large intestinal ulcer haemorrhage 15.77 15.04 5 35086 110 50569923
Pain 15.72 15.04 295 34796 578608 49991425
Infusion site swelling 15.68 15.04 22 35069 7154 50562879
Tinnitus 15.65 15.04 49 35042 28083 50541950
Hypokalaemia 15.60 15.04 23 35068 87969 50482064
Cardio-respiratory arrest 15.57 15.04 9 35082 53883 50516150
Decerebrate posture 15.44 15.04 5 35086 118 50569915
Haematocrit increased 15.42 15.04 12 35079 1962 50568071
Chronic gastrointestinal bleeding 15.36 15.04 5 35086 120 50569913
Menstrual disorder 15.35 15.04 17 35074 4353 50565680
Urinary casts 15.31 15.04 8 35083 655 50569378
Metabolic acidosis 15.30 15.04 4 35087 38821 50531212
Deep vein thrombosis 15.23 15.04 17 35074 73287 50496746

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Aplastic anaemia 200.82 17.57 79 9240 7431 29557777
Tenosynovitis 146.34 17.57 52 9267 3681 29561527
Enthesopathy 146.20 17.57 52 9267 3691 29561517
C-reactive protein abnormal 114.87 17.57 51 9268 6485 29558723
Tongue disorder 114.25 17.57 46 9273 4590 29560618
Victim of child abuse 112.05 17.57 30 9289 815 29564393
Synovitis 92.91 17.57 52 9267 10838 29554370
Alanine aminotransferase abnormal 92.91 17.57 35 9284 2922 29562286
Tendonitis 90.42 17.57 46 9273 7915 29557293
Respiratory depression 84.99 17.57 53 9266 13470 29551738
Erythema 77.93 17.57 107 9212 75499 29489709
Epidural lipomatosis 74.60 17.57 21 9298 690 29564518
Psoriatic arthropathy 71.35 17.57 49 9270 14642 29550566
Drug dependence 68.26 17.57 55 9264 20926 29544282
Febrile neutropenia 67.35 17.57 124 9195 112116 29453092
Loss of personal independence in daily activities 61.00 17.57 56 9263 25384 29539824
Foetal exposure during pregnancy 50.98 17.57 58 9261 33809 29531399
Product prescribing error 49.90 17.57 43 9276 17933 29547275
Platelet transfusion 49.33 17.57 17 9302 1097 29564111
Aspartate aminotransferase increased 46.30 17.57 74 9245 59651 29505557
Lymphocyte percentage decreased 46.21 17.57 19 9300 1998 29563210
Heart rate irregular 46.11 17.57 36 9283 13081 29552127
Urine abnormality 45.88 17.57 18 9301 1676 29563532
Juvenile idiopathic arthritis 45.60 17.57 17 9302 1377 29563831
Nausea 45.04 17.57 195 9124 289060 29276148
Blood pressure fluctuation 44.23 17.57 42 9277 19852 29545356
Alanine aminotransferase increased 43.26 17.57 79 9240 70865 29494343
Red blood cell sedimentation rate 43.22 17.57 13 9306 541 29564667
Mucosal inflammation 42.36 17.57 51 9268 31544 29533664
Granuloma skin 41.21 17.57 13 9306 635 29564573
Treatment failure 40.60 17.57 54 9265 36885 29528323
Death 39.75 17.57 30 9289 342054 29223154
Blood parathyroid hormone decreased 38.14 17.57 13 9306 811 29564397
Lymphocyte count decreased 37.81 17.57 38 9281 19233 29545975
Neutrophil percentage increased 34.86 17.57 15 9304 1766 29563442
Panniculitis 33.16 17.57 13 9306 1208 29564000
C-reactive protein increased 33.13 17.57 54 9265 44209 29520999
Congenital skin dimples 31.97 17.57 8 9311 165 29565043
Transfusion 30.00 17.57 22 9297 7276 29557932
Product use issue 28.48 17.57 55 9264 51389 29513819
Off label use 27.44 17.57 175 9144 300625 29264583
Epispadias 27.37 17.57 7 9312 158 29565050
pH urine increased 26.79 17.57 6 9313 75 29565133
Inappropriate schedule of product administration 26.42 17.57 49 9270 44423 29520785
Rheumatoid nodule 26.25 17.57 13 9306 2109 29563099
Drug hypersensitivity 26.22 17.57 63 9256 68343 29496865
Vomiting 24.85 17.57 132 9187 212128 29353080
Drug intolerance 24.70 17.57 50 9269 48329 29516879
Drug interaction 24.59 17.57 16 9303 197369 29367839
Headache 24.46 17.57 114 9205 173893 29391315
Contraindicated product administered 23.68 17.57 29 9290 18237 29546971
White blood cells urine positive 23.35 17.57 10 9309 1164 29564044
Specific gravity urine increased 23.23 17.57 6 9313 141 29565067
Urine leukocyte esterase positive 21.16 17.57 7 9312 398 29564810
Urine ketone body present 21.08 17.57 9 9310 1039 29564169
Red blood cell elliptocytes present 20.62 17.57 5 9314 90 29565118
Child abuse 20.55 17.57 6 9313 225 29564983
Pyloric stenosis 20.42 17.57 8 9311 742 29564466
Band neutrophil percentage increased 19.85 17.57 5 9314 106 29565102
Umbilical hernia 19.41 17.57 13 9306 3722 29561486
Congenital umbilical hernia 19.14 17.57 6 9313 287 29564921
Infusion related reaction 18.53 17.57 42 9277 43844 29521364
Obesity 18.52 17.57 19 9300 9844 29555364
Restrictive cardiomyopathy 18.46 17.57 7 9312 594 29564614
Aplasia 18.42 17.57 13 9306 4050 29561158
Heart rate decreased 18.10 17.57 30 9289 24882 29540326
Neutrophil percentage decreased 18.04 17.57 6 9313 347 29564861
Hypercalcaemia 17.75 17.57 21 9298 12738 29552470

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Urine abnormality 453.99 13.93 174 42350 7188 64449020
Lymphocyte count decreased 326.46 13.93 246 42278 40453 64415755
Enthesopathy 302.62 13.93 141 42383 9497 64446711
Urine leukocyte esterase positive 278.27 13.93 99 42425 3304 64452904
Tenosynovitis 275.13 13.93 141 42383 11692 64444516
Aplastic anaemia 264.59 13.93 145 42379 13775 64442433
Tongue disorder 260.93 13.93 137 42387 11943 64444265
White blood cells urine positive 223.97 13.93 96 42428 5302 64450906
Blood parathyroid hormone decreased 195.42 13.93 96 42428 7270 64448938
Red blood cell sedimentation rate 187.59 13.93 76 42448 3638 64452570
Blood urine present 183.91 13.93 127 42397 18213 64437995
Red blood cells urine positive 180.40 13.93 78 42446 4400 64451808
Panniculitis 178.48 13.93 96 42428 8783 64447425
Tendonitis 174.66 13.93 128 42396 20154 64436054
Alanine aminotransferase abnormal 174.51 13.93 87 42437 6801 64449407
Granuloma skin 166.64 13.93 81 42443 5993 64450215
Urine ketone body present 164.72 13.93 67 42457 3240 64452968
Urinary sediment present 160.24 13.93 59 42465 2175 64454033
C-reactive protein abnormal 157.83 13.93 140 42384 28907 64427301
Death 153.98 13.93 63 42461 482642 63973566
Rheumatoid nodule 151.89 13.93 98 42426 12553 64443655
Skin necrosis 138.45 13.93 97 42427 14232 64441976
Urine analysis abnormal 132.08 13.93 68 42456 5688 64450520
Flushing 131.69 13.93 207 42317 78441 64377767
Crystal urine present 131.22 13.93 49 42475 1880 64454328
Red cell distribution width increased 127.57 13.93 87 42437 12222 64443986
Loss of personal independence in daily activities 120.33 13.93 190 42334 72264 64383944
Nausea 120.25 13.93 906 41618 784894 63671314
Lymphocyte percentage decreased 115.64 13.93 58 42466 4591 64451617
Ulcer 111.55 13.93 104 42420 22886 64433322
Chest discomfort 111.12 13.93 240 42284 115866 64340342
Psoriatic arthropathy 106.61 13.93 137 42387 43144 64413064
Drug interaction 97.64 13.93 59 42465 362024 64094184
Haemoglobin urine present 97.53 13.93 32 42492 831 64455377
Headache 96.81 13.93 638 41886 528829 63927379
Erythema 96.70 13.93 307 42217 186763 64269445
Culture urine positive 95.13 13.93 49 42475 4102 64452106
Neutrophil percentage increased 94.80 13.93 50 42474 4395 64451813
Hypercalcaemia 92.81 13.93 109 42415 31307 64424901
Acute kidney injury 92.50 13.93 96 42428 449144 64007064
Fear of injection 91.87 13.93 54 42470 5858 64450350
Eosinophil count increased 90.88 13.93 75 42449 14037 64442171
Bacterial test positive 90.76 13.93 56 42468 6634 64449574
Bacterial test 90.73 13.93 33 42491 1174 64455034
Toxicity to various agents 90.21 13.93 65 42459 363448 64092760
Completed suicide 90.16 13.93 19 42505 224395 64231813
Neovascularisation 89.84 13.93 32 42492 1071 64455137
Victim of child abuse 89.26 13.93 30 42494 841 64455367
Specific gravity urine decreased 88.35 13.93 29 42495 754 64455454
Eosinophil percentage increased 81.87 13.93 32 42492 1392 64454816
Insomnia 79.81 13.93 299 42225 197537 64258671
Basal cell carcinoma 78.12 13.93 99 42425 30739 64425469
Blood pressure fluctuation 77.90 13.93 130 42394 51741 64404467
Feeling hot 77.52 13.93 121 42403 45542 64410666
Alanine aminotransferase increased 72.56 13.93 229 42295 138802 64317406
Monocyte percentage increased 71.38 13.93 32 42492 1968 64454240
Infusion site pain 70.62 13.93 57 42467 10340 64445868
Urticaria 69.99 13.93 235 42289 147082 64309126
Rash pruritic 69.61 13.93 131 42393 57273 64398935
Drug eruption 63.08 13.93 97 42427 36039 64420169
Poor venous access 61.83 13.93 57 42467 12360 64443848
Mean cell haemoglobin concentration increased 60.96 13.93 22 42502 765 64455443
Red cell distribution width decreased 60.86 13.93 24 42500 1069 64455139
Body temperature increased 60.63 13.93 96 42428 36570 64419638
Multiple sclerosis relapse 60.31 13.93 102 42422 41033 64415175
Anaemia 59.36 13.93 99 42425 378581 64077627
Monocyte count decreased 57.72 13.93 31 42493 2826 64453382
Gastric disorder 57.59 13.93 83 42441 29114 64427094
Oropharyngeal pain 56.46 13.93 157 42367 88710 64367498
Oesophageal spasm 55.55 13.93 29 42495 2496 64453712
Blood creatinine decreased 55.12 13.93 42 42482 7008 64449200
Epidural lipomatosis 55.02 13.93 21 42503 856 64455352
Migraine 54.77 13.93 125 42399 62552 64393656
Infusion related reaction 54.61 13.93 234 42290 164233 64291975
Hyperkalaemia 54.42 13.93 3 42521 101126 64355082
Blood uric acid decreased 53.69 13.93 22 42502 1084 64455124
C-reactive protein increased 52.90 13.93 160 42364 94749 64361459
Skin ulcer 52.87 13.93 100 42424 43874 64412334
pH urine increased 52.73 13.93 17 42507 417 64455791
Aspartate aminotransferase increased 52.44 13.93 186 42338 119602 64336606
Protein urine present 52.31 13.93 45 42479 8911 64447297
Specific gravity urine increased 52.27 13.93 17 42507 429 64455779
Hyponatraemia 51.13 13.93 17 42507 148322 64307886
Synovitis 49.65 13.93 161 42363 98929 64357279
Red blood cell sedimentation rate increased 49.20 13.93 80 42444 31155 64425053
Arterial occlusive disease 48.70 13.93 39 42485 6994 64449214
Cardiac failure congestive 48.58 13.93 13 42511 130567 64325641
Heart rate irregular 48.42 13.93 74 42450 27339 64428869
Alveolitis 47.79 13.93 30 42494 3662 64452546
Mean cell haemoglobin decreased 47.19 13.93 31 42493 4091 64452117
Confusional state 46.99 13.93 62 42462 261082 64195126
Renal failure 46.98 13.93 31 42493 181657 64274551
Heart rate decreased 46.10 13.93 108 42416 54959 64401249
Blood thyroid stimulating hormone increased 45.81 13.93 39 42485 7615 64448593
Body temperature decreased 45.81 13.93 70 42454 25858 64430350
Treatment failure 45.76 13.93 175 42349 116641 64339567
Heart rate increased 45.59 13.93 156 42368 98519 64357689
Gangrene 45.17 13.93 38 42486 7300 64448908
Oedema peripheral 44.26 13.93 44 42480 210273 64245935
Nitrite urine present 44.25 13.93 19 42505 1053 64455155
Blue toe syndrome 44.18 13.93 16 42508 562 64455646
Heart sounds 43.52 13.93 16 42508 587 64455621
Joint injury 43.46 13.93 64 42460 22883 64433325
Oesophageal pain 43.46 13.93 27 42497 3236 64452972
Product dose omission issue 43.02 13.93 39 42485 194708 64261500
Mean cell haemoglobin concentration decreased 42.89 13.93 28 42496 3656 64452552
Red blood cell count decreased 42.82 13.93 97 42427 48289 64407919
Blood thyroid stimulating hormone decreased 42.75 13.93 32 42492 5198 64451010
Band neutrophil percentage increased 41.80 13.93 14 42510 388 64455820
Cardiac failure 40.91 13.93 18 42506 132355 64323853
Creatinine urine decreased 40.82 13.93 12 42512 214 64455994
Paradoxical drug reaction 40.40 13.93 33 42491 6087 64450121
Disease progression 39.66 13.93 22 42502 141658 64314550
Haematocrit decreased 39.18 13.93 101 42423 54554 64401654
Inflammation 39.15 13.93 113 42411 65187 64391021
Febrile neutropenia 38.99 13.93 234 42290 187423 64268785
Prolonged expiration 38.69 13.93 16 42508 807 64455401
Red blood cells urine 38.61 13.93 15 42509 642 64455566
Band sensation 38.34 13.93 15 42509 654 64455554
Blood pressure systolic increased 38.18 13.93 94 42430 49359 64406849
Interstitial lung disease 37.76 13.93 9 42515 97723 64358485
Arteriovenous fistula occlusion 37.54 13.93 14 42510 535 64455673
Red blood cell count increased 36.53 13.93 25 42499 3530 64452678
Gastrointestinal haemorrhage 36.38 13.93 21 42503 132291 64323917
Blood pressure increased 36.38 13.93 216 42308 172336 64283872
Intestinal pseudo-obstruction 35.71 13.93 20 42504 1980 64454228
Stress 35.57 13.93 104 42420 60430 64395778
Urine leukocyte esterase 35.32 13.93 10 42514 155 64456053
Band neutrophil count increased 35.14 13.93 14 42510 641 64455567
Leukocyturia 34.79 13.93 18 42506 1520 64454688
Platelet transfusion 34.77 13.93 19 42505 1792 64454416
Cardio-respiratory arrest 34.39 13.93 11 42513 98382 64357826
Multiple organ dysfunction syndrome 34.28 13.93 12 42512 101401 64354807
Mean cell haemoglobin increased 34.05 13.93 23 42501 3179 64453029
Renal impairment 33.61 13.93 24 42500 134993 64321215
Infusion site extravasation 33.29 13.93 31 42493 6806 64449402
Inappropriate schedule of product administration 32.70 13.93 134 42390 92152 64364056
Rhabdomyolysis 32.51 13.93 10 42514 91716 64364492
Mean cell volume decreased 32.16 13.93 23 42501 3483 64452725
Throat irritation 31.68 13.93 68 42456 32643 64423565
Tri-iodothyronine free decreased 31.41 13.93 11 42513 350 64455858
Respiratory failure 31.36 13.93 36 42488 161147 64295061
Red blood cell elliptocytes present 31.35 13.93 9 42515 147 64456061
Transfusion 30.97 13.93 48 42476 17946 64438262
Product use issue 30.75 13.93 188 42336 151527 64304681
Respiratory depression 30.29 13.93 55 42469 23388 64432820
Granuloma 30.21 13.93 29 42495 6612 64449596
Neutrophil count increased 29.94 13.93 57 42467 25117 64431091
Vascular malformation 29.37 13.93 10 42514 292 64455916
Cardiac arrest 29.34 13.93 35 42489 154029 64302179
Monocyte count increased 28.93 13.93 31 42493 8048 64448160
Septic shock 28.61 13.93 17 42507 105420 64350788
Coma 28.55 13.93 11 42513 87604 64368604
Palpitations 28.23 13.93 140 42384 104348 64351860
Paranasal cyst 28.09 13.93 10 42514 334 64455874
Thyroxine free increased 28.09 13.93 14 42510 1093 64455115
Urine oxalate increased 27.90 13.93 9 42515 221 64455987
Drug tolerance decreased 27.11 13.93 28 42496 6970 64449238
CFTR gene mutation 27.02 13.93 7 42517 76 64456132
Myelocyte count increased 26.74 13.93 12 42512 740 64455468
Infusion site discomfort 26.52 13.93 12 42512 754 64455454
Drug dependence 26.43 13.93 64 42460 33248 64422960
Haematocrit increased 26.31 13.93 20 42504 3325 64452883
Therapy non-responder 26.02 13.93 99 42425 65800 64390408
Wound 25.93 13.93 9 42515 76468 64379740
Neuropathy peripheral 25.39 13.93 24 42500 117501 64338707
Fatigue 25.36 13.93 659 41865 748071 63708137
Nasopharyngitis 25.29 13.93 218 42306 195855 64260353
Rhinorrhoea 25.27 13.93 92 42432 59877 64396331
Chronic kidney disease 25.18 13.93 4 42520 57915 64398293
Lactic acidosis 25.05 13.93 5 42519 61405 64394803
Mental status changes 24.90 13.93 5 42519 61157 64395051
Thrombocytopenia 24.69 13.93 71 42453 223730 64232478
Tachycardia 24.63 13.93 176 42348 149403 64306805
Seizure 23.96 13.93 46 42478 166846 64289362
Lymphoedema 23.82 13.93 31 42493 9874 64446334
Injection site extravasation 23.78 13.93 28 42496 8058 64448150
Abdominal pain 23.68 13.93 312 42212 312063 64144145
Myelocyte percentage increased 23.19 13.93 8 42516 243 64455965
Arthritis 23.13 13.93 113 42411 83701 64372507
Rheumatoid arthritis 22.95 13.93 186 42338 164108 64292100
Chills 22.89 13.93 162 42362 137102 64319106
Infusion site scar 22.77 13.93 8 42516 257 64455951
Poor quality sleep 22.65 13.93 43 42481 18908 64437300
Gestational hypertension 22.62 13.93 14 42510 1667 64454541
Crystalluria 22.46 13.93 11 42513 827 64455381
Cerebrovascular accident 22.41 13.93 35 42489 137548 64318660
Myocardial reperfusion injury 22.36 13.93 5 42519 27 64456181
Hypoglycaemia 22.34 13.93 16 42508 89876 64366332
Pneumonia 22.21 13.93 249 42275 559327 63896881
Influenza 22.20 13.93 133 42391 106398 64349810
Cough 22.16 13.93 300 42224 301848 64154360
Rheumatoid lung 22.14 13.93 16 42508 2463 64453745
Deep vein thrombosis 22.12 13.93 22 42502 105160 64351048
Feeling abnormal 21.88 13.93 157 42367 133445 64322763
Feeling cold 21.54 13.93 48 42476 23630 64432578
Injection site pain 21.54 13.93 25 42499 111383 64344825
Angioedema 21.44 13.93 7 42517 61814 64394394
Dyspepsia 21.26 13.93 107 42417 80205 64376003
Retinal depigmentation 21.25 13.93 8 42516 314 64455894
Drug tolerance 21.18 13.93 23 42501 6062 64450146
Vaginal discharge 21.17 13.93 19 42505 3978 64452230
Mean cell volume increased 21.02 13.93 21 42503 5025 64451183
Orthostatic hypotension 20.84 13.93 3 42521 46735 64409473
Acute myocardial infarction 20.73 13.93 10 42514 69708 64386500
Coronary artery disease 20.68 13.93 7 42517 60426 64395782
Gingival bleeding 20.67 13.93 36 42488 14818 64441390
Diabetes mellitus 20.59 13.93 9 42515 66465 64389743
Respiration abnormal 20.48 13.93 23 42501 6292 64449916
Respiratory arrest 20.22 13.93 5 42519 52980 64403228
Therapeutic response shortened 20.18 13.93 29 42495 10141 64446067
Pneumonia aspiration 20.05 13.93 7 42517 59264 64396944
Menstrual disorder 19.84 13.93 17 42507 3348 64452860
Wrong technique in product usage process 19.81 13.93 9 42515 64965 64391243
Infusion site swelling 19.62 13.93 21 42503 5444 64450764
Mastoiditis 19.36 13.93 12 42512 1433 64454775
Bone marrow failure 19.35 13.93 4 42520 47948 64408260
Fumbling 19.18 13.93 6 42518 133 64456075
Cerebral haemorrhage 19.16 13.93 5 42519 51085 64405123
Creatinine urine increased 19.11 13.93 8 42516 416 64455792
Suicidal ideation 19.10 13.93 10 42514 66532 64389676
Urobilinogen urine increased 19.07 13.93 9 42515 623 64455585
Lipaemic index score 19.06 13.93 6 42518 136 64456072
Haematuria 19.03 13.93 8 42516 60463 64395745
Infusion site erythema 18.90 13.93 23 42501 6850 64449358
Renal pain 18.63 13.93 23 42501 6951 64449257
Pancreatitis acute 18.53 13.93 3 42521 42852 64413356
International normalised ratio increased 18.51 13.93 15 42509 79152 64377056
Thyroid disorder 18.48 13.93 30 42494 11662 64444546
Aggression 18.37 13.93 4 42520 46228 64409980
Thyroid stimulating immunoglobulin 18.27 13.93 5 42519 68 64456140
Limbal swelling 18.15 13.93 4 42520 20 64456188
Lip pruritus 18.14 13.93 9 42515 696 64455512
Syncope 18.12 13.93 49 42475 157586 64298622
Neutrophil percentage decreased 17.77 13.93 9 42515 727 64455481
Juvenile idiopathic arthritis 17.76 13.93 17 42507 3862 64452346
Sepsis 17.59 13.93 85 42439 230256 64225952
Klebsiella test positive 17.40 13.93 11 42513 1359 64454849
Mean platelet volume decreased 17.38 13.93 12 42512 1719 64454489
Pulmonary embolism 17.20 13.93 45 42479 146311 64309897
Suicide attempt 17.17 13.93 13 42511 70994 64385214
Metabolic acidosis 17.15 13.93 13 42511 70945 64385263
Hypokalaemia 17.15 13.93 34 42490 121869 64334339
Endometrial ablation 17.05 13.93 9 42515 792 64455416
Skin papilloma 16.96 13.93 19 42505 5184 64451024
Drug abuse 16.89 13.93 39 42485 132335 64323873
Drug ineffective for unapproved indication 16.87 13.93 52 42472 31081 64425127
Osteonecrosis of jaw 16.76 13.93 3 42521 39822 64416386
Peripheral swelling 16.71 13.93 211 42313 208942 64247266
Vitamin B12 decreased 16.59 13.93 14 42510 2701 64453507
Hepatic function abnormal 16.57 13.93 11 42513 64302 64391906
Child abuse 16.48 13.93 6 42518 214 64455994
Oedema 16.33 13.93 22 42502 91913 64364295
Rales 16.31 13.93 33 42491 15196 64441012
Hyperglycaemia 16.30 13.93 10 42514 60958 64395250
Acute respiratory distress syndrome 16.24 13.93 3 42521 38932 64417276
Dizziness 16.10 13.93 384 42140 429779 64026429
Osteoarthritis 16.10 13.93 11 42513 63325 64392883
Impaired healing 16.05 13.93 10 42514 60463 64395745
Drug intolerance 16.03 13.93 192 42332 187800 64268408
Dry throat 15.76 13.93 20 42504 6212 64449996
Depressive symptom 15.66 13.93 17 42507 4479 64451729
Sedation 15.66 13.93 4 42520 41458 64414750
Staphylococcal infection 15.48 13.93 7 42517 50671 64405537
Swelling 15.43 13.93 54 42470 160164 64296044
Basophil count increased 15.43 13.93 10 42514 1290 64454918
General physical health deterioration 15.39 13.93 204 42320 204221 64251987
Transient ischaemic attack 15.33 13.93 5 42519 44177 64412031
Appetite disorder 15.19 13.93 20 42504 6441 64449767
White blood cell count decreased 15.16 13.93 165 42359 157672 64298536
Infusion site pruritus 15.03 13.93 13 42511 2593 64453615
Allergic sinusitis 15.02 13.93 7 42517 471 64455737
Injection site reaction 14.97 13.93 6 42518 46658 64409550
Immature granulocyte count increased 14.91 13.93 7 42517 479 64455729
Injection site bruising 14.75 13.93 3 42521 36370 64419838
Haematoma 14.75 13.93 6 42518 46244 64409964
Anuria 14.58 13.93 36 42488 18928 64437280
Change in seizure presentation 14.54 13.93 6 42518 301 64455907
Serotonin syndrome 14.43 13.93 4 42520 39278 64416930
COVID-19 14.42 13.93 13 42511 65127 64391081
Pericarditis 14.42 13.93 12 42512 62504 64393704
Cystitis 14.35 13.93 61 42463 42614 64413594
Infusion site rash 14.35 13.93 9 42515 1097 64455111
Drug reaction with eosinophilia and systemic symptoms 14.34 13.93 9 42515 54208 64402000
Immune thrombocytopenia 14.22 13.93 31 42493 15035 64441173
Drug ineffective 14.22 13.93 434 42090 839813 63616395
Off label use 14.18 13.93 530 41994 632276 63823932
Rash 14.14 13.93 399 42125 458150 63998058
Tinnitus 14.07 13.93 52 42472 34081 64422127
Aplasia 14.05 13.93 20 42504 6933 64449275
Bradycardia 13.97 13.93 129 42395 118090 64338118
Infusion site bruising 13.94 13.93 10 42514 1522 64454686

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R06AA11 RESPIRATORY SYSTEM
ANTIHISTAMINES FOR SYSTEMIC USE
ANTIHISTAMINES FOR SYSTEMIC USE
Aminoalkyl ethers
CHEBI has role CHEBI:37955 H1 receptor antagonists
CHEBI has role CHEBI:50919 antiemetico
MeSH PA D000932 Antiemetics
MeSH PA D002491 Central Nervous System Agents
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D018494 Histamine Agents
MeSH PA D006633 Histamine Antagonists
MeSH PA D006634 Histamine H1 Antagonists
MeSH PA D018377 Neurotransmitter Agents
MeSH PA D018373 Peripheral Nervous System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Nausea and vomiting indication 16932000
Motion sickness indication 37031009 DOID:2951
Vertigo indication 399153001
Vomiting indication 422400008
Nausea indication 422587007
Prevention of Motion Sickness indication
Prevention of Nausea and Vomiting indication
Mรฉniรจre's disease off-label use 13445001 DOID:9849
Ocular hypertension contraindication 4210003 DOID:9282
Hypophosphatemia contraindication 4996001
Alcoholism contraindication 7200002
Peptic ulcer contraindication 13200003 DOID:750
Myocardial infarction contraindication 22298006 DOID:5844
Hyperthyroidism contraindication 34486009 DOID:7998
Hypertensive disorder contraindication 38341003 DOID:10763
Low blood pressure contraindication 45007003
Blood coagulation disorder contraindication 64779008 DOID:1247
Diabetes mellitus contraindication 73211009 DOID:9351
Hyperglycemia contraindication 80394007 DOID:4195
Chronic idiopathic constipation contraindication 82934008
Gout contraindication 90560007 DOID:13189
Liver function tests abnormal contraindication 166603001
Arterial hemorrhage contraindication 234003006
Disease of liver contraindication 235856003 DOID:409
Bladder outflow obstruction contraindication 236645006
Pyloric obstruction contraindication 244815007
Benign prostatic hyperplasia contraindication 266569009
Retention of urine contraindication 267064002
Thrombocytopenic disorder contraindication 302215000 DOID:1588
Angle-closure glaucoma contraindication 392291006 DOID:13550
Acute coronary syndrome contraindication 394659003
Disorder of coronary artery contraindication 414024009




๐Ÿถ Veterinary Drug Use

None

๐Ÿถ Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Histamine H1 receptor GPCR ANTAGONIST Ki 7.43 DRUG MATRIX CHEMBL
Sigma non-opioid intracellular receptor 1 Membrane receptor Ki 6.31 DRUG MATRIX
Sodium-dependent noradrenaline transporter Transporter Ki 5.70 DRUG MATRIX
5-hydroxytryptamine receptor 2A GPCR Ki 6.70 DRUG MATRIX
5-hydroxytryptamine receptor 2B GPCR Ki 5.96 DRUG MATRIX
5-hydroxytryptamine receptor 2C GPCR Ki 6.48 DRUG MATRIX
Alpha-2B adrenergic receptor GPCR Ki 5.60 DRUG MATRIX
Muscarinic acetylcholine receptor M1 GPCR Ki 6.96 DRUG MATRIX
Muscarinic acetylcholine receptor M2 GPCR Ki 6.79 DRUG MATRIX
Muscarinic acetylcholine receptor M3 GPCR Ki 7.02 DRUG MATRIX
Muscarinic acetylcholine receptor M4 GPCR Ki 7.10 DRUG MATRIX
Muscarinic acetylcholine receptor M5 GPCR Ki 6.64 DRUG MATRIX
Sodium-dependent dopamine transporter Transporter Ki 5.75 DRUG MATRIX
Cytochrome P450 2D6 Enzyme IC50 5.82 DRUG MATRIX
Alpha-2A adrenergic receptor GPCR Ki 5.79 DRUG MATRIX
Alpha-1D adrenergic receptor GPCR Ki 5.85 DRUG MATRIX

External reference:

IDSource
4018048 VUID
N0000146389 NUI
D00520 KEGG_DRUG
151666 RXNORM
4018048 VANDF
C0012381 UMLSCUI
CHEBI:4604 CHEBI
CHEMBL1200406 ChEMBL_ID
DB00985 DRUGBANK_ID
D004111 MESH_DESCRIPTOR_UI
10660 PUBCHEM_CID
61 INN_ID
JB937PER5C UNII
1568 MMSL
4605 MMSL
6646 MMSL
d00861 MMSL
003371 NDDF
387469006 SNOMEDCT_US
81073007 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Wal-Dram HUMAN OTC DRUG LABEL 1 0363-0198 TABLET 50 mg ORAL OTC MONOGRAPH FINAL 15 sections
Wal-Dram HUMAN OTC DRUG LABEL 1 0363-0198 TABLET 50 mg ORAL OTC MONOGRAPH FINAL 15 sections
Wal-Dram HUMAN OTC DRUG LABEL 1 0363-0198 TABLET 50 mg ORAL OTC MONOGRAPH FINAL 15 sections
Wal-Dram HUMAN OTC DRUG LABEL 1 0363-0198 TABLET 50 mg ORAL OTC MONOGRAPH FINAL 15 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 0363-1980 TABLET 50 mg ORAL OTC monograph final 15 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 0363-1980 TABLET 50 mg ORAL OTC monograph final 15 sections
Driminate HUMAN OTC DRUG LABEL 1 0904-2051 TABLET 50 mg ORAL OTC monograph final 15 sections
Driminate HUMAN OTC DRUG LABEL 1 0904-2051 TABLET 50 mg ORAL OTC monograph final 15 sections
Driminate HUMAN OTC DRUG LABEL 1 0904-2051 TABLET 50 mg ORAL OTC monograph final 15 sections
Driminate HUMAN OTC DRUG LABEL 1 0904-2051 TABLET 50 mg ORAL OTC monograph final 15 sections
Dimenhydrinate HUMAN OTC DRUG LABEL 1 0904-6772 TABLET 50 mg ORAL OTC monograph final 16 sections
PhysiciansCare DimenhydrinateMotion Sickness Relief HUMAN OTC DRUG LABEL 1 0924-1006 TABLET, COATED 50 mg ORAL OTC monograph final 16 sections
Dimenhydrinate HUMAN OTC DRUG LABEL 1 0924-1007 TABLET 50 mg ORAL OTC monograph final 17 sections
Gravol HUMAN OTC DRUG LABEL 1 10237-940 CAPSULE, LIQUID FILLED 50 mg ORAL OTC monograph final 15 sections
Gravol HUMAN OTC DRUG LABEL 1 10237-941 TABLET, COATED 50 mg ORAL OTC monograph final 15 sections
Gravol HUMAN OTC DRUG LABEL 1 10237-942 SYRUP 15 mg ORAL OTC monograph final 15 sections
Motion Sickness HUMAN OTC DRUG LABEL 1 11673-198 TABLET 50 mg ORAL OTC MONOGRAPH FINAL 15 sections
Motion Sickness HUMAN OTC DRUG LABEL 1 11673-198 TABLET 50 mg ORAL OTC MONOGRAPH FINAL 15 sections
Motion Sickness HUMAN OTC DRUG LABEL 1 11673-198 TABLET 50 mg ORAL OTC MONOGRAPH FINAL 15 sections
Motion Sickness HUMAN OTC DRUG LABEL 1 11673-198 TABLET 50 mg ORAL OTC MONOGRAPH FINAL 15 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 11822-0198 TABLET 50 mg ORAL OTC monograph final 15 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 11822-0198 TABLET 50 mg ORAL OTC monograph final 15 sections
Dramamine HUMAN OTC DRUG LABEL 1 29485-1216 TABLET, CHEWABLE 50 mg ORAL OTC monograph final 16 sections
Dramamine HUMAN OTC DRUG LABEL 1 29485-6925 TABLET, CHEWABLE 50 mg ORAL OTC monograph final 16 sections
Dramamine HUMAN OTC DRUG LABEL 1 29485-8048 TABLET, CHEWABLE 50 mg ORAL OTC monograph final 16 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 36800-930 TABLET 50 mg ORAL OTC monograph final 15 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 36800-930 TABLET 50 mg ORAL OTC monograph final 15 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 46122-536 TABLET 50 mg ORAL OTC monograph final 15 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 46122-536 TABLET 50 mg ORAL OTC monograph final 15 sections
Motion Sickness Relief HUMAN OTC DRUG LABEL 1 46122-536 TABLET 50 mg ORAL OTC monograph final 15 sections