DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
Search
Structure ๐
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
diloxanide furoate ๐ถ
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antiparasitics, salicylanilides and analogues
896
3736-81-0
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
diloxanide furoate
amebiazol
dichlofurazol
diclofurazol
diloxanid furoate
entamide furoate
furamide
furentomin
Molecular weight: 328.15
Formula: C14H11Cl2NO4
CLOGP: 3.09
LIPINSKI: 0
HAC: 5
HDO: 0
TPSA: 59.75
ALOGS: -3.93
ROTB: 5
Drug dosage:
None
ADMET properties:
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Property
Value
Reference
MRTD (Maximum Recommended Therapeutic Daily Dose)
65.30 ยตM/kg/day
Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BDDCS (Biopharmaceutical Drug Disposition Classification System)
2
Benet LZ, Broccatelli F, Oprea TI
EoM (Fraction excreted unchanged in urine)
1 %
Benet LZ, Broccatelli F, Oprea TI
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
CHEBI has role
CHEBI:50266
Prodrugs
CHEBI has role
CHEBI:171664
antiamoebic drugs
MeSH PA
D000563
Amebicides
MeSH PA
D000890
Anti-Infective Agents
MeSH PA
D000977
Antiparasitic Agents
MeSH PA
D000981
Antiprotozoal Agents
Showing 1 to 6 of 6 entries
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Amebic infection
indication
111910009
DOID:9181
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๐ถ Veterinary Drug Use
None
๐ถ Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
002955
NDDF
19529
PUBCHEM_CID
23203
RXNORM
396029009
SNOMEDCT_US
579-38-4
SECONDARY_CAS_RN
C004932
MESH_SUPPLEMENTAL_RECORD_UI
C0058181
UMLSCUI
CHEBI:4601
CHEBI
CHEMBL1334860
ChEMBL_ID
D02480
KEGG_DRUG
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Pharmaceutical products:
None
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diloxanide furoate