adamexine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
mucolytic, bromhexine derivatives 86 54785-02-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • broncostyl
  • adamexina
  • adamexine
mucolytic molecule in which cyclohexyl ring of bromhexine is replaced with adamantane
  • Molecular weight: 470.25
  • Formula: C20H26Br2N2O
  • CLOGP: 4.20
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 32.34
  • ALOGS: -6.22
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.02 acidic
pKa2 7.58 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C2700162 UMLSCUI
CHEBI:135761 CHEBI
CHEMBL2105546 ChEMBL_ID
C025184 MESH_SUPPLEMENTAL_RECORD_UI
4002 INN_ID
6LPU49W75V UNII
64387 PUBCHEM_CID

Pharmaceutical products:

None