Stem definition | Drug id | CAS RN |
---|---|---|
845 | 492-61-5 |
None
Property | Value | Reference |
---|---|---|
BA (Bioavailability) | 99 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
Jan. 17, 1946 | FDA | B BRAUN |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 388.84 | 9.83 | 775 | 111694 | 818558 | 49674097 |
Myelosuppression | 297.33 | 9.83 | 244 | 112225 | 13273 | 50479382 |
Hypokalaemia | 217.97 | 9.83 | 553 | 111916 | 87439 | 50405216 |
Rheumatoid arthritis | 203.30 | 9.83 | 98 | 112371 | 202452 | 50290203 |
Hand deformity | 202.83 | 9.83 | 4 | 112465 | 100195 | 50392460 |
Joint swelling | 199.70 | 9.83 | 152 | 112317 | 245134 | 50247521 |
Systemic lupus erythematosus | 199.07 | 9.83 | 36 | 112433 | 140586 | 50352069 |
Contraindicated product administered | 190.72 | 9.83 | 48 | 112421 | 148910 | 50343745 |
Cardiac failure congestive | 190.23 | 9.83 | 512 | 111957 | 83870 | 50408785 |
Glossodynia | 169.26 | 9.83 | 27 | 112442 | 115542 | 50377113 |
Alopecia | 162.62 | 9.83 | 183 | 112286 | 244864 | 50247791 |
Arthropathy | 162.10 | 9.83 | 74 | 112395 | 157832 | 50334823 |
Hyperkalaemia | 155.98 | 9.83 | 336 | 112133 | 47753 | 50444902 |
Hypervolaemia | 146.20 | 9.83 | 228 | 112241 | 25271 | 50467384 |
Pneumonia | 145.25 | 9.83 | 1379 | 111090 | 377022 | 50115633 |
Wound | 139.49 | 9.83 | 32 | 112437 | 105762 | 50386893 |
Therapeutic product effect decreased | 137.70 | 9.83 | 65 | 112404 | 135985 | 50356670 |
Colitis microscopic | 131.57 | 9.83 | 112 | 112357 | 6408 | 50486247 |
Blood potassium decreased | 130.11 | 9.83 | 267 | 112202 | 36678 | 50455977 |
Pericarditis | 123.16 | 9.83 | 15 | 112454 | 78674 | 50413981 |
Pneumonia aspiration | 118.67 | 9.83 | 232 | 112237 | 30772 | 50461883 |
Atrial fibrillation | 116.14 | 9.83 | 491 | 111978 | 101254 | 50391401 |
Bone marrow failure | 115.96 | 9.83 | 215 | 112254 | 27409 | 50465246 |
Pain | 114.38 | 9.83 | 786 | 111683 | 578117 | 49914538 |
Arthralgia | 112.66 | 9.83 | 547 | 111922 | 438155 | 50054500 |
Dehydration | 111.43 | 9.83 | 648 | 111821 | 151801 | 50340854 |
Drug intolerance | 111.15 | 9.83 | 198 | 112271 | 218906 | 50273749 |
Hypoxia | 110.95 | 9.83 | 306 | 112163 | 50817 | 50441838 |
Pulmonary hypertension | 107.78 | 9.83 | 233 | 112236 | 33184 | 50459471 |
Oedema peripheral | 106.86 | 9.83 | 658 | 111811 | 157303 | 50335352 |
Lower respiratory tract infection | 105.08 | 9.83 | 40 | 112429 | 95161 | 50397494 |
Respiratory failure | 100.94 | 9.83 | 436 | 112033 | 90745 | 50401910 |
Acute kidney injury | 99.98 | 9.83 | 856 | 111613 | 227202 | 50265453 |
Product use issue | 99.74 | 9.83 | 111 | 112358 | 149364 | 50343291 |
Off label use | 99.21 | 9.83 | 633 | 111836 | 473793 | 50018862 |
Infusion related reaction | 96.49 | 9.83 | 142 | 112327 | 169415 | 50323240 |
Abdominal discomfort | 95.87 | 9.83 | 235 | 112234 | 231406 | 50261249 |
Musculoskeletal stiffness | 92.97 | 9.83 | 89 | 112380 | 128392 | 50364263 |
Discomfort | 89.56 | 9.83 | 66 | 112403 | 108314 | 50384341 |
Acute respiratory failure | 86.40 | 9.83 | 195 | 112274 | 28587 | 50464068 |
Sepsis | 84.45 | 9.83 | 545 | 111924 | 132380 | 50360275 |
Swelling | 83.72 | 9.83 | 203 | 112266 | 200669 | 50291986 |
Right ventricular failure | 82.72 | 9.83 | 136 | 112333 | 15757 | 50476898 |
Helicobacter infection | 81.51 | 9.83 | 8 | 112461 | 49694 | 50442961 |
Drug hypersensitivity | 81.11 | 9.83 | 286 | 112183 | 250724 | 50241931 |
Glaucoma | 76 | 9.83 | 130 | 112339 | 15556 | 50477099 |
Drug abuse | 73.30 | 9.83 | 21 | 112448 | 59825 | 50432830 |
Gastrointestinal haemorrhage | 73.16 | 9.83 | 340 | 112129 | 72981 | 50419674 |
Plasma cell myeloma | 71.46 | 9.83 | 191 | 112278 | 31131 | 50461524 |
Pleural effusion | 71.43 | 9.83 | 364 | 112105 | 81090 | 50411565 |
Rash | 71.19 | 9.83 | 626 | 111843 | 436845 | 50055810 |
Hypotension | 69.29 | 9.83 | 814 | 111655 | 234655 | 50258000 |
Pulmonary arterial hypertension | 68.19 | 9.83 | 144 | 112325 | 20175 | 50472480 |
Cytokine release syndrome | 66.76 | 9.83 | 89 | 112380 | 8545 | 50484110 |
Therapeutic product effect incomplete | 66.64 | 9.83 | 63 | 112406 | 91452 | 50401203 |
Anaemia | 66.63 | 9.83 | 855 | 111614 | 251601 | 50241054 |
Muscle injury | 66.40 | 9.83 | 4 | 112465 | 37107 | 50455548 |
Gastrooesophageal reflux disease | 63.87 | 9.83 | 337 | 112132 | 76091 | 50416564 |
Folliculitis | 62.55 | 9.83 | 7 | 112462 | 39218 | 50453437 |
Maternal exposure during pregnancy | 60.03 | 9.83 | 170 | 112299 | 159608 | 50333047 |
Treatment failure | 59.78 | 9.83 | 136 | 112333 | 137501 | 50355154 |
Fluid retention | 59.75 | 9.83 | 247 | 112222 | 50402 | 50442253 |
Pulmonary oedema | 58.79 | 9.83 | 240 | 112229 | 48698 | 50443957 |
Hypersensitivity | 58.76 | 9.83 | 262 | 112207 | 214899 | 50277756 |
Diverticulitis | 55.31 | 9.83 | 181 | 112288 | 33001 | 50459654 |
Renal failure | 55.20 | 9.83 | 416 | 112053 | 106217 | 50386438 |
Blood urea increased | 54.99 | 9.83 | 145 | 112324 | 23440 | 50469215 |
Febrile neutropenia | 54.55 | 9.83 | 388 | 112081 | 97279 | 50395376 |
Synovitis | 52.50 | 9.83 | 124 | 112345 | 123741 | 50368914 |
Dyspnoea | 52.15 | 9.83 | 1588 | 110881 | 546020 | 49946635 |
Hepatic enzyme increased | 51.72 | 9.83 | 146 | 112323 | 137234 | 50355421 |
Asthenia | 51.53 | 9.83 | 995 | 111474 | 318047 | 50174608 |
Non-cardiogenic pulmonary oedema | 50.38 | 9.83 | 25 | 112444 | 556 | 50492099 |
Irritable bowel syndrome | 49.86 | 9.83 | 26 | 112443 | 51415 | 50441240 |
Chronic obstructive pulmonary disease | 49.09 | 9.83 | 242 | 112227 | 53193 | 50439462 |
Nasopharyngitis | 49.08 | 9.83 | 241 | 112228 | 192686 | 50299969 |
Coma | 49.03 | 9.83 | 253 | 112216 | 56626 | 50436029 |
International normalised ratio increased | 48.99 | 9.83 | 208 | 112261 | 42944 | 50449711 |
Mental status changes | 48.51 | 9.83 | 184 | 112285 | 36088 | 50456567 |
Diarrhoea | 48.14 | 9.83 | 1676 | 110793 | 586800 | 49905855 |
Haemoglobin decreased | 47.75 | 9.83 | 462 | 112007 | 126754 | 50365901 |
White blood cell count decreased | 46.85 | 9.83 | 430 | 112039 | 116292 | 50376363 |
Blood bilirubin increased | 46.60 | 9.83 | 167 | 112302 | 31871 | 50460784 |
Impaired healing | 46.32 | 9.83 | 52 | 112417 | 69734 | 50422921 |
Deep vein thrombosis | 45.55 | 9.83 | 299 | 112170 | 73005 | 50419650 |
Cardiac arrest | 45.36 | 9.83 | 330 | 112139 | 83321 | 50409334 |
Renal ischaemia | 44.49 | 9.83 | 23 | 112446 | 559 | 50492096 |
Injection site pain | 44.03 | 9.83 | 115 | 112354 | 110909 | 50381746 |
Psoriatic arthropathy | 43.79 | 9.83 | 25 | 112444 | 47007 | 50445648 |
Abortion spontaneous | 43.72 | 9.83 | 19 | 112450 | 41753 | 50450902 |
Bronchitis | 43.47 | 9.83 | 387 | 112082 | 103772 | 50388883 |
Hypoglycaemia | 43.21 | 9.83 | 234 | 112235 | 53347 | 50439308 |
Ill-defined disorder | 41.72 | 9.83 | 36 | 112433 | 54618 | 50438037 |
Electrolyte imbalance | 41.51 | 9.83 | 107 | 112362 | 17062 | 50475593 |
Diabetes insipidus | 40.48 | 9.83 | 37 | 112432 | 2327 | 50490328 |
PO2 increased | 39.64 | 9.83 | 24 | 112445 | 798 | 50491857 |
Hyponatraemia | 39.50 | 9.83 | 356 | 112113 | 95783 | 50396872 |
Injection site reaction | 38.14 | 9.83 | 33 | 112436 | 49999 | 50442656 |
Oedema | 38.13 | 9.83 | 277 | 112192 | 69904 | 50422751 |
Injection site bruising | 38.04 | 9.83 | 17 | 112452 | 36751 | 50455904 |
Heparin-induced thrombocytopenia | 37.19 | 9.83 | 45 | 112424 | 3920 | 50488735 |
Toxicity to various agents | 36.27 | 9.83 | 300 | 112169 | 212199 | 50280456 |
Thrombocytopenia | 36.00 | 9.83 | 438 | 112031 | 127235 | 50365420 |
Suicidal ideation | 35.96 | 9.83 | 42 | 112427 | 55343 | 50437312 |
Injection site erythema | 35.91 | 9.83 | 70 | 112399 | 74866 | 50417789 |
Atrial flutter | 35.27 | 9.83 | 67 | 112402 | 8696 | 50483959 |
Blood magnesium decreased | 35.04 | 9.83 | 77 | 112392 | 11083 | 50481572 |
Encephalopathy | 34.84 | 9.83 | 158 | 112311 | 33553 | 50459102 |
C-reactive protein abnormal | 33.60 | 9.83 | 10 | 112459 | 27799 | 50464856 |
Peritonitis bacterial | 32.94 | 9.83 | 46 | 112423 | 4615 | 50488040 |
Decreased appetite | 32.50 | 9.83 | 627 | 111842 | 200296 | 50292359 |
Intentional self-injury | 32.49 | 9.83 | 6 | 112463 | 23106 | 50469549 |
Brain natriuretic peptide increased | 32.48 | 9.83 | 45 | 112424 | 4482 | 50488173 |
PCO2 increased | 32.44 | 9.83 | 24 | 112445 | 1119 | 50491536 |
Pregnancy | 31.68 | 9.83 | 13 | 112456 | 29564 | 50463091 |
Injection site swelling | 31.30 | 9.83 | 28 | 112441 | 41745 | 50450910 |
Cor pulmonale | 31.27 | 9.83 | 29 | 112440 | 1858 | 50490797 |
Dementia | 31.04 | 9.83 | 92 | 112377 | 15905 | 50476750 |
Hypernatraemia | 30.11 | 9.83 | 52 | 112417 | 6269 | 50486386 |
Completed suicide | 30.03 | 9.83 | 171 | 112298 | 131718 | 50360937 |
Arthritis | 29.87 | 9.83 | 96 | 112373 | 86625 | 50406030 |
Blood alkaline phosphatase increased | 29.65 | 9.83 | 163 | 112306 | 37363 | 50455292 |
Septic shock | 29.53 | 9.83 | 223 | 112246 | 56952 | 50435703 |
Calcium deficiency | 29.35 | 9.83 | 21 | 112448 | 929 | 50491726 |
Cardiomegaly | 29.33 | 9.83 | 90 | 112379 | 15855 | 50476800 |
Full blood count decreased | 28.76 | 9.83 | 112 | 112357 | 22234 | 50470421 |
Pancytopenia | 28.53 | 9.83 | 299 | 112170 | 83731 | 50408924 |
Death | 28.32 | 9.83 | 934 | 111535 | 324445 | 50168210 |
Intentional product use issue | 28.01 | 9.83 | 83 | 112386 | 76835 | 50415820 |
Cardiac dysfunction | 27.92 | 9.83 | 26 | 112443 | 1675 | 50490980 |
Psoriasis | 27.71 | 9.83 | 71 | 112398 | 68929 | 50423726 |
Loss of personal independence in daily activities | 27.43 | 9.83 | 73 | 112396 | 69977 | 50422678 |
Hypomagnesaemia | 27.36 | 9.83 | 113 | 112356 | 23043 | 50469612 |
Acute left ventricular failure | 27.34 | 9.83 | 19 | 112450 | 802 | 50491853 |
Wrong technique in product usage process | 27.34 | 9.83 | 51 | 112418 | 55459 | 50437196 |
Hip arthroplasty | 27.17 | 9.83 | 17 | 112452 | 30412 | 50462243 |
Hypovolaemia | 27.15 | 9.83 | 63 | 112406 | 9402 | 50483253 |
Platelet count decreased | 26.86 | 9.83 | 342 | 112127 | 100384 | 50392271 |
Infection | 26.49 | 9.83 | 251 | 112218 | 172703 | 50319952 |
Product use in unapproved indication | 26.45 | 9.83 | 150 | 112319 | 115669 | 50376986 |
Sinusitis | 26.35 | 9.83 | 247 | 112222 | 170311 | 50322344 |
Transfusion | 25.78 | 9.83 | 75 | 112394 | 12830 | 50479825 |
Haematocrit decreased | 25.70 | 9.83 | 149 | 112320 | 34827 | 50457828 |
Prothrombin time prolonged | 25.54 | 9.83 | 59 | 112410 | 8779 | 50483876 |
Headache | 25.24 | 9.83 | 897 | 111572 | 505638 | 49987017 |
Vomiting | 24.94 | 9.83 | 1257 | 111212 | 459501 | 50033154 |
Granulocytopenia | 24.87 | 9.83 | 43 | 112426 | 5188 | 50487467 |
Bacteraemia | 24.29 | 9.83 | 79 | 112390 | 14354 | 50478301 |
Blood bicarbonate decreased | 24.06 | 9.83 | 30 | 112439 | 2695 | 50489960 |
Neutrophil count decreased | 24.04 | 9.83 | 180 | 112289 | 45846 | 50446809 |
Metabolic alkalosis | 24.01 | 9.83 | 30 | 112439 | 2701 | 50489954 |
Condition aggravated | 23.95 | 9.83 | 491 | 111978 | 296567 | 50196088 |
Aspartate aminotransferase increased | 23.48 | 9.83 | 271 | 112198 | 77727 | 50414928 |
Knee arthroplasty | 23.47 | 9.83 | 27 | 112442 | 35819 | 50456836 |
Activated partial thromboplastin time prolonged | 23.39 | 9.83 | 47 | 112422 | 6355 | 50486300 |
Ascites | 23.32 | 9.83 | 148 | 112321 | 35713 | 50456942 |
Cardiogenic shock | 23.27 | 9.83 | 82 | 112387 | 15517 | 50477138 |
Urinary tract infection | 23.20 | 9.83 | 657 | 111812 | 223363 | 50269292 |
Atelectasis | 23.05 | 9.83 | 91 | 112378 | 18179 | 50474476 |
Injection site pruritus | 22.80 | 9.83 | 34 | 112435 | 40377 | 50452278 |
Tonsillar haemorrhage | 22.52 | 9.83 | 11 | 112458 | 236 | 50492419 |
Failure to thrive | 22.43 | 9.83 | 46 | 112423 | 6312 | 50486343 |
Oxygen consumption increased | 22.21 | 9.83 | 33 | 112436 | 3503 | 50489152 |
Urine chloride decreased | 22.07 | 9.83 | 8 | 112461 | 78 | 50492577 |
Red blood cell sedimentation rate increased | 21.70 | 9.83 | 20 | 112449 | 29396 | 50463259 |
Electrocardiogram T wave peaked | 21.30 | 9.83 | 10 | 112459 | 196 | 50492459 |
Respiratory distress | 21.19 | 9.83 | 128 | 112341 | 30361 | 50462294 |
Therapeutic response decreased | 21.03 | 9.83 | 46 | 112423 | 47185 | 50445470 |
Blood albumin decreased | 20.98 | 9.83 | 71 | 112398 | 13165 | 50479490 |
Blood pressure decreased | 20.93 | 9.83 | 203 | 112266 | 55706 | 50436949 |
Gastrointestinal disorder | 20.68 | 9.83 | 124 | 112345 | 94332 | 50398323 |
Toxic epidermal necrolysis | 20.66 | 9.83 | 97 | 112372 | 20895 | 50471760 |
Supraventricular tachycardia | 20.59 | 9.83 | 69 | 112400 | 12732 | 50479923 |
Blood cholesterol increased | 20.53 | 9.83 | 59 | 112410 | 55156 | 50437499 |
Product compounding quality issue | 20.32 | 9.83 | 6 | 112463 | 28 | 50492627 |
Small intestinal obstruction | 20.25 | 9.83 | 80 | 112389 | 15988 | 50476667 |
Mobility decreased | 20.23 | 9.83 | 100 | 112369 | 79848 | 50412807 |
Blood potassium increased | 20.15 | 9.83 | 81 | 112388 | 16317 | 50476338 |
Blood pH decreased | 20.05 | 9.83 | 26 | 112443 | 2429 | 50490226 |
Sleep disorder | 20.01 | 9.83 | 63 | 112406 | 57220 | 50435435 |
Pulse absent | 19.65 | 9.83 | 37 | 112432 | 4769 | 50487886 |
Hypophagia | 19.65 | 9.83 | 117 | 112352 | 27611 | 50465044 |
Oxygen saturation abnormal | 19.59 | 9.83 | 27 | 112442 | 2675 | 50489980 |
Fatigue | 19.52 | 9.83 | 1333 | 111136 | 706268 | 49786387 |
Cardiac failure acute | 19.51 | 9.83 | 51 | 112418 | 8199 | 50484456 |
Generalised oedema | 19.48 | 9.83 | 71 | 112398 | 13660 | 50478995 |
Urticaria | 19.42 | 9.83 | 189 | 112280 | 129372 | 50363283 |
Cardiac failure | 19.35 | 9.83 | 256 | 112213 | 75784 | 50416871 |
Blister | 19.30 | 9.83 | 111 | 112358 | 85307 | 50407348 |
Mental status changes postoperative | 19.28 | 9.83 | 9 | 112460 | 174 | 50492481 |
Dyspnoea exertional | 19.17 | 9.83 | 186 | 112283 | 51047 | 50441608 |
Bezoar | 19.09 | 9.83 | 19 | 112450 | 1329 | 50491326 |
Inflammation | 18.90 | 9.83 | 64 | 112405 | 56848 | 50435807 |
Tachypnoea | 18.71 | 9.83 | 73 | 112396 | 14504 | 50478151 |
Arrhythmia | 18.70 | 9.83 | 132 | 112337 | 33000 | 50459655 |
Disability | 18.65 | 9.83 | 3 | 112466 | 12772 | 50479883 |
Malnutrition | 18.54 | 9.83 | 68 | 112401 | 13121 | 50479534 |
Blood pressure fluctuation | 18.46 | 9.83 | 32 | 112437 | 35791 | 50456864 |
Torsade de pointes | 18.34 | 9.83 | 63 | 112406 | 11772 | 50480883 |
Pulmonary embolism | 18.02 | 9.83 | 322 | 112147 | 101382 | 50391273 |
Immune effector cell-associated neurotoxicity syndrome | 17.77 | 9.83 | 17 | 112452 | 1133 | 50491522 |
Foetal death | 17.77 | 9.83 | 49 | 112420 | 8131 | 50484524 |
Ventricular tachycardia | 17.75 | 9.83 | 76 | 112393 | 15745 | 50476910 |
Hyperglycaemia | 17.69 | 9.83 | 140 | 112329 | 36265 | 50456390 |
Atrioventricular block first degree | 17.49 | 9.83 | 41 | 112428 | 6160 | 50486495 |
Product residue present | 17.22 | 9.83 | 30 | 112439 | 3642 | 50489013 |
Urine sodium decreased | 17.22 | 9.83 | 8 | 112461 | 153 | 50492502 |
Constipation | 17.14 | 9.83 | 537 | 111932 | 185171 | 50307484 |
Coagulopathy | 17.00 | 9.83 | 82 | 112387 | 17862 | 50474793 |
Inappropriate schedule of product administration | 16.96 | 9.83 | 92 | 112377 | 71739 | 50420916 |
Drug reaction with eosinophilia and systemic symptoms | 16.94 | 9.83 | 23 | 112446 | 28401 | 50464254 |
Metabolic encephalopathy | 16.84 | 9.83 | 36 | 112433 | 5085 | 50487570 |
Foot deformity | 16.78 | 9.83 | 11 | 112458 | 19199 | 50473456 |
Thyroid disorder | 16.69 | 9.83 | 64 | 112405 | 12613 | 50480042 |
Joint stiffness | 16.62 | 9.83 | 26 | 112443 | 30282 | 50462373 |
Blood chloride decreased | 16.46 | 9.83 | 35 | 112434 | 4926 | 50487729 |
Catheter management | 16.41 | 9.83 | 25 | 112444 | 2714 | 50489941 |
Blood creatinine increased | 16.41 | 9.83 | 249 | 112220 | 75911 | 50416744 |
Thrombosis | 16.36 | 9.83 | 193 | 112276 | 55640 | 50437015 |
Blood glucose increased | 16.07 | 9.83 | 235 | 112234 | 71089 | 50421566 |
Clostridium difficile colitis | 16.04 | 9.83 | 80 | 112389 | 17662 | 50474993 |
Blood potassium abnormal | 15.89 | 9.83 | 22 | 112447 | 2190 | 50490465 |
Leukocytosis | 15.82 | 9.83 | 95 | 112374 | 22484 | 50470171 |
Syncope | 15.81 | 9.83 | 319 | 112150 | 102683 | 50389972 |
Serotonin syndrome | 15.76 | 9.83 | 19 | 112450 | 24694 | 50467961 |
Disease progression | 15.76 | 9.83 | 300 | 112169 | 95566 | 50397089 |
Neuropathy peripheral | 15.63 | 9.83 | 302 | 112167 | 96455 | 50396200 |
Colitis | 15.47 | 9.83 | 142 | 112327 | 38387 | 50454268 |
Hepatocellular injury | 15.46 | 9.83 | 21 | 112448 | 25926 | 50466729 |
Confusion postoperative | 15.45 | 9.83 | 8 | 112461 | 195 | 50492460 |
Acinetobacter sepsis | 15.33 | 9.83 | 3 | 112466 | 0 | 50492655 |
Grip strength decreased | 15.31 | 9.83 | 4 | 112465 | 12117 | 50480538 |
Skin dystrophy | 15.24 | 9.83 | 5 | 112464 | 35 | 50492620 |
Chest pain | 15.16 | 9.83 | 507 | 111962 | 176375 | 50316280 |
Exposure during pregnancy | 15.14 | 9.83 | 184 | 112285 | 120831 | 50371824 |
Unresponsive to stimuli | 15.03 | 9.83 | 118 | 112351 | 30491 | 50462164 |
Lethargy | 14.98 | 9.83 | 172 | 112297 | 49260 | 50443395 |
Acute respiratory distress syndrome | 14.93 | 9.83 | 89 | 112380 | 21010 | 50471645 |
Muscle spasticity | 14.79 | 9.83 | 10 | 112459 | 17174 | 50475481 |
Pseudomonal bacteraemia | 14.70 | 9.83 | 16 | 112453 | 1243 | 50491412 |
Chronic kidney disease | 14.68 | 9.83 | 144 | 112325 | 39627 | 50453028 |
Oxalosis | 14.55 | 9.83 | 5 | 112464 | 41 | 50492614 |
Multiple sclerosis relapse | 14.48 | 9.83 | 48 | 112421 | 42916 | 50449739 |
Normal newborn | 14.45 | 9.83 | 40 | 112429 | 6651 | 50486004 |
Accidental exposure to product | 14.42 | 9.83 | 18 | 112451 | 23039 | 50469616 |
Tenosynovitis | 14.31 | 9.83 | 3 | 112466 | 10562 | 50482093 |
Burkholderia test positive | 14.20 | 9.83 | 8 | 112461 | 232 | 50492423 |
Drug eruption | 14.17 | 9.83 | 19 | 112450 | 23587 | 50469068 |
Hypoalbuminaemia | 14.00 | 9.83 | 51 | 112418 | 9809 | 50482846 |
Asthma | 13.94 | 9.83 | 129 | 112340 | 89208 | 50403447 |
Cellulitis | 13.93 | 9.83 | 228 | 112241 | 70570 | 50422085 |
Congestive hepatopathy | 13.87 | 9.83 | 22 | 112447 | 2472 | 50490183 |
Incision site pain | 13.86 | 9.83 | 14 | 112455 | 997 | 50491658 |
Oesophageal spasm | 13.81 | 9.83 | 21 | 112448 | 2275 | 50490380 |
Posterior reversible encephalopathy syndrome | 13.80 | 9.83 | 8 | 112461 | 14920 | 50477735 |
Infantile apnoea | 13.67 | 9.83 | 13 | 112456 | 860 | 50491795 |
Bradycardia | 13.63 | 9.83 | 210 | 112259 | 64216 | 50428439 |
Multiple drug therapy | 13.52 | 9.83 | 19 | 112450 | 1918 | 50490737 |
Cerebrovascular accident | 13.47 | 9.83 | 290 | 112179 | 94390 | 50398265 |
Injection site warmth | 13.44 | 9.83 | 7 | 112462 | 13859 | 50478796 |
Posthaemorrhagic hydrocephalus | 13.32 | 9.83 | 4 | 112465 | 20 | 50492635 |
Cholelithiasis | 13.30 | 9.83 | 136 | 112333 | 37837 | 50454818 |
Device related sepsis | 13.29 | 9.83 | 26 | 112443 | 3449 | 50489206 |
Catheter site extravasation | 13.16 | 9.83 | 8 | 112461 | 268 | 50492387 |
Electrocardiogram abnormal | 13.14 | 9.83 | 42 | 112427 | 7563 | 50485092 |
General physical health deterioration | 13.12 | 9.83 | 230 | 112239 | 142204 | 50350451 |
Metabolic acidosis | 13.10 | 9.83 | 138 | 112331 | 38687 | 50453968 |
Multiple allergies | 13.07 | 9.83 | 45 | 112424 | 8418 | 50484237 |
Sinoatrial block | 13.02 | 9.83 | 12 | 112457 | 763 | 50491892 |
Blood cholesterol decreased | 13.00 | 9.83 | 12 | 112457 | 764 | 50491891 |
Alkalosis | 12.92 | 9.83 | 8 | 112461 | 277 | 50492378 |
Pericardial effusion | 12.76 | 9.83 | 99 | 112370 | 25490 | 50467165 |
Tendonitis | 12.75 | 9.83 | 11 | 112458 | 16694 | 50475961 |
Pneumothorax spontaneous | 12.69 | 9.83 | 11 | 112458 | 645 | 50492010 |
Chronic respiratory failure | 12.65 | 9.83 | 17 | 112452 | 1645 | 50491010 |
Nodal arrhythmia | 12.63 | 9.83 | 14 | 112455 | 1110 | 50491545 |
Transient ischaemic attack | 12.57 | 9.83 | 118 | 112351 | 32092 | 50460563 |
Acne | 12.57 | 9.83 | 15 | 112454 | 19580 | 50473075 |
Nail dystrophy | 12.55 | 9.83 | 12 | 112457 | 799 | 50491856 |
Skin reaction | 12.54 | 9.83 | 55 | 112414 | 11513 | 50481142 |
Cytotoxic oedema | 12.40 | 9.83 | 6 | 112463 | 126 | 50492529 |
Vascular device infection | 12.38 | 9.83 | 29 | 112440 | 4355 | 50488300 |
Red blood cell count decreased | 12.24 | 9.83 | 122 | 112347 | 33713 | 50458942 |
Neonatal infection | 12.11 | 9.83 | 6 | 112463 | 133 | 50492522 |
Hyperchloraemia | 12.06 | 9.83 | 11 | 112458 | 690 | 50491965 |
Abortion incomplete complicated | 12.05 | 9.83 | 3 | 112466 | 6 | 50492649 |
Cyst | 12.04 | 9.83 | 6 | 112463 | 12181 | 50480474 |
Herpes zoster | 12.02 | 9.83 | 100 | 112369 | 70686 | 50421969 |
Haemorrhage | 12.00 | 9.83 | 176 | 112293 | 53265 | 50439390 |
Retinal ischaemia | 11.96 | 9.83 | 8 | 112461 | 317 | 50492338 |
Catheter site haemorrhage | 11.95 | 9.83 | 22 | 112447 | 2788 | 50489867 |
Mitral valve incompetence | 11.92 | 9.83 | 73 | 112396 | 17398 | 50475257 |
Osteonecrosis of jaw | 11.91 | 9.83 | 35 | 112434 | 32491 | 50460164 |
Central nervous system injury | 11.91 | 9.83 | 6 | 112463 | 138 | 50492517 |
Product selection error | 11.86 | 9.83 | 5 | 112464 | 75 | 50492580 |
Blood glucose decreased | 11.74 | 9.83 | 75 | 112394 | 18136 | 50474519 |
Macular degeneration | 11.70 | 9.83 | 63 | 112406 | 14325 | 50478330 |
Ataxia | 11.65 | 9.83 | 61 | 112408 | 13725 | 50478930 |
Hyperdynamic left ventricle | 11.64 | 9.83 | 6 | 112463 | 145 | 50492510 |
Hyperaldosteronism | 11.61 | 9.83 | 7 | 112462 | 231 | 50492424 |
Vascular access malfunction | 11.41 | 9.83 | 4 | 112465 | 35 | 50492620 |
Hepatitis | 11.40 | 9.83 | 34 | 112435 | 31419 | 50461236 |
Serratia sepsis | 11.40 | 9.83 | 5 | 112464 | 83 | 50492572 |
Atrioventricular block second degree | 11.39 | 9.83 | 25 | 112444 | 3596 | 50489059 |
Paracentesis | 11.32 | 9.83 | 12 | 112457 | 904 | 50491751 |
Disseminated intravascular coagulation | 11.32 | 9.83 | 71 | 112398 | 17064 | 50475591 |
Orthopnoea | 11.30 | 9.83 | 33 | 112436 | 5656 | 50486999 |
Unevaluable event | 11.26 | 9.83 | 154 | 112315 | 45912 | 50446743 |
Infusion site necrosis | 11.22 | 9.83 | 4 | 112465 | 37 | 50492618 |
Device difficult to use | 11.16 | 9.83 | 4 | 112465 | 9882 | 50482773 |
Electrocardiogram U wave present | 11.14 | 9.83 | 5 | 112464 | 88 | 50492567 |
Lung infiltration | 11.14 | 9.83 | 59 | 112410 | 13334 | 50479321 |
Paraesthesia | 11.13 | 9.83 | 194 | 112275 | 120049 | 50372606 |
Polyuria | 11.11 | 9.83 | 38 | 112431 | 7083 | 50485572 |
Product substitution issue | 11.04 | 9.83 | 9 | 112460 | 14048 | 50478607 |
Therapy cessation | 11.04 | 9.83 | 26 | 112443 | 25985 | 50466670 |
Somnolence | 11.01 | 9.83 | 435 | 112034 | 154550 | 50338105 |
Haemodynamic instability | 10.97 | 9.83 | 41 | 112428 | 7983 | 50484672 |
Nodule | 10.92 | 9.83 | 13 | 112456 | 16990 | 50475665 |
Stomatitis | 10.88 | 9.83 | 159 | 112310 | 101185 | 50391470 |
Injection site rash | 10.79 | 9.83 | 12 | 112457 | 16165 | 50476490 |
Blood aldosterone abnormal | 10.77 | 9.83 | 4 | 112465 | 42 | 50492613 |
Oesophageal pain | 10.76 | 9.83 | 21 | 112448 | 2781 | 50489874 |
Coeliac disease | 10.72 | 9.83 | 3 | 112466 | 8682 | 50483973 |
Ischaemic hepatitis | 10.71 | 9.83 | 17 | 112452 | 1912 | 50490743 |
Tachycardia | 10.70 | 9.83 | 294 | 112175 | 99469 | 50393186 |
Product storage error | 10.68 | 9.83 | 7 | 112462 | 12217 | 50480438 |
Oxygen saturation decreased | 10.63 | 9.83 | 225 | 112244 | 73023 | 50419632 |
Gout | 10.57 | 9.83 | 52 | 112417 | 11418 | 50481237 |
Ventricular fibrillation | 10.55 | 9.83 | 49 | 112420 | 10510 | 50482145 |
Sedation | 10.45 | 9.83 | 34 | 112435 | 30576 | 50462079 |
Emphysema | 10.45 | 9.83 | 44 | 112425 | 9049 | 50483606 |
Fall | 10.44 | 9.83 | 872 | 111597 | 334060 | 50158595 |
Pulmonary arterial pressure increased | 10.40 | 9.83 | 23 | 112446 | 3325 | 50489330 |
Impaired work ability | 10.39 | 9.83 | 9 | 112460 | 13631 | 50479024 |
Blindness cortical | 10.36 | 9.83 | 8 | 112461 | 398 | 50492257 |
Hypercapnia | 10.33 | 9.83 | 28 | 112441 | 4599 | 50488056 |
Osteoarthritis | 10.30 | 9.83 | 100 | 112369 | 68506 | 50424149 |
Peptic ulcer | 10.29 | 9.83 | 25 | 112444 | 3841 | 50488814 |
Vascular pseudoaneurysm | 10.29 | 9.83 | 14 | 112455 | 1370 | 50491285 |
Potassium wasting nephropathy | 10.29 | 9.83 | 4 | 112465 | 48 | 50492607 |
Oral herpes | 10.24 | 9.83 | 19 | 112450 | 20706 | 50471949 |
Blood pressure diastolic abnormal | 10.21 | 9.83 | 4 | 112465 | 9357 | 50483298 |
Splenic injury | 10.14 | 9.83 | 6 | 112463 | 191 | 50492464 |
Weight increased | 10.12 | 9.83 | 357 | 112112 | 201534 | 50291121 |
Oxygen therapy | 10.10 | 9.83 | 16 | 112453 | 1796 | 50490859 |
Haemodialysis | 10.03 | 9.83 | 41 | 112428 | 8321 | 50484334 |
Peripheral circulatory failure | 10.02 | 9.83 | 9 | 112460 | 553 | 50492102 |
Supraventricular extrasystoles | 9.97 | 9.83 | 25 | 112444 | 3919 | 50488736 |
Fibromyalgia | 9.86 | 9.83 | 59 | 112410 | 44919 | 50447736 |
Vertigo | 9.84 | 9.83 | 71 | 112398 | 51761 | 50440894 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 139.79 | 10.25 | 429 | 70533 | 362741 | 29140824 |
Hypokalaemia | 130.49 | 10.25 | 337 | 70625 | 49866 | 29453699 |
Drug abuse | 124.44 | 10.25 | 21 | 70941 | 79862 | 29423703 |
Appendicolith | 106.91 | 10.25 | 79 | 70883 | 3401 | 29500164 |
Cardiac failure congestive | 103.17 | 10.25 | 410 | 70552 | 76171 | 29427394 |
Cardiogenic shock | 91.74 | 10.25 | 165 | 70797 | 19025 | 29484540 |
Hypotension | 70.90 | 10.25 | 745 | 70217 | 193609 | 29309956 |
Myelosuppression | 67.42 | 10.25 | 112 | 70850 | 12115 | 29491450 |
Abdominal distension | 63.55 | 10.25 | 248 | 70714 | 45663 | 29457902 |
Hyperkalaemia | 60.85 | 10.25 | 300 | 70662 | 61092 | 29442473 |
Heparin-induced thrombocytopenia | 58.77 | 10.25 | 66 | 70896 | 4913 | 29498652 |
Appendicitis | 57.49 | 10.25 | 87 | 70875 | 8692 | 29494873 |
Sepsis | 56.78 | 10.25 | 557 | 70405 | 142125 | 29361440 |
Blood potassium decreased | 56.57 | 10.25 | 120 | 70842 | 15614 | 29487951 |
Hypervolaemia | 56.49 | 10.25 | 128 | 70834 | 17417 | 29486148 |
Off label use | 54.58 | 10.25 | 461 | 70501 | 300339 | 29203226 |
Ascites | 54.12 | 10.25 | 202 | 70760 | 36417 | 29467148 |
Atrial fibrillation | 48.32 | 10.25 | 425 | 70537 | 105221 | 29398344 |
Incision site pain | 47.11 | 10.25 | 37 | 70925 | 1746 | 29501819 |
Treatment failure | 47.02 | 10.25 | 15 | 70947 | 36924 | 29466641 |
Suicide attempt | 43.16 | 10.25 | 14 | 70948 | 34096 | 29469469 |
Tachypnoea | 42.92 | 10.25 | 105 | 70857 | 15010 | 29488555 |
Cytokine release syndrome | 42.55 | 10.25 | 96 | 70866 | 13023 | 29490542 |
Stress | 40.90 | 10.25 | 129 | 70833 | 21361 | 29482204 |
International normalised ratio increased | 40.56 | 10.25 | 212 | 70750 | 44160 | 29459405 |
Rheumatoid arthritis | 39.28 | 10.25 | 14 | 70948 | 32138 | 29471427 |
Therapeutic product effect incomplete | 38.89 | 10.25 | 23 | 70939 | 39282 | 29464283 |
Multiple organ dysfunction syndrome | 38.24 | 10.25 | 271 | 70691 | 62845 | 29440720 |
Oedema peripheral | 38.13 | 10.25 | 398 | 70564 | 103159 | 29400406 |
Administration site extravasation | 37.40 | 10.25 | 20 | 70942 | 482 | 29503083 |
Blood urea increased | 37.38 | 10.25 | 150 | 70812 | 27962 | 29475603 |
Toxicity to various agents | 35.19 | 10.25 | 258 | 70704 | 173403 | 29330162 |
Spinal muscular atrophy | 35.02 | 10.25 | 16 | 70946 | 271 | 29503294 |
Injection site pain | 35.01 | 10.25 | 17 | 70945 | 32429 | 29471136 |
Right ventricular failure | 34.13 | 10.25 | 65 | 70897 | 7825 | 29495740 |
Lung consolidation | 33.05 | 10.25 | 50 | 70912 | 4993 | 29498572 |
Pneumonia | 32.01 | 10.25 | 999 | 69963 | 319173 | 29184392 |
Diaphragmatic spasm | 31.43 | 10.25 | 11 | 70951 | 88 | 29503477 |
Burkholderia test positive | 31.41 | 10.25 | 23 | 70939 | 976 | 29502589 |
Faecal volume decreased | 29.82 | 10.25 | 11 | 70951 | 104 | 29503461 |
Cardiac failure | 29.30 | 10.25 | 305 | 70657 | 78982 | 29424583 |
Bone marrow failure | 28.51 | 10.25 | 136 | 70826 | 27313 | 29476252 |
Arthralgia | 27.98 | 10.25 | 208 | 70754 | 139409 | 29364156 |
Soft tissue mass | 27.95 | 10.25 | 18 | 70944 | 618 | 29502947 |
Mental status changes | 27.32 | 10.25 | 160 | 70802 | 34767 | 29468798 |
Overdose | 27.25 | 10.25 | 99 | 70863 | 79720 | 29423845 |
Haemoglobin decreased | 27.02 | 10.25 | 387 | 70575 | 107988 | 29395577 |
Dehydration | 25.98 | 10.25 | 403 | 70559 | 114345 | 29389220 |
Respiratory failure | 25.89 | 10.25 | 351 | 70611 | 96780 | 29406785 |
Toxic epidermal necrolysis | 25.86 | 10.25 | 99 | 70863 | 18054 | 29485511 |
Constipation | 25.48 | 10.25 | 400 | 70562 | 113760 | 29389805 |
Drug interaction | 25.26 | 10.25 | 328 | 70634 | 197057 | 29306508 |
Multimorbidity | 25.11 | 10.25 | 16 | 70946 | 539 | 29503026 |
Lymphocyte count decreased | 24.17 | 10.25 | 101 | 70861 | 19170 | 29484395 |
Gastrointestinal haemorrhage | 23.97 | 10.25 | 294 | 70668 | 79239 | 29424326 |
Pulmonary hypertension | 23.71 | 10.25 | 98 | 70864 | 18510 | 29485055 |
Dyspnoea | 23.65 | 10.25 | 983 | 69979 | 325749 | 29177816 |
Acute respiratory failure | 23.33 | 10.25 | 125 | 70837 | 26277 | 29477288 |
Fluid retention | 23.22 | 10.25 | 115 | 70847 | 23445 | 29480120 |
Red blood cells urine positive | 22.93 | 10.25 | 24 | 70938 | 1649 | 29501916 |
Pulmonary arterial hypertension | 22.49 | 10.25 | 53 | 70909 | 7396 | 29496169 |
Serotonin syndrome | 22.48 | 10.25 | 7 | 70955 | 17505 | 29486060 |
Headache | 22.31 | 10.25 | 289 | 70673 | 173718 | 29329847 |
Asthenia | 21.80 | 10.25 | 673 | 70289 | 214577 | 29288988 |
Drug reaction with eosinophilia and systemic symptoms | 21.77 | 10.25 | 21 | 70941 | 27971 | 29475594 |
Intentional product misuse | 21.59 | 10.25 | 31 | 70931 | 34630 | 29468935 |
Ventricular fibrillation | 21.46 | 10.25 | 85 | 70877 | 15748 | 29487817 |
Ventricular tachycardia | 21.41 | 10.25 | 109 | 70853 | 22465 | 29481100 |
Respiratory tract infection bacterial | 21.31 | 10.25 | 15 | 70947 | 598 | 29502967 |
Atelectasis | 21.16 | 10.25 | 83 | 70879 | 15309 | 29488256 |
Metabolic alkalosis | 21.14 | 10.25 | 20 | 70942 | 1216 | 29502349 |
Superinfection | 21.05 | 10.25 | 25 | 70937 | 1976 | 29501589 |
Drug resistance | 20.75 | 10.25 | 13 | 70949 | 21527 | 29482038 |
Oesophageal perforation | 20.67 | 10.25 | 16 | 70946 | 739 | 29502826 |
Plasma cell myeloma | 20.54 | 10.25 | 156 | 70806 | 36959 | 29466606 |
Sputum increased | 20.15 | 10.25 | 24 | 70938 | 1903 | 29501662 |
Oedema | 20.13 | 10.25 | 166 | 70796 | 40317 | 29463248 |
Rales | 20.09 | 10.25 | 51 | 70911 | 7459 | 29496106 |
Hyponatraemia | 19.94 | 10.25 | 249 | 70713 | 67384 | 29436181 |
Psoriasis | 19.90 | 10.25 | 29 | 70933 | 32198 | 29471367 |
Hypoxia | 19.79 | 10.25 | 187 | 70775 | 47192 | 29456373 |
Product use in unapproved indication | 19.58 | 10.25 | 125 | 70837 | 86750 | 29416815 |
Chills | 19.13 | 10.25 | 258 | 70704 | 71042 | 29432523 |
Pneumococcal sepsis | 18.74 | 10.25 | 16 | 70946 | 850 | 29502715 |
Hypernatraemia | 18.56 | 10.25 | 49 | 70913 | 7337 | 29496228 |
Drug intolerance | 17.86 | 10.25 | 58 | 70904 | 48321 | 29455244 |
Intentional self-injury | 17.86 | 10.25 | 4 | 70958 | 12457 | 29491108 |
Sedation | 17.48 | 10.25 | 10 | 70952 | 17395 | 29486170 |
Blood creatinine increased | 17.42 | 10.25 | 294 | 70668 | 84808 | 29418757 |
Blood bilirubin increased | 17.40 | 10.25 | 140 | 70822 | 33753 | 29469812 |
Acute kidney injury | 17.35 | 10.25 | 790 | 70172 | 264477 | 29239088 |
Pulse absent | 17.24 | 10.25 | 38 | 70924 | 5075 | 29498490 |
Increased bronchial secretion | 17.04 | 10.25 | 20 | 70942 | 1561 | 29502004 |
Cardiac arrest | 16.90 | 10.25 | 294 | 70668 | 85297 | 29418268 |
Vocal cord paralysis | 16.55 | 10.25 | 15 | 70947 | 863 | 29502702 |
Pulmonary oedema | 16.54 | 10.25 | 166 | 70796 | 42569 | 29460996 |
Renal tubular acidosis | 16.51 | 10.25 | 21 | 70941 | 1782 | 29501783 |
Intentional product use issue | 16.36 | 10.25 | 50 | 70912 | 42448 | 29461117 |
Interstitial lung disease | 16.32 | 10.25 | 77 | 70885 | 57641 | 29445924 |
Suicidal ideation | 16.29 | 10.25 | 37 | 70925 | 34679 | 29468886 |
Therapeutic product effect prolonged | 16.28 | 10.25 | 9 | 70953 | 232 | 29503333 |
Cytomegalovirus infection | 16.28 | 10.25 | 19 | 70943 | 23196 | 29480369 |
Disease complication | 16.12 | 10.25 | 24 | 70938 | 2362 | 29501203 |
Hypoglycaemia | 16.01 | 10.25 | 182 | 70780 | 48164 | 29455401 |
Musculoskeletal stiffness | 15.94 | 10.25 | 42 | 70920 | 37416 | 29466149 |
Cardiomyopathy | 15.89 | 10.25 | 74 | 70888 | 14713 | 29488852 |
Blood pressure fluctuation | 15.38 | 10.25 | 15 | 70947 | 19879 | 29483686 |
Motor neurone disease | 15.28 | 10.25 | 10 | 70952 | 353 | 29503212 |
Sensory integrative dysfunction | 15.24 | 10.25 | 5 | 70957 | 32 | 29503533 |
Device related infection | 15.18 | 10.25 | 76 | 70886 | 15560 | 29488005 |
Shoshin beriberi | 15.14 | 10.25 | 6 | 70956 | 70 | 29503495 |
Aggression | 15.01 | 10.25 | 40 | 70922 | 35501 | 29468064 |
Therapeutic product effect decreased | 14.97 | 10.25 | 30 | 70932 | 29421 | 29474144 |
White blood cell count decreased | 14.93 | 10.25 | 282 | 70680 | 83080 | 29420485 |
Cardiac dysfunction | 14.91 | 10.25 | 20 | 70942 | 1787 | 29501778 |
Bacteraemia | 14.91 | 10.25 | 78 | 70884 | 16245 | 29487320 |
Emotional disorder of childhood | 14.86 | 10.25 | 5 | 70957 | 35 | 29503530 |
Joint swelling | 14.75 | 10.25 | 65 | 70897 | 49565 | 29454000 |
Sopor | 14.72 | 10.25 | 4 | 70958 | 10930 | 29492635 |
Loss of personal independence in daily activities | 14.65 | 10.25 | 24 | 70938 | 25416 | 29478149 |
Epididymitis | 14.57 | 10.25 | 22 | 70940 | 2193 | 29501372 |
Oesophagitis | 14.57 | 10.25 | 62 | 70900 | 11861 | 29491704 |
Product use issue | 14.33 | 10.25 | 69 | 70893 | 51375 | 29452190 |
Resuscitation | 14.19 | 10.25 | 16 | 70946 | 1196 | 29502369 |
Endotracheal intubation | 14.11 | 10.25 | 24 | 70938 | 2645 | 29500920 |
Blood glucose increased | 14.04 | 10.25 | 209 | 70753 | 58775 | 29444790 |
Protein urine present | 13.74 | 10.25 | 33 | 70929 | 4661 | 29498904 |
Infusion site necrosis | 13.74 | 10.25 | 4 | 70958 | 16 | 29503549 |
Blood albumin decreased | 13.67 | 10.25 | 60 | 70902 | 11635 | 29491930 |
Posthaemorrhagic hydrocephalus | 13.50 | 10.25 | 6 | 70956 | 95 | 29503470 |
Pleural effusion | 13.48 | 10.25 | 245 | 70717 | 71663 | 29431902 |
Cardiomegaly | 13.40 | 10.25 | 67 | 70895 | 13709 | 29489856 |
Mobility decreased | 13.33 | 10.25 | 26 | 70936 | 25754 | 29477811 |
Biliary obstruction | 13.15 | 10.25 | 22 | 70940 | 2392 | 29501173 |
Obstructive airways disorder | 13.11 | 10.25 | 5 | 70957 | 11011 | 29492554 |
Gastric ischaemia | 13.03 | 10.25 | 3 | 70959 | 3 | 29503562 |
Product substitution issue | 13.03 | 10.25 | 3 | 70959 | 9169 | 29494396 |
Visual acuity reduced | 12.98 | 10.25 | 10 | 70952 | 14866 | 29488699 |
Swelling of eyelid | 12.91 | 10.25 | 11 | 70951 | 583 | 29502982 |
Compartment syndrome | 12.90 | 10.25 | 22 | 70940 | 2430 | 29501135 |
Drug dependence | 12.84 | 10.25 | 19 | 70943 | 20962 | 29482603 |
Blood potassium increased | 12.69 | 10.25 | 69 | 70893 | 14582 | 29488983 |
Angioedema | 12.68 | 10.25 | 37 | 70925 | 31878 | 29471687 |
Myalgia | 12.65 | 10.25 | 115 | 70847 | 73904 | 29429661 |
Ileus | 12.59 | 10.25 | 68 | 70894 | 14334 | 29489231 |
Stoma closure | 12.42 | 10.25 | 6 | 70956 | 116 | 29503449 |
Hypomagnesaemia | 12.37 | 10.25 | 78 | 70884 | 17390 | 29486175 |
Cortical visual impairment | 12.28 | 10.25 | 4 | 70958 | 25 | 29503540 |
Ventricular extrasystoles | 12.15 | 10.25 | 54 | 70908 | 10528 | 29493037 |
Hyperinsulinaemia | 12.07 | 10.25 | 5 | 70957 | 66 | 29503499 |
Product dose omission issue | 11.99 | 10.25 | 161 | 70801 | 96222 | 29407343 |
Lung infiltration | 11.97 | 10.25 | 58 | 70904 | 11721 | 29491844 |
Febrile neutropenia | 11.88 | 10.25 | 353 | 70609 | 111887 | 29391678 |
Insomnia | 11.88 | 10.25 | 146 | 70816 | 88615 | 29414950 |
Therapeutic response decreased | 11.87 | 10.25 | 26 | 70936 | 24685 | 29478880 |
Platelet count decreased | 11.85 | 10.25 | 332 | 70630 | 104340 | 29399225 |
Drug chemical incompatibility | 11.82 | 10.25 | 3 | 70959 | 6 | 29503559 |
Lactobacillus test positive | 11.77 | 10.25 | 4 | 70958 | 29 | 29503536 |
Intentional overdose | 11.73 | 10.25 | 50 | 70912 | 38478 | 29465087 |
Product preparation error | 11.64 | 10.25 | 17 | 70945 | 1645 | 29501920 |
Oropharyngeal pain | 11.59 | 10.25 | 34 | 70928 | 29251 | 29474314 |
Skin warm | 11.57 | 10.25 | 18 | 70944 | 1842 | 29501723 |
Pericardial fibrosis | 11.54 | 10.25 | 4 | 70958 | 31 | 29503534 |
Clostridium difficile colitis | 11.30 | 10.25 | 62 | 70900 | 13150 | 29490415 |
Mental impairment | 11.13 | 10.25 | 4 | 70958 | 9137 | 29494428 |
Tumour lysis syndrome | 11.11 | 10.25 | 64 | 70898 | 13820 | 29489745 |
Failure to thrive | 11.02 | 10.25 | 42 | 70920 | 7642 | 29495923 |
Pantoea agglomerans infection | 11.02 | 10.25 | 4 | 70958 | 36 | 29503529 |
Tachycardia | 10.99 | 10.25 | 239 | 70723 | 72171 | 29431394 |
Carbon dioxide decreased | 10.98 | 10.25 | 15 | 70947 | 1364 | 29502201 |
Metamyelocyte percentage increased | 10.97 | 10.25 | 3 | 70959 | 9 | 29503556 |
Urine potassium increased | 10.97 | 10.25 | 3 | 70959 | 9 | 29503556 |
Haematocrit decreased | 10.87 | 10.25 | 112 | 70850 | 28910 | 29474655 |
Abdominal pain | 10.84 | 10.25 | 412 | 70550 | 134945 | 29368620 |
Bilirubin conjugated increased | 10.83 | 10.25 | 23 | 70939 | 2994 | 29500571 |
Disturbance in attention | 10.74 | 10.25 | 22 | 70940 | 21402 | 29482163 |
Blood chloride decreased | 10.67 | 10.25 | 25 | 70937 | 3476 | 29500089 |
Urticaria | 10.66 | 10.25 | 82 | 70880 | 54578 | 29448987 |
Somnolence | 10.61 | 10.25 | 160 | 70802 | 93795 | 29409770 |
Inappropriate schedule of product administration | 10.52 | 10.25 | 63 | 70899 | 44409 | 29459156 |
Transplant failure | 10.52 | 10.25 | 22 | 70940 | 2834 | 29500731 |
Alveolar lung disease | 10.50 | 10.25 | 8 | 70954 | 361 | 29503204 |
Cardiac sarcoidosis | 10.47 | 10.25 | 4 | 70958 | 42 | 29503523 |
Hospitalisation | 10.44 | 10.25 | 66 | 70896 | 45922 | 29457643 |
Chest X-ray abnormal | 10.39 | 10.25 | 26 | 70936 | 3768 | 29499797 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Myelosuppression | 353.34 | 9.58 | 351 | 149275 | 23479 | 64325627 |
Drug ineffective | 347.39 | 9.58 | 913 | 148713 | 839334 | 63509772 |
Hypokalaemia | 293.97 | 9.58 | 779 | 148847 | 121124 | 64227982 |
Cardiac failure congestive | 212.98 | 9.58 | 727 | 148899 | 129853 | 64219253 |
Hyperkalaemia | 188.22 | 9.58 | 589 | 149037 | 100540 | 64248566 |
Drug abuse | 187.85 | 9.58 | 39 | 149587 | 132335 | 64216771 |
Hypervolaemia | 183.02 | 9.58 | 323 | 149303 | 37962 | 64311144 |
Rheumatoid arthritis | 181.29 | 9.58 | 77 | 149549 | 164217 | 64184889 |
Joint swelling | 173.22 | 9.58 | 147 | 149479 | 215235 | 64133871 |
Blood potassium decreased | 140.58 | 9.58 | 298 | 149328 | 40101 | 64309005 |
Bone marrow failure | 140.24 | 9.58 | 330 | 149296 | 47622 | 64301484 |
Pneumonia | 137.33 | 9.58 | 1936 | 147690 | 557640 | 63791466 |
Sepsis | 135.64 | 9.58 | 957 | 148669 | 229384 | 64119722 |
Off label use | 132.73 | 9.58 | 892 | 148734 | 631914 | 63717192 |
Hand deformity | 131.04 | 9.58 | 3 | 149623 | 62768 | 64286338 |
Arthropathy | 129.78 | 9.58 | 59 | 149567 | 120908 | 64228198 |
Atrial fibrillation | 127.18 | 9.58 | 754 | 148872 | 170335 | 64178771 |
Arthralgia | 127.04 | 9.58 | 561 | 149065 | 441699 | 63907407 |
Hypotension | 121.83 | 9.58 | 1385 | 148241 | 379589 | 63969517 |
Therapeutic product effect decreased | 110.75 | 9.58 | 65 | 149561 | 115286 | 64233820 |
Appendicolith | 109.51 | 9.58 | 79 | 149547 | 3390 | 64345716 |
Hypoxia | 108.04 | 9.58 | 448 | 149178 | 87701 | 64261405 |
Colitis microscopic | 107.43 | 9.58 | 108 | 149518 | 7324 | 64341782 |
Cardiogenic shock | 105.73 | 9.58 | 233 | 149393 | 32194 | 64316912 |
Pulmonary hypertension | 105.19 | 9.58 | 277 | 149349 | 42862 | 64306244 |
Oedema peripheral | 104.14 | 9.58 | 839 | 148787 | 209478 | 64139628 |
Cytokine release syndrome | 103.79 | 9.58 | 179 | 149447 | 20650 | 64328456 |
Systemic lupus erythematosus | 98.17 | 9.58 | 29 | 149597 | 77583 | 64271523 |
Right ventricular failure | 97.29 | 9.58 | 177 | 149449 | 21294 | 64327812 |
Respiratory failure | 96.16 | 9.58 | 672 | 148954 | 160511 | 64188595 |
Contraindicated product administered | 93.68 | 9.58 | 68 | 149558 | 107761 | 64241345 |
Acute respiratory failure | 92.07 | 9.58 | 290 | 149336 | 49644 | 64299462 |
Dehydration | 91.17 | 9.58 | 834 | 148792 | 215929 | 64133177 |
Heparin-induced thrombocytopenia | 90.56 | 9.58 | 105 | 149521 | 8374 | 64340732 |
Wound | 85.67 | 9.58 | 35 | 149591 | 76442 | 64272664 |
Pericarditis | 85.46 | 9.58 | 20 | 149606 | 62496 | 64286610 |
Musculoskeletal stiffness | 84.11 | 9.58 | 97 | 149529 | 123109 | 64225997 |
Blood urea increased | 80.09 | 9.58 | 255 | 149371 | 43898 | 64305208 |
Drug intolerance | 79.60 | 9.58 | 201 | 149425 | 187791 | 64161315 |
Toxicity to various agents | 77.18 | 9.58 | 510 | 149116 | 363003 | 63986103 |
Alopecia | 76.66 | 9.58 | 169 | 149457 | 165521 | 64183585 |
Acute kidney injury | 76.34 | 9.58 | 1464 | 148162 | 447776 | 63901330 |
Gastrointestinal haemorrhage | 75.03 | 9.58 | 545 | 149081 | 131767 | 64217339 |
Therapeutic product effect incomplete | 74.46 | 9.58 | 78 | 149548 | 103404 | 64245702 |
Pulmonary arterial hypertension | 73.53 | 9.58 | 174 | 149452 | 25193 | 64323913 |
Ascites | 72.75 | 9.58 | 311 | 149315 | 61690 | 64287416 |
Pneumonia aspiration | 72.42 | 9.58 | 301 | 149325 | 58970 | 64290136 |
International normalised ratio increased | 71.54 | 9.58 | 368 | 149258 | 78799 | 64270307 |
Product use issue | 70.80 | 9.58 | 154 | 149472 | 151561 | 64197545 |
Lower respiratory tract infection | 70.72 | 9.58 | 69 | 149557 | 94545 | 64254561 |
Injection site pain | 70.48 | 9.58 | 93 | 149533 | 111315 | 64237791 |
Glossodynia | 70.24 | 9.58 | 31 | 149595 | 64665 | 64284441 |
Pain | 69.45 | 9.58 | 887 | 148739 | 552624 | 63796482 |
Duodenal ulcer perforation | 67.48 | 9.58 | 3 | 149623 | 34622 | 64314484 |
Haemoglobin decreased | 64.37 | 9.58 | 714 | 148912 | 194349 | 64154757 |
Pleural effusion | 63.73 | 9.58 | 507 | 149119 | 126052 | 64223054 |
White blood cell count decreased | 63.16 | 9.58 | 601 | 149025 | 157236 | 64191870 |
Nasopharyngitis | 62.86 | 9.58 | 238 | 149388 | 195835 | 64153271 |
Glaucoma | 62.04 | 9.58 | 125 | 149501 | 16223 | 64332883 |
Fluid retention | 60.93 | 9.58 | 287 | 149339 | 59319 | 64289787 |
Plasma cell myeloma | 60.27 | 9.58 | 239 | 149387 | 45836 | 64303270 |
Drug hypersensitivity | 59.79 | 9.58 | 316 | 149310 | 237499 | 64111607 |
Helicobacter infection | 59.39 | 9.58 | 9 | 149617 | 38353 | 64310753 |
Mental status changes | 57.84 | 9.58 | 288 | 149338 | 60874 | 64288232 |
Incision site pain | 56.74 | 9.58 | 48 | 149578 | 2606 | 64346500 |
Pulmonary oedema | 56.00 | 9.58 | 343 | 149283 | 78331 | 64270775 |
Febrile neutropenia | 54.83 | 9.58 | 671 | 148955 | 186986 | 64162120 |
Infusion related reaction | 54.43 | 9.58 | 197 | 149429 | 164270 | 64184836 |
Treatment failure | 54.14 | 9.58 | 119 | 149507 | 116697 | 64232409 |
Cardiac arrest | 53.62 | 9.58 | 570 | 149056 | 153494 | 64195612 |
Blood bilirubin increased | 52.31 | 9.58 | 268 | 149358 | 57285 | 64291821 |
Dyspnoea | 52.26 | 9.58 | 2099 | 147527 | 716575 | 63632531 |
Appendicitis | 51.79 | 9.58 | 104 | 149522 | 13465 | 64335641 |
Tachypnoea | 51.46 | 9.58 | 157 | 149469 | 26414 | 64322692 |
Sopor | 50.71 | 9.58 | 5 | 149621 | 29656 | 64319450 |
Hypoglycaemia | 50.21 | 9.58 | 369 | 149257 | 89523 | 64259583 |
Muscle injury | 49.29 | 9.58 | 3 | 149623 | 26434 | 64322672 |
Injection site bruising | 48.99 | 9.58 | 12 | 149614 | 36361 | 64312745 |
Oedema | 48.31 | 9.58 | 372 | 149254 | 91563 | 64257543 |
Hyponatraemia | 47.11 | 9.58 | 539 | 149087 | 147800 | 64201306 |
Intentional self-injury | 46.88 | 9.58 | 6 | 149620 | 29038 | 64320068 |
Product use in unapproved indication | 46.45 | 9.58 | 231 | 149395 | 176387 | 64172719 |
Abdominal distension | 45.31 | 9.58 | 379 | 149247 | 95615 | 64253491 |
Psoriasis | 44.18 | 9.58 | 61 | 149565 | 71642 | 64277464 |
Multiple organ dysfunction syndrome | 44.00 | 9.58 | 393 | 149233 | 101020 | 64248086 |
Irritable bowel syndrome | 43.67 | 9.58 | 16 | 149610 | 37353 | 64311753 |
Asthenia | 43.53 | 9.58 | 1300 | 148326 | 426744 | 63922362 |
Intentional product use issue | 43.49 | 9.58 | 98 | 149528 | 95266 | 64253840 |
Chronic obstructive pulmonary disease | 43.37 | 9.58 | 298 | 149328 | 70750 | 64278356 |
Injection site swelling | 43.05 | 9.58 | 21 | 149605 | 41332 | 64307774 |
Rash | 42.65 | 9.58 | 778 | 148848 | 457771 | 63891335 |
Drug reaction with eosinophilia and systemic symptoms | 42.32 | 9.58 | 38 | 149588 | 54179 | 64294927 |
Gastrooesophageal reflux disease | 41.79 | 9.58 | 333 | 149293 | 82810 | 64266296 |
Suicidal ideation | 41.62 | 9.58 | 56 | 149570 | 66486 | 64282620 |
Hypersensitivity | 41.43 | 9.58 | 276 | 149350 | 196176 | 64152930 |
PO2 increased | 40.43 | 9.58 | 31 | 149595 | 1461 | 64347645 |
Hypernatraemia | 40.20 | 9.58 | 88 | 149538 | 12101 | 64337005 |
Atrial flutter | 39.88 | 9.58 | 117 | 149509 | 19263 | 64329843 |
Abdominal discomfort | 39.53 | 9.58 | 254 | 149372 | 182068 | 64167038 |
Discomfort | 39.47 | 9.58 | 80 | 149546 | 80798 | 64268308 |
Atelectasis | 39.40 | 9.58 | 146 | 149480 | 27120 | 64321986 |
Metabolic alkalosis | 39.22 | 9.58 | 47 | 149579 | 3881 | 64345225 |
Headache | 39.03 | 9.58 | 933 | 148693 | 528534 | 63820572 |
Injection site erythema | 39.02 | 9.58 | 65 | 149561 | 70735 | 64278371 |
Ventricular tachycardia | 38.75 | 9.58 | 170 | 149456 | 34095 | 64315011 |
Blood pressure fluctuation | 38.55 | 9.58 | 38 | 149588 | 51833 | 64297273 |
Folliculitis | 38.46 | 9.58 | 11 | 149615 | 30066 | 64319040 |
C-reactive protein abnormal | 38.32 | 9.58 | 10 | 149616 | 29037 | 64320069 |
Bronchitis | 38.13 | 9.58 | 403 | 149223 | 108340 | 64240766 |
Synovitis | 38.11 | 9.58 | 111 | 149515 | 98979 | 64250127 |
Toxic epidermal necrolysis | 38.01 | 9.58 | 179 | 149447 | 36987 | 64312119 |
Impaired healing | 37.71 | 9.58 | 51 | 149575 | 60422 | 64288684 |
Diverticulitis | 37.33 | 9.58 | 183 | 149443 | 38435 | 64310671 |
Non-cardiogenic pulmonary oedema | 37.26 | 9.58 | 28 | 149598 | 1280 | 64347826 |
Therapeutic response decreased | 36.79 | 9.58 | 40 | 149586 | 52148 | 64296958 |
Ill-defined disorder | 36.68 | 9.58 | 29 | 149597 | 44023 | 64305083 |
Hepatic enzyme increased | 36.47 | 9.58 | 166 | 149460 | 129777 | 64219329 |
Arthritis | 35.92 | 9.58 | 89 | 149537 | 83725 | 64265381 |
Anaemia | 35.79 | 9.58 | 1140 | 148486 | 377540 | 63971566 |
Administration site extravasation | 35.46 | 9.58 | 25 | 149601 | 1034 | 64348072 |
Spinal muscular atrophy | 35.17 | 9.58 | 16 | 149610 | 278 | 64348828 |
Renal failure | 34.55 | 9.58 | 603 | 149023 | 181085 | 64168021 |
Psoriatic arthropathy | 34.18 | 9.58 | 30 | 149596 | 43251 | 64305855 |
Lung consolidation | 33.94 | 9.58 | 63 | 149563 | 7695 | 64341411 |
Hypomagnesaemia | 33.93 | 9.58 | 174 | 149452 | 37202 | 64311904 |
Cardiac failure | 33.87 | 9.58 | 462 | 149164 | 131911 | 64217195 |
Serotonin syndrome | 33.81 | 9.58 | 25 | 149601 | 39257 | 64309849 |
Platelet count decreased | 32.75 | 9.58 | 559 | 149067 | 167152 | 64181954 |
Renal ischaemia | 32.68 | 9.58 | 24 | 149602 | 1059 | 64348047 |
Injection site reaction | 32.64 | 9.58 | 36 | 149590 | 46628 | 64302478 |
Encephalopathy | 32.58 | 9.58 | 241 | 149385 | 58578 | 64290528 |
Diabetes insipidus | 32.50 | 9.58 | 46 | 149580 | 4475 | 64344631 |
Deep vein thrombosis | 32.40 | 9.58 | 380 | 149246 | 104802 | 64244304 |
Red blood cell sedimentation rate increased | 32.30 | 9.58 | 16 | 149610 | 31219 | 64317887 |
Inappropriate schedule of product administration | 32.23 | 9.58 | 108 | 149518 | 92178 | 64256928 |
Ventricular fibrillation | 32.19 | 9.58 | 125 | 149501 | 23735 | 64325371 |
Cardiomegaly | 31.89 | 9.58 | 124 | 149502 | 23560 | 64325546 |
Cytomegalovirus infection | 31.60 | 9.58 | 24 | 149602 | 37175 | 64311931 |
Diaphragmatic spasm | 31.57 | 9.58 | 11 | 149615 | 90 | 64349016 |
Neutrophil count decreased | 31.37 | 9.58 | 295 | 149331 | 76901 | 64272205 |
PCO2 increased | 31.30 | 9.58 | 28 | 149598 | 1639 | 64347467 |
Pulse absent | 31.12 | 9.58 | 66 | 149560 | 8880 | 64340226 |
Loss of personal independence in daily activities | 31.00 | 9.58 | 77 | 149549 | 72377 | 64276729 |
Calcium deficiency | 30.87 | 9.58 | 20 | 149606 | 718 | 64348388 |
Blood magnesium decreased | 30.60 | 9.58 | 86 | 149540 | 13819 | 64335287 |
Cardiac dysfunction | 29.12 | 9.58 | 36 | 149590 | 3070 | 64346036 |
Electrolyte imbalance | 28.36 | 9.58 | 125 | 149501 | 25118 | 64323988 |
Pregnancy | 27.87 | 9.58 | 7 | 149619 | 20858 | 64328248 |
Completed suicide | 27.52 | 9.58 | 361 | 149265 | 224053 | 64125053 |
Blood potassium increased | 27.20 | 9.58 | 126 | 149500 | 25854 | 64323252 |
Bacteraemia | 27.07 | 9.58 | 129 | 149497 | 26782 | 64322324 |
Blood creatinine increased | 27.02 | 9.58 | 454 | 149172 | 135328 | 64213778 |
Foetal death | 27.01 | 9.58 | 49 | 149577 | 5881 | 64343225 |
Mobility decreased | 26.96 | 9.58 | 105 | 149521 | 85735 | 64263371 |
Faecal volume decreased | 26.78 | 9.58 | 11 | 149615 | 147 | 64348959 |
Blood albumin decreased | 26.50 | 9.58 | 108 | 149518 | 20965 | 64328141 |
Aspartate aminotransferase increased | 26.25 | 9.58 | 407 | 149219 | 119381 | 64229725 |
Sedation | 25.82 | 9.58 | 35 | 149591 | 41427 | 64307679 |
Transfusion | 25.70 | 9.58 | 96 | 149530 | 17898 | 64331208 |
Interstitial lung disease | 25.58 | 9.58 | 128 | 149498 | 97604 | 64251502 |
Swelling | 25.47 | 9.58 | 243 | 149383 | 159975 | 64189131 |
Constipation | 25.31 | 9.58 | 704 | 148922 | 228633 | 64120473 |
Multimorbidity | 25.20 | 9.58 | 20 | 149606 | 992 | 64348114 |
Brain natriuretic peptide increased | 25.05 | 9.58 | 55 | 149571 | 7578 | 64341528 |
Cor pulmonale | 24.92 | 9.58 | 27 | 149599 | 1998 | 64347108 |
Soft tissue mass | 24.88 | 9.58 | 19 | 149607 | 890 | 64348216 |
Blood alkaline phosphatase increased | 24.86 | 9.58 | 219 | 149407 | 56060 | 64293046 |
Full blood count decreased | 24.75 | 9.58 | 111 | 149515 | 22471 | 64326635 |
Sinusitis | 24.63 | 9.58 | 218 | 149408 | 145710 | 64203396 |
Failure to thrive | 24.54 | 9.58 | 66 | 149560 | 10338 | 64338768 |
Osteonecrosis of jaw | 24.41 | 9.58 | 34 | 149592 | 39791 | 64309315 |
Sleep disorder | 24.35 | 9.58 | 65 | 149561 | 59644 | 64289462 |
Intentional product misuse | 24.30 | 9.58 | 86 | 149540 | 72209 | 64276897 |
Urine chloride decreased | 24.25 | 9.58 | 9 | 149617 | 90 | 64349016 |
Suicide attempt | 24.18 | 9.58 | 84 | 149542 | 70923 | 64278183 |
Depressed mood | 24.17 | 9.58 | 36 | 149590 | 40976 | 64308130 |
Tachycardia | 23.46 | 9.58 | 482 | 149144 | 149097 | 64200009 |
Wrong technique in product usage process | 23.40 | 9.58 | 75 | 149551 | 64899 | 64284207 |
Malnutrition | 23.25 | 9.58 | 97 | 149529 | 19028 | 64330078 |
Abortion spontaneous | 22.96 | 9.58 | 15 | 149611 | 25128 | 64323978 |
Blood glucose increased | 22.95 | 9.58 | 337 | 149289 | 97736 | 64251370 |
Hepatocellular injury | 22.71 | 9.58 | 44 | 149582 | 45191 | 64303915 |
Immune effector cell-associated neurotoxicity syndrome | 22.62 | 9.58 | 29 | 149597 | 2566 | 64346540 |
Vomiting | 22.57 | 9.58 | 1525 | 148101 | 549592 | 63799514 |
Generalised oedema | 22.48 | 9.58 | 102 | 149524 | 20751 | 64328355 |
Infection | 22.44 | 9.58 | 298 | 149328 | 184582 | 64164524 |
Inflammation | 22.40 | 9.58 | 77 | 149549 | 65223 | 64283883 |
Cardiac failure acute | 22.36 | 9.58 | 86 | 149540 | 16258 | 64332848 |
Ileus | 22.31 | 9.58 | 109 | 149517 | 22857 | 64326249 |
Respiratory tract infection bacterial | 22.08 | 9.58 | 17 | 149609 | 806 | 64348300 |
Vertigo | 22.04 | 9.58 | 67 | 149559 | 58944 | 64290162 |
Urticaria | 21.92 | 9.58 | 227 | 149399 | 147090 | 64202016 |
Chills | 21.75 | 9.58 | 443 | 149183 | 136821 | 64212285 |
Thrombocytopenia | 21.69 | 9.58 | 676 | 148950 | 223125 | 64125981 |
Hypovolaemia | 21.61 | 9.58 | 82 | 149544 | 15404 | 64333702 |
Haematocrit decreased | 21.28 | 9.58 | 207 | 149419 | 54448 | 64294658 |
Oxygen consumption increased | 21.05 | 9.58 | 38 | 149588 | 4543 | 64344563 |
Catheter management | 21.03 | 9.58 | 32 | 149594 | 3323 | 64345783 |
Peritonitis bacterial | 20.96 | 9.58 | 57 | 149569 | 8986 | 64340120 |
Coma | 20.87 | 9.58 | 302 | 149324 | 87313 | 64261793 |
Respiratory distress | 20.77 | 9.58 | 199 | 149427 | 52132 | 64296974 |
Injection site pruritus | 20.59 | 9.58 | 35 | 149591 | 37791 | 64311315 |
Drug resistance | 20.50 | 9.58 | 31 | 149595 | 35071 | 64314035 |
Septic shock | 20.41 | 9.58 | 351 | 149275 | 105086 | 64244020 |
Product substitution issue | 20.28 | 9.58 | 8 | 149618 | 17853 | 64331253 |
Lung infiltration | 20.19 | 9.58 | 99 | 149527 | 20790 | 64328316 |
Small intestinal obstruction | 20.19 | 9.58 | 108 | 149518 | 23465 | 64325641 |
Tendonitis | 20.07 | 9.58 | 11 | 149615 | 20271 | 64328835 |
Hyperglycaemia | 20.00 | 9.58 | 223 | 149403 | 60745 | 64288361 |
Urinary tract infection | 19.98 | 9.58 | 690 | 148936 | 230906 | 64118200 |
Acute left ventricular failure | 19.76 | 9.58 | 20 | 149606 | 1367 | 64347739 |
Blood pH decreased | 19.57 | 9.58 | 36 | 149590 | 4366 | 64344740 |
Granulocytopenia | 19.57 | 9.58 | 61 | 149565 | 10379 | 64338727 |
Rheumatoid nodule | 19.51 | 9.58 | 3 | 149623 | 12648 | 64336458 |
Blood chloride decreased | 19.50 | 9.58 | 49 | 149577 | 7367 | 64341739 |
Herpes zoster | 19.44 | 9.58 | 106 | 149520 | 79081 | 64270025 |
Supraventricular tachycardia | 19.28 | 9.58 | 91 | 149535 | 18816 | 64330290 |
Alkalosis | 18.82 | 9.58 | 12 | 149614 | 419 | 64348687 |
Product storage error | 18.72 | 9.58 | 4 | 149622 | 13314 | 64335792 |
Knee arthroplasty | 18.69 | 9.58 | 21 | 149605 | 26978 | 64322128 |
Oropharyngeal pain | 18.64 | 9.58 | 125 | 149501 | 88742 | 64260364 |
Oesophageal perforation | 18.59 | 9.58 | 17 | 149609 | 1024 | 64348082 |
Insomnia | 18.54 | 9.58 | 335 | 149291 | 197501 | 64151605 |
Blood bicarbonate decreased | 18.41 | 9.58 | 37 | 149589 | 4792 | 64344314 |
Aggression | 18.35 | 9.58 | 51 | 149575 | 46181 | 64302925 |
Abdominal pain | 18.08 | 9.58 | 892 | 148734 | 311483 | 64037623 |
Overdose | 18.00 | 9.58 | 261 | 149365 | 159305 | 64189801 |
Posterior reversible encephalopathy syndrome | 18.00 | 9.58 | 16 | 149610 | 22930 | 64326176 |
Gastrointestinal disorder | 17.92 | 9.58 | 128 | 149498 | 89581 | 64259525 |
Burkholderia test positive | 17.85 | 9.58 | 13 | 149613 | 566 | 64348540 |
Hip arthroplasty | 17.85 | 9.58 | 14 | 149612 | 21337 | 64327769 |
Catheter site extravasation | 17.81 | 9.58 | 11 | 149615 | 363 | 64348743 |
Coagulopathy | 17.79 | 9.58 | 131 | 149495 | 31789 | 64317317 |
Prothrombin time prolonged | 17.72 | 9.58 | 78 | 149548 | 15663 | 64333443 |
Maternal exposure during pregnancy | 17.64 | 9.58 | 140 | 149486 | 95744 | 64253362 |
Electrocardiogram T wave peaked | 17.52 | 9.58 | 15 | 149611 | 828 | 64348278 |
Diarrhoea | 17.49 | 9.58 | 1923 | 147703 | 720781 | 63628325 |
Drug eruption | 17.41 | 9.58 | 36 | 149590 | 36100 | 64313006 |
Lymphocyte count decreased | 17.27 | 9.58 | 157 | 149469 | 40542 | 64308564 |
Obstructive airways disorder | 17.21 | 9.58 | 17 | 149609 | 23168 | 64325938 |
Pneumococcal sepsis | 17.13 | 9.58 | 18 | 149608 | 1286 | 64347820 |
Clostridium difficile colitis | 17.09 | 9.58 | 115 | 149511 | 27108 | 64321998 |
Asthma | 17.08 | 9.58 | 140 | 149486 | 95085 | 64254021 |
Syncope | 16.85 | 9.58 | 482 | 149144 | 157153 | 64191953 |
Hepatitis | 16.84 | 9.58 | 52 | 149574 | 45530 | 64303576 |
Red blood cells urine positive | 16.70 | 9.58 | 34 | 149592 | 4444 | 64344662 |
Blood pressure decreased | 16.69 | 9.58 | 287 | 149339 | 85912 | 64263194 |
Mental status changes postoperative | 16.66 | 9.58 | 8 | 149618 | 158 | 64348948 |
Torsade de pointes | 16.58 | 9.58 | 82 | 149544 | 17281 | 64331825 |
Muscle spasticity | 16.55 | 9.58 | 9 | 149617 | 16660 | 64332446 |
Blood pressure increased | 16.54 | 9.58 | 291 | 149335 | 172261 | 64176845 |
Cellulitis | 16.43 | 9.58 | 307 | 149319 | 93350 | 64255756 |
Unresponsive to stimuli | 16.38 | 9.58 | 184 | 149442 | 50209 | 64298897 |
Dementia | 16.36 | 9.58 | 93 | 149533 | 20673 | 64328433 |
Dyspnoea exertional | 16.33 | 9.58 | 251 | 149375 | 73479 | 64275627 |
Activated partial thromboplastin time prolonged | 16.33 | 9.58 | 66 | 149560 | 12765 | 64336341 |
Renal injury | 16.28 | 9.58 | 75 | 149551 | 15354 | 64333752 |
Osmotic demyelination syndrome | 16.18 | 9.58 | 17 | 149609 | 1214 | 64347892 |
Condition aggravated | 16.11 | 9.58 | 703 | 148923 | 371723 | 63977383 |
Body temperature decreased | 16.03 | 9.58 | 22 | 149604 | 25906 | 64323200 |
Hyperpyrexia | 16.00 | 9.58 | 36 | 149590 | 5041 | 64344065 |
Osteoarthritis | 15.98 | 9.58 | 84 | 149542 | 63252 | 64285854 |
Haematotoxicity | 15.97 | 9.58 | 5 | 149621 | 12891 | 64336215 |
Drug interaction | 15.97 | 9.58 | 682 | 148944 | 361401 | 63987705 |
Epididymitis | 15.92 | 9.58 | 20 | 149606 | 1734 | 64347372 |
Haemoptysis | 15.90 | 9.58 | 179 | 149447 | 48869 | 64300237 |
Pneumonia staphylococcal | 15.90 | 9.58 | 33 | 149593 | 4373 | 64344733 |
Cardiomyopathy | 15.85 | 9.58 | 107 | 149519 | 25249 | 64323857 |
Drug chemical incompatibility | 15.74 | 9.58 | 6 | 149620 | 65 | 64349041 |
Normal newborn | 15.70 | 9.58 | 38 | 149588 | 5579 | 64343527 |
Fatigue | 15.69 | 9.58 | 1510 | 148116 | 747220 | 63601886 |
Grip strength decreased | 15.53 | 9.58 | 4 | 149622 | 11720 | 64337386 |
Anhedonia | 15.49 | 9.58 | 68 | 149558 | 13638 | 64335468 |
Urine sodium decreased | 15.43 | 9.58 | 9 | 149617 | 267 | 64348839 |
Renal tubular acidosis | 15.36 | 9.58 | 26 | 149600 | 2953 | 64346153 |
Shoshin beriberi | 15.34 | 9.58 | 6 | 149620 | 70 | 64349036 |
Device issue | 15.26 | 9.58 | 18 | 149608 | 22630 | 64326476 |
Blood pressure systolic increased | 15.20 | 9.58 | 61 | 149565 | 49392 | 64299714 |
Hypoalbuminaemia | 15.16 | 9.58 | 81 | 149545 | 17593 | 64331513 |
Disturbance in attention | 15.08 | 9.58 | 47 | 149579 | 41027 | 64308079 |
Pantoea agglomerans infection | 15.04 | 9.58 | 6 | 149620 | 74 | 64349032 |
Resuscitation | 14.94 | 9.58 | 21 | 149605 | 2030 | 64347076 |
Oesophageal pain | 14.91 | 9.58 | 27 | 149599 | 3236 | 64345870 |
Accidental exposure to product | 14.71 | 9.58 | 24 | 149602 | 26340 | 64322766 |
Tumour lysis syndrome | 14.62 | 9.58 | 86 | 149540 | 19354 | 64329752 |
Disability | 14.58 | 9.58 | 5 | 149621 | 12167 | 64336939 |
Unevaluable event | 14.49 | 9.58 | 180 | 149446 | 50309 | 64298797 |
Device related infection | 14.48 | 9.58 | 121 | 149505 | 30505 | 64318601 |
Arrhythmia | 14.45 | 9.58 | 187 | 149439 | 52757 | 64296349 |
Oxygen saturation abnormal | 14.39 | 9.58 | 28 | 149598 | 3543 | 64345563 |
Polyneuropathy | 14.30 | 9.58 | 15 | 149611 | 19879 | 64329227 |
Middle insomnia | 14.24 | 9.58 | 6 | 149620 | 12871 | 64336235 |
Paraesthesia | 14.16 | 9.58 | 223 | 149403 | 134299 | 64214807 |
Cyanosis | 14.15 | 9.58 | 94 | 149532 | 22061 | 64327045 |
Joint stiffness | 14.05 | 9.58 | 31 | 149595 | 30373 | 64318733 |
Familial periodic paralysis | 13.97 | 9.58 | 7 | 149619 | 152 | 64348954 |
Granulocyte count decreased | 13.96 | 9.58 | 16 | 149610 | 1260 | 64347846 |
Blood pressure systolic abnormal | 13.95 | 9.58 | 3 | 149623 | 9939 | 64339167 |
Hepatotoxicity | 13.79 | 9.58 | 47 | 149579 | 39915 | 64309191 |
Chronic respiratory failure | 13.78 | 9.58 | 23 | 149603 | 2583 | 64346523 |
Skin dystrophy | 13.74 | 9.58 | 5 | 149621 | 47 | 64349059 |
Cardiovascular insufficiency | 13.66 | 9.58 | 23 | 149603 | 2601 | 64346505 |
Congestive hepatopathy | 13.46 | 9.58 | 29 | 149597 | 3944 | 64345162 |
Tonsillar haemorrhage | 13.43 | 9.58 | 8 | 149618 | 247 | 64348859 |
Poor venous access | 13.39 | 9.58 | 6 | 149620 | 12411 | 64336695 |
Oesophagitis | 13.35 | 9.58 | 91 | 149535 | 21539 | 64327567 |
Gait disturbance | 13.29 | 9.58 | 301 | 149325 | 171854 | 64177252 |
Rales | 13.20 | 9.58 | 70 | 149556 | 15159 | 64333947 |
Blister | 13.20 | 9.58 | 122 | 149504 | 80845 | 64268261 |
Oxygen therapy | 13.16 | 9.58 | 21 | 149605 | 2272 | 64346834 |
Gastric ischaemia | 13.13 | 9.58 | 3 | 149623 | 3 | 64349103 |
Electrocardiogram abnormal | 13.11 | 9.58 | 64 | 149562 | 13417 | 64335689 |
Bradycardia | 13.05 | 9.58 | 363 | 149263 | 117856 | 64231250 |
Oesophageal spasm | 12.97 | 9.58 | 22 | 149604 | 2503 | 64346603 |
Left ventricular failure | 12.95 | 9.58 | 46 | 149580 | 8371 | 64340735 |
Acne | 12.89 | 9.58 | 21 | 149605 | 23060 | 64326046 |
Sputum increased | 12.86 | 9.58 | 27 | 149599 | 3608 | 64345498 |
Cortical visual impairment | 12.84 | 9.58 | 4 | 149622 | 22 | 64349084 |
Pulmonary arterial pressure increased | 12.77 | 9.58 | 29 | 149597 | 4087 | 64345019 |
Impaired work ability | 12.69 | 9.58 | 10 | 149616 | 15209 | 64333897 |
Hyperaldosteronism | 12.67 | 9.58 | 9 | 149617 | 377 | 64348729 |
Decubitus ulcer | 12.64 | 9.58 | 63 | 149563 | 13316 | 64335790 |
Hypophagia | 12.62 | 9.58 | 144 | 149482 | 39443 | 64309663 |
Electrocardiogram U wave present | 12.61 | 9.58 | 6 | 149620 | 116 | 64348990 |
Cardioactive drug level increased | 12.56 | 9.58 | 26 | 149600 | 3439 | 64345667 |
Pain in extremity | 12.51 | 9.58 | 575 | 149051 | 302510 | 64046596 |
Blood pressure diastolic abnormal | 12.48 | 9.58 | 6 | 149620 | 11911 | 64337195 |
Multiple sclerosis relapse | 12.48 | 9.58 | 51 | 149575 | 41084 | 64308022 |
Metabolic encephalopathy | 12.47 | 9.58 | 44 | 149582 | 7981 | 64341125 |
Vascular device infection | 12.42 | 9.58 | 37 | 149589 | 6143 | 64342963 |
Hot flush | 12.41 | 9.58 | 60 | 149566 | 46175 | 64302931 |
Injection site warmth | 12.34 | 9.58 | 8 | 149618 | 13454 | 64335652 |
Injection site rash | 12.32 | 9.58 | 11 | 149615 | 15731 | 64333375 |
Confusion postoperative | 12.27 | 9.58 | 7 | 149619 | 199 | 64348907 |
Alanine aminotransferase increased | 12.17 | 9.58 | 415 | 149211 | 138616 | 64210490 |
Pericardial effusion | 12.16 | 9.58 | 142 | 149484 | 39112 | 64309994 |
Hyponatraemic encephalopathy | 12.14 | 9.58 | 8 | 149618 | 296 | 64348810 |
Disease complication | 12.13 | 9.58 | 29 | 149597 | 4226 | 64344880 |
Pancytopenia | 12.11 | 9.58 | 426 | 149200 | 142883 | 64206223 |
Nail dystrophy | 12.09 | 9.58 | 12 | 149614 | 801 | 64348305 |
Myalgia | 12.05 | 9.58 | 278 | 149348 | 158339 | 64190767 |
Epstein-Barr virus infection | 12.03 | 9.58 | 7 | 149619 | 12481 | 64336625 |
Miosis | 12.00 | 9.58 | 8 | 149618 | 13258 | 64335848 |
Stoma closure | 11.95 | 9.58 | 6 | 149620 | 131 | 64348975 |
Abortion incomplete complicated | 11.92 | 9.58 | 3 | 149623 | 6 | 64349100 |
Lactobacillus test positive | 11.78 | 9.58 | 4 | 149622 | 30 | 64349076 |
Akathisia | 11.75 | 9.58 | 6 | 149620 | 11504 | 64337602 |
Biliary obstruction | 11.74 | 9.58 | 27 | 149599 | 3837 | 64345269 |
Thyroid disorder | 11.72 | 9.58 | 56 | 149570 | 11636 | 64337470 |
Extrapyramidal disorder | 11.68 | 9.58 | 17 | 149609 | 19535 | 64329571 |
Photosensitivity reaction | 11.66 | 9.58 | 15 | 149611 | 18158 | 64330948 |
Mood swings | 11.65 | 9.58 | 14 | 149612 | 17454 | 64331652 |
Electrocardiogram T wave amplitude decreased | 11.63 | 9.58 | 10 | 149616 | 555 | 64348551 |
Motor neurone disease | 11.63 | 9.58 | 9 | 149617 | 430 | 64348676 |
Blood potassium abnormal | 11.51 | 9.58 | 21 | 149605 | 2531 | 64346575 |
Altered state of consciousness | 11.49 | 9.58 | 47 | 149579 | 37855 | 64311251 |
Vocal cord paralysis | 11.43 | 9.58 | 19 | 149607 | 2127 | 64346979 |
Skin disorder | 11.39 | 9.58 | 30 | 149596 | 27650 | 64321456 |
Malaise | 11.35 | 9.58 | 779 | 148847 | 395468 | 63953638 |
Foot deformity | 11.25 | 9.58 | 13 | 149613 | 16491 | 64332615 |
Central nervous system injury | 11.21 | 9.58 | 6 | 149620 | 150 | 64348956 |
Schizophrenia | 11.13 | 9.58 | 6 | 149620 | 11162 | 64337944 |
Carbon dioxide increased | 11.12 | 9.58 | 18 | 149608 | 1971 | 64347135 |
Splenic injury | 11.09 | 9.58 | 7 | 149619 | 240 | 64348866 |
Lymphoedema | 11.09 | 9.58 | 49 | 149577 | 9856 | 64339250 |
Injection site haemorrhage | 11.02 | 9.58 | 25 | 149601 | 24253 | 64324853 |
Ventricular extrasystoles | 10.97 | 9.58 | 74 | 149552 | 17455 | 64331651 |
Potassium wasting nephropathy | 10.93 | 9.58 | 6 | 149620 | 158 | 64348948 |
Gout | 10.88 | 9.58 | 86 | 149540 | 21327 | 64327779 |
HLA-B*27 positive | 10.88 | 9.58 | 5 | 149621 | 89 | 64349017 |
Left ventricular dysfunction | 10.87 | 9.58 | 72 | 149554 | 16882 | 64332224 |
Right ventricular dilatation | 10.83 | 9.58 | 15 | 149611 | 1430 | 64347676 |
Basal cell carcinoma | 10.82 | 9.58 | 36 | 149590 | 30802 | 64318304 |
Substance abuse | 10.82 | 9.58 | 4 | 149622 | 9288 | 64339818 |
Arrhythmia supraventricular | 10.81 | 9.58 | 17 | 149609 | 1816 | 64347290 |
Cognitive disorder | 10.81 | 9.58 | 79 | 149547 | 55008 | 64294098 |
Multiple drug therapy | 10.74 | 9.58 | 19 | 149607 | 2235 | 64346871 |
Oral herpes | 10.73 | 9.58 | 22 | 149604 | 22130 | 64326976 |
Blood cholesterol increased | 10.71 | 9.58 | 70 | 149556 | 49996 | 64299110 |
Lower gastrointestinal haemorrhage | 10.70 | 9.58 | 62 | 149564 | 13877 | 64335229 |
Lip erosion | 10.69 | 9.58 | 14 | 149612 | 1265 | 64347841 |
Weight increased | 10.65 | 9.58 | 396 | 149230 | 212952 | 64136154 |
Haemodialysis | 10.64 | 9.58 | 72 | 149554 | 17005 | 64332101 |
Blood aldosterone abnormal | 10.60 | 9.58 | 4 | 149622 | 42 | 64349064 |
Catheterisation cardiac | 10.59 | 9.58 | 30 | 149596 | 4843 | 64344263 |
Superinfection | 10.56 | 9.58 | 26 | 149600 | 3860 | 64345246 |
Extravasation | 10.53 | 9.58 | 23 | 149603 | 3157 | 64345949 |
Enterococcal bacteraemia | 10.53 | 9.58 | 20 | 149606 | 2485 | 64346621 |
Chronic kidney disease-mineral and bone disorder | 10.43 | 9.58 | 9 | 149617 | 502 | 64348604 |
Right atrial pressure increased | 10.38 | 9.58 | 7 | 149619 | 269 | 64348837 |
Poisoning | 10.37 | 9.58 | 22 | 149604 | 21857 | 64327249 |
Tuberculosis | 10.34 | 9.58 | 9 | 149617 | 13029 | 64336077 |
Vasoplegia syndrome | 10.31 | 9.58 | 21 | 149605 | 2746 | 64346360 |
Throat irritation | 10.28 | 9.58 | 40 | 149586 | 32671 | 64316435 |
Oxalosis | 10.26 | 9.58 | 5 | 149621 | 102 | 64349004 |
Bilirubin conjugated increased | 10.23 | 9.58 | 30 | 149596 | 4938 | 64344168 |
Occult blood positive | 10.22 | 9.58 | 35 | 149591 | 6252 | 64342854 |
Blood gases abnormal | 10.21 | 9.58 | 12 | 149614 | 971 | 64348135 |
Blood sodium decreased | 10.20 | 9.58 | 109 | 149517 | 29373 | 64319733 |
Therapeutic product effect prolonged | 10.19 | 9.58 | 9 | 149617 | 518 | 64348588 |
Encapsulating peritoneal sclerosis | 10.15 | 9.58 | 11 | 149615 | 814 | 64348292 |
Angioedema | 10.14 | 9.58 | 93 | 149533 | 61728 | 64287378 |
Compartment syndrome | 10.13 | 9.58 | 27 | 149599 | 4205 | 64344901 |
Hypercapnia | 10.13 | 9.58 | 40 | 149586 | 7654 | 64341452 |
Deposit eye | 10.13 | 9.58 | 4 | 149622 | 48 | 64349058 |
Dry eye | 10.10 | 9.58 | 34 | 149592 | 28985 | 64320121 |
Alveolar lung disease | 10.04 | 9.58 | 9 | 149617 | 528 | 64348578 |
Visual acuity reduced | 10.00 | 9.58 | 31 | 149595 | 27110 | 64321996 |
Hyperinsulinaemia | 9.99 | 9.58 | 6 | 149620 | 188 | 64348918 |
Paranoia | 9.98 | 9.58 | 14 | 149612 | 16338 | 64332768 |
Electrocardiogram P wave abnormal | 9.94 | 9.58 | 7 | 149619 | 289 | 64348817 |
Type IIa hyperlipidaemia | 9.93 | 9.58 | 6 | 149620 | 190 | 64348916 |
Increased bronchial secretion | 9.92 | 9.58 | 21 | 149605 | 2821 | 64346285 |
Frequent bowel movements | 9.90 | 9.58 | 17 | 149609 | 18288 | 64330818 |
Mania | 9.88 | 9.58 | 14 | 149612 | 16272 | 64332834 |
Azotaemia | 9.87 | 9.58 | 39 | 149587 | 7463 | 64341643 |
Sensory integrative dysfunction | 9.87 | 9.58 | 3 | 149623 | 15 | 64349091 |
Poisoning deliberate | 9.84 | 9.58 | 10 | 149616 | 13448 | 64335658 |
Arteriovenous malformation | 9.83 | 9.58 | 15 | 149611 | 1561 | 64347545 |
Vertebrobasilar insufficiency | 9.82 | 9.58 | 6 | 149620 | 194 | 64348912 |
Stomatitis | 9.82 | 9.58 | 187 | 149439 | 109418 | 64239688 |
Live birth | 9.81 | 9.58 | 7 | 149619 | 11197 | 64337909 |
Food allergy | 9.80 | 9.58 | 3 | 149623 | 7848 | 64341258 |
Protein urine present | 9.80 | 9.58 | 44 | 149582 | 8912 | 64340194 |
Dystonia | 9.77 | 9.58 | 18 | 149608 | 18847 | 64330259 |
Bezoar | 9.77 | 9.58 | 18 | 149608 | 2185 | 64346921 |
Atrioventricular block first degree | 9.76 | 9.58 | 50 | 149576 | 10684 | 64338422 |
Movement disorder | 9.71 | 9.58 | 23 | 149603 | 21977 | 64327129 |
Gastritis erosive | 9.65 | 9.58 | 46 | 149580 | 9549 | 64339557 |
Retroperitoneal haemorrhage | 9.64 | 9.58 | 29 | 149597 | 4839 | 64344267 |
Electrocardiogram QT prolonged | 9.64 | 9.58 | 247 | 149379 | 79201 | 64269905 |
Cardiomyopathy alcoholic | 9.64 | 9.58 | 4 | 149622 | 55 | 64349051 |
Neutrophil count increased | 9.63 | 9.58 | 95 | 149531 | 25079 | 64324027 |
Influenza like illness | 9.62 | 9.58 | 94 | 149532 | 61608 | 64287498 |
Mitral valve incompetence | 9.59 | 9.58 | 96 | 149530 | 25442 | 64323664 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hyperglycaemia | 32.07 | 29.88 | 12 | 282 | 80 | 84304 |
Source | Code | Description |
---|---|---|
ATC | B05CX01 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS IRRIGATING SOLUTIONS Other irrigating solutions |
ATC | C05BB56 | CARDIOVASCULAR SYSTEM VASOPROTECTIVES ANTIVARICOSE THERAPY Sclerosing agents for local injection |
ATC | V04CA02 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Tests for diabetes |
ATC | V06DC01 | VARIOUS GENERAL NUTRIENTS OTHER NUTRIENTS Carbohydrates |
CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
CHEBI has role | CHEBI:75772 | S. cerevisiae metabolites |
CHEBI has role | CHEBI:76971 | Escherichia coli metabolites |
CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
MeSH PA | D005421 | Flavoring Agents |
MeSH PA | D005503 | Food Additives |
MeSH PA | D013549 | Sweetening Agents |
CHEBI has role | CHEBI:78675 | fundamental metabolites |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Hypoglycemia | indication | 302866003 | DOID:9993 |
Species | Use | Relation |
---|---|---|
Cattle | Dehydration associated with diarrhea | Indication |
Cattle | Early treatment of scouring | Indication |
Cattle | Followup treatment following intravenous fluid therapy | Indication |
Product | Applicant | Ingredients |
---|---|---|
Re-Sorb, Vytrate | Zoetis Inc. | 6 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 11.87 | acidic |
pKa2 | 13.08 | acidic |
pKa3 | 13.91 | acidic |
None
None
None
ID | Source |
---|---|
4019541 | VUID |
N0000147647 | NUI |
D00009 | KEGG_DRUG |
77938-63-7 | SECONDARY_CAS_RN |
50-99-7 | SECONDARY_CAS_RN |
1299920 | RXNORM |
4017760 | VANDF |
4019541 | VANDF |
C0017725 | UMLSCUI |
CHEBI:4167 | CHEBI |
BGC | PDB_CHEM_ID |
CHEMBL1222250 | ChEMBL_ID |
CHEMBL1614854 | ChEMBL_ID |
D005947 | MESH_DESCRIPTOR_UI |
DB09341 | DRUGBANK_ID |
4536 | IUPHAR_LIGAND_ID |
5793 | PUBCHEM_CID |
DB01914 | DRUGBANK_ID |
11133 | MMSL |
4567 | MMSL |
4787 | MMSL |
71873 | MMSL |
71874 | MMSL |
9763 | MMSL |
d00595 | MMSL |
000915 | NDDF |
002597 | NDDF |
111138002 | SNOMEDCT_US |
67079006 | SNOMEDCT_US |
725859007 | SNOMEDCT_US |
768547002 | SNOMEDCT_US |
LX22YL083G | UNII |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-1290 | INJECTION, SOLUTION | 70 g | INTRAVENOUS | UNAPPROVED DRUG OTHER | 24 sections |
Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-1510 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | NDA | 24 sections |
MYOCARD-DX | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-1840 | INJECTION | 5 g | INTRAVENOUS | EXPORT ONLY | 20 sections |
MYOCARD-DX | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-1880 | INJECTION | 5 g | INTRAVENOUS | EXPORT ONLY | 20 sections |
Isolyte P in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-7730 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 23 sections |
Dextrose in Lactated Ringers | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-7751 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 22 sections |
Theophylline in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9554 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 27 sections |
Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9567 | INJECTION | 5 g | INTRAVENOUS | NDA | 19 sections |
Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9577 | INJECTION | 5 g | INTRAVENOUS | NDA | 19 sections |
Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9587 | INJECTION | 5 g | INTRAVENOUS | NDA | 19 sections |
Lidocaine Hydrochloride and Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9594 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 23 sections |
Lidocaine Hydrochloride and Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9598 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 23 sections |
DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0017 | INJECTION, SOLUTION | 50 g | INTRAVENOUS | NDA | 21 sections |
DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0023 | INJECTION, SOLUTION | 100 g | INTRAVENOUS | NDA | 21 sections |
DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0062 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0066 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0070 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0073 | INJECTION, SOLUTION | 2.50 g | INTRAVENOUS | NDA | 21 sections |
DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0074 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0077 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0078 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0081 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0082 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0085 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0089 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
Lactated Ringers and Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0338-0125 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 18 sections |
Dextrose and Electrolyte No. 48 | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0338-0143 | INJECTION | 5 g | INTRAVENOUS | NDA | 19 sections |
Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0551 | INJECTION | 5 g | INTRAVENOUS | NDA | 21 sections |
Potassium Chloride in Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0338-0603 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
Potassium Chloride in Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0338-0663 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |