glucose Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 845 | 492-61-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BA (Bioavailability) | 99 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Jan. 17, 1946 | FDA | B BRAUN |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Peritonitis bacterial | 2226.68 | 9.79 | 856 | 134403 | 8649 | 53205158 |
| Death | 1904.43 | 9.79 | 3308 | 131951 | 353924 | 52859883 |
| Peritonitis | 1623.20 | 9.79 | 882 | 134377 | 20805 | 53193002 |
| Fluid overload | 912.18 | 9.79 | 671 | 134588 | 27160 | 53186647 |
| Peritoneal dialysis complication | 845.85 | 9.79 | 305 | 134954 | 2528 | 53211279 |
| Drug ineffective | 522.52 | 9.79 | 794 | 134465 | 816451 | 52397356 |
| Rheumatoid arthritis | 489.55 | 9.79 | 101 | 135158 | 314430 | 52899377 |
| Sepsis | 280.91 | 9.79 | 913 | 134346 | 145516 | 53068291 |
| Bloody peritoneal effluent | 278.82 | 9.79 | 86 | 135173 | 409 | 53213398 |
| Cardiac failure congestive | 262.10 | 9.79 | 665 | 134594 | 92092 | 53121715 |
| Hypokalaemia | 245.18 | 9.79 | 665 | 134594 | 95852 | 53117955 |
| Myelosuppression | 244.78 | 9.79 | 226 | 135033 | 12602 | 53201205 |
| Ultrafiltration failure | 230.95 | 9.79 | 80 | 135179 | 581 | 53213226 |
| Fungal peritonitis | 227.14 | 9.79 | 86 | 135173 | 828 | 53212979 |
| Joint swelling | 222.86 | 9.79 | 162 | 135097 | 234476 | 52979331 |
| Contraindicated product administered | 207.69 | 9.79 | 45 | 135214 | 135584 | 53078223 |
| Hypotension | 195.63 | 9.79 | 1206 | 134053 | 252870 | 52960937 |
| Hand deformity | 195.35 | 9.79 | 4 | 135255 | 84845 | 53128962 |
| Dehydration | 195.17 | 9.79 | 895 | 134364 | 167515 | 53046292 |
| Alopecia | 185.14 | 9.79 | 193 | 135066 | 234390 | 52979417 |
| Systemic lupus erythematosus | 177.60 | 9.79 | 49 | 135210 | 125365 | 53088442 |
| Arthropathy | 168.15 | 9.79 | 74 | 135185 | 141379 | 53072428 |
| Arthralgia | 167.74 | 9.79 | 564 | 134695 | 439219 | 52774588 |
| Pneumonia | 167.13 | 9.79 | 1670 | 133589 | 405499 | 52808308 |
| Glossodynia | 164.69 | 9.79 | 28 | 135231 | 100263 | 53113544 |
| Blood potassium decreased | 153.70 | 9.79 | 326 | 134933 | 40134 | 53173673 |
| Cardiac arrest | 152.29 | 9.79 | 553 | 134706 | 93114 | 53120693 |
| Off label use | 148.88 | 9.79 | 654 | 134605 | 471558 | 52742249 |
| Therapeutic product effect decreased | 141.22 | 9.79 | 71 | 135188 | 125584 | 53088223 |
| Pain | 134.76 | 9.79 | 907 | 134352 | 587491 | 52626316 |
| Acute myocardial infarction | 127.64 | 9.79 | 269 | 134990 | 32966 | 53180841 |
| Drug intolerance | 123.30 | 9.79 | 207 | 135052 | 205286 | 53008521 |
| Catheter site infection | 121.46 | 9.79 | 101 | 135158 | 4891 | 53208916 |
| Abdominal distension | 120.43 | 9.79 | 460 | 134799 | 79330 | 53134477 |
| Product use issue | 117.94 | 9.79 | 108 | 135151 | 139476 | 53074331 |
| Hyperkalaemia | 115.52 | 9.79 | 351 | 134908 | 53905 | 53159902 |
| Colitis microscopic | 110.86 | 9.79 | 112 | 135147 | 6982 | 53206825 |
| Infusion related reaction | 110.29 | 9.79 | 140 | 135119 | 155817 | 53057990 |
| Fluid retention | 107.56 | 9.79 | 343 | 134916 | 54058 | 53159749 |
| Hypervolaemia | 105.91 | 9.79 | 67 | 135192 | 2106 | 53211701 |
| Diabetic foot | 104.37 | 9.79 | 61 | 135198 | 1657 | 53212150 |
| Respiratory failure | 103.12 | 9.79 | 516 | 134743 | 99996 | 53113811 |
| Rash | 102.35 | 9.79 | 687 | 134572 | 445504 | 52768303 |
| Pericarditis | 101.37 | 9.79 | 20 | 135239 | 64386 | 53149421 |
| Drug hypersensitivity | 101.00 | 9.79 | 340 | 134919 | 264902 | 52948905 |
| Cardio-respiratory arrest | 100.66 | 9.79 | 353 | 134906 | 58405 | 53155402 |
| Musculoskeletal stiffness | 100.06 | 9.79 | 99 | 135160 | 123269 | 53090538 |
| Peritoneal cloudy effluent | 100.01 | 9.79 | 35 | 135224 | 263 | 53213544 |
| Drug abuse | 99.73 | 9.79 | 22 | 135237 | 65504 | 53148303 |
| Lower respiratory tract infection | 98.38 | 9.79 | 54 | 135205 | 90927 | 53122880 |
| Pneumonia aspiration | 97.90 | 9.79 | 247 | 135012 | 34054 | 53179753 |
| Bone marrow failure | 96.77 | 9.79 | 227 | 135032 | 29888 | 53183919 |
| Wound | 92.43 | 9.79 | 59 | 135200 | 91498 | 53122309 |
| Cardiovascular disorder | 90.20 | 9.79 | 133 | 135126 | 12280 | 53201527 |
| Pulmonary oedema | 89.66 | 9.79 | 320 | 134939 | 53403 | 53160404 |
| Procedural pain | 87.82 | 9.79 | 144 | 135115 | 14573 | 53199234 |
| Pleural effusion | 87.53 | 9.79 | 450 | 134809 | 88129 | 53125678 |
| Myocardial infarction | 87.48 | 9.79 | 489 | 134770 | 98865 | 53114942 |
| Cerebrovascular accident | 86.94 | 9.79 | 509 | 134750 | 104665 | 53109142 |
| Disease complication | 85.89 | 9.79 | 69 | 135190 | 3181 | 53210626 |
| Hypoxia | 84.81 | 9.79 | 322 | 134937 | 55358 | 53158449 |
| Therapeutic product effect incomplete | 82.39 | 9.79 | 67 | 135192 | 91717 | 53122090 |
| Malnutrition | 81.41 | 9.79 | 140 | 135119 | 14731 | 53199076 |
| Gastrointestinal haemorrhage | 81.39 | 9.79 | 411 | 134848 | 79919 | 53133888 |
| Maternal exposure during pregnancy | 79.96 | 9.79 | 172 | 135087 | 155467 | 53058340 |
| Oedema peripheral | 79.94 | 9.79 | 721 | 134538 | 170066 | 53043741 |
| Multimorbidity | 78.05 | 9.79 | 38 | 135221 | 705 | 53213102 |
| Pulmonary hypertension | 74.58 | 9.79 | 236 | 135023 | 37034 | 53176773 |
| Hypersensitivity | 73.52 | 9.79 | 280 | 134979 | 210385 | 53003422 |
| Headache | 72.67 | 9.79 | 943 | 134316 | 535878 | 52677929 |
| Atrial fibrillation | 72.32 | 9.79 | 508 | 134751 | 111144 | 53102663 |
| Psoriasis | 71.63 | 9.79 | 69 | 135190 | 87020 | 53126787 |
| Cardiac failure | 71.28 | 9.79 | 416 | 134843 | 85428 | 53128379 |
| Helicobacter infection | 70.96 | 9.79 | 8 | 135251 | 39061 | 53174746 |
| Hypoglycaemia | 69.98 | 9.79 | 316 | 134943 | 58697 | 53155110 |
| Acute respiratory failure | 68.19 | 9.79 | 204 | 135055 | 31054 | 53182753 |
| Cardiac disorder | 67.76 | 9.79 | 267 | 134992 | 46699 | 53167108 |
| Treatment failure | 66.69 | 9.79 | 141 | 135118 | 128262 | 53085545 |
| Injection site pain | 66.32 | 9.79 | 116 | 135143 | 113275 | 53100532 |
| Nasopharyngitis | 66.18 | 9.79 | 257 | 135002 | 192038 | 53021769 |
| Right ventricular failure | 65.44 | 9.79 | 137 | 135122 | 16706 | 53197101 |
| Completed suicide | 62.78 | 9.79 | 163 | 135096 | 138038 | 53075769 |
| Abortion spontaneous | 62.73 | 9.79 | 20 | 135239 | 46615 | 53167192 |
| Asthenia | 62.16 | 9.79 | 1219 | 134040 | 342371 | 52871436 |
| Inadequate aseptic technique in use of product | 61.85 | 9.79 | 20 | 135239 | 114 | 53213693 |
| Muscle injury | 59.74 | 9.79 | 4 | 135255 | 29762 | 53184045 |
| Fatigue | 59.39 | 9.79 | 1406 | 133853 | 729100 | 52484707 |
| Psoriatic arthropathy | 59.16 | 9.79 | 24 | 135235 | 48166 | 53165641 |
| Electrolyte imbalance | 58.13 | 9.79 | 140 | 135119 | 18744 | 53195063 |
| Glaucoma | 57.74 | 9.79 | 131 | 135128 | 16872 | 53196935 |
| Mental status changes | 57.11 | 9.79 | 225 | 135034 | 39346 | 53174461 |
| Toxicity to various agents | 57.01 | 9.79 | 325 | 134934 | 219273 | 52994534 |
| Hepatic enzyme increased | 56.43 | 9.79 | 150 | 135109 | 126045 | 53087762 |
| Folliculitis | 56.33 | 9.79 | 7 | 135252 | 31702 | 53182105 |
| Suicidal ideation | 55.77 | 9.79 | 43 | 135216 | 60468 | 53153339 |
| Abdominal pain | 55.40 | 9.79 | 934 | 134325 | 254969 | 52958838 |
| Fluid imbalance | 53.64 | 9.79 | 25 | 135234 | 419 | 53213388 |
| Synovitis | 52.32 | 9.79 | 123 | 135136 | 107770 | 53106037 |
| Injection site reaction | 51.59 | 9.79 | 33 | 135226 | 51133 | 53162674 |
| Abdominal discomfort | 51.21 | 9.79 | 339 | 134920 | 220723 | 52993084 |
| Pleuroperitoneal communication | 49.94 | 9.79 | 15 | 135244 | 64 | 53213743 |
| Injection site erythema | 49.88 | 9.79 | 74 | 135185 | 77175 | 53136632 |
| Asthma | 49.88 | 9.79 | 128 | 135131 | 108844 | 53104963 |
| Swelling | 49.50 | 9.79 | 283 | 134976 | 190822 | 53022985 |
| Acute kidney injury | 48.00 | 9.79 | 907 | 134352 | 252961 | 52960846 |
| Irritable bowel syndrome | 47 | 9.79 | 26 | 135233 | 43606 | 53170201 |
| Diverticulitis | 46.46 | 9.79 | 197 | 135062 | 35604 | 53178203 |
| Device related infection | 46.24 | 9.79 | 145 | 135114 | 22641 | 53191166 |
| Oedema | 46.22 | 9.79 | 335 | 134924 | 74011 | 53139796 |
| Sinusitis | 46.18 | 9.79 | 245 | 135014 | 168319 | 53045488 |
| Loss of personal independence in daily activities | 45.94 | 9.79 | 66 | 135193 | 69749 | 53144058 |
| Non-cardiogenic pulmonary oedema | 45.70 | 9.79 | 25 | 135234 | 596 | 53213211 |
| Umbilical hernia | 45.18 | 9.79 | 45 | 135214 | 2757 | 53211050 |
| Cytokine release syndrome | 45.11 | 9.79 | 77 | 135182 | 8052 | 53205755 |
| Discomfort | 44.58 | 9.79 | 111 | 135148 | 95361 | 53118446 |
| Diabetes insipidus | 44.36 | 9.79 | 43 | 135216 | 2548 | 53211259 |
| Injection site bruising | 44.21 | 9.79 | 20 | 135239 | 37626 | 53176181 |
| Intentional self-injury | 43.90 | 9.79 | 6 | 135253 | 25278 | 53188529 |
| Septic shock | 43.76 | 9.79 | 289 | 134970 | 61940 | 53151867 |
| Anaemia | 43.52 | 9.79 | 962 | 134297 | 275756 | 52938051 |
| Renal ischaemia | 43.43 | 9.79 | 24 | 135235 | 584 | 53213223 |
| Noninfectious peritonitis | 43.01 | 9.79 | 18 | 135241 | 230 | 53213577 |
| Impaired healing | 42.94 | 9.79 | 60 | 135199 | 64145 | 53149662 |
| Sopor | 41.82 | 9.79 | 3 | 135256 | 21081 | 53192726 |
| Hernia | 41.67 | 9.79 | 85 | 135174 | 10175 | 53203632 |
| Injection site swelling | 40.95 | 9.79 | 29 | 135230 | 42599 | 53171208 |
| Diabetic complication | 40.25 | 9.79 | 27 | 135232 | 939 | 53212868 |
| Febrile neutropenia | 39.75 | 9.79 | 424 | 134835 | 104512 | 53109295 |
| Pregnancy | 39.67 | 9.79 | 15 | 135244 | 31426 | 53182381 |
| Hypophagia | 38.83 | 9.79 | 169 | 135090 | 30893 | 53182914 |
| Product use in unapproved indication | 38.64 | 9.79 | 150 | 135109 | 112139 | 53101668 |
| Blood urea increased | 38.54 | 9.79 | 150 | 135109 | 26081 | 53187726 |
| Dyspnoea | 38.28 | 9.79 | 1834 | 133425 | 584398 | 52629409 |
| Peritoneal effluent abnormal | 38.09 | 9.79 | 12 | 135247 | 62 | 53213745 |
| Arthritis | 38.08 | 9.79 | 105 | 135154 | 87193 | 53126614 |
| Ill-defined disorder | 37.46 | 9.79 | 42 | 135217 | 49402 | 53164405 |
| PO2 increased | 37.28 | 9.79 | 25 | 135234 | 869 | 53212938 |
| Hypernatraemia | 37.16 | 9.79 | 65 | 135194 | 6932 | 53206875 |
| Haemoglobin decreased | 36.49 | 9.79 | 519 | 134740 | 136788 | 53077019 |
| International normalised ratio increased | 35.53 | 9.79 | 225 | 135034 | 47536 | 53166271 |
| Renal failure | 35.28 | 9.79 | 457 | 134802 | 117995 | 53095812 |
| Gangrene | 35.06 | 9.79 | 52 | 135207 | 4825 | 53208982 |
| Pulmonary arterial hypertension | 35.00 | 9.79 | 149 | 135110 | 26973 | 53186834 |
| C-reactive protein abnormal | 34.96 | 9.79 | 11 | 135248 | 25859 | 53187948 |
| Treatment noncompliance | 34.84 | 9.79 | 171 | 135088 | 32864 | 53180943 |
| Injection site pruritus | 34.13 | 9.79 | 33 | 135226 | 41556 | 53172251 |
| Intentional product use issue | 34.06 | 9.79 | 84 | 135175 | 72410 | 53141397 |
| Azotaemia | 33.72 | 9.79 | 49 | 135210 | 4464 | 53209343 |
| Urticaria | 33.69 | 9.79 | 204 | 135055 | 135681 | 53078126 |
| Failure to thrive | 33.36 | 9.79 | 62 | 135197 | 6930 | 53206877 |
| Catheter site extravasation | 32.05 | 9.79 | 16 | 135243 | 314 | 53213493 |
| Blood pressure decreased | 31.92 | 9.79 | 267 | 134992 | 61602 | 53152205 |
| Blood bilirubin increased | 30.85 | 9.79 | 175 | 135084 | 35555 | 53178252 |
| Gastrooesophageal reflux disease | 30.83 | 9.79 | 333 | 134926 | 82330 | 53131477 |
| Heparin-induced thrombocytopenia | 30.57 | 9.79 | 47 | 135212 | 4502 | 53209305 |
| Blood magnesium decreased | 30.55 | 9.79 | 82 | 135177 | 11732 | 53202075 |
| PCO2 increased | 29.93 | 9.79 | 25 | 135234 | 1218 | 53212589 |
| Pneumoperitoneum | 29.72 | 9.79 | 28 | 135231 | 1601 | 53212206 |
| Condition aggravated | 29.53 | 9.79 | 553 | 134706 | 296581 | 52917226 |
| Hip arthroplasty | 29.44 | 9.79 | 17 | 135242 | 27845 | 53185962 |
| Sleep disorder | 29.43 | 9.79 | 66 | 135193 | 58804 | 53155003 |
| Decreased appetite | 29.35 | 9.79 | 733 | 134526 | 214241 | 52999566 |
| Inappropriate schedule of product administration | 29.11 | 9.79 | 95 | 135164 | 74783 | 53139024 |
| Cor pulmonale | 28.53 | 9.79 | 30 | 135229 | 1960 | 53211847 |
| Coma | 28.43 | 9.79 | 260 | 134999 | 61523 | 53152284 |
| Therapeutic response decreased | 28.40 | 9.79 | 48 | 135211 | 47521 | 53166286 |
| Cardiogenic shock | 28.19 | 9.79 | 103 | 135156 | 17379 | 53196428 |
| Brain natriuretic peptide increased | 27.79 | 9.79 | 47 | 135212 | 4878 | 53208929 |
| Device occlusion | 27.42 | 9.79 | 56 | 135203 | 6709 | 53207098 |
| Atrial flutter | 27.29 | 9.79 | 69 | 135190 | 9522 | 53204285 |
| Knee arthroplasty | 27.12 | 9.79 | 27 | 135232 | 33542 | 53180265 |
| Chronic obstructive pulmonary disease | 27.09 | 9.79 | 255 | 135004 | 60818 | 53152989 |
| Paraesthesia | 26.82 | 9.79 | 201 | 135058 | 127314 | 53086493 |
| Cardiac dysfunction | 26.78 | 9.79 | 28 | 135231 | 1817 | 53211990 |
| Blood albumin decreased | 26.31 | 9.79 | 89 | 135170 | 14453 | 53199354 |
| Multiple sclerosis relapse | 26.10 | 9.79 | 46 | 135213 | 44807 | 53169000 |
| Calcium deficiency | 26.03 | 9.79 | 21 | 135238 | 974 | 53212833 |
| Red blood cell sedimentation rate increased | 25.77 | 9.79 | 20 | 135239 | 28037 | 53185770 |
| Drug interaction | 25.73 | 9.79 | 396 | 134863 | 218933 | 52994874 |
| Vomiting | 25.69 | 9.79 | 1522 | 133737 | 495617 | 52718190 |
| Blood cholesterol increased | 25.20 | 9.79 | 61 | 135198 | 52928 | 53160879 |
| Deep vein thrombosis | 25.14 | 9.79 | 321 | 134938 | 82592 | 53131215 |
| Blood glucose decreased | 25.09 | 9.79 | 109 | 135150 | 19907 | 53193900 |
| Abdominal hernia | 25.08 | 9.79 | 45 | 135214 | 4895 | 53208912 |
| Inflammation | 24.71 | 9.79 | 69 | 135190 | 57067 | 53156740 |
| Acute left ventricular failure | 23.95 | 9.79 | 19 | 135240 | 860 | 53212947 |
| Thrombocytopenia | 23.93 | 9.79 | 489 | 134770 | 138238 | 53075569 |
| Exposure during pregnancy | 23.86 | 9.79 | 202 | 135057 | 124658 | 53089149 |
| Encephalopathy | 23.53 | 9.79 | 167 | 135092 | 36641 | 53177166 |
| Encapsulating peritoneal sclerosis | 23.41 | 9.79 | 14 | 135245 | 397 | 53213410 |
| Wrong product administered | 23.26 | 9.79 | 49 | 135210 | 5999 | 53207808 |
| Blood potassium increased | 23.01 | 9.79 | 98 | 135161 | 17743 | 53196064 |
| Bronchitis | 22.92 | 9.79 | 405 | 134854 | 111494 | 53102313 |
| Plasma cell myeloma | 22.81 | 9.79 | 203 | 135056 | 47671 | 53166136 |
| Drug reaction with eosinophilia and systemic symptoms | 22.58 | 9.79 | 30 | 135229 | 32770 | 53181037 |
| Migraine | 22.49 | 9.79 | 116 | 135143 | 80301 | 53133506 |
| Pruritus | 22.22 | 9.79 | 571 | 134688 | 293261 | 52920546 |
| Wrong technique in product usage process | 22.08 | 9.79 | 78 | 135181 | 59954 | 53153853 |
| Blood bicarbonate decreased | 21.90 | 9.79 | 32 | 135227 | 2930 | 53210877 |
| White blood cell count decreased | 21.87 | 9.79 | 440 | 134819 | 124035 | 53089772 |
| Hypovolaemia | 21.85 | 9.79 | 67 | 135192 | 10335 | 53203472 |
| Hyperglycaemia | 21.76 | 9.79 | 175 | 135084 | 39909 | 53173898 |
| Herpes zoster | 21.72 | 9.79 | 105 | 135154 | 73914 | 53139893 |
| Disability | 21.62 | 9.79 | 3 | 135256 | 12495 | 53201312 |
| Serotonin syndrome | 21.61 | 9.79 | 21 | 135238 | 26385 | 53187422 |
| Pulse absent | 21.60 | 9.79 | 44 | 135215 | 5262 | 53208545 |
| Tonsillar haemorrhage | 21.45 | 9.79 | 11 | 135248 | 229 | 53213578 |
| Bacteraemia | 21.30 | 9.79 | 87 | 135172 | 15462 | 53198345 |
| Multiple organ dysfunction syndrome | 21.08 | 9.79 | 225 | 135034 | 55452 | 53158355 |
| Extremity necrosis | 21.08 | 9.79 | 24 | 135235 | 1715 | 53212092 |
| Urine chloride decreased | 21.04 | 9.79 | 8 | 135251 | 78 | 53213729 |
| Haemorrhage | 20.88 | 9.79 | 232 | 135027 | 57755 | 53156052 |
| Cardiomegaly | 20.85 | 9.79 | 95 | 135164 | 17705 | 53196102 |
| Urinary tract infection | 20.64 | 9.79 | 773 | 134486 | 239130 | 52974677 |
| Peritoneal effluent leukocyte count increased | 20.28 | 9.79 | 6 | 135253 | 24 | 53213783 |
| Product selection error | 20.27 | 9.79 | 8 | 135251 | 87 | 53213720 |
| Respiratory distress | 20.20 | 9.79 | 151 | 135108 | 33676 | 53180131 |
| Muscle spasticity | 20.14 | 9.79 | 10 | 135249 | 17828 | 53195979 |
| Metabolic alkalosis | 20.02 | 9.79 | 31 | 135228 | 2988 | 53210819 |
| Posterior reversible encephalopathy syndrome | 19.91 | 9.79 | 8 | 135251 | 16152 | 53197655 |
| Transfusion | 19.88 | 9.79 | 78 | 135181 | 13609 | 53200198 |
| Vertigo | 19.88 | 9.79 | 74 | 135185 | 56007 | 53157800 |
| Insomnia | 19.87 | 9.79 | 344 | 134915 | 186728 | 53027079 |
| Small intestinal obstruction | 19.70 | 9.79 | 91 | 135168 | 17056 | 53196751 |
| Joint stiffness | 19.55 | 9.79 | 29 | 135230 | 30254 | 53183553 |
| Prothrombin time prolonged | 19.46 | 9.79 | 62 | 135197 | 9760 | 53204047 |
| Staphylococcus test positive | 19.31 | 9.79 | 35 | 135224 | 3838 | 53209969 |
| Electrocardiogram T wave peaked | 19.13 | 9.79 | 10 | 135249 | 217 | 53213590 |
| Bacterial translocation | 19.13 | 9.79 | 10 | 135249 | 217 | 53213590 |
| Hepatocellular injury | 19.08 | 9.79 | 29 | 135230 | 29957 | 53183850 |
| Gastrointestinal disorder | 18.86 | 9.79 | 142 | 135117 | 89862 | 53123945 |
| Blood pH decreased | 18.85 | 9.79 | 28 | 135231 | 2602 | 53211205 |
| Unresponsive to stimuli | 18.72 | 9.79 | 147 | 135112 | 33279 | 53180528 |
| Cognitive disorder | 18.68 | 9.79 | 55 | 135204 | 44723 | 53169084 |
| Foot deformity | 18.68 | 9.79 | 12 | 135247 | 18556 | 53195251 |
| Metabolic encephalopathy | 18.63 | 9.79 | 44 | 135215 | 5817 | 53207990 |
| Cardiac failure acute | 18.57 | 9.79 | 58 | 135201 | 9034 | 53204773 |
| Diarrhoea | 18.54 | 9.79 | 1833 | 133426 | 623713 | 52590094 |
| Hypomagnesaemia | 18.52 | 9.79 | 117 | 135142 | 24694 | 53189113 |
| Catheter management | 18.51 | 9.79 | 29 | 135230 | 2823 | 53210984 |
| Tendonitis | 18.51 | 9.79 | 10 | 135249 | 16996 | 53196811 |
| Osteonecrosis of jaw | 18.49 | 9.79 | 40 | 135219 | 36106 | 53177701 |
| Osteoarthritis | 18.43 | 9.79 | 104 | 135155 | 70382 | 53143425 |
| Hypoalbuminaemia | 18.11 | 9.79 | 65 | 135194 | 10871 | 53202936 |
| Overdose | 18.11 | 9.79 | 180 | 135079 | 107556 | 53106251 |
| Gait disturbance | 17.87 | 9.79 | 289 | 134970 | 158553 | 53055254 |
| Acne | 17.86 | 9.79 | 17 | 135242 | 21569 | 53192238 |
| Grip strength decreased | 17.76 | 9.79 | 4 | 135255 | 11745 | 53202062 |
| Oxygen consumption increased | 17.63 | 9.79 | 33 | 135226 | 3708 | 53210099 |
| Procedural complication | 17.52 | 9.79 | 40 | 135219 | 5172 | 53208635 |
| Injection site warmth | 17.40 | 9.79 | 7 | 135252 | 14121 | 53199686 |
| Peritoneal disorder | 17.35 | 9.79 | 13 | 135246 | 540 | 53213267 |
| Blood glucose increased | 17.29 | 9.79 | 284 | 134975 | 77077 | 53136730 |
| Generalised oedema | 17.25 | 9.79 | 80 | 135179 | 15019 | 53198788 |
| Full blood count decreased | 17.13 | 9.79 | 112 | 135147 | 23917 | 53189890 |
| Blister | 17.10 | 9.79 | 123 | 135136 | 78630 | 53135177 |
| Oxygen saturation abnormal | 17.07 | 9.79 | 28 | 135231 | 2834 | 53210973 |
| Abdominal pain upper | 16.95 | 9.79 | 308 | 134951 | 165983 | 53047824 |
| Hepatitis | 16.93 | 9.79 | 38 | 135221 | 33856 | 53179951 |
| Device related sepsis | 16.93 | 9.79 | 32 | 135227 | 3623 | 53210184 |
| Granulocytopenia | 16.87 | 9.79 | 41 | 135218 | 5519 | 53208288 |
| Mental status changes postoperative | 16.78 | 9.79 | 9 | 135250 | 206 | 53213601 |
| Device difficult to use | 16.76 | 9.79 | 3 | 135256 | 10356 | 53203451 |
| Mobility decreased | 16.62 | 9.79 | 119 | 135140 | 76152 | 53137655 |
| Blood calcium decreased | 16.46 | 9.79 | 96 | 135163 | 19698 | 53194109 |
| Injection site rash | 16.29 | 9.79 | 11 | 135248 | 16568 | 53197239 |
| Corneal oedema | 16.26 | 9.79 | 22 | 135237 | 1875 | 53211932 |
| Blood potassium abnormal | 16.20 | 9.79 | 25 | 135234 | 2402 | 53211405 |
| Pain in extremity | 16.09 | 9.79 | 576 | 134683 | 284474 | 52929333 |
| Hydrothorax | 15.84 | 9.79 | 14 | 135245 | 737 | 53213070 |
| Extravasation | 15.84 | 9.79 | 24 | 135235 | 2270 | 53211537 |
| Tenosynovitis | 15.82 | 9.79 | 3 | 135256 | 9936 | 53203871 |
| Oropharyngeal pain | 15.74 | 9.79 | 131 | 135128 | 81137 | 53132670 |
| Fibromyalgia | 15.72 | 9.79 | 58 | 135201 | 44017 | 53169790 |
| Intentional product misuse | 15.72 | 9.79 | 68 | 135191 | 49324 | 53164483 |
| Chest pain | 15.68 | 9.79 | 610 | 134649 | 189575 | 53024232 |
| Suicide attempt | 15.66 | 9.79 | 85 | 135174 | 58083 | 53155724 |
| Haematocrit decreased | 15.63 | 9.79 | 154 | 135105 | 37177 | 53176630 |
| Urine sodium decreased | 15.62 | 9.79 | 8 | 135251 | 166 | 53213641 |
| Arrhythmia | 15.53 | 9.79 | 152 | 135107 | 36627 | 53177180 |
| Decubitus ulcer | 15.41 | 9.79 | 60 | 135199 | 10433 | 53203374 |
| Product storage error | 15.38 | 9.79 | 7 | 135252 | 13123 | 53200684 |
| Ventricular tachycardia | 15.33 | 9.79 | 87 | 135172 | 17675 | 53196132 |
| Ascites | 15.24 | 9.79 | 161 | 135098 | 39574 | 53174233 |
| Marasmus | 15.19 | 9.79 | 12 | 135247 | 540 | 53213267 |
| Supraventricular tachycardia | 14.99 | 9.79 | 74 | 135185 | 14251 | 53199556 |
| Acinetobacter sepsis | 14.94 | 9.79 | 3 | 135256 | 0 | 53213807 |
| Vascular device infection | 14.94 | 9.79 | 34 | 135225 | 4387 | 53209420 |
| Clostridium difficile infection | 14.72 | 9.79 | 121 | 135138 | 27772 | 53186035 |
| Blood alkaline phosphatase increased | 14.67 | 9.79 | 165 | 135094 | 41197 | 53172610 |
| Critical illness | 14.65 | 9.79 | 8 | 135251 | 190 | 53213617 |
| Pancytopenia | 14.53 | 9.79 | 317 | 134942 | 90611 | 53123196 |
| Pharyngitis | 14.51 | 9.79 | 16 | 135243 | 18964 | 53194843 |
| Oxalosis | 14.47 | 9.79 | 5 | 135254 | 36 | 53213771 |
| Activated partial thromboplastin time prolonged | 14.39 | 9.79 | 45 | 135214 | 7014 | 53206793 |
| Impaired work ability | 14.32 | 9.79 | 9 | 135250 | 14081 | 53199726 |
| Atelectasis | 14.28 | 9.79 | 93 | 135166 | 19833 | 53193974 |
| Dry eye | 14.27 | 9.79 | 41 | 135218 | 33603 | 53180204 |
| Platelet count decreased | 14.26 | 9.79 | 367 | 134892 | 107732 | 53106075 |
| Accidental exposure to product | 14.03 | 9.79 | 24 | 135235 | 23650 | 53190157 |
| Depression | 14.01 | 9.79 | 355 | 134904 | 182697 | 53031110 |
| Interstitial lung disease | 14.00 | 9.79 | 89 | 135170 | 58533 | 53155274 |
| Colitis | 13.95 | 9.79 | 164 | 135095 | 41388 | 53172419 |
| Tachypnoea | 13.91 | 9.79 | 78 | 135181 | 15776 | 53198031 |
| Catheter site haemorrhage | 13.84 | 9.79 | 26 | 135233 | 2929 | 53210878 |
| Hyponatraemia | 13.83 | 9.79 | 367 | 134892 | 108240 | 53105567 |
| Skin dystrophy | 13.80 | 9.79 | 5 | 135254 | 42 | 53213765 |
| Hot flush | 13.77 | 9.79 | 67 | 135192 | 47093 | 53166714 |
| Stomatitis | 13.72 | 9.79 | 171 | 135088 | 97987 | 53115820 |
| Product substitution issue | 13.71 | 9.79 | 12 | 135247 | 15854 | 53197953 |
| Shock | 13.65 | 9.79 | 103 | 135156 | 23036 | 53190771 |
| Posthaemorrhagic hydrocephalus | 13.52 | 9.79 | 4 | 135255 | 16 | 53213791 |
| Escherichia peritonitis | 13.52 | 9.79 | 4 | 135255 | 16 | 53213791 |
| Ventricular fibrillation | 13.49 | 9.79 | 63 | 135196 | 11862 | 53201945 |
| Cholelithiasis | 13.45 | 9.79 | 161 | 135098 | 40803 | 53173004 |
| Abdominal incarcerated hernia | 13.33 | 9.79 | 4 | 135255 | 17 | 53213790 |
| Nutritional condition abnormal | 13.32 | 9.79 | 13 | 135246 | 777 | 53213030 |
| Catheter site abscess | 13.31 | 9.79 | 5 | 135254 | 47 | 53213760 |
| Nosocomial infection | 13.23 | 9.79 | 19 | 135240 | 1712 | 53212095 |
| Coeliac disease | 13.15 | 9.79 | 3 | 135256 | 8732 | 53205075 |
| Poisoning deliberate | 13.10 | 9.79 | 3 | 135256 | 8710 | 53205097 |
| Product compounding quality issue | 13.07 | 9.79 | 6 | 135253 | 97 | 53213710 |
| Drug resistance | 13 | 9.79 | 19 | 135240 | 19943 | 53193864 |
| Product residue present | 12.99 | 9.79 | 31 | 135228 | 4125 | 53209682 |
| Oral herpes | 12.99 | 9.79 | 21 | 135238 | 21158 | 53192649 |
| Postoperative adhesion | 12.98 | 9.79 | 8 | 135251 | 240 | 53213567 |
| Movement disorder | 12.95 | 9.79 | 17 | 135242 | 18664 | 53195143 |
| Blood chloride decreased | 12.92 | 9.79 | 37 | 135222 | 5494 | 53208313 |
| Confusion postoperative | 12.86 | 9.79 | 8 | 135251 | 244 | 53213563 |
| Blood creatinine increased | 12.83 | 9.79 | 287 | 134972 | 82375 | 53131432 |
| Aspartate aminotransferase increased | 12.81 | 9.79 | 291 | 134968 | 83738 | 53130069 |
| Akathisia | 12.79 | 9.79 | 3 | 135256 | 8568 | 53205239 |
| Post procedural complication | 12.69 | 9.79 | 79 | 135180 | 16587 | 53197220 |
| Foetal death | 12.57 | 9.79 | 52 | 135207 | 9295 | 53204512 |
| Poisoning | 12.56 | 9.79 | 10 | 135249 | 13840 | 53199967 |
| Psychomotor hyperactivity | 12.43 | 9.79 | 5 | 135254 | 10091 | 53203716 |
| Toxic epidermal necrolysis | 12.34 | 9.79 | 102 | 135157 | 23448 | 53190359 |
| Depressed mood | 12.31 | 9.79 | 50 | 135209 | 36914 | 53176893 |
| Alkalosis | 12.27 | 9.79 | 9 | 135250 | 362 | 53213445 |
| Sudden death | 12.23 | 9.79 | 55 | 135204 | 10193 | 53203614 |
| Cyst | 12.12 | 9.79 | 9 | 135250 | 12902 | 53200905 |
| Torsade de pointes | 12.09 | 9.79 | 65 | 135194 | 12940 | 53200867 |
| Ileus | 12.09 | 9.79 | 72 | 135187 | 14883 | 53198924 |
| Thrombosis | 12.07 | 9.79 | 219 | 135040 | 60574 | 53153233 |
| Obstructive airways disorder | 11.94 | 9.79 | 16 | 135243 | 17413 | 53196394 |
| Nodule | 11.94 | 9.79 | 16 | 135243 | 17413 | 53196394 |
| Chronic kidney disease | 11.93 | 9.79 | 165 | 135094 | 43205 | 53170602 |
| Calciphylaxis | 11.89 | 9.79 | 24 | 135235 | 2851 | 53210956 |
| Cellulitis | 11.85 | 9.79 | 264 | 134995 | 75725 | 53138082 |
| Hypoaesthesia | 11.83 | 9.79 | 252 | 135007 | 132743 | 53081064 |
| Hyperoxaluria | 11.78 | 9.79 | 6 | 135253 | 123 | 53213684 |
| Haemodynamic instability | 11.70 | 9.79 | 48 | 135211 | 8546 | 53205261 |
| Upper gastrointestinal haemorrhage | 11.68 | 9.79 | 80 | 135179 | 17350 | 53196457 |
| Thyroid disorder | 11.63 | 9.79 | 66 | 135193 | 13407 | 53200400 |
| Adverse event | 11.61 | 9.79 | 59 | 135200 | 41002 | 53172805 |
| Cardiovascular insufficiency | 11.59 | 9.79 | 16 | 135243 | 1390 | 53212417 |
| Urosepsis | 11.58 | 9.79 | 77 | 135182 | 16533 | 53197274 |
| Incision site pain | 11.52 | 9.79 | 14 | 135245 | 1072 | 53212735 |
| Pseudomonal bacteraemia | 11.51 | 9.79 | 16 | 135243 | 1399 | 53212408 |
| Blood pressure diastolic abnormal | 11.32 | 9.79 | 4 | 135255 | 8741 | 53205066 |
| Gastrointestinal stoma output decreased | 11.32 | 9.79 | 4 | 135255 | 31 | 53213776 |
| Incarcerated hernia | 11.32 | 9.79 | 6 | 135253 | 134 | 53213673 |
| Infantile apnoea | 11.30 | 9.79 | 13 | 135246 | 939 | 53212868 |
| Sedation | 11.29 | 9.79 | 38 | 135221 | 29637 | 53184170 |
| Schizophrenia | 11.25 | 9.79 | 6 | 135253 | 10273 | 53203534 |
| Coagulopathy | 11.24 | 9.79 | 87 | 135172 | 19611 | 53194196 |
| Tissue injury | 11.21 | 9.79 | 4 | 135255 | 32 | 53213775 |
| Pericardial effusion | 11.16 | 9.79 | 112 | 135147 | 27166 | 53186641 |
| Panniculitis | 11.15 | 9.79 | 3 | 135256 | 7811 | 53205996 |
| Cardiac procedure complication | 11.12 | 9.79 | 7 | 135252 | 218 | 53213589 |
| Type 2 diabetes mellitus | 11.08 | 9.79 | 42 | 135217 | 31628 | 53182179 |
| Hip fracture | 11.07 | 9.79 | 115 | 135144 | 28142 | 53185665 |
| Labelled drug-drug interaction medication error | 11.02 | 9.79 | 7 | 135252 | 10892 | 53202915 |
| Cytotoxic oedema | 11.01 | 9.79 | 6 | 135253 | 142 | 53213665 |
| Myalgia | 11 | 9.79 | 256 | 135003 | 133235 | 53080572 |
| Abortion induced | 10.89 | 9.79 | 7 | 135252 | 10819 | 53202988 |
| Leukocytosis | 10.83 | 9.79 | 103 | 135156 | 24631 | 53189176 |
| Device leakage | 10.81 | 9.79 | 37 | 135222 | 6043 | 53207764 |
| Gallbladder necrosis | 10.80 | 9.79 | 3 | 135256 | 9 | 53213798 |
| Sinoatrial block | 10.80 | 9.79 | 12 | 135247 | 835 | 53212972 |
| Urine output decreased | 10.75 | 9.79 | 58 | 135201 | 11565 | 53202242 |
| Disseminated intravascular coagulation | 10.65 | 9.79 | 86 | 135173 | 19633 | 53194174 |
| Central nervous system injury | 10.64 | 9.79 | 6 | 135253 | 152 | 53213655 |
| Ear pain | 10.61 | 9.79 | 39 | 135220 | 29634 | 53184173 |
| Corynebacterium test positive | 10.61 | 9.79 | 4 | 135255 | 38 | 53213769 |
| Serratia sepsis | 10.61 | 9.79 | 5 | 135254 | 86 | 53213721 |
| Stress | 10.61 | 9.79 | 93 | 135166 | 56991 | 53156816 |
| Night sweats | 10.58 | 9.79 | 49 | 135210 | 34898 | 53178909 |
| Product quality issue | 10.58 | 9.79 | 53 | 135206 | 36970 | 53176837 |
| Clostridium difficile colitis | 10.57 | 9.79 | 86 | 135173 | 19679 | 53194128 |
| Vascular access malfunction | 10.52 | 9.79 | 4 | 135255 | 39 | 53213768 |
| Product preparation error | 10.52 | 9.79 | 30 | 135229 | 4445 | 53209362 |
| Retinal ischaemia | 10.50 | 9.79 | 8 | 135251 | 341 | 53213466 |
| Acidosis hyperchloraemic | 10.44 | 9.79 | 8 | 135251 | 344 | 53213463 |
| Basal cell carcinoma | 10.40 | 9.79 | 28 | 135231 | 23441 | 53190366 |
| Staphylococcal infection | 10.34 | 9.79 | 146 | 135113 | 38402 | 53175405 |
| Oncologic complication | 10.33 | 9.79 | 6 | 135253 | 161 | 53213646 |
| Hyperdynamic left ventricle | 10.30 | 9.79 | 6 | 135253 | 162 | 53213645 |
| Hyperchloraemia | 10.21 | 9.79 | 11 | 135248 | 739 | 53213068 |
| Diabetic vascular disorder | 10.17 | 9.79 | 4 | 135255 | 43 | 53213764 |
| Pseudomonas peritonitis | 10.14 | 9.79 | 3 | 135256 | 12 | 53213795 |
| Influenza like illness | 10.09 | 9.79 | 102 | 135157 | 60757 | 53153050 |
| Blood aldosterone abnormal | 10.01 | 9.79 | 4 | 135255 | 45 | 53213762 |
| Extrapyramidal disorder | 9.99 | 9.79 | 10 | 135249 | 12392 | 53201415 |
| Chronic respiratory failure | 9.95 | 9.79 | 17 | 135242 | 1779 | 53212028 |
| Fibrin | 9.93 | 9.79 | 4 | 135255 | 46 | 53213761 |
| Overgrowth bacterial | 9.93 | 9.79 | 5 | 135254 | 100 | 53213707 |
| Joint range of motion decreased | 9.93 | 9.79 | 19 | 135240 | 17937 | 53195870 |
| Intestinal obstruction | 9.89 | 9.79 | 114 | 135145 | 28627 | 53185180 |
| Blood calcium abnormal | 9.85 | 9.79 | 13 | 135246 | 1082 | 53212725 |
| Immune effector cell-associated neurotoxicity syndrome | 9.80 | 9.79 | 13 | 135246 | 1087 | 53212720 |
| Neutrophil count decreased | 9.80 | 9.79 | 177 | 135082 | 48921 | 53164886 |
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Peritonitis bacterial | 2932.78 | 10.39 | 1186 | 98258 | 11310 | 32402772 |
| Peritonitis | 2098.00 | 10.39 | 1124 | 98320 | 21206 | 32392876 |
| Death | 1838.82 | 10.39 | 3764 | 95680 | 378753 | 32035329 |
| Peritoneal dialysis complication | 1235.60 | 10.39 | 472 | 98972 | 3796 | 32410286 |
| Fluid overload | 1089.05 | 10.39 | 703 | 98741 | 18918 | 32395164 |
| Abdominal distension | 356.01 | 10.39 | 595 | 98849 | 50700 | 32363382 |
| Ultrafiltration failure | 308.54 | 10.39 | 108 | 99336 | 655 | 32413427 |
| Fungal peritonitis | 304.75 | 10.39 | 127 | 99317 | 1309 | 32412773 |
| Drug ineffective | 264.67 | 10.39 | 482 | 98962 | 382995 | 32031087 |
| Bloody peritoneal effluent | 246.87 | 10.39 | 85 | 99359 | 487 | 32413595 |
| Sepsis | 245.15 | 10.39 | 1048 | 98396 | 157786 | 32256296 |
| Catheter site infection | 199.33 | 10.39 | 117 | 99327 | 2637 | 32411445 |
| Procedural pain | 196.84 | 10.39 | 150 | 99294 | 5279 | 32408803 |
| Drug abuse | 175.54 | 10.39 | 20 | 99424 | 80223 | 32333859 |
| Cardiac failure congestive | 168.04 | 10.39 | 606 | 98838 | 84246 | 32329836 |
| Hypotension | 167.97 | 10.39 | 1183 | 98261 | 214927 | 32199155 |
| Hypokalaemia | 154.09 | 10.39 | 443 | 99001 | 54651 | 32359431 |
| Cardiac arrest | 149.34 | 10.39 | 639 | 98805 | 96137 | 32317945 |
| Peritoneal cloudy effluent | 141.77 | 10.39 | 53 | 99391 | 398 | 32413684 |
| Cardiac disorder | 137.35 | 10.39 | 357 | 99087 | 41509 | 32372573 |
| Off label use | 136.94 | 10.39 | 480 | 98964 | 305840 | 32108242 |
| Diabetic foot | 129.04 | 10.39 | 91 | 99353 | 2835 | 32411247 |
| Fluid retention | 128.62 | 10.39 | 264 | 99180 | 26286 | 32387796 |
| Cardiac failure | 118.79 | 10.39 | 575 | 98869 | 91098 | 32322984 |
| Dehydration | 113.16 | 10.39 | 728 | 98716 | 128230 | 32285852 |
| Multimorbidity | 109.19 | 10.39 | 47 | 99397 | 528 | 32413554 |
| Drug interaction | 106.23 | 10.39 | 329 | 99115 | 217856 | 32196226 |
| Inadequate aseptic technique in use of product | 102.28 | 10.39 | 33 | 99411 | 149 | 32413933 |
| Hypervolaemia | 99.70 | 10.39 | 74 | 99370 | 2500 | 32411582 |
| Device related infection | 97.30 | 10.39 | 187 | 99257 | 17746 | 32396336 |
| Hernia | 93.73 | 10.39 | 130 | 99314 | 9385 | 32404697 |
| Rheumatoid arthritis | 92.77 | 10.39 | 13 | 99431 | 44531 | 32369551 |
| Toxicity to various agents | 91.27 | 10.39 | 262 | 99182 | 177779 | 32236303 |
| Disease complication | 91.13 | 10.39 | 73 | 99371 | 2766 | 32411316 |
| Cardiovascular disorder | 87.09 | 10.39 | 134 | 99310 | 10628 | 32403454 |
| Cardio-respiratory arrest | 85.72 | 10.39 | 369 | 99075 | 55620 | 32358462 |
| Inguinal hernia | 84.93 | 10.39 | 113 | 99331 | 7839 | 32406243 |
| Fluid imbalance | 83.35 | 10.39 | 36 | 99408 | 408 | 32413674 |
| Appendicolith | 76.22 | 10.39 | 69 | 99375 | 3096 | 32410986 |
| Headache | 76.16 | 10.39 | 325 | 99119 | 195872 | 32218210 |
| Acute myocardial infarction | 73.60 | 10.39 | 349 | 99095 | 54800 | 32359282 |
| Suicide attempt | 69.19 | 10.39 | 16 | 99428 | 38228 | 32375854 |
| Diabetic complication | 65.88 | 10.39 | 39 | 99405 | 893 | 32413189 |
| Noninfectious peritonitis | 63.24 | 10.39 | 25 | 99419 | 222 | 32413860 |
| Azotaemia | 63.06 | 10.39 | 80 | 99364 | 5294 | 32408788 |
| Arthralgia | 62.55 | 10.39 | 238 | 99206 | 148210 | 32265872 |
| Myocardial infarction | 62.52 | 10.39 | 623 | 98821 | 125053 | 32289029 |
| Psoriasis | 61.66 | 10.39 | 32 | 99412 | 46091 | 32367991 |
| Treatment failure | 60.55 | 10.39 | 22 | 99422 | 39141 | 32374941 |
| Therapeutic product effect incomplete | 59.37 | 10.39 | 26 | 99418 | 41315 | 32372767 |
| Peritoneal disorder | 59.26 | 10.39 | 28 | 99416 | 397 | 32413685 |
| Pneumonia | 59.19 | 10.39 | 1462 | 97982 | 353790 | 32060292 |
| Myelosuppression | 58.78 | 10.39 | 118 | 99326 | 11558 | 32402524 |
| Cardiogenic shock | 58.53 | 10.39 | 167 | 99277 | 20495 | 32393587 |
| Heparin-induced thrombocytopenia | 56.17 | 10.39 | 78 | 99366 | 5636 | 32408446 |
| Blood potassium decreased | 55.95 | 10.39 | 147 | 99297 | 17191 | 32396891 |
| Umbilical hernia | 55.63 | 10.39 | 67 | 99377 | 4203 | 32409879 |
| Peritoneal effluent abnormal | 54.94 | 10.39 | 20 | 99424 | 138 | 32413944 |
| Pulmonary oedema | 54.75 | 10.39 | 283 | 99161 | 45984 | 32368098 |
| Overdose | 52.38 | 10.39 | 118 | 99326 | 86959 | 32327123 |
| Device occlusion | 50.79 | 10.39 | 82 | 99362 | 6776 | 32407306 |
| Injection site pain | 50.38 | 10.39 | 19 | 99425 | 33039 | 32381043 |
| Abdominal pain | 50.15 | 10.39 | 687 | 98757 | 148842 | 32265240 |
| Product use in unapproved indication | 44.84 | 10.39 | 128 | 99316 | 87076 | 32327006 |
| Appendicitis | 44.60 | 10.39 | 90 | 99354 | 8847 | 32405235 |
| Hyperkalaemia | 42.87 | 10.39 | 362 | 99082 | 69388 | 32344694 |
| Drug reaction with eosinophilia and systemic symptoms | 42.73 | 10.39 | 23 | 99421 | 32462 | 32381620 |
| Administration site extravasation | 42.26 | 10.39 | 24 | 99420 | 507 | 32413575 |
| Incision site pain | 40.61 | 10.39 | 40 | 99404 | 1997 | 32412085 |
| Myalgia | 40.48 | 10.39 | 121 | 99323 | 81109 | 32332973 |
| Multiple organ dysfunction syndrome | 39.01 | 10.39 | 355 | 99089 | 69499 | 32344583 |
| Intentional product misuse | 38.71 | 10.39 | 32 | 99412 | 36019 | 32378063 |
| Gangrene | 38.39 | 10.39 | 60 | 99384 | 4822 | 32409260 |
| Hydrothorax | 36.43 | 10.39 | 22 | 99422 | 523 | 32413559 |
| Treatment noncompliance | 34.00 | 10.39 | 169 | 99275 | 27033 | 32387049 |
| Suicidal ideation | 33.76 | 10.39 | 40 | 99404 | 38043 | 32376039 |
| Drug resistance | 33.68 | 10.39 | 14 | 99430 | 22951 | 32391131 |
| Fatigue | 33.00 | 10.39 | 819 | 98625 | 349882 | 32064200 |
| Cardiac procedure complication | 32.88 | 10.39 | 16 | 99428 | 243 | 32413839 |
| Drug intolerance | 32.77 | 10.39 | 65 | 99379 | 50170 | 32363912 |
| Serotonin syndrome | 32.64 | 10.39 | 9 | 99435 | 19108 | 32394974 |
| Mental status changes | 32.05 | 10.39 | 214 | 99230 | 38123 | 32375959 |
| Asthma | 31.42 | 10.39 | 54 | 99390 | 44011 | 32370071 |
| Localised infection | 31.30 | 10.39 | 110 | 99334 | 15077 | 32399005 |
| Angioedema | 31.23 | 10.39 | 39 | 99405 | 36250 | 32377832 |
| Malnutrition | 31.20 | 10.39 | 96 | 99348 | 12282 | 32401800 |
| Aggression | 31.19 | 10.39 | 45 | 99399 | 39344 | 32374738 |
| Depression | 31.07 | 10.39 | 172 | 99272 | 96888 | 32317194 |
| Somnolence | 31.05 | 10.39 | 188 | 99256 | 103609 | 32310473 |
| Failure to thrive | 30.85 | 10.39 | 75 | 99369 | 8360 | 32405722 |
| Oedema | 30.80 | 10.39 | 240 | 99204 | 44907 | 32369175 |
| Intentional product use issue | 30.77 | 10.39 | 51 | 99393 | 42160 | 32371922 |
| Insomnia | 30.42 | 10.39 | 181 | 99263 | 100167 | 32313915 |
| Joint swelling | 29.58 | 10.39 | 72 | 99372 | 51663 | 32362419 |
| Spinal muscular atrophy | 29.36 | 10.39 | 16 | 99428 | 311 | 32413771 |
| Intentional overdose | 28.74 | 10.39 | 52 | 99392 | 41549 | 32372533 |
| Musculoskeletal stiffness | 28.10 | 10.39 | 48 | 99396 | 39216 | 32374866 |
| Staphylococcus test positive | 27.87 | 10.39 | 41 | 99403 | 3124 | 32410958 |
| Gastrointestinal haemorrhage | 27.79 | 10.39 | 396 | 99048 | 86486 | 32327596 |
| Abdominal hernia | 27.70 | 10.39 | 39 | 99405 | 2854 | 32411228 |
| Rash | 27.66 | 10.39 | 462 | 98982 | 208871 | 32205211 |
| Drug dependence | 27.57 | 10.39 | 19 | 99425 | 23465 | 32390617 |
| Cytokine release syndrome | 27.01 | 10.39 | 97 | 99347 | 13438 | 32400644 |
| Mycobacterial peritonitis | 26.99 | 10.39 | 9 | 99435 | 46 | 32414036 |
| Interstitial lung disease | 26.82 | 10.39 | 105 | 99339 | 64896 | 32349186 |
| Product use issue | 26.73 | 10.39 | 78 | 99366 | 52699 | 32361383 |
| Complication associated with device | 26.63 | 10.39 | 58 | 99386 | 6014 | 32408068 |
| Loss of personal independence in daily activities | 26.20 | 10.39 | 26 | 99418 | 26807 | 32387275 |
| Blood glucose decreased | 26.17 | 10.39 | 96 | 99348 | 13438 | 32400644 |
| Diaphragmatic spasm | 25.99 | 10.39 | 10 | 99434 | 82 | 32414000 |
| Blood urea increased | 25.69 | 10.39 | 178 | 99266 | 32095 | 32381987 |
| Lower respiratory tract infection | 25.61 | 10.39 | 31 | 99413 | 29212 | 32384870 |
| Respiratory failure | 25.12 | 10.39 | 464 | 98980 | 106718 | 32307364 |
| Cerebrovascular accident | 25.09 | 10.39 | 387 | 99057 | 85933 | 32328149 |
| Faecal volume decreased | 24.61 | 10.39 | 10 | 99434 | 96 | 32413986 |
| Eosinophilia | 24.58 | 10.39 | 24 | 99420 | 24934 | 32389148 |
| Sedation | 24.53 | 10.39 | 13 | 99431 | 18513 | 32395569 |
| Anxiety | 23.69 | 10.39 | 184 | 99260 | 95821 | 32318261 |
| Tachypnoea | 23.68 | 10.39 | 108 | 99336 | 16675 | 32397407 |
| Asthenia | 23.33 | 10.39 | 912 | 98532 | 235032 | 32179050 |
| Constipation | 23.31 | 10.39 | 528 | 98916 | 125845 | 32288237 |
| Disturbance in attention | 23.21 | 10.39 | 23 | 99421 | 23730 | 32390352 |
| Osteonecrosis of jaw | 23.18 | 10.39 | 15 | 99429 | 19151 | 32394931 |
| Sopor | 23.16 | 10.39 | 4 | 99440 | 11745 | 32402337 |
| Therapeutic product effect decreased | 23.05 | 10.39 | 37 | 99407 | 30980 | 32383102 |
| Contraindicated product administered | 22.98 | 10.39 | 15 | 99429 | 19061 | 32395021 |
| Psoriatic arthropathy | 22.97 | 10.39 | 13 | 99431 | 17847 | 32396235 |
| Hypoglycaemia | 22.97 | 10.39 | 261 | 99183 | 54121 | 32359961 |
| Intentional self-injury | 22.89 | 10.39 | 7 | 99437 | 13893 | 32400189 |
| Right ventricular failure | 22.61 | 10.39 | 67 | 99377 | 8396 | 32405686 |
| Inappropriate schedule of product administration | 22.29 | 10.39 | 69 | 99375 | 45756 | 32368326 |
| Therapeutic response decreased | 22.15 | 10.39 | 28 | 99416 | 25892 | 32388190 |
| Completed suicide | 22.05 | 10.39 | 179 | 99265 | 92338 | 32321744 |
| Product substitution issue | 21.83 | 10.39 | 3 | 99441 | 10433 | 32403649 |
| Gait disturbance | 21.32 | 10.39 | 151 | 99293 | 80257 | 32333825 |
| Calciphylaxis | 21.13 | 10.39 | 22 | 99422 | 1174 | 32412908 |
| Hip fracture | 21.11 | 10.39 | 82 | 99362 | 11793 | 32402289 |
| Extremity necrosis | 20.85 | 10.39 | 27 | 99417 | 1823 | 32412259 |
| Blood potassium increased | 20.71 | 10.39 | 104 | 99340 | 16700 | 32397382 |
| Sputum increased | 20.46 | 10.39 | 29 | 99415 | 2136 | 32411946 |
| Ascites | 20.30 | 10.39 | 200 | 99244 | 39991 | 32374091 |
| Cytomegalovirus infection | 20.25 | 10.39 | 29 | 99415 | 25435 | 32388647 |
| Swelling | 20.19 | 10.39 | 192 | 99252 | 38030 | 32376052 |
| Ureteric compression | 20.15 | 10.39 | 12 | 99432 | 278 | 32413804 |
| Withdrawal of life support | 20.02 | 10.39 | 6 | 99438 | 20 | 32414062 |
| Pleuroperitoneal communication | 19.92 | 10.39 | 7 | 99437 | 43 | 32414039 |
| Wrong product administered | 19.83 | 10.39 | 46 | 99398 | 4974 | 32409108 |
| Dyskinesia | 19.65 | 10.39 | 26 | 99418 | 23577 | 32390505 |
| Hospitalisation | 19.63 | 10.39 | 80 | 99364 | 48891 | 32365191 |
| Respiratory tract infection bacterial | 19.51 | 10.39 | 16 | 99428 | 627 | 32413455 |
| Cognitive disorder | 19.13 | 10.39 | 31 | 99413 | 25863 | 32388219 |
| Hypernatraemia | 19.05 | 10.39 | 62 | 99382 | 8171 | 32405911 |
| Foetal exposure during pregnancy | 18.82 | 10.39 | 64 | 99380 | 41237 | 32372845 |
| Hepatotoxicity | 18.58 | 10.39 | 19 | 99425 | 19318 | 32394764 |
| Psychotic disorder | 18.52 | 10.39 | 26 | 99418 | 22994 | 32391088 |
| Peripheral vascular disorder | 18.35 | 10.39 | 46 | 99398 | 5226 | 32408856 |
| Diabetic ulcer | 18.30 | 10.39 | 9 | 99435 | 140 | 32413942 |
| Product prescribing error | 18.24 | 10.39 | 20 | 99424 | 19697 | 32394385 |
| Urticaria | 17.80 | 10.39 | 108 | 99336 | 59506 | 32354576 |
| Epilepsy | 17.75 | 10.39 | 25 | 99419 | 22084 | 32391998 |
| Oropharyngeal pain | 17.63 | 10.39 | 44 | 99400 | 31308 | 32382774 |
| Osteonecrosis | 17.54 | 10.39 | 15 | 99429 | 16607 | 32397475 |
| Marasmus | 17.53 | 10.39 | 15 | 99429 | 624 | 32413458 |
| Hallucination | 17.51 | 10.39 | 92 | 99352 | 52527 | 32361555 |
| Neutropenia | 17.40 | 10.39 | 318 | 99126 | 141857 | 32272225 |
| Tremor | 17.26 | 10.39 | 162 | 99282 | 81115 | 32332967 |
| International normalised ratio increased | 17.09 | 10.39 | 227 | 99217 | 48808 | 32365274 |
| Red blood cells urine positive | 16.99 | 10.39 | 24 | 99420 | 1762 | 32412320 |
| Catheter site extravasation | 16.96 | 10.39 | 8 | 99436 | 113 | 32413969 |
| Cardiomyopathy | 16.93 | 10.39 | 95 | 99349 | 15918 | 32398164 |
| Sinusitis | 16.43 | 10.39 | 57 | 99387 | 36503 | 32377579 |
| Diabetic vascular disorder | 16.23 | 10.39 | 7 | 99437 | 79 | 32414003 |
| Cardiovascular insufficiency | 16.11 | 10.39 | 22 | 99422 | 1564 | 32412518 |
| Rhabdomyolysis | 16.09 | 10.39 | 130 | 99314 | 67135 | 32346947 |
| Metabolic alkalosis | 16.05 | 10.39 | 21 | 99423 | 1433 | 32412649 |
| Extravasation | 15.82 | 10.39 | 24 | 99420 | 1879 | 32412203 |
| Pruritus | 15.70 | 10.39 | 288 | 99156 | 128414 | 32285668 |
| Dizziness | 15.69 | 10.39 | 505 | 98939 | 209113 | 32204969 |
| Mood swings | 15.62 | 10.39 | 3 | 99441 | 8162 | 32405920 |
| Oedema peripheral | 15.56 | 10.39 | 458 | 98986 | 113633 | 32300449 |
| Atrial fibrillation | 15.51 | 10.39 | 467 | 98977 | 116237 | 32297845 |
| Hepatocellular carcinoma | 15.48 | 10.39 | 6 | 99438 | 10264 | 32403818 |
| Immune reconstitution inflammatory syndrome | 15.41 | 10.39 | 5 | 99439 | 9554 | 32404528 |
| Depressed mood | 15.40 | 10.39 | 20 | 99424 | 18280 | 32395802 |
| Withdrawal syndrome | 15.34 | 10.39 | 9 | 99435 | 12113 | 32401969 |
| Vertigo | 15.34 | 10.39 | 32 | 99412 | 24251 | 32389831 |
| Prescribed overdose | 15.31 | 10.39 | 5 | 99439 | 9514 | 32404568 |
| Feeling abnormal | 15.28 | 10.39 | 115 | 99329 | 60308 | 32353774 |
| Therapeutic product effect prolonged | 15.27 | 10.39 | 10 | 99434 | 275 | 32413807 |
| Rash maculo-papular | 15.24 | 10.39 | 40 | 99404 | 27982 | 32386100 |
| Bacterial translocation | 15.21 | 10.39 | 10 | 99434 | 277 | 32413805 |
| Pneumococcal sepsis | 15.02 | 10.39 | 16 | 99428 | 877 | 32413205 |
| Paraesthesia | 14.99 | 10.39 | 112 | 99332 | 58832 | 32355250 |
| Generalised tonic-clonic seizure | 14.98 | 10.39 | 25 | 99419 | 20614 | 32393468 |
| Scrotal swelling | 14.93 | 10.39 | 20 | 99424 | 1396 | 32412686 |
| Visual acuity reduced | 14.86 | 10.39 | 17 | 99427 | 16428 | 32397654 |
| Mental impairment | 14.85 | 10.39 | 6 | 99438 | 10006 | 32404076 |
| Schizophrenia | 14.78 | 10.39 | 6 | 99438 | 9978 | 32404104 |
| Dystonia | 14.75 | 10.39 | 7 | 99437 | 10616 | 32403466 |
| Arthropathy | 14.75 | 10.39 | 29 | 99415 | 22460 | 32391622 |
| Injection site bruising | 14.69 | 10.39 | 3 | 99441 | 7817 | 32406265 |
| Pseudomonas test positive | 14.65 | 10.39 | 17 | 99427 | 1025 | 32413057 |
| Bacteraemia | 14.47 | 10.39 | 98 | 99346 | 17535 | 32396547 |
| Blood albumin decreased | 14.47 | 10.39 | 78 | 99366 | 12875 | 32401207 |
| Product contamination microbial | 14.21 | 10.39 | 14 | 99430 | 699 | 32413383 |
| Osteoarthritis | 14.20 | 10.39 | 24 | 99420 | 19695 | 32394387 |
| Dyspnoea | 14.16 | 10.39 | 1288 | 98156 | 360757 | 32053325 |
| Squamous cell carcinoma | 14.08 | 10.39 | 8 | 99436 | 10960 | 32403122 |
| Sensory integrative dysfunction | 14.06 | 10.39 | 5 | 99439 | 32 | 32414050 |
| Pain | 14.00 | 10.39 | 452 | 98992 | 187104 | 32226978 |
| Emotional disorder of childhood | 13.93 | 10.39 | 5 | 99439 | 33 | 32414049 |
| Mania | 13.92 | 10.39 | 6 | 99438 | 9626 | 32404456 |
| Polyneuropathy | 13.85 | 10.39 | 12 | 99432 | 13203 | 32400879 |
| Stress | 13.84 | 10.39 | 122 | 99322 | 23660 | 32390422 |
| Arthritis | 13.84 | 10.39 | 39 | 99405 | 26653 | 32387429 |
| Pathogen resistance | 13.62 | 10.39 | 6 | 99438 | 9504 | 32404578 |
| Product container issue | 13.60 | 10.39 | 15 | 99429 | 855 | 32413227 |
| Pneumocystis jirovecii pneumonia | 13.56 | 10.39 | 23 | 99421 | 18847 | 32395235 |
| Leukopenia | 13.56 | 10.39 | 118 | 99326 | 60004 | 32354078 |
| Intercepted medication error | 13.51 | 10.39 | 12 | 99432 | 525 | 32413557 |
| Shoshin beriberi | 13.44 | 10.39 | 6 | 99438 | 74 | 32414008 |
| Urinary tract infection | 13.36 | 10.39 | 330 | 99114 | 79741 | 32334341 |
| Memory impairment | 13.34 | 10.39 | 71 | 99373 | 40408 | 32373674 |
| Tendonitis | 13.34 | 10.39 | 5 | 99439 | 8730 | 32405352 |
| Nosocomial infection | 13.32 | 10.39 | 18 | 99426 | 1267 | 32412815 |
| Face oedema | 13.20 | 10.39 | 10 | 99434 | 11765 | 32402317 |
| General physical health deterioration | 13.18 | 10.39 | 453 | 98991 | 114806 | 32299276 |
| Blood glucose increased | 13.10 | 10.39 | 276 | 99168 | 64965 | 32349117 |
| Abdominal discomfort | 13.08 | 10.39 | 230 | 99214 | 52394 | 32361688 |
| Lymphadenopathy | 13.01 | 10.39 | 41 | 99403 | 27041 | 32387041 |
| Postoperative wound infection | 13.00 | 10.39 | 38 | 99406 | 4726 | 32409356 |
| Product storage error | 12.99 | 10.39 | 3 | 99441 | 7175 | 32406907 |
| Blood pressure decreased | 12.96 | 10.39 | 224 | 99220 | 50856 | 32363226 |
| Increased bronchial secretion | 12.96 | 10.39 | 21 | 99423 | 1740 | 32412342 |
| Peritoneal perforation | 12.89 | 10.39 | 5 | 99439 | 42 | 32414040 |
| Body temperature decreased | 12.81 | 10.39 | 9 | 99435 | 11005 | 32403077 |
| Red blood cell sedimentation rate increased | 12.81 | 10.39 | 4 | 99440 | 7831 | 32406251 |
| Irritability | 12.80 | 10.39 | 36 | 99408 | 24618 | 32389464 |
| Infusion site necrosis | 12.78 | 10.39 | 4 | 99440 | 16 | 32414066 |
| Glycosylated haemoglobin increased | 12.74 | 10.39 | 8 | 99436 | 10381 | 32403701 |
| Erectile dysfunction | 12.65 | 10.39 | 26 | 99418 | 19813 | 32394269 |
| Vocal cord paralysis | 12.58 | 10.39 | 15 | 99429 | 931 | 32413151 |
| Bone marrow failure | 12.42 | 10.39 | 145 | 99299 | 30259 | 32383823 |
| Obstructive airways disorder | 12.37 | 10.39 | 11 | 99433 | 11950 | 32402132 |
| Hyperinsulinaemia | 12.34 | 10.39 | 6 | 99438 | 91 | 32413991 |
| Gastric ischaemia | 12.31 | 10.39 | 3 | 99441 | 3 | 32414079 |
| Mesenteric artery stenosis | 12.23 | 10.39 | 4 | 99440 | 19 | 32414063 |
| Posthaemorrhagic hydrocephalus | 12.22 | 10.39 | 6 | 99438 | 93 | 32413989 |
| Limb discomfort | 12.21 | 10.39 | 8 | 99436 | 10146 | 32403936 |
| Post procedural complication | 12.16 | 10.39 | 70 | 99374 | 11837 | 32402245 |
| Drug hypersensitivity | 12.10 | 10.39 | 155 | 99289 | 73245 | 32340837 |
| Erythema | 12.09 | 10.39 | 180 | 99264 | 82925 | 32331157 |
| Swelling of eyelid | 12.03 | 10.39 | 11 | 99433 | 500 | 32413582 |
| Gamma-glutamyltransferase increased | 11.89 | 10.39 | 51 | 99393 | 30731 | 32383351 |
| Lung consolidation | 11.89 | 10.39 | 40 | 99404 | 5363 | 32408719 |
| Product preparation error | 11.87 | 10.39 | 21 | 99423 | 1869 | 32412213 |
| Pleural effusion | 11.85 | 10.39 | 321 | 99123 | 78671 | 32335411 |
| Device related sepsis | 11.83 | 10.39 | 25 | 99419 | 2538 | 32411544 |
| Application site laceration | 11.75 | 10.39 | 4 | 99440 | 22 | 32414060 |
| Drug withdrawal syndrome | 11.68 | 10.39 | 28 | 99416 | 20203 | 32393879 |
| Toxic epidermal necrolysis | 11.66 | 10.39 | 105 | 99339 | 20488 | 32393594 |
| Herpes zoster | 11.64 | 10.39 | 55 | 99389 | 32286 | 32381796 |
| Hepatic enzyme increased | 11.64 | 10.39 | 66 | 99378 | 36971 | 32377111 |
| Angina pectoris | 11.58 | 10.39 | 53 | 99391 | 31373 | 32382709 |
| Panic attack | 11.54 | 10.39 | 7 | 99437 | 9254 | 32404828 |
| Blood pressure increased | 11.50 | 10.39 | 172 | 99272 | 79182 | 32334900 |
| Prostate cancer | 11.47 | 10.39 | 44 | 99400 | 27362 | 32386720 |
| Haemoglobin decreased | 11.42 | 10.39 | 461 | 98983 | 119210 | 32294872 |
| Septic shock | 11.41 | 10.39 | 284 | 99160 | 68705 | 32345377 |
| Ileus | 11.38 | 10.39 | 87 | 99357 | 16178 | 32397904 |
| Injection site erythema | 11.37 | 10.39 | 17 | 99427 | 14651 | 32399431 |
| Delusion | 11.37 | 10.39 | 14 | 99430 | 13094 | 32400988 |
| Pulmonary hypertension | 11.35 | 10.39 | 104 | 99340 | 20390 | 32393692 |
| Acute respiratory failure | 11.29 | 10.39 | 136 | 99308 | 28592 | 32385490 |
| Hyperinsulinaemic hypoglycaemia | 11.25 | 10.39 | 5 | 99439 | 61 | 32414021 |
| Cellulitis | 11.25 | 10.39 | 216 | 99228 | 50014 | 32364068 |
| Basal cell carcinoma | 11.22 | 10.39 | 23 | 99421 | 17545 | 32396537 |
| Nasopharyngitis | 11.16 | 10.39 | 133 | 99311 | 63654 | 32350428 |
| Hepatitis C | 11.14 | 10.39 | 15 | 99429 | 13503 | 32400579 |
| Lymphocyte count decreased | 11.11 | 10.39 | 106 | 99338 | 21013 | 32393069 |
| Anger | 11.09 | 10.39 | 12 | 99432 | 11892 | 32402190 |
| Paranoia | 11.08 | 10.39 | 10 | 99434 | 10789 | 32403293 |
| Dysarthria | 11.07 | 10.39 | 58 | 99386 | 33143 | 32380939 |
| Photosensitivity reaction | 10.93 | 10.39 | 9 | 99435 | 10154 | 32403928 |
| Injection site swelling | 10.93 | 10.39 | 8 | 99436 | 9576 | 32404506 |
| Mucosal inflammation | 10.82 | 10.39 | 59 | 99385 | 33375 | 32380707 |
| Blood creatine phosphokinase increased | 10.82 | 10.39 | 88 | 99356 | 45388 | 32368694 |
| Renal tubular acidosis | 10.79 | 10.39 | 21 | 99423 | 2011 | 32412071 |
| Atrial septal defect | 10.76 | 10.39 | 4 | 99440 | 7021 | 32407061 |
| Mood altered | 10.73 | 10.39 | 7 | 99437 | 8897 | 32405185 |
| Atelectasis | 10.72 | 10.39 | 88 | 99356 | 16720 | 32397362 |
| Pneumoperitoneum | 10.71 | 10.39 | 20 | 99424 | 1856 | 32412226 |
| Product contamination | 10.67 | 10.39 | 12 | 99432 | 699 | 32413383 |
| Sexual dysfunction | 10.66 | 10.39 | 3 | 99441 | 6286 | 32407796 |
| Incorrect drug administration rate | 10.66 | 10.39 | 16 | 99428 | 1241 | 32412841 |
| Hydrocele | 10.63 | 10.39 | 22 | 99422 | 2202 | 32411880 |
| Ventricular tachycardia | 10.49 | 10.39 | 122 | 99322 | 25434 | 32388648 |
| Suprapubic pain | 10.44 | 10.39 | 9 | 99435 | 378 | 32413704 |
| Injection site reaction | 10.41 | 10.39 | 12 | 99432 | 11557 | 32402525 |
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | B05CX01 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS IRRIGATING SOLUTIONS Other irrigating solutions |
| ATC | C05BB56 | CARDIOVASCULAR SYSTEM VASOPROTECTIVES ANTIVARICOSE THERAPY Sclerosing agents for local injection |
| ATC | V04CA02 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Tests for diabetes |
| ATC | V06DC01 | VARIOUS GENERAL NUTRIENTS OTHER NUTRIENTS Carbohydrates |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolite |
| CHEBI has role | CHEBI:75772 | bakers yeast metabolite |
| CHEBI has role | CHEBI:76971 | E.coli metabolites |
| CHEBI has role | CHEBI:77746 | H. sapiens metabolites |
| MeSH PA | D005421 | Flavoring Agents |
| MeSH PA | D005503 | Food Additives |
| MeSH PA | D013549 | Sweetening Agents |
| CHEBI has role | CHEBI:78675 | essential metabolite |
Drug Use (View source of the data)
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Hypoglycemia | indication | 302866003 | DOID:9993 |
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 11.87 | acidic |
| pKa2 | 13.08 | acidic |
| pKa3 | 13.91 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4019541 | VUID |
| N0000147647 | NUI |
| D00009 | KEGG_DRUG |
| 77938-63-7 | SECONDARY_CAS_RN |
| 4017760 | VANDF |
| 4019541 | VANDF |
| C0017725 | UMLSCUI |
| CHEBI:4167 | CHEBI |
| GLO | PDB_CHEM_ID |
| CHEMBL1222250 | ChEMBL_ID |
| CHEMBL1614854 | ChEMBL_ID |
| D005947 | MESH_DESCRIPTOR_UI |
| DB09341 | DRUGBANK_ID |
| 4536 | IUPHAR_LIGAND_ID |
| LX22YL083G | UNII |
| 5793 | PUBCHEM_CID |
| DB01914 | DRUGBANK_ID |
| 1299920 | RXNORM |
| 11133 | MMSL |
| 4567 | MMSL |
| 4787 | MMSL |
| 71873 | MMSL |
| 71874 | MMSL |
| 9763 | MMSL |
| d00595 | MMSL |
| 000915 | NDDF |
| 002597 | NDDF |
| 111138002 | SNOMEDCT_US |
| 67079006 | SNOMEDCT_US |
| 725859007 | SNOMEDCT_US |
| 768547002 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-1290 | INJECTION, SOLUTION | 70 g | INTRAVENOUS | UNAPPROVED DRUG OTHER | 24 sections |
| Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-1510 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | NDA | 24 sections |
| MYOCARD-DX | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-1840 | INJECTION | 5 g | INTRAVENOUS | EXPORT ONLY | 20 sections |
| MYOCARD-DX | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-1880 | INJECTION | 5 g | INTRAVENOUS | EXPORT ONLY | 20 sections |
| Isolyte P in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-7730 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 23 sections |
| Dextrose in Lactated Ringers | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0264-7751 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 22 sections |
| Theophylline in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9554 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 27 sections |
| Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9567 | INJECTION | 5 g | INTRAVENOUS | NDA | 19 sections |
| Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9577 | INJECTION | 5 g | INTRAVENOUS | NDA | 19 sections |
| Heparin Sodium in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9587 | INJECTION | 5 g | INTRAVENOUS | NDA | 19 sections |
| Lidocaine Hydrochloride and Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9594 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 23 sections |
| Lidocaine Hydrochloride and Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0264-9598 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 23 sections |
| DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0017 | INJECTION, SOLUTION | 50 g | INTRAVENOUS | NDA | 21 sections |
| DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0023 | INJECTION, SOLUTION | 100 g | INTRAVENOUS | NDA | 21 sections |
| DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0062 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0066 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0070 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0073 | INJECTION, SOLUTION | 2.50 g | INTRAVENOUS | NDA | 21 sections |
| DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0074 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0077 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0078 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0081 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0082 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0085 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0338-0089 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| Lactated Ringers and Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0338-0125 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 18 sections |
| Dextrose and Electrolyte No. 48 | HUMAN PRESCRIPTION DRUG LABEL | 6 | 0338-0143 | INJECTION | 5 g | INTRAVENOUS | NDA | 19 sections |
| Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-0551 | INJECTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| Potassium Chloride in Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0338-0603 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |
| Potassium Chloride in Dextrose and Sodium Chloride | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0338-0663 | INJECTION, SOLUTION | 5 g | INTRAVENOUS | NDA | 21 sections |