Stem definition | Drug id | CAS RN |
---|---|---|
831 | 21888-98-2 |
Dose | Unit | Route |
---|---|---|
0.50 | mg | O |
0.13 | mg | P |
None
None
None
None
None
None
Source | Code | Description |
---|---|---|
ATC | N04AA08 | NERVOUS SYSTEM ANTI-PARKINSON DRUGS ANTICHOLINERGIC AGENTS Tertiary amines |
MeSH PA | D018726 | Anti-Dyskinesia Agents |
MeSH PA | D000978 | Antiparkinson Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D018678 | Cholinergic Agents |
MeSH PA | D018680 | Cholinergic Antagonists |
MeSH PA | D018727 | Muscarinic Antagonists |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D010276 | Parasympatholytics |
MeSH PA | D018373 | Peripheral Nervous System Agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Neuroleptic-induced Parkinsonism | indication | 72820004 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 9.81 | acidic |
pKa2 | 8.64 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M2 | GPCR | ANTAGONIST | Ki | 8.90 | IUPHAR | IUPHAR | |||
Muscarinic acetylcholine receptor M2 | GPCR | ANTAGONIST | Ki | 8.80 | IUPHAR | ||||
Muscarinic acetylcholine receptor | GPCR | IC50 | 8.48 | CHEMBL |
ID | Source |
---|---|
N0000167212 | NUI |
D03711 | KEGG_DRUG |
3267 | RXNORM |
C0011785 | UMLSCUI |
CHEBI:135531 | CHEBI |
CHEMBL1908364 | ChEMBL_ID |
DB08997 | DRUGBANK_ID |
D003909 | MESH_DESCRIPTOR_UI |
30843 | PUBCHEM_CID |
354 | IUPHAR_LIGAND_ID |
2726 | INN_ID |
43477QYX3D | UNII |
007865 | NDDF |
None