demecarium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| quaternary ammonium compounds | 801 | 56-94-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
major descriptor (65-85); on-line search AMMONIUM COMPOUNDS (66-85); Index Medicus search DEMECARIUM BROMIDE (65-85)
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.10 | ml | None |
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Aug. 5, 1959 | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | S01EB04 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIGLAUCOMA PREPARATIONS AND MIOTICS Parasympathomimetics |
| CHEBI has role | CHEBI:37733 | EC 3.1.1.8 inhibitor |
| CHEBI has role | CHEBI:38462 | acetylcholinesterase inhibitors |
| MeSH PA | D018678 | Cholinergic Agents |
| MeSH PA | D002800 | Cholinesterase Inhibitors |
| MeSH PA | D004791 | Enzyme Inhibitors |
| MeSH PA | D018377 | Neurotransmitter Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Acetylcholinesterase | Enzyme | INHIBITOR | DRUGBANK | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 4017960 | VUID |
| N0000179097 | NUI |
| D00667 | KEGG_DRUG |
| 107771 | RXNORM |
| 4017960 | VANDF |
| 4019706 | VANDF |
| C0360174 | UMLSCUI |
| CHEBI:4391 | CHEBI |
| CHEMBL1201229 | ChEMBL_ID |
| CHEMBL1200514 | ChEMBL_ID |
| DB00944 | DRUGBANK_ID |
| C100193 | MESH_SUPPLEMENTAL_RECORD_UI |
| ILP8XJ8R5K | UNII |
| 5966 | PUBCHEM_CID |
| 4542 | MMSL |
| 001710 | NDDF |
| 372827003 | SNOMEDCT_US |
| 49145008 | SNOMEDCT_US |
| 70934008 | SNOMEDCT_US |
| 769 | INN_ID |
| 16505-84-3 | SECONDARY_CAS_RN |
Pharmaceutical products:
None