cycrimine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	763	77-39-4

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

cycrimine
cycrimine hydrochloride
pagitane
cycrimine HCl

Molecular weight: 287.45
Formula: C19H29NO
CLOGP: 4.59
LIPINSKI: 0
HAC: 2
HDO: 1
TPSA: 23.47
ALOGS: -4.50
ROTB: 5

Status: OFM

Legend:
OFP - off patent
OFM - off market
ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA	LILLY

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
CHEBI has role	CHEBI:48407	antiparkinson agent
CHEBI has role	CHEBI:48876	muscarinic antagonists
CHEBI has role	CHEBI:66956	antidyskinetic agent

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Parkinson's disease	indication	49049000	DOID:14330

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.23	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Muscarinic acetylcholine receptor M1	GPCR	P11229	ACM1_HUMAN	ANTAGONIST				WOMBAT-PK	CHEMBL

External reference:

ID	Source
126-02-3	SECONDARY_CAS_RN
22037	RXNORM
C0056835	UMLSCUI
CHEBI:59692	CHEBI
CHEMBL1201227	ChEMBL_ID
DB00942	DRUGBANK_ID
CHEMBL1200828	ChEMBL_ID
C012262	MESH_SUPPLEMENTAL_RECORD_UI
2911	PUBCHEM_CID
289	INN_ID
543567RFQQ	UNII
001642	NDDF
004665	NDDF
71108007	SNOMEDCT_US

Pharmaceutical products:

None