acetylleucine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
71 99-15-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • acetylleucine
  • (S)-2-Acetamido-4-methylpentanoic acid
  • Acetyl-L-leucine
  • N-Acetylleucine
used for treating vestibular-related imbalance and vertigo
  • Molecular weight: 173.21
  • Formula: C8H15NO3
  • CLOGP: 0.86
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 66.40
  • ALOGS: -1.20
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC N07CA04 NERVOUS SYSTEM
OTHER NERVOUS SYSTEM DRUGS
ANTIVERTIGO PREPARATIONS
Antivertigo preparations
CHEBI has role CHEBI:25212 metabolites

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.9 acidic
pKa2 13.57 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
K76S41V71X UNII
D07350 KEGG_DRUG
C0256552 UMLSCUI
CHEBI:166830 CHEBI
CHEMBL56021 ChEMBL_ID
CHEMBL1875805 ChEMBL_ID
70912 PUBCHEM_CID
DB13226 DRUGBANK_ID
5209 INN_ID
C088117 MESH_SUPPLEMENTAL_RECORD_UI
005881 NDDF
735136009 SNOMEDCT_US

Pharmaceutical products:

None