cloperastine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
707 3703-76-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hustazol
  • cloperastine hydrochloride
  • cloperastine fendizoate
  • cloperastine
  • cloperastine HCl
  • Molecular weight: 329.87
  • Formula: C20H24ClNO
  • CLOGP: 5.38
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 0
  • TPSA: 12.47
  • ALOGS: -5.63
  • ROTB: 6

Drug dosage:

DoseUnitRoute
60 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R05DB21 RESPIRATORY SYSTEM
COUGH AND COLD PREPARATIONS
COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
Other cough suppressants

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.7 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Solute carrier family 22 member 1 Transporter IC50 4.83 CHEMBL

External reference:

IDSource
D01569 KEGG_DRUG
14984-68-0 SECONDARY_CAS_RN
85187-37-7 SECONDARY_CAS_RN
2104180 RXNORM
C0055930 UMLSCUI
CHEBI:31419 CHEBI
CHEMBL415087 ChEMBL_ID
DB09002 DRUGBANK_ID
C040282 MESH_SUPPLEMENTAL_RECORD_UI
2805 PUBCHEM_CID
2423 INN_ID
69M5L7BXEK UNII
018216 NDDF
018217 NDDF
698092008 SNOMEDCT_US
708181006 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
FACOL CLASSIC ONE HUMAN OTC DRUG LABEL 6 72689-0013 CAPSULE 8 mg ORAL unapproved drug other 7 sections