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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
clopamide 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
diuretics, sulfamoylbenzoic acid derivatives
706
636-54-4
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
brinedine
clopamide
chlosudimeprimyl
clopamidum
brinaldix
A sulfamoylbenzamide piperidine. It is considered a thiazide-like diuretic.
Molecular weight: 345.84
Formula: C14H20ClN3O3S
CLOGP: 2.37
LIPINSKI: 0
HAC: 6
HDO: 2
TPSA: 92.50
ALOGS: -3.40
ROTB: 3
Drug dosage:
Dose
Unit
Route
10
mg
O
10
mg
O
ADMET properties:
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Property
Value
Reference
BDDCS (Biopharmaceutical Drug Disposition Classification System)
3
Hosey CM, Chan R, Benet LZ
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
C03BA03
CARDIOVASCULAR SYSTEM
DIURETICS
LOW-CEILING DIURETICS, EXCL. THIAZIDES
Sulfonamides, plain
ATC
C03BB03
CARDIOVASCULAR SYSTEM
DIURETICS
LOW-CEILING DIURETICS, EXCL. THIAZIDES
Sulfonamides and potassium in combination
MeSH PA
D004232
Diuretics
MeSH PA
D045283
Natriuretic Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
8.61
acidic
pKa2
11.42
acidic
pKa3
3.76
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
003711
NDDF
12492
PUBCHEM_CID
1517
INN_ID
17S83WON0I
UNII
2603
RXNORM
395940005
SNOMEDCT_US
429462003
SNOMEDCT_US
C0009025
UMLSCUI
CHEBI:94521
CHEBI
CHEMBL1361347
ChEMBL_ID
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Pharmaceutical products:
None
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clopamide