Stem definition | Drug id | CAS RN |
---|---|---|
antibacterials, nalidixic acid derivatives | 659 | 85721-33-1 |
Dose | Unit | Route |
---|---|---|
1 | g | O |
0.80 | g | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 4 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.15 mg/mL | Bocci G, Oprea TI, Benet LZ |
EoM (Fraction excreted unchanged in urine) | 65 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 34.49 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 60 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 2.10 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 8.30 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.70 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 3.80 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Oct. 22, 1987 | FDA | BAYER HLTHCARE |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 1323.83 | 9.68 | 2311 | 127182 | 308376 | 63051153 |
Tendon pain | 665.97 | 9.68 | 252 | 129241 | 3074 | 63356455 |
Tendonitis | 536.27 | 9.68 | 389 | 129104 | 19226 | 63340303 |
Abortion spontaneous | 419.02 | 9.68 | 499 | 128994 | 46696 | 63312833 |
Drug reaction with eosinophilia and systemic symptoms | 372.31 | 9.68 | 400 | 129093 | 33436 | 63326093 |
Pemphigus | 348.68 | 9.68 | 5 | 129488 | 183721 | 63175808 |
Hand deformity | 304.04 | 9.68 | 4 | 129489 | 159453 | 63200076 |
Tendon disorder | 285.89 | 9.68 | 167 | 129326 | 5676 | 63353853 |
Glossodynia | 284.34 | 9.68 | 21 | 129472 | 178855 | 63180674 |
Drug interaction | 278.46 | 9.68 | 1062 | 128431 | 228069 | 63131460 |
Tendon rupture | 273.28 | 9.68 | 184 | 129309 | 8055 | 63351474 |
Pathogen resistance | 254.16 | 9.68 | 160 | 129333 | 6238 | 63353291 |
Synovitis | 251.51 | 9.68 | 40 | 129453 | 186878 | 63172651 |
Toxic epidermal necrolysis | 229.96 | 9.68 | 271 | 129222 | 25063 | 63334466 |
Systemic lupus erythematosus | 224.81 | 9.68 | 73 | 129420 | 208845 | 63150684 |
Anti-cyclic citrullinated peptide antibody positive | 216.91 | 9.68 | 4 | 129489 | 116208 | 63243321 |
Tubulointerstitial nephritis | 216.64 | 9.68 | 234 | 129259 | 19669 | 63339860 |
Rheumatoid arthritis | 215.66 | 9.68 | 125 | 129368 | 253694 | 63105835 |
Pericarditis | 207.50 | 9.68 | 16 | 129477 | 131563 | 63227966 |
Arthropathy | 194.70 | 9.68 | 119 | 129374 | 234673 | 63124856 |
Acute kidney injury | 193.19 | 9.68 | 1052 | 128441 | 262363 | 63097166 |
Clostridium difficile colitis | 183.33 | 9.68 | 218 | 129275 | 20351 | 63339178 |
Contraindicated product administered | 174.01 | 9.68 | 115 | 129378 | 217533 | 63141996 |
Drug ineffective | 168.49 | 9.68 | 1347 | 128146 | 1043418 | 62316111 |
Alopecia | 167.34 | 9.68 | 269 | 129224 | 337267 | 63022262 |
Therapeutic product effect decreased | 162.81 | 9.68 | 96 | 129397 | 193091 | 63166438 |
Duodenal ulcer perforation | 162.74 | 9.68 | 3 | 129490 | 87206 | 63272323 |
Clostridium difficile infection | 155.30 | 9.68 | 244 | 129249 | 29678 | 63329851 |
Rheumatoid factor positive | 153.22 | 9.68 | 4 | 129489 | 84402 | 63275127 |
Helicobacter infection | 152.96 | 9.68 | 9 | 129484 | 92776 | 63266753 |
Stevens-Johnson syndrome | 148.70 | 9.68 | 217 | 129276 | 24733 | 63334796 |
Wound | 147.95 | 9.68 | 74 | 129419 | 163189 | 63196340 |
Joint swelling | 130.16 | 9.68 | 298 | 129195 | 327368 | 63032161 |
Infusion related reaction | 124.12 | 9.68 | 193 | 129300 | 245328 | 63114201 |
Discomfort | 122.56 | 9.68 | 97 | 129396 | 167277 | 63192252 |
Drug intolerance | 120.74 | 9.68 | 283 | 129210 | 308378 | 63051151 |
Tinnitus | 114.76 | 9.68 | 236 | 129257 | 35392 | 63324137 |
Treatment failure | 109.90 | 9.68 | 147 | 129346 | 198896 | 63160633 |
Muscle injury | 108.74 | 9.68 | 6 | 129487 | 65339 | 63294190 |
Myalgia | 101.09 | 9.68 | 576 | 128917 | 145953 | 63213576 |
Total lung capacity increased | 97.38 | 9.68 | 60 | 129433 | 2250 | 63357279 |
Dysbiosis | 97.34 | 9.68 | 44 | 129449 | 862 | 63358667 |
Folliculitis | 96.91 | 9.68 | 14 | 129479 | 70303 | 63289226 |
Completed suicide | 96.26 | 9.68 | 93 | 129400 | 145580 | 63213949 |
Anal fistula | 96.05 | 9.68 | 70 | 129423 | 3481 | 63356048 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 95.82 | 9.68 | 57 | 129436 | 2004 | 63357525 |
Psoriatic arthropathy | 94.86 | 9.68 | 34 | 129459 | 91486 | 63268043 |
Tendon injury | 90.84 | 9.68 | 54 | 129439 | 1896 | 63357633 |
Rash maculo-papular | 89.74 | 9.68 | 200 | 129293 | 31696 | 63327833 |
Tendon discomfort | 87.28 | 9.68 | 27 | 129466 | 168 | 63359361 |
Anxiety | 87.23 | 9.68 | 749 | 128744 | 216792 | 63142737 |
Fall | 85.98 | 9.68 | 460 | 129033 | 391874 | 62967655 |
Abdominal pain | 84.67 | 9.68 | 943 | 128550 | 292513 | 63067016 |
Cholecystitis chronic | 84.49 | 9.68 | 105 | 129388 | 10256 | 63349273 |
Female genital tract fistula | 84.23 | 9.68 | 90 | 129403 | 7469 | 63352060 |
Dermatitis exfoliative | 83.05 | 9.68 | 77 | 129416 | 5382 | 63354147 |
Fistula | 82.64 | 9.68 | 104 | 129389 | 10289 | 63349240 |
Product use issue | 82.37 | 9.68 | 207 | 129286 | 220313 | 63139216 |
Drug resistance | 81.15 | 9.68 | 158 | 129335 | 22775 | 63336754 |
Early retirement | 79.59 | 9.68 | 16 | 129477 | 4 | 63359525 |
Loss of employment | 78.96 | 9.68 | 52 | 129441 | 2192 | 63357337 |
Swelling | 78.28 | 9.68 | 293 | 129200 | 275085 | 63084444 |
Hepatic enzyme increased | 76.27 | 9.68 | 189 | 129304 | 202139 | 63157390 |
Acute generalised exanthematous pustulosis | 75.72 | 9.68 | 103 | 129390 | 10996 | 63348533 |
Abdominal discomfort | 74.92 | 9.68 | 368 | 129125 | 320517 | 63039012 |
Panic attack | 73.18 | 9.68 | 149 | 129344 | 22182 | 63337347 |
Skin candida | 72.36 | 9.68 | 44 | 129449 | 1611 | 63357918 |
Death | 72.36 | 9.68 | 457 | 129036 | 373924 | 62985605 |
Maternal exposure during pregnancy | 72.18 | 9.68 | 220 | 129273 | 219842 | 63139687 |
Colitis | 71.63 | 9.68 | 240 | 129253 | 48288 | 63311241 |
Peripheral swelling | 71.08 | 9.68 | 290 | 129203 | 265652 | 63093877 |
Multiple organ dysfunction syndrome | 68.68 | 9.68 | 263 | 129230 | 56489 | 63303040 |
Geotrichum infection | 67.22 | 9.68 | 28 | 129465 | 446 | 63359083 |
Hip arthroplasty | 66.80 | 9.68 | 9 | 129484 | 47637 | 63311892 |
Nasopharyngitis | 66.24 | 9.68 | 280 | 129213 | 253977 | 63105552 |
Musculoskeletal injury | 63.17 | 9.68 | 19 | 129474 | 106 | 63359423 |
Connective tissue disorder | 62.97 | 9.68 | 38 | 129455 | 1372 | 63358157 |
Burning sensation | 62.48 | 9.68 | 248 | 129245 | 54159 | 63305370 |
Disturbance in attention | 61.89 | 9.68 | 195 | 129298 | 37994 | 63321535 |
Therapeutic product effect incomplete | 60.59 | 9.68 | 101 | 129392 | 124955 | 63234574 |
Urinary tract infection | 60.43 | 9.68 | 814 | 128679 | 263870 | 63095659 |
Impaired healing | 59.38 | 9.68 | 73 | 129420 | 102469 | 63257060 |
Joint noise | 59.31 | 9.68 | 58 | 129435 | 4334 | 63355195 |
Ill-defined disorder | 57.79 | 9.68 | 49 | 129444 | 81706 | 63277823 |
Febrile neutropenia | 57.35 | 9.68 | 426 | 129067 | 118023 | 63241506 |
Trimethylaminuria | 57.09 | 9.68 | 19 | 129474 | 154 | 63359375 |
Paraesthesia | 56.98 | 9.68 | 529 | 128964 | 156437 | 63203092 |
Intentional overdose | 56.77 | 9.68 | 41 | 129452 | 74111 | 63285418 |
Frequent bowel movements | 56.68 | 9.68 | 137 | 129356 | 22885 | 63336644 |
Injection site pain | 56.48 | 9.68 | 112 | 129381 | 129688 | 63229841 |
Type 2 diabetes mellitus | 56.25 | 9.68 | 30 | 129463 | 63838 | 63295691 |
Pyrexia | 55.66 | 9.68 | 1303 | 128190 | 469175 | 62890354 |
Pseudomembranous colitis | 55.47 | 9.68 | 48 | 129445 | 3064 | 63356465 |
Vaginal flatulence | 55.10 | 9.68 | 49 | 129444 | 3244 | 63356285 |
Anal abscess | 54.90 | 9.68 | 57 | 129436 | 4575 | 63354954 |
Neuropathy peripheral | 54.57 | 9.68 | 408 | 129085 | 113259 | 63246270 |
Eosinophilia | 54.52 | 9.68 | 134 | 129359 | 22622 | 63336907 |
Diarrhoea | 54.00 | 9.68 | 1871 | 127622 | 713495 | 62646034 |
Nasal polyps | 53.79 | 9.68 | 64 | 129429 | 5975 | 63353554 |
Renal tubular necrosis | 53.67 | 9.68 | 91 | 129402 | 11787 | 63347742 |
Torsade de pointes | 53.48 | 9.68 | 97 | 129396 | 13254 | 63346275 |
Segmental diverticular colitis | 53.03 | 9.68 | 18 | 129475 | 156 | 63359373 |
Nephritis allergic | 52.37 | 9.68 | 19 | 129474 | 204 | 63359325 |
Pedal pulse abnormal | 52.24 | 9.68 | 18 | 129475 | 164 | 63359365 |
Chronic kidney disease | 52.18 | 9.68 | 207 | 129286 | 45191 | 63314338 |
Diverticulitis | 51.76 | 9.68 | 188 | 129305 | 39369 | 63320160 |
Vulvovaginal burning sensation | 51.29 | 9.68 | 39 | 129454 | 2070 | 63357459 |
Device expulsion | 50.40 | 9.68 | 6 | 129487 | 34916 | 63324613 |
Weight increased | 49.48 | 9.68 | 320 | 129173 | 260472 | 63099057 |
Pseudomonas infection | 49.48 | 9.68 | 85 | 129408 | 11128 | 63348401 |
Oesophageal spasm | 49.36 | 9.68 | 45 | 129448 | 3078 | 63356451 |
Hallucination | 49.22 | 9.68 | 232 | 129261 | 54585 | 63304944 |
Infective pulmonary exacerbation of cystic fibrosis | 47.27 | 9.68 | 73 | 129420 | 8744 | 63350785 |
Blood cholesterol increased | 46.42 | 9.68 | 75 | 129418 | 93957 | 63265572 |
Proctitis | 45.75 | 9.68 | 56 | 129437 | 5385 | 63354144 |
Neutropenia | 44.44 | 9.68 | 549 | 128944 | 174456 | 63185073 |
Nervous system disorder | 44.42 | 9.68 | 110 | 129383 | 18656 | 63340873 |
Mucosal inflammation | 43.89 | 9.68 | 201 | 129292 | 46727 | 63312802 |
Emotional distress | 43.70 | 9.68 | 156 | 129337 | 32393 | 63327136 |
Therapeutic response decreased | 43.33 | 9.68 | 37 | 129456 | 61488 | 63298041 |
Calcium ionised decreased | 42.97 | 9.68 | 18 | 129475 | 291 | 63359238 |
Hallucinations, mixed | 42.72 | 9.68 | 51 | 129442 | 4778 | 63354751 |
Thrombocytopenia | 42.71 | 9.68 | 484 | 129009 | 150673 | 63208856 |
Injection site erythema | 42.33 | 9.68 | 65 | 129428 | 83109 | 63276420 |
Osteoporosis | 42.22 | 9.68 | 33 | 129460 | 57305 | 63302224 |
Abscess | 41.91 | 9.68 | 100 | 129393 | 16568 | 63342961 |
Intentional product use issue | 41.79 | 9.68 | 128 | 129365 | 127764 | 63231765 |
Cholelithiasis | 41.72 | 9.68 | 189 | 129304 | 43736 | 63315793 |
Injection site reaction | 41.45 | 9.68 | 35 | 129458 | 58489 | 63301040 |
Food intolerance | 41.37 | 9.68 | 42 | 129451 | 3283 | 63356246 |
Product dose omission issue | 41.20 | 9.68 | 294 | 129199 | 234019 | 63125510 |
Sarcoidosis | 41.07 | 9.68 | 61 | 129432 | 7061 | 63352468 |
Cystitis | 39.75 | 9.68 | 219 | 129274 | 54772 | 63304757 |
Mobility decreased | 39.07 | 9.68 | 122 | 129371 | 121037 | 63238492 |
Nasal oedema | 38.91 | 9.68 | 29 | 129464 | 1493 | 63358036 |
Muscle atrophy | 38.79 | 9.68 | 59 | 129434 | 6974 | 63352555 |
Lymphoedema | 38.29 | 9.68 | 78 | 129415 | 11614 | 63347915 |
Pancytopenia | 37.87 | 9.68 | 332 | 129161 | 96601 | 63262928 |
Sepsis | 37.86 | 9.68 | 478 | 129015 | 152645 | 63206884 |
Oesophageal pain | 37.64 | 9.68 | 42 | 129451 | 3659 | 63355870 |
Pouchitis | 37.34 | 9.68 | 19 | 129474 | 488 | 63359041 |
Abdominal pain lower | 37.01 | 9.68 | 126 | 129367 | 25552 | 63333977 |
Aspergillus infection | 36.56 | 9.68 | 62 | 129431 | 8031 | 63351498 |
Knee arthroplasty | 36.49 | 9.68 | 34 | 129459 | 54172 | 63305357 |
Toxic skin eruption | 36.47 | 9.68 | 81 | 129412 | 12804 | 63346725 |
Radiculopathy | 36.33 | 9.68 | 64 | 129429 | 8547 | 63350982 |
Pulmonary pain | 36.17 | 9.68 | 40 | 129453 | 3450 | 63356079 |
Stomatitis | 35.94 | 9.68 | 153 | 129340 | 138572 | 63220957 |
Rhinitis allergic | 35.79 | 9.68 | 76 | 129417 | 11651 | 63347878 |
Impaired work ability | 35.77 | 9.68 | 97 | 129396 | 17378 | 63342151 |
Fatigue | 35.68 | 9.68 | 1466 | 128027 | 886562 | 62472967 |
Flank pain | 35.53 | 9.68 | 93 | 129400 | 16317 | 63343212 |
Clostridium test positive | 35.46 | 9.68 | 38 | 129455 | 3163 | 63356366 |
Abnormal palmar/plantar creases | 35.38 | 9.68 | 10 | 129483 | 43 | 63359486 |
Sinusitis | 35.33 | 9.68 | 294 | 129199 | 226359 | 63133170 |
Factor V deficiency | 35.22 | 9.68 | 11 | 129482 | 71 | 63359458 |
Lividity | 35.12 | 9.68 | 15 | 129478 | 255 | 63359274 |
Procedural anxiety | 34.88 | 9.68 | 21 | 129472 | 755 | 63358774 |
Prescribed overdose | 34.85 | 9.68 | 13 | 129480 | 34140 | 63325389 |
Erythema | 34.67 | 9.68 | 527 | 128966 | 175224 | 63184305 |
Psoriasis | 34.51 | 9.68 | 79 | 129414 | 86878 | 63272651 |
Grip strength decreased | 34.31 | 9.68 | 3 | 129490 | 22284 | 63337245 |
Musculoskeletal stiffness | 34.25 | 9.68 | 228 | 129265 | 184390 | 63175139 |
Irritable bowel syndrome | 34.24 | 9.68 | 73 | 129420 | 82339 | 63277190 |
Pyelonephritis | 33.74 | 9.68 | 96 | 129397 | 17682 | 63341847 |
Thermal burn | 33.74 | 9.68 | 51 | 129442 | 5995 | 63353534 |
Crystal nephropathy | 33.69 | 9.68 | 22 | 129471 | 914 | 63358615 |
Ectropion | 33.33 | 9.68 | 13 | 129480 | 173 | 63359356 |
Malignant neoplasm progression | 33.08 | 9.68 | 74 | 129419 | 82047 | 63277482 |
Mitochondrial cytopathy | 33.05 | 9.68 | 14 | 129479 | 233 | 63359296 |
Megacolon | 33.05 | 9.68 | 29 | 129464 | 1886 | 63357643 |
Cytokine release syndrome | 32.93 | 9.68 | 83 | 129410 | 14231 | 63345298 |
Drug abuse | 32.91 | 9.68 | 61 | 129432 | 72457 | 63287072 |
Klebsiella infection | 32.75 | 9.68 | 61 | 129432 | 8505 | 63351024 |
Suicide attempt | 32.57 | 9.68 | 46 | 129447 | 60872 | 63298657 |
Adverse event | 32.31 | 9.68 | 55 | 129438 | 67504 | 63292025 |
Excessive eye blinking | 31.86 | 9.68 | 24 | 129469 | 1256 | 63358273 |
Hepatitis cholestatic | 31.48 | 9.68 | 53 | 129440 | 6825 | 63352704 |
Live birth | 31.21 | 9.68 | 7 | 129486 | 25623 | 63333906 |
Gastroenteritis pseudomonas | 31.18 | 9.68 | 6 | 129487 | 0 | 63359529 |
Collagen disorder | 31.16 | 9.68 | 13 | 129480 | 208 | 63359321 |
Pulmonary eosinophilia | 31.11 | 9.68 | 15 | 129478 | 342 | 63359187 |
Vaginal discharge | 30.88 | 9.68 | 62 | 129431 | 9136 | 63350393 |
Hyperacusis | 30.60 | 9.68 | 29 | 129464 | 2084 | 63357445 |
Fistula discharge | 30.60 | 9.68 | 22 | 129471 | 1071 | 63358458 |
Bronchiectasis | 30.48 | 9.68 | 87 | 129406 | 16055 | 63343474 |
Factor V inhibition | 30.47 | 9.68 | 12 | 129481 | 164 | 63359365 |
Haematochezia | 30.25 | 9.68 | 200 | 129293 | 53344 | 63306185 |
Oliguria | 30.14 | 9.68 | 61 | 129432 | 9040 | 63350489 |
Pregnancy | 30.02 | 9.68 | 19 | 129474 | 36817 | 63322712 |
Candida infection | 29.98 | 9.68 | 126 | 129367 | 28225 | 63331304 |
Anal fissure | 29.96 | 9.68 | 41 | 129452 | 4402 | 63355127 |
Anorectal ulcer | 29.95 | 9.68 | 9 | 129484 | 50 | 63359479 |
Injection site bruising | 29.76 | 9.68 | 25 | 129468 | 41885 | 63317644 |
Non-consummation | 29.51 | 9.68 | 9 | 129484 | 53 | 63359476 |
Fungaemia | 29.26 | 9.68 | 30 | 129463 | 2373 | 63357156 |
Pain | 29.20 | 9.68 | 1225 | 128268 | 739403 | 62620126 |
Potentiating drug interaction | 29.07 | 9.68 | 40 | 129453 | 4316 | 63355213 |
Mineral deficiency | 29.06 | 9.68 | 7 | 129486 | 13 | 63359516 |
Muscle twitching | 28.78 | 9.68 | 97 | 129396 | 19571 | 63339958 |
Exercise tolerance decreased | 28.75 | 9.68 | 45 | 129448 | 5452 | 63354077 |
Accidental exposure to product | 28.70 | 9.68 | 10 | 129483 | 27395 | 63332134 |
Injection site swelling | 28.45 | 9.68 | 33 | 129460 | 47539 | 63311990 |
Coma | 28.45 | 9.68 | 55 | 129438 | 64309 | 63295220 |
Hypersensitivity | 28.36 | 9.68 | 423 | 129070 | 292262 | 63067267 |
Depersonalisation/derealisation disorder | 28.25 | 9.68 | 23 | 129470 | 1349 | 63358180 |
Biliary dyskinesia | 27.81 | 9.68 | 31 | 129462 | 2698 | 63356831 |
Therapy non-responder | 27.72 | 9.68 | 72 | 129421 | 75829 | 63283700 |
Bacterial colitis | 27.59 | 9.68 | 9 | 129484 | 68 | 63359461 |
Muscle contractions involuntary | 27.57 | 9.68 | 29 | 129464 | 2363 | 63357166 |
Photosensitivity reaction | 27.52 | 9.68 | 80 | 129413 | 14914 | 63344615 |
Feeding intolerance | 27.39 | 9.68 | 18 | 129475 | 756 | 63358773 |
COVID-19 | 27.33 | 9.68 | 128 | 129365 | 112975 | 63246554 |
Paraesthesia oral | 27.32 | 9.68 | 94 | 129399 | 19162 | 63340367 |
Injection site pruritus | 27.31 | 9.68 | 31 | 129462 | 45085 | 63314444 |
Fat tissue decreased | 27.23 | 9.68 | 7 | 129486 | 19 | 63359510 |
Weight bearing difficulty | 27.18 | 9.68 | 30 | 129463 | 2582 | 63356947 |
Linear IgA disease | 27.12 | 9.68 | 23 | 129470 | 1428 | 63358101 |
Amyloid arthropathy | 26.86 | 9.68 | 16 | 129477 | 564 | 63358965 |
Neutropenic sepsis | 26.69 | 9.68 | 84 | 129409 | 16354 | 63343175 |
Vulvovaginal pruritus | 26.66 | 9.68 | 33 | 129460 | 3210 | 63356319 |
Vomiting | 26.54 | 9.68 | 1395 | 128098 | 558222 | 62801307 |
Moraxella test positive | 26.48 | 9.68 | 7 | 129486 | 22 | 63359507 |
Off label use | 26.47 | 9.68 | 1116 | 128377 | 673346 | 62686183 |
Basal cell carcinoma | 26.38 | 9.68 | 12 | 129481 | 27979 | 63331550 |
Cystic fibrosis | 26.23 | 9.68 | 33 | 129460 | 3263 | 63356266 |
Multiple sclerosis relapse | 25.52 | 9.68 | 37 | 129456 | 48441 | 63311088 |
Botulism | 25.44 | 9.68 | 11 | 129482 | 193 | 63359336 |
Injection site hyperaesthesia | 25.43 | 9.68 | 8 | 129485 | 53 | 63359476 |
Breast cancer | 25.40 | 9.68 | 37 | 129456 | 48346 | 63311183 |
Acinetobacter infection | 25.39 | 9.68 | 23 | 129470 | 1560 | 63357969 |
Gastrointestinal disorder | 25.39 | 9.68 | 160 | 129333 | 131079 | 63228450 |
Rectal abscess | 25.35 | 9.68 | 21 | 129472 | 1262 | 63358267 |
Fixed eruption | 25.00 | 9.68 | 20 | 129473 | 1144 | 63358385 |
Acute hepatic failure | 24.74 | 9.68 | 88 | 129405 | 18239 | 63341290 |
Rectal tube insertion | 24.62 | 9.68 | 6 | 129487 | 12 | 63359517 |
Phlebitis | 24.61 | 9.68 | 47 | 129446 | 6677 | 63352852 |
Cross sensitivity reaction | 24.54 | 9.68 | 26 | 129467 | 2136 | 63357393 |
Staphylococcal infection | 24.47 | 9.68 | 156 | 129337 | 41100 | 63318429 |
Nerve injury | 24.28 | 9.68 | 59 | 129434 | 9887 | 63349642 |
Blood creatinine increased | 24.22 | 9.68 | 280 | 129213 | 87564 | 63271965 |
Hepatitis infectious mononucleosis | 23.91 | 9.68 | 9 | 129484 | 108 | 63359421 |
Myopathy | 23.79 | 9.68 | 63 | 129430 | 11128 | 63348401 |
Rotator cuff syndrome | 23.79 | 9.68 | 71 | 129422 | 13431 | 63346098 |
Sciatica | 23.73 | 9.68 | 21 | 129472 | 34303 | 63325226 |
Toxicity to various agents | 23.72 | 9.68 | 358 | 129135 | 246892 | 63112637 |
Condition aggravated | 23.64 | 9.68 | 632 | 128861 | 401585 | 62957944 |
Septic shock | 23.37 | 9.68 | 223 | 129270 | 66406 | 63293123 |
Cardio-respiratory arrest | 23.36 | 9.68 | 55 | 129438 | 59904 | 63299625 |
Gastroenteritis staphylococcal | 23.30 | 9.68 | 8 | 129485 | 72 | 63359457 |
Rhinalgia | 23.26 | 9.68 | 22 | 129471 | 1577 | 63357952 |
Foot deformity | 23.21 | 9.68 | 14 | 129479 | 27839 | 63331690 |
Bladder pain | 23.14 | 9.68 | 26 | 129467 | 2282 | 63357247 |
Oral candidiasis | 23.08 | 9.68 | 100 | 129393 | 22698 | 63336831 |
Infrequent bowel movements | 23.04 | 9.68 | 20 | 129473 | 1282 | 63358247 |
Femur fracture | 22.85 | 9.68 | 31 | 129462 | 41725 | 63317804 |
Diaphragmatic rupture | 22.81 | 9.68 | 11 | 129482 | 251 | 63359278 |
Idiopathic intracranial hypertension | 22.78 | 9.68 | 29 | 129464 | 2902 | 63356627 |
Diabetes mellitus | 22.71 | 9.68 | 50 | 129443 | 55760 | 63303769 |
Incorrect route of product administration | 22.59 | 9.68 | 14 | 129479 | 27438 | 63332091 |
Respiratory tract oedema | 22.58 | 9.68 | 14 | 129479 | 531 | 63358998 |
Tendon necrosis | 22.53 | 9.68 | 5 | 129488 | 5 | 63359524 |
Epicondylitis | 22.43 | 9.68 | 25 | 129468 | 2175 | 63357354 |
Cardiac murmur | 22.39 | 9.68 | 73 | 129420 | 14479 | 63345050 |
Chemical burns of eye | 22.38 | 9.68 | 8 | 129485 | 82 | 63359447 |
Colitis ulcerative | 22.38 | 9.68 | 109 | 129384 | 25982 | 63333547 |
Bone marrow granuloma | 22.20 | 9.68 | 6 | 129487 | 21 | 63359508 |
Myoclonus | 22.11 | 9.68 | 77 | 129416 | 15791 | 63343738 |
Renal injury | 21.99 | 9.68 | 55 | 129438 | 9384 | 63350145 |
Meningitis candida | 21.56 | 9.68 | 7 | 129486 | 52 | 63359477 |
Swelling face | 21.55 | 9.68 | 211 | 129282 | 63264 | 63296265 |
Product contamination microbial | 21.53 | 9.68 | 10 | 129483 | 209 | 63359320 |
Dermatitis bullous | 21.34 | 9.68 | 51 | 129442 | 8457 | 63351072 |
Road traffic accident | 21.28 | 9.68 | 26 | 129467 | 36606 | 63322923 |
Arthritis | 21.06 | 9.68 | 144 | 129349 | 115777 | 63243752 |
Acute febrile neutrophilic dermatosis | 20.90 | 9.68 | 28 | 129465 | 2946 | 63356583 |
Neurotransmitter level altered | 20.79 | 9.68 | 4 | 129489 | 0 | 63359529 |
Tendon laxity | 20.79 | 9.68 | 4 | 129489 | 0 | 63359529 |
Renal vein compression | 20.79 | 9.68 | 4 | 129489 | 0 | 63359529 |
Prescribed underdose | 20.72 | 9.68 | 18 | 129475 | 29671 | 63329858 |
Enterococcal infection | 20.72 | 9.68 | 48 | 129445 | 7800 | 63351729 |
Confabulation | 20.72 | 9.68 | 11 | 129482 | 309 | 63359220 |
C-reactive protein abnormal | 20.71 | 9.68 | 39 | 129454 | 46057 | 63313472 |
Leukocytosis | 20.59 | 9.68 | 106 | 129387 | 25829 | 63333700 |
Cholestatic liver injury | 20.56 | 9.68 | 26 | 129467 | 2584 | 63356945 |
Hypomania | 20.46 | 9.68 | 42 | 129451 | 6288 | 63353241 |
Muscular weakness | 20.43 | 9.68 | 357 | 129136 | 121996 | 63237533 |
Swollen tongue | 20.27 | 9.68 | 131 | 129362 | 34669 | 63324860 |
Osteoarthritis | 20.15 | 9.68 | 113 | 129380 | 95230 | 63264299 |
Osteochondrosis | 20.13 | 9.68 | 19 | 129474 | 1358 | 63358171 |
Intestinal dilatation | 20.07 | 9.68 | 21 | 129472 | 1701 | 63357828 |
Adverse drug reaction | 19.98 | 9.68 | 89 | 129404 | 79625 | 63279904 |
Palpitations | 19.90 | 9.68 | 332 | 129161 | 112438 | 63247091 |
Head injury | 19.87 | 9.68 | 16 | 129477 | 27380 | 63332149 |
Tonsillar haemorrhage | 19.86 | 9.68 | 10 | 129483 | 251 | 63359278 |
Gallbladder rupture | 19.84 | 9.68 | 12 | 129481 | 435 | 63359094 |
Vitreous floaters | 19.77 | 9.68 | 40 | 129453 | 5926 | 63353603 |
Hepatic steatosis | 19.74 | 9.68 | 113 | 129380 | 28656 | 63330873 |
Medical device site pain | 19.65 | 9.68 | 9 | 129484 | 182 | 63359347 |
Single functional kidney | 19.62 | 9.68 | 11 | 129482 | 345 | 63359184 |
Vaccination site reaction | 19.58 | 9.68 | 8 | 129485 | 121 | 63359408 |
Hypercreatininaemia | 19.53 | 9.68 | 13 | 129480 | 558 | 63358971 |
Enterocolonic fistula | 19.44 | 9.68 | 6 | 129487 | 37 | 63359492 |
Diabetic macroangiopathy | 19.34 | 9.68 | 8 | 129485 | 125 | 63359404 |
Activated partial thromboplastin time prolonged | 19.13 | 9.68 | 43 | 129450 | 6850 | 63352679 |
Restlessness | 19.12 | 9.68 | 114 | 129379 | 29339 | 63330190 |
Product administration error | 19.02 | 9.68 | 11 | 129482 | 22386 | 63337143 |
Contusion | 18.93 | 9.68 | 205 | 129288 | 149839 | 63209690 |
Arrhythmia | 18.91 | 9.68 | 138 | 129355 | 38002 | 63321527 |
Long QT syndrome | 18.78 | 9.68 | 28 | 129465 | 3251 | 63356278 |
Escherichia infection | 18.74 | 9.68 | 63 | 129430 | 12691 | 63346838 |
Muscle tightness | 18.58 | 9.68 | 60 | 129433 | 11840 | 63347689 |
Drug-induced liver injury | 18.51 | 9.68 | 143 | 129350 | 40079 | 63319450 |
Mouth ulceration | 18.51 | 9.68 | 123 | 129370 | 32861 | 63326668 |
Jaundice cholestatic | 18.47 | 9.68 | 44 | 129449 | 7280 | 63352249 |
Immune effector cell-associated neurotoxicity syndrome | 18.44 | 9.68 | 23 | 129470 | 2254 | 63357275 |
Escherichia urinary tract infection | 18.39 | 9.68 | 60 | 129433 | 11902 | 63347627 |
Bacteriuria | 18.28 | 9.68 | 16 | 129477 | 1037 | 63358492 |
Product quality issue | 18.27 | 9.68 | 28 | 129465 | 35837 | 63323692 |
Product substitution issue | 18.25 | 9.68 | 5 | 129488 | 15991 | 63343538 |
Hypotony of eye | 18.12 | 9.68 | 8 | 129485 | 148 | 63359381 |
Sphingomonas paucimobilis infection | 18.10 | 9.68 | 6 | 129487 | 48 | 63359481 |
Infusion site streaking | 18.07 | 9.68 | 12 | 129481 | 513 | 63359016 |
Enterocutaneous fistula | 18.03 | 9.68 | 18 | 129475 | 1379 | 63358150 |
Roseola | 18.02 | 9.68 | 4 | 129489 | 4 | 63359525 |
Sensory processing disorder | 18.02 | 9.68 | 4 | 129489 | 4 | 63359525 |
Polyneuropathy | 17.96 | 9.68 | 68 | 129425 | 14521 | 63345008 |
Neuralgia | 17.90 | 9.68 | 102 | 129391 | 25824 | 63333705 |
Red blood cell sedimentation rate abnormal | 17.85 | 9.68 | 9 | 129484 | 19773 | 63339756 |
Heart rate decreased | 17.76 | 9.68 | 156 | 129337 | 45404 | 63314125 |
Anhedonia | 17.74 | 9.68 | 56 | 129437 | 10918 | 63348611 |
Blood bilirubin increased | 17.63 | 9.68 | 133 | 129360 | 37007 | 63322522 |
Extremity necrosis | 17.61 | 9.68 | 19 | 129474 | 1594 | 63357935 |
Chills | 17.58 | 9.68 | 327 | 129166 | 113051 | 63246478 |
Vulvovaginal swelling | 17.54 | 9.68 | 12 | 129481 | 539 | 63358990 |
Bladder trabeculation | 17.48 | 9.68 | 6 | 129487 | 54 | 63359475 |
Device related infection | 17.46 | 9.68 | 94 | 129399 | 23298 | 63336231 |
May-Thurner syndrome | 17.42 | 9.68 | 5 | 129488 | 23 | 63359506 |
Lip dry | 17.34 | 9.68 | 5 | 129488 | 15465 | 63344064 |
Skin oedema | 17.33 | 9.68 | 15 | 129478 | 958 | 63358571 |
Enterovesical fistula | 17.31 | 9.68 | 12 | 129481 | 551 | 63358978 |
Limb immobilisation | 17.28 | 9.68 | 6 | 129487 | 56 | 63359473 |
Product deposit | 17.28 | 9.68 | 9 | 129484 | 243 | 63359286 |
Seroconversion test positive | 17.25 | 9.68 | 5 | 129488 | 24 | 63359505 |
Faecal volume decreased | 17.15 | 9.68 | 8 | 129485 | 169 | 63359360 |
Gastrointestinal scarring | 17.01 | 9.68 | 10 | 129483 | 344 | 63359185 |
Bursitis | 16.94 | 9.68 | 31 | 129462 | 37010 | 63322519 |
Blister | 16.93 | 9.68 | 176 | 129317 | 129638 | 63229891 |
Fungal infection | 16.92 | 9.68 | 131 | 129362 | 36743 | 63322786 |
Henoch-Schonlein purpura | 16.91 | 9.68 | 16 | 129477 | 1147 | 63358382 |
Injection site warmth | 16.87 | 9.68 | 5 | 129488 | 15190 | 63344339 |
Neutrophilic dermatosis | 16.85 | 9.68 | 8 | 129485 | 176 | 63359353 |
Liver injury | 16.76 | 9.68 | 65 | 129428 | 60455 | 63299074 |
Herpes zoster | 16.74 | 9.68 | 99 | 129394 | 82363 | 63277166 |
Bulimia nervosa | 16.72 | 9.68 | 11 | 129482 | 463 | 63359066 |
Vanishing bile duct syndrome | 16.63 | 9.68 | 13 | 129480 | 719 | 63358810 |
Skin injury | 16.36 | 9.68 | 19 | 129474 | 1729 | 63357800 |
Loss of personal independence in daily activities | 16.15 | 9.68 | 124 | 129369 | 97166 | 63262363 |
Injury | 16.15 | 9.68 | 224 | 129269 | 73023 | 63286506 |
Haematoma | 16.14 | 9.68 | 124 | 129369 | 34696 | 63324833 |
Staphylococcal scalded skin syndrome | 16.13 | 9.68 | 7 | 129486 | 124 | 63359405 |
Symmetrical drug-related intertriginous and flexural exanthema | 16.10 | 9.68 | 11 | 129482 | 493 | 63359036 |
Cholecystitis acute | 16.06 | 9.68 | 45 | 129448 | 8215 | 63351314 |
Dysphonia | 16.03 | 9.68 | 158 | 129335 | 47456 | 63312073 |
Nerve degeneration | 16.02 | 9.68 | 6 | 129487 | 71 | 63359458 |
Intrauterine infection | 15.98 | 9.68 | 7 | 129486 | 127 | 63359402 |
Eczema asteatotic | 15.92 | 9.68 | 9 | 129484 | 287 | 63359242 |
Corneal deposits | 15.86 | 9.68 | 9 | 129484 | 289 | 63359240 |
Rhabdomyolysis | 15.86 | 9.68 | 148 | 129345 | 43803 | 63315726 |
Injection site streaking | 15.78 | 9.68 | 5 | 129488 | 34 | 63359495 |
Factor XIII Inhibition | 15.78 | 9.68 | 5 | 129488 | 34 | 63359495 |
Renal failure | 15.78 | 9.68 | 332 | 129161 | 117320 | 63242209 |
Recall phenomenon | 15.76 | 9.68 | 12 | 129481 | 638 | 63358891 |
Purple glove syndrome | 15.74 | 9.68 | 8 | 129485 | 205 | 63359324 |
Burnout syndrome | 15.70 | 9.68 | 8 | 129485 | 206 | 63359323 |
Infective aneurysm | 15.67 | 9.68 | 10 | 129483 | 399 | 63359130 |
Face oedema | 15.62 | 9.68 | 82 | 129411 | 20130 | 63339399 |
Eyelid oedema | 15.61 | 9.68 | 52 | 129441 | 10427 | 63349102 |
Injection site joint erythema | 15.59 | 9.68 | 3 | 129490 | 0 | 63359529 |
Hypertension | 15.58 | 9.68 | 442 | 129051 | 278861 | 63080668 |
Dysuria | 15.56 | 9.68 | 120 | 129373 | 33618 | 63325911 |
Type IV hypersensitivity reaction | 15.54 | 9.68 | 24 | 129469 | 2874 | 63356655 |
Hyperchlorhydria | 15.54 | 9.68 | 19 | 129474 | 1825 | 63357704 |
Post infection glomerulonephritis | 15.52 | 9.68 | 4 | 129489 | 11 | 63359518 |
Persistent corneal epithelial defect | 15.52 | 9.68 | 4 | 129489 | 11 | 63359518 |
Sleep disorder due to a general medical condition | 15.52 | 9.68 | 3 | 129490 | 12185 | 63347344 |
Rash pustular | 15.49 | 9.68 | 41 | 129452 | 7241 | 63352288 |
Spinal fracture | 15.48 | 9.68 | 9 | 129484 | 18262 | 63341267 |
Encephalopathy | 15.45 | 9.68 | 133 | 129360 | 38487 | 63321042 |
Ballismus | 15.45 | 9.68 | 7 | 129486 | 138 | 63359391 |
Facet joint syndrome | 15.43 | 9.68 | 3 | 129490 | 12135 | 63347394 |
Haematuria | 15.33 | 9.68 | 107 | 129386 | 29050 | 63330479 |
Haemorrhagic vasculitis | 15.30 | 9.68 | 6 | 129487 | 81 | 63359448 |
Paranasal sinus discomfort | 15.30 | 9.68 | 30 | 129463 | 4346 | 63355183 |
Toxic neuropathy | 15.26 | 9.68 | 10 | 129483 | 418 | 63359111 |
Hepatic cytolysis | 15.16 | 9.68 | 67 | 129426 | 15340 | 63344189 |
Tongue geographic | 15.11 | 9.68 | 6 | 129487 | 84 | 63359445 |
Nephropathy toxic | 14.99 | 9.68 | 48 | 129445 | 9431 | 63350098 |
Haemolytic anaemia | 14.87 | 9.68 | 50 | 129443 | 10075 | 63349454 |
Device malfunction | 14.84 | 9.68 | 9 | 129484 | 17848 | 63341681 |
Colonic abscess | 14.82 | 9.68 | 14 | 129479 | 1002 | 63358527 |
Hypercholesterolaemia | 14.81 | 9.68 | 13 | 129480 | 21321 | 63338208 |
Carbohydrate antigen 15-3 | 14.79 | 9.68 | 6 | 129487 | 89 | 63359440 |
Cerebrovascular accident | 14.68 | 9.68 | 145 | 129348 | 107879 | 63251650 |
Histamine intolerance | 14.66 | 9.68 | 5 | 129488 | 44 | 63359485 |
Vaginal infection | 14.66 | 9.68 | 41 | 129452 | 7477 | 63352052 |
Proctalgia | 14.65 | 9.68 | 36 | 129457 | 6074 | 63353455 |
Carcinoembryonic antigen | 14.61 | 9.68 | 6 | 129487 | 92 | 63359437 |
Deficiency of bile secretion | 14.59 | 9.68 | 4 | 129489 | 15 | 63359514 |
Plantar fasciitis | 14.58 | 9.68 | 27 | 129466 | 3748 | 63355781 |
Electrolyte imbalance | 14.53 | 9.68 | 80 | 129413 | 19996 | 63339533 |
Skin test positive | 14.50 | 9.68 | 12 | 129481 | 720 | 63358809 |
Dermatitis exfoliative generalised | 14.42 | 9.68 | 27 | 129466 | 3780 | 63355749 |
Poisoning | 14.34 | 9.68 | 5 | 129488 | 13695 | 63345834 |
Flushing | 14.28 | 9.68 | 92 | 129401 | 74995 | 63284534 |
Aortic rupture | 14.27 | 9.68 | 6 | 129487 | 98 | 63359431 |
Drug level below therapeutic | 14.23 | 9.68 | 31 | 129462 | 4835 | 63354694 |
Bone density decreased | 14.19 | 9.68 | 6 | 129487 | 14606 | 63344923 |
Walking disability | 14.18 | 9.68 | 16 | 129477 | 1411 | 63358118 |
Intentional self-injury | 14.12 | 9.68 | 19 | 129474 | 25668 | 63333861 |
Breast cancer female | 14.11 | 9.68 | 5 | 129488 | 13554 | 63345975 |
Vascular access site pain | 14.05 | 9.68 | 6 | 129487 | 102 | 63359427 |
Malignant melanoma | 14.03 | 9.68 | 3 | 129490 | 11353 | 63348176 |
Visual snow syndrome | 14.01 | 9.68 | 5 | 129488 | 51 | 63359478 |
Herpes simplex colitis | 14.01 | 9.68 | 4 | 129489 | 18 | 63359511 |
Tuberculosis gastrointestinal | 14.00 | 9.68 | 9 | 129484 | 364 | 63359165 |
Drug ineffective for unapproved indication | 13.99 | 9.68 | 118 | 129375 | 33945 | 63325584 |
Acid base balance abnormal | 13.99 | 9.68 | 8 | 129485 | 261 | 63359268 |
Depressed level of consciousness | 13.98 | 9.68 | 72 | 129421 | 62006 | 63297523 |
Lower respiratory tract infection | 13.93 | 9.68 | 188 | 129305 | 132119 | 63227410 |
Hyperpathia | 13.83 | 9.68 | 4 | 129489 | 19 | 63359510 |
Tremor | 13.69 | 9.68 | 360 | 129133 | 131879 | 63227650 |
Chronic fatigue syndrome | 13.69 | 9.68 | 14 | 129479 | 1104 | 63358425 |
Anal paraesthesia | 13.66 | 9.68 | 4 | 129489 | 20 | 63359509 |
Genital paraesthesia | 13.66 | 9.68 | 4 | 129489 | 20 | 63359509 |
Burning mouth syndrome | 13.66 | 9.68 | 10 | 129483 | 501 | 63359028 |
Enterobiasis | 13.59 | 9.68 | 5 | 129488 | 56 | 63359473 |
Visual impairment | 13.59 | 9.68 | 245 | 129248 | 84201 | 63275328 |
Foetal exposure during pregnancy | 13.53 | 9.68 | 28 | 129465 | 31934 | 63327595 |
Intentional product misuse | 13.53 | 9.68 | 71 | 129422 | 60846 | 63298683 |
Iatrogenic infection | 13.52 | 9.68 | 3 | 129490 | 3 | 63359526 |
Electrocardiogram QT prolonged | 13.51 | 9.68 | 183 | 129310 | 59347 | 63300182 |
Abdominal tenderness | 13.51 | 9.68 | 42 | 129451 | 8124 | 63351405 |
Hypoglossal nerve paresis | 13.49 | 9.68 | 6 | 129487 | 113 | 63359416 |
Clostridium colitis | 13.42 | 9.68 | 18 | 129475 | 1896 | 63357633 |
Iatrogenic injury | 13.37 | 9.68 | 12 | 129481 | 804 | 63358725 |
Portal fibrosis | 13.35 | 9.68 | 8 | 129485 | 285 | 63359244 |
Abdominal pain upper | 13.29 | 9.68 | 531 | 128962 | 205913 | 63153616 |
Joint range of motion decreased | 13.24 | 9.68 | 29 | 129464 | 32399 | 63327130 |
Pulmonary arterial hypertension | 13.14 | 9.68 | 16 | 129477 | 22561 | 63336968 |
Anorectal disorder | 13.11 | 9.68 | 17 | 129476 | 1732 | 63357797 |
Sensory disturbance | 13.11 | 9.68 | 59 | 129434 | 13613 | 63345916 |
Documented hypersensitivity to administered product | 13.08 | 9.68 | 10 | 129483 | 535 | 63358994 |
Ototoxicity | 13.07 | 9.68 | 15 | 129478 | 1347 | 63358182 |
Angiopathy | 13.05 | 9.68 | 29 | 129464 | 4584 | 63354945 |
Thrombotic thrombocytopenic purpura | 13.05 | 9.68 | 26 | 129467 | 3810 | 63355719 |
Neutropenic infection | 13.03 | 9.68 | 15 | 129478 | 1352 | 63358177 |
Increased bronchial secretion | 12.98 | 9.68 | 17 | 129476 | 1749 | 63357780 |
Pulmonary hypertension | 12.96 | 9.68 | 36 | 129457 | 37087 | 63322442 |
Cardiovascular disorder | 12.88 | 9.68 | 53 | 129440 | 11759 | 63347770 |
Self-injurious ideation | 12.85 | 9.68 | 21 | 129472 | 2638 | 63356891 |
Muscle rupture | 12.78 | 9.68 | 20 | 129473 | 2423 | 63357106 |
Metastases to kidney | 12.71 | 9.68 | 7 | 129486 | 212 | 63359317 |
Diarrhoea haemorrhagic | 12.71 | 9.68 | 44 | 129449 | 8998 | 63350531 |
Ligament disorder | 12.65 | 9.68 | 9 | 129484 | 431 | 63359098 |
Cholestasis | 12.64 | 9.68 | 103 | 129390 | 29331 | 63330198 |
Osteonecrosis | 12.64 | 9.68 | 19 | 129474 | 24511 | 63335018 |
Fear of death | 12.62 | 9.68 | 13 | 129480 | 1034 | 63358495 |
Myelosuppression | 12.57 | 9.68 | 18 | 129475 | 23685 | 63335844 |
Refractory anaemia with an excess of blasts | 12.52 | 9.68 | 9 | 129484 | 438 | 63359091 |
Fasciitis | 12.50 | 9.68 | 10 | 129483 | 572 | 63358957 |
Bacteraemia | 12.47 | 9.68 | 69 | 129424 | 17279 | 63342250 |
Peripheral nerve injury | 12.45 | 9.68 | 9 | 129484 | 442 | 63359087 |
Drug level decreased | 12.43 | 9.68 | 40 | 129453 | 7879 | 63351650 |
Vulvovaginal pain | 12.42 | 9.68 | 21 | 129472 | 2714 | 63356815 |
Blood creatine increased | 12.39 | 9.68 | 32 | 129461 | 5569 | 63353960 |
Deafness bilateral | 12.38 | 9.68 | 15 | 129478 | 1427 | 63358102 |
Vaginal abscess | 12.38 | 9.68 | 9 | 129484 | 446 | 63359083 |
Leukopenia | 12.36 | 9.68 | 224 | 129269 | 77066 | 63282463 |
Systemic inflammatory response syndrome | 12.31 | 9.68 | 32 | 129461 | 5589 | 63353940 |
Somatic dysfunction | 12.31 | 9.68 | 3 | 129490 | 6 | 63359523 |
Norovirus test positive | 12.28 | 9.68 | 7 | 129486 | 227 | 63359302 |
Productive cough | 12.24 | 9.68 | 189 | 129304 | 63019 | 63296510 |
Toxic leukoencephalopathy | 12.22 | 9.68 | 11 | 129482 | 740 | 63358789 |
Immunodeficiency | 12.16 | 9.68 | 14 | 129479 | 20240 | 63339289 |
Large intestinal obstruction | 12.15 | 9.68 | 19 | 129474 | 2300 | 63357229 |
Transmission of an infectious agent via product | 12.13 | 9.68 | 6 | 129487 | 145 | 63359384 |
Gastric disorder | 12.09 | 9.68 | 123 | 129370 | 37246 | 63322283 |
Acute myocardial infarction | 12.09 | 9.68 | 30 | 129463 | 32094 | 63327435 |
Liver function test increased | 12.07 | 9.68 | 31 | 129462 | 32780 | 63326749 |
Mitochondrial enzyme deficiency | 12.07 | 9.68 | 4 | 129489 | 32 | 63359497 |
Gastrointestinal infection | 12.04 | 9.68 | 44 | 129449 | 9237 | 63350292 |
Adjustment disorder with depressed mood | 12.00 | 9.68 | 3 | 129490 | 10201 | 63349328 |
Chronic sinusitis | 12.00 | 9.68 | 55 | 129438 | 12788 | 63346741 |
Diarrhoea infectious | 11.98 | 9.68 | 13 | 129480 | 1098 | 63358431 |
Tubulointerstitial nephritis and uveitis syndrome | 11.98 | 9.68 | 7 | 129486 | 238 | 63359291 |
Hearing disability | 11.96 | 9.68 | 4 | 129489 | 33 | 63359496 |
Hepatic cirrhosis | 11.95 | 9.68 | 20 | 129473 | 24714 | 63334815 |
Peritoneal adhesions | 11.93 | 9.68 | 7 | 129486 | 240 | 63359289 |
Pyuria | 11.92 | 9.68 | 17 | 129476 | 1897 | 63357632 |
Calculus bladder | 11.85 | 9.68 | 10 | 129483 | 617 | 63358912 |
Neurotoxicity | 11.83 | 9.68 | 67 | 129426 | 16923 | 63342606 |
Thyroxine increased | 11.82 | 9.68 | 10 | 129483 | 619 | 63358910 |
Exfoliative rash | 11.80 | 9.68 | 21 | 129472 | 2826 | 63356703 |
Conjunctival hyperaemia | 11.79 | 9.68 | 19 | 129474 | 2360 | 63357169 |
Urethral pain | 11.74 | 9.68 | 8 | 129485 | 357 | 63359172 |
Renal impairment | 11.74 | 9.68 | 249 | 129244 | 88106 | 63271423 |
Dehydration | 11.65 | 9.68 | 448 | 129045 | 172906 | 63186623 |
Endocarditis bacterial | 11.64 | 9.68 | 10 | 129483 | 632 | 63358897 |
Drug dependence | 11.64 | 9.68 | 20 | 129473 | 24463 | 63335066 |
Pleural neoplasm | 11.62 | 9.68 | 8 | 129485 | 363 | 63359166 |
Myosclerosis | 11.59 | 9.68 | 6 | 129487 | 160 | 63359369 |
Blood glucose increased | 11.56 | 9.68 | 112 | 129381 | 83644 | 63275885 |
Eye swelling | 11.55 | 9.68 | 86 | 129407 | 23832 | 63335697 |
Wrong technique in product usage process | 11.54 | 9.68 | 77 | 129416 | 62263 | 63297266 |
Food allergy | 11.53 | 9.68 | 50 | 129443 | 11351 | 63348178 |
Neoplasm progression | 11.51 | 9.68 | 37 | 129456 | 36391 | 63323138 |
Inappropriate antidiuretic hormone secretion | 11.45 | 9.68 | 62 | 129431 | 15400 | 63344129 |
Allodynia | 11.40 | 9.68 | 11 | 129482 | 808 | 63358721 |
Dysaesthesia | 11.40 | 9.68 | 27 | 129466 | 4451 | 63355078 |
Human ehrlichiosis | 11.39 | 9.68 | 6 | 129487 | 166 | 63359363 |
Erythema multiforme | 11.38 | 9.68 | 46 | 129447 | 10123 | 63349406 |
Hypertensive heart disease | 11.36 | 9.68 | 19 | 129474 | 2433 | 63357096 |
Episcleritis | 11.31 | 9.68 | 12 | 129481 | 988 | 63358541 |
Idiosyncratic drug reaction | 11.30 | 9.68 | 11 | 129482 | 817 | 63358712 |
Injection site rash | 11.30 | 9.68 | 13 | 129480 | 18796 | 63340733 |
Coeliac disease | 11.28 | 9.68 | 6 | 129487 | 12791 | 63346738 |
Peripheral venous disease | 11.28 | 9.68 | 9 | 129484 | 15468 | 63344061 |
Skin plaque | 11.27 | 9.68 | 40 | 129453 | 8280 | 63351249 |
Fracture | 11.27 | 9.68 | 14 | 129479 | 19570 | 63339959 |
Anal skin tags | 11.26 | 9.68 | 9 | 129484 | 514 | 63359015 |
Myositis | 11.25 | 9.68 | 43 | 129450 | 9223 | 63350306 |
Mucous stools | 11.24 | 9.68 | 26 | 129467 | 4222 | 63355307 |
Mineral metabolism disorder | 11.21 | 9.68 | 3 | 129490 | 10 | 63359519 |
Levator syndrome | 11.21 | 9.68 | 3 | 129490 | 10 | 63359519 |
Quadriparesis | 11.16 | 9.68 | 17 | 129476 | 2012 | 63357517 |
Sense of oppression | 11.15 | 9.68 | 12 | 129481 | 1004 | 63358525 |
Respiratory gas exchange disorder | 11.12 | 9.68 | 8 | 129485 | 390 | 63359139 |
Injection site thrombosis | 11.06 | 9.68 | 5 | 129488 | 98 | 63359431 |
Toxic encephalopathy | 11.03 | 9.68 | 34 | 129459 | 6545 | 63352984 |
Choriocarcinoma | 11.02 | 9.68 | 4 | 129489 | 43 | 63359486 |
Lupus-like syndrome | 11.01 | 9.68 | 9 | 129484 | 15286 | 63344243 |
Aural polyp | 10.97 | 9.68 | 5 | 129488 | 100 | 63359429 |
Acute psychosis | 10.95 | 9.68 | 19 | 129474 | 2506 | 63357023 |
Gallbladder injury | 10.93 | 9.68 | 14 | 129479 | 1409 | 63358120 |
Underdose | 10.84 | 9.68 | 25 | 129468 | 27431 | 63332098 |
Transient ischaemic attack | 10.81 | 9.68 | 40 | 129453 | 37713 | 63321816 |
Plasmapheresis | 10.80 | 9.68 | 7 | 129486 | 287 | 63359242 |
Noninfective gingivitis | 10.79 | 9.68 | 14 | 129479 | 1427 | 63358102 |
Increased tendency to bruise | 10.79 | 9.68 | 4 | 129489 | 10548 | 63348981 |
Cranial nerve disorder | 10.79 | 9.68 | 9 | 129484 | 546 | 63358983 |
Skin burning sensation | 10.78 | 9.68 | 53 | 129440 | 12681 | 63346848 |
Corynebacterium infection | 10.74 | 9.68 | 9 | 129484 | 550 | 63358979 |
Hyperinsulinaemia | 10.66 | 9.68 | 5 | 129488 | 107 | 63359422 |
Tachypnoea | 10.61 | 9.68 | 66 | 129427 | 17236 | 63342293 |
Dysphagia | 10.61 | 9.68 | 246 | 129247 | 88339 | 63271190 |
Hypoperfusion | 10.60 | 9.68 | 14 | 129479 | 1453 | 63358076 |
Leuconostoc infection | 10.60 | 9.68 | 3 | 129490 | 13 | 63359516 |
Biopsy colon abnormal | 10.57 | 9.68 | 5 | 129488 | 109 | 63359420 |
Hypoaesthesia | 10.57 | 9.68 | 432 | 129061 | 167961 | 63191568 |
Forced vital capacity decreased | 10.55 | 9.68 | 12 | 129481 | 1067 | 63358462 |
Injection site urticaria | 10.49 | 9.68 | 8 | 129485 | 14065 | 63345464 |
Graft versus host disease | 10.47 | 9.68 | 34 | 129459 | 6729 | 63352800 |
Lower limb fracture | 10.44 | 9.68 | 21 | 129472 | 24200 | 63335329 |
Clostridium bacteraemia | 10.37 | 9.68 | 6 | 129487 | 200 | 63359329 |
Bacterial endophthalmitis | 10.33 | 9.68 | 5 | 129488 | 115 | 63359414 |
Meniscus injury | 10.33 | 9.68 | 35 | 129458 | 7079 | 63352450 |
Post viral fatigue syndrome | 10.32 | 9.68 | 7 | 129486 | 310 | 63359219 |
Foreign body aspiration | 10.32 | 9.68 | 6 | 129487 | 202 | 63359327 |
Jaundice | 10.30 | 9.68 | 98 | 129395 | 29153 | 63330376 |
Hepatocellular injury | 10.28 | 9.68 | 93 | 129400 | 27288 | 63332241 |
Pneumonia mycoplasmal | 10.28 | 9.68 | 11 | 129482 | 914 | 63358615 |
Bovine tuberculosis | 10.27 | 9.68 | 4 | 129489 | 53 | 63359476 |
Right ventricular failure | 10.19 | 9.68 | 12 | 129481 | 17176 | 63342353 |
Therapeutic response unexpected | 10.19 | 9.68 | 14 | 129479 | 18745 | 63340784 |
Vulvovaginal candidiasis | 10.18 | 9.68 | 21 | 129472 | 3154 | 63356375 |
Mesenteritis | 10.18 | 9.68 | 7 | 129486 | 317 | 63359212 |
Staphylococcal sepsis | 10.10 | 9.68 | 38 | 129455 | 8090 | 63351439 |
Papule | 10.10 | 9.68 | 30 | 129463 | 5661 | 63353868 |
Injection site mass | 10.06 | 9.68 | 14 | 129479 | 18642 | 63340887 |
Urinary tract infection bacterial | 10.05 | 9.68 | 28 | 129465 | 5094 | 63354435 |
Small fibre neuropathy | 10.04 | 9.68 | 8 | 129485 | 455 | 63359074 |
Granulomatous liver disease | 10.00 | 9.68 | 10 | 129483 | 768 | 63358761 |
Folate deficiency | 9.93 | 9.68 | 18 | 129475 | 2457 | 63357072 |
Paraneoplastic syndrome | 9.89 | 9.68 | 9 | 129484 | 614 | 63358915 |
Stroke in evolution | 9.88 | 9.68 | 4 | 129489 | 59 | 63359470 |
C-reactive protein decreased | 9.88 | 9.68 | 11 | 129482 | 956 | 63358573 |
Gastrointestinal sounds abnormal | 9.86 | 9.68 | 24 | 129469 | 4027 | 63355502 |
Lower respiratory tract infection bacterial | 9.84 | 9.68 | 8 | 129485 | 468 | 63359061 |
Skin warm | 9.84 | 9.68 | 29 | 129464 | 5447 | 63354082 |
Purpura fulminans | 9.82 | 9.68 | 4 | 129489 | 60 | 63359469 |
Urine odour abnormal | 9.78 | 9.68 | 32 | 129461 | 6357 | 63353172 |
Mitochondrial toxicity | 9.77 | 9.68 | 8 | 129485 | 473 | 63359056 |
Drug withdrawal syndrome | 9.77 | 9.68 | 26 | 129467 | 27168 | 63332361 |
Porphyria acute | 9.71 | 9.68 | 12 | 129481 | 1165 | 63358364 |
Epilepsy | 9.69 | 9.68 | 91 | 129402 | 26974 | 63332555 |
Thrombocytosis | 9.69 | 9.68 | 30 | 129463 | 5788 | 63353741 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Tendon pain | 711.36 | 10.52 | 278 | 94988 | 2717 | 34858948 |
Tendonitis | 568.87 | 10.52 | 338 | 94928 | 8802 | 34852863 |
Tendon rupture | 456.53 | 10.52 | 267 | 94999 | 6745 | 34854920 |
Tendon disorder | 254.38 | 10.52 | 134 | 95132 | 2741 | 34858924 |
Pathogen resistance | 235.27 | 10.52 | 200 | 95066 | 9282 | 34852383 |
Death | 226.21 | 10.52 | 467 | 94799 | 397582 | 34464083 |
Toxic epidermal necrolysis | 210.66 | 10.52 | 277 | 94989 | 21369 | 34840296 |
Tendon discomfort | 188.18 | 10.52 | 56 | 95210 | 210 | 34861455 |
Drug hypersensitivity | 167.12 | 10.52 | 541 | 94725 | 79988 | 34781677 |
Drug abuse | 155.87 | 10.52 | 39 | 95227 | 99057 | 34762608 |
Completed suicide | 153.71 | 10.52 | 39 | 95227 | 98129 | 34763536 |
Drug reaction with eosinophilia and systemic symptoms | 150.30 | 10.52 | 299 | 94967 | 32713 | 34828952 |
Drug interaction | 128.75 | 10.52 | 1053 | 94213 | 224893 | 34636772 |
Myocardial infarction | 123.36 | 10.52 | 90 | 95176 | 120995 | 34740670 |
Joint noise | 110.21 | 10.52 | 48 | 95218 | 630 | 34861035 |
Clostridium difficile colitis | 108.54 | 10.52 | 171 | 95095 | 15559 | 34846106 |
Choroiditis | 108.53 | 10.52 | 57 | 95209 | 1158 | 34860507 |
Myalgia | 104.32 | 10.52 | 480 | 94786 | 83630 | 34778035 |
Night sweats | 102.68 | 10.52 | 176 | 95090 | 17176 | 34844489 |
Tubulointerstitial nephritis | 98.79 | 10.52 | 193 | 95073 | 20831 | 34840834 |
Drug resistance | 98.38 | 10.52 | 218 | 95048 | 25709 | 34835956 |
Eye pain | 84.23 | 10.52 | 140 | 95126 | 13322 | 34848343 |
Tinnitus | 81.85 | 10.52 | 174 | 95092 | 19944 | 34841721 |
Product dose omission issue | 80.58 | 10.52 | 126 | 95140 | 119585 | 34742080 |
Toxicity to various agents | 74.15 | 10.52 | 288 | 94978 | 200074 | 34661591 |
Paraesthesia | 72.82 | 10.52 | 357 | 94909 | 63815 | 34797850 |
Intentional overdose | 70.97 | 10.52 | 16 | 95250 | 43658 | 34818007 |
Solar lentigo | 70.59 | 10.52 | 33 | 95233 | 516 | 34861149 |
Hyperacusis | 69.39 | 10.52 | 38 | 95228 | 842 | 34860823 |
Dysplastic naevus | 67.47 | 10.52 | 31 | 95235 | 465 | 34861200 |
Anal fissure | 66.99 | 10.52 | 70 | 95196 | 4220 | 34857445 |
Cerebrovascular accident | 66.37 | 10.52 | 80 | 95186 | 84731 | 34776934 |
Septic shock | 66.00 | 10.52 | 377 | 94889 | 71457 | 34790208 |
Panic attack | 65.71 | 10.52 | 103 | 95163 | 9329 | 34852336 |
Arthralgia | 65.53 | 10.52 | 730 | 94536 | 169311 | 34692354 |
Photodermatosis | 63.72 | 10.52 | 31 | 95235 | 532 | 34861133 |
Fistula | 62.64 | 10.52 | 85 | 95181 | 6755 | 34854910 |
Torsade de pointes | 62.13 | 10.52 | 87 | 95179 | 7122 | 34854543 |
Fall | 62.12 | 10.52 | 313 | 94953 | 202572 | 34659093 |
Intraocular pressure increased | 60.44 | 10.52 | 74 | 95192 | 5309 | 34856356 |
Overdose | 60.16 | 10.52 | 97 | 95169 | 90962 | 34770703 |
Muscle rupture | 60.14 | 10.52 | 50 | 95216 | 2248 | 34859417 |
Stevens-Johnson syndrome | 56.89 | 10.52 | 144 | 95122 | 18495 | 34843170 |
Henoch-Schonlein purpura | 56.08 | 10.52 | 42 | 95224 | 1620 | 34860045 |
Hyperfibrinolysis | 55.34 | 10.52 | 13 | 95253 | 12 | 34861653 |
Rash morbilliform | 54.82 | 10.52 | 54 | 95212 | 3033 | 34858632 |
Spinal muscular atrophy | 54.65 | 10.52 | 25 | 95241 | 371 | 34861294 |
Dysbiosis | 53.80 | 10.52 | 27 | 95239 | 497 | 34861168 |
Muscle twitching | 52.64 | 10.52 | 98 | 95168 | 10200 | 34851465 |
Trichoglossia | 52.59 | 10.52 | 23 | 95243 | 305 | 34861360 |
Pseudomembranous colitis | 51.77 | 10.52 | 50 | 95216 | 2741 | 34858924 |
Pyrexia | 51.44 | 10.52 | 1228 | 94038 | 331785 | 34529880 |
Wrong technique in product usage process | 51.31 | 10.52 | 17 | 95249 | 35969 | 34825696 |
Cardiac failure congestive | 51.07 | 10.52 | 93 | 95173 | 83177 | 34778488 |
Rash maculo-papular | 50.04 | 10.52 | 181 | 95085 | 28270 | 34833395 |
Abdominal abscess | 49.50 | 10.52 | 59 | 95207 | 4116 | 34857549 |
Tracheobronchomegaly | 49.21 | 10.52 | 12 | 95254 | 15 | 34861650 |
Neuralgia | 48.48 | 10.52 | 119 | 95147 | 14994 | 34846671 |
Ligament pain | 48.33 | 10.52 | 13 | 95253 | 30 | 34861635 |
Clostridium difficile infection | 46.63 | 10.52 | 135 | 95131 | 18763 | 34842902 |
Ependymoma | 45.91 | 10.52 | 11 | 95255 | 12 | 34861653 |
Motor neurone disease | 45.46 | 10.52 | 24 | 95242 | 493 | 34861172 |
Cutaneous vasculitis | 45.29 | 10.52 | 57 | 95209 | 4206 | 34857459 |
Colitis | 44.23 | 10.52 | 212 | 95054 | 37538 | 34824127 |
Candida infection | 43.18 | 10.52 | 126 | 95140 | 17589 | 34844076 |
Sputum increased | 43.10 | 10.52 | 42 | 95224 | 2328 | 34859337 |
Foetal cardiac arrest | 42.65 | 10.52 | 11 | 95255 | 20 | 34861645 |
Foetal exposure during pregnancy | 41.86 | 10.52 | 26 | 95240 | 38075 | 34823590 |
Vanishing bile duct syndrome | 41.84 | 10.52 | 29 | 95237 | 989 | 34860676 |
Pseudomonas infection | 41.32 | 10.52 | 99 | 95167 | 12283 | 34849382 |
Suicide attempt | 39.88 | 10.52 | 29 | 95237 | 39087 | 34822578 |
Muscle atrophy | 39.78 | 10.52 | 72 | 95194 | 7332 | 34854333 |
Skin injury | 39.76 | 10.52 | 40 | 95226 | 2305 | 34859360 |
Injection site pain | 39.66 | 10.52 | 29 | 95237 | 38976 | 34822689 |
Condition aggravated | 39.41 | 10.52 | 739 | 94527 | 191457 | 34670208 |
Photosensitivity reaction | 38.97 | 10.52 | 88 | 95178 | 10506 | 34851159 |
Factor V inhibition | 38.85 | 10.52 | 16 | 95250 | 181 | 34861484 |
Pneumococcal sepsis | 36.74 | 10.52 | 28 | 95238 | 1109 | 34860556 |
Stoma closure | 36.58 | 10.52 | 17 | 95249 | 262 | 34861403 |
COVID-19 | 36.58 | 10.52 | 100 | 95166 | 77450 | 34784215 |
Fixed eruption | 36.43 | 10.52 | 33 | 95233 | 1667 | 34859998 |
Cardiac failure | 36.41 | 10.52 | 127 | 95139 | 91121 | 34770544 |
Inflammation | 36.16 | 10.52 | 163 | 95103 | 28132 | 34833533 |
Cross sensitivity reaction | 35.74 | 10.52 | 30 | 95236 | 1367 | 34860298 |
Linear IgA disease | 35.70 | 10.52 | 32 | 95234 | 1594 | 34860071 |
Acute myocardial infarction | 35.67 | 10.52 | 57 | 95209 | 53662 | 34808003 |
Impaired work ability | 35.48 | 10.52 | 66 | 95200 | 6864 | 34854801 |
Acute generalised exanthematous pustulosis | 35.28 | 10.52 | 65 | 95201 | 6711 | 34854954 |
Eosinophilia | 34.97 | 10.52 | 153 | 95113 | 26069 | 34835596 |
Malignant neoplasm progression | 34.83 | 10.52 | 123 | 95143 | 87923 | 34773742 |
Visual acuity reduced | 34.80 | 10.52 | 110 | 95156 | 16039 | 34845626 |
Tendon injury | 34.76 | 10.52 | 25 | 95241 | 905 | 34860760 |
Hyphaema | 34.67 | 10.52 | 21 | 95245 | 566 | 34861099 |
Blood glucose increased | 34.58 | 10.52 | 82 | 95184 | 66636 | 34795029 |
Ischaemic cerebral infarction | 34.45 | 10.52 | 28 | 95238 | 1219 | 34860446 |
Acute kidney injury | 34.07 | 10.52 | 1079 | 94187 | 303909 | 34557756 |
Aortic valve prolapse | 33.26 | 10.52 | 8 | 95258 | 9 | 34861656 |
Musculoskeletal injury | 33.16 | 10.52 | 13 | 95253 | 128 | 34861537 |
Anal abscess | 32.33 | 10.52 | 61 | 95205 | 6412 | 34855253 |
Pelvic abscess | 32.28 | 10.52 | 24 | 95242 | 915 | 34860750 |
Pancreatic enzyme abnormality | 32.22 | 10.52 | 11 | 95255 | 70 | 34861595 |
Dyspnoea | 32.15 | 10.52 | 782 | 94484 | 376000 | 34485665 |
Escherichia infection | 32.03 | 10.52 | 70 | 95196 | 8175 | 34853490 |
Yellow fever | 31.87 | 10.52 | 7 | 95259 | 3 | 34861662 |
Metabolic disorder | 31.55 | 10.52 | 48 | 95218 | 4235 | 34857430 |
Burning sensation | 31.48 | 10.52 | 116 | 95150 | 18278 | 34843387 |
Anal fistula | 30.93 | 10.52 | 54 | 95212 | 5345 | 34856320 |
Coronary artery disease | 30.46 | 10.52 | 53 | 95213 | 48252 | 34813413 |
Hepatitis cholestatic | 30.33 | 10.52 | 67 | 95199 | 7880 | 34853785 |
Prostatitis | 30.16 | 10.52 | 54 | 95212 | 5453 | 34856212 |
Increased bronchial secretion | 29.92 | 10.52 | 31 | 95235 | 1850 | 34859815 |
Clostridium test positive | 29.80 | 10.52 | 41 | 95225 | 3301 | 34858364 |
Lower respiratory tract infection bacterial | 29.79 | 10.52 | 18 | 95248 | 483 | 34861182 |
Diastasis recti abdominis | 29.59 | 10.52 | 9 | 95257 | 37 | 34861628 |
Undersensing | 29.52 | 10.52 | 7 | 95259 | 7 | 34861658 |
Uveitis | 29.30 | 10.52 | 64 | 95202 | 7471 | 34854194 |
Lymphadenectomy | 28.57 | 10.52 | 16 | 95250 | 371 | 34861294 |
Pain in extremity | 28.56 | 10.52 | 494 | 94772 | 126019 | 34735646 |
Sphingomonas paucimobilis infection | 28.50 | 10.52 | 9 | 95257 | 43 | 34861622 |
Anuria | 28.38 | 10.52 | 77 | 95189 | 10308 | 34851357 |
Urosepsis | 28.33 | 10.52 | 88 | 95178 | 12711 | 34848954 |
Pyelonephritis fungal | 28.24 | 10.52 | 10 | 95256 | 72 | 34861593 |
Penis injury | 28.03 | 10.52 | 14 | 95252 | 255 | 34861410 |
Aspergillus infection | 27.82 | 10.52 | 85 | 95181 | 12169 | 34849496 |
Abscess | 27.80 | 10.52 | 83 | 95183 | 11734 | 34849931 |
Bradycardia | 27.45 | 10.52 | 109 | 95157 | 75309 | 34786356 |
Connective tissue disorder | 27.15 | 10.52 | 13 | 95253 | 215 | 34861450 |
Hypoaesthesia | 26.98 | 10.52 | 271 | 94995 | 61173 | 34800492 |
Psoriasis | 26.90 | 10.52 | 40 | 95226 | 38772 | 34822893 |
Chest pain | 26.72 | 10.52 | 219 | 95047 | 126543 | 34735122 |
Infective pulmonary exacerbation of cystic fibrosis | 26.71 | 10.52 | 58 | 95208 | 6743 | 34854922 |
Infective aneurysm | 26.68 | 10.52 | 18 | 95248 | 587 | 34861078 |
Disease complication | 26.58 | 10.52 | 35 | 95231 | 2701 | 34858964 |
Chronic fatigue syndrome | 26.47 | 10.52 | 15 | 95251 | 356 | 34861309 |
Angina pectoris | 26.24 | 10.52 | 28 | 95238 | 31335 | 34830330 |
Intentional product misuse | 26.15 | 10.52 | 53 | 95213 | 45558 | 34816107 |
Renal tubular necrosis | 26.09 | 10.52 | 98 | 95168 | 15582 | 34846083 |
Rectal abscess | 26.00 | 10.52 | 25 | 95241 | 1363 | 34860302 |
Crohn's disease | 25.94 | 10.52 | 37 | 95229 | 3080 | 34858585 |
Leukocytosis | 25.94 | 10.52 | 132 | 95134 | 23933 | 34837732 |
Abdominal pain | 25.64 | 10.52 | 605 | 94661 | 163013 | 34698652 |
Penile haemorrhage | 25.58 | 10.52 | 18 | 95248 | 629 | 34861036 |
Coma | 25.41 | 10.52 | 54 | 95212 | 45624 | 34816041 |
Stenotrophomonas infection | 25.31 | 10.52 | 30 | 95236 | 2080 | 34859585 |
Chronic gastrointestinal bleeding | 25.18 | 10.52 | 14 | 95252 | 320 | 34861345 |
Asthma | 24.94 | 10.52 | 49 | 95217 | 42607 | 34819058 |
Hospitalisation | 24.91 | 10.52 | 76 | 95190 | 56826 | 34804839 |
Diabetic ketoacidosis | 24.87 | 10.52 | 9 | 95257 | 18023 | 34843642 |
Bone cyst | 24.79 | 10.52 | 26 | 95240 | 1574 | 34860091 |
Vitreous floaters | 24.76 | 10.52 | 39 | 95227 | 3546 | 34858119 |
Yellow fever vaccine-associated viscerotropic disease | 24.54 | 10.52 | 5 | 95261 | 0 | 34861665 |
Sensory processing disorder | 24.54 | 10.52 | 5 | 95261 | 0 | 34861665 |
Enterococcal infection | 24.44 | 10.52 | 68 | 95198 | 9238 | 34852427 |
Radiation inflammation | 24.33 | 10.52 | 20 | 95246 | 885 | 34860780 |
Hypertension | 24.29 | 10.52 | 246 | 95020 | 136197 | 34725468 |
Anxiety | 24.17 | 10.52 | 393 | 94873 | 99035 | 34762630 |
Walking aid user | 24.15 | 10.52 | 28 | 95238 | 1896 | 34859769 |
Chronic obstructive pulmonary disease | 23.88 | 10.52 | 62 | 95204 | 48856 | 34812809 |
Somnolence | 23.86 | 10.52 | 191 | 95075 | 110925 | 34750740 |
Phlebitis infective | 23.76 | 10.52 | 10 | 95256 | 120 | 34861545 |
Hypnagogic hallucination | 23.55 | 10.52 | 8 | 95258 | 50 | 34861615 |
Rash erythematous | 23.51 | 10.52 | 132 | 95134 | 24845 | 34836820 |
Joint ankylosis | 23.39 | 10.52 | 25 | 95241 | 1547 | 34860118 |
Gluten sensitivity | 22.97 | 10.52 | 7 | 95259 | 29 | 34861636 |
Sopor | 22.88 | 10.52 | 3 | 95263 | 12133 | 34849532 |
Pruritus genital | 22.67 | 10.52 | 29 | 95237 | 2175 | 34859490 |
Pouchitis | 22.29 | 10.52 | 17 | 95249 | 674 | 34860991 |
Cystic fibrosis | 22.29 | 10.52 | 25 | 95241 | 1633 | 34860032 |
Geotrichum infection | 22.24 | 10.52 | 15 | 95251 | 489 | 34861176 |
Bronchial disorder | 22.10 | 10.52 | 23 | 95243 | 1380 | 34860285 |
Lumbosacral plexus injury | 21.97 | 10.52 | 6 | 95260 | 15 | 34861650 |
Auditory disorder | 21.71 | 10.52 | 12 | 95254 | 271 | 34861394 |
Nosocomial infection | 21.46 | 10.52 | 21 | 95245 | 1170 | 34860495 |
Corneal deposits | 21.42 | 10.52 | 11 | 95255 | 213 | 34861452 |
Chest injury | 21.41 | 10.52 | 24 | 95242 | 1567 | 34860098 |
Necrotising retinitis | 21.37 | 10.52 | 18 | 95248 | 824 | 34860841 |
Drug-induced liver injury | 21.23 | 10.52 | 143 | 95123 | 28689 | 34832976 |
Acinetobacter infection | 21.22 | 10.52 | 21 | 95245 | 1186 | 34860479 |
Urinary tract infection | 21.05 | 10.52 | 334 | 94932 | 83747 | 34777918 |
Painful respiration | 20.80 | 10.52 | 21 | 95245 | 1215 | 34860450 |
Premature baby | 20.74 | 10.52 | 14 | 95252 | 19619 | 34842046 |
Ischaemic stroke | 20.68 | 10.52 | 12 | 95254 | 18238 | 34843427 |
Cardio-respiratory arrest | 20.67 | 10.52 | 79 | 95187 | 55194 | 34806471 |
Disease progression | 20.43 | 10.52 | 192 | 95074 | 107885 | 34753780 |
Obesity | 20.36 | 10.52 | 5 | 95261 | 12873 | 34848792 |
Palpitations | 20.35 | 10.52 | 182 | 95084 | 39804 | 34821861 |
Visual impairment | 20.35 | 10.52 | 167 | 95099 | 35635 | 34826030 |
Pulmonary embolism | 20.32 | 10.52 | 152 | 95114 | 89594 | 34772071 |
Prostate cancer | 20.32 | 10.52 | 49 | 95217 | 39600 | 34822065 |
Deep vein thrombosis | 20.29 | 10.52 | 100 | 95166 | 65148 | 34796517 |
Metastases to liver | 20.29 | 10.52 | 6 | 95260 | 13657 | 34848008 |
Nasopharyngitis | 20.20 | 10.52 | 110 | 95156 | 69858 | 34791807 |
Anti-cyclic citrullinated peptide antibody positive | 20.15 | 10.52 | 25 | 95241 | 1818 | 34859847 |
Enterocutaneous fistula | 20.06 | 10.52 | 19 | 95247 | 1016 | 34860649 |
Platelet count decreased | 20.02 | 10.52 | 219 | 95047 | 119498 | 34742167 |
Food intolerance | 19.93 | 10.52 | 22 | 95244 | 1412 | 34860253 |
Hepatic encephalopathy | 19.82 | 10.52 | 86 | 95180 | 14599 | 34847066 |
Right ventricle outflow tract obstruction | 19.78 | 10.52 | 5 | 95261 | 8 | 34861657 |
Infusion related reaction | 19.74 | 10.52 | 76 | 95190 | 52981 | 34808684 |
Posterior tibial tendon dysfunction | 19.63 | 10.52 | 4 | 95262 | 0 | 34861665 |
Yellow fever vaccine-associated neurotropic disease | 19.63 | 10.52 | 4 | 95262 | 0 | 34861665 |
Product quality issue | 19.59 | 10.52 | 11 | 95255 | 17024 | 34844641 |
Vitamin K deficiency | 19.49 | 10.52 | 11 | 95255 | 259 | 34861406 |
Neuropathy peripheral | 19.45 | 10.52 | 327 | 94939 | 82936 | 34778729 |
COVID-19 pneumonia | 19.45 | 10.52 | 11 | 95255 | 16956 | 34844709 |
Cholestasis | 19.45 | 10.52 | 133 | 95133 | 26815 | 34834850 |
Cardiac disorder | 19.30 | 10.52 | 57 | 95209 | 43069 | 34818596 |
Organic brain syndrome | 19.26 | 10.52 | 11 | 95255 | 265 | 34861400 |
Faciobrachial dystonic seizure | 19.24 | 10.52 | 7 | 95259 | 55 | 34861610 |
Pulmonary pain | 19.16 | 10.52 | 20 | 95246 | 1204 | 34860461 |
Lip erosion | 19.11 | 10.52 | 15 | 95251 | 621 | 34861044 |
Abscess intestinal | 19.08 | 10.52 | 23 | 95243 | 1623 | 34860042 |
Orchitis | 19.05 | 10.52 | 23 | 95243 | 1626 | 34860039 |
Defaecation urgency | 19.05 | 10.52 | 29 | 95237 | 2560 | 34859105 |
Aeromonas infection | 18.97 | 10.52 | 11 | 95255 | 273 | 34861392 |
Megacolon | 18.91 | 10.52 | 24 | 95242 | 1786 | 34859879 |
Leukocyturia | 18.84 | 10.52 | 15 | 95251 | 634 | 34861031 |
Oxidative stress | 18.81 | 10.52 | 7 | 95259 | 59 | 34861606 |
Intentional self-injury | 18.78 | 10.52 | 7 | 95259 | 13764 | 34847901 |
Neuroleptic malignant syndrome | 18.67 | 10.52 | 13 | 95253 | 17921 | 34843744 |
Agranulocytosis | 18.66 | 10.52 | 120 | 95146 | 23701 | 34837964 |
Increased viscosity of bronchial secretion | 18.66 | 10.52 | 10 | 95256 | 212 | 34861453 |
Incorrect dose administered | 18.53 | 10.52 | 53 | 95213 | 40462 | 34821203 |
Treatment noncompliance | 18.48 | 10.52 | 30 | 95236 | 28070 | 34833595 |
Systemic candida | 18.47 | 10.52 | 35 | 95231 | 3691 | 34857974 |
Nail bed bleeding | 18.35 | 10.52 | 12 | 95254 | 371 | 34861294 |
Cerebral infarction | 18.35 | 10.52 | 29 | 95237 | 27426 | 34834239 |
Accidental exposure to product | 18.33 | 10.52 | 6 | 95260 | 12796 | 34848869 |
Product administration error | 18.16 | 10.52 | 11 | 95255 | 16333 | 34845332 |
Aortic aneurysm rupture | 18.11 | 10.52 | 18 | 95248 | 1022 | 34860643 |
Clostridial infection | 17.89 | 10.52 | 34 | 95232 | 3593 | 34858072 |
Nail bed inflammation | 17.77 | 10.52 | 9 | 95257 | 169 | 34861496 |
Muscle injury | 17.65 | 10.52 | 21 | 95245 | 1462 | 34860203 |
Respiratory tract infection bacterial | 17.63 | 10.52 | 23 | 95243 | 1759 | 34859906 |
Multiple organ dysfunction syndrome | 17.63 | 10.52 | 300 | 94966 | 76266 | 34785399 |
Anxiety disorder | 17.51 | 10.52 | 23 | 95243 | 1771 | 34859894 |
Plantar fasciitis | 17.44 | 10.52 | 25 | 95241 | 2091 | 34859574 |
Gastrointestinal inflammation | 17.43 | 10.52 | 33 | 95233 | 3478 | 34858187 |
Musculoskeletal discomfort | 17.42 | 10.52 | 55 | 95211 | 8013 | 34853652 |
Dyspnoea exertional | 17.41 | 10.52 | 60 | 95206 | 43219 | 34818446 |
Prolapse | 17.40 | 10.52 | 4 | 95262 | 3 | 34861662 |
Necrotising scleritis | 17.33 | 10.52 | 7 | 95259 | 75 | 34861590 |
Weight bearing difficulty | 17.33 | 10.52 | 18 | 95248 | 1077 | 34860588 |
Muscle tightness | 17.33 | 10.52 | 40 | 95226 | 4844 | 34856821 |
Trichosporon infection | 17.22 | 10.52 | 15 | 95251 | 719 | 34860946 |
Magnesium deficiency | 17.17 | 10.52 | 7 | 95259 | 77 | 34861588 |
Cystitis | 17.06 | 10.52 | 62 | 95204 | 9703 | 34851962 |
Haematospermia | 17.05 | 10.52 | 11 | 95255 | 332 | 34861333 |
Generalised oedema | 17.00 | 10.52 | 73 | 95193 | 12335 | 34849330 |
Hyperthyroidism | 16.90 | 10.52 | 4 | 95262 | 10562 | 34851103 |
Septic embolus | 16.88 | 10.52 | 19 | 95247 | 1246 | 34860419 |
Kounis syndrome | 16.85 | 10.52 | 27 | 95239 | 2491 | 34859174 |
Intestinal stenosis | 16.82 | 10.52 | 25 | 95241 | 2161 | 34859504 |
Intestinal fistula | 16.78 | 10.52 | 17 | 95249 | 988 | 34860677 |
Scleromalacia | 16.75 | 10.52 | 5 | 95261 | 19 | 34861646 |
Cholestatic liver injury | 16.72 | 10.52 | 26 | 95240 | 2338 | 34859327 |
Mucosal disorder | 16.64 | 10.52 | 22 | 95244 | 1704 | 34859961 |
Dermatitis bullous | 16.64 | 10.52 | 49 | 95217 | 6873 | 34854792 |
Nephritis allergic | 16.53 | 10.52 | 12 | 95254 | 441 | 34861224 |
Joint stiffness | 16.49 | 10.52 | 66 | 95200 | 10807 | 34850858 |
Hyperkalaemia | 16.44 | 10.52 | 116 | 95150 | 69273 | 34792392 |
Resuscitation | 16.35 | 10.52 | 20 | 95246 | 1433 | 34860232 |
Throat tightness | 16.27 | 10.52 | 55 | 95211 | 8303 | 34853362 |
Hypogonadism | 16.23 | 10.52 | 25 | 95241 | 2230 | 34859435 |
Muscle fatigue | 16.22 | 10.52 | 20 | 95246 | 1445 | 34860220 |
Lung consolidation | 16.21 | 10.52 | 44 | 95222 | 5892 | 34855773 |
Retinitis viral | 16.13 | 10.52 | 7 | 95259 | 91 | 34861574 |
Fat tissue decreased | 16.13 | 10.52 | 7 | 95259 | 91 | 34861574 |
Cough | 16.13 | 10.52 | 300 | 94966 | 149840 | 34711825 |
Necrotising fasciitis | 16.08 | 10.52 | 33 | 95233 | 3689 | 34857976 |
Epistaxis | 16.04 | 10.52 | 93 | 95173 | 58158 | 34803507 |
Escherichia urinary tract infection | 15.98 | 10.52 | 32 | 95234 | 3514 | 34858151 |
Procalcitonin decreased | 15.86 | 10.52 | 7 | 95259 | 95 | 34861570 |
Corneal opacity | 15.86 | 10.52 | 13 | 95253 | 573 | 34861092 |
Drug dependence | 15.79 | 10.52 | 26 | 95240 | 24191 | 34837474 |
Pharyngeal erythema | 15.71 | 10.52 | 14 | 95252 | 692 | 34860973 |
Urinary tract obstruction | 15.52 | 10.52 | 32 | 95234 | 3588 | 34858077 |
Catatonia | 15.51 | 10.52 | 39 | 95227 | 4986 | 34856679 |
Fluorosis | 15.50 | 10.52 | 6 | 95260 | 57 | 34861608 |
Hepatotoxicity | 15.48 | 10.52 | 106 | 95160 | 21379 | 34840286 |
Therapeutic product effect incomplete | 15.40 | 10.52 | 78 | 95188 | 50463 | 34811202 |
Perirectal abscess | 15.39 | 10.52 | 21 | 95245 | 1677 | 34859988 |
Angina bullosa haemorrhagica | 15.31 | 10.52 | 6 | 95260 | 59 | 34861606 |
Intestinal intraepithelial lymphocytes increased | 15.25 | 10.52 | 8 | 95258 | 162 | 34861503 |
Myocardial ischaemia | 15.18 | 10.52 | 15 | 95251 | 17393 | 34844272 |
Flushing | 15.13 | 10.52 | 42 | 95224 | 32378 | 34829287 |
Exposure during pregnancy | 15.07 | 10.52 | 3 | 95263 | 8931 | 34852734 |
Injection site haemorrhage | 15.04 | 10.52 | 4 | 95262 | 9764 | 34851901 |
Ligament injury | 14.99 | 10.52 | 10 | 95256 | 320 | 34861345 |
Influenza | 14.94 | 10.52 | 77 | 95189 | 49589 | 34812076 |
Oesophageal mucosa erythema | 14.89 | 10.52 | 5 | 95261 | 30 | 34861635 |
Cardiac arrest | 14.86 | 10.52 | 179 | 95087 | 95980 | 34765685 |
Scoliosis | 14.80 | 10.52 | 27 | 95239 | 2766 | 34858899 |
Actinic keratosis | 14.69 | 10.52 | 36 | 95230 | 4531 | 34857134 |
Abscess bacterial | 14.58 | 10.52 | 8 | 95258 | 178 | 34861487 |
Sensitisation | 14.50 | 10.52 | 8 | 95258 | 180 | 34861485 |
Nutritional condition abnormal | 14.47 | 10.52 | 11 | 95255 | 434 | 34861231 |
Gingival recession | 14.47 | 10.52 | 11 | 95255 | 434 | 34861231 |
Blood cholesterol increased | 14.40 | 10.52 | 21 | 95245 | 20522 | 34841143 |
Febrile neutropenia | 14.39 | 10.52 | 481 | 94785 | 136368 | 34725297 |
Withdrawal syndrome | 14.38 | 10.52 | 8 | 95258 | 12447 | 34849218 |
Blood creatine phosphokinase increased | 14.38 | 10.52 | 68 | 95198 | 44789 | 34816876 |
Salivary hypersecretion | 14.38 | 10.52 | 3 | 95263 | 8641 | 34853024 |
Skin burning sensation | 14.30 | 10.52 | 36 | 95230 | 4607 | 34857058 |
Necrosis | 14.23 | 10.52 | 41 | 95225 | 5682 | 34855983 |
Crystal nephropathy | 14.21 | 10.52 | 11 | 95255 | 446 | 34861219 |
Gynaecomastia | 14.18 | 10.52 | 5 | 95261 | 10175 | 34851490 |
Lymphocyte count decreased | 14.09 | 10.52 | 25 | 95241 | 22597 | 34839068 |
Glomerular filtration rate decreased | 14.02 | 10.52 | 9 | 95257 | 12952 | 34848713 |
Ejection fraction decreased | 14.00 | 10.52 | 19 | 95247 | 19135 | 34842530 |
Mucosal atrophy | 13.97 | 10.52 | 6 | 95260 | 76 | 34861589 |
Klebsiella infection | 13.93 | 10.52 | 53 | 95213 | 8478 | 34853187 |
Poisoning | 13.91 | 10.52 | 8 | 95258 | 12218 | 34849447 |
Roseolovirus test positive | 13.90 | 10.52 | 6 | 95260 | 77 | 34861588 |
Sitting disability | 13.89 | 10.52 | 8 | 95258 | 196 | 34861469 |
Thrombocytosis | 13.85 | 10.52 | 33 | 95233 | 4079 | 34857586 |
Haemorrhoids thrombosed | 13.82 | 10.52 | 8 | 95258 | 198 | 34861467 |
Otorrhoea | 13.80 | 10.52 | 12 | 95254 | 574 | 34861091 |
Hypotension | 13.79 | 10.52 | 480 | 94786 | 221169 | 34640496 |
Blood triglycerides increased | 13.79 | 10.52 | 11 | 95255 | 14148 | 34847517 |
Genital pain | 13.77 | 10.52 | 11 | 95255 | 467 | 34861198 |
Probiotic therapy | 13.75 | 10.52 | 7 | 95259 | 133 | 34861532 |
Eye infection fungal | 13.71 | 10.52 | 10 | 95256 | 370 | 34861295 |
Osteolysis | 13.70 | 10.52 | 28 | 95238 | 3120 | 34858545 |
Gastrooesophageal reflux disease | 13.67 | 10.52 | 55 | 95211 | 37869 | 34823796 |
Thrombosis | 13.66 | 10.52 | 81 | 95185 | 50377 | 34811288 |
Interstitial lung disease | 13.64 | 10.52 | 113 | 95153 | 65169 | 34796496 |
Blood pressure increased | 13.62 | 10.52 | 164 | 95102 | 87938 | 34773727 |
Skin wrinkling | 13.60 | 10.52 | 10 | 95256 | 375 | 34861290 |
Ligament disorder | 13.56 | 10.52 | 7 | 95259 | 137 | 34861528 |
Glycosylated haemoglobin increased | 13.56 | 10.52 | 7 | 95259 | 11353 | 34850312 |
Aortic aneurysm | 13.54 | 10.52 | 45 | 95221 | 6734 | 34854931 |
Thrombotic thrombocytopenic purpura | 13.53 | 10.52 | 29 | 95237 | 3341 | 34858324 |
Incision site discharge | 13.44 | 10.52 | 4 | 95262 | 15 | 34861650 |
Chest X-ray abnormal | 13.44 | 10.52 | 34 | 95232 | 4364 | 34857301 |
Toxic encephalopathy | 13.43 | 10.52 | 38 | 95228 | 5211 | 34856454 |
International normalised ratio increased | 13.39 | 10.52 | 192 | 95074 | 47135 | 34814530 |
Haemoglobin decreased | 13.38 | 10.52 | 240 | 95026 | 120532 | 34741133 |
Arteriosclerosis | 13.38 | 10.52 | 8 | 95258 | 11960 | 34849705 |
Mental fatigue | 13.34 | 10.52 | 7 | 95259 | 142 | 34861523 |
Epididymitis | 13.32 | 10.52 | 24 | 95242 | 2435 | 34859230 |
Gallbladder polyp | 13.30 | 10.52 | 10 | 95256 | 388 | 34861277 |
Subacute cutaneous lupus erythematosus | 13.28 | 10.52 | 15 | 95251 | 987 | 34860678 |
Subdural haematoma | 13.24 | 10.52 | 22 | 95244 | 20399 | 34841266 |
Erysipelas | 13.23 | 10.52 | 36 | 95230 | 4827 | 34856838 |
Pruritus | 13.18 | 10.52 | 492 | 94774 | 141489 | 34720176 |
Fluid retention | 13.18 | 10.52 | 34 | 95232 | 26853 | 34834812 |
Left ventricular hypertrophy | 13.16 | 10.52 | 3 | 95263 | 8127 | 34853538 |
Underdose | 13.05 | 10.52 | 11 | 95255 | 13769 | 34847896 |
Small fibre neuropathy | 13.00 | 10.52 | 6 | 95260 | 91 | 34861574 |
Hypophosphataemia | 12.85 | 10.52 | 7 | 95259 | 11019 | 34850646 |
Pseudopolyp | 12.84 | 10.52 | 8 | 95258 | 227 | 34861438 |
Constipation | 12.82 | 10.52 | 280 | 94986 | 136702 | 34724963 |
Cryptitis | 12.81 | 10.52 | 8 | 95258 | 228 | 34861437 |
Lactic acidosis | 12.81 | 10.52 | 50 | 95216 | 34722 | 34826943 |
Motor dysfunction | 12.80 | 10.52 | 45 | 95221 | 6929 | 34854736 |
Glare | 12.77 | 10.52 | 6 | 95260 | 95 | 34861570 |
Scrotal pain | 12.76 | 10.52 | 14 | 95252 | 892 | 34860773 |
Cervicobrachial syndrome | 12.75 | 10.52 | 9 | 95257 | 316 | 34861349 |
Faecal calprotectin increased | 12.74 | 10.52 | 24 | 95242 | 2520 | 34859145 |
Arterial angioplasty | 12.69 | 10.52 | 5 | 95261 | 50 | 34861615 |
Pulmonary arterial hypertension | 12.68 | 10.52 | 4 | 95262 | 8735 | 34852930 |
Cogwheel rigidity | 12.68 | 10.52 | 17 | 95249 | 1335 | 34860330 |
Toxic skin eruption | 12.65 | 10.52 | 63 | 95203 | 11322 | 34850343 |
Vertebral artery hypoplasia | 12.65 | 10.52 | 3 | 95263 | 3 | 34861662 |
Spinal meningeal cyst | 12.65 | 10.52 | 3 | 95263 | 3 | 34861662 |
Arthritis gonococcal | 12.65 | 10.52 | 3 | 95263 | 3 | 34861662 |
Hepatic cytolysis | 12.59 | 10.52 | 75 | 95191 | 14421 | 34847244 |
Pseudomonal sepsis | 12.53 | 10.52 | 29 | 95237 | 3518 | 34858147 |
Jaundice | 12.29 | 10.52 | 137 | 95129 | 31745 | 34829920 |
Atrioventricular block complete | 12.27 | 10.52 | 5 | 95261 | 9314 | 34852351 |
Pulmonary hypertension | 12.26 | 10.52 | 24 | 95242 | 20900 | 34840765 |
Urinary retention | 12.24 | 10.52 | 152 | 95114 | 36136 | 34825529 |
Peroneal nerve palsy | 12.19 | 10.52 | 26 | 95240 | 2985 | 34858680 |
Large intestinal stenosis | 12.17 | 10.52 | 18 | 95248 | 1549 | 34860116 |
Myoglobin urine present | 12.13 | 10.52 | 7 | 95259 | 172 | 34861493 |
Prescribed overdose | 12.07 | 10.52 | 7 | 95259 | 10640 | 34851025 |
General physical health deterioration | 12.06 | 10.52 | 262 | 95004 | 128007 | 34733658 |
Cardiogenic shock | 12.04 | 10.52 | 35 | 95231 | 26583 | 34835082 |
Aspartate aminotransferase | 12.03 | 10.52 | 6 | 95260 | 109 | 34861556 |
Hyperglycaemia | 11.99 | 10.52 | 61 | 95205 | 39419 | 34822246 |
Joint instability | 11.91 | 10.52 | 10 | 95256 | 456 | 34861209 |
Vertigo positional | 11.89 | 10.52 | 13 | 95253 | 825 | 34860840 |
Osteonecrosis of jaw | 11.85 | 10.52 | 19 | 95247 | 17870 | 34843795 |
Pruritus allergic | 11.80 | 10.52 | 8 | 95258 | 263 | 34861402 |
Muscle discomfort | 11.78 | 10.52 | 6 | 95260 | 114 | 34861551 |
Cerebral ischaemia | 11.78 | 10.52 | 41 | 95225 | 6281 | 34855384 |
White blood cell count decreased | 11.76 | 10.52 | 186 | 95080 | 95259 | 34766406 |
Idiosyncratic drug reaction | 11.72 | 10.52 | 10 | 95256 | 466 | 34861199 |
Fear of death | 11.70 | 10.52 | 11 | 95255 | 583 | 34861082 |
Pneumonia pseudomonal | 11.65 | 10.52 | 30 | 95236 | 3892 | 34857773 |
Mucosal hyperaemia | 11.64 | 10.52 | 4 | 95262 | 26 | 34861639 |
Prothrombin time shortened | 11.63 | 10.52 | 17 | 95249 | 1447 | 34860218 |
Incorrect route of product administration | 11.60 | 10.52 | 14 | 95252 | 14831 | 34846834 |
Device malfunction | 11.60 | 10.52 | 7 | 95259 | 10414 | 34851251 |
Hand deformity | 11.59 | 10.52 | 29 | 95237 | 3696 | 34857969 |
Dysuria | 11.55 | 10.52 | 119 | 95147 | 27033 | 34834632 |
Hepatic amoebiasis | 11.52 | 10.52 | 5 | 95261 | 65 | 34861600 |
Anal stenosis | 11.51 | 10.52 | 7 | 95259 | 190 | 34861475 |
Hypersensitivity vasculitis | 11.49 | 10.52 | 27 | 95239 | 3308 | 34858357 |
Depressed level of consciousness | 11.47 | 10.52 | 69 | 95197 | 42772 | 34818893 |
Pseudoporphyria | 11.45 | 10.52 | 9 | 95257 | 373 | 34861292 |
Renal abscess | 11.43 | 10.52 | 8 | 95258 | 277 | 34861388 |
Psoas abscess | 11.42 | 10.52 | 11 | 95255 | 601 | 34861064 |
Microvillous inclusion disease | 11.42 | 10.52 | 7 | 95259 | 193 | 34861472 |
Angina unstable | 11.41 | 10.52 | 9 | 95257 | 11644 | 34850021 |
Graft versus host disease | 11.41 | 10.52 | 58 | 95208 | 10511 | 34851154 |
Retinopathy hypertensive | 11.38 | 10.52 | 8 | 95258 | 279 | 34861386 |
Aggression | 11.38 | 10.52 | 61 | 95205 | 38903 | 34822762 |
Atelectasis | 11.34 | 10.52 | 85 | 95181 | 17642 | 34844023 |
Hyperinsulinaemia | 11.32 | 10.52 | 5 | 95261 | 68 | 34861597 |
Eye excision | 11.27 | 10.52 | 4 | 95262 | 29 | 34861636 |
Breast inflammation | 11.27 | 10.52 | 4 | 95262 | 29 | 34861636 |
Systemic inflammatory response syndrome | 11.22 | 10.52 | 42 | 95224 | 6667 | 34854998 |
Muscle contractions involuntary | 11.21 | 10.52 | 19 | 95247 | 1837 | 34859828 |
Hypofibrinogenaemia | 11.17 | 10.52 | 18 | 95248 | 1668 | 34859997 |
Hyperoxaluria | 11.16 | 10.52 | 6 | 95260 | 128 | 34861537 |
Stenotrophomonas test positive | 11.14 | 10.52 | 8 | 95258 | 289 | 34861376 |
Pudendal canal syndrome | 11.13 | 10.52 | 3 | 95263 | 7 | 34861658 |
Blood catecholamines decreased | 11.13 | 10.52 | 3 | 95263 | 7 | 34861658 |
Microbiology test abnormal | 11.13 | 10.52 | 3 | 95263 | 7 | 34861658 |
Neuropsychiatric symptoms | 11.11 | 10.52 | 13 | 95253 | 889 | 34860776 |
Right ventricular failure | 11.11 | 10.52 | 5 | 95261 | 8779 | 34852886 |
Loss of proprioception | 11.09 | 10.52 | 9 | 95257 | 391 | 34861274 |
Bacterial disease carrier | 11.06 | 10.52 | 10 | 95256 | 504 | 34861161 |
Presyncope | 11.05 | 10.52 | 22 | 95244 | 19037 | 34842628 |
Ligament rupture | 11.04 | 10.52 | 14 | 95252 | 1041 | 34860624 |
Lower gastrointestinal haemorrhage | 11.02 | 10.52 | 6 | 95260 | 9446 | 34852219 |
Bladder spasm | 11.00 | 10.52 | 13 | 95253 | 899 | 34860766 |
Wound drainage | 10.97 | 10.52 | 11 | 95255 | 631 | 34861034 |
Unmasking of previously unidentified disease | 10.97 | 10.52 | 13 | 95253 | 901 | 34860764 |
Cataract subcapsular | 10.97 | 10.52 | 9 | 95257 | 397 | 34861268 |
Osteoporosis | 10.95 | 10.52 | 11 | 95255 | 12657 | 34849008 |
Disseminated intravascular coagulation | 10.94 | 10.52 | 99 | 95167 | 21717 | 34839948 |
Purpura non-thrombocytopenic | 10.88 | 10.52 | 5 | 95261 | 75 | 34861590 |
Apoptosis | 10.88 | 10.52 | 9 | 95257 | 402 | 34861263 |
Walking disability | 10.87 | 10.52 | 13 | 95253 | 910 | 34860755 |
Rash | 10.85 | 10.52 | 725 | 94541 | 222027 | 34639638 |
Injection site bruising | 10.85 | 10.52 | 5 | 95261 | 8658 | 34853007 |
Hepatic infarction | 10.83 | 10.52 | 7 | 95259 | 212 | 34861453 |
Drain placement | 10.82 | 10.52 | 5 | 95261 | 76 | 34861589 |
Seizure | 10.79 | 10.52 | 211 | 95055 | 104646 | 34757019 |
Irritability | 10.78 | 10.52 | 33 | 95233 | 24657 | 34837008 |
Spontaneous haematoma | 10.76 | 10.52 | 10 | 95256 | 522 | 34861143 |
Abdominal wall abscess | 10.75 | 10.52 | 10 | 95256 | 523 | 34861142 |
Type 2 diabetes mellitus | 10.65 | 10.52 | 17 | 95249 | 16015 | 34845650 |
Jaundice cholestatic | 10.64 | 10.52 | 33 | 95233 | 4761 | 34856904 |
Glomerulonephritis acute | 10.64 | 10.52 | 6 | 95260 | 141 | 34861524 |
Dermatitis exfoliative | 10.64 | 10.52 | 41 | 95225 | 6598 | 34855067 |
Yawning | 10.60 | 10.52 | 10 | 95256 | 532 | 34861133 |
Sensory disturbance | 10.60 | 10.52 | 39 | 95227 | 6138 | 34855527 |
Hepato-lenticular degeneration | 10.59 | 10.52 | 3 | 95263 | 9 | 34861656 |
Contusion | 10.58 | 10.52 | 57 | 95209 | 36307 | 34825358 |
Herpes zoster meningoencephalitis | 10.54 | 10.52 | 8 | 95258 | 315 | 34861350 |
Flavobacterium infection | 10.54 | 10.52 | 5 | 95261 | 81 | 34861584 |
Staphylococcal infection | 10.53 | 10.52 | 136 | 95130 | 32624 | 34829041 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Tendon pain | 1159.11 | 9.48 | 458 | 194569 | 5200 | 79544161 |
Tendonitis | 855.70 | 9.48 | 599 | 194428 | 23231 | 79526130 |
Drug hypersensitivity | 771.49 | 9.48 | 2023 | 193004 | 296893 | 79252468 |
Tendon rupture | 546.29 | 9.48 | 351 | 194676 | 11775 | 79537586 |
Drug reaction with eosinophilia and systemic symptoms | 482.92 | 9.48 | 686 | 194341 | 63558 | 79485803 |
Pathogen resistance | 467.60 | 9.48 | 340 | 194687 | 14002 | 79535359 |
Tendon disorder | 439.45 | 9.48 | 253 | 194774 | 6933 | 79542428 |
Toxic epidermal necrolysis | 395.57 | 9.48 | 516 | 194511 | 44065 | 79505296 |
Drug interaction | 350.71 | 9.48 | 1966 | 193061 | 413217 | 79136144 |
Tubulointerstitial nephritis | 288.31 | 9.48 | 409 | 194618 | 37826 | 79511535 |
Completed suicide | 277.22 | 9.48 | 127 | 194900 | 245640 | 79303721 |
Clostridium difficile colitis | 274.53 | 9.48 | 366 | 194661 | 31917 | 79517444 |
Tendon discomfort | 229.84 | 9.48 | 73 | 194954 | 406 | 79548955 |
Clostridium difficile infection | 215.55 | 9.48 | 380 | 194647 | 42305 | 79507056 |
Pemphigus | 215.47 | 9.48 | 6 | 195021 | 99576 | 79449785 |
Death | 210.17 | 9.48 | 698 | 194329 | 565816 | 78983545 |
Tinnitus | 195.22 | 9.48 | 372 | 194655 | 43961 | 79505400 |
Myalgia | 192.90 | 9.48 | 932 | 194095 | 184709 | 79364652 |
Drug resistance | 186.85 | 9.48 | 355 | 194672 | 41858 | 79507503 |
Synovitis | 185.93 | 9.48 | 68 | 194959 | 150666 | 79398695 |
Rheumatoid arthritis | 175.44 | 9.48 | 151 | 194876 | 208319 | 79341042 |
Stevens-Johnson syndrome | 172.89 | 9.48 | 329 | 194698 | 38837 | 79510524 |
Drug abuse | 171.40 | 9.48 | 92 | 194935 | 162599 | 79386762 |
Acute kidney injury | 168.64 | 9.48 | 1976 | 193051 | 517428 | 79031933 |
Hand deformity | 164.52 | 9.48 | 28 | 194999 | 103891 | 79445470 |
Glossodynia | 156.81 | 9.48 | 31 | 194996 | 103306 | 79446055 |
Duodenal ulcer perforation | 143.19 | 9.48 | 4 | 195023 | 66207 | 79483154 |
Fall | 141.05 | 9.48 | 663 | 194364 | 486966 | 79062395 |
Pericarditis | 137.30 | 9.48 | 42 | 194985 | 104194 | 79445167 |
Rash maculo-papular | 132.51 | 9.48 | 368 | 194659 | 55710 | 79493651 |
Rheumatoid factor positive | 131.74 | 9.48 | 3 | 195024 | 59836 | 79489525 |
Fistula | 130.98 | 9.48 | 160 | 194867 | 12780 | 79536581 |
Maternal exposure during pregnancy | 130.07 | 9.48 | 87 | 194940 | 136451 | 79412910 |
Intentional overdose | 128.64 | 9.48 | 49 | 194978 | 105911 | 79443450 |
Helicobacter infection | 126.69 | 9.48 | 12 | 195015 | 69692 | 79479669 |
Dysbiosis | 123.11 | 9.48 | 60 | 194967 | 1159 | 79548202 |
Joint noise | 122.28 | 9.48 | 91 | 194936 | 3883 | 79545478 |
Anti-cyclic citrullinated peptide antibody positive | 119.90 | 9.48 | 28 | 194999 | 83115 | 79466246 |
Panic attack | 118.92 | 9.48 | 213 | 194814 | 24003 | 79525358 |
Infusion related reaction | 117.83 | 9.48 | 241 | 194786 | 229996 | 79319365 |
Paraesthesia | 114.41 | 9.48 | 781 | 194246 | 175542 | 79373819 |
Systemic lupus erythematosus | 112.98 | 9.48 | 79 | 194948 | 121070 | 79428291 |
Anxiety | 110.66 | 9.48 | 1009 | 194018 | 247503 | 79301858 |
Contraindicated product administered | 105.75 | 9.48 | 138 | 194889 | 157400 | 79391961 |
Torsade de pointes | 105.44 | 9.48 | 178 | 194849 | 19134 | 79530227 |
Hyperacusis | 104.21 | 9.48 | 66 | 194961 | 2157 | 79547204 |
Pseudomembranous colitis | 104.10 | 9.48 | 94 | 194933 | 5280 | 79544081 |
Tendon injury | 103.02 | 9.48 | 64 | 194963 | 2021 | 79547340 |
Anal fistula | 101.47 | 9.48 | 104 | 194923 | 6840 | 79542521 |
Choroiditis | 99.07 | 9.48 | 54 | 194973 | 1327 | 79548034 |
Eosinophilia | 97.83 | 9.48 | 288 | 194739 | 45057 | 79504304 |
Wound | 96.66 | 9.48 | 85 | 194942 | 116094 | 79433267 |
Acute generalised exanthematous pustulosis | 94.15 | 9.48 | 159 | 194868 | 17095 | 79532266 |
Toxicity to various agents | 94.07 | 9.48 | 624 | 194403 | 420916 | 79128445 |
Anal fissure | 90.83 | 9.48 | 103 | 194924 | 7600 | 79541761 |
Muscle atrophy | 90.39 | 9.48 | 124 | 194903 | 11108 | 79538253 |
Arthropathy | 90.08 | 9.48 | 186 | 194841 | 176925 | 79372436 |
Injection site pain | 86.86 | 9.48 | 114 | 194913 | 129724 | 79419637 |
Drug intolerance | 86.70 | 9.48 | 342 | 194685 | 263777 | 79285584 |
Pyrexia | 85.89 | 9.48 | 2219 | 192808 | 676490 | 78872871 |
Septic shock | 85.09 | 9.48 | 553 | 194474 | 122248 | 79427113 |
Nasopharyngitis | 84.45 | 9.48 | 327 | 194700 | 253554 | 79295807 |
Geotrichum infection | 83.50 | 9.48 | 43 | 194984 | 938 | 79548423 |
Connective tissue disorder | 83.36 | 9.48 | 48 | 194979 | 1315 | 79548046 |
Total lung capacity increased | 83.00 | 9.48 | 58 | 194969 | 2240 | 79547121 |
Discomfort | 81.29 | 9.48 | 113 | 194914 | 125504 | 79423857 |
Colitis | 78.18 | 9.48 | 371 | 194656 | 72936 | 79476425 |
Product dose omission issue | 77.19 | 9.48 | 327 | 194700 | 247210 | 79302151 |
Burning sensation | 77.16 | 9.48 | 316 | 194711 | 58316 | 79491045 |
Multiple organ dysfunction syndrome | 76.41 | 9.48 | 530 | 194497 | 119716 | 79429645 |
Alopecia | 76.29 | 9.48 | 299 | 194728 | 231056 | 79318305 |
Suicide attempt | 76.10 | 9.48 | 55 | 194972 | 82877 | 79466484 |
Early retirement | 75.92 | 9.48 | 16 | 195011 | 5 | 79549356 |
Photosensitivity reaction | 74.82 | 9.48 | 162 | 194865 | 20965 | 79528396 |
Pseudomonas infection | 73.71 | 9.48 | 160 | 194867 | 20743 | 79528618 |
Folliculitis | 73.49 | 9.48 | 22 | 195005 | 55358 | 79494003 |
Anal abscess | 71.87 | 9.48 | 101 | 194926 | 9254 | 79540107 |
Candida infection | 70.64 | 9.48 | 230 | 194797 | 37984 | 79511377 |
Abdominal pain | 69.83 | 9.48 | 1339 | 193688 | 388230 | 79161131 |
Clostridium test positive | 68.91 | 9.48 | 82 | 194945 | 6372 | 79542989 |
Impaired work ability | 68.66 | 9.48 | 150 | 194877 | 19531 | 79529830 |
Factor V inhibition | 68.21 | 9.48 | 28 | 194999 | 353 | 79549008 |
Henoch-Schonlein purpura | 68.02 | 9.48 | 55 | 194972 | 2655 | 79546706 |
Dermatitis exfoliative | 66.13 | 9.48 | 105 | 194922 | 10724 | 79538637 |
Hepatitis cholestatic | 65.67 | 9.48 | 120 | 194907 | 13732 | 79535629 |
Dysplastic naevus | 65.28 | 9.48 | 31 | 194996 | 564 | 79548797 |
Muscle twitching | 65.02 | 9.48 | 169 | 194858 | 24595 | 79524766 |
Coma | 64.66 | 9.48 | 91 | 194936 | 100558 | 79448803 |
Osteoporosis | 62.45 | 9.48 | 27 | 195000 | 54085 | 79495276 |
Eye pain | 62.24 | 9.48 | 218 | 194809 | 37360 | 79512001 |
Loss of employment | 61.77 | 9.48 | 51 | 194976 | 2536 | 79546825 |
Linear IgA disease | 61.09 | 9.48 | 55 | 194972 | 3077 | 79546284 |
Therapeutic product effect incomplete | 60.62 | 9.48 | 163 | 194864 | 141482 | 79407879 |
Food intolerance | 60.57 | 9.48 | 60 | 194967 | 3788 | 79545573 |
Neuropathy peripheral | 60.44 | 9.48 | 569 | 194458 | 140736 | 79408625 |
Fixed eruption | 59.85 | 9.48 | 53 | 194974 | 2901 | 79546460 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 59.77 | 9.48 | 55 | 194972 | 3166 | 79546195 |
Joint swelling | 59.06 | 9.48 | 438 | 194589 | 288208 | 79261153 |
Peripheral swelling | 58.63 | 9.48 | 402 | 194625 | 269215 | 79280146 |
Vanishing bile duct syndrome | 57.60 | 9.48 | 42 | 194985 | 1736 | 79547625 |
Cerebrovascular accident | 56.91 | 9.48 | 192 | 194835 | 155100 | 79394261 |
Psoriatic arthropathy | 56.90 | 9.48 | 64 | 194963 | 77935 | 79471426 |
Photodermatosis | 56.44 | 9.48 | 33 | 194994 | 931 | 79548430 |
Nephritis allergic | 56.44 | 9.48 | 30 | 194997 | 700 | 79548661 |
Muscle injury | 56.41 | 9.48 | 24 | 195003 | 48537 | 79500824 |
Therapeutic product effect decreased | 55.79 | 9.48 | 209 | 194818 | 163654 | 79385707 |
Malignant neoplasm progression | 55.59 | 9.48 | 160 | 194867 | 135830 | 79413531 |
Impaired healing | 55.56 | 9.48 | 80 | 194947 | 87575 | 79461786 |
Trimethylaminuria | 55.10 | 9.48 | 20 | 195007 | 176 | 79549185 |
Injection site erythema | 55.07 | 9.48 | 66 | 194961 | 78131 | 79471230 |
Exposure during pregnancy | 55.04 | 9.48 | 102 | 194925 | 101030 | 79448331 |
Cross sensitivity reaction | 54.97 | 9.48 | 56 | 194971 | 3656 | 79545705 |
Rash morbilliform | 54.24 | 9.48 | 71 | 194956 | 6079 | 79543282 |
Solar lentigo | 54.02 | 9.48 | 34 | 194993 | 1099 | 79548262 |
Renal tubular necrosis | 53.97 | 9.48 | 159 | 194868 | 24880 | 79524481 |
Weight increased | 53.88 | 9.48 | 427 | 194600 | 276959 | 79272402 |
Skin candida | 53.75 | 9.48 | 43 | 194984 | 2044 | 79547317 |
Spinal muscular atrophy | 53.61 | 9.48 | 24 | 195003 | 379 | 79548982 |
Abscess | 53.60 | 9.48 | 150 | 194877 | 22801 | 79526560 |
Type 2 diabetes mellitus | 53.57 | 9.48 | 37 | 194990 | 57085 | 79492276 |
Infective pulmonary exacerbation of cystic fibrosis | 53.10 | 9.48 | 105 | 194922 | 12746 | 79536615 |
Neuralgia | 53.00 | 9.48 | 191 | 194836 | 33193 | 79516168 |
Hepatic enzyme increased | 52.82 | 9.48 | 248 | 194779 | 182362 | 79366999 |
Aspergillus infection | 52.62 | 9.48 | 133 | 194894 | 19028 | 79530333 |
Injection site reaction | 52.03 | 9.48 | 35 | 194992 | 54750 | 79494611 |
Hyperfibrinolysis | 52.02 | 9.48 | 13 | 195014 | 23 | 79549338 |
COVID-19 | 51.81 | 9.48 | 204 | 194823 | 157470 | 79391891 |
Pulmonary pain | 51.37 | 9.48 | 59 | 194968 | 4414 | 79544947 |
Muscle rupture | 51.19 | 9.48 | 54 | 194973 | 3673 | 79545688 |
Myocardial infarction | 50.40 | 9.48 | 255 | 194772 | 183874 | 79365487 |
Segmental diverticular colitis | 49.83 | 9.48 | 18 | 195009 | 156 | 79549205 |
Psoriasis | 49.07 | 9.48 | 90 | 194937 | 89497 | 79459864 |
Cardio-respiratory arrest | 48.62 | 9.48 | 122 | 194905 | 108388 | 79440973 |
Rectal abscess | 48.55 | 9.48 | 41 | 194986 | 2104 | 79547257 |
Pedal pulse abnormal | 47.92 | 9.48 | 18 | 195009 | 176 | 79549185 |
Tracheobronchomegaly | 47.58 | 9.48 | 11 | 195016 | 11 | 79549350 |
Vulvovaginal burning sensation | 47.47 | 9.48 | 36 | 194991 | 1581 | 79547780 |
Cholecystitis chronic | 47.19 | 9.48 | 86 | 194941 | 9820 | 79539541 |
Leukocytosis | 47.11 | 9.48 | 221 | 194806 | 43234 | 79506127 |
Motor neurone disease | 47.04 | 9.48 | 25 | 195002 | 583 | 79548778 |
Megacolon | 46.87 | 9.48 | 50 | 194977 | 3445 | 79545916 |
Prescribed overdose | 46.84 | 9.48 | 17 | 195010 | 37866 | 79511495 |
Treatment failure | 46.72 | 9.48 | 236 | 194791 | 170250 | 79379111 |
Weight bearing difficulty | 46.63 | 9.48 | 48 | 194979 | 3173 | 79546188 |
Vitreous floaters | 46.59 | 9.48 | 72 | 194955 | 7184 | 79542177 |
Cardiac failure congestive | 46.30 | 9.48 | 185 | 194842 | 142217 | 79407144 |
Cystic fibrosis | 45.95 | 9.48 | 52 | 194975 | 3828 | 79545533 |
Toxic skin eruption | 45.63 | 9.48 | 139 | 194888 | 22154 | 79527207 |
Sphingomonas paucimobilis infection | 45.59 | 9.48 | 15 | 195012 | 95 | 79549266 |
Overdose | 45.51 | 9.48 | 264 | 194763 | 183942 | 79365419 |
Escherichia infection | 45.31 | 9.48 | 121 | 194906 | 17896 | 79531465 |
Sinusitis | 45.25 | 9.48 | 286 | 194741 | 195215 | 79354146 |
Enterococcal infection | 44.37 | 9.48 | 110 | 194917 | 15550 | 79533811 |
Accidental exposure to product | 44.27 | 9.48 | 11 | 195016 | 31311 | 79518050 |
Musculoskeletal injury | 43.89 | 9.48 | 17 | 195010 | 182 | 79549179 |
Device expulsion | 43.12 | 9.48 | 6 | 195021 | 25855 | 79523506 |
Disturbance in attention | 42.96 | 9.48 | 241 | 194786 | 50560 | 79498801 |
Infective aneurysm | 42.51 | 9.48 | 28 | 194999 | 980 | 79548381 |
Blood cholesterol increased | 42.47 | 9.48 | 88 | 194939 | 83632 | 79465729 |
Plantar fasciitis | 42.05 | 9.48 | 47 | 194980 | 3413 | 79545948 |
Stomatitis | 42.03 | 9.48 | 200 | 194827 | 146557 | 79402804 |
Therapeutic response decreased | 41.41 | 9.48 | 62 | 194965 | 66791 | 79482570 |
Injection site swelling | 41.01 | 9.48 | 33 | 194994 | 47099 | 79502262 |
Hip arthroplasty | 41.01 | 9.48 | 18 | 195009 | 35738 | 79513623 |
Wrong technique in product usage process | 40.65 | 9.48 | 74 | 194953 | 73801 | 79475560 |
Oesophageal spasm | 40.39 | 9.48 | 46 | 194981 | 3410 | 79545951 |
Abnormal palmar/plantar creases | 40.13 | 9.48 | 8 | 195019 | 0 | 79549361 |
Adverse event | 40.12 | 9.48 | 53 | 194974 | 60161 | 79489200 |
Increased bronchial secretion | 40.10 | 9.48 | 45 | 194982 | 3282 | 79546079 |
Sensory processing disorder | 39.98 | 9.48 | 9 | 195018 | 7 | 79549354 |
Product administration error | 39.87 | 9.48 | 14 | 195013 | 31832 | 79517529 |
Trichoglossia | 39.75 | 9.48 | 23 | 195004 | 636 | 79548725 |
Fat tissue decreased | 39.63 | 9.48 | 14 | 195013 | 113 | 79549248 |
Ligament pain | 39.63 | 9.48 | 17 | 195010 | 241 | 79549120 |
Incorrect route of product administration | 39.41 | 9.48 | 18 | 195009 | 34911 | 79514450 |
Febrile neutropenia | 39.30 | 9.48 | 788 | 194239 | 230211 | 79319150 |
Injection site bruising | 39.20 | 9.48 | 26 | 195001 | 40976 | 79508385 |
Acute myocardial infarction | 39.06 | 9.48 | 81 | 194946 | 76955 | 79472406 |
Intraocular pressure increased | 38.99 | 9.48 | 76 | 194951 | 9129 | 79540232 |
Drug-induced liver injury | 38.83 | 9.48 | 286 | 194741 | 65831 | 79483530 |
Swelling | 38.27 | 9.48 | 342 | 194685 | 216369 | 79332992 |
Penis injury | 38.20 | 9.48 | 14 | 195013 | 127 | 79549234 |
Pouchitis | 38.17 | 9.48 | 26 | 195001 | 963 | 79548398 |
Skin injury | 37.56 | 9.48 | 44 | 194983 | 3362 | 79545999 |
Diarrhoea | 37.31 | 9.48 | 2564 | 192463 | 877925 | 78671436 |
Muscle contractions involuntary | 37.21 | 9.48 | 46 | 194981 | 3719 | 79545642 |
Stoma closure | 36.68 | 9.48 | 17 | 195010 | 292 | 79549069 |
Lower respiratory tract infection bacterial | 36.58 | 9.48 | 25 | 195002 | 931 | 79548430 |
Nervous system disorder | 36.32 | 9.48 | 146 | 194881 | 26710 | 79522651 |
Abdominal pain lower | 36.20 | 9.48 | 164 | 194863 | 31618 | 79517743 |
Cholestatic liver injury | 35.98 | 9.48 | 52 | 194975 | 4889 | 79544472 |
Bradycardia | 35.81 | 9.48 | 190 | 194837 | 135367 | 79413994 |
Product substitution issue | 35.48 | 9.48 | 4 | 195023 | 20252 | 79529109 |
Nasal polyps | 35.40 | 9.48 | 64 | 194963 | 7263 | 79542098 |
Thrombocytopenia | 35.37 | 9.48 | 874 | 194153 | 264385 | 79284976 |
Intentional product misuse | 35.31 | 9.48 | 117 | 194910 | 95048 | 79454313 |
Chronic fatigue syndrome | 35.22 | 9.48 | 28 | 194999 | 1319 | 79548042 |
Nasal oedema | 35.06 | 9.48 | 31 | 194996 | 1693 | 79547668 |
Depersonalisation/derealisation disorder | 34.95 | 9.48 | 32 | 194995 | 1830 | 79547531 |
Fistula discharge | 34.83 | 9.48 | 28 | 194999 | 1340 | 79548021 |
Emotional distress | 34.72 | 9.48 | 191 | 194836 | 39778 | 79509583 |
Diastasis recti abdominis | 34.66 | 9.48 | 9 | 195018 | 20 | 79549341 |
Hypertension | 34.62 | 9.48 | 585 | 194442 | 330407 | 79218954 |
Hallucination | 34.54 | 9.48 | 341 | 194686 | 85404 | 79463957 |
Acinetobacter infection | 34.23 | 9.48 | 38 | 194989 | 2739 | 79546622 |
Dermatitis bullous | 34.15 | 9.48 | 94 | 194933 | 14151 | 79535210 |
Calcium ionised decreased | 34.12 | 9.48 | 20 | 195007 | 567 | 79548794 |
Abdominal abscess | 34.11 | 9.48 | 62 | 194965 | 7065 | 79542296 |
Urinary tract infection | 33.82 | 9.48 | 895 | 194132 | 273617 | 79275744 |
Cutaneous vasculitis | 33.58 | 9.48 | 67 | 194960 | 8185 | 79541176 |
Depressed level of consciousness | 33.06 | 9.48 | 123 | 194904 | 96529 | 79452832 |
Staphylococcal infection | 33.01 | 9.48 | 250 | 194777 | 58045 | 79491316 |
Aortic valve prolapse | 32.83 | 9.48 | 8 | 195019 | 12 | 79549349 |
Yellow fever | 32.62 | 9.48 | 7 | 195020 | 3 | 79549358 |
Oesophageal pain | 32.58 | 9.48 | 46 | 194981 | 4233 | 79545128 |
Female genital tract fistula | 32.52 | 9.48 | 55 | 194972 | 5920 | 79543441 |
Hepatic encephalopathy | 32.38 | 9.48 | 131 | 194896 | 24035 | 79525326 |
Lung consolidation | 32.13 | 9.48 | 69 | 194958 | 8878 | 79540483 |
Live birth | 32.09 | 9.48 | 4 | 195023 | 18740 | 79530621 |
Ill-defined disorder | 31.95 | 9.48 | 71 | 194956 | 65804 | 79483557 |
Prostatitis | 31.74 | 9.48 | 45 | 194982 | 4157 | 79545204 |
Contusion | 31.73 | 9.48 | 223 | 194804 | 148553 | 79400808 |
Procedural anxiety | 31.63 | 9.48 | 21 | 195006 | 745 | 79548616 |
Pregnancy | 31.62 | 9.48 | 13 | 195014 | 26838 | 79522523 |
Factor V deficiency | 31.55 | 9.48 | 11 | 195016 | 85 | 79549276 |
Crystal nephropathy | 31.28 | 9.48 | 27 | 195000 | 1428 | 79547933 |
Diverticulitis | 31.27 | 9.48 | 206 | 194821 | 45730 | 79503631 |
Klebsiella infection | 31.23 | 9.48 | 97 | 194930 | 15623 | 79533738 |
Palpitations | 30.98 | 9.48 | 458 | 194569 | 126152 | 79423209 |
Multiple sclerosis relapse | 30.96 | 9.48 | 41 | 194986 | 46492 | 79502869 |
Escherichia urinary tract infection | 30.96 | 9.48 | 89 | 194938 | 13736 | 79535625 |
Lymphoedema | 30.85 | 9.48 | 83 | 194944 | 12330 | 79537031 |
Mobility decreased | 30.75 | 9.48 | 174 | 194853 | 122001 | 79427360 |
Muscle tightness | 30.74 | 9.48 | 85 | 194942 | 12829 | 79536532 |
Paraesthesia oral | 30.71 | 9.48 | 115 | 194912 | 20356 | 79529005 |
Undersensing | 30.28 | 9.48 | 7 | 195020 | 7 | 79549354 |
Mineral deficiency | 30.17 | 9.48 | 9 | 195018 | 39 | 79549322 |
Poisoning | 30.14 | 9.48 | 12 | 195015 | 25260 | 79524101 |
Sputum increased | 29.94 | 9.48 | 46 | 194981 | 4567 | 79544794 |
Pulmonary arterial hypertension | 29.91 | 9.48 | 16 | 195011 | 28350 | 79521011 |
Sepsis | 29.69 | 9.48 | 866 | 194161 | 268562 | 79280799 |
Haematospermia | 29.42 | 9.48 | 14 | 195013 | 256 | 79549105 |
Abdominal discomfort | 29.27 | 9.48 | 434 | 194593 | 250293 | 79299068 |
Fungaemia | 28.70 | 9.48 | 45 | 194982 | 4546 | 79544815 |
Cystitis | 28.66 | 9.48 | 224 | 194803 | 52508 | 79496853 |
Hyphaema | 28.49 | 9.48 | 21 | 195006 | 883 | 79548478 |
Visual acuity reduced | 28.45 | 9.48 | 145 | 194882 | 29324 | 79520037 |
Non-consummation | 28.34 | 9.48 | 9 | 195018 | 50 | 79549311 |
Anorectal ulcer | 28.34 | 9.48 | 9 | 195018 | 50 | 79549311 |
Visual impairment | 28.19 | 9.48 | 347 | 194680 | 91784 | 79457577 |
Pneumococcal sepsis | 28.19 | 9.48 | 27 | 195000 | 1635 | 79547726 |
Drug dependence | 28.08 | 9.48 | 35 | 194992 | 40734 | 79508627 |
Neutropenia | 28.04 | 9.48 | 911 | 194116 | 286799 | 79262562 |
Rash erythematous | 27.95 | 9.48 | 239 | 194788 | 57530 | 79491831 |
Drug ineffective | 27.94 | 9.48 | 2271 | 192756 | 1078642 | 78470719 |
Hepatic cytolysis | 27.92 | 9.48 | 136 | 194891 | 27015 | 79522346 |
Flushing | 27.85 | 9.48 | 116 | 194911 | 88152 | 79461209 |
Penile haemorrhage | 27.85 | 9.48 | 17 | 195010 | 520 | 79548841 |
Pancreatic enzyme abnormality | 27.82 | 9.48 | 11 | 195016 | 125 | 79549236 |
Acute hepatic failure | 27.57 | 9.48 | 146 | 194881 | 29967 | 79519394 |
Pulmonary hypertension | 27.50 | 9.48 | 47 | 194980 | 48033 | 79501328 |
Somnolence | 27.44 | 9.48 | 415 | 194612 | 238566 | 79310795 |
Sarcoidosis | 27.36 | 9.48 | 62 | 194965 | 8273 | 79541088 |
Oliguria | 27.34 | 9.48 | 95 | 194932 | 16214 | 79533147 |
Blood glucose increased | 27.21 | 9.48 | 167 | 194860 | 114808 | 79434553 |
Bladder pain | 27.13 | 9.48 | 31 | 194996 | 2306 | 79547055 |
Phlebitis | 27.13 | 9.48 | 64 | 194963 | 8766 | 79540595 |
Hypotony of eye | 26.96 | 9.48 | 13 | 195014 | 245 | 79549116 |
Dysuria | 26.90 | 9.48 | 215 | 194812 | 50736 | 79498625 |
Osteonecrosis of jaw | 26.85 | 9.48 | 40 | 194987 | 43186 | 79506175 |
Intentional self-injury | 26.61 | 9.48 | 24 | 195003 | 32395 | 79516966 |
Cholestasis | 26.49 | 9.48 | 218 | 194809 | 51891 | 79497470 |
Skin burning sensation | 26.46 | 9.48 | 82 | 194945 | 13190 | 79536171 |
Sopor | 26.43 | 9.48 | 25 | 195002 | 32985 | 79516376 |
Corneal deposits | 26.43 | 9.48 | 16 | 195011 | 482 | 79548879 |
Mucosal inflammation | 26.39 | 9.48 | 292 | 194735 | 75288 | 79474073 |
Polyneuropathy | 26.30 | 9.48 | 123 | 194904 | 24028 | 79525333 |
Off label use | 26.26 | 9.48 | 1888 | 193139 | 905327 | 78644034 |
Foot deformity | 26.25 | 9.48 | 13 | 195014 | 24061 | 79525300 |
Radiation inflammation | 26.24 | 9.48 | 20 | 195007 | 885 | 79548476 |
Corneal opacity | 26.23 | 9.48 | 21 | 195006 | 999 | 79548362 |
Pudendal canal syndrome | 25.95 | 9.48 | 6 | 195021 | 6 | 79549355 |
Hypoaesthesia | 25.73 | 9.48 | 597 | 194430 | 178755 | 79370606 |
Rhinitis allergic | 25.58 | 9.48 | 77 | 194950 | 12192 | 79537169 |
Lymphocyte count decreased | 25.45 | 9.48 | 48 | 194979 | 47241 | 79502120 |
Cardiac failure | 25.34 | 9.48 | 249 | 194778 | 154593 | 79394768 |
Sedation complication | 25.29 | 9.48 | 4 | 195023 | 15665 | 79533696 |
Moraxella test positive | 25.22 | 9.48 | 7 | 195020 | 22 | 79549339 |
Hypotension | 25.20 | 9.48 | 853 | 194174 | 439464 | 79109897 |
Lividity | 25.19 | 9.48 | 15 | 195012 | 438 | 79548923 |
Right ventricular failure | 25.15 | 9.48 | 13 | 195014 | 23484 | 79525877 |
Yellow fever vaccine-associated viscerotropic disease | 25.08 | 9.48 | 5 | 195022 | 0 | 79549361 |
Right ventricle outflow tract obstruction | 25.08 | 9.48 | 5 | 195022 | 0 | 79549361 |
Cholelithiasis | 25.02 | 9.48 | 217 | 194810 | 52447 | 79496914 |
Night sweats | 24.93 | 9.48 | 215 | 194812 | 51880 | 79497481 |
Feeding intolerance | 24.92 | 9.48 | 19 | 195008 | 841 | 79548520 |
Femur fracture | 24.76 | 9.48 | 35 | 194992 | 38617 | 79510744 |
Abscess intestinal | 24.63 | 9.48 | 32 | 194995 | 2719 | 79546642 |
Nerve injury | 24.56 | 9.48 | 64 | 194963 | 9328 | 79540033 |
Sciatica | 24.51 | 9.48 | 27 | 195000 | 33195 | 79516166 |
Injection site pruritus | 24.49 | 9.48 | 41 | 194986 | 42242 | 79507119 |
Symmetrical drug-related intertriginous and flexural exanthema | 24.42 | 9.48 | 19 | 195008 | 867 | 79548494 |
Osteonecrosis | 24.38 | 9.48 | 24 | 195003 | 31071 | 79518290 |
Trichosporon infection | 24.34 | 9.48 | 20 | 195007 | 988 | 79548373 |
Device malfunction | 24.28 | 9.48 | 11 | 195016 | 21437 | 79527924 |
Amyloid arthropathy | 24.19 | 9.48 | 16 | 195011 | 564 | 79548797 |
Systemic inflammatory response syndrome | 23.94 | 9.48 | 72 | 194955 | 11393 | 79537968 |
Mitochondrial cytopathy | 23.91 | 9.48 | 14 | 195013 | 396 | 79548965 |
Thrombotic thrombocytopenic purpura | 23.86 | 9.48 | 50 | 194977 | 6326 | 79543035 |
Meningitis candida | 23.82 | 9.48 | 10 | 195017 | 134 | 79549227 |
Pyelonephritis | 23.81 | 9.48 | 106 | 194921 | 20282 | 79529079 |
Flank pain | 23.81 | 9.48 | 104 | 194923 | 19740 | 79529621 |
Transient ischaemic attack | 23.79 | 9.48 | 59 | 194968 | 52636 | 79496725 |
Sensory disturbance | 23.71 | 9.48 | 86 | 194941 | 14991 | 79534370 |
Transmission of an infectious agent via product | 23.68 | 9.48 | 11 | 195016 | 190 | 79549171 |
Aortic aneurysm | 23.58 | 9.48 | 59 | 194968 | 8387 | 79540974 |
Fracture | 23.43 | 9.48 | 12 | 195015 | 21789 | 79527572 |
Hallucinations, mixed | 23.41 | 9.48 | 52 | 194975 | 6847 | 79542514 |
Injection site warmth | 23.40 | 9.48 | 4 | 195023 | 14803 | 79534558 |
Ectropion | 23.35 | 9.48 | 14 | 195013 | 414 | 79548947 |
Coronary artery disease | 23.26 | 9.48 | 82 | 194945 | 65392 | 79483969 |
Breast cancer | 23.26 | 9.48 | 29 | 194998 | 33752 | 79515609 |
Bacterial colitis | 23.18 | 9.48 | 9 | 195018 | 97 | 79549264 |
Collagen disorder | 23.09 | 9.48 | 12 | 195015 | 267 | 79549094 |
Erythema | 23.05 | 9.48 | 712 | 194315 | 222578 | 79326783 |
Injection site hyperaesthesia | 23.04 | 9.48 | 8 | 195019 | 61 | 79549300 |
Gastrointestinal infection | 23.02 | 9.48 | 71 | 194956 | 11390 | 79537971 |
Potentiating drug interaction | 22.96 | 9.48 | 60 | 194967 | 8759 | 79540602 |
Prescribed underdose | 22.88 | 9.48 | 23 | 195004 | 29491 | 79519870 |
Depression | 22.84 | 9.48 | 693 | 194334 | 216097 | 79333264 |
Clostridial infection | 22.78 | 9.48 | 46 | 194981 | 5668 | 79543693 |
Loss of personal independence in daily activities | 22.74 | 9.48 | 152 | 194875 | 102428 | 79446933 |
Lumbosacral plexus injury | 22.62 | 9.48 | 6 | 195021 | 15 | 79549346 |
Lip dry | 22.61 | 9.48 | 5 | 195022 | 15413 | 79533948 |
Urosepsis | 22.60 | 9.48 | 126 | 194901 | 26369 | 79522992 |
Ependymoma | 22.60 | 9.48 | 8 | 195019 | 65 | 79549296 |
Single functional kidney | 22.54 | 9.48 | 12 | 195015 | 281 | 79549080 |
Chest injury | 22.48 | 9.48 | 31 | 194996 | 2790 | 79546571 |
Product quality issue | 22.48 | 9.48 | 30 | 194997 | 33910 | 79515451 |
Nosocomial infection | 22.39 | 9.48 | 31 | 194996 | 2801 | 79546560 |
Stenotrophomonas infection | 22.24 | 9.48 | 36 | 194991 | 3737 | 79545624 |
Diaphragmatic rupture | 22.22 | 9.48 | 11 | 195016 | 220 | 79549141 |
Catatonia | 22.21 | 9.48 | 59 | 194968 | 8697 | 79540664 |
Asthma | 22.20 | 9.48 | 217 | 194810 | 134878 | 79414483 |
Toxic encephalopathy | 22.18 | 9.48 | 70 | 194957 | 11370 | 79537991 |
Agranulocytosis | 22.15 | 9.48 | 187 | 194840 | 44843 | 79504518 |
Aortic aneurysm rupture | 21.89 | 9.48 | 21 | 195006 | 1274 | 79548087 |
Injection site mass | 21.85 | 9.48 | 11 | 195016 | 20173 | 79529188 |
Septic embolus | 21.80 | 9.48 | 26 | 195001 | 2025 | 79547336 |
Angina pectoris | 21.77 | 9.48 | 60 | 194967 | 51672 | 79497689 |
Hyperkalaemia | 21.77 | 9.48 | 177 | 194850 | 114221 | 79435140 |
Electrocardiogram QT prolonged | 21.73 | 9.48 | 326 | 194701 | 90060 | 79459301 |
Tendon necrosis | 21.63 | 9.48 | 5 | 195022 | 5 | 79549356 |
Long QT syndrome | 21.47 | 9.48 | 46 | 194981 | 5909 | 79543452 |
Confabulation | 21.41 | 9.48 | 14 | 195013 | 484 | 79548877 |
Gastrointestinal inflammation | 21.38 | 9.48 | 53 | 194974 | 7491 | 79541870 |
Hypomania | 21.38 | 9.48 | 53 | 194974 | 7491 | 79541870 |
Orchitis | 21.27 | 9.48 | 21 | 195006 | 1320 | 79548041 |
Underdose | 21.26 | 9.48 | 30 | 194997 | 33121 | 79516240 |
Documented hypersensitivity to administered product | 21.23 | 9.48 | 18 | 195009 | 929 | 79548432 |
Ischaemic stroke | 21.23 | 9.48 | 30 | 194997 | 33101 | 79516260 |
Staphylococcal scalded skin syndrome | 21.23 | 9.48 | 13 | 195014 | 400 | 79548961 |
Road traffic accident | 21.22 | 9.48 | 47 | 194980 | 43617 | 79505744 |
Thrombocytosis | 21.18 | 9.48 | 57 | 194970 | 8469 | 79540892 |
Vulvovaginal pruritus | 21.08 | 9.48 | 29 | 194998 | 2604 | 79546757 |
Idiosyncratic drug reaction | 21.06 | 9.48 | 21 | 195006 | 1336 | 79548025 |
Haematuria | 20.94 | 9.48 | 259 | 194768 | 68577 | 79480784 |
Jaundice cholestatic | 20.92 | 9.48 | 68 | 194959 | 11216 | 79538145 |
Walking disability | 20.88 | 9.48 | 26 | 195001 | 2117 | 79547244 |
Tooth disorder | 20.85 | 9.48 | 20 | 195007 | 26213 | 79523148 |
Auditory disorder | 20.73 | 9.48 | 14 | 195013 | 511 | 79548850 |
COVID-19 pneumonia | 20.68 | 9.48 | 24 | 195003 | 28825 | 79520536 |
Pulmonary eosinophilia | 20.66 | 9.48 | 16 | 195011 | 725 | 79548636 |
Herpes zoster | 20.59 | 9.48 | 138 | 194889 | 92945 | 79456416 |
Bone marrow granuloma | 20.50 | 9.48 | 6 | 195021 | 24 | 79549337 |
Excessive eye blinking | 20.49 | 9.48 | 23 | 195004 | 1678 | 79547683 |
Hyperinsulinaemia | 20.34 | 9.48 | 10 | 195017 | 197 | 79549164 |
Myosclerosis | 20.29 | 9.48 | 10 | 195017 | 198 | 79549163 |
Acute febrile neutrophilic dermatosis | 20.23 | 9.48 | 35 | 194992 | 3837 | 79545524 |
Drug level increased | 20.22 | 9.48 | 166 | 194861 | 39485 | 79509876 |
Sleep disorder due to a general medical condition | 20.20 | 9.48 | 5 | 195022 | 14272 | 79535089 |
Scleromalacia | 20.09 | 9.48 | 7 | 195020 | 54 | 79549307 |
Tendon laxity | 20.06 | 9.48 | 4 | 195023 | 0 | 79549361 |
Yellow fever vaccine-associated neurotropic disease | 20.06 | 9.48 | 4 | 195023 | 0 | 79549361 |
Renal vein compression | 20.06 | 9.48 | 4 | 195023 | 0 | 79549361 |
Posterior tibial tendon dysfunction | 20.06 | 9.48 | 4 | 195023 | 0 | 79549361 |
Osteoarthritis | 20.04 | 9.48 | 128 | 194899 | 87181 | 79462180 |
Hypophosphataemia | 19.89 | 9.48 | 12 | 195015 | 19901 | 79529460 |
Disease progression | 19.86 | 9.48 | 324 | 194703 | 184038 | 79365323 |
Diabetic ketoacidosis | 19.84 | 9.48 | 33 | 194994 | 34089 | 79515272 |
Drug ineffective for unapproved indication | 19.78 | 9.48 | 202 | 194825 | 51036 | 79498325 |
Inappropriate antidiuretic hormone secretion | 19.76 | 9.48 | 121 | 194906 | 26192 | 79523169 |
Aeromonas infection | 19.75 | 9.48 | 12 | 195015 | 364 | 79548997 |
Influenza | 19.73 | 9.48 | 212 | 194815 | 129394 | 79419967 |
Hepatitis infectious mononucleosis | 19.72 | 9.48 | 9 | 195018 | 149 | 79549212 |
Intestinal stenosis | 19.70 | 9.48 | 34 | 194993 | 3720 | 79545641 |
Post infection glomerulonephritis | 19.70 | 9.48 | 8 | 195019 | 98 | 79549263 |
Rectal tube insertion | 19.61 | 9.48 | 5 | 195022 | 10 | 79549351 |
Haemorrhagic vasculitis | 19.55 | 9.48 | 8 | 195019 | 100 | 79549261 |
Ligament disorder | 19.54 | 9.48 | 12 | 195015 | 371 | 79548990 |
Neoplasm progression | 19.54 | 9.48 | 63 | 194964 | 51619 | 79497742 |
Bronchiectasis | 19.45 | 9.48 | 107 | 194920 | 22279 | 79527082 |
Headache | 19.45 | 9.48 | 1357 | 193670 | 652415 | 78896946 |
Myoclonus | 19.41 | 9.48 | 125 | 194902 | 27535 | 79521826 |
Dyspnoea | 19.37 | 9.48 | 1819 | 193208 | 855206 | 78694155 |
Chronic gastrointestinal bleeding | 19.36 | 9.48 | 13 | 195014 | 470 | 79548891 |
Bronchial disorder | 19.31 | 9.48 | 27 | 195000 | 2462 | 79546899 |
Sudden death | 19.29 | 9.48 | 16 | 195011 | 22495 | 79526866 |
Uveitis | 19.28 | 9.48 | 87 | 194940 | 16743 | 79532618 |
Leukocyturia | 19.23 | 9.48 | 24 | 195003 | 1959 | 79547402 |
Cerebral infarction | 19.20 | 9.48 | 53 | 194974 | 45623 | 79503738 |
Basal cell carcinoma | 19.20 | 9.48 | 39 | 194988 | 37336 | 79512025 |
Faciobrachial dystonic seizure | 19.15 | 9.48 | 7 | 195020 | 63 | 79549298 |
Fear of death | 19.13 | 9.48 | 21 | 195006 | 1495 | 79547866 |
Staphylococcal sepsis | 19.08 | 9.48 | 79 | 194948 | 14647 | 79534714 |
Myopathy | 19.03 | 9.48 | 100 | 194927 | 20463 | 79528898 |
Graft versus host disease | 18.99 | 9.48 | 80 | 194947 | 14946 | 79534415 |
Pyelonephritis fungal | 18.98 | 9.48 | 10 | 195017 | 229 | 79549132 |
Joint ankylosis | 18.96 | 9.48 | 25 | 195002 | 2155 | 79547206 |
Pancytopenia | 18.86 | 9.48 | 535 | 194492 | 165210 | 79384151 |
Dyslexia | 18.82 | 9.48 | 10 | 195017 | 233 | 79549128 |
Hospitalisation | 18.76 | 9.48 | 144 | 194883 | 94092 | 79455269 |
Troponin increased | 18.69 | 9.48 | 12 | 195015 | 19243 | 79530118 |
Limb immobilisation | 18.68 | 9.48 | 7 | 195020 | 68 | 79549293 |
Bacterial endophthalmitis | 18.60 | 9.48 | 9 | 195018 | 171 | 79549190 |
Chemical burns of eye | 18.55 | 9.48 | 8 | 195019 | 115 | 79549246 |
Face oedema | 18.44 | 9.48 | 125 | 194902 | 28011 | 79521350 |
Histamine intolerance | 18.37 | 9.48 | 6 | 195021 | 37 | 79549324 |
Respiratory tract infection bacterial | 18.35 | 9.48 | 24 | 195003 | 2053 | 79547308 |
Cardiac arrest | 18.35 | 9.48 | 303 | 194724 | 171793 | 79377568 |
Pneumonia pseudomonal | 18.33 | 9.48 | 43 | 194984 | 5868 | 79543493 |
Renal injury | 18.28 | 9.48 | 86 | 194941 | 16841 | 79532520 |
Vaccination site reaction | 18.18 | 9.48 | 8 | 195019 | 121 | 79549240 |
Epididymitis | 18.15 | 9.48 | 23 | 195004 | 1907 | 79547454 |
Rash | 18.13 | 9.48 | 1646 | 193381 | 576712 | 78972649 |
Jaundice | 18.12 | 9.48 | 205 | 194822 | 53144 | 79496217 |
Food allergy | 18.10 | 9.48 | 63 | 194964 | 10761 | 79538600 |
Anuria | 18.08 | 9.48 | 100 | 194927 | 20863 | 79528498 |
Frequent bowel movements | 18.04 | 9.48 | 129 | 194898 | 29410 | 79519951 |
Small fibre neuropathy | 17.92 | 9.48 | 13 | 195014 | 533 | 79548828 |
Hypercholesterolaemia | 17.90 | 9.48 | 18 | 195009 | 23077 | 79526284 |
Bladder hypertrophy | 17.88 | 9.48 | 14 | 195013 | 645 | 79548716 |
Spinal fracture | 17.87 | 9.48 | 11 | 195016 | 18043 | 79531318 |
Hypersensitivity vasculitis | 17.83 | 9.48 | 47 | 194980 | 6896 | 79542465 |
Hyperpathia | 17.83 | 9.48 | 4 | 195023 | 3 | 79549358 |
Anhedonia | 17.81 | 9.48 | 78 | 194949 | 14820 | 79534541 |
Pruritus genital | 17.75 | 9.48 | 36 | 194991 | 4450 | 79544911 |
Irritable bowel syndrome | 17.70 | 9.48 | 85 | 194942 | 62156 | 79487205 |
Corynebacterium infection | 17.69 | 9.48 | 19 | 195008 | 1319 | 79548042 |
Intestinal dilatation | 17.63 | 9.48 | 27 | 195000 | 2673 | 79546688 |
Mouth ulceration | 17.61 | 9.48 | 157 | 194870 | 38237 | 79511124 |
C-reactive protein abnormal | 17.57 | 9.48 | 60 | 194967 | 48307 | 79501054 |
Muscular weakness | 17.52 | 9.48 | 516 | 194511 | 160213 | 79389148 |
Ischaemic cerebral infarction | 17.47 | 9.48 | 26 | 195001 | 2509 | 79546852 |
Deafness bilateral | 17.40 | 9.48 | 24 | 195003 | 2161 | 79547200 |
Biliary dyskinesia | 17.40 | 9.48 | 26 | 195001 | 2519 | 79546842 |
Nail bed bleeding | 17.38 | 9.48 | 14 | 195013 | 672 | 79548689 |
Generalised tonic-clonic seizure | 17.37 | 9.48 | 174 | 194853 | 43736 | 79505625 |
Restlessness | 17.33 | 9.48 | 182 | 194845 | 46310 | 79503051 |
Product use issue | 17.29 | 9.48 | 386 | 194641 | 209436 | 79339925 |
Exercise tolerance decreased | 17.12 | 9.48 | 55 | 194972 | 9016 | 79540345 |
Anal paraesthesia | 17.08 | 9.48 | 5 | 195022 | 20 | 79549341 |
Necrotising retinitis | 17.03 | 9.48 | 18 | 195009 | 1227 | 79548134 |
Lip erosion | 16.95 | 9.48 | 20 | 195007 | 1540 | 79547821 |
Diabetes mellitus | 16.95 | 9.48 | 117 | 194910 | 78273 | 79471088 |
Diabetic macroangiopathy | 16.92 | 9.48 | 8 | 195019 | 144 | 79549217 |
Thermal burn | 16.92 | 9.48 | 47 | 194980 | 7113 | 79542248 |
Metastases to liver | 16.82 | 9.48 | 27 | 195000 | 28287 | 79521074 |
Panic reaction | 16.78 | 9.48 | 36 | 194991 | 4629 | 79544732 |
SARS-CoV-2 test positive | 16.78 | 9.48 | 4 | 195023 | 11712 | 79537649 |
Skin oedema | 16.77 | 9.48 | 21 | 195006 | 1720 | 79547641 |
Head injury | 16.74 | 9.48 | 42 | 194985 | 37327 | 79512034 |
Bacteriuria | 16.72 | 9.48 | 18 | 195009 | 1253 | 79548108 |
Red blood cell count decreased | 16.68 | 9.48 | 78 | 194949 | 57435 | 79491926 |
Therapy partial responder | 16.67 | 9.48 | 11 | 195016 | 17386 | 79531975 |
Gastroenteritis staphylococcal | 16.61 | 9.48 | 10 | 195017 | 298 | 79549063 |
Atrioventricular block complete | 16.61 | 9.48 | 10 | 195017 | 16600 | 79532761 |
Hypogonadism | 16.59 | 9.48 | 21 | 195006 | 1739 | 79547622 |
Dermatitis exfoliative generalised | 16.59 | 9.48 | 47 | 194980 | 7194 | 79542167 |
Intestinal fistula | 16.57 | 9.48 | 19 | 195008 | 1419 | 79547942 |
Proctalgia | 16.54 | 9.48 | 58 | 194969 | 9943 | 79539418 |
Necrosis | 16.53 | 9.48 | 56 | 194971 | 9437 | 79539924 |
May-Thurner syndrome | 16.52 | 9.48 | 5 | 195022 | 23 | 79549338 |
Anorectal disorder | 16.50 | 9.48 | 24 | 195003 | 2269 | 79547092 |
Sedation | 16.49 | 9.48 | 68 | 194959 | 51827 | 79497534 |
International normalised ratio increased | 16.44 | 9.48 | 295 | 194732 | 84426 | 79464935 |
Enterocutaneous fistula | 16.31 | 9.48 | 22 | 195005 | 1939 | 79547422 |
Bursitis | 16.28 | 9.48 | 40 | 194987 | 35804 | 79513557 |
Procalcitonin decreased | 16.27 | 9.48 | 7 | 195020 | 100 | 79549261 |
Post transplant lymphoproliferative disorder | 16.25 | 9.48 | 4 | 195023 | 11460 | 79537901 |
General physical health deterioration | 16.24 | 9.48 | 531 | 194496 | 274707 | 79274654 |
Oxygen saturation decreased | 16.24 | 9.48 | 220 | 194807 | 128827 | 79420534 |
Vulvovaginal swelling | 16.23 | 9.48 | 11 | 195016 | 404 | 79548957 |
Infusion site streaking | 16.04 | 9.48 | 12 | 195015 | 516 | 79548845 |
Gluten sensitivity | 16.04 | 9.48 | 11 | 195016 | 412 | 79548949 |
Bladder trabeculation | 16.04 | 9.48 | 6 | 195021 | 58 | 79549303 |
Joint range of motion decreased | 16.03 | 9.48 | 36 | 194991 | 33246 | 79516115 |
Swelling face | 16.03 | 9.48 | 254 | 194773 | 70958 | 79478403 |
Subdural haematoma | 15.97 | 9.48 | 33 | 194994 | 31401 | 79517960 |
Necrotising scleritis | 15.95 | 9.48 | 9 | 195018 | 237 | 79549124 |
Gastroenteritis pseudomonas | 15.94 | 9.48 | 6 | 195021 | 59 | 79549302 |
Acute psychosis | 15.90 | 9.48 | 33 | 194994 | 4147 | 79545214 |
Leukopenia | 15.83 | 9.48 | 385 | 194642 | 116128 | 79433233 |
Systemic candida | 15.83 | 9.48 | 44 | 194983 | 6662 | 79542699 |
Cardiac disorder | 15.82 | 9.48 | 95 | 194932 | 65662 | 79483699 |
Therapy non-responder | 15.70 | 9.48 | 147 | 194880 | 92158 | 79457203 |
Blood pressure increased | 15.70 | 9.48 | 395 | 194632 | 210965 | 79338396 |
Intestinal intraepithelial lymphocytes increased | 15.64 | 9.48 | 8 | 195019 | 172 | 79549189 |
Withdrawal syndrome | 15.59 | 9.48 | 26 | 195001 | 26828 | 79522533 |
Knee arthroplasty | 15.47 | 9.48 | 54 | 194973 | 43194 | 79506167 |
Dysaesthesia | 15.44 | 9.48 | 40 | 194987 | 5808 | 79543553 |
Adverse drug reaction | 15.41 | 9.48 | 97 | 194930 | 66295 | 79483066 |
Cytokine release syndrome | 15.40 | 9.48 | 145 | 194882 | 35853 | 79513508 |
Adverse reaction | 15.39 | 9.48 | 54 | 194973 | 9260 | 79540101 |
Idiopathic intracranial hypertension | 15.38 | 9.48 | 28 | 194999 | 3194 | 79546167 |
Product contamination microbial | 15.35 | 9.48 | 15 | 195012 | 931 | 79548430 |
Prothrombin time shortened | 15.34 | 9.48 | 28 | 194999 | 3200 | 79546161 |
White blood cell count decreased | 15.33 | 9.48 | 347 | 194680 | 187941 | 79361420 |
Mucosal hyperaemia | 15.27 | 9.48 | 6 | 195021 | 67 | 79549294 |
Tongue geographic | 15.27 | 9.48 | 6 | 195021 | 67 | 79549294 |
Hypoglossal nerve paresis | 15.22 | 9.48 | 7 | 195020 | 118 | 79549243 |
Gastrointestinal scarring | 15.18 | 9.48 | 10 | 195017 | 350 | 79549011 |
Tachypnoea | 15.17 | 9.48 | 132 | 194895 | 31931 | 79517430 |
Lymphadenectomy | 15.13 | 9.48 | 17 | 195010 | 1242 | 79548119 |
Intrauterine infection | 15.11 | 9.48 | 6 | 195021 | 69 | 79549292 |
C-reactive protein decreased | 15.11 | 9.48 | 25 | 195002 | 2643 | 79546718 |
Swollen tongue | 15.10 | 9.48 | 165 | 194862 | 42405 | 79506956 |
Device related infection | 15.10 | 9.48 | 139 | 194888 | 34155 | 79515206 |
Injury | 15.09 | 9.48 | 270 | 194757 | 77226 | 79472135 |
Neurotransmitter level altered | 15.08 | 9.48 | 4 | 195023 | 10 | 79549351 |
Injection site joint erythema | 15.05 | 9.48 | 3 | 195024 | 0 | 79549361 |
Inflammatory marker increased | 15.02 | 9.48 | 59 | 194968 | 10681 | 79538680 |
Respiratory arrest | 15.00 | 9.48 | 81 | 194946 | 57469 | 79491892 |
Proctitis | 14.98 | 9.48 | 42 | 194985 | 6390 | 79542971 |
Plantar fascial fibromatosis | 14.89 | 9.48 | 5 | 195022 | 34 | 79549327 |
Anal skin tags | 14.85 | 9.48 | 11 | 195016 | 466 | 79548895 |
Rash macular | 14.74 | 9.48 | 121 | 194906 | 28778 | 79520583 |
Anxiety disorder | 14.70 | 9.48 | 32 | 194995 | 4155 | 79545206 |
Liver function test increased | 14.68 | 9.48 | 49 | 194978 | 39724 | 79509637 |
Immunodeficiency | 14.66 | 9.48 | 19 | 195008 | 21749 | 79527612 |
Enterobiasis | 14.65 | 9.48 | 5 | 195022 | 36 | 79549325 |
Factor XIII Inhibition | 14.65 | 9.48 | 5 | 195022 | 36 | 79549325 |
Oral candidiasis | 14.55 | 9.48 | 123 | 194904 | 29505 | 79519856 |
Chronic kidney disease | 14.53 | 9.48 | 235 | 194792 | 65919 | 79483442 |
Botulism | 14.43 | 9.48 | 10 | 195017 | 381 | 79548980 |
Neurotoxicity | 14.42 | 9.48 | 132 | 194895 | 32386 | 79516975 |
Fusarium infection | 14.40 | 9.48 | 20 | 195007 | 1812 | 79547549 |
Skin test positive | 14.36 | 9.48 | 16 | 195011 | 1158 | 79548203 |
Lupus-like syndrome | 14.34 | 9.48 | 8 | 195019 | 13849 | 79535512 |
Disease complication | 14.33 | 9.48 | 35 | 194992 | 4902 | 79544459 |
Renal cancer | 14.27 | 9.48 | 6 | 195021 | 12220 | 79537141 |
Hepatotoxicity | 14.26 | 9.48 | 190 | 194837 | 51162 | 79498199 |
Vulvovaginal pain | 14.25 | 9.48 | 22 | 195005 | 2193 | 79547168 |
Rectal tenesmus | 14.25 | 9.48 | 19 | 195008 | 1656 | 79547705 |
Ankylosing spondylitis | 14.22 | 9.48 | 6 | 195021 | 12199 | 79537162 |
Kounis syndrome | 14.22 | 9.48 | 32 | 194995 | 4250 | 79545111 |
Coeliac disease | 14.19 | 9.48 | 5 | 195022 | 11346 | 79538015 |
Stomatococcal infection | 14.16 | 9.48 | 9 | 195018 | 296 | 79549065 |
Retinitis viral | 14.14 | 9.48 | 7 | 195020 | 140 | 79549221 |
Blood creatine increased | 14.09 | 9.48 | 53 | 194974 | 9402 | 79539959 |
Rhabdomyolysis | 14.08 | 9.48 | 341 | 194686 | 102790 | 79446571 |
Pseudomonal sepsis | 14.07 | 9.48 | 40 | 194987 | 6134 | 79543227 |
Pain in extremity | 14.05 | 9.48 | 1054 | 193973 | 363484 | 79185877 |
Peripheral venous disease | 14.01 | 9.48 | 11 | 195016 | 15898 | 79533463 |
Myelosuppression | 13.96 | 9.48 | 51 | 194976 | 40245 | 79509116 |
Treatment noncompliance | 13.94 | 9.48 | 73 | 194954 | 52195 | 79497166 |
Incorrect dose administered | 13.93 | 9.48 | 120 | 194907 | 76510 | 79472851 |
Deficiency of bile secretion | 13.88 | 9.48 | 5 | 195022 | 43 | 79549318 |
Epilepsy | 13.87 | 9.48 | 157 | 194870 | 40703 | 79508658 |
Endocarditis | 13.85 | 9.48 | 57 | 194970 | 10540 | 79538821 |
Eye infection fungal | 13.84 | 9.48 | 11 | 195016 | 518 | 79548843 |
Glycosylated haemoglobin increased | 13.83 | 9.48 | 16 | 195011 | 19244 | 79530117 |
Drain placement | 13.79 | 9.48 | 7 | 195020 | 148 | 79549213 |
Cataract | 13.79 | 9.48 | 92 | 194935 | 62028 | 79487333 |
Accidental overdose | 13.78 | 9.48 | 50 | 194977 | 39531 | 79509830 |
Activated partial thromboplastin time prolonged | 13.73 | 9.48 | 70 | 194957 | 14158 | 79535203 |
Faecal calprotectin increased | 13.72 | 9.48 | 37 | 194990 | 5504 | 79543857 |
Myocardial ischaemia | 13.65 | 9.48 | 26 | 195001 | 25493 | 79523868 |
Hypersensitivity | 13.62 | 9.48 | 514 | 194513 | 261725 | 79287636 |
Gastric cancer | 13.58 | 9.48 | 4 | 195023 | 10175 | 79539186 |
Probiotic therapy | 13.58 | 9.48 | 7 | 195020 | 153 | 79549208 |
Seroconversion test positive | 13.58 | 9.48 | 5 | 195022 | 46 | 79549315 |
Carcinoembryonic antigen | 13.56 | 9.48 | 6 | 195021 | 92 | 79549269 |
Fungal infection | 13.54 | 9.48 | 159 | 194868 | 41589 | 79507772 |
Scrotal oedema | 13.52 | 9.48 | 18 | 195009 | 1567 | 79547794 |
Fatigue | 13.49 | 9.48 | 2032 | 192995 | 927695 | 78621666 |
Enterocolonic fistula | 13.42 | 9.48 | 7 | 195020 | 157 | 79549204 |
Carbohydrate antigen 15-3 | 13.39 | 9.48 | 6 | 195021 | 95 | 79549266 |
Metabolic disorder | 13.33 | 9.48 | 51 | 194976 | 9119 | 79540242 |
Vaginal infection | 13.31 | 9.48 | 38 | 194989 | 5842 | 79543519 |
Pyuria | 13.27 | 9.48 | 22 | 195005 | 2330 | 79547031 |
Bovine tuberculosis | 13.26 | 9.48 | 7 | 195020 | 161 | 79549200 |
Arterial angioplasty | 13.21 | 9.48 | 5 | 195022 | 50 | 79549311 |
Osteolysis | 13.17 | 9.48 | 32 | 194995 | 4466 | 79544895 |
Rhinalgia | 13.16 | 9.48 | 22 | 195005 | 2345 | 79547016 |
Anorectal discomfort | 13.14 | 9.48 | 28 | 194999 | 3583 | 79545778 |
Neutropenic sepsis | 13.11 | 9.48 | 112 | 194915 | 26952 | 79522409 |
Vaginal flatulence | 13.09 | 9.48 | 23 | 195004 | 2552 | 79546809 |
Increased viscosity of bronchial secretion | 13.05 | 9.48 | 11 | 195016 | 563 | 79548798 |
Type IV hypersensitivity reaction | 13.00 | 9.48 | 30 | 194997 | 4051 | 79545310 |
Exfoliative rash | 12.99 | 9.48 | 29 | 194998 | 3830 | 79545531 |
Loss of consciousness | 12.98 | 9.48 | 312 | 194715 | 167631 | 79381730 |
Aeromonas test positive | 12.98 | 9.48 | 3 | 195024 | 3 | 79549358 |
Arthritis gonococcal | 12.98 | 9.48 | 3 | 195024 | 3 | 79549358 |
Vertebral artery hypoplasia | 12.98 | 9.48 | 3 | 195024 | 3 | 79549358 |
Eyelid oedema | 12.97 | 9.48 | 67 | 194960 | 13620 | 79535741 |
Peritoneal adhesions | 12.92 | 9.48 | 9 | 195018 | 346 | 79549015 |
Needle issue | 12.88 | 9.48 | 8 | 195019 | 13060 | 79536301 |
Peripheral nerve injury | 12.88 | 9.48 | 12 | 195015 | 702 | 79548659 |
Gastrointestinal pain | 12.87 | 9.48 | 53 | 194974 | 9802 | 79539559 |
Grip strength decreased | 12.86 | 9.48 | 21 | 195006 | 21848 | 79527513 |
Haemolytic anaemia | 12.79 | 9.48 | 81 | 194946 | 17739 | 79531622 |
Visual snow syndrome | 12.79 | 9.48 | 5 | 195022 | 55 | 79549306 |
Clostridium colitis | 12.71 | 9.48 | 24 | 195003 | 2815 | 79546546 |
Infrequent bowel movements | 12.71 | 9.48 | 18 | 195009 | 1661 | 79547700 |
Pelvic fracture | 12.70 | 9.48 | 7 | 195020 | 12197 | 79537164 |
Psoas abscess | 12.68 | 9.48 | 14 | 195013 | 1003 | 79548358 |
Angina unstable | 12.68 | 9.48 | 13 | 195014 | 16514 | 79532847 |
Axonal neuropathy | 12.66 | 9.48 | 20 | 195007 | 2034 | 79547327 |
Arthralgia | 12.66 | 9.48 | 1590 | 193437 | 570213 | 78979148 |
Respiratory tract oedema | 12.61 | 9.48 | 13 | 195014 | 861 | 79548500 |
Enterovesical fistula | 12.59 | 9.48 | 15 | 195012 | 1167 | 79548194 |
Purple glove syndrome | 12.56 | 9.48 | 8 | 195019 | 264 | 79549097 |
Acid base balance abnormal | 12.54 | 9.48 | 9 | 195018 | 363 | 79548998 |
Haemorrhage urinary tract | 12.54 | 9.48 | 22 | 195005 | 2439 | 79546922 |
Tremor | 12.52 | 9.48 | 522 | 194505 | 169561 | 79379800 |
Organic brain syndrome | 12.52 | 9.48 | 10 | 195017 | 474 | 79548887 |
Device issue | 12.51 | 9.48 | 30 | 194997 | 27078 | 79522283 |
Facet joint syndrome | 12.48 | 9.48 | 6 | 195021 | 11296 | 79538065 |
Glare | 12.45 | 9.48 | 6 | 195021 | 113 | 79549248 |
Nervousness | 12.45 | 9.48 | 41 | 194986 | 33374 | 79515987 |
Autonomic neuropathy | 12.44 | 9.48 | 19 | 195008 | 1876 | 79547485 |
Lactic acidosis | 12.42 | 9.48 | 111 | 194916 | 70248 | 79479113 |
Osteopenia | 12.40 | 9.48 | 16 | 195011 | 18348 | 79531013 |
Performance status decreased | 12.40 | 9.48 | 38 | 194989 | 6075 | 79543286 |
Stenotrophomonas test positive | 12.34 | 9.48 | 9 | 195018 | 372 | 79548989 |
Drug level below therapeutic | 12.33 | 9.48 | 52 | 194975 | 9718 | 79539643 |
Arthritis | 12.33 | 9.48 | 202 | 194825 | 114678 | 79434683 |
Dehydration | 12.30 | 9.48 | 733 | 194294 | 247454 | 79301907 |
Colorectal cancer | 12.29 | 9.48 | 3 | 195024 | 8644 | 79540717 |
Left ventricular hypertrophy | 12.26 | 9.48 | 6 | 195021 | 11185 | 79538176 |
Faecal volume decreased | 12.25 | 9.48 | 7 | 195020 | 189 | 79549172 |
Herpes zoster meningoencephalitis | 12.23 | 9.48 | 12 | 195015 | 749 | 79548612 |
Product storage error | 12.18 | 9.48 | 13 | 195014 | 16213 | 79533148 |
Organ failure | 12.14 | 9.48 | 29 | 194998 | 4004 | 79545357 |
Muscle discomfort | 12.12 | 9.48 | 8 | 195019 | 281 | 79549080 |
Pulmonary fibrosis | 12.11 | 9.48 | 61 | 194966 | 44051 | 79505310 |
Vision blurred | 12.09 | 9.48 | 342 | 194685 | 105556 | 79443805 |
Gastrointestinal haemorrhage | 12.09 | 9.48 | 272 | 194755 | 147447 | 79401914 |
Product complaint | 12.05 | 9.48 | 9 | 195018 | 13340 | 79536021 |
Cardiac murmur | 12.03 | 9.48 | 73 | 194954 | 15751 | 79533610 |
Cerebellar syndrome | 12.00 | 9.48 | 35 | 194992 | 5445 | 79543916 |
Clostridium bacteraemia | 11.99 | 9.48 | 9 | 195018 | 389 | 79548972 |
Ligament rupture | 11.99 | 9.48 | 26 | 195001 | 3368 | 79545993 |
Pain | 11.99 | 9.48 | 1523 | 193504 | 702279 | 78847082 |
Neuropsychiatric symptoms | 11.96 | 9.48 | 16 | 195011 | 1399 | 79547962 |
Renal pain | 11.94 | 9.48 | 46 | 194981 | 8250 | 79541111 |
Overgrowth bacterial | 11.92 | 9.48 | 7 | 195020 | 199 | 79549162 |
Progressive multifocal leukoencephalopathy | 11.91 | 9.48 | 20 | 195007 | 20580 | 79528781 |
Colour blindness acquired | 11.90 | 9.48 | 6 | 195021 | 125 | 79549236 |
Cryptitis | 11.90 | 9.48 | 8 | 195019 | 290 | 79549071 |
Tonsillar haemorrhage | 11.90 | 9.48 | 8 | 195019 | 290 | 79549071 |
Apoptosis | 11.89 | 9.48 | 10 | 195017 | 510 | 79548851 |
Therapeutic response unexpected | 11.87 | 9.48 | 19 | 195008 | 19927 | 79529434 |
Renal abscess | 11.86 | 9.48 | 14 | 195013 | 1079 | 79548282 |
Abortion spontaneous | 11.84 | 9.48 | 35 | 194992 | 29472 | 79519889 |
Skin exfoliation | 11.83 | 9.48 | 195 | 194832 | 54905 | 79494456 |
Mitochondrial enzyme deficiency | 11.81 | 9.48 | 4 | 195023 | 28 | 79549333 |
Basophil count abnormal | 11.81 | 9.48 | 4 | 195023 | 28 | 79549333 |
Bone cyst | 11.79 | 9.48 | 26 | 195001 | 3407 | 79545954 |
Penile blister | 11.78 | 9.48 | 5 | 195022 | 69 | 79549292 |
Rhinorrhoea | 11.75 | 9.48 | 124 | 194903 | 75950 | 79473411 |
Throat tightness | 11.73 | 9.48 | 112 | 194915 | 27795 | 79521566 |
Vascular access site pain | 11.73 | 9.48 | 6 | 195021 | 129 | 79549232 |
Groin pain | 11.69 | 9.48 | 63 | 194964 | 13017 | 79536344 |
Painful respiration | 11.68 | 9.48 | 26 | 195001 | 3427 | 79545934 |
Full blood count abnormal | 11.67 | 9.48 | 55 | 194972 | 40419 | 79508942 |
Device leakage | 11.63 | 9.48 | 6 | 195021 | 10850 | 79538511 |
Periorbital oedema | 11.62 | 9.48 | 46 | 194981 | 8356 | 79541005 |
Cognitive disorder | 11.62 | 9.48 | 112 | 194915 | 69814 | 79479547 |
Inflammation | 11.62 | 9.48 | 306 | 194721 | 93447 | 79455914 |
Resuscitation | 11.62 | 9.48 | 21 | 195006 | 2383 | 79546978 |
Prostate cancer | 11.59 | 9.48 | 42 | 194985 | 33226 | 79516135 |
Colonic fistula | 11.56 | 9.48 | 11 | 195016 | 661 | 79548700 |
Bacteraemia | 11.54 | 9.48 | 127 | 194900 | 32697 | 79516664 |
Peripheral arterial occlusive disease | 11.48 | 9.48 | 3 | 195024 | 8255 | 79541106 |
Ototoxicity | 11.47 | 9.48 | 25 | 195002 | 3249 | 79546112 |
Miosis | 11.46 | 9.48 | 13 | 195014 | 15776 | 79533585 |
Microbiology test abnormal | 11.45 | 9.48 | 3 | 195024 | 7 | 79549354 |
Musculoskeletal stiffness | 11.45 | 9.48 | 333 | 194694 | 174675 | 79374686 |
Tooth fracture | 11.45 | 9.48 | 7 | 195020 | 11523 | 79537838 |
Palmar-plantar erythrodysaesthesia syndrome | 11.44 | 9.48 | 42 | 194985 | 33092 | 79516269 |
Bundle branch block left | 11.42 | 9.48 | 7 | 195020 | 11506 | 79537855 |
Creatinine renal clearance decreased | 11.40 | 9.48 | 18 | 195009 | 18984 | 79530377 |
Penile oedema | 11.40 | 9.48 | 8 | 195019 | 311 | 79549050 |
Large intestinal stenosis | 11.40 | 9.48 | 23 | 195004 | 2833 | 79546528 |
Burning mouth syndrome | 11.36 | 9.48 | 10 | 195017 | 543 | 79548818 |
Microvillous inclusion disease | 11.35 | 9.48 | 7 | 195020 | 218 | 79549143 |
Complex regional pain syndrome | 11.34 | 9.48 | 19 | 195008 | 2029 | 79547332 |
Mucous stools | 11.33 | 9.48 | 33 | 194994 | 5129 | 79544232 |
Rash papular | 11.31 | 9.48 | 92 | 194935 | 21824 | 79527537 |
Lower limb fracture | 11.27 | 9.48 | 25 | 195002 | 23190 | 79526171 |
Candida osteomyelitis | 11.25 | 9.48 | 4 | 195023 | 33 | 79549328 |
Injection site haemorrhage | 11.23 | 9.48 | 33 | 194994 | 27837 | 79521524 |
Gastrointestinal disorder | 11.18 | 9.48 | 221 | 194806 | 121984 | 79427377 |
Chromaturia | 11.16 | 9.48 | 104 | 194923 | 25642 | 79523719 |
Injection site urticaria | 11.13 | 9.48 | 9 | 195018 | 12817 | 79536544 |
Hyperchlorhydria | 11.13 | 9.48 | 19 | 195008 | 2060 | 79547301 |
Joint instability | 11.09 | 9.48 | 16 | 195011 | 1502 | 79547859 |
Arrhythmia | 11.07 | 9.48 | 211 | 194816 | 61061 | 79488300 |
Hepatic steatosis | 11.05 | 9.48 | 141 | 194886 | 37597 | 79511764 |
Burnout syndrome | 11.03 | 9.48 | 8 | 195019 | 328 | 79549033 |
Parosmia | 11.02 | 9.48 | 40 | 194987 | 6974 | 79542387 |
Pruritus | 10.98 | 9.48 | 1114 | 193913 | 393534 | 79155827 |
Blood bilirubin increased | 10.93 | 9.48 | 225 | 194802 | 66007 | 79483354 |
Urine odour abnormal | 10.92 | 9.48 | 37 | 194990 | 6236 | 79543125 |
Roseola | 10.91 | 9.48 | 3 | 195024 | 9 | 79549352 |
Respiratory tract inflammation | 10.91 | 9.48 | 12 | 195015 | 856 | 79548505 |
Internal haemorrhage | 10.86 | 9.48 | 4 | 195023 | 8829 | 79540532 |
Malignant melanoma | 10.85 | 9.48 | 12 | 195015 | 14729 | 79534632 |
Penile erythema | 10.84 | 9.48 | 6 | 195021 | 152 | 79549209 |
Actinic keratosis | 10.84 | 9.48 | 36 | 194991 | 6006 | 79543355 |
Calculus bladder | 10.82 | 9.48 | 15 | 195012 | 1357 | 79548004 |
Encephalopathy | 10.81 | 9.48 | 228 | 194799 | 67169 | 79482192 |
Injection site rash | 10.78 | 9.48 | 17 | 195010 | 17937 | 79531424 |
Cardiac failure chronic | 10.72 | 9.48 | 7 | 195020 | 11128 | 79538233 |
Tongue disorder | 10.71 | 9.48 | 11 | 195016 | 13964 | 79535397 |
Sense of oppression | 10.71 | 9.48 | 16 | 195011 | 1550 | 79547811 |
Nephropathy toxic | 10.69 | 9.48 | 86 | 194941 | 20333 | 79529028 |
Tongue coated | 10.68 | 9.48 | 15 | 195012 | 1374 | 79547987 |
Metatarsal excision | 10.67 | 9.48 | 3 | 195024 | 10 | 79549351 |
Orchitis noninfective | 10.67 | 9.48 | 3 | 195024 | 10 | 79549351 |
Occupational exposure to air contaminants | 10.63 | 9.48 | 6 | 195021 | 158 | 79549203 |
Joint injury | 10.63 | 9.48 | 40 | 194987 | 31295 | 79518066 |
Hypercreatininaemia | 10.62 | 9.48 | 13 | 195014 | 1040 | 79548321 |
Hypoxia | 10.60 | 9.48 | 183 | 194844 | 103060 | 79446301 |
Procalcitonin increased | 10.59 | 9.48 | 23 | 195004 | 2983 | 79546378 |
Glomerular filtration rate decreased | 10.58 | 9.48 | 25 | 195002 | 22677 | 79526684 |
Keratitis bacterial | 10.57 | 9.48 | 6 | 195021 | 160 | 79549201 |
Colonic abscess | 10.51 | 9.48 | 15 | 195012 | 1394 | 79547967 |
Product dose omission in error | 10.50 | 9.48 | 3 | 195024 | 7785 | 79541576 |
Epicondylitis | 10.49 | 9.48 | 19 | 195008 | 2159 | 79547202 |
Herpes simplex colitis | 10.48 | 9.48 | 4 | 195023 | 41 | 79549320 |
Multiple-drug resistance | 10.44 | 9.48 | 46 | 194981 | 8762 | 79540599 |
Petechiae | 10.43 | 9.48 | 86 | 194941 | 20479 | 79528882 |
Lip swelling | 10.40 | 9.48 | 149 | 194878 | 40762 | 79508599 |
Prolapse | 10.40 | 9.48 | 4 | 195023 | 42 | 79549319 |
Urinary tract infection pseudomonal | 10.39 | 9.48 | 17 | 195010 | 1781 | 79547580 |
Pleural neoplasm | 10.38 | 9.48 | 8 | 195019 | 360 | 79549001 |
Culture stool positive | 10.37 | 9.48 | 10 | 195017 | 611 | 79548750 |
Bladder cancer | 10.35 | 9.48 | 20 | 195007 | 19506 | 79529855 |
Perineal pain | 10.34 | 9.48 | 13 | 195014 | 1069 | 79548292 |
Diabetes mellitus inadequate control | 10.31 | 9.48 | 28 | 194999 | 24236 | 79525125 |
Dyslipidaemia | 10.30 | 9.48 | 8 | 195019 | 11625 | 79537736 |
Hypoacusis | 10.30 | 9.48 | 116 | 194911 | 30034 | 79519327 |
Biopsy colon abnormal | 10.29 | 9.48 | 5 | 195022 | 96 | 79549265 |
Paranasal sinus discomfort | 10.28 | 9.48 | 29 | 194998 | 4427 | 79544934 |
Gynaecomastia | 10.28 | 9.48 | 3 | 195024 | 7678 | 79541683 |
Papilloma | 10.26 | 9.48 | 8 | 195019 | 366 | 79548995 |
Infective exacerbation of bronchiectasis | 10.25 | 9.48 | 11 | 195016 | 763 | 79548598 |
Aural polyp | 10.24 | 9.48 | 5 | 195022 | 97 | 79549264 |
Incision site discharge | 10.23 | 9.48 | 4 | 195023 | 44 | 79549317 |
Flavobacterium infection | 10.19 | 9.48 | 5 | 195022 | 98 | 79549263 |
Cholecystitis acute | 10.19 | 9.48 | 62 | 194965 | 13389 | 79535972 |
Urethral pain | 10.16 | 9.48 | 9 | 195018 | 493 | 79548868 |
Rebound acid hypersecretion | 10.15 | 9.48 | 5 | 195022 | 99 | 79549262 |
Neuroleptic malignant syndrome | 10.14 | 9.48 | 34 | 194993 | 27525 | 79521836 |
Left ventricular dysfunction | 10.12 | 9.48 | 20 | 195007 | 19341 | 79530020 |
Candida test positive | 10.11 | 9.48 | 13 | 195014 | 1093 | 79548268 |
Urethral stenosis | 10.11 | 9.48 | 13 | 195014 | 1093 | 79548268 |
Distal intestinal obstruction syndrome | 10.10 | 9.48 | 11 | 195016 | 776 | 79548585 |
Peritonitis | 10.10 | 9.48 | 109 | 194918 | 27927 | 79521434 |
Subacute cutaneous lupus erythematosus | 10.07 | 9.48 | 25 | 195002 | 3536 | 79545825 |
Convulsive threshold lowered | 10.06 | 9.48 | 12 | 195015 | 935 | 79548426 |
Presyncope | 10.04 | 9.48 | 59 | 194968 | 40995 | 79508366 |
Cardiac discomfort | 10.03 | 9.48 | 14 | 195013 | 1274 | 79548087 |
Diarrhoea haemorrhagic | 10.03 | 9.48 | 61 | 194966 | 13173 | 79536188 |
Pseudomonas test positive | 10.02 | 9.48 | 17 | 195010 | 1835 | 79547526 |
Infection | 9.99 | 9.48 | 486 | 194541 | 241226 | 79308135 |
White blood cells urine | 9.99 | 9.48 | 9 | 195018 | 504 | 79548857 |
Angiopathy | 9.98 | 9.48 | 39 | 194988 | 7043 | 79542318 |
Administration site swelling | 9.96 | 9.48 | 9 | 195018 | 506 | 79548855 |
Testicular pain | 9.93 | 9.48 | 18 | 195009 | 2047 | 79547314 |
Injection site streaking | 9.92 | 9.48 | 4 | 195023 | 48 | 79549313 |
Blood calcium decreased | 9.92 | 9.48 | 42 | 194985 | 31777 | 79517584 |
Lung disorder | 9.89 | 9.48 | 138 | 194889 | 80419 | 79468942 |
Aphthous ulcer | 9.88 | 9.48 | 73 | 194954 | 16816 | 79532545 |
Vipoma | 9.88 | 9.48 | 3 | 195024 | 14 | 79549347 |
Finger deformity | 9.86 | 9.48 | 3 | 195024 | 7471 | 79541890 |
Ligament injury | 9.85 | 9.48 | 13 | 195014 | 1122 | 79548239 |
Sitting disability | 9.84 | 9.48 | 8 | 195019 | 389 | 79548972 |
Hepatic amoebiasis | 9.84 | 9.48 | 5 | 195022 | 106 | 79549255 |
Genital pain | 9.79 | 9.48 | 11 | 195016 | 803 | 79548558 |
Platelet count decreased | 9.78 | 9.48 | 383 | 194644 | 194281 | 79355080 |
Genital paraesthesia | 9.78 | 9.48 | 4 | 195023 | 50 | 79549311 |
Adjustment disorder with depressed mood | 9.76 | 9.48 | 5 | 195022 | 9081 | 79540280 |
Vulvovaginal candidiasis | 9.74 | 9.48 | 20 | 195007 | 2494 | 79546867 |
Labelled drug-drug interaction medication error | 9.73 | 9.48 | 107 | 194920 | 27543 | 79521818 |
Onychomycosis | 9.73 | 9.48 | 4 | 195023 | 8257 | 79541104 |
Lower respiratory tract infection | 9.72 | 9.48 | 241 | 194786 | 128979 | 79420382 |
Suspected suicide | 9.72 | 9.48 | 7 | 195020 | 10569 | 79538792 |
Blood catecholamines decreased | 9.71 | 9.48 | 3 | 195024 | 15 | 79549346 |
Gallbladder rupture | 9.71 | 9.48 | 12 | 195015 | 970 | 79548391 |
Altered state of consciousness | 9.67 | 9.48 | 65 | 194962 | 43757 | 79505604 |
Chills | 9.67 | 9.48 | 482 | 194545 | 159752 | 79389609 |
Gallbladder polyp | 9.63 | 9.48 | 12 | 195015 | 978 | 79548383 |
Post procedural infection | 9.62 | 9.48 | 54 | 194973 | 11330 | 79538031 |
Irritability | 9.61 | 9.48 | 60 | 194967 | 41084 | 79508277 |
Interstitial lung disease | 9.60 | 9.48 | 206 | 194821 | 112394 | 79436967 |
Glomerulonephritis acute | 9.59 | 9.48 | 7 | 195020 | 290 | 79549071 |
Vaginal abscess | 9.58 | 9.48 | 8 | 195019 | 404 | 79548957 |
Wound drainage | 9.57 | 9.48 | 13 | 195014 | 1153 | 79548208 |
Intentional product use issue | 9.56 | 9.48 | 291 | 194736 | 151821 | 79397540 |
Akathisia | 9.54 | 9.48 | 11 | 195016 | 13248 | 79536113 |
Hypercalcaemia | 9.52 | 9.48 | 55 | 194972 | 38375 | 79510986 |
Increased tendency to bruise | 9.52 | 9.48 | 7 | 195020 | 10457 | 79538904 |
None
Source | Code | Description |
---|---|---|
ATC | J01MA02 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE QUINOLONE ANTIBACTERIALS Fluoroquinolones |
ATC | J01RA10 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE COMBINATIONS OF ANTIBACTERIALS Combinations of antibacterials |
ATC | J01RA11 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE COMBINATIONS OF ANTIBACTERIALS Combinations of antibacterials |
ATC | J01RA12 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE COMBINATIONS OF ANTIBACTERIALS Combinations of antibacterials |
ATC | S01AE03 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFECTIVES Fluoroquinolones |
ATC | S02AA15 | SENSORY ORGANS OTOLOGICALS ANTIINFECTIVES Antiinfectives |
ATC | S03AA07 | SENSORY ORGANS OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS ANTIINFECTIVES Antiinfectives |
FDA CS | M0023650 | Quinolones |
FDA CS | M0372253 | Fluoroquinolones |
MeSH PA | D000900 | Anti-Bacterial Agents |
MeSH PA | D000890 | Anti-Infective Agents |
MeSH PA | D000970 | Antineoplastic Agents |
MeSH PA | D065609 | Cytochrome P-450 CYP1A2 Inhibitors |
MeSH PA | D065607 | Cytochrome P-450 Enzyme Inhibitors |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D065606 | Metabolic Side Effects of Drugs and Substances |
MeSH PA | D059005 | Topoisomerase II Inhibitors |
MeSH PA | D059003 | Topoisomerase Inhibitors |
FDA EPC | N0000175937 | Quinolone Antimicrobial |
FDA MoA | N0000182138 | Cytochrome P450 1A2 Inhibitors |
FDA EPC | N0000193223 | Fluoroquinolone Antibacterial |
CHEBI has role | CHEBI:35441 | antiinfective agents |
CHEBI has role | CHEBI:36047 | antibacterial drugs |
CHEBI has role | CHEBI:50750 | inhibitors of type II topoisomerase |
CHEBI has role | CHEBI:53559 | topoisomerase IV inhibitors |
CHEBI has role | CHEBI:33281 | antibiotics |
CHEBI has role | CHEBI:35703 | Xenobiotic |
CHEBI has role | CHEBI:59517 | DNA synthesis inhibitors |
CHEBI has role | CHEBI:78298 | environmental contaminants |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Otitis externa | indication | 3135009 | |
Typhoid fever | indication | 4834000 | DOID:13258 |
Septicemia due to Escherichia coli | indication | 9323009 | |
Prostatitis | indication | 9713002 | DOID:14654 |
Infection due to Pseudomonas aeruginosa | indication | 11218009 | |
Enteric campylobacteriosis | indication | 18081009 | |
Infectious diarrheal disease | indication | 19213003 | DOID:13250 |
Infection of skin AND/OR subcutaneous tissue | indication | 19824006 | |
Acute gonococcal cervicitis | indication | 20943002 | DOID:10615 |
Acute gonococcal urethritis | indication | 29864006 | |
Acute bacterial peritonitis | indication | 31860008 | |
Pneumonia due to Streptococcus | indication | 34020007 | |
Shigellosis | indication | 36188001 | |
Cystitis | indication | 38822007 | DOID:1679 |
Pneumonia due to Pseudomonas | indication | 41381004 | |
Lower respiratory tract infection | indication | 50417007 | |
Pneumonia due to Escherichia coli | indication | 51530003 | |
Bacterial pneumonia | indication | 53084003 | DOID:874 |
Klebsiella cystitis | indication | 60867007 | |
Acute maxillary sinusitis | indication | 68272006 | DOID:2050 |
Haemophilus influenzae pneumonia | indication | 70036007 | |
Infection due to Escherichia coli | indication | 71057007 | |
Rhinoscleroma | indication | 72409005 | DOID:11336 |
Abdominal abscess | indication | 75100008 | |
Acute bacterial sinusitis | indication | 75498004 | |
Infective otitis externa | indication | 86981007 | DOID:9463 |
Infection of bone | indication | 111253001 | |
Infectious disease of abdomen | indication | 128070006 | |
Bacterial conjunctivitis | indication | 128350005 | DOID:9700 |
Infection due to Enterobacteriaceae | indication | 128945009 | |
Bacterial infection due to Klebsiella pneumoniae | indication | 186435004 | |
Acute Moraxella catarrhalis bronchitis | indication | 195722003 | |
Proteus pneumonia | indication | 195888009 | |
Malignant otitis externa due to Pseudomonas aeruginosa | indication | 232230009 | |
Acute bacterial bronchitis | indication | 233598009 | |
Infective cystitis | indication | 236620008 | |
Chancroid | indication | 266143009 | DOID:13778 |
Escherichia coli urinary tract infection | indication | 301011002 | |
Proteus urinary tract infection | indication | 301012009 | |
Streptococcus pyogenes infection | indication | 302809008 | |
Bacterial urinary infection | indication | 312124009 | |
Infective otitis media | indication | 312218008 | |
Infectious disorder of joint | indication | 363162000 | |
Infection due to Staphylococcus aureus | indication | 406602003 | |
Anthrax | indication | 409498004 | DOID:7427 |
Acute osteomyelitis | indication | 409780002 | |
Nosocomial pneumonia | indication | 425464007 | |
Urinary tract infection caused by Klebsiella | indication | 369001000119100 | |
Skin and Skin Structure Pseudomonas Aeruginosa Infection | indication | ||
Complicated UTI with Pseudomonas Aeruginosa | indication | ||
Staphylococcus Epidermidis Urinary Tract Infection | indication | ||
Pseudomonas Aeruginosa Joint Infection | indication | ||
Complicated Proteus UTI | indication | ||
Skin and Skin Structure Providencia Infection | indication | ||
Complicated Bacterial Peritonitis | indication | ||
Staphylococcus Saprophyticus Urinary Tract Infection | indication | ||
Haemophilus Parainfluenzae Pneumonia | indication | ||
Enterobacter Pneumonia | indication | ||
Skin and Skin Structure Citrobacter Infection | indication | ||
Moraxella Catarrhalis Chronic Bronchitis | indication | ||
Diarrhea due to E. Coli | indication | ||
Klebsiella Nosocomial Pneumonia | indication | ||
Citrobacter Urinary Tract Infection | indication | ||
Enterococcus Urinary Tract Infection | indication | ||
Serratia Joint Infection | indication | ||
Skin and Skin Structure Proteus Infection | indication | ||
EnterobacterJoint Infection | indication | ||
Enterobacter Osteomyelitis | indication | ||
Nosocomial Pneumonia due to Haemophilus Influenzae | indication | ||
Complicated Bacteroides Peritonitis | indication | ||
Complicated E. Coli Peritonitis | indication | ||
Morganella Morganii Urinary Tract Infection | indication | ||
Bacterial Corneal Ulcer Infection | indication | ||
E. Coli Cystitis | indication | ||
Staphylococcus Aureus Otitis Externa | indication | ||
Staphylococcus Cystitis | indication | ||
Chronic Bacterial Prostatitis | indication | ||
Pseudomonas Aeruginosa Urinary Tract Infection | indication | ||
Gram-Negative Aerobic Bacillary Pneumonia | indication | ||
Serratia Osteomyelitis | indication | ||
Staphylococcus Epidermidis Skin and Skin Structure Infection | indication | ||
Enterococcus Complicated UTI | indication | ||
Providencia Urinary Tract Infection | indication | ||
Complicated Klebsiella Peritonitis | indication | ||
Skin and Skin Structure Serratia Infection | indication | ||
Proteus Prostatitis | indication | ||
E. Coli Pyelonephritis | indication | ||
Skin and Skin Structure Morganella Morganii Infection | indication | ||
Serratia Urinary Tract Infection | indication | ||
Pseudomonas Aeruginosa Osteomyelitis | indication | ||
Inhalational anthrax | off-label use | 11389007 | |
Traveler's diarrhea | off-label use | 11840006 | |
Salmonella septicemia | off-label use | 49786009 | |
Cutaneous anthrax | off-label use | 84980006 | DOID:7426 |
Gastrointestinal anthrax | off-label use | 111798006 | DOID:13386 |
Diverticulitis of gastrointestinal tract | off-label use | 271366000 | |
Ventilator-acquired pneumonia | off-label use | 429271009 | |
Diabetic Foot Infection | off-label use | ||
Prevention of Meningococcal Meningitis | off-label use | ||
Achilles tendinitis | contraindication | 11654001 | |
Lowered convulsive threshold | contraindication | 19260006 | |
Torsades de pointes | contraindication | 31722008 | |
Transplantation of heart | contraindication | 32413006 | |
Tendinitis | contraindication | 34840004 | DOID:971 |
Hypokalemia | contraindication | 43339004 | |
Transplant of kidney | contraindication | 70536003 | |
Epilepsy | contraindication | 84757009 | DOID:1826 |
Transplant of lung | contraindication | 88039007 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Myasthenia gravis | contraindication | 91637004 | DOID:437 |
Prolonged QT interval | contraindication | 111975006 | |
Superimposed infection | contraindication | 193198003 | |
Peripheral nerve disease | contraindication | 302226006 | |
Viral ear infection | contraindication | 312137007 | |
Pseudomembranous enterocolitis | contraindication | 397683000 | |
Traumatic rupture of tendon | contraindication | 415749005 | |
Congenital long QT syndrome | contraindication | 442917000 | |
Shoulder Tendonitis | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 6.12 | acidic |
pKa2 | 8.54 | Basic |
pKa3 | 1.37 | Basic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
0.3%;0.1% | CIPRODEX | NOVARTIS | N021537 | July 18, 2003 | RX | SUSPENSION/DROPS | OTIC | 8846650 | June 4, 2025 | TREATMENT OF ACUTE OTITIS MEDIA |
6% (60MG/ML) | OTIPRIO | ALK ABELLO | N207986 | Dec. 10, 2015 | DISCN | INJECTABLE, SUSPENSION | OTIC | 9205048 | April 21, 2029 | TREATMENT OF PEDIATRIC PATIENTS WITH OTITIS MEDIA WITH EFFUSION UNDERGOING TYMPANOSTOMY TUBE PLACEMENT |
6% (60MG/ML) | OTIPRIO | ALK ABELLO | N207986 | Dec. 10, 2015 | DISCN | INJECTABLE, SUSPENSION | OTIC | 9603796 | April 21, 2029 | THE TREATMENT OF ACUTE OTITIS EXTERNA IN PATIENTS 6 MONTHS OF AGE AND OLDER DUE TO PSEUDOMONAS AERUGINOSA AND STAPHYLOCOCCUS AUREUS |
EQ 0.3% BASE;0.025% | OTOVEL | LABORATORIOS SALVAT | N208251 | April 29, 2016 | RX | SOLUTION/DROPS | OTIC | 8932610 | March 24, 2030 | TREATMENT OF ACUTE OTITIS MEDIA |
6% (60MG/ML) | OTIPRIO | ALK ABELLO | N207986 | Dec. 10, 2015 | DISCN | INJECTABLE, SUSPENSION | OTIC | 8318817 | April 27, 2030 | TREATMENT OF OTIC INFECTION OR INFLAMMATION |
6% (60MG/ML) | OTIPRIO | ALK ABELLO | N207986 | Dec. 10, 2015 | DISCN | INJECTABLE, SUSPENSION | OTIC | 11040004 | Nov. 12, 2037 | THE TREATMENT OF ACUTE OTITIS EXTERNA IN PATIENTS 6 MONTHS OF AGE AND OLDER DUE TO PSEUDOMONAS AERUGINOSA AND STAPHYLOCOCCUS AUREUS |
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase II | Enzyme | EC50 | 7.52 | CHEMBL | |||||
DNA gyrase subunit A | Enzyme | INHIBITOR | IC50 | 5.75 | WOMBAT-PK | CHEMBL | |||
DNA topoisomerase 4 subunit A | Enzyme | IC50 | 5.66 | WOMBAT-PK | |||||
DNA topoisomerase 4 subunit A | Enzyme | INHIBITOR | IC50 | 6 | WOMBAT-PK | ||||
DNA gyrase subunit A | Enzyme | IC50 | 6.20 | WOMBAT-PK | |||||
Histamine H3 receptor | GPCR | Ki | 9.18 | CHEMBL | |||||
GABA-A receptor; anion channel | Ion channel | IC50 | 6.39 | CHEMBL | |||||
DNA topoisomerase 4 subunit A | Enzyme | IC50 | 5.60 | WOMBAT-PK | |||||
Multidrug resistance protein mdtK | Unclassified | Kd | 4.04 | CHEMBL |
ID | Source |
---|---|
4019307 | VUID |
N0000147503 | NUI |
D00186 | KEGG_DRUG |
86393-32-0 | SECONDARY_CAS_RN |
235851 | RXNORM |
4019306 | VANDF |
4019307 | VANDF |
C0008809 | UMLSCUI |
CHEBI:100241 | CHEBI |
CPF | PDB_CHEM_ID |
CHEMBL8 | ChEMBL_ID |
DB00537 | DRUGBANK_ID |
CHEMBL1202 | ChEMBL_ID |
D002939 | MESH_DESCRIPTOR_UI |
2764 | PUBCHEM_CID |
10902 | IUPHAR_LIGAND_ID |
5446 | INN_ID |
97867-33-9 | SECONDARY_CAS_RN |
5E8K9I0O4U | UNII |
31644 | MMSL |
4451 | MMSL |
4452 | MMSL |
46904 | MMSL |
76342 | MMSL |
d00011 | MMSL |
002882 | NDDF |
003577 | NDDF |
004125 | NDDF |
20450009 | SNOMEDCT_US |
372840008 | SNOMEDCT_US |
428384006 | SNOMEDCT_US |
7577004 | SNOMEDCT_US |
CHEMBL1077975 | ChEMBL_ID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Ciloxan | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0065-0656 | SOLUTION/ DROPS | 3 mg | OPHTHALMIC | NDA | 21 sections |
Ciloxan | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0065-0656 | SOLUTION/ DROPS | 3 mg | OPHTHALMIC | NDA | 21 sections |
CIPROHC | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0065-8531 | SUSPENSION | 2 mg | AURICULAR (OTIC) | NDA | 16 sections |
CIPROHC | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0065-8531 | SUSPENSION | 2 mg | AURICULAR (OTIC) | NDA | 16 sections |
CIPRODEX | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0078-0799 | SUSPENSION/ DROPS | 3 mg | AURICULAR (OTIC) | NDA | 28 sections |
CIPRODEX | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0078-0799 | SUSPENSION/ DROPS | 3 mg | AURICULAR (OTIC) | NDA | 28 sections |
CIPRODEX | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0078-0799 | SUSPENSION/ DROPS | 3 mg | AURICULAR (OTIC) | NDA | 28 sections |
CILOXAN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0078-0841 | OINTMENT | 3 mg | OPHTHALMIC | NDA | 20 sections |
CILOXAN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0078-0841 | OINTMENT | 3 mg | OPHTHALMIC | NDA | 20 sections |
CILOXAN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0078-0841 | OINTMENT | 3 mg | OPHTHALMIC | NDA | 20 sections |
CIPROHC | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0078-0855 | SUSPENSION/ DROPS | 2 mg | AURICULAR (OTIC) | NDA | 16 sections |
CIPROHC | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0078-0855 | SUSPENSION/ DROPS | 2 mg | AURICULAR (OTIC) | NDA | 16 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9927 | TABLET, FILM COATED | 250 mg | ORAL | ANDA | 30 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9927 | TABLET, FILM COATED | 250 mg | ORAL | ANDA | 30 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9928 | TABLET, FILM COATED | 500 mg | ORAL | ANDA | 30 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9928 | TABLET, FILM COATED | 500 mg | ORAL | ANDA | 30 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9929 | TABLET, FILM COATED | 750 mg | ORAL | ANDA | 30 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9929 | TABLET, FILM COATED | 750 mg | ORAL | ANDA | 30 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0172-5311 | TABLET, FILM COATED | 250 mg | ORAL | ANDA | 29 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0172-5312 | TABLET, FILM COATED | 500 mg | ORAL | ANDA | 29 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0172-5313 | TABLET, FILM COATED | 750 mg | ORAL | ANDA | 29 sections |
OTIPRIO | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0268-8200 | SUSPENSION | 60 mg | INTRATYMPANIC | NDA | 26 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0404-7187 | SOLUTION/ DROPS | 3 mg | OPHTHALMIC | ANDA | 24 sections |
Ciprofloxacin in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-2300 | INJECTION, SOLUTION | 200 mg | INTRAVENOUS | ANDA | 33 sections |
Ciprofloxacin in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-3300 | INJECTION, SOLUTION | 400 mg | INTRAVENOUS | ANDA | 33 sections |
CIPROFLOXACIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-4777 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 34 sections |
CIPROFLOXACIN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-4777 | INJECTION, SOLUTION | 2 mg | INTRAVENOUS | ANDA | 34 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8147 | TABLET, FILM COATED | 500 mg | ORAL | ANDA | 29 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8367 | TABLET, FILM COATED | 500 mg | ORAL | ANDA | 31 sections |
Ciprofloxacin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8367 | TABLET, FILM COATED | 500 mg | ORAL | ANDA | 31 sections |