cilazapril 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
angiotensin-converting enzyme inhibitors 641 88768-40-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cilazapril monohydrobromide
  • cilazapril anhydrous
  • cilazapril
  • inhibace
  • vascace
  • cilazapril monohydrate
  • cilazapril hydrate
One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors) used for hypertension. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat.
  • Molecular weight: 417.51
  • Formula: C22H31N3O5
  • CLOGP: 1.47
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 2
  • TPSA: 99.18
  • ALOGS: -2.59
  • ROTB: 9

Drug dosage:

DoseUnitRoute
2.50 mg O

ADMET properties:

Approvals:

None

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

cilazapril