Stem definition | Drug id | CAS RN |
---|---|---|
diphenylmethyl piperazine derivatives | 581 | 83881-51-0 |
Dose | Unit | Route |
---|---|---|
10 | mg | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.10 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 0.37 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 90 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 8, 1995 | FDA | J AND J CONSUMER INC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Pemphigus | 2890.05 | 10.37 | 3813 | 289059 | 153399 | 55845796 |
Systemic lupus erythematosus | 2579.61 | 10.37 | 3876 | 288996 | 176202 | 55822993 |
Glossodynia | 2475.99 | 10.37 | 3483 | 289389 | 148975 | 55850220 |
Hand deformity | 1832.00 | 10.37 | 2830 | 290042 | 131662 | 55867533 |
Abdominal discomfort | 1721.42 | 10.37 | 4179 | 288693 | 273095 | 55726100 |
Alopecia | 1692.47 | 10.37 | 4300 | 288572 | 289158 | 55710037 |
Wound | 1608.12 | 10.37 | 2714 | 290158 | 136090 | 55863105 |
Swelling | 1590.40 | 10.37 | 3709 | 289163 | 236062 | 55763133 |
Pericarditis | 1371.70 | 10.37 | 2212 | 290660 | 106711 | 55892484 |
Discomfort | 1326.71 | 10.37 | 2526 | 290346 | 139235 | 55859960 |
Contraindicated product administered | 1282.78 | 10.37 | 2926 | 289946 | 183360 | 55815835 |
Anti-cyclic citrullinated peptide antibody positive | 1233.98 | 10.37 | 1997 | 290875 | 96603 | 55902592 |
Hypersensitivity | 1128.93 | 10.37 | 3407 | 289465 | 253001 | 55746194 |
Arthropathy | 1128.71 | 10.37 | 2912 | 289960 | 197363 | 55801832 |
Maternal exposure during pregnancy | 910.17 | 10.37 | 2599 | 290273 | 186954 | 55812241 |
Duodenal ulcer perforation | 869.30 | 10.37 | 1395 | 291477 | 66947 | 55932248 |
Infusion related reaction | 847.08 | 10.37 | 2699 | 290173 | 206232 | 55792963 |
Synovitis | 834.52 | 10.37 | 2273 | 290599 | 159032 | 55840163 |
Helicobacter infection | 823.91 | 10.37 | 1415 | 291457 | 71853 | 55927342 |
Muscle injury | 805.14 | 10.37 | 1169 | 291703 | 51331 | 55947864 |
Folliculitis | 799.59 | 10.37 | 1194 | 291678 | 53785 | 55945410 |
Blister | 775.78 | 10.37 | 1735 | 291137 | 107152 | 55892043 |
Hepatic enzyme increased | 759.31 | 10.37 | 2284 | 290588 | 169100 | 55830095 |
Pain | 753.41 | 10.37 | 5950 | 286922 | 657234 | 55341961 |
Irritable bowel syndrome | 733.05 | 10.37 | 1294 | 291578 | 67164 | 55932031 |
Death | 707.36 | 10.37 | 453 | 292419 | 340973 | 55658222 |
Rheumatoid arthritis | 675.55 | 10.37 | 3834 | 289038 | 378770 | 55620425 |
Product use issue | 624.64 | 10.37 | 2257 | 290615 | 183784 | 55815411 |
Rash | 620.90 | 10.37 | 4535 | 288337 | 488512 | 55510683 |
Rheumatoid factor positive | 597.97 | 10.37 | 1192 | 291680 | 67868 | 55931327 |
Urticaria | 555.82 | 10.37 | 1836 | 291036 | 142840 | 55856355 |
Pruritus | 534.75 | 10.37 | 3137 | 289735 | 313486 | 55685709 |
Sleep disorder due to general medical condition, insomnia type | 533.64 | 10.37 | 872 | 292000 | 42466 | 55956729 |
Lower respiratory tract infection | 529.89 | 10.37 | 1553 | 291319 | 113241 | 55885954 |
Toxicity to various agents | 502.73 | 10.37 | 271 | 292601 | 224293 | 55774902 |
Joint swelling | 500.72 | 10.37 | 2889 | 289983 | 286911 | 55712284 |
Acute kidney injury | 490.62 | 10.37 | 325 | 292547 | 240438 | 55758757 |
Anaemia | 484.80 | 10.37 | 408 | 292464 | 267103 | 55732092 |
Therapeutic product effect decreased | 475.18 | 10.37 | 1942 | 290930 | 167510 | 55831685 |
Sinusitis | 474.78 | 10.37 | 2161 | 290711 | 195420 | 55803775 |
Impaired healing | 467.83 | 10.37 | 1243 | 291629 | 85598 | 55913597 |
Drug intolerance | 461.92 | 10.37 | 2647 | 290225 | 262171 | 55737024 |
Fatigue | 435.26 | 10.37 | 6115 | 286757 | 782437 | 55216758 |
Ill-defined disorder | 428.41 | 10.37 | 1038 | 291834 | 67505 | 55931690 |
Fall | 362.10 | 10.37 | 830 | 292042 | 356680 | 55642515 |
Drug interaction | 359.28 | 10.37 | 337 | 292535 | 209418 | 55789777 |
Rheumatic fever | 348.02 | 10.37 | 575 | 292297 | 28252 | 55970943 |
Completed suicide | 343.67 | 10.37 | 133 | 292739 | 133700 | 55865495 |
Hip arthroplasty | 327.38 | 10.37 | 661 | 292211 | 37962 | 55961233 |
Neutropenia | 315.95 | 10.37 | 218 | 292654 | 157949 | 55841246 |
Hypotension | 314.95 | 10.37 | 511 | 292361 | 249997 | 55749198 |
Swollen joint count increased | 311.80 | 10.37 | 497 | 292375 | 23687 | 55975508 |
Gastrointestinal disorder | 309.60 | 10.37 | 1284 | 291588 | 111418 | 55887777 |
Stomatitis | 293.26 | 10.37 | 1326 | 291546 | 119484 | 55879711 |
Knee arthroplasty | 278.33 | 10.37 | 672 | 292200 | 43587 | 55955608 |
Pneumonia | 256.99 | 10.37 | 1167 | 291705 | 405931 | 55593264 |
Thrombocytopenia | 248.63 | 10.37 | 206 | 292666 | 136018 | 55863177 |
Sepsis | 231.95 | 10.37 | 231 | 292641 | 139609 | 55859586 |
Type 2 diabetes mellitus | 228.53 | 10.37 | 647 | 292225 | 46215 | 55952980 |
Diarrhoea | 225.93 | 10.37 | 2180 | 290692 | 636327 | 55362868 |
Treatment failure | 210.06 | 10.37 | 1562 | 291310 | 168830 | 55830365 |
Hyponatraemia | 198.33 | 10.37 | 145 | 292727 | 101994 | 55897201 |
Febrile neutropenia | 198.33 | 10.37 | 155 | 292717 | 105390 | 55893805 |
Nausea | 195.43 | 10.37 | 2803 | 290069 | 761375 | 55237820 |
Malignant neoplasm progression | 194.08 | 10.37 | 70 | 292802 | 73517 | 55925678 |
Food allergy | 175.42 | 10.37 | 223 | 292649 | 8601 | 55990594 |
Disease progression | 175.22 | 10.37 | 173 | 292699 | 105000 | 55894195 |
Liver injury | 174.82 | 10.37 | 547 | 292325 | 41301 | 55957894 |
Nasopharyngitis | 171.17 | 10.37 | 1830 | 291042 | 219129 | 55780066 |
Pancytopenia | 170.87 | 10.37 | 127 | 292745 | 88588 | 55910607 |
Urinary tract infection | 167.79 | 10.37 | 663 | 292209 | 239850 | 55759345 |
Haemoglobin decreased | 167.08 | 10.37 | 275 | 292597 | 133862 | 55865333 |
Cardiac failure | 166.71 | 10.37 | 111 | 292761 | 81982 | 55917213 |
Blood cholesterol increased | 157.95 | 10.37 | 772 | 292100 | 71807 | 55927388 |
Myocardial infarction | 156.74 | 10.37 | 151 | 292721 | 92719 | 55906476 |
Dehydration | 155.40 | 10.37 | 375 | 292497 | 158450 | 55840745 |
Blood creatinine increased | 152.89 | 10.37 | 116 | 292756 | 80075 | 55919120 |
Atrial fibrillation | 150.36 | 10.37 | 208 | 292664 | 108689 | 55890506 |
Gastrointestinal haemorrhage | 147.20 | 10.37 | 108 | 292764 | 75843 | 55923352 |
Renal impairment | 146.05 | 10.37 | 123 | 292749 | 80590 | 55918605 |
Septic shock | 145.59 | 10.37 | 67 | 292805 | 60768 | 55938427 |
Contusion | 144.62 | 10.37 | 1153 | 291719 | 127277 | 55871918 |
Renal failure | 143.79 | 10.37 | 220 | 292652 | 110280 | 55888915 |
Cardio-respiratory arrest | 143.55 | 10.37 | 54 | 292818 | 55267 | 55943928 |
Vomiting | 143.47 | 10.37 | 1782 | 291090 | 496446 | 55502749 |
Depressed level of consciousness | 143.27 | 10.37 | 57 | 292815 | 56376 | 55942819 |
Cardiac failure congestive | 143.01 | 10.37 | 147 | 292725 | 87573 | 55911622 |
Temperature regulation disorder | 136.44 | 10.37 | 141 | 292731 | 4327 | 55994868 |
Leukopenia | 136.03 | 10.37 | 102 | 292770 | 70838 | 55928357 |
Infection | 135.46 | 10.37 | 1615 | 291257 | 198591 | 55800604 |
Respiratory failure | 133.83 | 10.37 | 179 | 292693 | 94883 | 55904312 |
Asthma | 132.23 | 10.37 | 1022 | 291850 | 111748 | 55887447 |
Weight increased | 127.23 | 10.37 | 1786 | 291086 | 227917 | 55771278 |
Peripheral swelling | 124.41 | 10.37 | 1811 | 291061 | 232915 | 55766280 |
Metabolic acidosis | 124.05 | 10.37 | 29 | 292843 | 40425 | 55958770 |
Platelet count decreased | 120.81 | 10.37 | 231 | 292641 | 106152 | 55893043 |
Multiple organ dysfunction syndrome | 120.37 | 10.37 | 62 | 292810 | 52708 | 55946487 |
Angioedema | 118.21 | 10.37 | 478 | 292394 | 40975 | 55958220 |
Coeliac disease | 117.79 | 10.37 | 201 | 292671 | 10138 | 55989057 |
Intentional product use issue | 117.55 | 10.37 | 905 | 291967 | 98828 | 55900367 |
Coma | 116.67 | 10.37 | 84 | 292788 | 59571 | 55939624 |
Cerebrovascular accident | 114.09 | 10.37 | 214 | 292658 | 99056 | 55900139 |
Hypokalaemia | 110.82 | 10.37 | 201 | 292671 | 94236 | 55904959 |
Interstitial lung disease | 108.18 | 10.37 | 83 | 292789 | 56980 | 55942215 |
Overdose | 106.56 | 10.37 | 246 | 292626 | 105584 | 55893611 |
Cardiac arrest | 105.55 | 10.37 | 179 | 292693 | 86135 | 55913060 |
Seizure | 103.20 | 10.37 | 321 | 292551 | 124798 | 55874397 |
International normalised ratio increased | 101.56 | 10.37 | 51 | 292821 | 43990 | 55955205 |
Pleural effusion | 101.13 | 10.37 | 181 | 292691 | 85299 | 55913896 |
Plasma cell myeloma | 98.90 | 10.37 | 60 | 292812 | 46586 | 55952609 |
White blood cell count decreased | 98.51 | 10.37 | 331 | 292541 | 125659 | 55873536 |
Rhabdomyolysis | 98.49 | 10.37 | 44 | 292828 | 40614 | 55958581 |
Haemorrhage | 97.13 | 10.37 | 90 | 292782 | 56307 | 55942888 |
Intentional overdose | 94.11 | 10.37 | 130 | 292742 | 67987 | 55931208 |
Dermatitis atopic | 91.47 | 10.37 | 159 | 292713 | 8140 | 55991055 |
Chronic spontaneous urticaria | 89.74 | 10.37 | 61 | 292811 | 1026 | 55998169 |
Weight decreased | 89.30 | 10.37 | 811 | 292061 | 239903 | 55759292 |
Hypoglycaemia | 88.19 | 10.37 | 96 | 292776 | 55719 | 55943476 |
Asthenia | 87.83 | 10.37 | 1256 | 291616 | 341717 | 55657478 |
Wheezing | 86.27 | 10.37 | 677 | 292195 | 74349 | 55924846 |
Lactic acidosis | 84.45 | 10.37 | 39 | 292833 | 35307 | 55963888 |
Psoriatic arthropathy | 84.10 | 10.37 | 666 | 292206 | 73342 | 55925853 |
Hyperkalaemia | 83.16 | 10.37 | 85 | 292787 | 50780 | 55948415 |
Pneumonia aspiration | 81.83 | 10.37 | 33 | 292839 | 32378 | 55966817 |
Oedema peripheral | 81.29 | 10.37 | 539 | 292333 | 170715 | 55828480 |
Premature delivery | 79.85 | 10.37 | 21 | 292851 | 27039 | 55972156 |
Bone marrow failure | 79.67 | 10.37 | 24 | 292848 | 28262 | 55970933 |
Night sweats | 78.90 | 10.37 | 423 | 292449 | 40790 | 55958405 |
Macular degeneration | 78.80 | 10.37 | 247 | 292625 | 18661 | 55980534 |
Herpes zoster | 78.34 | 10.37 | 174 | 292698 | 75715 | 55923480 |
Drug resistance | 78.15 | 10.37 | 8 | 292864 | 20534 | 55978661 |
Drug abuse | 77.45 | 10.37 | 146 | 292726 | 67464 | 55931731 |
Liver function test abnormal | 77.33 | 10.37 | 74 | 292798 | 45597 | 55953598 |
Pain in extremity | 76.90 | 10.37 | 1087 | 291785 | 296344 | 55702851 |
Hypercalcaemia | 74.46 | 10.37 | 20 | 292852 | 25391 | 55973804 |
Mucosal inflammation | 74.09 | 10.37 | 68 | 292804 | 42742 | 55956453 |
Confusional state | 73.22 | 10.37 | 1504 | 291368 | 206651 | 55792544 |
Muscle spasticity | 72.64 | 10.37 | 249 | 292623 | 19711 | 55979484 |
Loss of consciousness | 71.42 | 10.37 | 309 | 292563 | 109040 | 55890155 |
Ear pain | 71.09 | 10.37 | 334 | 292538 | 30556 | 55968639 |
Injury | 70.98 | 10.37 | 544 | 292328 | 59307 | 55939888 |
Skin ulcer | 70.85 | 10.37 | 58 | 292814 | 38550 | 55960645 |
Cytomegalovirus infection | 69.70 | 10.37 | 9 | 292863 | 19287 | 55979908 |
Chronic kidney disease | 69.07 | 10.37 | 70 | 292802 | 41986 | 55957209 |
Electric shock | 68.69 | 10.37 | 52 | 292820 | 1043 | 55998152 |
Constipation | 67.83 | 10.37 | 697 | 292175 | 201246 | 55797949 |
Cellulitis | 67.82 | 10.37 | 184 | 292688 | 74765 | 55924430 |
Alanine aminotransferase increased | 65.96 | 10.37 | 257 | 292615 | 93405 | 55905790 |
Drug ineffective | 64.55 | 10.37 | 5581 | 287291 | 913408 | 55085787 |
Pulmonary oedema | 64.43 | 10.37 | 104 | 292768 | 51039 | 55948156 |
Prescribed overdose | 64.27 | 10.37 | 258 | 292614 | 22038 | 55977157 |
Shock | 63.85 | 10.37 | 17 | 292855 | 21711 | 55977484 |
Hepatic function abnormal | 63.31 | 10.37 | 52 | 292820 | 34506 | 55964689 |
Drug level increased | 63.25 | 10.37 | 15 | 292857 | 20710 | 55978485 |
Crystal urine present | 63.14 | 10.37 | 58 | 292814 | 1535 | 55997660 |
Decreased appetite | 62.52 | 10.37 | 785 | 292087 | 218446 | 55780749 |
Femur fracture | 61.62 | 10.37 | 68 | 292804 | 39227 | 55959968 |
Respiratory arrest | 61.36 | 10.37 | 42 | 292830 | 30583 | 55968612 |
Acute myeloid leukaemia | 61.10 | 10.37 | 8 | 292864 | 16964 | 55982231 |
Melaena | 60.51 | 10.37 | 36 | 292836 | 28254 | 55970941 |
Altered state of consciousness | 60.51 | 10.37 | 22 | 292850 | 22999 | 55976196 |
Unresponsive to stimuli | 60.31 | 10.37 | 46 | 292826 | 31679 | 55967516 |
Osteonecrosis of jaw | 60.12 | 10.37 | 51 | 292821 | 33307 | 55965888 |
Ascites | 59.95 | 10.37 | 64 | 292808 | 37480 | 55961715 |
Pulmonary embolism | 58.78 | 10.37 | 322 | 292550 | 106802 | 55892393 |
Somnolence | 58.64 | 10.37 | 555 | 292317 | 162858 | 55836337 |
Rheumatoid nodule | 58.62 | 10.37 | 5 | 292867 | 14852 | 55984343 |
Urticaria chronic | 58.47 | 10.37 | 37 | 292835 | 548 | 55998647 |
Neoplasm progression | 57.64 | 10.37 | 49 | 292823 | 31967 | 55967228 |
Breast cancer | 57.21 | 10.37 | 104 | 292768 | 48729 | 55950466 |
Hepatic failure | 56.99 | 10.37 | 54 | 292818 | 33432 | 55965763 |
Urinary sediment present | 56.95 | 10.37 | 62 | 292810 | 2022 | 55997173 |
Respiratory disorder | 56.70 | 10.37 | 336 | 292536 | 33621 | 55965574 |
Live birth | 55.82 | 10.37 | 226 | 292646 | 19379 | 55979816 |
Body temperature increased | 54.11 | 10.37 | 334 | 292538 | 33908 | 55965287 |
Foetal exposure during pregnancy | 53.62 | 10.37 | 58 | 292814 | 33765 | 55965430 |
Pericardial effusion | 53.47 | 10.37 | 38 | 292834 | 27137 | 55972058 |
Encephalopathy | 53.36 | 10.37 | 63 | 292809 | 35262 | 55963933 |
Aspartate aminotransferase increased | 52.97 | 10.37 | 235 | 292637 | 82367 | 55916828 |
Blood creatine phosphokinase increased | 52.54 | 10.37 | 41 | 292831 | 27911 | 55971284 |
Pneumonitis | 52.44 | 10.37 | 52 | 292820 | 31512 | 55967683 |
Tremor | 52.11 | 10.37 | 392 | 292480 | 120697 | 55878498 |
Hypomagnesaemia | 51.88 | 10.37 | 33 | 292839 | 24982 | 55974213 |
Hypocalcaemia | 51.79 | 10.37 | 44 | 292828 | 28716 | 55970479 |
Acute myocardial infarction | 51.74 | 10.37 | 49 | 292823 | 30344 | 55968851 |
Sleep disorder | 51.60 | 10.37 | 559 | 292313 | 67104 | 55932091 |
Thrombosis | 51.46 | 10.37 | 149 | 292723 | 59278 | 55939917 |
Haematochezia | 51.31 | 10.37 | 93 | 292779 | 43625 | 55955570 |
Disseminated intravascular coagulation | 50.69 | 10.37 | 15 | 292857 | 17870 | 55981325 |
Rectal haemorrhage | 50.67 | 10.37 | 86 | 292786 | 41381 | 55957814 |
Osteomyelitis | 50.66 | 10.37 | 32 | 292840 | 24314 | 55974881 |
Therapeutic product effect incomplete | 50.64 | 10.37 | 333 | 292539 | 105698 | 55893497 |
Hypoxia | 50.52 | 10.37 | 130 | 292742 | 53767 | 55945428 |
Orthostatic hypotension | 50.37 | 10.37 | 59 | 292813 | 33140 | 55966055 |
Mental status changes | 50.37 | 10.37 | 73 | 292799 | 37428 | 55961767 |
Hepatotoxicity | 49.86 | 10.37 | 53 | 292819 | 31100 | 55968095 |
Serotonin syndrome | 49.60 | 10.37 | 39 | 292833 | 26451 | 55972744 |
Anticipatory anxiety | 49.41 | 10.37 | 42 | 292830 | 1000 | 55998195 |
Neuropathy peripheral | 49.22 | 10.37 | 323 | 292549 | 102570 | 55896625 |
Neutrophil count decreased | 49.18 | 10.37 | 117 | 292755 | 49705 | 55949490 |
Neurotoxicity | 49.07 | 10.37 | 11 | 292861 | 15784 | 55983411 |
Blood pressure fluctuation | 49.05 | 10.37 | 84 | 292788 | 40276 | 55958919 |
Hyperglycaemia | 49.02 | 10.37 | 77 | 292795 | 38204 | 55960991 |
Product prescribing error | 48.90 | 10.37 | 30 | 292842 | 23156 | 55976039 |
Cerebral haemorrhage | 48.84 | 10.37 | 46 | 292826 | 28560 | 55970635 |
Electrocardiogram QT prolonged | 48.64 | 10.37 | 135 | 292737 | 54453 | 55944742 |
Transaminases increased | 48.26 | 10.37 | 47 | 292825 | 28723 | 55970472 |
Colitis | 48.13 | 10.37 | 90 | 292782 | 41721 | 55957474 |
Premature baby | 47.76 | 10.37 | 20 | 292852 | 19185 | 55980010 |
Fracture | 47.73 | 10.37 | 17 | 292855 | 18001 | 55981194 |
Palmar-plantar erythrodysaesthesia syndrome | 47.66 | 10.37 | 25 | 292847 | 21040 | 55978155 |
Haemoglobin urine present | 47.56 | 10.37 | 37 | 292835 | 774 | 55998421 |
Proteinuria | 47.54 | 10.37 | 16 | 292856 | 17554 | 55981641 |
Blood immunoglobulin E increased | 47.53 | 10.37 | 68 | 292804 | 2941 | 55996254 |
Lung neoplasm malignant | 46.79 | 10.37 | 16 | 292856 | 17380 | 55981815 |
Immunodeficiency | 46.60 | 10.37 | 187 | 292685 | 15970 | 55983225 |
Abdominal pain | 46.55 | 10.37 | 1009 | 291863 | 257796 | 55741399 |
Haematuria | 46.54 | 10.37 | 43 | 292829 | 26944 | 55972251 |
Product dose omission issue | 46.47 | 10.37 | 767 | 292105 | 203986 | 55795209 |
Tachycardia | 45.91 | 10.37 | 342 | 292530 | 105534 | 55893661 |
Lymphocyte percentage decreased | 45.82 | 10.37 | 65 | 292807 | 2789 | 55996406 |
Blood bilirubin increased | 45.71 | 10.37 | 64 | 292808 | 33290 | 55965905 |
Blood glucose increased | 45.69 | 10.37 | 218 | 292654 | 74933 | 55924262 |
Arthralgia | 45.34 | 10.37 | 3109 | 289763 | 498560 | 55500635 |
Hip fracture | 45.32 | 10.37 | 44 | 292828 | 26929 | 55972266 |
Adverse event | 45.28 | 10.37 | 464 | 292408 | 54912 | 55944283 |
Bursitis | 44.82 | 10.37 | 271 | 292601 | 27311 | 55971884 |
Anaphylactic reaction | 44.80 | 10.37 | 487 | 292385 | 58508 | 55940687 |
Localised infection | 44.58 | 10.37 | 46 | 292826 | 27366 | 55971829 |
Accidental exposure to product | 44.03 | 10.37 | 38 | 292834 | 24609 | 55974586 |
Creatinine renal clearance decreased | 43.53 | 10.37 | 11 | 292861 | 14548 | 55984647 |
C-reactive protein increased | 43.44 | 10.37 | 236 | 292636 | 78448 | 55920747 |
Peritonitis | 43.41 | 10.37 | 15 | 292857 | 16187 | 55983008 |
Blood lactate dehydrogenase increased | 43.26 | 10.37 | 27 | 292845 | 20648 | 55978547 |
Retinitis | 42.79 | 10.37 | 78 | 292794 | 4146 | 55995049 |
Bacteraemia | 42.70 | 10.37 | 14 | 292858 | 15617 | 55983578 |
Acute respiratory distress syndrome | 42.70 | 10.37 | 31 | 292841 | 21895 | 55977300 |
Pulmonary hypertension | 42.60 | 10.37 | 76 | 292796 | 35868 | 55963327 |
Musculoskeletal stiffness | 42.59 | 10.37 | 1088 | 291784 | 154919 | 55844276 |
Osteonecrosis | 42.44 | 10.37 | 35 | 292837 | 23180 | 55976015 |
Myelosuppression | 42.10 | 10.37 | 19 | 292853 | 17436 | 55981759 |
Gait disturbance | 42.09 | 10.37 | 597 | 292275 | 162724 | 55836471 |
Wrong technique in product usage process | 41.98 | 10.37 | 158 | 292714 | 58010 | 55941185 |
Inappropriate antidiuretic hormone secretion | 41.89 | 10.37 | 10 | 292862 | 13746 | 55985449 |
Skin necrosis | 41.79 | 10.37 | 7 | 292865 | 12354 | 55986841 |
Renal tubular necrosis | 41.76 | 10.37 | 4 | 292868 | 10824 | 55988371 |
White blood cells urine positive | 41.64 | 10.37 | 83 | 292789 | 4719 | 55994476 |
Adjustment disorder with depressed mood | 41.63 | 10.37 | 86 | 292786 | 5017 | 55994178 |
Dizziness | 41.54 | 10.37 | 1569 | 291303 | 374571 | 55624624 |
Drug hypersensitivity | 41.48 | 10.37 | 1102 | 291770 | 274103 | 55725092 |
Myalgia | 41.35 | 10.37 | 463 | 292409 | 131562 | 55867633 |
Urine abnormality | 41.32 | 10.37 | 101 | 292771 | 6598 | 55992597 |
Blood pressure increased | 41.29 | 10.37 | 520 | 292352 | 144656 | 55854539 |
Pain in jaw | 41.14 | 10.37 | 92 | 292780 | 39944 | 55959251 |
Neoplasm malignant | 41.13 | 10.37 | 48 | 292824 | 27007 | 55972188 |
Metastases to central nervous system | 40.75 | 10.37 | 7 | 292865 | 12129 | 55987066 |
Syncope | 40.73 | 10.37 | 363 | 292509 | 107836 | 55891359 |
Posterior reversible encephalopathy syndrome | 40.70 | 10.37 | 16 | 292856 | 15944 | 55983251 |
Bradycardia | 40.35 | 10.37 | 197 | 292675 | 67307 | 55931888 |
Acute hepatic failure | 40.06 | 10.37 | 18 | 292854 | 16560 | 55982635 |
Gamma-glutamyltransferase increased | 40.04 | 10.37 | 62 | 292810 | 30943 | 55968252 |
Muscular weakness | 39.07 | 10.37 | 351 | 292521 | 104101 | 55895094 |
Psychotic disorder | 38.92 | 10.37 | 39 | 292833 | 23519 | 55975676 |
Chest pain | 38.89 | 10.37 | 724 | 292148 | 189073 | 55810122 |
Cardiomyopathy | 38.74 | 10.37 | 18 | 292854 | 16240 | 55982955 |
Cerebral infarction | 38.64 | 10.37 | 36 | 292836 | 22469 | 55976726 |
Haematoma | 38.58 | 10.37 | 67 | 292805 | 31952 | 55967243 |
Victim of chemical submission | 38.56 | 10.37 | 25 | 292847 | 387 | 55998808 |
Blood calcium decreased | 38.53 | 10.37 | 40 | 292832 | 23729 | 55975466 |
Infective pulmonary exacerbation of cystic fibrosis | 38.17 | 10.37 | 111 | 292761 | 8046 | 55991149 |
Agranulocytosis | 38.02 | 10.37 | 37 | 292835 | 22622 | 55976573 |
Agitation | 38.02 | 10.37 | 156 | 292716 | 55880 | 55943315 |
Respiratory depression | 37.95 | 10.37 | 9 | 292863 | 12426 | 55986769 |
Musculoskeletal pain | 37.68 | 10.37 | 257 | 292615 | 80895 | 55918300 |
Generalised tonic-clonic seizure | 37.67 | 10.37 | 53 | 292819 | 27513 | 55971682 |
Extrapyramidal disorder | 37.60 | 10.37 | 9 | 292863 | 12347 | 55986848 |
Drug use disorder | 37.29 | 10.37 | 78 | 292794 | 4591 | 55994604 |
Electrolyte imbalance | 37.11 | 10.37 | 24 | 292848 | 18009 | 55981186 |
Red blood cells urine positive | 37.06 | 10.37 | 60 | 292812 | 2896 | 55996299 |
Breast cancer metastatic | 37.06 | 10.37 | 17 | 292855 | 15452 | 55983743 |
General physical health deterioration | 37.01 | 10.37 | 1152 | 291720 | 168858 | 55830337 |
Epistaxis | 37.01 | 10.37 | 201 | 292671 | 66822 | 55932373 |
Maternal exposure timing unspecified | 36.96 | 10.37 | 85 | 292787 | 5338 | 55993857 |
Rash erythematous | 36.96 | 10.37 | 325 | 292547 | 36896 | 55962299 |
Haematemesis | 36.67 | 10.37 | 58 | 292814 | 28700 | 55970495 |
Metastases to liver | 36.51 | 10.37 | 35 | 292837 | 21551 | 55977644 |
Cataract | 36.46 | 10.37 | 140 | 292732 | 51107 | 55948088 |
Neutrophil percentage increased | 36.46 | 10.37 | 58 | 292814 | 2758 | 55996437 |
Leukocytosis | 36.40 | 10.37 | 42 | 292830 | 23749 | 55975446 |
Cardiogenic shock | 36.02 | 10.37 | 20 | 292852 | 16305 | 55982890 |
Basal cell carcinoma | 35.98 | 10.37 | 47 | 292825 | 25174 | 55974021 |
Dislocation of vertebra | 35.95 | 10.37 | 84 | 292788 | 5331 | 55993864 |
Lip dry | 35.87 | 10.37 | 122 | 292750 | 9618 | 55989577 |
Cardiac disorder | 35.53 | 10.37 | 121 | 292751 | 45766 | 55953429 |
Acute respiratory failure | 35.42 | 10.37 | 67 | 292805 | 30927 | 55968268 |
Exposure during pregnancy | 35.22 | 10.37 | 944 | 291928 | 135398 | 55863797 |
Diabetes mellitus | 35.04 | 10.37 | 148 | 292724 | 52587 | 55946608 |
Auditory neuropathy spectrum disorder | 34.93 | 10.37 | 11 | 292861 | 22 | 55999173 |
Upper gastrointestinal haemorrhage | 34.68 | 10.37 | 23 | 292849 | 17031 | 55982164 |
Drug tolerance decreased | 34.59 | 10.37 | 150 | 292722 | 13261 | 55985934 |
Adverse drug reaction | 34.59 | 10.37 | 503 | 292369 | 64629 | 55934566 |
Influenza | 34.38 | 10.37 | 323 | 292549 | 94938 | 55904257 |
Gastric ulcer | 34.34 | 10.37 | 40 | 292832 | 22523 | 55976672 |
Hypophagia | 34.27 | 10.37 | 61 | 292811 | 28815 | 55970380 |
Cystitis | 34.23 | 10.37 | 135 | 292737 | 48903 | 55950292 |
Mechanical urticaria | 34.15 | 10.37 | 24 | 292848 | 427 | 55998768 |
Hereditary angioedema | 33.92 | 10.37 | 95 | 292777 | 6740 | 55992455 |
Tuberculosis | 33.62 | 10.37 | 8 | 292864 | 11021 | 55988174 |
Sedation | 33.49 | 10.37 | 83 | 292789 | 34771 | 55964424 |
Shock haemorrhagic | 33.14 | 10.37 | 4 | 292868 | 9029 | 55990166 |
Anuria | 33.08 | 10.37 | 10 | 292862 | 11750 | 55987445 |
Anti-cyclic citrullinated peptide antibody | 33.07 | 10.37 | 65 | 292807 | 3658 | 55995537 |
Therapy cessation | 32.89 | 10.37 | 57 | 292815 | 27207 | 55971988 |
Oliguria | 32.86 | 10.37 | 3 | 292869 | 8437 | 55990758 |
Blood potassium increased | 32.84 | 10.37 | 25 | 292847 | 17236 | 55981959 |
Transplant rejection | 32.77 | 10.37 | 6 | 292866 | 9928 | 55989267 |
Status epilepticus | 32.76 | 10.37 | 19 | 292853 | 15122 | 55984073 |
Haematotoxicity | 32.59 | 10.37 | 3 | 292869 | 8380 | 55990815 |
Metastases to bone | 32.57 | 10.37 | 32 | 292840 | 19476 | 55979719 |
Thrombotic microangiopathy | 32.56 | 10.37 | 5 | 292867 | 9406 | 55989789 |
Perfume sensitivity | 32.51 | 10.37 | 28 | 292844 | 679 | 55998516 |
Panniculitis | 32.34 | 10.37 | 6 | 292866 | 9836 | 55989359 |
Hospitalisation | 32.15 | 10.37 | 243 | 292629 | 74757 | 55924438 |
Renal disorder | 32.11 | 10.37 | 66 | 292806 | 29539 | 55969656 |
Subdural haematoma | 32.08 | 10.37 | 15 | 292857 | 13484 | 55985711 |
Neonatal hypoacusis | 31.76 | 10.37 | 10 | 292862 | 20 | 55999175 |
Temperature intolerance | 31.65 | 10.37 | 103 | 292769 | 7937 | 55991258 |
Bone disorder | 31.55 | 10.37 | 33 | 292839 | 19510 | 55979685 |
Enthesopathy | 31.04 | 10.37 | 3 | 292869 | 8060 | 55991135 |
Eye pruritus | 30.80 | 10.37 | 151 | 292721 | 14055 | 55985140 |
Post-traumatic stress disorder | 30.79 | 10.37 | 71 | 292801 | 4467 | 55994728 |
Urine leukocyte esterase positive | 30.73 | 10.37 | 57 | 292815 | 3071 | 55996124 |
Transient ischaemic attack | 30.69 | 10.37 | 82 | 292790 | 33495 | 55965700 |
Blood pressure diastolic abnormal | 30.62 | 10.37 | 11 | 292861 | 11587 | 55987608 |
Labelled drug-drug interaction medication error | 30.57 | 10.37 | 11 | 292861 | 11575 | 55987620 |
Injection site pain | 30.56 | 10.37 | 427 | 292445 | 116691 | 55882504 |
Left ventricular dysfunction | 30.32 | 10.37 | 10 | 292862 | 11113 | 55988082 |
Eczema | 30.05 | 10.37 | 236 | 292636 | 25917 | 55973278 |
Cholestasis | 30.04 | 10.37 | 59 | 292813 | 26854 | 55972341 |
Clostridium difficile colitis | 29.85 | 10.37 | 32 | 292840 | 18706 | 55980489 |
Stress cardiomyopathy | 29.84 | 10.37 | 4 | 292868 | 8332 | 55990863 |
Myelodysplastic syndrome | 29.66 | 10.37 | 25 | 292847 | 16381 | 55982814 |
Red blood cell sedimentation rate abnormal | 29.62 | 10.37 | 32 | 292840 | 18641 | 55980554 |
Accidental overdose | 29.32 | 10.37 | 38 | 292834 | 20423 | 55978772 |
Blood alkaline phosphatase increased | 29.28 | 10.37 | 104 | 292768 | 38841 | 55960354 |
Facet joint syndrome | 29.15 | 10.37 | 89 | 292783 | 6628 | 55992567 |
Hepatitis | 29.14 | 10.37 | 91 | 292781 | 35350 | 55963845 |
Deep vein thrombosis | 29.08 | 10.37 | 258 | 292614 | 76719 | 55922476 |
Ventricular tachycardia | 29.06 | 10.37 | 27 | 292845 | 16874 | 55982321 |
Cardiotoxicity | 29.05 | 10.37 | 3 | 292869 | 7647 | 55991548 |
Pancreatitis | 29.04 | 10.37 | 128 | 292744 | 44952 | 55954243 |
Oxygen saturation decreased | 28.99 | 10.37 | 267 | 292605 | 78800 | 55920395 |
Pancreatitis acute | 28.99 | 10.37 | 54 | 292818 | 25070 | 55974125 |
Intervertebral discitis | 28.64 | 10.37 | 52 | 292820 | 2755 | 55996440 |
Hypertensive crisis | 28.45 | 10.37 | 19 | 292853 | 14017 | 55985178 |
Inappropriate schedule of product administration | 28.29 | 10.37 | 287 | 292585 | 83100 | 55916095 |
Angina pectoris | 28.16 | 10.37 | 65 | 292807 | 27911 | 55971284 |
Intentional product misuse | 28.13 | 10.37 | 155 | 292717 | 51349 | 55947846 |
Blood pressure systolic increased | 28.13 | 10.37 | 113 | 292759 | 40723 | 55958472 |
Hypothyroidism | 28.05 | 10.37 | 103 | 292769 | 38093 | 55961102 |
Aphasia | 28.01 | 10.37 | 74 | 292798 | 30341 | 55968854 |
Suicide attempt | 27.93 | 10.37 | 181 | 292691 | 57655 | 55941540 |
Urine analysis abnormal | 27.92 | 10.37 | 70 | 292802 | 4647 | 55994548 |
Escherichia infection | 27.80 | 10.37 | 13 | 292859 | 11686 | 55987509 |
Myoclonus | 27.69 | 10.37 | 23 | 292849 | 15180 | 55984015 |
Spinal compression fracture | 27.69 | 10.37 | 17 | 292855 | 13117 | 55986078 |
Influenza like illness | 27.39 | 10.37 | 195 | 292677 | 60793 | 55938402 |
Vocal cord dysfunction | 27.34 | 10.37 | 20 | 292852 | 380 | 55998815 |
Ejection fraction decreased | 27.26 | 10.37 | 38 | 292834 | 19803 | 55979392 |
Pneumocystis jirovecii pneumonia | 27.09 | 10.37 | 25 | 292847 | 15676 | 55983519 |
Therapy interrupted | 27.06 | 10.37 | 58 | 292814 | 25567 | 55973628 |
Mast cell activation syndrome | 27.05 | 10.37 | 25 | 292847 | 667 | 55998528 |
Akathisia | 26.93 | 10.37 | 6 | 292866 | 8646 | 55990549 |
Blood pressure decreased | 26.91 | 10.37 | 188 | 292684 | 58862 | 55940333 |
Rib fracture | 26.82 | 10.37 | 40 | 292832 | 20269 | 55978926 |
Diverticulitis | 26.78 | 10.37 | 96 | 292776 | 35756 | 55963439 |
Nervous system disorder | 26.73 | 10.37 | 29 | 292843 | 16860 | 55982335 |
Muscle rigidity | 26.72 | 10.37 | 11 | 292861 | 10660 | 55988535 |
Ileus | 26.55 | 10.37 | 20 | 292852 | 13862 | 55985333 |
Respiratory distress | 26.26 | 10.37 | 81 | 292791 | 31586 | 55967609 |
Spinal fracture | 26.22 | 10.37 | 28 | 292844 | 16396 | 55982799 |
Haemorrhage intracranial | 26.21 | 10.37 | 17 | 292855 | 12738 | 55986457 |
Hypervolaemia | 26.21 | 10.37 | 62 | 292810 | 26396 | 55972799 |
Eosinophilic colitis | 26.18 | 10.37 | 14 | 292858 | 148 | 55999047 |
Arrhythmia | 26.16 | 10.37 | 94 | 292778 | 34989 | 55964206 |
Tachypnoea | 26.12 | 10.37 | 25 | 292847 | 15405 | 55983790 |
Urinary retention | 26.08 | 10.37 | 68 | 292804 | 28006 | 55971189 |
Tooth disorder | 26.02 | 10.37 | 59 | 292813 | 25494 | 55973701 |
Diffuse large B-cell lymphoma | 26.01 | 10.37 | 3 | 292869 | 7013 | 55992182 |
Polyneuropathy | 26.00 | 10.37 | 18 | 292854 | 13032 | 55986163 |
Schizophrenia | 26.00 | 10.37 | 11 | 292861 | 10488 | 55988707 |
Iron deficiency anaemia | 25.96 | 10.37 | 33 | 292839 | 17886 | 55981309 |
Treatment noncompliance | 25.96 | 10.37 | 85 | 292787 | 32538 | 55966657 |
Lethargy | 25.86 | 10.37 | 159 | 292713 | 51282 | 55947913 |
Intestinal obstruction | 25.80 | 10.37 | 68 | 292804 | 27903 | 55971292 |
Toxic epidermal necrolysis | 25.76 | 10.37 | 47 | 292825 | 21995 | 55977200 |
Surgery | 25.60 | 10.37 | 85 | 292787 | 32401 | 55966794 |
Chronic obstructive pulmonary disease | 25.58 | 10.37 | 184 | 292688 | 57231 | 55941964 |
Pulmonary arterial hypertension | 25.55 | 10.37 | 63 | 292809 | 26440 | 55972755 |
Pulmonary toxicity | 25.49 | 10.37 | 5 | 292867 | 7878 | 55991317 |
Skin laceration | 25.37 | 10.37 | 41 | 292831 | 20115 | 55979080 |
Blood urea increased | 25.34 | 10.37 | 56 | 292816 | 24417 | 55974778 |
Clostridium difficile infection | 25.18 | 10.37 | 66 | 292806 | 27132 | 55972063 |
Chills | 25.05 | 10.37 | 379 | 292493 | 102225 | 55896970 |
Deep vein thrombosis postoperative | 25.00 | 10.37 | 61 | 292811 | 3980 | 55995215 |
Musculoskeletal disorder | 25.00 | 10.37 | 38 | 292834 | 19109 | 55980086 |
Chronic sinusitis | 24.99 | 10.37 | 98 | 292774 | 8280 | 55990915 |
Hemiparesis | 24.96 | 10.37 | 46 | 292826 | 21444 | 55977751 |
Klebsiella infection | 24.91 | 10.37 | 5 | 292867 | 7751 | 55991444 |
Throat irritation | 24.90 | 10.37 | 270 | 292602 | 32413 | 55966782 |
Restrictive pulmonary disease | 24.86 | 10.37 | 35 | 292837 | 1491 | 55997704 |
Blood potassium decreased | 24.79 | 10.37 | 110 | 292762 | 38562 | 55960633 |
Head deformity | 24.78 | 10.37 | 12 | 292860 | 101 | 55999094 |
Seasonal allergy | 24.64 | 10.37 | 163 | 292709 | 16945 | 55982250 |
Blood pressure systolic abnormal | 24.60 | 10.37 | 10 | 292862 | 9767 | 55989428 |
Oral pruritus | 24.37 | 10.37 | 38 | 292834 | 1776 | 55997419 |
Vision blurred | 24.36 | 10.37 | 295 | 292577 | 82648 | 55916547 |
Drug eruption | 24.25 | 10.37 | 62 | 292810 | 25701 | 55973494 |
Premature labour | 24.20 | 10.37 | 16 | 292856 | 11866 | 55987329 |
Red blood cell count decreased | 24.18 | 10.37 | 103 | 292769 | 36514 | 55962681 |
Hallucination, auditory | 24.18 | 10.37 | 15 | 292857 | 11509 | 55987686 |
Mastocytosis | 24.15 | 10.37 | 21 | 292851 | 516 | 55998679 |
Diabetic ketoacidosis | 24.12 | 10.37 | 38 | 292834 | 18833 | 55980362 |
Urticaria thermal | 24.11 | 10.37 | 16 | 292856 | 258 | 55998937 |
Colitis ischaemic | 24.02 | 10.37 | 11 | 292861 | 10009 | 55989186 |
Neuroleptic malignant syndrome | 24.00 | 10.37 | 15 | 292857 | 11463 | 55987732 |
Febrile bone marrow aplasia | 23.89 | 10.37 | 3 | 292869 | 6569 | 55992626 |
Tubulointerstitial nephritis | 23.83 | 10.37 | 31 | 292841 | 16634 | 55982561 |
Balance disorder | 23.69 | 10.37 | 269 | 292603 | 76251 | 55922944 |
Loss of personal independence in daily activities | 23.67 | 10.37 | 290 | 292582 | 81079 | 55918116 |
Hyper IgE syndrome | 23.65 | 10.37 | 19 | 292853 | 417 | 55998778 |
Intestinal perforation | 23.36 | 10.37 | 14 | 292858 | 10945 | 55988250 |
Allergic reaction to excipient | 23.28 | 10.37 | 17 | 292855 | 322 | 55998873 |
Hepatic steatosis | 23.22 | 10.37 | 65 | 292807 | 26149 | 55973046 |
Dyskinesia | 23.05 | 10.37 | 76 | 292796 | 29032 | 55970163 |
No adverse event | 23.00 | 10.37 | 104 | 292768 | 36270 | 55962925 |
Drug withdrawal syndrome | 22.99 | 10.37 | 64 | 292808 | 25793 | 55973402 |
Headache | 22.89 | 10.37 | 3279 | 289593 | 555765 | 55443430 |
Pregnancy on contraceptive | 22.86 | 10.37 | 29 | 292843 | 1116 | 55998079 |
Haemorrhoids | 22.81 | 10.37 | 44 | 292828 | 20162 | 55979033 |
Dialysis | 22.72 | 10.37 | 11 | 292861 | 9691 | 55989504 |
Oral pain | 22.70 | 10.37 | 66 | 292806 | 26227 | 55972968 |
Autoimmune disorder | 22.65 | 10.37 | 100 | 292772 | 8909 | 55990286 |
Coronary artery disease | 22.64 | 10.37 | 83 | 292789 | 30713 | 55968482 |
Allergy test positive | 22.52 | 10.37 | 18 | 292854 | 392 | 55998803 |
Tenosynovitis | 22.52 | 10.37 | 19 | 292853 | 12442 | 55986753 |
Renal injury | 22.51 | 10.37 | 9 | 292863 | 8878 | 55990317 |
Device expulsion | 22.43 | 10.37 | 82 | 292790 | 30367 | 55968828 |
Low birth weight baby | 22.41 | 10.37 | 3 | 292869 | 6255 | 55992940 |
Ischaemic stroke | 22.40 | 10.37 | 33 | 292839 | 16809 | 55982386 |
Bone density decreased | 22.40 | 10.37 | 20 | 292852 | 12740 | 55986455 |
Forced expiratory volume decreased | 22.37 | 10.37 | 64 | 292808 | 4596 | 55994599 |
Deafness | 22.25 | 10.37 | 32 | 292840 | 16462 | 55982733 |
Malnutrition | 22.23 | 10.37 | 24 | 292848 | 13984 | 55985211 |
Ankylosing spondylitis | 22.15 | 10.37 | 12 | 292860 | 9918 | 55989277 |
Full blood count decreased | 22.12 | 10.37 | 56 | 292816 | 23293 | 55975902 |
Therapeutic response decreased | 22.11 | 10.37 | 172 | 292700 | 52586 | 55946609 |
Lymphadenopathy | 22.06 | 10.37 | 101 | 292771 | 35107 | 55964088 |
Off label use | 21.85 | 10.37 | 2547 | 290325 | 553633 | 55445562 |
Drug level decreased | 21.78 | 10.37 | 5 | 292867 | 7059 | 55992136 |
Mouth ulceration | 21.72 | 10.37 | 80 | 292792 | 29560 | 55969635 |
Dyspnoea exertional | 21.68 | 10.37 | 181 | 292691 | 54508 | 55944687 |
Hypotonia | 21.63 | 10.37 | 9 | 292863 | 8668 | 55990527 |
Acidosis | 21.57 | 10.37 | 14 | 292858 | 10487 | 55988708 |
Skin plaque | 21.54 | 10.37 | 83 | 292789 | 6955 | 55992240 |
Nocturnal fear | 21.46 | 10.37 | 6 | 292866 | 6 | 55999189 |
Lupus vulgaris | 21.31 | 10.37 | 37 | 292835 | 1892 | 55997303 |
Gastroenteritis | 21.28 | 10.37 | 61 | 292811 | 24351 | 55974844 |
X-ray abnormal | 21.21 | 10.37 | 60 | 292812 | 4281 | 55994914 |
Hepatocellular injury | 21.15 | 10.37 | 69 | 292803 | 26445 | 55972750 |
Haematocrit decreased | 21.13 | 10.37 | 109 | 292763 | 36720 | 55962475 |
Cestode infection | 21.10 | 10.37 | 15 | 292857 | 272 | 55998923 |
Metastases to lung | 21.01 | 10.37 | 18 | 292854 | 11700 | 55987495 |
Mitral valve incompetence | 20.96 | 10.37 | 39 | 292833 | 18114 | 55981081 |
Caesarean section | 20.95 | 10.37 | 32 | 292840 | 16059 | 55983136 |
Breast cancer female | 20.87 | 10.37 | 20 | 292852 | 12318 | 55986877 |
Cardiac failure acute | 20.87 | 10.37 | 10 | 292862 | 8863 | 55990332 |
Bone pain | 20.85 | 10.37 | 164 | 292708 | 50021 | 55949174 |
Humerus fracture | 20.84 | 10.37 | 8 | 292864 | 8089 | 55991106 |
Encephalitis | 20.81 | 10.37 | 8 | 292864 | 8082 | 55991113 |
Arthritis | 20.71 | 10.37 | 380 | 292492 | 99472 | 55899723 |
Tricuspid valve incompetence | 20.70 | 10.37 | 23 | 292849 | 13230 | 55985965 |
Unevaluable event | 20.68 | 10.37 | 154 | 292718 | 47533 | 55951662 |
Cognitive disorder | 20.68 | 10.37 | 160 | 292712 | 48973 | 55950222 |
Cystic fibrosis pancreatic | 20.48 | 10.37 | 9 | 292863 | 59 | 55999136 |
Scratch | 20.47 | 10.37 | 70 | 292802 | 5533 | 55993662 |
Bronchial neoplasm | 20.44 | 10.37 | 18 | 292854 | 450 | 55998745 |
Incorrect dose administered | 20.34 | 10.37 | 175 | 292697 | 52372 | 55946823 |
Lichen sclerosus | 20.30 | 10.37 | 26 | 292846 | 1010 | 55998185 |
Heart rate decreased | 20.30 | 10.37 | 125 | 292747 | 40302 | 55958893 |
Malaise | 20.12 | 10.37 | 1644 | 291228 | 366216 | 55632979 |
Psoriasis | 20.10 | 10.37 | 350 | 292522 | 92342 | 55906853 |
Ovarian cancer | 20.08 | 10.37 | 4 | 292868 | 6234 | 55992961 |
Ear infection | 20.04 | 10.37 | 250 | 292622 | 31045 | 55968150 |
Diabetes mellitus inadequate control | 19.99 | 10.37 | 26 | 292846 | 13954 | 55985241 |
Victim of sexual abuse | 19.96 | 10.37 | 20 | 292852 | 591 | 55998604 |
Device difficult to use | 19.95 | 10.37 | 16 | 292856 | 10745 | 55988450 |
Pallor | 19.86 | 10.37 | 62 | 292810 | 24087 | 55975108 |
Burning sensation | 19.83 | 10.37 | 160 | 292712 | 48536 | 55950659 |
Unintentional medical device removal | 19.76 | 10.37 | 3 | 292869 | 5691 | 55993504 |
Enteritis | 19.75 | 10.37 | 7 | 292865 | 7436 | 55991759 |
Hallucination, visual | 19.75 | 10.37 | 38 | 292834 | 17430 | 55981765 |
Haemodialysis | 19.73 | 10.37 | 10 | 292862 | 8581 | 55990614 |
Fibromyalgia | 19.72 | 10.37 | 427 | 292445 | 59176 | 55940019 |
Failure to thrive | 19.57 | 10.37 | 5 | 292867 | 6565 | 55992630 |
Crepitations | 19.53 | 10.37 | 6 | 292866 | 6978 | 55992217 |
Femoral neck fracture | 19.47 | 10.37 | 8 | 292864 | 7763 | 55991432 |
Heart rate irregular | 19.28 | 10.37 | 50 | 292822 | 20629 | 55978566 |
Faeces discoloured | 19.19 | 10.37 | 37 | 292835 | 16959 | 55982236 |
Sopor | 19.19 | 10.37 | 51 | 292821 | 20871 | 55978324 |
Right ventricular failure | 19.08 | 10.37 | 35 | 292837 | 16344 | 55982851 |
Candida infection | 18.99 | 10.37 | 69 | 292803 | 25598 | 55973597 |
Schizophreniform disorder | 18.87 | 10.37 | 9 | 292863 | 73 | 55999122 |
Abdominal distension | 18.85 | 10.37 | 287 | 292585 | 77339 | 55921856 |
Seronegative arthritis | 18.77 | 10.37 | 43 | 292829 | 2693 | 55996502 |
Gastric haemorrhage | 18.77 | 10.37 | 4 | 292868 | 5946 | 55993249 |
Product use in unapproved indication | 18.47 | 10.37 | 903 | 291969 | 139919 | 55859276 |
Condition aggravated | 18.46 | 10.37 | 2057 | 290815 | 342841 | 55656354 |
Drug reaction with eosinophilia and systemic symptoms | 18.36 | 10.37 | 88 | 292784 | 30216 | 55968979 |
Lung infiltration | 18.19 | 10.37 | 27 | 292845 | 13711 | 55985484 |
Liver function test increased | 18.05 | 10.37 | 80 | 292792 | 28053 | 55971142 |
Dementia | 17.98 | 10.37 | 39 | 292833 | 17119 | 55982076 |
Therapy partial responder | 17.97 | 10.37 | 9 | 292863 | 7776 | 55991419 |
Torsade de pointes | 17.93 | 10.37 | 23 | 292849 | 12417 | 55986778 |
Visual acuity reduced | 17.91 | 10.37 | 52 | 292820 | 20674 | 55978521 |
Histamine level increased | 17.87 | 10.37 | 6 | 292866 | 16 | 55999179 |
Systemic inflammatory response syndrome | 17.82 | 10.37 | 3 | 292869 | 5275 | 55993920 |
Multiple fractures | 17.69 | 10.37 | 8 | 292864 | 7333 | 55991862 |
Coagulopathy | 17.64 | 10.37 | 45 | 292827 | 18671 | 55980524 |
Hyperpathia | 17.61 | 10.37 | 6 | 292866 | 17 | 55999178 |
Hallucination | 17.57 | 10.37 | 167 | 292705 | 48982 | 55950213 |
Immune reconstitution inflammatory syndrome | 17.53 | 10.37 | 4 | 292868 | 5670 | 55993525 |
Device malfunction | 17.47 | 10.37 | 36 | 292836 | 16100 | 55983095 |
Nasal turbinate hypertrophy | 17.41 | 10.37 | 20 | 292852 | 693 | 55998502 |
Haemodynamic instability | 17.25 | 10.37 | 11 | 292861 | 8318 | 55990877 |
Bacterial test positive | 17.23 | 10.37 | 61 | 292811 | 4907 | 55994288 |
Antinuclear antibody positive | 17.21 | 10.37 | 7 | 292865 | 6834 | 55992361 |
Mental disorder | 17.10 | 10.37 | 64 | 292808 | 23540 | 55975655 |
Spinal pain | 17.10 | 10.37 | 22 | 292850 | 11862 | 55987333 |
Troponin increased | 17.09 | 10.37 | 12 | 292860 | 8623 | 55990572 |
Vaginal haemorrhage | 17.08 | 10.37 | 72 | 292800 | 25601 | 55973594 |
Gastric disorder | 17.03 | 10.37 | 102 | 292770 | 33108 | 55966087 |
Atelectasis | 17.01 | 10.37 | 48 | 292824 | 19260 | 55979935 |
Sudden death | 17.00 | 10.37 | 15 | 292857 | 9610 | 55989585 |
Exposure via body fluid | 16.98 | 10.37 | 17 | 292855 | 502 | 55998693 |
Nephrolithiasis | 16.95 | 10.37 | 119 | 292753 | 37216 | 55961979 |
White blood cell count increased | 16.90 | 10.37 | 150 | 292722 | 44609 | 55954586 |
Head injury | 16.86 | 10.37 | 70 | 292802 | 24996 | 55974199 |
Device issue | 16.79 | 10.37 | 55 | 292817 | 21051 | 55978144 |
Brain oedema | 16.70 | 10.37 | 27 | 292845 | 13244 | 55985951 |
Circulatory collapse | 16.69 | 10.37 | 54 | 292818 | 20749 | 55978446 |
Grip strength decreased | 16.69 | 10.37 | 143 | 292729 | 16113 | 55983082 |
Anaphylactoid reaction | 16.68 | 10.37 | 48 | 292824 | 3458 | 55995737 |
Electrocardiogram QRS complex prolonged | 16.60 | 10.37 | 4 | 292868 | 5463 | 55993732 |
Rash pustular | 16.47 | 10.37 | 7 | 292865 | 6656 | 55992539 |
Second primary malignancy | 16.43 | 10.37 | 9 | 292863 | 7393 | 55991802 |
Hepatic encephalopathy | 16.40 | 10.37 | 17 | 292855 | 10093 | 55989102 |
Lymphoma | 16.40 | 10.37 | 18 | 292854 | 10410 | 55988785 |
Back pain | 16.34 | 10.37 | 1039 | 291833 | 236131 | 55763064 |
Blood pressure diastolic decreased | 16.32 | 10.37 | 49 | 292823 | 19274 | 55979921 |
Malignant melanoma | 16.31 | 10.37 | 19 | 292853 | 10700 | 55988495 |
Cytopenia | 16.29 | 10.37 | 16 | 292856 | 9739 | 55989456 |
Stillbirth | 16.23 | 10.37 | 6 | 292866 | 6208 | 55992987 |
Injection site haemorrhage | 16.21 | 10.37 | 60 | 292812 | 22141 | 55977054 |
Diarrhoea haemorrhagic | 16.15 | 10.37 | 11 | 292861 | 8032 | 55991163 |
Prothrombin time prolonged | 16.14 | 10.37 | 14 | 292858 | 9046 | 55990149 |
Peripheral sensory neuropathy | 16.12 | 10.37 | 8 | 292864 | 6948 | 55992247 |
Atopy | 16.09 | 10.37 | 12 | 292860 | 235 | 55998960 |
Lichen nitidus | 16.06 | 10.37 | 8 | 292864 | 72 | 55999123 |
Staphylococcal infection | 16.06 | 10.37 | 122 | 292750 | 37496 | 55961699 |
Granulocytopenia | 16.05 | 10.37 | 4 | 292868 | 5340 | 55993855 |
Ventricular fibrillation | 16.04 | 10.37 | 20 | 292852 | 10932 | 55988263 |
Hypothermia | 16.04 | 10.37 | 25 | 292847 | 12445 | 55986750 |
Bronchial haemorrhage | 15.98 | 10.37 | 17 | 292855 | 540 | 55998655 |
Monocyte count abnormal | 15.93 | 10.37 | 11 | 292861 | 190 | 55999005 |
Poisoning deliberate | 15.85 | 10.37 | 17 | 292855 | 9936 | 55989259 |
Peripheral venous disease | 15.72 | 10.37 | 98 | 292774 | 9981 | 55989214 |
Ataxia | 15.71 | 10.37 | 32 | 292840 | 14371 | 55984824 |
Tumour lysis syndrome | 15.69 | 10.37 | 11 | 292861 | 7912 | 55991283 |
Product administration error | 15.65 | 10.37 | 56 | 292816 | 20873 | 55978322 |
Hydronephrosis | 15.61 | 10.37 | 15 | 292857 | 9227 | 55989968 |
Metastasis | 15.54 | 10.37 | 3 | 292869 | 4781 | 55994414 |
Sinus tachycardia | 15.53 | 10.37 | 62 | 292810 | 22382 | 55976813 |
Splenomegaly | 15.50 | 10.37 | 18 | 292854 | 10150 | 55989045 |
Eating disorder | 15.46 | 10.37 | 42 | 292830 | 17063 | 55982132 |
Duodenal ulcer | 15.45 | 10.37 | 9 | 292863 | 7146 | 55992049 |
Menstruation delayed | 15.44 | 10.37 | 28 | 292844 | 1482 | 55997713 |
Dysphagia | 15.42 | 10.37 | 317 | 292555 | 81630 | 55917565 |
Urinary casts | 15.39 | 10.37 | 19 | 292853 | 711 | 55998484 |
Atrioventricular block first degree | 15.35 | 10.37 | 8 | 292864 | 6757 | 55992438 |
Oral allergy syndrome | 15.32 | 10.37 | 6 | 292866 | 28 | 55999167 |
Lip pruritus | 15.30 | 10.37 | 20 | 292852 | 793 | 55998402 |
Epstein-Barr virus infection | 15.26 | 10.37 | 10 | 292862 | 7453 | 55991742 |
Foot fracture | 15.24 | 10.37 | 60 | 292812 | 21749 | 55977446 |
Faecaloma | 15.18 | 10.37 | 10 | 292862 | 7431 | 55991764 |
Cyst | 15.15 | 10.37 | 27 | 292845 | 12751 | 55986444 |
Blood pressure systolic decreased | 15.15 | 10.37 | 7 | 292865 | 6336 | 55992859 |
Blood albumin decreased | 15.10 | 10.37 | 30 | 292842 | 13598 | 55985597 |
Urinary incontinence | 15.10 | 10.37 | 91 | 292781 | 29494 | 55969701 |
Laryngitis | 15.07 | 10.37 | 124 | 292748 | 13806 | 55985389 |
Gangrene | 15.07 | 10.37 | 5 | 292867 | 5535 | 55993660 |
Disorientation | 15.05 | 10.37 | 120 | 292752 | 36493 | 55962702 |
Walking aid user | 15.04 | 10.37 | 85 | 292787 | 8358 | 55990837 |
Hemiplegia | 14.96 | 10.37 | 13 | 292859 | 8391 | 55990804 |
Hepatic cytolysis | 14.87 | 10.37 | 21 | 292851 | 10885 | 55988310 |
Pregnancy | 14.82 | 10.37 | 248 | 292624 | 32785 | 55966410 |
Cardiovascular disorder | 14.81 | 10.37 | 21 | 292851 | 10868 | 55988327 |
Paraesthesia oral | 14.78 | 10.37 | 127 | 292745 | 14322 | 55984873 |
Device use error | 14.71 | 10.37 | 5 | 292867 | 5451 | 55993744 |
Oesophagitis | 14.69 | 10.37 | 32 | 292840 | 14025 | 55985170 |
Breast cancer stage I | 14.69 | 10.37 | 7 | 292865 | 6223 | 55992972 |
Hyperbilirubinaemia | 14.67 | 10.37 | 19 | 292853 | 10216 | 55988979 |
Intestinal ischaemia | 14.66 | 10.37 | 9 | 292863 | 6946 | 55992249 |
Magnesium deficiency | 14.62 | 10.37 | 16 | 292856 | 525 | 55998670 |
Osteopenia | 14.62 | 10.37 | 47 | 292825 | 18094 | 55981101 |
Venous thrombosis | 14.61 | 10.37 | 3 | 292869 | 4577 | 55994618 |
Gastritis | 14.60 | 10.37 | 113 | 292759 | 34589 | 55964606 |
Bacterial infection | 14.60 | 10.37 | 44 | 292828 | 17286 | 55981909 |
Pulmonary mass | 14.51 | 10.37 | 56 | 292816 | 20414 | 55978781 |
Colon cancer | 14.49 | 10.37 | 17 | 292855 | 9544 | 55989651 |
Urine output decreased | 14.45 | 10.37 | 21 | 292851 | 10756 | 55988439 |
Pancreatic carcinoma | 14.41 | 10.37 | 10 | 292862 | 7231 | 55991964 |
Muscle atrophy | 14.37 | 10.37 | 8 | 292864 | 6513 | 55992682 |
Cholangitis | 14.30 | 10.37 | 4 | 292868 | 4945 | 55994250 |
Tongue pruritus | 14.29 | 10.37 | 15 | 292857 | 469 | 55998726 |
Myocarditis | 14.25 | 10.37 | 15 | 292857 | 8843 | 55990352 |
Fistula | 14.24 | 10.37 | 15 | 292857 | 8840 | 55990355 |
Atrial flutter | 14.23 | 10.37 | 16 | 292856 | 9153 | 55990042 |
Female genital tract fistula | 14.21 | 10.37 | 3 | 292869 | 4489 | 55994706 |
Injection site erythema | 14.16 | 10.37 | 301 | 292571 | 77147 | 55922048 |
Large intestine perforation | 14.15 | 10.37 | 12 | 292860 | 7839 | 55991356 |
Prevertebral soft tissue swelling of cervical space | 14.10 | 10.37 | 6 | 292866 | 36 | 55999159 |
Eye infection bacterial | 14.07 | 10.37 | 9 | 292863 | 136 | 55999059 |
Flatulence | 14.07 | 10.37 | 100 | 292772 | 31188 | 55968007 |
Abdominal pain lower | 14.02 | 10.37 | 67 | 292805 | 23025 | 55976170 |
Food intolerance | 14 | 10.37 | 39 | 292833 | 2758 | 55996437 |
Aspergillus infection | 13.96 | 10.37 | 11 | 292861 | 7454 | 55991741 |
Sinus node dysfunction | 13.95 | 10.37 | 3 | 292869 | 4431 | 55994764 |
Dysarthria | 13.88 | 10.37 | 135 | 292737 | 39415 | 55959780 |
Hypoalbuminaemia | 13.87 | 10.37 | 21 | 292851 | 10578 | 55988617 |
Kidney infection | 13.87 | 10.37 | 58 | 292814 | 20667 | 55978528 |
Glomerular filtration rate decreased | 13.78 | 10.37 | 27 | 292845 | 12302 | 55986893 |
Glycosylated haemoglobin increased | 13.78 | 10.37 | 23 | 292849 | 11142 | 55988053 |
Respirovirus test positive | 13.78 | 10.37 | 5 | 292867 | 18 | 55999177 |
Renal cyst | 13.64 | 10.37 | 17 | 292855 | 9292 | 55989903 |
Speech disorder | 13.57 | 10.37 | 127 | 292745 | 37366 | 55961829 |
Colitis ulcerative | 13.54 | 10.37 | 73 | 292799 | 24318 | 55974877 |
Abdominal pain upper | 13.48 | 10.37 | 1090 | 291782 | 177223 | 55821972 |
Ehlers-Danlos syndrome | 13.47 | 10.37 | 9 | 292863 | 147 | 55999048 |
Muscle spasms | 13.40 | 10.37 | 581 | 292291 | 136790 | 55862405 |
Parkinsonism | 13.40 | 10.37 | 18 | 292854 | 9528 | 55989667 |
Abnormal behaviour | 13.40 | 10.37 | 57 | 292815 | 20215 | 55978980 |
Hypernatraemia | 13.37 | 10.37 | 9 | 292863 | 6611 | 55992584 |
Eye swelling | 13.36 | 10.37 | 170 | 292702 | 21206 | 55977989 |
Apathy | 13.33 | 10.37 | 13 | 292859 | 7941 | 55991254 |
Tumour marker increased | 13.31 | 10.37 | 3 | 292869 | 4290 | 55994905 |
Cholelithiasis | 13.31 | 10.37 | 136 | 292736 | 39328 | 55959867 |
Pyelonephritis | 13.27 | 10.37 | 41 | 292831 | 15983 | 55983212 |
Toothache | 13.27 | 10.37 | 48 | 292824 | 17832 | 55981363 |
Miosis | 13.26 | 10.37 | 9 | 292863 | 6583 | 55992612 |
Neutropenic sepsis | 13.19 | 10.37 | 38 | 292834 | 15147 | 55984048 |
Paraesthesia | 13.15 | 10.37 | 550 | 292322 | 129964 | 55869231 |
Myocardial ischaemia | 13.15 | 10.37 | 27 | 292845 | 12089 | 55987106 |
Pollakiuria | 13.14 | 10.37 | 77 | 292795 | 25125 | 55974070 |
Acute coronary syndrome | 13.13 | 10.37 | 19 | 292853 | 9749 | 55989446 |
Drug ineffective for unapproved indication | 13.13 | 10.37 | 79 | 292793 | 25614 | 55973581 |
Metabolic disorder | 13.08 | 10.37 | 6 | 292866 | 5455 | 55993740 |
Polyuria | 13.06 | 10.37 | 12 | 292860 | 7539 | 55991656 |
Blood glucose decreased | 13.03 | 10.37 | 53 | 292819 | 19034 | 55980161 |
Congestive cardiomyopathy | 13.03 | 10.37 | 7 | 292865 | 5812 | 55993383 |
Cells in urine | 12.98 | 10.37 | 10 | 292862 | 206 | 55998989 |
Nail operation | 12.93 | 10.37 | 18 | 292854 | 759 | 55998436 |
Arterial occlusive disease | 12.87 | 10.37 | 6 | 292866 | 5404 | 55993791 |
Aphthous ulcer | 12.86 | 10.37 | 27 | 292845 | 11992 | 55987203 |
Necrosis | 12.84 | 10.37 | 5 | 292867 | 5011 | 55994184 |
Amylase increased | 12.83 | 10.37 | 7 | 292865 | 5764 | 55993431 |
Lip swelling | 12.82 | 10.37 | 200 | 292672 | 26072 | 55973123 |
Pulmonary congestion | 12.81 | 10.37 | 42 | 292830 | 16073 | 55983122 |
Obstructive airways disorder | 12.81 | 10.37 | 142 | 292730 | 17140 | 55982055 |
Lacrimation increased | 12.81 | 10.37 | 149 | 292723 | 18199 | 55980996 |
Epidermolysis bullosa | 12.79 | 10.37 | 8 | 292864 | 116 | 55999079 |
Blood pressure abnormal | 12.76 | 10.37 | 33 | 292839 | 13627 | 55985568 |
Rash maculo-papular | 12.70 | 10.37 | 93 | 292779 | 28814 | 55970381 |
Intentional self-injury | 12.69 | 10.37 | 77 | 292795 | 24915 | 55974280 |
Post procedural haemorrhage | 12.69 | 10.37 | 12 | 292860 | 7437 | 55991758 |
Pulmonary haemorrhage | 12.68 | 10.37 | 10 | 292862 | 6773 | 55992422 |
Ulcer | 12.65 | 10.37 | 67 | 292805 | 22418 | 55976777 |
Enterocolitis | 12.63 | 10.37 | 11 | 292861 | 7093 | 55992102 |
Sinus disorder | 12.58 | 10.37 | 164 | 292708 | 20570 | 55978625 |
Gait inability | 12.55 | 10.37 | 148 | 292724 | 41670 | 55957525 |
Cachexia | 12.53 | 10.37 | 5 | 292867 | 4937 | 55994258 |
Tardive dyskinesia | 12.48 | 10.37 | 14 | 292858 | 8017 | 55991178 |
Post procedural infection | 12.43 | 10.37 | 15 | 292857 | 8317 | 55990878 |
Device related infection | 12.42 | 10.37 | 65 | 292807 | 21815 | 55977380 |
Leukoencephalopathy | 12.37 | 10.37 | 3 | 292869 | 4079 | 55995116 |
Pneumothorax | 12.34 | 10.37 | 38 | 292834 | 14829 | 55984366 |
Escherichia urinary tract infection | 12.30 | 10.37 | 24 | 292848 | 10951 | 55988244 |
Neurological symptom | 12.25 | 10.37 | 5 | 292867 | 4871 | 55994324 |
Thymus disorder | 12.20 | 10.37 | 11 | 292861 | 284 | 55998911 |
Bronchial disorder | 12.18 | 10.37 | 22 | 292850 | 1161 | 55998034 |
Vertigo CNS origin | 12.18 | 10.37 | 5 | 292867 | 27 | 55999168 |
Epilepsy | 12.16 | 10.37 | 79 | 292793 | 25152 | 55974043 |
Urine amphetamine positive | 12.14 | 10.37 | 6 | 292866 | 53 | 55999142 |
Motor dysfunction | 12.13 | 10.37 | 19 | 292853 | 9438 | 55989757 |
Toxic encephalopathy | 12.09 | 10.37 | 8 | 292864 | 5930 | 55993265 |
Bedridden | 12.08 | 10.37 | 22 | 292850 | 10303 | 55988892 |
Poor venous access | 12.06 | 10.37 | 29 | 292843 | 12277 | 55986918 |
Poisoning | 11.93 | 10.37 | 31 | 292841 | 12782 | 55986413 |
Gastric cancer | 11.93 | 10.37 | 3 | 292869 | 3980 | 55995215 |
Pre-eclampsia | 11.91 | 10.37 | 16 | 292856 | 8470 | 55990725 |
Hyperthyroidism | 11.91 | 10.37 | 33 | 292839 | 13319 | 55985876 |
Glaucoma | 11.90 | 10.37 | 48 | 292824 | 17281 | 55981914 |
Lymphocyte count decreased | 11.90 | 10.37 | 208 | 292664 | 27731 | 55971464 |
Tendonitis | 11.89 | 10.37 | 51 | 292821 | 18046 | 55981149 |
Respiratory tract infection | 11.88 | 10.37 | 125 | 292747 | 35946 | 55963249 |
Diplopia | 11.85 | 10.37 | 60 | 292812 | 20309 | 55978886 |
Delirium | 11.81 | 10.37 | 153 | 292719 | 42364 | 55956831 |
Demyelination | 11.79 | 10.37 | 64 | 292808 | 6198 | 55992997 |
Insomnia | 11.76 | 10.37 | 1155 | 291717 | 190705 | 55808490 |
Lower gastrointestinal haemorrhage | 11.75 | 10.37 | 12 | 292860 | 7175 | 55992020 |
Ovarian germ cell cancer stage II | 11.75 | 10.37 | 5 | 292867 | 30 | 55999165 |
Normochromic normocytic anaemia | 11.70 | 10.37 | 4 | 292868 | 4345 | 55994850 |
Swelling face | 11.68 | 10.37 | 378 | 292494 | 55691 | 55943504 |
Prescribed underdose | 11.65 | 10.37 | 161 | 292711 | 20456 | 55978739 |
Limb injury | 11.63 | 10.37 | 68 | 292804 | 22202 | 55976993 |
Suspected suicide | 11.63 | 10.37 | 7 | 292865 | 5459 | 55993736 |
Eosinophilic granulomatosis with polyangiitis | 11.59 | 10.37 | 30 | 292842 | 2031 | 55997164 |
Hyperplastic cholecystopathy | 11.59 | 10.37 | 7 | 292865 | 95 | 55999100 |
Autophobia | 11.57 | 10.37 | 4 | 292868 | 12 | 55999183 |
Deficiency of bile secretion | 11.57 | 10.37 | 4 | 292868 | 12 | 55999183 |
Lipase increased | 11.55 | 10.37 | 18 | 292854 | 8961 | 55990234 |
Alanine aminotransferase abnormal | 11.55 | 10.37 | 4 | 292868 | 4311 | 55994884 |
Spinal stenosis | 11.51 | 10.37 | 36 | 292836 | 13978 | 55985217 |
Hyperuricaemia | 11.51 | 10.37 | 6 | 292866 | 5067 | 55994128 |
Upper limb fracture | 11.48 | 10.37 | 48 | 292824 | 17107 | 55982088 |
Spinal cord paralysis | 11.48 | 10.37 | 5 | 292867 | 32 | 55999163 |
Metastases to lymph nodes | 11.47 | 10.37 | 13 | 292859 | 7410 | 55991785 |
Osteoporosis | 11.45 | 10.37 | 196 | 292676 | 51856 | 55947339 |
Intervertebral disc degeneration | 11.44 | 10.37 | 37 | 292835 | 14217 | 55984978 |
Soft tissue disorder | 11.41 | 10.37 | 4 | 292868 | 4278 | 55994917 |
Pneumonia bacterial | 11.41 | 10.37 | 15 | 292857 | 8013 | 55991182 |
Hypogammaglobulinaemia | 11.36 | 10.37 | 10 | 292862 | 6416 | 55992779 |
Skin discolouration | 11.34 | 10.37 | 119 | 292753 | 34237 | 55964958 |
Hyperlipidaemia | 11.31 | 10.37 | 52 | 292820 | 18057 | 55981138 |
Polymenorrhoea | 11.31 | 10.37 | 21 | 292851 | 1132 | 55998063 |
Hepatic lesion | 11.29 | 10.37 | 4 | 292868 | 4251 | 55994944 |
Decubitus ulcer | 11.28 | 10.37 | 21 | 292851 | 9754 | 55989441 |
Embolism | 11.26 | 10.37 | 13 | 292859 | 7351 | 55991844 |
Hyperthermia | 11.25 | 10.37 | 16 | 292856 | 8269 | 55990926 |
Feeling abnormal | 11.25 | 10.37 | 574 | 292298 | 133028 | 55866167 |
Tinnitus | 11.20 | 10.37 | 101 | 292771 | 29941 | 55969254 |
Syphilis | 11.16 | 10.37 | 8 | 292864 | 147 | 55999048 |
Dysuria | 11.16 | 10.37 | 104 | 292768 | 30625 | 55968570 |
Haemoglobin abnormal | 11.12 | 10.37 | 5 | 292867 | 4599 | 55994596 |
Eosinophil count increased | 11.09 | 10.37 | 87 | 292785 | 9550 | 55989645 |
Choluria | 11.07 | 10.37 | 8 | 292864 | 149 | 55999046 |
Ileus paralytic | 11.04 | 10.37 | 4 | 292868 | 4191 | 55995004 |
Haemolysis | 11.01 | 10.37 | 10 | 292862 | 6318 | 55992877 |
Oligohydramnios | 11.00 | 10.37 | 9 | 292863 | 5985 | 55993210 |
Acute pulmonary oedema | 11.00 | 10.37 | 14 | 292858 | 7583 | 55991612 |
Uveitis | 10.99 | 10.37 | 26 | 292846 | 11069 | 55988126 |
Oligoarthritis | 10.98 | 10.37 | 12 | 292860 | 393 | 55998802 |
Flank pain | 10.93 | 10.37 | 38 | 292834 | 14287 | 55984908 |
Transfusion | 10.91 | 10.37 | 35 | 292837 | 13485 | 55985710 |
Renal cancer | 10.90 | 10.37 | 7 | 292865 | 5272 | 55993923 |
Bacterial sepsis | 10.89 | 10.37 | 3 | 292869 | 3746 | 55995449 |
Activated partial thromboplastin time prolonged | 10.86 | 10.37 | 11 | 292861 | 6601 | 55992594 |
Blood magnesium decreased | 10.85 | 10.37 | 29 | 292843 | 11845 | 55987350 |
Endometrial ablation | 10.85 | 10.37 | 18 | 292854 | 887 | 55998308 |
Gastrooesophageal reflux disease | 10.84 | 10.37 | 340 | 292532 | 82917 | 55916278 |
Hypomania | 10.82 | 10.37 | 6 | 292866 | 4896 | 55994299 |
Blood pressure inadequately controlled | 10.79 | 10.37 | 5 | 292867 | 4519 | 55994676 |
Musculoskeletal chest pain | 10.78 | 10.37 | 59 | 292813 | 19582 | 55979613 |
Escherichia sepsis | 10.73 | 10.37 | 5 | 292867 | 4504 | 55994691 |
CSF volume increased | 10.73 | 10.37 | 3 | 292869 | 3 | 55999192 |
Scleritis | 10.72 | 10.37 | 3 | 292869 | 3708 | 55995487 |
Epigastric discomfort | 10.72 | 10.37 | 10 | 292862 | 6238 | 55992957 |
Cholecystitis chronic | 10.67 | 10.37 | 87 | 292785 | 9661 | 55989534 |
Atrioventricular block complete | 10.65 | 10.37 | 14 | 292858 | 7480 | 55991715 |
Enterococcal infection | 10.65 | 10.37 | 13 | 292859 | 7171 | 55992024 |
Axillary pain | 10.63 | 10.37 | 26 | 292846 | 1699 | 55997496 |
Affect lability | 10.62 | 10.37 | 23 | 292849 | 10102 | 55989093 |
Pathological fracture | 10.61 | 10.37 | 16 | 292856 | 8073 | 55991122 |
Uterine cancer | 10.61 | 10.37 | 5 | 292867 | 4474 | 55994721 |
Injection site bruising | 10.56 | 10.37 | 139 | 292733 | 38382 | 55960813 |
Nephrogenic systemic fibrosis | 10.55 | 10.37 | 5 | 292867 | 4460 | 55994735 |
Delusion | 10.54 | 10.37 | 27 | 292845 | 11188 | 55988007 |
Myopathy | 10.53 | 10.37 | 22 | 292850 | 9790 | 55989405 |
Inflammation | 10.53 | 10.37 | 276 | 292596 | 68795 | 55930400 |
Wrist fracture | 10.52 | 10.37 | 30 | 292842 | 11996 | 55987199 |
Blood creatine increased | 10.49 | 10.37 | 7 | 292865 | 5166 | 55994029 |
Proctalgia | 10.45 | 10.37 | 8 | 292864 | 5501 | 55993694 |
Presyncope | 10.44 | 10.37 | 84 | 292788 | 25498 | 55973697 |
Immobile | 10.43 | 10.37 | 8 | 292864 | 5494 | 55993701 |
Cyanosis central | 10.43 | 10.37 | 6 | 292866 | 74 | 55999121 |
Nitrite urine present | 10.42 | 10.37 | 19 | 292853 | 1010 | 55998185 |
Red cell distribution width decreased | 10.42 | 10.37 | 25 | 292847 | 1614 | 55997581 |
Joint effusion | 10.40 | 10.37 | 41 | 292831 | 14857 | 55984338 |
Eye disorder | 10.39 | 10.37 | 63 | 292809 | 20389 | 55978806 |
Post procedural complication | 10.38 | 10.37 | 44 | 292828 | 15622 | 55983573 |
Nystagmus | 10.38 | 10.37 | 9 | 292863 | 5816 | 55993379 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Urticaria | 340.55 | 10.45 | 467 | 56691 | 57050 | 31583136 |
Asthma | 271.98 | 10.45 | 359 | 56799 | 42252 | 31597934 |
Pruritus | 236.64 | 10.45 | 623 | 56535 | 124544 | 31515642 |
Dermatitis atopic | 126.09 | 10.45 | 89 | 57069 | 4773 | 31635413 |
Sleep terror | 106.73 | 10.45 | 43 | 57115 | 714 | 31639472 |
Sinusitis | 95.42 | 10.45 | 207 | 56951 | 36489 | 31603697 |
Rash | 92.72 | 10.45 | 651 | 56507 | 200835 | 31439351 |
Infective pulmonary exacerbation of cystic fibrosis | 81.76 | 10.45 | 78 | 57080 | 6406 | 31633780 |
Death | 80.53 | 10.45 | 356 | 56802 | 360213 | 31279973 |
Hypersensitivity | 77.58 | 10.45 | 249 | 56909 | 55494 | 31584692 |
Forced expiratory volume decreased | 73.75 | 10.45 | 53 | 57105 | 2924 | 31637262 |
Upper respiratory tract infection | 69.77 | 10.45 | 160 | 56998 | 29262 | 31610924 |
Wheezing | 68.65 | 10.45 | 180 | 56978 | 35806 | 31604380 |
Vital capacity decreased | 62.22 | 10.45 | 24 | 57134 | 353 | 31639833 |
Anaemia | 60.46 | 10.45 | 191 | 56967 | 213331 | 31426855 |
Lip swelling | 56.94 | 10.45 | 93 | 57065 | 13230 | 31626956 |
Headache | 55.58 | 10.45 | 540 | 56618 | 183112 | 31457074 |
Eczema | 54.58 | 10.45 | 99 | 57059 | 15318 | 31624868 |
Eye disorder | 53.19 | 10.45 | 71 | 57087 | 8431 | 31631755 |
Product dose omission issue | 51.89 | 10.45 | 347 | 56811 | 105239 | 31534947 |
Cough | 50.30 | 10.45 | 415 | 56743 | 134399 | 31505787 |
Pruritus genital | 46.62 | 10.45 | 22 | 57136 | 543 | 31639643 |
Swelling face | 44.95 | 10.45 | 111 | 57047 | 21279 | 31618907 |
Nasal congestion | 43.07 | 10.45 | 106 | 57052 | 20275 | 31619911 |
Angioedema | 43.01 | 10.45 | 146 | 57012 | 33472 | 31606714 |
Lower respiratory tract infection | 42.82 | 10.45 | 130 | 57028 | 28107 | 31612079 |
Parathyroid gland enlargement | 42.57 | 10.45 | 14 | 57144 | 125 | 31640061 |
Potassium wasting nephropathy | 42.17 | 10.45 | 13 | 57145 | 92 | 31640094 |
Upper respiratory fungal infection | 41.43 | 10.45 | 14 | 57144 | 137 | 31640049 |
General physical health deterioration | 40.78 | 10.45 | 90 | 57068 | 113345 | 31526841 |
Multiple organ dysfunction syndrome | 40.42 | 10.45 | 38 | 57120 | 68165 | 31572021 |
Anaphylactic reaction | 40.17 | 10.45 | 131 | 57027 | 29422 | 31610764 |
Dry skin | 39.29 | 10.45 | 118 | 57040 | 25363 | 31614823 |
Fatigue | 39.07 | 10.45 | 833 | 56325 | 334373 | 31305813 |
Sudden infant death syndrome | 37.79 | 10.45 | 14 | 57144 | 183 | 31640003 |
Illness | 37.29 | 10.45 | 63 | 57095 | 9214 | 31630972 |
Chest discomfort | 37.25 | 10.45 | 182 | 56976 | 49187 | 31590999 |
Renal failure | 37.23 | 10.45 | 107 | 57051 | 123223 | 31516963 |
Mydriasis | 36.89 | 10.45 | 52 | 57106 | 6500 | 31633686 |
Migraine | 36.85 | 10.45 | 80 | 57078 | 14100 | 31626086 |
Forced expiratory volume | 36.70 | 10.45 | 12 | 57146 | 105 | 31640081 |
Rheumatoid arthritis | 35.59 | 10.45 | 21 | 57137 | 47788 | 31592398 |
Suicidal ideation | 34.81 | 10.45 | 144 | 57014 | 36262 | 31603924 |
Throat irritation | 34.49 | 10.45 | 61 | 57097 | 9253 | 31630933 |
Renal impairment | 34.00 | 10.45 | 65 | 57093 | 86284 | 31553902 |
Erythema | 33.51 | 10.45 | 254 | 56904 | 80151 | 31560035 |
Throat tightness | 33.40 | 10.45 | 54 | 57104 | 7615 | 31632571 |
Influenza | 33.15 | 10.45 | 163 | 56995 | 44162 | 31596024 |
Crystal urine present | 32.96 | 10.45 | 16 | 57142 | 421 | 31639765 |
Toxicity to various agents | 32.50 | 10.45 | 193 | 56965 | 181294 | 31458892 |
Blood pressure increased | 32.31 | 10.45 | 250 | 56908 | 79383 | 31560803 |
Cardiac failure | 31.04 | 10.45 | 68 | 57090 | 85885 | 31554301 |
Tendon disorder | 30.89 | 10.45 | 30 | 57128 | 2518 | 31637668 |
Penis injury | 30.61 | 10.45 | 13 | 57145 | 248 | 31639938 |
Bronchopulmonary aspergillosis allergic | 30.29 | 10.45 | 17 | 57141 | 607 | 31639579 |
Penile haemorrhage | 30.01 | 10.45 | 17 | 57141 | 618 | 31639568 |
Oral pruritus | 29.65 | 10.45 | 13 | 57145 | 269 | 31639917 |
Pulmonary function test decreased | 29.57 | 10.45 | 38 | 57120 | 4347 | 31635839 |
Flushing | 29.46 | 10.45 | 120 | 57038 | 30008 | 31610178 |
Differentiation syndrome | 28.35 | 10.45 | 21 | 57137 | 1214 | 31638972 |
Anxiety | 28.11 | 10.45 | 269 | 56889 | 90764 | 31549422 |
Seasonal allergy | 28.04 | 10.45 | 42 | 57116 | 5546 | 31634640 |
Obstructive airways disorder | 27.97 | 10.45 | 67 | 57091 | 12597 | 31627589 |
Completed suicide | 27.89 | 10.45 | 79 | 57079 | 91435 | 31548751 |
Nasal oedema | 27.73 | 10.45 | 13 | 57145 | 316 | 31639870 |
Patient elopement | 27.33 | 10.45 | 7 | 57151 | 22 | 31640164 |
Interstitial lung disease | 27.09 | 10.45 | 43 | 57115 | 61360 | 31578826 |
Myocardial infarction | 27.04 | 10.45 | 109 | 57049 | 113345 | 31526841 |
Disturbance in attention | 26.54 | 10.45 | 95 | 57063 | 22355 | 31617831 |
Ascites | 26.54 | 10.45 | 21 | 57137 | 40992 | 31599194 |
Malignant neoplasm progression | 26.51 | 10.45 | 65 | 57093 | 78933 | 31561253 |
Disease progression | 26.19 | 10.45 | 80 | 57078 | 90384 | 31549802 |
Rash pruritic | 25.54 | 10.45 | 98 | 57060 | 23840 | 31616346 |
Rash erythematous | 25.28 | 10.45 | 94 | 57064 | 22533 | 31617653 |
Depressed mood | 24.87 | 10.45 | 79 | 57079 | 17496 | 31622690 |
Drug resistance | 24.59 | 10.45 | 6 | 57152 | 23447 | 31616739 |
Sepsis | 24.40 | 10.45 | 167 | 56991 | 151762 | 31488424 |
Sinus disorder | 24.31 | 10.45 | 42 | 57116 | 6253 | 31633933 |
Acute kidney injury | 24.20 | 10.45 | 357 | 56801 | 279357 | 31360829 |
Ear infection | 24.10 | 10.45 | 51 | 57107 | 8830 | 31631356 |
Malaise | 24.01 | 10.45 | 432 | 56726 | 168079 | 31472107 |
Aplastic anaemia | 24.00 | 10.45 | 52 | 57106 | 9151 | 31631035 |
Anticholinergic syndrome | 23.86 | 10.45 | 18 | 57140 | 1070 | 31639116 |
Infusion related reaction | 23.60 | 10.45 | 158 | 57000 | 47897 | 31592289 |
Infusion site pain | 23.55 | 10.45 | 29 | 57129 | 3177 | 31637009 |
Gastrointestinal haemorrhage | 23.19 | 10.45 | 74 | 57084 | 82475 | 31557711 |
Encephalopathy | 23.15 | 10.45 | 15 | 57143 | 32459 | 31607727 |
Cardiogenic shock | 22.97 | 10.45 | 6 | 57152 | 22402 | 31617784 |
Bone marrow failure | 22.75 | 10.45 | 11 | 57147 | 27997 | 31612189 |
Dry eye | 22.66 | 10.45 | 47 | 57111 | 8025 | 31632161 |
Middle insomnia | 22.65 | 10.45 | 40 | 57118 | 6059 | 31634127 |
Victim of chemical submission | 22.65 | 10.45 | 7 | 57151 | 50 | 31640136 |
Aspirin-exacerbated respiratory disease | 22.60 | 10.45 | 12 | 57146 | 383 | 31639803 |
Anger | 22.50 | 10.45 | 57 | 57101 | 11096 | 31629090 |
Prostate cancer | 22.21 | 10.45 | 21 | 57137 | 37580 | 31602606 |
Hyperleukocytosis | 22.18 | 10.45 | 21 | 57137 | 1708 | 31638478 |
Swollen tongue | 22.17 | 10.45 | 62 | 57096 | 12800 | 31627386 |
Rash macular | 21.72 | 10.45 | 57 | 57101 | 11338 | 31628848 |
Sinus congestion | 21.58 | 10.45 | 35 | 57123 | 4948 | 31635238 |
Chronic spontaneous urticaria | 21.32 | 10.45 | 9 | 57149 | 169 | 31640017 |
Platelet count decreased | 21.06 | 10.45 | 115 | 57043 | 110320 | 31529866 |
Gastric ulcer perforation | 20.88 | 10.45 | 16 | 57142 | 974 | 31639212 |
Mastocytosis | 20.60 | 10.45 | 6 | 57152 | 34 | 31640152 |
Rhinorrhoea | 20.43 | 10.45 | 89 | 57069 | 22923 | 31617263 |
Tic | 20.31 | 10.45 | 21 | 57137 | 1900 | 31638286 |
Cerebral dysgenesis | 20.22 | 10.45 | 5 | 57153 | 13 | 31640173 |
Ocular hyperaemia | 20.04 | 10.45 | 51 | 57107 | 9958 | 31630228 |
Eye pruritus | 19.93 | 10.45 | 34 | 57124 | 5011 | 31635175 |
Drug ineffective | 19.77 | 10.45 | 553 | 56605 | 395020 | 31245166 |
Postmortem blood drug level | 19.52 | 10.45 | 8 | 57150 | 139 | 31640047 |
Nasal polyps | 19.49 | 10.45 | 21 | 57137 | 1992 | 31638194 |
Conjunctivitis | 19.45 | 10.45 | 46 | 57112 | 8577 | 31631609 |
Neurotoxicity | 19.43 | 10.45 | 3 | 57155 | 16223 | 31623963 |
Plasma cell myeloma | 19.36 | 10.45 | 46 | 57112 | 56485 | 31583701 |
Mood altered | 19.35 | 10.45 | 45 | 57113 | 8301 | 31631885 |
Lymphocyte percentage decreased | 19.20 | 10.45 | 21 | 57137 | 2026 | 31638160 |
Seizure | 19.19 | 10.45 | 269 | 56889 | 99499 | 31540687 |
Poverty of speech | 19.04 | 10.45 | 9 | 57149 | 223 | 31639963 |
Sensorimotor disorder | 18.95 | 10.45 | 11 | 57147 | 419 | 31639767 |
Respiratory muscle weakness | 18.93 | 10.45 | 7 | 57151 | 91 | 31640095 |
International normalised ratio increased | 18.71 | 10.45 | 33 | 57125 | 45190 | 31594996 |
Radiation inflammation | 18.56 | 10.45 | 12 | 57146 | 556 | 31639630 |
Cerebral infarction | 18.51 | 10.45 | 12 | 57146 | 25965 | 31614221 |
Disseminated intravascular coagulation | 18.38 | 10.45 | 7 | 57151 | 20530 | 31619656 |
Pancytopenia | 18.30 | 10.45 | 88 | 57070 | 87228 | 31552958 |
Off label use | 17.97 | 10.45 | 483 | 56675 | 346791 | 31293395 |
C-reactive protein increased | 17.96 | 10.45 | 38 | 57120 | 48612 | 31591574 |
Cardiac arrest | 17.95 | 10.45 | 91 | 57067 | 88971 | 31551215 |
Sinus operation | 17.90 | 10.45 | 12 | 57146 | 591 | 31639595 |
Injection site swelling | 17.76 | 10.45 | 49 | 57109 | 10038 | 31630148 |
Oral allergy syndrome | 17.69 | 10.45 | 5 | 57153 | 25 | 31640161 |
Accident | 17.66 | 10.45 | 28 | 57130 | 3883 | 31636303 |
Scratch | 17.41 | 10.45 | 24 | 57134 | 2937 | 31637249 |
Myelosuppression | 17.33 | 10.45 | 3 | 57155 | 14917 | 31625269 |
Injection | 17.25 | 10.45 | 4 | 57154 | 7 | 31640179 |
Skin haemorrhage | 17.17 | 10.45 | 28 | 57130 | 3976 | 31636210 |
Hepatic function abnormal | 17.13 | 10.45 | 30 | 57128 | 41192 | 31598994 |
Bronchospasm | 17.12 | 10.45 | 48 | 57110 | 9924 | 31630262 |
Blister | 17.10 | 10.45 | 79 | 57079 | 20857 | 31619329 |
Pulmonary pain | 16.88 | 10.45 | 13 | 57145 | 797 | 31639389 |
Pleural effusion | 16.59 | 10.45 | 74 | 57084 | 74846 | 31565340 |
COVID-19 | 16.42 | 10.45 | 161 | 56997 | 54660 | 31585526 |
Product quality issue | 16.41 | 10.45 | 65 | 57093 | 16046 | 31624140 |
Specific gravity urine increased | 16.18 | 10.45 | 7 | 57151 | 140 | 31640046 |
Neutrophil percentage increased | 16.17 | 10.45 | 18 | 57140 | 1771 | 31638415 |
Dermatitis exfoliative | 16.15 | 10.45 | 36 | 57122 | 6456 | 31633730 |
Rhinitis | 16.03 | 10.45 | 31 | 57127 | 5033 | 31635153 |
Adenoidal hypertrophy | 15.96 | 10.45 | 7 | 57151 | 145 | 31640041 |
Oropharyngeal pain | 15.75 | 10.45 | 104 | 57054 | 31379 | 31608807 |
Accidental overdose | 15.55 | 10.45 | 70 | 57088 | 18280 | 31621906 |
Swelling | 15.53 | 10.45 | 118 | 57040 | 37240 | 31602946 |
Leukopenia | 15.43 | 10.45 | 53 | 57105 | 57775 | 31582411 |
Dystonia | 15.42 | 10.45 | 47 | 57111 | 10178 | 31630008 |
Drug interaction | 15.40 | 10.45 | 274 | 56884 | 208269 | 31431917 |
Urine analysis abnormal | 15.31 | 10.45 | 18 | 57140 | 1879 | 31638307 |
Micropenis | 14.98 | 10.45 | 5 | 57153 | 47 | 31640139 |
Eosinophilic oesophagitis | 14.88 | 10.45 | 8 | 57150 | 262 | 31639924 |
Septic shock | 14.85 | 10.45 | 65 | 57093 | 66093 | 31574093 |
Bronchial disorder | 14.72 | 10.45 | 15 | 57143 | 1334 | 31638852 |
Blood creatine phosphokinase increased | 14.50 | 10.45 | 34 | 57124 | 41940 | 31598246 |
Sleep apnoea syndrome | 14.28 | 10.45 | 69 | 57089 | 18556 | 31621630 |
Shock | 14.15 | 10.45 | 12 | 57146 | 22633 | 31617553 |
Haemoglobin urine present | 14.11 | 10.45 | 5 | 57153 | 57 | 31640129 |
Skin fissures | 14.09 | 10.45 | 27 | 57131 | 4353 | 31635833 |
Temperature intolerance | 14.06 | 10.45 | 22 | 57136 | 3017 | 31637169 |
Aggression | 13.97 | 10.45 | 115 | 57043 | 37176 | 31603010 |
Reflux nephropathy | 13.96 | 10.45 | 5 | 57153 | 59 | 31640127 |
Tonsillitis | 13.92 | 10.45 | 18 | 57140 | 2072 | 31638114 |
Increased upper airway secretion | 13.91 | 10.45 | 16 | 57142 | 1632 | 31638554 |
Abdominoplasty | 13.89 | 10.45 | 3 | 57155 | 3 | 31640183 |
Crying | 13.88 | 10.45 | 31 | 57127 | 5566 | 31634620 |
Amino acid level decreased | 13.88 | 10.45 | 5 | 57153 | 60 | 31640126 |
Brugada syndrome | 13.83 | 10.45 | 11 | 57147 | 707 | 31639479 |
Fixed eruption | 13.79 | 10.45 | 15 | 57143 | 1438 | 31638748 |
Infusion site swelling | 13.71 | 10.45 | 18 | 57140 | 2103 | 31638083 |
Respiratory failure | 13.68 | 10.45 | 117 | 57041 | 101332 | 31538854 |
Eye swelling | 13.68 | 10.45 | 42 | 57116 | 9134 | 31631052 |
Gastroenteritis viral | 13.63 | 10.45 | 33 | 57125 | 6244 | 31633942 |
Thrombocytopenia | 13.44 | 10.45 | 179 | 56979 | 142568 | 31497618 |
Myocardial oedema | 13.43 | 10.45 | 7 | 57151 | 215 | 31639971 |
Insomnia | 13.43 | 10.45 | 243 | 56915 | 94593 | 31545593 |
Pseudoporphyria | 13.41 | 10.45 | 8 | 57150 | 321 | 31639865 |
Treatment failure | 13.33 | 10.45 | 34 | 57124 | 40758 | 31599428 |
Neuroleptic malignant syndrome | 13.14 | 10.45 | 7 | 57151 | 16862 | 31623324 |
Erythema multiforme | 13.03 | 10.45 | 38 | 57120 | 8033 | 31632153 |
Heart rate increased | 12.93 | 10.45 | 122 | 57036 | 40988 | 31599198 |
Pharyngitis streptococcal | 12.86 | 10.45 | 18 | 57140 | 2235 | 31637951 |
Neutropenia | 12.85 | 10.45 | 177 | 56981 | 140187 | 31499999 |
Periorbital discomfort | 12.55 | 10.45 | 4 | 57154 | 32 | 31640154 |
Peritonitis | 12.48 | 10.45 | 6 | 57152 | 15321 | 31624865 |
Complex regional pain syndrome | 12.37 | 10.45 | 9 | 57149 | 506 | 31639680 |
Irritability | 12.30 | 10.45 | 77 | 57081 | 22812 | 31617374 |
Palpitations | 12.08 | 10.45 | 105 | 57053 | 34478 | 31605708 |
Urethritis noninfective | 12.08 | 10.45 | 3 | 57155 | 8 | 31640178 |
Lymphocyte count decreased | 12.07 | 10.45 | 71 | 57087 | 20578 | 31619608 |
Hypotension | 12.06 | 10.45 | 279 | 56879 | 204339 | 31435847 |
Phonophobia | 11.95 | 10.45 | 6 | 57152 | 170 | 31640016 |
Hypercapnic coma | 11.92 | 10.45 | 6 | 57152 | 171 | 31640015 |
Urine albumin/creatinine ratio | 11.82 | 10.45 | 3 | 57155 | 9 | 31640177 |
Food allergy | 11.82 | 10.45 | 12 | 57146 | 1063 | 31639123 |
Cerebral haemorrhage | 11.80 | 10.45 | 26 | 57132 | 32786 | 31607400 |
Penile erythema | 11.76 | 10.45 | 6 | 57152 | 176 | 31640010 |
Urine ketone body present | 11.73 | 10.45 | 12 | 57146 | 1072 | 31639114 |
Swelling of eyelid | 11.73 | 10.45 | 11 | 57147 | 884 | 31639302 |
Pharyngeal paraesthesia | 11.73 | 10.45 | 9 | 57149 | 549 | 31639637 |
Acute myeloid leukaemia | 11.54 | 10.45 | 10 | 57148 | 18662 | 31621524 |
Amino acid level increased | 11.53 | 10.45 | 8 | 57150 | 417 | 31639769 |
Eye movement disorder | 11.45 | 10.45 | 23 | 57135 | 3838 | 31636348 |
Full blood count abnormal | 11.43 | 10.45 | 59 | 57099 | 16288 | 31623898 |
Hyperventilation | 11.43 | 10.45 | 18 | 57140 | 2483 | 31637703 |
Adenocarcinoma pancreas | 11.42 | 10.45 | 13 | 57145 | 1311 | 31638875 |
Skin exfoliation | 11.42 | 10.45 | 78 | 57080 | 23796 | 31616390 |
Cardiac failure congestive | 11.41 | 10.45 | 90 | 57068 | 79297 | 31560889 |
Respiratory tract infection | 11.33 | 10.45 | 62 | 57096 | 17499 | 31622687 |
Sleep disorder due to a general medical condition | 11.28 | 10.45 | 23 | 57135 | 3879 | 31636307 |
Injection site reaction | 11.06 | 10.45 | 46 | 57112 | 11605 | 31628581 |
Croup infectious | 11.05 | 10.45 | 7 | 57151 | 313 | 31639873 |
Urine abnormality | 11.01 | 10.45 | 15 | 57143 | 1816 | 31638370 |
Congenital genital malformation | 11.00 | 10.45 | 5 | 57153 | 113 | 31640073 |
Post-tussive vomiting | 10.96 | 10.45 | 3 | 57155 | 13 | 31640173 |
Labelled drug-drug interaction medication error | 10.95 | 10.45 | 5 | 57153 | 13158 | 31627028 |
Secretion discharge | 10.77 | 10.45 | 26 | 57132 | 4911 | 31635275 |
Frustration tolerance decreased | 10.76 | 10.45 | 17 | 57141 | 2351 | 31637835 |
Viral infection | 10.71 | 10.45 | 56 | 57102 | 15537 | 31624649 |
Infusion site erythema | 10.68 | 10.45 | 15 | 57143 | 1868 | 31638318 |
Infusion site mass | 10.68 | 10.45 | 7 | 57151 | 332 | 31639854 |
Febrile neutropenia | 10.67 | 10.45 | 155 | 57003 | 121694 | 31518492 |
Deep vein thrombosis | 10.63 | 10.45 | 65 | 57093 | 60671 | 31579515 |
Physiotherapy chest | 10.61 | 10.45 | 3 | 57155 | 15 | 31640171 |
Ventricular fibrillation | 10.58 | 10.45 | 11 | 57147 | 18837 | 31621349 |
Forced expiratory volume increased | 10.45 | 10.45 | 3 | 57155 | 16 | 31640170 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Pemphigus | 1710.95 | 9.99 | 1795 | 256113 | 81241 | 70589295 |
Glossodynia | 1532.82 | 9.99 | 1727 | 256181 | 84760 | 70585776 |
Systemic lupus erythematosus | 1528.72 | 9.99 | 1868 | 256040 | 100034 | 70570502 |
Hand deformity | 1373.24 | 9.99 | 1632 | 256276 | 84850 | 70585686 |
Pericarditis | 1201.35 | 9.99 | 1510 | 256398 | 83195 | 70587341 |
Anti-cyclic citrullinated peptide antibody positive | 1146.35 | 9.99 | 1344 | 256564 | 68841 | 70601695 |
Hypersensitivity | 1136.29 | 9.99 | 2550 | 255358 | 227262 | 70443274 |
Wound | 1096.56 | 9.99 | 1562 | 256346 | 97170 | 70573366 |
Swelling | 1056.35 | 9.99 | 2201 | 255707 | 186338 | 70484198 |
Alopecia | 995.98 | 9.99 | 2216 | 255692 | 196274 | 70474262 |
Urticaria | 971.72 | 9.99 | 1953 | 255955 | 161096 | 70509440 |
Discomfort | 954.07 | 9.99 | 1516 | 256392 | 103920 | 70566616 |
Abdominal discomfort | 914.71 | 9.99 | 2248 | 255660 | 212410 | 70458126 |
Duodenal ulcer perforation | 831.43 | 9.99 | 977 | 256931 | 50135 | 70620401 |
Synovitis | 819.29 | 9.99 | 1589 | 256319 | 127639 | 70542897 |
Pruritus | 811.84 | 9.99 | 2929 | 254979 | 342631 | 70327905 |
Helicobacter infection | 793.25 | 9.99 | 995 | 256913 | 54661 | 70615875 |
Arthropathy | 760.86 | 9.99 | 1683 | 256225 | 148374 | 70522162 |
Blister | 720.45 | 9.99 | 1303 | 256605 | 99223 | 70571313 |
Contraindicated product administered | 709.89 | 9.99 | 1534 | 256374 | 133078 | 70537458 |
Muscle injury | 704.14 | 9.99 | 782 | 257126 | 37712 | 70632824 |
Folliculitis | 696.11 | 9.99 | 816 | 257092 | 41754 | 70628782 |
Irritable bowel syndrome | 677.17 | 9.99 | 879 | 257029 | 49971 | 70620565 |
Hepatic enzyme increased | 671.25 | 9.99 | 1647 | 256261 | 155343 | 70515193 |
Infusion related reaction | 658.53 | 9.99 | 1889 | 256019 | 195645 | 70474891 |
Sleep disorder due to general medical condition, insomnia type | 611.12 | 9.99 | 701 | 257207 | 35031 | 70635505 |
Maternal exposure during pregnancy | 581.38 | 9.99 | 1291 | 256617 | 114054 | 70556482 |
Rash | 574.01 | 9.99 | 3489 | 254419 | 507073 | 70163463 |
Sinusitis | 568.59 | 9.99 | 1623 | 256285 | 167572 | 70502964 |
Lower respiratory tract infection | 551.03 | 9.99 | 1241 | 256667 | 110672 | 70559864 |
Death | 536.59 | 9.99 | 640 | 257268 | 509421 | 70161115 |
Rheumatoid factor positive | 509.51 | 9.99 | 747 | 257161 | 47653 | 70622883 |
Drug intolerance | 487.16 | 9.99 | 1863 | 256045 | 223824 | 70446712 |
Acute kidney injury | 461.26 | 9.99 | 632 | 257276 | 473992 | 70196544 |
Joint swelling | 459.76 | 9.99 | 1981 | 255927 | 251230 | 70419306 |
Toxicity to various agents | 443.08 | 9.99 | 442 | 257466 | 381730 | 70288806 |
Anaemia | 440.38 | 9.99 | 491 | 257417 | 402932 | 70267604 |
Pain | 425.96 | 9.99 | 3809 | 254099 | 625007 | 70045529 |
Therapeutic product effect decreased | 417.83 | 9.99 | 1306 | 256602 | 141712 | 70528824 |
Impaired healing | 392.22 | 9.99 | 848 | 257060 | 73526 | 70597010 |
Rheumatoid arthritis | 376.39 | 9.99 | 2070 | 255838 | 289735 | 70380801 |
Asthma | 352.70 | 9.99 | 1103 | 256805 | 119690 | 70550846 |
Drug interaction | 348.55 | 9.99 | 530 | 257378 | 380911 | 70289625 |
Ill-defined disorder | 339.04 | 9.99 | 667 | 257241 | 54074 | 70616462 |
Completed suicide | 331.83 | 9.99 | 208 | 257700 | 226927 | 70443609 |
Fatigue | 298.10 | 9.99 | 4420 | 253488 | 819899 | 69850637 |
Rheumatic fever | 259.90 | 9.99 | 321 | 257587 | 17339 | 70653197 |
Neutropenia | 253.82 | 9.99 | 338 | 257570 | 256818 | 70413718 |
Product use issue | 250.41 | 9.99 | 1304 | 256604 | 178633 | 70491903 |
Gastrointestinal disorder | 248.56 | 9.99 | 896 | 257012 | 104531 | 70566005 |
Food allergy | 248.12 | 9.99 | 223 | 257685 | 8301 | 70662235 |
Hypotension | 246.09 | 9.99 | 708 | 257200 | 403673 | 70266863 |
Stomatitis | 235.56 | 9.99 | 1009 | 256899 | 127502 | 70543034 |
Hip arthroplasty | 228.66 | 9.99 | 385 | 257523 | 27655 | 70642881 |
Sepsis | 227.78 | 9.99 | 335 | 257573 | 244210 | 70426326 |
Thrombocytopenia | 221.29 | 9.99 | 329 | 257579 | 238781 | 70431755 |
Swollen joint count increased | 209.66 | 9.99 | 254 | 257654 | 13446 | 70657090 |
Knee arthroplasty | 208.79 | 9.99 | 415 | 257493 | 33886 | 70636650 |
Pneumonia | 192.46 | 9.99 | 1324 | 256584 | 594908 | 70075628 |
Nasopharyngitis | 191.68 | 9.99 | 1424 | 256484 | 220782 | 70449754 |
Febrile neutropenia | 188.17 | 9.99 | 282 | 257626 | 204036 | 70466500 |
Fall | 184.44 | 9.99 | 909 | 256999 | 443187 | 70227349 |
Cardiac failure | 180.23 | 9.99 | 154 | 257754 | 143387 | 70527149 |
Multiple organ dysfunction syndrome | 179.28 | 9.99 | 85 | 257823 | 108430 | 70562106 |
Temperature regulation disorder | 178.47 | 9.99 | 140 | 257768 | 4304 | 70666232 |
Myocardial infarction | 175.05 | 9.99 | 220 | 257688 | 171425 | 70499111 |
Renal impairment | 174.02 | 9.99 | 160 | 257748 | 143777 | 70526759 |
Renal failure | 169.26 | 9.99 | 266 | 257642 | 188804 | 70481732 |
Pancytopenia | 167.73 | 9.99 | 181 | 257727 | 150926 | 70519610 |
Coeliac disease | 167.67 | 9.99 | 185 | 257723 | 8848 | 70661688 |
Malignant neoplasm progression | 167.54 | 9.99 | 119 | 257789 | 121620 | 70548916 |
Contusion | 164.49 | 9.99 | 908 | 257000 | 127128 | 70543408 |
Gastrointestinal haemorrhage | 156.53 | 9.99 | 161 | 257747 | 137247 | 70533289 |
Wheezing | 152.63 | 9.99 | 713 | 257195 | 93457 | 70577079 |
Weight increased | 152.01 | 9.99 | 1446 | 256462 | 240885 | 70429651 |
Headache | 148.11 | 9.99 | 2945 | 254963 | 577460 | 70093076 |
Type 2 diabetes mellitus | 147.91 | 9.99 | 423 | 257485 | 43657 | 70626879 |
Hyponatraemia | 146.35 | 9.99 | 222 | 257686 | 159865 | 70510671 |
Septic shock | 142.67 | 9.99 | 119 | 257789 | 112139 | 70558397 |
Disease progression | 142.52 | 9.99 | 218 | 257690 | 156454 | 70514082 |
Respiratory failure | 142.07 | 9.99 | 247 | 257661 | 168488 | 70502048 |
Peripheral swelling | 139.74 | 9.99 | 1394 | 256514 | 235169 | 70435367 |
Interstitial lung disease | 139.28 | 9.99 | 106 | 257802 | 104579 | 70565957 |
Platelet count decreased | 136.73 | 9.99 | 276 | 257632 | 177946 | 70492590 |
Dermatitis atopic | 136.21 | 9.99 | 166 | 257742 | 8841 | 70661695 |
Treatment failure | 132.98 | 9.99 | 939 | 256969 | 143203 | 70527333 |
Cardio-respiratory arrest | 130.08 | 9.99 | 105 | 257803 | 100572 | 70569964 |
Cardiac arrest | 130.04 | 9.99 | 239 | 257669 | 159595 | 70510941 |
Infection | 128.81 | 9.99 | 1251 | 256657 | 209534 | 70461002 |
Blood cholesterol increased | 127.48 | 9.99 | 519 | 257389 | 64085 | 70606451 |
Blood creatinine increased | 127.18 | 9.99 | 202 | 257706 | 142799 | 70527737 |
Angioedema | 126.62 | 9.99 | 529 | 257379 | 66081 | 70604455 |
Rhabdomyolysis | 122.32 | 9.99 | 101 | 257807 | 95659 | 70574877 |
Haemoglobin decreased | 121.08 | 9.99 | 364 | 257544 | 204795 | 70465741 |
Atrial fibrillation | 119.20 | 9.99 | 313 | 257595 | 184035 | 70486501 |
International normalised ratio increased | 119.05 | 9.99 | 73 | 257835 | 80653 | 70589883 |
Cardiac failure congestive | 117.96 | 9.99 | 194 | 257714 | 135263 | 70535273 |
Metabolic acidosis | 115.66 | 9.99 | 63 | 257845 | 74283 | 70596253 |
Leukopenia | 113.46 | 9.99 | 132 | 257776 | 106428 | 70564108 |
Chronic spontaneous urticaria | 108.64 | 9.99 | 61 | 257847 | 1050 | 70669486 |
Arthralgia | 105.68 | 9.99 | 2484 | 255424 | 500906 | 70169630 |
Crystal urine present | 102.93 | 9.99 | 74 | 257834 | 1988 | 70668548 |
Drug resistance | 102.59 | 9.99 | 10 | 257898 | 38180 | 70632356 |
Depressed level of consciousness | 102.35 | 9.99 | 100 | 257808 | 87331 | 70583205 |
Night sweats | 100.95 | 9.99 | 369 | 257539 | 43315 | 70627221 |
Bone marrow failure | 100.30 | 9.99 | 27 | 257881 | 48983 | 70621553 |
Plasma cell myeloma | 98.81 | 9.99 | 73 | 257835 | 73128 | 70597408 |
Hyperkalaemia | 96.25 | 9.99 | 149 | 257759 | 106442 | 70564094 |
Hepatic function abnormal | 95.47 | 9.99 | 65 | 257843 | 67931 | 70602605 |
Ear pain | 92.73 | 9.99 | 265 | 257643 | 27334 | 70643202 |
Ascites | 90.35 | 9.99 | 68 | 257840 | 67479 | 70603057 |
Pleural effusion | 90.19 | 9.99 | 220 | 257688 | 132644 | 70537892 |
Infective pulmonary exacerbation of cystic fibrosis | 90.04 | 9.99 | 160 | 257748 | 11998 | 70658538 |
Hypoglycaemia | 89.99 | 9.99 | 127 | 257781 | 94237 | 70576299 |
Diarrhoea | 86.53 | 9.99 | 2179 | 255729 | 781162 | 69889374 |
Injury | 83.26 | 9.99 | 462 | 257446 | 64783 | 70605753 |
Bursitis | 80.93 | 9.99 | 247 | 257661 | 26426 | 70644110 |
Rash erythematous | 80.43 | 9.99 | 387 | 257521 | 51331 | 70619205 |
Dehydration | 80.40 | 9.99 | 487 | 257421 | 225655 | 70444881 |
Blood creatine phosphokinase increased | 80.25 | 9.99 | 63 | 257845 | 61200 | 70609336 |
Electric shock | 78.95 | 9.99 | 51 | 257857 | 1144 | 70669392 |
Pneumonia aspiration | 77.94 | 9.99 | 67 | 257841 | 62222 | 70608314 |
Immunodeficiency | 77.86 | 9.99 | 187 | 257721 | 17368 | 70653168 |
Shock | 77.73 | 9.99 | 25 | 257883 | 40400 | 70630136 |
Lactic acidosis | 77.70 | 9.99 | 73 | 257835 | 64951 | 70605585 |
White blood cells urine positive | 77.38 | 9.99 | 99 | 257809 | 5541 | 70664995 |
Swelling face | 76.46 | 9.99 | 441 | 257467 | 62723 | 70607813 |
Anaphylactic reaction | 75.99 | 9.99 | 500 | 257408 | 74474 | 70596062 |
Haemorrhage | 75.82 | 9.99 | 117 | 257791 | 83698 | 70586838 |
Cytomegalovirus infection | 75.72 | 9.99 | 25 | 257883 | 39733 | 70630803 |
Urinary sediment present | 75.51 | 9.99 | 65 | 257843 | 2282 | 70668254 |
Haematuria | 75.23 | 9.99 | 72 | 257836 | 63501 | 70607035 |
Urine abnormality | 73.94 | 9.99 | 115 | 257793 | 7723 | 70662813 |
Throat irritation | 73.13 | 9.99 | 288 | 257620 | 35016 | 70635520 |
Muscle spasticity | 73.02 | 9.99 | 196 | 257712 | 19493 | 70651043 |
Lymphocyte percentage decreased | 72.14 | 9.99 | 88 | 257820 | 4691 | 70665845 |
Cerebrovascular accident | 71.36 | 9.99 | 274 | 257634 | 143196 | 70527340 |
Cardiogenic shock | 70.62 | 9.99 | 22 | 257886 | 36285 | 70634251 |
Encephalopathy | 70.47 | 9.99 | 72 | 257836 | 61589 | 70608947 |
Haemoglobin urine present | 69.91 | 9.99 | 42 | 257866 | 825 | 70669711 |
Coma | 69.74 | 9.99 | 143 | 257765 | 91701 | 70578835 |
Acute myeloid leukaemia | 69.35 | 9.99 | 14 | 257894 | 30926 | 70639610 |
Prostate cancer | 68.00 | 9.99 | 15 | 257893 | 31148 | 70639388 |
Disseminated intravascular coagulation | 67.83 | 9.99 | 19 | 257889 | 33579 | 70636957 |
Adverse event | 67.68 | 9.99 | 357 | 257551 | 49104 | 70621432 |
Respiratory disorder | 67.65 | 9.99 | 302 | 257606 | 38821 | 70631715 |
Respiratory arrest | 67.49 | 9.99 | 58 | 257850 | 53875 | 70616661 |
Neurotoxicity | 65.81 | 9.99 | 14 | 257894 | 29812 | 70640724 |
Melaena | 65.32 | 9.99 | 65 | 257843 | 56290 | 70614246 |
Eczema | 64.74 | 9.99 | 269 | 257639 | 33512 | 70637024 |
Acute myocardial infarction | 64.73 | 9.99 | 103 | 257805 | 72784 | 70597752 |
Forced expiratory volume decreased | 64.43 | 9.99 | 104 | 257804 | 7210 | 70663326 |
Overdose | 64.35 | 9.99 | 358 | 257550 | 169387 | 70501149 |
Prescribed overdose | 63.98 | 9.99 | 231 | 257677 | 26950 | 70643586 |
Hepatic failure | 63.93 | 9.99 | 69 | 257839 | 57556 | 70612980 |
Sleep terror | 63.87 | 9.99 | 45 | 257863 | 1170 | 70669366 |
Serotonin syndrome | 63.61 | 9.99 | 37 | 257871 | 42077 | 70628459 |
Temperature intolerance | 63.57 | 9.99 | 114 | 257794 | 8609 | 70661927 |
Victim of chemical submission | 63.30 | 9.99 | 31 | 257877 | 397 | 70670139 |
Maternal exposure timing unspecified | 63.29 | 9.99 | 79 | 257829 | 4312 | 70666224 |
Fibromyalgia | 63.09 | 9.99 | 342 | 257566 | 47532 | 70623004 |
Anticipatory anxiety | 62.04 | 9.99 | 41 | 257867 | 957 | 70669579 |
Drug abuse | 60.61 | 9.99 | 302 | 257606 | 146954 | 70523582 |
Urine analysis abnormal | 60.45 | 9.99 | 92 | 257816 | 6062 | 70664474 |
Type I hypersensitivity | 60.07 | 9.99 | 71 | 257837 | 3661 | 70666875 |
Skin ulcer | 59.97 | 9.99 | 52 | 257856 | 48093 | 70622443 |
Blood bilirubin increased | 59.75 | 9.99 | 78 | 257830 | 59823 | 70610713 |
Neutrophil percentage increased | 59.61 | 9.99 | 78 | 257830 | 4464 | 70666072 |
Red blood cells urine positive | 57.40 | 9.99 | 78 | 257830 | 4631 | 70665905 |
Haematochezia | 57.01 | 9.99 | 112 | 257796 | 72969 | 70597567 |
Lip dry | 56.68 | 9.99 | 116 | 257792 | 9669 | 70660867 |
Adverse drug reaction | 56.65 | 9.99 | 360 | 257548 | 52984 | 70617552 |
Urine leukocyte esterase positive | 56.46 | 9.99 | 68 | 257840 | 3577 | 70666959 |
Lip swelling | 55.99 | 9.99 | 259 | 257649 | 33795 | 70636741 |
Cerebral haemorrhage | 55.95 | 9.99 | 68 | 257840 | 53796 | 70616740 |
Body temperature increased | 55.52 | 9.99 | 289 | 257619 | 39545 | 70630991 |
Retinitis | 55.47 | 9.99 | 72 | 257836 | 4088 | 70666448 |
Hypercalcaemia | 55.15 | 9.99 | 28 | 257880 | 34357 | 70636179 |
Hypokalaemia | 54.59 | 9.99 | 268 | 257640 | 130920 | 70539616 |
Eye pruritus | 54.51 | 9.99 | 146 | 257762 | 14501 | 70656035 |
Cerebral infarction | 54.12 | 9.99 | 46 | 257862 | 42963 | 70627573 |
Myelosuppression | 53.93 | 9.99 | 21 | 257887 | 30124 | 70640412 |
Exposure during pregnancy | 53.69 | 9.99 | 521 | 257387 | 87196 | 70583340 |
Renal tubular necrosis | 52.95 | 9.99 | 10 | 257898 | 23161 | 70647375 |
Pregnancy | 52.53 | 9.99 | 198 | 257710 | 23583 | 70646953 |
Pulmonary oedema | 52.16 | 9.99 | 141 | 257767 | 82137 | 70588399 |
White blood cell count decreased | 52.11 | 9.99 | 383 | 257525 | 169758 | 70500778 |
Orthostatic hypotension | 50.97 | 9.99 | 68 | 257840 | 51675 | 70618861 |
Urinary tract infection | 50.53 | 9.99 | 620 | 257288 | 248149 | 70422387 |
Erythema | 50.42 | 9.99 | 1012 | 256896 | 198551 | 70471985 |
Osteonecrosis of jaw | 50.21 | 9.99 | 45 | 257863 | 40957 | 70629579 |
Mental status changes | 49.83 | 9.99 | 96 | 257812 | 63005 | 70607531 |
Neutrophil count decreased | 49.42 | 9.99 | 148 | 257760 | 83408 | 70587128 |
Ear infection | 49.19 | 9.99 | 219 | 257689 | 28117 | 70642419 |
Live birth | 48.93 | 9.99 | 135 | 257773 | 13644 | 70656892 |
Abdominal pain upper | 48.65 | 9.99 | 981 | 256927 | 192621 | 70477915 |
Oral pruritus | 48.56 | 9.99 | 47 | 257861 | 1924 | 70668612 |
Upper gastrointestinal haemorrhage | 48.50 | 9.99 | 39 | 257869 | 37438 | 70633098 |
Neuroleptic malignant syndrome | 48.40 | 9.99 | 17 | 257891 | 25990 | 70644546 |
Rectal haemorrhage | 47.88 | 9.99 | 105 | 257803 | 65726 | 70604810 |
Musculoskeletal stiffness | 47.79 | 9.99 | 779 | 257129 | 146981 | 70523555 |
Altered state of consciousness | 47.73 | 9.99 | 45 | 257863 | 39977 | 70630559 |
Mechanical urticaria | 47.68 | 9.99 | 25 | 257883 | 373 | 70670163 |
Facet joint syndrome | 47.28 | 9.99 | 82 | 257826 | 6031 | 70664505 |
Adjustment disorder with depressed mood | 47.07 | 9.99 | 67 | 257841 | 4156 | 70666380 |
Ventricular tachycardia | 47.01 | 9.99 | 38 | 257870 | 36385 | 70634151 |
Loss of consciousness | 46.98 | 9.99 | 352 | 257556 | 155364 | 70515172 |
Blood pressure fluctuation | 46.41 | 9.99 | 90 | 257818 | 58922 | 70611614 |
Pericardial effusion | 46.36 | 9.99 | 50 | 257858 | 41726 | 70628810 |
Hyperglycaemia | 46.34 | 9.99 | 104 | 257804 | 64568 | 70605968 |
Vomiting | 46.32 | 9.99 | 1727 | 256181 | 591384 | 70079152 |
Labelled drug-drug interaction medication error | 46.25 | 9.99 | 15 | 257893 | 24112 | 70646424 |
Liver injury | 46.12 | 9.99 | 281 | 257627 | 40754 | 70629782 |
Pneumocystis jirovecii pneumonia | 46.04 | 9.99 | 26 | 257882 | 30056 | 70640480 |
Peritonitis | 45.53 | 9.99 | 19 | 257889 | 26140 | 70644396 |
Shock haemorrhagic | 45.47 | 9.99 | 6 | 257902 | 18100 | 70652436 |
Inappropriate antidiuretic hormone secretion | 45.46 | 9.99 | 14 | 257894 | 23262 | 70647274 |
Blood immunoglobulin E increased | 45.30 | 9.99 | 70 | 257838 | 4674 | 70665862 |
Hypocalcaemia | 45.16 | 9.99 | 58 | 257850 | 44801 | 70625735 |
Neoplasm progression | 45.00 | 9.99 | 59 | 257849 | 45169 | 70625367 |
Insomnia | 44.37 | 9.99 | 1071 | 256837 | 216735 | 70453801 |
Anti-cyclic citrullinated peptide antibody | 44.22 | 9.99 | 58 | 257850 | 3327 | 70667209 |
Mastocytosis | 44.18 | 9.99 | 25 | 257883 | 437 | 70670099 |
Liver function test abnormal | 44.08 | 9.99 | 98 | 257810 | 61048 | 70609488 |
Urticaria chronic | 43.81 | 9.99 | 26 | 257882 | 499 | 70670037 |
Blood lactate dehydrogenase increased | 43.68 | 9.99 | 38 | 257870 | 35089 | 70635447 |
Post-traumatic stress disorder | 43.45 | 9.99 | 66 | 257842 | 4341 | 70666195 |
Bacteraemia | 42.51 | 9.99 | 27 | 257881 | 29282 | 70641254 |
Thrombotic microangiopathy | 42.32 | 9.99 | 7 | 257901 | 17841 | 70652695 |
Chest discomfort | 42.19 | 9.99 | 661 | 257247 | 123720 | 70546816 |
Intentional product use issue | 42.10 | 9.99 | 642 | 257266 | 119500 | 70551036 |
Posterior reversible encephalopathy syndrome | 42.03 | 9.99 | 18 | 257890 | 24384 | 70646152 |
Upper respiratory tract infection | 41.91 | 9.99 | 457 | 257451 | 78817 | 70591719 |
Unresponsive to stimuli | 41.89 | 9.99 | 78 | 257830 | 51853 | 70618683 |
Chronic sinusitis | 41.84 | 9.99 | 94 | 257814 | 8357 | 70662179 |
Oedema peripheral | 41.71 | 9.99 | 581 | 257327 | 227510 | 70443026 |
Thrombosis | 40.79 | 9.99 | 139 | 257769 | 75266 | 70595270 |
Hereditary angioedema | 40.62 | 9.99 | 69 | 257839 | 4990 | 70665546 |
Respiratory depression | 40.15 | 9.99 | 20 | 257888 | 24811 | 70645725 |
Skin plaque | 39.98 | 9.99 | 101 | 257807 | 9682 | 70660854 |
Perfume sensitivity | 39.91 | 9.99 | 28 | 257880 | 723 | 70669813 |
Asthenia | 39.74 | 9.99 | 1315 | 256593 | 456351 | 70214185 |
Agranulocytosis | 39.65 | 9.99 | 53 | 257855 | 40245 | 70630291 |
Premature delivery | 39.52 | 9.99 | 14 | 257894 | 21290 | 70649246 |
Bradycardia | 39.37 | 9.99 | 278 | 257630 | 124337 | 70546199 |
Seasonal allergy | 39.17 | 9.99 | 123 | 257785 | 13361 | 70657175 |
Acute respiratory distress syndrome | 38.85 | 9.99 | 56 | 257852 | 41198 | 70629338 |
Mucosal inflammation | 38.83 | 9.99 | 122 | 257786 | 67728 | 70602808 |
Myelodysplastic syndrome | 38.54 | 9.99 | 31 | 257877 | 29754 | 70640782 |
Transaminases increased | 38.48 | 9.99 | 70 | 257838 | 46948 | 70623588 |
Ileus | 38.48 | 9.99 | 20 | 257888 | 24217 | 70646319 |
Dislocation of vertebra | 38.25 | 9.99 | 66 | 257842 | 4834 | 70665702 |
Dry mouth | 38.09 | 9.99 | 408 | 257500 | 70049 | 70600487 |
Ventricular fibrillation | 37.94 | 9.99 | 26 | 257882 | 27085 | 70643451 |
Alanine aminotransferase increased | 37.85 | 9.99 | 348 | 257560 | 147132 | 70523404 |
Scratch | 37.73 | 9.99 | 82 | 257826 | 7128 | 70663408 |
Psychotic disorder | 37.69 | 9.99 | 49 | 257859 | 37652 | 70632884 |
Off label use | 37.59 | 9.99 | 2266 | 255642 | 740794 | 69929742 |
Intentional overdose | 37.07 | 9.99 | 208 | 257700 | 98227 | 70572309 |
Nausea | 36.77 | 9.99 | 2636 | 255272 | 849452 | 69821084 |
Pruritus genital | 36.68 | 9.99 | 31 | 257877 | 1061 | 70669475 |
Hepatotoxicity | 36.43 | 9.99 | 65 | 257843 | 43921 | 70626615 |
Lacrimation increased | 36.22 | 9.99 | 156 | 257752 | 19743 | 70650793 |
Eye swelling | 36.20 | 9.99 | 176 | 257732 | 23438 | 70647098 |
Decreased appetite | 36.15 | 9.99 | 838 | 257070 | 303942 | 70366594 |
Throat tightness | 35.88 | 9.99 | 183 | 257725 | 24839 | 70645697 |
Pulmonary embolism | 35.72 | 9.99 | 378 | 257530 | 155489 | 70515047 |
Deep vein thrombosis postoperative | 35.54 | 9.99 | 54 | 257854 | 3553 | 70666983 |
Chronic kidney disease | 35.50 | 9.99 | 109 | 257799 | 60948 | 70609588 |
Coronary artery disease | 35.07 | 9.99 | 114 | 257794 | 62622 | 70607914 |
Proteinuria | 35.06 | 9.99 | 33 | 257875 | 29341 | 70641195 |
Status epilepticus | 35.02 | 9.99 | 23 | 257885 | 24503 | 70646033 |
Obstructive airways disorder | 34.71 | 9.99 | 187 | 257721 | 25926 | 70644610 |
Mast cell activation syndrome | 34.71 | 9.99 | 24 | 257884 | 605 | 70669931 |
C-reactive protein increased | 34.69 | 9.99 | 247 | 257661 | 110270 | 70560266 |
Anuria | 34.65 | 9.99 | 14 | 257894 | 19639 | 70650897 |
Cellulitis | 34.62 | 9.99 | 214 | 257694 | 98714 | 70571822 |
Paraesthesia oral | 34.58 | 9.99 | 129 | 257779 | 15288 | 70655248 |
Creatinine renal clearance decreased | 34.22 | 9.99 | 10 | 257898 | 17190 | 70653346 |
Osteomyelitis | 33.96 | 9.99 | 36 | 257872 | 30282 | 70640254 |
Drug level increased | 33.85 | 9.99 | 50 | 257858 | 36419 | 70634117 |
Palmar-plantar erythrodysaesthesia syndrome | 33.79 | 9.99 | 36 | 257872 | 30211 | 70640325 |
Haematemesis | 33.73 | 9.99 | 80 | 257828 | 48717 | 70621819 |
Transplant rejection | 33.61 | 9.99 | 12 | 257896 | 18159 | 70652377 |
Lymphocyte count decreased | 33.55 | 9.99 | 272 | 257636 | 43267 | 70627269 |
Oliguria | 33.34 | 9.99 | 7 | 257901 | 15044 | 70655492 |
Haematotoxicity | 33.24 | 9.99 | 5 | 257903 | 13669 | 70656867 |
Laryngitis | 33.06 | 9.99 | 117 | 257791 | 13514 | 70657022 |
Left ventricular dysfunction | 32.97 | 9.99 | 12 | 257896 | 17945 | 70652591 |
Allergic reaction to excipient | 32.89 | 9.99 | 18 | 257890 | 294 | 70670242 |
Product prescribing error | 32.77 | 9.99 | 57 | 257851 | 38895 | 70631641 |
Renal injury | 32.68 | 9.99 | 9 | 257899 | 16085 | 70654451 |
Nasal congestion | 32.63 | 9.99 | 374 | 257534 | 65298 | 70605238 |
Constipation | 32.53 | 9.99 | 685 | 257223 | 251753 | 70418783 |
Basal cell carcinoma | 32.47 | 9.99 | 45 | 257863 | 33653 | 70636883 |
Electrolyte imbalance | 32.27 | 9.99 | 30 | 257878 | 26831 | 70643705 |
Cardiomyopathy | 32.22 | 9.99 | 29 | 257879 | 26344 | 70644192 |
Neonatal hypoacusis | 32.10 | 9.99 | 9 | 257899 | 17 | 70670519 |
Aspartate aminotransferase increased | 31.99 | 9.99 | 301 | 257607 | 126677 | 70543859 |
Acute hepatic failure | 31.97 | 9.99 | 32 | 257876 | 27640 | 70642896 |
Bacterial test positive | 31.29 | 9.99 | 75 | 257833 | 6956 | 70663580 |
Haemodialysis | 31.22 | 9.99 | 12 | 257896 | 17354 | 70653182 |
Auditory neuropathy spectrum disorder | 31.13 | 9.99 | 9 | 257899 | 20 | 70670516 |
Head deformity | 31.08 | 9.99 | 10 | 257898 | 36 | 70670500 |
Syncope | 31.03 | 9.99 | 420 | 257488 | 165289 | 70505247 |
Colitis | 30.99 | 9.99 | 123 | 257785 | 63691 | 70606845 |
Restrictive pulmonary disease | 30.88 | 9.99 | 40 | 257868 | 2266 | 70668270 |
Sleep disorder | 30.81 | 9.99 | 389 | 257519 | 69483 | 70601053 |
Sudden infant death syndrome | 30.77 | 9.99 | 15 | 257893 | 190 | 70670346 |
Arrhythmia | 30.70 | 9.99 | 103 | 257805 | 56040 | 70614496 |
Autoimmune disorder | 30.68 | 9.99 | 85 | 257823 | 8611 | 70661925 |
Extrapyramidal disorder | 30.26 | 9.99 | 19 | 257889 | 20731 | 70649805 |
Neoplasm malignant | 30.23 | 9.99 | 36 | 257872 | 28738 | 70641798 |
Intentional product misuse | 30.07 | 9.99 | 168 | 257740 | 79427 | 70591109 |
Tachypnoea | 29.90 | 9.99 | 36 | 257872 | 28602 | 70641934 |
Escherichia infection | 29.84 | 9.99 | 11 | 257897 | 16320 | 70654216 |
Metastases to liver | 29.81 | 9.99 | 30 | 257878 | 25848 | 70644688 |
Pathogen resistance | 29.78 | 9.99 | 6 | 257902 | 13273 | 70657263 |
Penis injury | 29.72 | 9.99 | 13 | 257895 | 126 | 70670410 |
Pregnancy on contraceptive | 29.67 | 9.99 | 25 | 257883 | 852 | 70669684 |
Cardiotoxicity | 29.47 | 9.99 | 3 | 257905 | 11067 | 70659469 |
Metastases to central nervous system | 29.43 | 9.99 | 9 | 257899 | 15025 | 70655511 |
Subdural haematoma | 29.37 | 9.99 | 38 | 257870 | 29260 | 70641276 |
Urticaria thermal | 29.36 | 9.99 | 16 | 257892 | 259 | 70670277 |
Localised infection | 29.30 | 9.99 | 47 | 257861 | 33111 | 70637425 |
Psoriatic arthropathy | 29.16 | 9.99 | 362 | 257546 | 64409 | 70606127 |
Drug use disorder | 29.08 | 9.99 | 80 | 257828 | 8071 | 70662465 |
Epistaxis | 29.07 | 9.99 | 236 | 257672 | 102391 | 70568145 |
Leukocytosis | 29.07 | 9.99 | 63 | 257845 | 39605 | 70630931 |
Exposure via body fluid | 28.99 | 9.99 | 16 | 257892 | 266 | 70670270 |
Vocal cord dysfunction | 28.77 | 9.99 | 19 | 257889 | 443 | 70670093 |
Gastric haemorrhage | 28.67 | 9.99 | 8 | 257900 | 14177 | 70656359 |
Haematoma | 28.46 | 9.99 | 86 | 257822 | 48332 | 70622204 |
Parathyroid gland enlargement | 28.36 | 9.99 | 13 | 257895 | 142 | 70670394 |
Neuropathy peripheral | 28.17 | 9.99 | 310 | 257598 | 126586 | 70543950 |
Hypoxia | 28.15 | 9.99 | 211 | 257697 | 93133 | 70577403 |
Skin necrosis | 28.08 | 9.99 | 12 | 257896 | 16279 | 70654257 |
Fracture | 28.08 | 9.99 | 19 | 257889 | 19925 | 70650611 |
Hip fracture | 27.98 | 9.99 | 37 | 257871 | 28226 | 70642310 |
Diffuse large B-cell lymphoma | 27.84 | 9.99 | 7 | 257901 | 13295 | 70657241 |
Pulmonary hypertension | 27.82 | 9.99 | 82 | 257826 | 46454 | 70624082 |
Hypoaesthesia | 27.76 | 9.99 | 744 | 257164 | 152995 | 70517541 |
Oral allergy syndrome | 27.69 | 9.99 | 10 | 257898 | 55 | 70670481 |
Coagulopathy | 27.66 | 9.99 | 49 | 257859 | 33200 | 70637336 |
Graft versus host disease | 27.65 | 9.99 | 10 | 257898 | 15013 | 70655523 |
Hyper IgE syndrome | 27.51 | 9.99 | 19 | 257889 | 478 | 70670058 |
Sedation | 27.47 | 9.99 | 83 | 257825 | 46648 | 70623888 |
Generalised tonic-clonic seizure | 27.46 | 9.99 | 70 | 257838 | 41591 | 70628945 |
Hepatic encephalopathy | 27.41 | 9.99 | 24 | 257884 | 22094 | 70648442 |
Blood urea increased | 27.37 | 9.99 | 81 | 257827 | 45828 | 70624708 |
Intervertebral discitis | 27.33 | 9.99 | 52 | 257856 | 4109 | 70666427 |
Potassium wasting nephropathy | 27.22 | 9.99 | 13 | 257895 | 157 | 70670379 |
Tuberculosis | 27.13 | 9.99 | 10 | 257898 | 14838 | 70655698 |
Grip strength decreased | 27.05 | 9.99 | 121 | 257787 | 15564 | 70654972 |
Gamma-glutamyltransferase increased | 27.03 | 9.99 | 94 | 257814 | 50591 | 70619945 |
Cardiac failure acute | 26.93 | 9.99 | 15 | 257893 | 17472 | 70653064 |
Immune reconstitution inflammatory syndrome | 26.87 | 9.99 | 7 | 257901 | 12983 | 70657553 |
Forced expiratory volume | 26.87 | 9.99 | 11 | 257897 | 89 | 70670447 |
Hyperammonaemia | 26.86 | 9.99 | 3 | 257905 | 10290 | 70660246 |
Sinus disorder | 26.73 | 9.99 | 138 | 257770 | 18821 | 70651715 |
Dialysis | 26.69 | 9.99 | 15 | 257893 | 17387 | 70653149 |
Aspergillus infection | 26.55 | 9.99 | 16 | 257892 | 17852 | 70652684 |
Cestode infection | 26.47 | 9.99 | 15 | 257893 | 263 | 70670273 |
Hallucination, auditory | 26.42 | 9.99 | 17 | 257891 | 18311 | 70652225 |
Enthesopathy | 26.36 | 9.99 | 4 | 257904 | 10865 | 70659671 |
Gastric ulcer | 26.31 | 9.99 | 47 | 257861 | 31743 | 70638793 |
Weight decreased | 26.23 | 9.99 | 895 | 257013 | 309593 | 70360943 |
Hyperbilirubinaemia | 26.18 | 9.99 | 26 | 257882 | 22542 | 70647994 |
Lichen sclerosus | 26.17 | 9.99 | 24 | 257884 | 917 | 70669619 |
Nasal turbinate hypertrophy | 26.17 | 9.99 | 20 | 257888 | 591 | 70669945 |
Haemorrhage intracranial | 26.03 | 9.99 | 31 | 257877 | 24746 | 70645790 |
Victim of sexual abuse | 25.99 | 9.99 | 18 | 257890 | 455 | 70670081 |
Muscle rigidity | 25.94 | 9.99 | 18 | 257890 | 18632 | 70651904 |
Ejection fraction decreased | 25.89 | 9.99 | 45 | 257863 | 30717 | 70639819 |
Metastases to bone | 25.71 | 9.99 | 26 | 257882 | 22350 | 70648186 |
Angina pectoris | 25.62 | 9.99 | 90 | 257818 | 48293 | 70622243 |
Klebsiella infection | 25.49 | 9.99 | 10 | 257898 | 14282 | 70656254 |
Tumour lysis syndrome | 25.49 | 9.99 | 24 | 257884 | 21336 | 70649200 |
Diabetes mellitus | 25.32 | 9.99 | 155 | 257753 | 71669 | 70598867 |
Therapy partial responder | 25.28 | 9.99 | 7 | 257901 | 12467 | 70658069 |
Femur fracture | 25.16 | 9.99 | 59 | 257849 | 36073 | 70634463 |
Herpes zoster | 25.07 | 9.99 | 194 | 257714 | 85041 | 70585495 |
Circulatory collapse | 24.64 | 9.99 | 58 | 257850 | 35416 | 70635120 |
Myoclonus | 24.59 | 9.99 | 36 | 257872 | 26319 | 70644217 |
Allergy test positive | 24.57 | 9.99 | 17 | 257891 | 429 | 70670107 |
Peripheral venous disease | 24.45 | 9.99 | 90 | 257818 | 10597 | 70659939 |
Urinary retention | 24.40 | 9.99 | 103 | 257805 | 52417 | 70618119 |
Respiratory distress | 24.27 | 9.99 | 109 | 257799 | 54541 | 70615995 |
Diabetic ketoacidosis | 23.97 | 9.99 | 49 | 257859 | 31463 | 70639073 |
Middle insomnia | 23.93 | 9.99 | 108 | 257800 | 13945 | 70656591 |
Hypervolaemia | 23.71 | 9.99 | 70 | 257838 | 39636 | 70630900 |
Pulmonary pain | 23.65 | 9.99 | 44 | 257864 | 3418 | 70667118 |
Cystic fibrosis pancreatic | 23.60 | 9.99 | 9 | 257899 | 59 | 70670477 |
Panniculitis | 23.58 | 9.99 | 5 | 257903 | 10671 | 70659865 |
Bronchial neoplasm | 23.57 | 9.99 | 17 | 257891 | 459 | 70670077 |
Second primary malignancy | 23.50 | 9.99 | 9 | 257899 | 13042 | 70657494 |
Encephalitis | 23.43 | 9.99 | 10 | 257898 | 13575 | 70656961 |
Ischaemic stroke | 23.38 | 9.99 | 48 | 257860 | 30772 | 70639764 |
Haemodynamic instability | 23.30 | 9.99 | 14 | 257894 | 15644 | 70654892 |
Substance abuse | 23.01 | 9.99 | 4 | 257904 | 9833 | 70660703 |
Blood potassium increased | 22.97 | 9.99 | 40 | 257868 | 27286 | 70643250 |
Seizure | 22.88 | 9.99 | 483 | 257425 | 177479 | 70493057 |
Cytomegalovirus viraemia | 22.87 | 9.99 | 7 | 257901 | 11678 | 70658858 |
Heparin-induced thrombocytopenia | 22.68 | 9.99 | 3 | 257905 | 9034 | 70661502 |
Blood pressure decreased | 22.59 | 9.99 | 218 | 257690 | 91297 | 70579239 |
Menstruation delayed | 22.51 | 9.99 | 25 | 257883 | 1204 | 70669332 |
Hepatic cancer | 22.51 | 9.99 | 4 | 257904 | 9679 | 70660857 |
Sudden death | 22.51 | 9.99 | 26 | 257882 | 21038 | 70649498 |
Walking aid user | 22.45 | 9.99 | 72 | 257836 | 7909 | 70662627 |
Feeling hot | 22.33 | 9.99 | 273 | 257635 | 48397 | 70622139 |
Intestinal ischaemia | 22.26 | 9.99 | 8 | 257900 | 12056 | 70658480 |
Specific gravity urine increased | 22.25 | 9.99 | 16 | 257892 | 430 | 70670106 |
Bladder cancer | 22.24 | 9.99 | 18 | 257890 | 17224 | 70653312 |
Confusional state | 22.16 | 9.99 | 1255 | 256653 | 283143 | 70387393 |
Monocyte percentage increased | 22.14 | 9.99 | 32 | 257876 | 2013 | 70668523 |
Infusion site pain | 22.09 | 9.99 | 92 | 257816 | 11472 | 70659064 |
Lung neoplasm malignant | 21.93 | 9.99 | 35 | 257873 | 24707 | 70645829 |
Lip pruritus | 21.90 | 9.99 | 20 | 257888 | 760 | 70669776 |
Penile haemorrhage | 21.88 | 9.99 | 17 | 257891 | 515 | 70670021 |
Nocturnal fear | 21.87 | 9.99 | 6 | 257902 | 10 | 70670526 |
Treatment noncompliance | 21.84 | 9.99 | 91 | 257817 | 46483 | 70624053 |
Metastases to lung | 21.52 | 9.99 | 17 | 257891 | 16467 | 70654069 |
Oesophageal carcinoma | 21.49 | 9.99 | 4 | 257904 | 9362 | 70661174 |
Rhinitis | 21.38 | 9.99 | 91 | 257817 | 11456 | 70659080 |
Toxic epidermal necrolysis | 21.34 | 9.99 | 73 | 257835 | 39484 | 70631052 |
Stress cardiomyopathy | 21.01 | 9.99 | 5 | 257903 | 9857 | 70660679 |
Blood calcium decreased | 20.98 | 9.99 | 46 | 257862 | 28800 | 70641736 |
Deep vein thrombosis | 20.94 | 9.99 | 281 | 257627 | 110761 | 70559775 |
Duodenal ulcer | 20.92 | 9.99 | 15 | 257893 | 15265 | 70655271 |
Flushing | 20.82 | 9.99 | 417 | 257491 | 81755 | 70588781 |
Blood alkaline phosphatase increased | 20.78 | 9.99 | 126 | 257782 | 58395 | 70612141 |
Lupus-like syndrome | 20.75 | 9.99 | 90 | 257818 | 11425 | 70659111 |
Polymenorrhoea | 20.36 | 9.99 | 21 | 257887 | 929 | 70669607 |
Gangrene | 20.29 | 9.99 | 3 | 257905 | 8306 | 70662230 |
Gait disturbance | 20.26 | 9.99 | 515 | 257393 | 184591 | 70485945 |
Blood urine present | 20.17 | 9.99 | 130 | 257778 | 19223 | 70651313 |
Haemophagocytic lymphohistiocytosis | 20.11 | 9.99 | 25 | 257883 | 19587 | 70650949 |
Bronchial disorder | 20.09 | 9.99 | 33 | 257875 | 2321 | 70668215 |
Intestinal obstruction | 20.04 | 9.99 | 73 | 257835 | 38752 | 70631784 |
Nitrite urine present | 20.04 | 9.99 | 23 | 257885 | 1149 | 70669387 |
Exostosis | 19.93 | 9.99 | 104 | 257804 | 14241 | 70656295 |
Hemiparesis | 19.88 | 9.99 | 54 | 257854 | 31415 | 70639121 |
Catatonia | 19.71 | 9.99 | 3 | 257905 | 8130 | 70662406 |
Therapy cessation | 19.66 | 9.99 | 60 | 257848 | 33616 | 70636920 |
Hypophagia | 19.63 | 9.99 | 81 | 257827 | 41489 | 70629047 |
Sneezing | 19.63 | 9.99 | 117 | 257791 | 16834 | 70653702 |
Nasal oedema | 19.62 | 9.99 | 24 | 257884 | 1283 | 70669253 |
Seronegative arthritis | 19.50 | 9.99 | 40 | 257868 | 3339 | 70667197 |
Epstein-Barr virus infection | 19.36 | 9.99 | 12 | 257896 | 13186 | 70657350 |
Pulmonary haemorrhage | 19.28 | 9.99 | 13 | 257895 | 13660 | 70656876 |
Renal disorder | 19.27 | 9.99 | 72 | 257836 | 37937 | 70632599 |
Bacterial test | 19.24 | 9.99 | 23 | 257885 | 1200 | 70669336 |
Osteonecrosis | 19.21 | 9.99 | 49 | 257859 | 29111 | 70641425 |
Cholestasis | 19.21 | 9.99 | 99 | 257809 | 47773 | 70622763 |
Demyelination | 19.20 | 9.99 | 64 | 257844 | 7172 | 70663364 |
Intestinal perforation | 19.18 | 9.99 | 18 | 257890 | 16026 | 70654510 |
Cholecystitis chronic | 19.02 | 9.99 | 76 | 257832 | 9300 | 70661236 |
Enterocolitis | 19 | 9.99 | 12 | 257896 | 13054 | 70657482 |
Myocardial ischaemia | 18.95 | 9.99 | 37 | 257871 | 24163 | 70646373 |
Activated partial thromboplastin time prolonged | 18.83 | 9.99 | 13 | 257895 | 13492 | 70657044 |
Swelling of eyelid | 18.82 | 9.99 | 37 | 257871 | 2995 | 70667541 |
Agitation | 18.82 | 9.99 | 233 | 257675 | 93142 | 70577394 |
Pain in extremity | 18.79 | 9.99 | 988 | 256920 | 327094 | 70343442 |
Hallucination, visual | 18.79 | 9.99 | 50 | 257858 | 29287 | 70641249 |
Hypothyroidism | 18.72 | 9.99 | 94 | 257814 | 45661 | 70624875 |
Schizophrenia | 18.68 | 9.99 | 20 | 257888 | 16748 | 70653788 |
Colorectal cancer | 18.64 | 9.99 | 4 | 257904 | 8466 | 70662070 |
Cardiac failure chronic | 18.62 | 9.99 | 7 | 257901 | 10262 | 70660274 |
Eosinophilic oesophagitis | 18.53 | 9.99 | 15 | 257893 | 483 | 70670053 |
Lichen nitidus | 18.52 | 9.99 | 8 | 257900 | 75 | 70670461 |
Tremor | 18.39 | 9.99 | 428 | 257480 | 155196 | 70515340 |
Enteritis | 18.36 | 9.99 | 12 | 257896 | 12819 | 70657717 |
Renal cancer | 18.33 | 9.99 | 10 | 257898 | 11786 | 70658750 |
Eosinophilic colitis | 18.22 | 9.99 | 14 | 257894 | 417 | 70670119 |
Blood glucose increased | 18.21 | 9.99 | 264 | 257644 | 102718 | 70567818 |
Skin burning sensation | 18.12 | 9.99 | 86 | 257822 | 11340 | 70659196 |
Tongue pruritus | 18.08 | 9.99 | 15 | 257893 | 500 | 70670036 |
Swollen tongue | 17.96 | 9.99 | 210 | 257698 | 36836 | 70633700 |
Joint dislocation | 17.93 | 9.99 | 102 | 257806 | 14429 | 70656107 |
Somnolence | 17.84 | 9.99 | 623 | 257285 | 214983 | 70455553 |
Blood pressure diastolic abnormal | 17.83 | 9.99 | 18 | 257890 | 15486 | 70655050 |
Drug level decreased | 17.81 | 9.99 | 12 | 257896 | 12612 | 70657924 |
Kidney transplant rejection | 17.72 | 9.99 | 7 | 257901 | 9954 | 70660582 |
Candida infection | 17.67 | 9.99 | 65 | 257843 | 34408 | 70636128 |
Faecaloma | 17.54 | 9.99 | 8 | 257900 | 10443 | 70660093 |
Pulse absent | 17.53 | 9.99 | 6 | 257902 | 9324 | 70661212 |
Oesophagitis | 17.42 | 9.99 | 35 | 257873 | 22617 | 70647919 |
Toxic encephalopathy | 17.41 | 9.99 | 8 | 257900 | 10398 | 70660138 |
Red blood cell sedimentation rate abnormal | 17.40 | 9.99 | 27 | 257881 | 19276 | 70651260 |
Splenomegaly | 17.39 | 9.99 | 26 | 257882 | 18844 | 70651692 |
Dry skin | 17.37 | 9.99 | 293 | 257615 | 55638 | 70614898 |
Acute respiratory failure | 17.29 | 9.99 | 119 | 257789 | 53546 | 70616990 |
Metabolic disorder | 17.28 | 9.99 | 4 | 257904 | 8036 | 70662500 |
Pancreatic carcinoma | 17.24 | 9.99 | 13 | 257895 | 12891 | 70657645 |
Premenstrual syndrome | 17.20 | 9.99 | 15 | 257893 | 536 | 70670000 |
Tubulointerstitial nephritis | 17.20 | 9.99 | 62 | 257846 | 33014 | 70637522 |
Urine ketone body present | 17.19 | 9.99 | 38 | 257870 | 3341 | 70667195 |
Migraine | 17.12 | 9.99 | 363 | 257545 | 71875 | 70598661 |
Upper respiratory fungal infection | 17.10 | 9.99 | 12 | 257896 | 310 | 70670226 |
Cardiac tamponade | 17.09 | 9.99 | 5 | 257903 | 8590 | 70661946 |
Accidental exposure to product | 17.08 | 9.99 | 49 | 257859 | 28002 | 70642534 |
Pulmonary toxicity | 17.01 | 9.99 | 9 | 257899 | 10789 | 70659747 |
Ehlers-Danlos syndrome | 17.01 | 9.99 | 9 | 257899 | 137 | 70670399 |
Red cell distribution width decreased | 16.92 | 9.99 | 25 | 257883 | 1604 | 70668932 |
Akathisia | 16.92 | 9.99 | 12 | 257896 | 12281 | 70658255 |
Ataxia | 16.90 | 9.99 | 37 | 257871 | 23180 | 70647356 |
Immunosuppressant drug level increased | 16.86 | 9.99 | 4 | 257904 | 7903 | 70662633 |
Cataract | 16.67 | 9.99 | 126 | 257782 | 55519 | 70615017 |
Crying | 16.64 | 9.99 | 133 | 257775 | 21066 | 70649470 |
Ventricular arrhythmia | 16.62 | 9.99 | 4 | 257904 | 7826 | 70662710 |
Magnesium deficiency | 16.60 | 9.99 | 15 | 257893 | 562 | 70669974 |
Urinary casts | 16.58 | 9.99 | 21 | 257887 | 1163 | 70669373 |
Tachycardia | 16.58 | 9.99 | 444 | 257464 | 158102 | 70512434 |
Dyshidrotic eczema | 16.54 | 9.99 | 15 | 257893 | 565 | 70669971 |
Bundle branch block right | 16.48 | 9.99 | 9 | 257899 | 10601 | 70659935 |
Acute graft versus host disease in skin | 16.48 | 9.99 | 3 | 257905 | 7134 | 70663402 |
Unintentional medical device removal | 16.44 | 9.99 | 3 | 257905 | 7121 | 70663415 |
Peripheral sensory neuropathy | 16.44 | 9.99 | 12 | 257896 | 12098 | 70658438 |
Adenovirus infection | 16.43 | 9.99 | 4 | 257904 | 7764 | 70662772 |
Gastric cancer | 16.42 | 9.99 | 6 | 257902 | 8949 | 70661587 |
Wrong technique in product usage process | 16.39 | 9.99 | 165 | 257743 | 68533 | 70602003 |
Hypertensive crisis | 16.37 | 9.99 | 28 | 257880 | 19234 | 70651302 |
Food intolerance | 16.31 | 9.99 | 36 | 257872 | 3162 | 70667374 |
Parkinsonism | 16.28 | 9.99 | 19 | 257889 | 15306 | 70655230 |
Arteriosclerosis | 16.25 | 9.99 | 22 | 257886 | 16616 | 70653920 |
Prothrombin time prolonged | 16.23 | 9.99 | 21 | 257887 | 16169 | 70654367 |
Pulmonary artery stenosis congenital | 16.23 | 9.99 | 5 | 257903 | 15 | 70670521 |
Prevertebral soft tissue swelling of cervical space | 16.18 | 9.99 | 6 | 257902 | 36 | 70670500 |
Bilirubin urine present | 16.17 | 9.99 | 12 | 257896 | 339 | 70670197 |
Hemiplegia | 16.13 | 9.99 | 16 | 257892 | 13879 | 70656657 |
Lung infiltration | 16.13 | 9.99 | 34 | 257874 | 21590 | 70648946 |
Febrile bone marrow aplasia | 16.12 | 9.99 | 12 | 257896 | 11979 | 70658557 |
Pulmonary congestion | 16.02 | 9.99 | 43 | 257865 | 25111 | 70645425 |
Pancreatitis | 16.01 | 9.99 | 148 | 257760 | 62520 | 70608016 |
Clostridium difficile colitis | 15.99 | 9.99 | 53 | 257855 | 28943 | 70641593 |
Cachexia | 15.97 | 9.99 | 8 | 257900 | 9892 | 70660644 |
Cells in urine | 15.89 | 9.99 | 10 | 257898 | 214 | 70670322 |
Sinus congestion | 15.89 | 9.99 | 113 | 257795 | 17260 | 70653276 |
Delirium | 15.87 | 9.99 | 184 | 257724 | 74430 | 70596106 |
Ileus paralytic | 15.84 | 9.99 | 6 | 257902 | 8755 | 70661781 |
Cytopenia | 15.83 | 9.99 | 24 | 257884 | 17299 | 70653237 |
Pulmonary alveolar haemorrhage | 15.81 | 9.99 | 9 | 257899 | 10360 | 70660176 |
Transient ischaemic attack | 15.75 | 9.99 | 100 | 257808 | 45844 | 70624692 |
Violence-related symptom | 15.73 | 9.99 | 16 | 257892 | 696 | 70669840 |
Thymus disorder | 15.71 | 9.99 | 11 | 257897 | 283 | 70670253 |
Colitis ischaemic | 15.60 | 9.99 | 17 | 257891 | 14120 | 70656416 |
Alanine aminotransferase abnormal | 15.46 | 9.99 | 5 | 257903 | 8054 | 70662482 |
Hepatic steatosis | 15.28 | 9.99 | 67 | 257841 | 33746 | 70636790 |
Diverticulitis | 15.27 | 9.99 | 89 | 257819 | 41645 | 70628891 |
Pneumonitis | 15.25 | 9.99 | 126 | 257782 | 54471 | 70616065 |
Endometrial ablation | 15.24 | 9.99 | 17 | 257891 | 823 | 70669713 |
Axillary pain | 15.22 | 9.99 | 26 | 257882 | 1889 | 70668647 |
Ankylosing spondylitis | 15.22 | 9.99 | 12 | 257896 | 11634 | 70658902 |
Granulocytopenia | 15.18 | 9.99 | 10 | 257898 | 10637 | 70659899 |
Acidosis | 15.11 | 9.99 | 27 | 257881 | 18236 | 70652300 |
Eosinophilic granulomatosis with polyangiitis | 15.09 | 9.99 | 35 | 257873 | 3178 | 70667358 |
Hepatitis | 15.05 | 9.99 | 113 | 257795 | 49867 | 70620669 |
Hydronephrosis | 15.04 | 9.99 | 20 | 257888 | 15222 | 70655314 |
Iron deficiency anaemia | 15.02 | 9.99 | 39 | 257869 | 23033 | 70647503 |
Myopathy | 14.97 | 9.99 | 28 | 257880 | 18584 | 70651952 |
Lower gastrointestinal haemorrhage | 14.85 | 9.99 | 19 | 257889 | 14701 | 70655835 |
Hypothermia | 14.85 | 9.99 | 33 | 257875 | 20561 | 70649975 |
Muscular weakness | 14.84 | 9.99 | 386 | 257522 | 137950 | 70532586 |
Patient elopement | 14.82 | 9.99 | 6 | 257902 | 47 | 70670489 |
Faeces discoloured | 14.78 | 9.99 | 49 | 257859 | 26760 | 70643776 |
Renal cyst | 14.78 | 9.99 | 16 | 257892 | 13329 | 70657207 |
Visual acuity reduced | 14.76 | 9.99 | 52 | 257856 | 27878 | 70642658 |
Spinal compression fracture | 14.75 | 9.99 | 21 | 257887 | 15532 | 70655004 |
Atopy | 14.75 | 9.99 | 11 | 257897 | 313 | 70670223 |
Blood albumin decreased | 14.72 | 9.99 | 37 | 257871 | 22090 | 70648446 |
Hyperuricaemia | 14.71 | 9.99 | 11 | 257897 | 10955 | 70659581 |
Suicide attempt | 14.70 | 9.99 | 202 | 257706 | 79308 | 70591228 |
Deafness | 14.69 | 9.99 | 30 | 257878 | 19273 | 70651263 |
Pneumonia fungal | 14.67 | 9.99 | 9 | 257899 | 9944 | 70660592 |
Joint range of motion decreased | 14.67 | 9.99 | 152 | 257756 | 25874 | 70644662 |
Skin toxicity | 14.66 | 9.99 | 4 | 257904 | 7194 | 70663342 |
Anal abscess | 14.66 | 9.99 | 6 | 257902 | 8352 | 70662184 |
Protrusion tongue | 14.65 | 9.99 | 12 | 257896 | 393 | 70670143 |
White blood cell count increased | 14.63 | 9.99 | 172 | 257736 | 69401 | 70601135 |
Reaction to excipient | 14.61 | 9.99 | 22 | 257886 | 1436 | 70669100 |
Enterococcal infection | 14.53 | 9.99 | 19 | 257889 | 14563 | 70655973 |
Pulmonary function test decreased | 14.50 | 9.99 | 56 | 257852 | 6745 | 70663791 |
Hypernatraemia | 14.46 | 9.99 | 15 | 257893 | 12746 | 70657790 |
Hepatic cytolysis | 14.46 | 9.99 | 30 | 257878 | 19162 | 70651374 |
Electrocardiogram QT prolonged | 14.45 | 9.99 | 215 | 257693 | 83302 | 70587234 |
Pneumothorax | 14.42 | 9.99 | 47 | 257861 | 25799 | 70644737 |
Cardiovascular disorder | 14.38 | 9.99 | 24 | 257884 | 16646 | 70653890 |
Poor feeding infant | 14.34 | 9.99 | 8 | 257900 | 136 | 70670400 |
Poisoning deliberate | 14.32 | 9.99 | 25 | 257883 | 17035 | 70653501 |
Pancreatitis acute | 14.22 | 9.99 | 101 | 257807 | 45123 | 70625413 |
Lactose intolerance | 14.21 | 9.99 | 27 | 257881 | 2131 | 70668405 |
Diarrhoea haemorrhagic | 14.21 | 9.99 | 13 | 257895 | 11717 | 70658819 |
Chronic obstructive pulmonary disease | 14.09 | 9.99 | 198 | 257710 | 77443 | 70593093 |
Tachyarrhythmia | 14.07 | 9.99 | 3 | 257905 | 6379 | 70664157 |
Neutropenic sepsis | 13.96 | 9.99 | 45 | 257863 | 24785 | 70645751 |
Venoocclusive liver disease | 13.96 | 9.99 | 11 | 257897 | 10667 | 70659869 |
Anaphylactoid reaction | 13.93 | 9.99 | 45 | 257863 | 4962 | 70665574 |
Torsade de pointes | 13.92 | 9.99 | 28 | 257880 | 18088 | 70652448 |
Escherichia sepsis | 13.92 | 9.99 | 5 | 257903 | 7538 | 70662998 |
Hyperplastic cholecystopathy | 13.88 | 9.99 | 8 | 257900 | 145 | 70670391 |
Acute pulmonary oedema | 13.86 | 9.99 | 17 | 257891 | 13395 | 70657141 |
Red blood cell count decreased | 13.84 | 9.99 | 122 | 257786 | 52039 | 70618497 |
Hypomagnesaemia | 13.83 | 9.99 | 89 | 257819 | 40675 | 70629861 |
Acute coronary syndrome | 13.81 | 9.99 | 33 | 257875 | 20046 | 70650490 |
Fixed eruption | 13.77 | 9.99 | 29 | 257879 | 2467 | 70668069 |
Pharyngeal oedema | 13.73 | 9.99 | 101 | 257807 | 15595 | 70654941 |
Condition aggravated | 13.67 | 9.99 | 1765 | 256143 | 425870 | 70244666 |
Endophthalmitis | 13.67 | 9.99 | 3 | 257905 | 6252 | 70664284 |
Urine bilirubin decreased | 13.64 | 9.99 | 8 | 257900 | 150 | 70670386 |
Abdominal pain | 13.61 | 9.99 | 1065 | 256843 | 341062 | 70329474 |
Angina unstable | 13.60 | 9.99 | 23 | 257885 | 15870 | 70654666 |
Schizophreniform disorder | 13.60 | 9.99 | 8 | 257900 | 151 | 70670385 |
Glomerular filtration rate decreased | 13.58 | 9.99 | 35 | 257873 | 20721 | 70649815 |
Bacterial infection | 13.55 | 9.99 | 50 | 257858 | 26442 | 70644094 |
Injection | 13.51 | 9.99 | 4 | 257904 | 10 | 70670526 |
Right ventricular failure | 13.50 | 9.99 | 39 | 257869 | 22235 | 70648301 |
Malnutrition | 13.49 | 9.99 | 34 | 257874 | 20283 | 70650253 |
Brain oedema | 13.47 | 9.99 | 42 | 257866 | 23376 | 70647160 |
Diabetes mellitus inadequate control | 13.47 | 9.99 | 40 | 257868 | 22605 | 70647931 |
Sensitivity to weather change | 13.43 | 9.99 | 58 | 257850 | 7347 | 70663189 |
Product monitoring error | 13.37 | 9.99 | 4 | 257904 | 6772 | 70663764 |
Troponin increased | 13.36 | 9.99 | 25 | 257883 | 16589 | 70653947 |
Benign prostatic hyperplasia | 13.35 | 9.99 | 11 | 257897 | 10432 | 70660104 |
Large intestine perforation | 13.34 | 9.99 | 17 | 257891 | 13178 | 70657358 |
Mitral valve incompetence | 13.31 | 9.99 | 51 | 257857 | 26677 | 70643859 |
Product use in unapproved indication | 13.26 | 9.99 | 900 | 257008 | 206578 | 70463958 |
Hepatic lesion | 13.23 | 9.99 | 3 | 257905 | 6114 | 70664422 |
Device related infection | 13.23 | 9.99 | 66 | 257842 | 32119 | 70638417 |
Tenosynovitis | 13.13 | 9.99 | 19 | 257889 | 13957 | 70656579 |
Paternal exposure timing unspecified | 13.05 | 9.99 | 6 | 257902 | 66 | 70670470 |
Depressed mood | 13.04 | 9.99 | 228 | 257680 | 43592 | 70626944 |
Venous thrombosis | 12.98 | 9.99 | 4 | 257904 | 6645 | 70663891 |
Vertigo CNS origin | 12.96 | 9.99 | 5 | 257903 | 34 | 70670502 |
Lethargy | 12.92 | 9.99 | 194 | 257714 | 75056 | 70595480 |
Colon cancer | 12.90 | 9.99 | 20 | 257888 | 14286 | 70656250 |
Euglycaemic diabetic ketoacidosis | 12.89 | 9.99 | 3 | 257905 | 6004 | 70664532 |
Loss of personal independence in daily activities | 12.89 | 9.99 | 224 | 257684 | 84686 | 70585850 |
Pharyngeal swelling | 12.85 | 9.99 | 52 | 257856 | 6401 | 70664135 |
Cardiac disorder | 12.84 | 9.99 | 146 | 257762 | 59269 | 70611267 |
Myocarditis | 12.83 | 9.99 | 31 | 257877 | 18762 | 70651774 |
Systemic inflammatory response syndrome | 12.82 | 9.99 | 12 | 257896 | 10700 | 70659836 |
Cystitis | 12.81 | 9.99 | 109 | 257799 | 46832 | 70623704 |
Anxiety | 12.75 | 9.99 | 948 | 256960 | 219382 | 70451154 |
Drug level below therapeutic | 12.70 | 9.99 | 8 | 257900 | 8715 | 70661821 |
Blood pressure systolic abnormal | 12.68 | 9.99 | 17 | 257891 | 12892 | 70657644 |
Rhinitis allergic | 12.65 | 9.99 | 67 | 257841 | 9228 | 70661308 |
Breast cancer stage III | 12.64 | 9.99 | 53 | 257855 | 6628 | 70663908 |
Injection site urticaria | 12.64 | 9.99 | 79 | 257829 | 11559 | 70658977 |
Myositis | 12.63 | 9.99 | 28 | 257880 | 17461 | 70653075 |
Coronary artery bypass | 12.62 | 9.99 | 3 | 257905 | 5917 | 70664619 |
Pulmonary arterial hypertension | 12.60 | 9.99 | 69 | 257839 | 32786 | 70637750 |
Blood pressure systolic decreased | 12.59 | 9.99 | 10 | 257898 | 9661 | 70660875 |
Pneumonia bacterial | 12.55 | 9.99 | 26 | 257882 | 16615 | 70653921 |
Coronary arterial stent insertion | 12.51 | 9.99 | 3 | 257905 | 5884 | 70664652 |
C-reactive protein | 12.49 | 9.99 | 25 | 257883 | 2051 | 70668485 |
Gastritis erosive | 12.45 | 9.99 | 11 | 257897 | 10084 | 70660452 |
Spinal fracture | 12.41 | 9.99 | 25 | 257883 | 16142 | 70654394 |
Dermatitis contact | 12.41 | 9.99 | 69 | 257839 | 9680 | 70660856 |
Urine output decreased | 12.39 | 9.99 | 27 | 257881 | 16943 | 70653593 |
Cytokine release syndrome | 12.37 | 9.99 | 149 | 257759 | 26318 | 70644218 |
Tooth disorder | 12.36 | 9.99 | 45 | 257863 | 23893 | 70646643 |
Urine amphetamine positive | 12.31 | 9.99 | 6 | 257902 | 76 | 70670460 |
Femoral neck fracture | 12.30 | 9.99 | 9 | 257899 | 9064 | 70661472 |
Gastroenteritis | 12.27 | 9.99 | 65 | 257843 | 31148 | 70639388 |
Biliary dyskinesia | 12.23 | 9.99 | 27 | 257881 | 2372 | 70668164 |
Congestive cardiomyopathy | 12.21 | 9.99 | 13 | 257895 | 10913 | 70659623 |
Eye infection bacterial | 12.20 | 9.99 | 9 | 257899 | 252 | 70670284 |
Hypertriglyceridaemia | 12.17 | 9.99 | 15 | 257893 | 11796 | 70658740 |
Premature labour | 12.12 | 9.99 | 7 | 257901 | 7993 | 70662543 |
Cerebral ischaemia | 12.07 | 9.99 | 12 | 257896 | 10400 | 70660136 |
Sinus headache | 12.05 | 9.99 | 40 | 257868 | 4473 | 70666063 |
Oligoarthritis | 11.97 | 9.99 | 12 | 257896 | 513 | 70670023 |
Apnoea | 11.92 | 9.99 | 13 | 257895 | 10796 | 70659740 |
Specific gravity urine decreased | 11.91 | 9.99 | 15 | 257893 | 826 | 70669710 |
Staphylococcal sepsis | 11.89 | 9.99 | 19 | 257889 | 13408 | 70657128 |
Photosensitivity reaction | 11.89 | 9.99 | 115 | 257793 | 19225 | 70651311 |
Atrioventricular block first degree | 11.84 | 9.99 | 15 | 257893 | 11658 | 70658878 |
Marginal zone lymphoma | 11.84 | 9.99 | 6 | 257902 | 83 | 70670453 |
Pulmonary thrombosis | 11.80 | 9.99 | 14 | 257894 | 11194 | 70659342 |
Coronavirus infection | 11.78 | 9.99 | 4 | 257904 | 6248 | 70664288 |
Obesity | 11.78 | 9.99 | 149 | 257759 | 26622 | 70643914 |
Nystagmus | 11.78 | 9.99 | 10 | 257898 | 9345 | 70661191 |
Mixed liver injury | 11.78 | 9.99 | 4 | 257904 | 6245 | 70664291 |
Humerus fracture | 11.77 | 9.99 | 8 | 257900 | 8370 | 70662166 |
Autoimmune arthritis | 11.77 | 9.99 | 7 | 257901 | 135 | 70670401 |
Electrocardiogram QRS complex prolonged | 11.72 | 9.99 | 11 | 257897 | 9795 | 70660741 |
Blood lactic acid increased | 11.71 | 9.99 | 14 | 257894 | 11159 | 70659377 |
Hepatocellular injury | 11.71 | 9.99 | 109 | 257799 | 45982 | 70624554 |
Tricuspid valve incompetence | 11.69 | 9.99 | 30 | 257878 | 17787 | 70652749 |
Pain in jaw | 11.68 | 9.99 | 99 | 257809 | 42570 | 70627966 |
Oxygen saturation decreased | 11.67 | 9.99 | 328 | 257580 | 116101 | 70554435 |
Multiple fractures | 11.63 | 9.99 | 5 | 257903 | 6760 | 70663776 |
Rib fracture | 11.61 | 9.99 | 50 | 257858 | 25306 | 70645230 |
Rash macular | 11.59 | 9.99 | 143 | 257765 | 25401 | 70645135 |
Embolic stroke | 11.59 | 9.99 | 6 | 257902 | 7283 | 70663253 |
Supraventricular tachycardia | 11.59 | 9.99 | 35 | 257873 | 19675 | 70650861 |
Red blood cell count increased | 11.59 | 9.99 | 36 | 257872 | 3888 | 70666648 |
Hyperthyroidism | 11.58 | 9.99 | 36 | 257872 | 20055 | 70650481 |
Illness | 11.56 | 9.99 | 171 | 257737 | 31620 | 70638916 |
Autophobia | 11.55 | 9.99 | 4 | 257904 | 19 | 70670517 |
Ketoacidosis | 11.54 | 9.99 | 6 | 257902 | 7263 | 70663273 |
Nail operation | 11.48 | 9.99 | 12 | 257896 | 539 | 70669997 |
Drug ineffective | 11.48 | 9.99 | 3699 | 254209 | 936053 | 69734483 |
Therapeutic product effect incomplete | 11.44 | 9.99 | 340 | 257568 | 119542 | 70550994 |
Arterial occlusive disease | 11.41 | 9.99 | 7 | 257901 | 7735 | 70662801 |
Crepitations | 11.36 | 9.99 | 9 | 257899 | 8705 | 70661831 |
Head injury | 11.35 | 9.99 | 75 | 257833 | 34066 | 70636470 |
Peritonitis bacterial | 11.34 | 9.99 | 10 | 257898 | 9174 | 70661362 |
Cytomegalovirus test positive | 11.33 | 9.99 | 3 | 257905 | 5505 | 70665031 |
Retinal haemorrhage | 11.32 | 9.99 | 7 | 257901 | 7703 | 70662833 |
Partial seizures | 11.31 | 9.99 | 8 | 257900 | 8197 | 70662339 |
Hypotonia | 11.27 | 9.99 | 16 | 257892 | 11849 | 70658687 |
Dysarthria | 11.27 | 9.99 | 159 | 257749 | 62154 | 70608382 |
Hypoalbuminaemia | 11.21 | 9.99 | 34 | 257874 | 19088 | 70651448 |
Blood uric acid increased | 11.20 | 9.99 | 10 | 257898 | 9119 | 70661417 |
Radiation inflammation | 11.18 | 9.99 | 12 | 257896 | 556 | 70669980 |
Motor dysfunction | 11.11 | 9.99 | 19 | 257889 | 13051 | 70657485 |
Hepatitis fulminant | 11.10 | 9.99 | 5 | 257903 | 6576 | 70663960 |
Malignant melanoma | 11.10 | 9.99 | 21 | 257887 | 13879 | 70656657 |
Blepharospasm | 11.10 | 9.99 | 35 | 257873 | 3810 | 70666726 |
Intestinal haemorrhage | 11.09 | 9.99 | 4 | 257904 | 6016 | 70664520 |
Generalised oedema | 11.08 | 9.99 | 41 | 257867 | 21667 | 70648869 |
Hepatitis B | 11.06 | 9.99 | 8 | 257900 | 8106 | 70662430 |
Sinus tachycardia | 11.03 | 9.99 | 75 | 257833 | 33838 | 70636698 |
Fistula | 11.02 | 9.99 | 14 | 257894 | 10867 | 70659669 |
Adenoidal hypertrophy | 11.00 | 9.99 | 7 | 257901 | 153 | 70670383 |
Chest pain | 10.97 | 9.99 | 776 | 257132 | 250484 | 70420052 |
Decompression sickness | 10.96 | 9.99 | 5 | 257903 | 54 | 70670482 |
Tendon disorder | 10.90 | 9.99 | 50 | 257858 | 6501 | 70664035 |
Squamous cell carcinoma | 10.86 | 9.99 | 23 | 257885 | 14581 | 70655955 |
Portal hypertension | 10.85 | 9.99 | 5 | 257903 | 6487 | 70664049 |
Culture urine positive | 10.82 | 9.99 | 37 | 257871 | 4200 | 70666336 |
Bruxism | 10.82 | 9.99 | 34 | 257874 | 3695 | 70666841 |
Laryngeal stenosis | 10.80 | 9.99 | 15 | 257893 | 909 | 70669627 |
Rhinorrhoea | 10.80 | 9.99 | 317 | 257591 | 66054 | 70604482 |
Epidermolysis bullosa | 10.69 | 9.99 | 8 | 257900 | 229 | 70670307 |
Ear swelling | 10.66 | 9.99 | 19 | 257889 | 1428 | 70669108 |
Idiopathic angioedema | 10.65 | 9.99 | 4 | 257904 | 25 | 70670511 |
Drug abuser | 10.63 | 9.99 | 4 | 257904 | 5860 | 70664676 |
Heart rate decreased | 10.60 | 9.99 | 160 | 257748 | 61855 | 70608681 |
Post viral fatigue syndrome | 10.60 | 9.99 | 9 | 257899 | 310 | 70670226 |
Product lot number issue | 10.57 | 9.99 | 7 | 257901 | 164 | 70670372 |
Blood culture positive | 10.57 | 9.99 | 8 | 257900 | 7918 | 70662618 |
Cholangitis | 10.56 | 9.99 | 16 | 257892 | 11533 | 70659003 |
Hypogammaglobulinaemia | 10.53 | 9.99 | 16 | 257892 | 11522 | 70659014 |
Tarsal tunnel syndrome | 10.53 | 9.99 | 11 | 257897 | 494 | 70670042 |
Blood pressure diastolic decreased | 10.52 | 9.99 | 53 | 257855 | 25727 | 70644809 |
Haemoglobin abnormal | 10.52 | 9.99 | 5 | 257903 | 6372 | 70664164 |
Post-tussive vomiting | 10.52 | 9.99 | 4 | 257904 | 26 | 70670510 |
Haemoptysis | 10.51 | 9.99 | 128 | 257780 | 51324 | 70619212 |
Pregnancy with injectable contraceptive | 10.50 | 9.99 | 6 | 257902 | 107 | 70670429 |
Nephrotic syndrome | 10.46 | 9.99 | 14 | 257894 | 10626 | 70659910 |
Full blood count decreased | 10.44 | 9.99 | 48 | 257860 | 23870 | 70646666 |
Breast cancer metastatic | 10.33 | 9.99 | 13 | 257895 | 10133 | 70660403 |
Drug withdrawal syndrome | 10.32 | 9.99 | 73 | 257835 | 32642 | 70637894 |
Lung consolidation | 10.31 | 9.99 | 9 | 257899 | 8297 | 70662239 |
Spinal fusion surgery | 10.30 | 9.99 | 35 | 257873 | 3962 | 70666574 |
Malaise | 10.29 | 9.99 | 1757 | 256151 | 431175 | 70239361 |
Urticaria pressure | 10.27 | 9.99 | 4 | 257904 | 28 | 70670508 |
Tendinous contracture | 10.26 | 9.99 | 6 | 257902 | 112 | 70670424 |
Sopor | 10.24 | 9.99 | 69 | 257839 | 31198 | 70639338 |
Tonsillar hypertrophy | 10.21 | 9.99 | 18 | 257890 | 1341 | 70669195 |
Hepatitis cholestatic | 10.20 | 9.99 | 19 | 257889 | 12631 | 70657905 |
Left ventricular failure | 10.19 | 9.99 | 10 | 257898 | 8718 | 70661818 |
Nasal pruritus | 10.18 | 9.99 | 10 | 257898 | 417 | 70670119 |
Lymphoma | 10.17 | 9.99 | 26 | 257882 | 15436 | 70655100 |
Periorbital swelling | 10.15 | 9.99 | 24 | 257884 | 2206 | 70668330 |
Blood phosphorus increased | 10.15 | 9.99 | 6 | 257902 | 6764 | 70663772 |
Uterine pain | 10.14 | 9.99 | 7 | 257901 | 176 | 70670360 |
Therapy interrupted | 10.12 | 9.99 | 51 | 257857 | 24751 | 70645785 |
Organising pneumonia | 10.11 | 9.99 | 13 | 257895 | 10037 | 70660499 |
Eosinophil count increased | 10.10 | 9.99 | 92 | 257816 | 15130 | 70655406 |
Gastrointestinal perforation | 10.09 | 9.99 | 4 | 257904 | 5677 | 70664859 |
Polyuria | 10.06 | 9.99 | 21 | 257887 | 13385 | 70657151 |
Heart rate irregular | 10.06 | 9.99 | 65 | 257843 | 29678 | 70640858 |
Embolism | 10.04 | 9.99 | 20 | 257888 | 12968 | 70657568 |
Microcytosis | 10.03 | 9.99 | 9 | 257899 | 334 | 70670202 |
Gastrointestinal inflammation | 10.02 | 9.99 | 6 | 257902 | 6717 | 70663819 |
None
Source | Code | Description |
---|---|---|
ATC | R06AE07 | RESPIRATORY SYSTEM ANTIHISTAMINES FOR SYSTEMIC USE ANTIHISTAMINES FOR SYSTEMIC USE Piperazine derivatives |
ATC | S01GX12 | SENSORY ORGANS OPHTHALMOLOGICALS DECONGESTANTS AND ANTIALLERGICS Other antiallergics |
FDA MoA | N0000000190 | Histamine H1 Receptor Antagonists |
FDA EPC | N0000175587 | Histamine-1 Receptor Antagonist |
CHEBI has role | CHEBI:35703 | Xenobiotic |
CHEBI has role | CHEBI:37955 | H1 receptor antagonists |
CHEBI has role | CHEBI:50857 | anti-allergic drugs |
CHEBI has role | CHEBI:78298 | environmental contaminants |
MeSH PA | D018926 | Anti-Allergic Agents |
MeSH PA | D018494 | Histamine Agents |
MeSH PA | D006633 | Histamine Antagonists |
MeSH PA | D006634 | Histamine H1 Antagonists |
MeSH PA | D039563 | Histamine H1 Antagonists, Non-Sedating |
MeSH PA | D018377 | Neurotransmitter Agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Vasomotor rhinitis | indication | 8229003 | DOID:4730 |
Allergic rhinitis | indication | 61582004 | |
Nasal discharge | indication | 64531003 | |
Nasal congestion | indication | 68235000 | |
Sneezing | indication | 76067001 | |
Common cold | indication | 82272006 | DOID:10459 |
Chronic idiopathic urticaria | indication | 302162004 | |
Seasonal allergic rhinitis | indication | 367498001 | |
Allergic conjunctivitis | indication | 473460002 | DOID:11204 |
Atopic dermatitis | off-label use | 24079001 | DOID:3310 |
Urticaria | off-label use | 126485001 | |
Glaucoma | contraindication | 23986001 | DOID:1686 |
Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Coronary arteriosclerosis | contraindication | 53741008 | DOID:3393 |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Chronic renal failure syndrome | contraindication | 90688005 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Disease of liver | contraindication | 235856003 | DOID:409 |
Benign prostatic hyperplasia | contraindication | 266569009 | |
Retention of urine | contraindication | 267064002 | |
Drowsy | contraindication | 271782001 | |
Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
Hypertensive urgency | contraindication | 443482000 | |
Hemodialysis with High-Flux Membrane | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 3.03 | acidic |
pKa2 | 8.21 | Basic |
pKa3 | 3.72 | Basic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
5MG;120MG | ZYRTEC-D 12 HOUR | J AND J CONSUMER INC | N021150 | Nov. 9, 2007 | OTC | TABLET, EXTENDED RELEASE | ORAL | 7226614 | June 10, 2022 | TREATMENT OF SEASONAL AND PERENNIAL ALLERGIC RHINITIS SYMPTOMS |
10MG/ML (10MG/ML) | QUZYTTIR | JDP | N211415 | Oct. 4, 2019 | RX | SOLUTION | INTRAVENOUS | 8513259 | Feb. 11, 2030 | METHOD OF INCREASING PEAK PLASMA OR ONSET OF PLASMA CONCENTRATION BY INTRAVENOUS INJECTION IN INDIVIDUALS IN NEED OF TREATMENT FOR ACUTE URTICARIA |
10MG/ML (10MG/ML) | QUZYTTIR | JDP | N211415 | Oct. 4, 2019 | RX | SOLUTION | INTRAVENOUS | 9119771 | Feb. 11, 2030 | TREATMENT OF ACUTE URTICARIA |
10MG/ML (10MG/ML) | QUZYTTIR | JDP | N211415 | Oct. 4, 2019 | RX | SOLUTION | INTRAVENOUS | 9180090 | Feb. 11, 2030 | TREATMENT OF ACUTE URTICARIA |
10MG/ML (10MG/ML) | QUZYTTIR | JDP | N211415 | Oct. 4, 2019 | RX | SOLUTION | INTRAVENOUS | 8263581 | Feb. 28, 2030 | TREATMENT OF ACUTE URTICARIA |
10MG/ML (10MG/ML) | QUZYTTIR | JDP | N211415 | Oct. 4, 2019 | RX | SOLUTION | INTRAVENOUS | 8314083 | Feb. 28, 2030 | METHOD OF TREATMENT IN PATIENTS WITH CONCOMITANT ANGIOEDEMA |
EQ 0.24% BASE | ZERVIATE | EYEVANCE | N208694 | May 30, 2017 | RX | SOLUTION/DROPS | OPHTHALMIC | 8829005 | March 15, 2030 | TREATMENT OF OCULAR ITCHING ASSOCIATED WITH ALLERGIC CONJUNCTIVITIS |
EQ 0.24% BASE | ZERVIATE | EYEVANCE | N208694 | May 30, 2017 | RX | SOLUTION/DROPS | OPHTHALMIC | 9993471 | March 15, 2030 | TREATMENT OF OCULAR ITCHING ASSOCIATED WITH ALLERGIC CONJUNCTIVITIS |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
---|---|---|---|---|---|---|---|---|---|
10MG/ML (10MG/ML) | QUZYTTIR | JDP | N211415 | Oct. 4, 2019 | RX | SOLUTION | INTRAVENOUS | Oct. 4, 2022 | NEW PRODUCT |
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Histamine H1 receptor | GPCR | ANTAGONIST | Ki | 7.91 | WOMBAT-PK | CHEMBL | |||
Potassium voltage-gated channel subfamily H member 2 | Ion channel | IC50 | 4.52 | CHEMBL | |||||
Angiopoietin-1 receptor | Kinase | Kd | 4.05 | CHEMBL |
ID | Source |
---|---|
4024005 | VUID |
N0000022010 | NUI |
D00664 | KEGG_DRUG |
83881-52-1 | SECONDARY_CAS_RN |
203150 | RXNORM |
4020943 | VANDF |
4024005 | VANDF |
C0055147 | UMLSCUI |
CHEBI:3561 | CHEBI |
CHEMBL1000 | ChEMBL_ID |
CHEMBL1607273 | ChEMBL_ID |
DB00341 | DRUGBANK_ID |
CHEMBL1201113 | ChEMBL_ID |
D017332 | MESH_DESCRIPTOR_UI |
2678 | PUBCHEM_CID |
1222 | IUPHAR_LIGAND_ID |
5520 | INN_ID |
YO7261ME24 | UNII |
130140 | MMSL |
38293 | MMSL |
4399 | MMSL |
4400 | MMSL |
d03827 | MMSL |
003803 | NDDF |
003804 | NDDF |
108655000 | SNOMEDCT_US |
108656004 | SNOMEDCT_US |
372523007 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
good sense all day allergy d | HUMAN OTC DRUG LABEL | 2 | 0113-0147 | TABLET, FILM COATED, EXTENDED RELEASE | 5 mg | ORAL | ANDA | 16 sections |
Good Sense All Day Allergy D | HUMAN OTC DRUG LABEL | 2 | 0113-0176 | TABLET, EXTENDED RELEASE | 5 mg | ORAL | ANDA | 16 sections |
Good Sense Childrens All Day Allergy | HUMAN OTC DRUG LABEL | 1 | 0113-0189 | SOLUTION | 5 mg | ORAL | ANDA | 16 sections |
Good Sense Childrens All Day Allergy | HUMAN OTC DRUG LABEL | 1 | 0113-0503 | SOLUTION | 5 mg | ORAL | ANDA | 16 sections |
Good Sense All Day Allergy | HUMAN OTC DRUG LABEL | 1 | 0113-0981 | CAPSULE, LIQUID FILLED | 10 mg | ORAL | ANDA | 16 sections |
good sense all day allergy | HUMAN OTC DRUG LABEL | 1 | 0113-1036 | CAPSULE, LIQUID FILLED | 10 mg | ORAL | ANDA | 16 sections |
All Day Allergy-D | HUMAN OTC DRUG LABEL | 2 | 0113-2176 | TABLET, EXTENDED RELEASE | 5 mg | ORAL | ANDA | 16 sections |
Basic Care All Day Allergy | HUMAN OTC DRUG LABEL | 1 | 0113-7002 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 16 sections |
BASIC CARE ALL DAY ALLERGY | HUMAN OTC DRUG LABEL | 1 | 0113-7036 | CAPSULE, LIQUID FILLED | 10 mg | ORAL | ANDA | 16 sections |
basic care childrens all day allergy | HUMAN OTC DRUG LABEL | 1 | 0113-7189 | SOLUTION | 5 mg | ORAL | ANDA | 16 sections |
basic care childrens all day allergy | HUMAN OTC DRUG LABEL | 1 | 0113-7475 | SOLUTION | 5 mg | ORAL | ANDA | 16 sections |
Good Sense all day allergy | HUMAN OTC DRUG LABEL | 1 | 0113-9458 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 16 sections |
Cetirizine Hydrochloride | HUMAN OTC DRUG LABEL | 1 | 0121-4780 | SYRUP | 5 mg | ORAL | ANDA | 17 sections |
Cetirizine Hydrochloride (Allergy) | Human OTC Drug Label | 1 | 0363-0068 | CAPSULE | 10 mg | ORAL | ANDA | 16 sections |
Cetirizine Hydrochloride | Human OTC Drug Label | 1 | 0363-0471 | TABLET, ORALLY DISINTEGRATING | 10 mg | ORAL | ANDA | 14 sections |
Wal Zyr | HUMAN OTC DRUG LABEL | 1 | 0363-0495 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 16 sections |
Wal-Zyr | HUMAN OTC DRUG LABEL | 1 | 0363-0606 | TABLET | 10 mg | ORAL | ANDA | 17 sections |
Wal-Zyr | HUMAN OTC DRUG LABEL | 1 | 0363-0606 | TABLET | 10 mg | ORAL | ANDA | 17 sections |
Wal-Zyr | HUMAN OTC DRUG LABEL | 1 | 0363-0741 | CAPSULE | 10 mg | ORAL | ANDA | 16 sections |
Wal-Zyr | HUMAN OTC DRUG LABEL | 1 | 0363-0921 | CAPSULE | 10 mg | ORAL | NDA | 17 sections |
Childrens Dye Free Wal Zyr | HUMAN OTC DRUG LABEL | 1 | 0363-0953 | SOLUTION | 5 mg | ORAL | ANDA | 16 sections |
Wal-Zyr D | HUMAN OTC DRUG LABEL | 2 | 0363-0989 | TABLET, FILM COATED, EXTENDED RELEASE | 5 mg | ORAL | ANDA | 17 sections |
Wal-Zyr D | HUMAN OTC DRUG LABEL | 2 | 0363-0989 | TABLET, FILM COATED, EXTENDED RELEASE | 5 mg | ORAL | ANDA | 17 sections |
Cetirizine | HUMAN OTC DRUG LABEL | 1 | 0363-1040 | CAPSULE, LIQUID FILLED | 10 mg | ORAL | ANDA | 16 sections |
WAL ZYR D | HUMAN OTC DRUG LABEL | 2 | 0363-1147 | TABLET, FILM COATED, EXTENDED RELEASE | 5 mg | ORAL | ANDA | 16 sections |
24 HOUR ALLERGY | HUMAN OTC DRUG LABEL | 1 | 0363-1219 | CAPSULE | 10 mg | ORAL | NDA | 17 sections |
childrens dye free wal zyr | HUMAN OTC DRUG LABEL | 1 | 0363-1475 | SOLUTION | 5 mg | ORAL | ANDA | 16 sections |
Wal-Zyr Cetirizine Hydrochloride | HUMAN OTC DRUG LABEL | 1 | 0363-2088 | SOLUTION | 5 mg | ORAL | ANDA | 17 sections |
Wal-Zyr Cetirizine Hydrochloride | HUMAN OTC DRUG LABEL | 1 | 0363-2102 | SOLUTION | 5 mg | ORAL | ANDA | 17 sections |
Wal-Zyr All Day Allergy | HUMAN OTC DRUG LABEL | 1 | 0363-2106 | SOLUTION | 5 mg | ORAL | ANDA | 17 sections |