cefaloglycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
antibiotics, cefalosporanic acid derivatives	572	3577-01-3

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

cephaloglycin
cefaloglycin
cefaloglycine
cephaloglycine
kefglycin
kafocin

A cephalorsporin antibiotic.

Molecular weight: 405.43
Formula: C18H19N3O6S
CLOGP: -2.56
LIPINSKI: 0
HAC: 9
HDO: 3
TPSA: 139.03
ALOGS: -3.44
ROTB: 7

Status: OFM

Legend:
OFP - off patent
OFM - off market
ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
June 12, 1970	FDA	LILLY

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D000900	Anti-Bacterial Agents
MeSH PA	D000890	Anti-Infective Agents
CHEBI has role	CHEBI:33281	antibiotics

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	2.39	acidic
pKa2	13.53	acidic
pKa3	7.67	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Bacterial penicillin-binding protein	Enzyme		PBPA_ECOLI PBPB_ECOLI DACC_ECOLI PBP2_ECOLI FTSI_ECOLI DACA_ECOLI DACB_ECOLI	INHIBITOR				CHEMBL	CHEMBL

External reference:

ID	Source
D01949	KEGG_DRUG
22202-75-1	SECONDARY_CAS_RN
CHEBI:34613	CHEBI
CHEMBL1200971	ChEMBL_ID
12193	IUPHAR_LIGAND_ID
DB00689	DRUGBANK_ID
002714	NDDF
39123009	SNOMEDCT_US
C0007721	UMLSCUI
D002507	MESH_DESCRIPTOR_UI
19150	PUBCHEM_CID
NE7R11LA95	UNII

Pharmaceutical products:

None