linzagolix 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
gonadotropin releasing hormone (GnRH) antagonists 5701 935283-04-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • linzagolix
  • linzagolix choline
  • yselty
  • OBE2109
  • KLH-2109
Linzagolix is a selective, non-peptide gonadotropin-releasing hormone (GnRH) receptor antagonist that inhibits endogenous GnRH signalling by binding competitively to GnRH receptors in the pituitary gland, thereby modulating the hypothalamic-pituitary-gonadal axis.
  • Molecular weight: 508.42
  • Formula: C22H15F3N2O7S
  • CLOGP: 5.31
  • LIPINSKI: 1
  • HAC: 9
  • HDO: 2
  • TPSA: 114.40
  • ALOGS: -5.41
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

linzagolix