dexamethasone isonicotinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| prednisone and prednisolone derivatives | 5675 | 2265-64-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An anti-inflammatory
|
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 0.08 mg/mL | Bocci G, Oprea TI, Benet LZ |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
| FDA EPC | N0000175576 | Corticosteroid |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000932 | Antiemetics |
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D018931 | Antineoplastic Agents, Hormonal |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D005765 | Gastrointestinal Agents |
| MeSH PA | D005938 | Glucocorticoids |
| MeSH PA | D006728 | Hormones |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D018926 | Anti-Allergic Agents |
| CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
| CHEBI has role | CHEBI:35610 | antineoplastic agents |
| CHEBI has role | CHEBI:35703 | Xenobiotic |
| CHEBI has role | CHEBI:35705 | immunosuppressive agents |
| CHEBI has role | CHEBI:37962 | adrenergic agents |
| CHEBI has role | CHEBI:50919 | antiemetico |
| CHEBI has role | CHEBI:78298 | environmental contaminants |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cats | Inflammation | Indication |
| Cattle | Primary bovine ketosis | Indication |
| Cattle | Inflammation | Indication |
| Dogs | Inflammation | Indication |
| Horses | Inflammation | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Voren Suspension | Boehringer lngelheim Animal Health USA Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEBI:41879 | CHEBI |
| DEX | PDB_CHEM_ID |
| DB11487 | DRUGBANK_ID |
| DB01234 | DRUGBANK_ID |
| 002174 | NDDF |
| 003957 | NDDF |
| 4017922 | VANDF |
| D003908 | MESH_DESCRIPTOR_UI |
| C0011779 | UMLSCUI |
| C0011777 | UMLSCUI |
| 372584003 | SNOMEDCT_US |
| 7561000 | SNOMEDCT_US |
| 768495008 | SNOMEDCT_US |
| 816 | INN_ID |
| D07797 | KEGG_DRUG |
| 61274 | PUBCHEM_CID |
| 5743 | PUBCHEM_CID |
| 3264 | RXNORM |
| 4552 | MMSL |
| 6848 | MMSL |
| d00206 | MMSL |
| D003907 | MESH_DESCRIPTOR_UI |
| 8LGC0BOA71 | UNII |
Pharmaceutical products:
None