deslorelin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
pituitary hormone-release stimulating peptides 5673 57773-65-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • deslorelin
  • deslorelin acetate
Ovuplant is tradename for short-term-release implant containing deslorelin acetate
  • Molecular weight: 1282.48
  • Formula: C64H83N17O12
  • CLOGP: -3.23
  • LIPINSKI: 3
  • HAC: 29
  • HDO: 17
  • TPSA: 444.83
  • ALOGS: -4.62
  • ROTB: 32

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D004791 Enzyme Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

SpeciesUseRelation
Horses Induction of ovulation Indication

🐶 Veterinary products

ProductApplicantIngredients
Ovuplant Virbac AH Inc. 1
SucroMate Equine Dechra, Ltd. 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Gonadotropin-releasing hormone receptor GPCR AGONIST Kd 10 IUPHAR

External reference:

IDSource
CHEMBL2365665 ChEMBL_ID
C066438 MESH_SUPPLEMENTAL_RECORD_UI
9343 IUPHAR_LIGAND_ID
DB11510 DRUGBANK_ID
018504 NDDF
018505 NDDF
C0083220 UMLSCUI
6461 INN_ID
720017007 SNOMEDCT_US
82318-06-7 SECONDARY_CAS_RN
D03694 KEGG_DRUG
25077495 PUBCHEM_CID
1311743 RXNORM
TKG3I66TVE UNII

Pharmaceutical products:

None