carbadox 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antibacterials, quinazoline dioxide derivatives | 5657 | 6804-07-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An antibacterial agent that has been used in veterinary practice for treating swine dysentery and enteritis and for promoting growth. However, its use has been prohibited in the UK following reports of carcinogenicity and mutagenicity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p125)
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000891 | Anti-Infective Agents, Local |
| MeSH PA | D002273 | Carcinogens |
| MeSH PA | D009153 | Mutagens |
| MeSH PA | D009676 | Noxae |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Swine | To increase rate of weight gain | Indication |
| Swine | To improve feed efficiency | Indication |
| Swine | Dysentery (vibrionic dysentery, bloody scours, or hemorrhagic dysentery) | Indication |
| Swine | Bacterial swine enteritis | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Mecadox Premix 10 | Phibro Animal Health Corp. | 1 |
| Banminth / Mecadox | Phibro Animal Health Corp. | 2 |
| Mecadox and Terramycin | Phibro Animal Health Corp. | 2 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEMBL13779 | ChEMBL_ID |
| D002218 | MESH_DESCRIPTOR_UI |
| C0006947 | UMLSCUI |
| 2487 | INN_ID |
| 96016007 | SNOMEDCT_US |
| 6804-07-5 | SECONDARY_CAS_RN |
| D03382 | KEGG_DRUG |
| 135511839 | PUBCHEM_CID |
| 1314339 | RXNORM |
| M2X04R2E2Y | UNII |
Pharmaceutical products:
None