capromorelin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
growth hormone release-stimulating peptides	5656	193273-66-4

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

capromorelin
CP-424391
capimorelin
capromorelin tartrate

A growth hormone secretagogue

Molecular weight: 505.62
Formula: C28H35N5O4
CLOGP: 2.70
LIPINSKI: 1
HAC: 9
HDO: 2
TPSA: 117.33
ALOGS: -4.40
ROTB: 9

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

Species	Use	Relation
Dogs	Appetite stimulation	Indication

🐶 Veterinary products

Product	Applicant	Ingredients
ENTYCE	Elanco US Inc.	1
Elura	Elanco US Inc.	1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Growth hormone secretagogue receptor type 1	GPCR	Q92847	GHSR_HUMAN		Ki	8.15		CHEMBL
Growth hormone secretagogue receptor type 1	GPCR		GHSR_RAT		EC50	8.52		CHEMBL

External reference:

ID	Source
CHEMBL113313	ChEMBL_ID
C433143	MESH_SUPPLEMENTAL_RECORD_UI
193273-69-7	SECONDARY_CAS_RN
DB15205	DRUGBANK_ID
018032	NDDF
018033	NDDF
C1259613	UMLSCUI
7901	INN_ID
D03373	KEGG_DRUG
216208	PUBCHEM_CID
1986787	RXNORM
0MQ44VUN84	UNII

Pharmaceutical products:

None