DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
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L1000
FAQ
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
capromorelin 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
growth hormone release-stimulating peptides
5656
193273-66-4
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
capromorelin
CP-424391
capimorelin
capromorelin tartrate
A growth hormone secretagogue
Molecular weight: 505.62
Formula: C28H35N5O4
CLOGP: 2.70
LIPINSKI: 1
HAC: 9
HDO: 2
TPSA: 117.33
ALOGS: -4.40
ROTB: 9
Drug dosage:
None
ADMET properties:
None
Approvals:
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Agency
Company
Orphan
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FDA
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
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Species
Use
Relation
Dogs
Appetite stimulation
Indication
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🐶 Veterinary products
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Product
Applicant
Ingredients
Elura
Elanco US Inc.
1
ENTYCE
Elanco US Inc.
1
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Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Growth hormone secretagogue receptor type 1
GPCR
Q92847
GHSR_HUMAN
Ki
8.15
CHEMBL
Growth hormone secretagogue receptor type 1
GPCR
GHSR_RAT
EC50
8.52
CHEMBL
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External reference:
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ID
Source
018032
NDDF
018033
NDDF
0MQ44VUN84
UNII
193273-69-7
SECONDARY_CAS_RN
1986787
RXNORM
216208
PUBCHEM_CID
7901
INN_ID
C1259613
UMLSCUI
C433143
MESH_SUPPLEMENTAL_RECORD_UI
CHEMBL113313
ChEMBL_ID
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Pharmaceutical products:
None
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capromorelin