potassium bromide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5650 7758-02-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • potassium bromide
  • Molecular weight: 119.00
  • Formula: BrK
  • CLOGP: -1.32
  • LIPINSKI: 0
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS:
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hyperammonaemia 35.09 35.05 7 205 5225 63483585

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Status epilepticus 75.71 51.20 18 266 12596 34944051

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Status epilepticus 56.73 44.21 15 396 25026 79718951

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

ProductApplicantIngredients
KBroVet-CA1 Pegasus Laboratories Inc. 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Carbonic anhydrase 4 Enzyme Ki 4.05 CHEMBL

External reference:

IDSource
CHEBI:32030 CHEBI
K PDB_CHEM_ID
CHEMBL1644030 ChEMBL_ID
C039004 MESH_SUPPLEMENTAL_RECORD_UI
005010 NDDF
C0071754 UMLSCUI
DB01345 DRUGBANK_ID
DB06715 DRUGBANK_ID
35903003 SNOMEDCT_US
421196003 SNOMEDCT_US
7758-02-3 SECONDARY_CAS_RN
D01731 KEGG_DRUG
253877 PUBCHEM_CID
34299 RXNORM
NOCODE MMSL
OSD78555ZM UNII

Pharmaceutical products:

None