xylazine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5644 | 7361-61-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An adrenergic alpha-2 agonist used as sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:35569 | alpha-adrenergic agonists |
| CHEBI has role | CHEBI:35717 | hypnotics |
| CHEBI has role | CHEBI:51371 | muscle relaxants |
| CHEBI has role | CHEBI:149552 | emetics |
| MeSH PA | D018663 | Adrenergic Agents |
| MeSH PA | D000322 | Adrenergic Agonists |
| MeSH PA | D058647 | Adrenergic alpha-2 Receptor Agonists |
| MeSH PA | D000316 | Adrenergic alpha-Agonists |
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D002492 | Central Nervous System Depressants |
| MeSH PA | D006993 | Hypnotics and Sedatives |
| MeSH PA | D009125 | Muscle Relaxants, Central |
| MeSH PA | D009465 | Neuromuscular Agents |
| MeSH PA | D018377 | Neurotransmitter Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D018689 | Sensory System Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cervidae | Preanesthesia to general anesthesia | Indication |
| Cats | Sedation | Indication |
| Cats | Preanesthesia to general anesthesia | Indication |
| Cats | Preanesthesia to general local anesthesia | Indication |
| Dogs | Sedation | Indication |
| Dogs | Preanesthesia to general anesthesia | Indication |
| Dogs | Preanesthesia to general local anesthesia | Indication |
| Horses | Sedation | Indication |
| Horses | Preanesthesia to general anesthesia | Indication |
| Horses | Preanesthesia to general local anesthesia | Indication |
| Cervidae | Sedation | Indication |
| Cervidae | To calm and facilitate handling of fractious animals | Indication |
| Cervidae | Pain following injury or surgery | Indication |
| Cervidae | Preanesthesia to general local anesthesia | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Rompun Injectable (20 mg) | Dechra, Ltd. | 1 |
| Rompun Injectable (100 mg) | Dechra, Ltd. | 1 |
| Anased | Akorn Animal Health Inc. | 1 |
| Xylazine HCl Injection | Cronus Pharma Specialities India Private Limited | 1 |
| Sedazine | Boehringer lngelheim Animal Health USA Inc. | 1 |
| Chanazine | Chanelle Pharmaceuticals Manufacturing Ltd. | 1 |
| Chanazine | Chanelle Pharmaceuticals Manufacturing Ltd. | 1 |
| XylaMed | Bimeda Animal Health Limited | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEBI:92386 | CHEBI |
| CHEMBL297362 | ChEMBL_ID |
| 523 | IUPHAR_LIGAND_ID |
| DB11477 | DRUGBANK_ID |
| 018579 | NDDF |
| 018580 | NDDF |
| D014991 | MESH_DESCRIPTOR_UI |
| C0043366 | UMLSCUI |
| CHEMBL1256022 | ChEMBL_ID |
| 2663 | INN_ID |
| 782177004 | SNOMEDCT_US |
| 96230006 | SNOMEDCT_US |
| 23076-35-9 | SECONDARY_CAS_RN |
| D08683 | KEGG_DRUG |
| 5707 | PUBCHEM_CID |
| 1099660 | RXNORM |
| 2KFG9TP5V8 | UNII |
Pharmaceutical products:
None