thiostrepton 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5627 | 1393-48-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
One of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000900 | Anti-Bacterial Agents |
| MeSH PA | D000890 | Anti-Infective Agents |
| CHEBI has role | CHEBI:25212 | metabolites |
| CHEBI has role | CHEBI:35610 | antineoplastic agents |
| CHEBI has role | CHEBI:36047 | antibacterial drugs |
| CHEBI has role | CHEBI:48001 | protein synthesis inhibitors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cats | Superficial bacterial infections | Indication |
| Cats | Dermatologic disorders associated with bacterial or candidal (Candida albicans) infections | Indication |
| Dogs | Superficial bacterial infections | Indication |
| Dogs | Dermatologic disorders associated with bacterial or candidal (Candida albicans) infections | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Panolog Ointment | Zoetis Inc. | 4 |
| Panolog Cream | Zoetis Inc. | 4 |
| DERMA-VET Ointment | Med-Pharmex Inc. | 4 |
| Animax Ointment | Fougera Pharmaceuticals Inc. | 4 |
| Derma 4 Ointment | Zoetis Inc. | 4 |
| Derm-Otic Ointment | Zoetis Inc. | 4 |
| Derma-Vet Cream | Med-Pharmex Inc. | 4 |
| Animax Cream | Fougera Pharmaceuticals Inc. | 4 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEBI:29693 | CHEBI |
| CHEMBL1236460 | ChEMBL_ID |
| CHEMBL468719 | ChEMBL_ID |
| CHEMBL2303629 | ChEMBL_ID |
| DB11467 | DRUGBANK_ID |
| 017745 | NDDF |
| D013883 | MESH_DESCRIPTOR_UI |
| C0039947 | UMLSCUI |
| 96017003 | SNOMEDCT_US |
| D06111 | KEGG_DRUG |
| 16129666 | PUBCHEM_CID |
| 1365970 | RXNORM |
| HR4S203Y18 | UNII |
Pharmaceutical products:
None