selamectin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiparasitics, ivermectin derivatives 5617 220119-17-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • selamectin
  • UK-124114
  • revolution
A broad-spectrum endectocide;
  • Molecular weight: 769.97
  • Formula: C43H63NO11
  • CLOGP: 4.26
  • LIPINSKI: 3
  • HAC: 12
  • HDO: 3
  • TPSA: 154.73
  • ALOGS: -5.26
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000977 Antiparasitic Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

SpeciesUseRelation
Cats Kills adult fleas Indication
Cats Prevent flea eggs from hatching Indication
Cats Flea infestations caused by Ctenocephalides felis Indication
Cats Prevention of heartworm disease caused by Dirofilaria immitis Indication
Cats Ear mite (Otodectes cynotis) infestations Indication
Cats Treatment and control of roundworms, Toxocara cati Indication
Cats Treatment and control of intestinal hookworms, infections with Ancylostoma tubaeforme Indication
Dogs Kills adult fleas Indication
Dogs Prevent flea eggs from hatching Indication
Dogs Flea infestations caused by Ctenocephalides felis Indication
Dogs Prevention of heartworm disease caused by Dirofilaria immitis Indication
Dogs Ear mite infestations with Otodectes cynotis Indication
Dogs Treatment and control of sarcoptic mange, Sarcoptes scabiei Indication
Dogs Tick infestations caused by Dermacentor variabilis Indication

🐶 Veterinary products

ProductApplicantIngredients
Revolution Zoetis Inc. 1
revolution PLUS Zoetis Inc. 2
Selarid Norbrook Laboratories, Ltd. 1
SENERGY Chanelle Pharmaceuticals Manufacturing Ltd. 1
Revolt Aurora Pharmaceutical Inc. 1
SelaSpot Bimeda Animal Health Limited 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEMBL1908325 ChEMBL_ID
C414354 MESH_SUPPLEMENTAL_RECORD_UI
DB11459 DRUGBANK_ID
017786 NDDF
C0961275 UMLSCUI
7888 INN_ID
D05813 KEGG_DRUG
9578507 PUBCHEM_CID
1044269 RXNORM
A2669OWX9N UNII

Pharmaceutical products:

None