sarolaner 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antagonists of GABA (gamma-aminobutyric acid) regulated chloride channels, antiparasitic agents | 5616 | 1398609-39-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An antiparasitic agent against ticks
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cats | Kill adult fleas, Ctenocephalides felis | Indication |
| Cats | Flea infestations | Indication |
| Cats | Tick infestations with Ixodes scapularis (black-legged tick) | Indication |
| Cats | Treatment and control of tick infestations with Amblyomma americanum (lone star tick) | Indication |
| Cats | Treatment and control of tick infestations with Dermacentor variabilis (American dog tick) | Indication |
| Cats | Ear mite (Otodectes cynotis) infestations | Indication |
| Dogs | Kill adult fleas, Ctenocephalides felis | Indication |
| Dogs | Flea infestations | Indication |
| Dogs | Treatment and control of tick infestations with Amblyomma americanum (lone star tick) | Indication |
| Dogs | Treatment and control of tick infestations with Amblyomma americanum (lone star tick) | Indication |
| Dogs | Treatment and control of tick infestations with Dermacentor variabilis (American dog tick) | Indication |
| Dogs | Tick infestations with Ixodes scapularis (black-legged tick) | Indication |
| Dogs | Tick infestations with Rhipicephalus sanguineus (brown dog tick) | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Simparica | Zoetis Inc. | 1 |
| revolution PLUS | Zoetis Inc. | 2 |
| Simparica Trio | Zoetis Inc. | 3 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEMBL3137302 | ChEMBL_ID |
| C000623191 | MESH_SUPPLEMENTAL_RECORD_UI |
| 017790 | NDDF |
| C4083583 | UMLSCUI |
| 9923 | INN_ID |
| D10668 | KEGG_DRUG |
| 73169092 | PUBCHEM_CID |
| 1740360 | RXNORM |
| DM113FTW7F | UNII |
Pharmaceutical products:
None