oxfendazole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| anthelminthics, tiabendazole derivatives | 5594 | 53716-50-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000871 | Anthelmintics |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000969 | Antinematodal Agents |
| MeSH PA | D000977 | Antiparasitic Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cattle | Removal and control of lungworms, Dictyocaulus viviparus (adult, L4) | Indication |
| Cattle | Removal and control of barberpole worms, Haemonchus contortus | Indication |
| Cattle | Removal and control of barberpole worms H placei (adult) | Indication |
| Cattle | Removal and control of small stomach worms, Trichostrongylus axei (adult) | Indication |
| Cattle | Removal and control of brown stomach worms, Ostertagia ostertagi (adult, L4, inhibited L4) | Indication |
| Cattle | Removal and control of intestinal worms | Indication |
| Cattle | Indication | |
| Cattle | Removal and control of nodular worm, Oesophagostomum radiatum (adult) | Indication |
| Cattle | Removal and control of hookworm, Bunostomum phlebotomum (adult) | Indication |
| Cattle | Removal and control of small intestinal worms, Cooperia punctata | Indication |
| Cattle | Removal and control of small intestinal worms, C oncophora | Indication |
| Cattle | Removal and control of small intestinal worms, C surnabada (adult, L4) | Indication |
| Cattle | Removal and control of tapeworms, Moniezia benedeni (adult) | Indication |
| Horses | Removal of the large roundworms, Parascaris equorum | Indication |
| Horses | Removal of the mature and immature pinworms | Indication |
| Horses | Removal of pinworms, Oxyuris equi | Indication |
| Horses | Removal of large strongyles, Strongylus edentatus | Indication |
| Horses | Removal of large strongyles, Strongylus vulgaris | Indication |
| Horses | Removal of large strongyles, Strongylus equinus | Indication |
| Horses | Removal of small strongyles | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Benzelmin Powder For Suspension | Zoetis Inc. | 1 |
| Benzelmin Top Dress. | Zoetis Inc. | 1 |
| Benzelmin Equine Anthelmic Paste, Synanthic Oral Paste | Zoetis Inc. | 1 |
| Benzelmin Equine Anthelmintic Suspension, Synanthic Suspension | Zoetis Inc. | 1 |
| Benzelmin Plus Paste | Zoetis Inc. | 2 |
| Synanthic Bovine Dewormer Suspension 22.5%, Synanthic Bovine Dewormer Suspension 9.06% | Boehringer lngelheim Animal Health USA Inc. | 1 |
| Synanthic Bovine Dewormer Paste, 18.5% | Zoetis Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Adenosine receptor A2a | GPCR | Ki | 6.07 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| CHEMBL42442 | ChEMBL_ID |
| C011030 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB11446 | DRUGBANK_ID |
| C0069761 | UMLSCUI |
| 3853 | INN_ID |
| 96112006 | SNOMEDCT_US |
| D05291 | KEGG_DRUG |
| 40854 | PUBCHEM_CID |
| 1085717 | RXNORM |
| OMP2H17F9E | UNII |
Pharmaceutical products:
None