hygromycin b 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 5556 31282-04-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hygromycin b
  • hygrovetin
Aminoglycoside produced by Streptomyces hygroscopicus. It is used as an anthelmintic against swine infections by large roundworms, nodular worms, and whipworms
  • Molecular weight: 527.52
  • Formula: C20H37N3O13
  • CLOGP: -6.28
  • LIPINSKI: 3
  • HAC: 16
  • HDO: 11
  • TPSA: 272.06
  • ALOGS: -0.39
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000871 Anthelmintics
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000977 Antiparasitic Agents
CHEBI has role CHEBI:35443 anthelmintics

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

SpeciesUseRelation
Chicken Control of large roundworms, Ascaris galli Indication
Chicken Control of fecal worms, Heterakis gallinae Indication
Chicken Control of capillary worms (Capillaria obsignata) Indication
Swine Control of large roundworms, Ascaris suis Indication
Swine Control of nodular worms, Oesophagostomum dentatum Indication
Swine Control of whipworms, Trichuris suis Indication

🐶 Veterinary products

ProductApplicantIngredients
Hygromix 8, Hygromix 2.4 Elanco US Inc. 1
Hygromix 2.4 Elanco US Inc. 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:16976 CHEBI
HYG PDB_CHEM_ID
DB11520 DRUGBANK_ID
D006921 MESH_DESCRIPTOR_UI
C0020406 UMLSCUI
96137001 SNOMEDCT_US
31282-04-9 SECONDARY_CAS_RN
C01925 KEGG_DRUG
56928061 PUBCHEM_CID
1426887 RXNORM
3XQ2233B0B UNII

Pharmaceutical products:

None