halofuginone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5553 55837-20-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • halofuginone
  • HT-100
  • halofuginon
  • halocur
  • halofuginone hydrobromide
  • Molecular weight: 414.68
  • Formula: C16H17BrClN3O3
  • CLOGP: 2.48
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 82
  • ALOGS: -3.56
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D020533 Angiogenesis Inhibitors
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000981 Antiprotozoal Agents
MeSH PA D003049 Coccidiostats
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D006131 Growth Inhibitors
MeSH PA D006133 Growth Substances
MeSH PA D011500 Protein Synthesis Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

SpeciesUseRelation
Chickens Prevention of coccidiosis caused by Eimeria tenella Indication
Chickens Prevention of coccidiosis caused by E necatrix Indication
Chickens Prevention of coccidiosis caused by E acervulina Indication
Chickens Prevention of coccidiosis caused by E maxima Indication
Chickens Prevention of coccidiosis caused by E mivati Indication
Chickens Prevention of coccidiosis caused by E brunetti Indication
Turkeys Prevention of coccidiosis caused by Eimeria adenoeides Indication
Turkeys Prevention of coccidiosis caused by E meleagrimitis Indication
Turkeys Prevention of coccidiosis caused by E gallopavonis Indication

🐶 Veterinary products

ProductApplicantIngredients
Stenorol Huvepharma EOOD 1
Flavomycin / Stenorol Huvepharma EOOD 2
BMD / Stenorol Huvepharma EOOD 2
Stenorol Type A Medicated Article Huvepharma EOOD 1
Flavomycin / Stenorol Huvepharma EOOD 2
BMD / Stenorol Huvepharma EOOD 2
Stenorol and LINCOMIX Huvepharma EOOD 2

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Proline--tRNA ligase, PfPRS, EC 6.1.1.15 Unclassified EC50 9.07 IUPHAR

External reference:

IDSource
HFG PDB_CHEM_ID
CHEMBL1197091 ChEMBL_ID
CHEMBL1199540 ChEMBL_ID
C010176 MESH_SUPPLEMENTAL_RECORD_UI
10153 IUPHAR_LIGAND_ID
DB04866 DRUGBANK_ID
C0062095 UMLSCUI
CHEMBL559362 ChEMBL_ID
3676 INN_ID
96157002 SNOMEDCT_US
64924-67-0 SECONDARY_CAS_RN
D08034 KEGG_DRUG
456390 PUBCHEM_CID
L31MM1385E UNII

Pharmaceutical products:

None