fluralaner 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antagonists of GABA (gamma-aminobutyric acid) regulated chloride channels, antiparasitic agents 5547 864731-61-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • fluralaner
  • bravecto
  • AH-252723
  • A-1443
  • Molecular weight: 556.29
  • Formula: C22H17Cl2F6N3O3
  • CLOGP: 4.89
  • LIPINSKI: 2
  • HAC: 6
  • HDO: 2
  • TPSA: 79.79
  • ALOGS: -5.88
  • ROTB: 8

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

SpeciesUseRelation
Dogs Flea infestations caused by Ctenocephalides felis Indication
Dogs Treatment and control of tick infestations with Ixodes scapularis (black-legged tick) Indication
Dogs Treatment and control of tick infestations with Amblyomma americanum (lone star tick) Indication
Dogs Treatment and control of tick infestations with Rhipicephalus sanguineus (brown dog tick)] Indication
Dogs Treatment and control of tick infestations with Dermacentor variabilis (American dog tick) Indication

🐶 Veterinary products

ProductApplicantIngredients
BRAVECTO Intervet Inc. 1
BRAVECTO Intervet Inc. 1
BRAVECTO PLUS Intervet Inc. 2
BRAVECTO 1-MONTH Intervet Inc. 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEMBL2364610 ChEMBL_ID
C000591860 MESH_SUPPLEMENTAL_RECORD_UI
DB11414 DRUGBANK_ID
017805 NDDF
C3831895 UMLSCUI
CHEMBL2219412 ChEMBL_ID
9485 INN_ID
D10402 KEGG_DRUG
25144319 PUBCHEM_CID
1538098 RXNORM
WSH8393RM5 UNII

Pharmaceutical products:

None