ethopabate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	5536	59-06-3

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

ethopabate

An inhibitor of folate metabolism. It is used as coccidiostat in poultry

Molecular weight: 237.26
Formula: C12H15NO4
CLOGP: 1.94
LIPINSKI: 0
HAC: 5
HDO: 1
TPSA: 64.63
ALOGS: -2.70
ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000977	Antiparasitic Agents
MeSH PA	D000981	Antiprotozoal Agents
MeSH PA	D003049	Coccidiostats

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

Species	Use	Relation
Chicken	Prevention of coccidiosis where severe exposure to coccidiosis from E acervulina	Indication
Chicken	Prevention of coccidiosis where severe exposure to coccidiosis from E maxima	Indication
Chicken	Prevention of coccidiosis where severe exposure to coccidiosis from E brunette	Indication

🐶 Veterinary products

Product	Applicant	Ingredients
Amprol Hi-E, Amprol Plus	Huvepharma EOOD	2
Amprol HI-E Plus	Huvepharma EOOD	3
Amprol Plus and Aureomycin	Zoetis Inc.	3
Amprol HI-E & Bambermycins, Amprol HI-E / Flavomycin	Huvepharma EOOD	3
Baciferm / Amprol HI-E Premix	Zoetis Inc.	3
Albac / Amprol Hi-E	Zoetis Inc.	3

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Neuraminidase	Enzyme		B4URF0_9INFA		IC50	6.66		CHEMBL

External reference:

ID	Source
CHEMBL458769	ChEMBL_ID
D005011	MESH_DESCRIPTOR_UI
C0015041	UMLSCUI
96147003	SNOMEDCT_US
D08916	KEGG_DRUG
6034	PUBCHEM_CID
1314353	RXNORM
F4X3L6068O	UNII

Pharmaceutical products:

None